TreeWAS – Variant ID: rs4148876

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
M20-M25 Other joint disorders	0.999	0.001	0.000
M35 Other systemic involvement of connective tissue	0.999	0.001	0.000
M35.3 Polymyalgia rheumatica	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
E14.9 Without complications	0.998	0.002	0.000
J33 Nasal polyp	0.997	0.003	0.000
J33.9 Nasal polyp, unspecified	0.996	0.004	0.000
J30-J39 Other diseases of upper respiratory tract	0.993	0.007	0.000
Chapter X Diseases of the respiratory system	0.993	0.007	0.000
Chapter VIII Diseases of the ear and mastoid process	0.991	0.009	0.000
Chapter VII Diseases of the eye and adnexa	0.984	0.016	0.000
J33.0 Polyp of nasal cavity	0.981	0.019	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.981	0.019	0.000
M80-M85 Disorders of bone density and structure	0.979	0.021	0.000
Chapter XX External causes of morbidity and mortality	0.976	0.024	0.000
H65-H75 Diseases of middle ear and mastoid	0.975	0.025	0.000
E10.4 With neurological complications	0.963	0.037	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.960	0.040	0.000
H30-H36 Disorders of choroid and retina	0.957	0.043	0.000
K90.0 Coeliac disease	0.000	0.045	0.955
H36 Retinal disorders in diseases classified elsewhere	0.953	0.047	0.000
M31 Other necrotising vasculopathies	0.953	0.047	0.000
H36.0 Diabetic retinopathy	0.951	0.049	0.000
H53-H54 Visual disturbances and blindness	0.951	0.049	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.950	0.050	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.949	0.051	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.947	0.053	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.946	0.054	0.000
H54 Blindness and low vision	0.942	0.058	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.937	0.063	0.000
E16 Other disorders of pancreatic internal secretion	0.932	0.068	0.000
M84 Disorders of continuity of bone	0.923	0.077	0.000
H66 Suppurative and unspecified otitis media	0.922	0.078	0.000
M05 Seropositive rheumatoid arthritis	0.920	0.080	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.918	0.082	0.000
E16.2 Hypoglycaemia, unspecified	0.912	0.088	0.000
J40-J47 Chronic lower respiratory diseases	0.911	0.089	0.000
J45 Asthma	0.908	0.092	0.000
J45.9 Asthma, unspecified	0.905	0.095	0.000
M06.3 Rheumatoid nodule	0.903	0.097	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.902	0.097	0.000
S50-S59 Injuries to the elbow and forearm	0.900	0.100	0.000
E14.3 With ophthalmic complications	0.898	0.102	0.000
M65-M68 Disorders of synovium and tendon	0.895	0.105	0.000
M31.6 Other giant cell arteritis	0.888	0.112	0.000
E10.5 With peripheral circulatory complications	0.884	0.116	0.000
W00-W19 Falls	0.880	0.120	0.000
M80 Osteoporosis with pathological fracture	0.876	0.124	0.000
E10.2 With renal complications	0.874	0.126	0.000
H54.4 Blindness, one eye	0.874	0.126	0.000
L05 Pilonidal cyst	0.870	0.130	0.000
V20-V29 Motorcycle rider injured in transport accident	0.865	0.135	0.000
M35.1 Other overlap syndromes	0.865	0.135	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.863	0.137	0.000
T66-T78 Other and unspecified effects of external causes	0.861	0.139	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.858	0.142	0.000
H60-H62 Diseases of external ear	0.856	0.144	0.000
H54.7 Unspecified visual loss	0.854	0.146	0.000
M34 Systemic sclerosis	0.850	0.150	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.850	0.150	0.000
T79-T79 Certain early complications of trauma	0.850	0.150	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.845	0.155	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.844	0.156	0.000
H65 Nonsuppurative otitis media	0.843	0.157	0.000
J33.8 Other polyp of sinus	0.840	0.160	0.000
Chapter VI Diseases of the nervous system	0.840	0.160	0.000
S90-S99 Injuries to the ankle and foot	0.838	0.161	0.000
M86-M90 Other osteopathies	0.833	0.167	0.000
H90-H95 Other disorders of ear	0.830	0.170	0.000
V10-V19 Pedal cyclist injured in transport accident	0.830	0.170	0.000
M00-M03 Infectious arthropathies	0.826	0.174	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.823	0.177	0.000
H66.9 Otitis media, unspecified	0.823	0.177	0.000
H54.0 Blindness, both eyes	0.822	0.178	0.000
M60-M63 Disorders of muscles	0.822	0.178	0.000
W20-W49 Exposure to inanimate mechanical forces	0.817	0.183	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.817	0.183	0.000
M65 Synovitis and tenosynovitis	0.815	0.185	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.813	0.186	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.812	0.188	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.810	0.190	0.000
L05.0 Pilonidal cyst with abscess	0.808	0.192	0.000
E14.6 With other specified complications	0.806	0.194	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.194	0.806
G00-G09 Inflammatory diseases of the central nervous system	0.803	0.197	0.000
M21 Other acquired deformities of limbs	0.802	0.197	0.000
S20-S29 Injuries to the thorax	0.802	0.198	0.000
H66.3 Other chronic suppurative otitis media	0.802	0.198	0.000
H74 Other disorders of middle ear and mastoid	0.802	0.198	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.802	0.198	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.801	0.199	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.801	0.199	0.000
E10.8 With unspecified complications	0.799	0.201	0.000
M30 Polyarteritis nodosa and related conditions	0.798	0.202	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.798	0.202	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.794	0.206	0.000
M81 Osteoporosis without pathological fracture	0.793	0.207	0.000
W07 Fall involving chair	0.793	0.207	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.792	0.207	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.791	0.209	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.788	0.212	0.000
W50-W64 Exposure to animate mechanical forces	0.784	0.216	0.000
S70-S79 Injuries to the hip and thigh	0.782	0.218	0.000
H20 Iridocyclitis	0.780	0.220	0.000
K51 Ulcerative colitis	0.000	0.221	0.779
H54.9 Unspecified visual impairment (binocular)	0.777	0.223	0.000
M06.0 Seronegative rheumatoid arthritis	0.776	0.224	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.775	0.225	0.000
M84.0 Malunion of fracture	0.775	0.225	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.775	0.225	0.000
H92 Otalgia and effusion of ear	0.775	0.225	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.774	0.226	0.000
J38.0 Paralysis of vocal cords and larynx	0.772	0.228	0.000
X60-X84 Intentional self-harm	0.769	0.231	0.000
G80 Infantile cerebral palsy	0.769	0.231	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.768	0.232	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.767	0.233	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.766	0.234	0.000
S10-S19 Injuries to the neck	0.765	0.235	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.765	0.235	0.000
J95-J99 Other diseases of the respiratory system	0.765	0.235	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.764	0.236	0.000
M91-M94 Chondropathies	0.761	0.239	0.000
H04 Disorders of lachrymal system	0.761	0.239	0.000
J45.0 Predominantly allergic asthma	0.760	0.240	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.759	0.241	0.000
E10.0 With coma	0.758	0.242	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.756	0.244	0.000
T78 Adverse effects, not elsewhere classified	0.756	0.244	0.000
S51 Open wound of forearm	0.754	0.246	0.000
M31.3 Wegener's granulomatosis	0.753	0.247	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.753	0.247	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.752	0.248	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.749	0.251	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.748	0.252	0.000
J42 Unspecified chronic bronchitis	0.748	0.252	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.747	0.253	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.253	0.747
Y00-Y09 Assault	0.742	0.258	0.000
J36 Peritonsillar abscess	0.740	0.260	0.000
V40-V49 Car occupant injured in transport accident	0.740	0.260	0.000
H16 Keratitis	0.740	0.260	0.000
J38.6 Stenosis of larynx	0.737	0.263	0.000
M06.34 Rheumatoid nodule (Hand)	0.737	0.263	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.735	0.265	0.000
M06.4 Inflammatory polyarthropathy	0.734	0.266	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.731	0.269	0.000
H73 Other disorders of tympanic membrane	0.730	0.269	0.000
H01 Other inflammation of eyelid	0.728	0.272	0.000
M86 Osteomyelitis	0.726	0.274	0.000
V01-V09 Pedestrian injured in transport accident	0.726	0.274	0.000
S54 Injury of nerves at forearm level	0.726	0.274	0.000
M33 Dermatopolymyositis	0.725	0.275	0.000
H15 Disorders of sclera	0.725	0.275	0.000
K51.8 Other ulcerative colitis	0.000	0.276	0.724
W22 Striking against or struck by other objects	0.724	0.276	0.000
G82 Paraplegia and tetraplegia	0.724	0.276	0.000
H61 Other disorders of external ear	0.722	0.278	0.000
W08 Fall involving other furniture	0.721	0.279	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.721	0.279	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.721	0.279	0.000
G80.9 Infantile cerebral palsy, unspecified	0.719	0.281	0.000
H69 Other disorders of Eustachian tube	0.718	0.282	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
E14.8 With unspecified complications	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.5 With peripheral circulatory complications	0.717	0.283	0.000
E14.4 With neurological complications	0.717	0.283	0.000
E14.2 Withrenal complications	0.717	0.283	0.000
E14.1 With ketoacidosis	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M35.7 Hypermobility syndrome	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.283	0.000
M32 Systemic lupus erythematosus	0.716	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.716	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.716	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.716	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.716	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.716	0.283	0.000
M35.2 Behcet's disease	0.716	0.283	0.000
X10-X19 Contact with heat and hot substances	0.716	0.284	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.716	0.284	0.000
M14 Arthropathies in other diseases classified elsewhere	0.716	0.284	0.000
H71 Cholesteatoma of middle ear	0.715	0.285	0.000
J33.1 Polypoid sinus degeneration	0.715	0.285	0.000
J32 Chronic sinusitis	0.713	0.287	0.000
E13 Other specified diabetes mellitus	0.713	0.287	0.000
M35.0 Sicca syndrome [Sjogren]	0.713	0.287	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.713	0.287	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.712	0.288	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.709	0.291	0.000
H00 Hordeolum and chalazion	0.708	0.292	0.000
H66.4 Suppurative otitis media, unspecified	0.707	0.293	0.000
H72 Perforation of tympanic membrane	0.707	0.293	0.000
M65.3 Trigger finger	0.707	0.293	0.000
M82 Osteoporosis in diseases classified elsewhere	0.706	0.294	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.706	0.294	0.000
W10 Fall on and from stairs and steps	0.705	0.295	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.704	0.296	0.000
H04.1 Other disorders of lachrymal gland	0.704	0.296	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.703	0.297	0.000
T33-T35 Frostbite	0.703	0.297	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297	0.000
M83 Adult osteomalacia	0.702	0.298	0.000
M00 Pyogenic arthritis	0.702	0.298	0.000
T00-T07 Injuries involving multiple body regions	0.700	0.300	0.000
Y35-Y36 Legal intervention and operations of war	0.700	0.300	0.000
Y10-Y34 Event of undetermined intent	0.700	0.300	0.000
X85-X99 Assault	0.700	0.300	0.000
X30-X39 Exposure to forces of nature	0.700	0.300	0.000
X00-X09 Exposure to smoke, fire and flames	0.700	0.300	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300	0.000
W75-W84 Other accidental threats to breathing	0.700	0.300	0.000
W65-W74 Accidental drowning and submersion	0.700	0.300	0.000
V98-V99 Other and unspecified transport accidents	0.700	0.300	0.000
V95-V97 Air and space transport accidents	0.700	0.300	0.000
V90-V94 Water transport accidents	0.700	0.300	0.000
V70-V79 Bus occupant injured in transport accident	0.700	0.300	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.699	0.301	0.000
H68 Eustachian salpingitis and obstruction	0.699	0.301	0.000
H67 Otitis media in diseases classified elsewhere	0.699	0.301	0.000
M34.8 Other forms of systemic sclerosis	0.698	0.302	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302	0.000
W15 Fall from cliff	0.697	0.303	0.000
S52 Fracture of forearm	0.697	0.303	0.000
M21.0 Valgus deformity, not elsewhere classified	0.697	0.303	0.000
S50 Superficial injury of forearm	0.697	0.303	0.000
H92.0 Otalgia	0.697	0.303	0.000
H70 Mastoiditis and related conditions	0.696	0.304	0.000
J39 Other diseases of upper respiratory tract	0.695	0.305	0.000
L10-L14 Bullous disorders	0.694	0.306	0.000
L60-L75 Disorders of skin appendages	0.694	0.306	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.692	0.308	0.000
M66 Spontaneous rupture of synovium and tendon	0.692	0.308	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.692	0.308	0.000
S32 Fracture of lumbar spine and pelvis	0.691	0.309	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.691	0.309	0.000
S92 Fracture of foot, except ankle	0.691	0.309	0.000
H17 Corneal scars and opacities	0.690	0.310	0.000
M34.9 Systemic sclerosis, unspecified	0.690	0.310	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.690	0.310	0.000
E15 Nondiabetic hypoglycaemic coma	0.688	0.312	0.000
E40-E46 Malnutrition	0.688	0.312	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.687	0.313	0.000
S59 Other and unspecified injuries of forearm	0.687	0.313	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.686	0.314	0.000
H30 Chorioretinal inflammation	0.686	0.314	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.684	0.316	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.683	0.316	0.000
M31.9 Necrotising vasculopathy, unspecified	0.683	0.317	0.000
M31.8 Other specified necrotising vasculopathies	0.683	0.317	0.000
M31.7 Microscopic polyangiitis	0.683	0.317	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.683	0.317	0.000
M31.2 Lethal midline granuloma	0.683	0.317	0.000
M31.1 Thrombotic microangiopathy	0.683	0.317	0.000
M31.0 Hypersensitivity angiitis	0.683	0.317	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.683	0.317	0.000
H60 Otitis externa	0.681	0.319	0.000
M24 Other specific joint derangements	0.681	0.319	0.000
T75 Effects of other external causes	0.680	0.320	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.680	0.320	0.000
L04 Acute lymphadenitis	0.679	0.321	0.000
L01 Impetigo	0.679	0.321	0.000
L00 Staphylococcal scalded skin syndrome	0.679	0.321	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.678	0.322	0.000
X50-X57 Overexertion, travel and privation	0.677	0.322	0.000
M85 Other disorders of bone density and structure	0.677	0.323	0.000
G82.2 Paraplegia, unspecified	0.677	0.323	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.677	0.323	0.000
H54.6 Unqualified visual loss, one eye	0.676	0.324	0.000
H54.5 Low vision, one eye	0.676	0.324	0.000
H54.3 Unqualified visual loss, both eyes	0.676	0.324	0.000
H54.2 Low vision, both eyes	0.676	0.324	0.000
H54.1 Blindness, one eye, low vision, other eye	0.676	0.324	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.675	0.325	0.000
L20-L30 Dermatitis and eczema	0.675	0.325	0.000
H34 Retinal vascular occlusions	0.675	0.325	0.000
H74.4 Polyp of middle ear	0.673	0.327	0.000
M81.4 Drug-induced osteoporosis	0.673	0.327	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.673	0.327	0.000
H74.0 Tympanosclerosis	0.672	0.328	0.000
V23.4 Driver injured in traffic accident	0.672	0.328	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.672	0.328	0.000
W17 Other fall from one level to another	0.672	0.328	0.000
M62 Other disorders of muscle	0.672	0.328	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.668	0.332	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.668	0.332	0.000
E16.4 Abnormal secretion of gastrin	0.668	0.332	0.000
E16.3 Increased secretion of glucagon	0.668	0.332	0.000
E16.1 Other hypoglycaemia	0.668	0.332	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.668	0.332	0.000
H21 Other disorders of iris and ciliary body	0.668	0.332	0.000
W07.5 Trade and service area	0.665	0.335	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.664	0.336	0.000
S80-S89 Injuries to the knee and lower leg	0.663	0.337	0.000
H92.1 Otorrhoea	0.663	0.337	0.000
H20.8 Other iridocyclitis	0.663	0.337	0.000
S51.9 Open wound of forearm, part unspecified	0.662	0.338	0.000
M84.9 Disorder of continuity of bone, unspecified	0.662	0.338	0.000
M84.8 Other disorders of continuity of bone	0.662	0.338	0.000
M84.3 Stress fracture, not elsewhere classified	0.662	0.338	0.000
M84.2 Delayed union of fracture	0.662	0.338	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.661	0.339	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.661	0.339	0.000
H66.0 Acute suppurative otitis media	0.661	0.339	0.000
W13 Fall from, out of or through building or structure	0.660	0.340	0.000
M05.8 Other seropositive rheumatoid arthritis	0.660	0.340	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.660	0.340	0.000
M05.2 Rheumatoid vasculitis	0.660	0.340	0.000
M05.1 Rheumatoid lung disease	0.660	0.340	0.000
M05.0 Felty's syndrome	0.660	0.340	0.000
H18 Other disorders of cornea	0.659	0.341	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.658	0.342	0.000
T14 Injury of unspecified body region	0.655	0.345	0.000
X20-X29 Contact with venomous animals and plants	0.655	0.345	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.653	0.347	0.000
J41 Simple and mucopurulent chronic bronchitis	0.653	0.347	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.652	0.347	0.000
V80-V89 Other land transport accidents	0.652	0.348	0.000
J45.8 Mixed asthma	0.651	0.349	0.000
J45.1 Nonallergic asthma	0.651	0.349	0.000
L05.9 Pilonidal cyst without abscess	0.650	0.350	0.000
J38.4 Oedema of larynx	0.650	0.350	0.000
M86.9 Osteomyelitis, unspecified	0.650	0.350	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.649	0.351	0.000
S99 Other and unspecified injuries of ankle and foot	0.649	0.351	0.000
J37 Chronic laryngitis and laryngotracheitis	0.648	0.352	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.648	0.352	0.000
M06.38 Rheumatoid nodule (Other)	0.648	0.352	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.648	0.352	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.648	0.352	0.000
M06.33 Rheumatoid nodule (Forearm)	0.648	0.352	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.648	0.352	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.648	0.352	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.648	0.352	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.648	0.352	0.000
W07.9 Unspecified place	0.647	0.353	0.000
S90 Superficial injury of ankle and foot	0.647	0.353	0.000
S58 Traumatic amputation of forearm	0.645	0.355	0.000
S57 Crushing injury of forearm	0.645	0.355	0.000
S55 Injury of blood vessels at forearm level	0.645	0.355	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.645	0.355	0.000
S52.0 Fracture of upper end of ulna	0.645	0.355	0.000
G40-G47 Episodic and paroxysmal disorders	0.645	0.355	0.000
H90 Conductive and sensorineural hearing loss	0.644	0.356	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.643	0.357	0.000
W11 Fall on and from ladder	0.642	0.358	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.642	0.358	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.642	0.358	0.000
H31 Other disorders of choroid	0.641	0.359	0.000
S40-S49 Injuries to the shoulder and upper arm	0.641	0.359	0.000
G80.0 Spastic cerebral palsy	0.640	0.360	0.000
G83 Other paralytic syndromes	0.640	0.360	0.000
W28 Contact with powered lawn mower	0.638	0.362	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.637	0.362	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.637	0.363	0.000
M11 Other crystal arthropathies	0.636	0.363	0.000
H61.1 Non-infective disorders of pinna	0.636	0.364	0.000
H01.0 Blepharitis	0.636	0.364	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.635	0.365	0.000
M84.4 Pathological fracture, not elsewhere classified	0.635	0.365	0.000
H04.8 Other disorders of lachrymal system	0.634	0.366	0.000
H20.0 Acute and subacute iridocyclitis	0.634	0.366	0.000
J60-J70 Lung diseases due to external agents	0.632	0.367	0.000
M40-M43 Deforming dorsopathies	0.631	0.369	0.000
M13 Other arthritis	0.631	0.369	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.631	0.369	0.000
W14 Fall from tree	0.631	0.369	0.000
W12 Fall on and from scaffolding	0.631	0.369	0.000
W09 Fall involving playground equipment	0.631	0.369	0.000
W05 Fall involving wheelchair	0.631	0.369	0.000
W04 Fall while being carried or supported by other persons	0.631	0.369	0.000
W00 Fall on same level involving ice and snow	0.631	0.369	0.000
M89 Other disorders of bone	0.630	0.369	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.630	0.370	0.000
M65.34 Trigger finger-Hand	0.629	0.371	0.000
M80.8 Other osteoporosis with pathological fracture	0.628	0.372	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.628	0.372	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.628	0.372	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.628	0.372	0.000
H10-H13 Disorders of conjunctiva	0.628	0.372	0.000
T79.7 Traumatic subcutaneous emphysema	0.627	0.373	0.000
T78.3 Angioneurotic oedema	0.627	0.373	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.626	0.374	0.000
T17 Foreign body in respiratory tract	0.626	0.374	0.000
S72 Fracture of femur	0.625	0.375	0.000
W07.0 Home	0.625	0.375	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.625	0.375	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.624	0.376	0.000
M60 Myositis	0.624	0.376	0.000
E50-E64 Other nutritional deficiencies	0.623	0.377	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.622	0.378	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.622	0.378	0.000
K51.4 Pseudopolyposis of colon	0.000	0.378	0.622
V29 Motorcycle rider injured in other and unspecified transport accidents	0.620	0.380	0.000
V27 Motorcycle rider injured in collision with fixed or stationary object	0.620	0.380	0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.620	0.380	0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.620	0.380	0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.620	0.380	0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.620	0.380	0.000
V21 Motorcycle rider injured in collision with pedal cycle	0.620	0.380	0.000
V20 Motorcycle rider injured in collision with pedestrian or animal	0.620	0.380	0.000
S56 Injury of muscle and tendon at forearm level	0.620	0.380	0.000
J46 Status asthmaticus	0.619	0.381	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.619	0.381	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.619	0.381	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.619	0.381	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.619	0.381	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.619	0.381	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.619	0.381	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.619	0.381	0.000
H80-H83 Diseases of inner ear	0.618	0.382	0.000
H49 Paralytic strabismus	0.618	0.382	0.000
T74 Maltreatment syndromes	0.617	0.383	0.000
T73 Effects of other deprivation	0.617	0.383	0.000
T70 Effects of air pressure and water pressure	0.617	0.383	0.000
T69 Other effects of reduced temperature	0.617	0.383	0.000
T67 Effects of heat and light	0.617	0.383	0.000
T71 Asphyxiation	0.617	0.383	0.000
T66 Unspecified effects of radiation	0.617	0.383	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.617	0.383	0.000
G70-G73 Diseases of myoneural junction and muscle	0.616	0.384	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.616	0.384	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.616	0.384	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.615	0.385	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.615	0.385	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.615	0.385	0.000
T79.6 Traumatic ischaemia of muscle	0.615	0.385	0.000
H65.2 Chronic serous otitis media	0.615	0.385	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.614	0.386	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.614	0.386	0.000
Y48 Anaesthetics and therapeutic gases	0.614	0.386	0.000
M00.9 Pyogenic arthritis, unspecified	0.612	0.388	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.612	0.388	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.612	0.388	0.000
T18 Foreign body in alimentary tract	0.611	0.389	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.610	0.390	0.000
M34.0 Progressive systemic sclerosis	0.610	0.390	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.610	0.390	0.000
H65.4 Other chronic nonsuppurative otitis media	0.610	0.390	0.000
W22.9 Unspecified place	0.610	0.390	0.000
M30.0 Polyarteritis nodosa	0.609	0.390	0.000
W44 Foreign body entering into or through eye or natural orifice	0.609	0.391	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.609	0.391	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.609	0.391	0.000
M84.01 Malunion of fracture (Shoulder region)	0.608	0.392	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.608	0.392	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.606	0.394	0.000
M84.03 Malunion of fracture (Forearm)	0.606	0.394	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.605	0.395	0.000
S52.00 Fracture of upper end of ulna (closed)	0.604	0.396	0.000
H65.1 Other acute nonsuppurative otitis media	0.604	0.396	0.000
H65.0 Acute serous otitis media	0.604	0.396	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.603	0.397	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.398	0.602
M94 Other disorders of cartilage	0.602	0.398	0.000
S98 Traumatic amputation of ankle and foot	0.601	0.399	0.000
S97 Crushing injury of ankle and foot	0.601	0.399	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.601	0.399	0.000
S95 Injury of blood vessels at ankle and foot level	0.601	0.399	0.000
S94 Injury of nerves at ankle and foot level	0.601	0.399	0.000
W20 Struck by thrown, projected or falling object	0.601	0.399	0.000
S54.1 Injury of median nerve at forearm level	0.601	0.399	0.000
T78.2 Anaphylactic shock, unspecified	0.601	0.399	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.600	0.400	0.000
M67 Other disorders of synovium and tendon	0.599	0.401	0.000
S32.3 Fracture of ilium	0.599	0.401	0.000
T56 Toxic effect of metals	0.598	0.402	0.000
H05 Disorders of orbit	0.598	0.402	0.000
S79 Other and unspecified injuries of hip and thigh	0.598	0.402	0.000
M34.1 CR(E)ST syndrome	0.597	0.403	0.000
L73 Other follicular disorders	0.596	0.404	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.596	0.404	0.000
M84.04 Malunion of fracture (Hand)	0.596	0.404	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.595	0.405	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations