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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs416352
log Bayes Factor = 74.5968
Chromosome 6   position 32,207,393  (GRCh37) Explore rs416352 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
D64 Other anaemias
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
D64.9 Anaemia, unspecified
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
M15-M19 Arthrosis
0.999 0.001 0.000
N18.3 Chronic kidney disease, stage 3
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
N04 Nephrotic syndrome
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.002 0.998
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
D86 Sarcoidosis
0.997 0.003 0.000
M17.1 Other primary gonarthrosis
0.997 0.003 0.000
D50 Iron deficiency anaemia
0.997 0.003 0.000
M05 Seropositive rheumatoid arthritis
0.002 0.004 0.995
M05-M14 Inflammatory polyarthropathies
0.003 0.004 0.993
H30-H36 Disorders of choroid and retina
0.995 0.005 0.000
N04.9 Unspecified
0.995 0.005 0.000
N05 Unspecified nephritic syndrome
0.994 0.006 0.000
H36 Retinal disorders in diseases classified elsewhere
0.994 0.006 0.000
H36.0 Diabetic retinopathy
0.993 0.007 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.992 0.008 0.000
M18 Arthrosis of first carpometacarpal joint
0.992 0.008 0.000
E14.3 With ophthalmic complications
0.991 0.009 0.000
D50.9 Iron deficiency anaemia, unspecified
0.989 0.011 0.000
D86.9 Sarcoidosis, unspecified
0.989 0.011 0.000
N25-N29 Other disorders of kidney and ureter
0.989 0.011 0.000
E10.4 With neurological complications
0.986 0.014 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.985 0.015 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.983 0.017 0.000
N18.9 Chronic renal failure, unspecified
0.981 0.019 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.979 0.021 0.000
M06.3 Rheumatoid nodule
0.000 0.023 0.977
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.976 0.024 0.000
E83.1 Disorders of iron metabolism
0.000 0.025 0.975
N05.2 Diffuse membranous glomerulonephritis
0.972 0.028 0.000
M17.0 Primary gonarthrosis, bilateral
0.971 0.029 0.000
M35 Other systemic involvement of connective tissue
0.970 0.030 0.000
H06.2 Dysthyroid exophthalmos
0.964 0.036 0.000
N05.9 Unspecified
0.961 0.039 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.961 0.039 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.041 0.959
N17 Acute renal failure
0.958 0.042 0.000
H02 Other disorders of eyelid
0.957 0.043 0.000
H02.5 Other disorders affecting eyelid function
0.957 0.043 0.000
M35.0 Sicca syndrome [Sjogren]
0.957 0.043 0.000
M24 Other specific joint derangements
0.956 0.044 0.000
N18.2 Chronic kidney disease, stage 2
0.955 0.045 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.046 0.954
E10.2 With renal complications
0.949 0.051 0.000
E14.9 Without complications
0.945 0.055 0.000
N17.9 Acute renal failure, unspecified
0.945 0.055 0.000
E20-E35 Disorders of other endocrine glands
0.940 0.060 0.000
M33 Dermatopolymyositis
0.939 0.061 0.000
H00.1 Chalazion
0.000 0.064 0.936
M06.34 Rheumatoid nodule (Hand)
0.000 0.072 0.928
H34 Retinal vascular occlusions
0.923 0.077 0.000
D50.8 Other iron deficiency anaemias
0.921 0.079 0.000
E27 Other disorders of adrenal gland
0.916 0.084 0.000
E27.1 Primary adrenocortical insufficiency
0.913 0.087 0.000
E06 Thyroiditis
0.908 0.092 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.093 0.907
Chapter XX External causes of morbidity and mortality
0.907 0.093 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.094 0.906
D61 Other aplastic anaemias
0.902 0.098 0.000
N04.2 Diffuse membranous glomerulonephritis
0.900 0.100 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.900 0.100 0.000
E07 Other disorders of thyroid
0.898 0.102 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.102 0.898
K40 Inguinal hernia
0.000 0.104 0.896
N18.0 End-stage renal disease
0.895 0.105 0.000
D51 Vitamin B12 deficiency anaemia
0.894 0.106 0.000
D86.8 Sarcoidosis of other and combined sites
0.894 0.106 0.000
M60-M63 Disorders of muscles
0.889 0.111 0.000
E14.1 With ketoacidosis
0.888 0.112 0.000
M35.7 Hypermobility syndrome
0.885 0.115 0.000
H34.8 Other retinal vascular occlusions
0.877 0.123 0.000
M33.2 Polymyositis
0.877 0.123 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.125 0.875
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.875 0.125 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.873 0.127 0.000
D86.0 Sarcoidosis of lung
0.869 0.131 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.868 0.132 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.863 0.137 0.000
H00 Hordeolum and chalazion
0.088 0.137 0.775
N03 Chronic nephritic syndrome
0.863 0.137 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.861 0.139 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.859 0.141 0.000
V20-V29 Motorcycle rider injured in transport accident
0.856 0.144 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.148 0.852
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.852 0.148 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.851 0.149 0.000
Y42.7 Androgens and anabolic congeners
0.851 0.149 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.842 0.158 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.159 0.841
D61.9 Aplastic anaemia, unspecified
0.838 0.162 0.000
M32 Systemic lupus erythematosus
0.836 0.164 0.000
H02.6 Xanthelasma of eyelid
0.835 0.165 0.000
E14.8 With unspecified complications
0.835 0.165 0.000
M91-M94 Chondropathies
0.829 0.171 0.000
N18.4 Chronic kidney disease, stage 4
0.828 0.172 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.826 0.174 0.000
M60 Myositis
0.823 0.177 0.000
Y43 Primarily systemic agents
0.823 0.177 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.823 0.177 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.184 0.816
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.814 0.186 0.000
E14.4 With neurological complications
0.811 0.189 0.000
H05 Disorders of orbit
0.811 0.189 0.000
H02.0 Entropion and trichiasis of eyelid
0.808 0.192 0.000
V23.4 Driver injured in traffic accident
0.806 0.194 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.194 0.806
N04.1 Focal and segmental glomerular lesions
0.803 0.197 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.803 0.197 0.000
M80-M85 Disorders of bone density and structure
0.802 0.198 0.000
Y43.3 Other antineoplastic drugs
0.801 0.199 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.800 0.200 0.000
D83 Common variable immunodeficiency
0.798 0.202 0.000
E10.0 With coma
0.797 0.203 0.000
M23 Internal derangement of knee
0.794 0.206 0.000
X20-X29 Contact with venomous animals and plants
0.790 0.210 0.000
M14 Arthropathies in other diseases classified elsewhere
0.002 0.212 0.787
M18.1 Other primary arthrosis of first carpometacarpal joint
0.786 0.214 0.000
E07.8 Other specified disorders of thyroid
0.786 0.214 0.000
M35.1 Other overlap syndromes
0.782 0.218 0.000
E24 Cushing's syndrome
0.780 0.220 0.000
D86.3 Sarcoidosis of skin
0.779 0.221 0.000
M33.1 Other dermatomyositis
0.778 0.222 0.000
M86-M90 Other osteopathies
0.777 0.223 0.000
W20-W49 Exposure to inanimate mechanical forces
0.777 0.223 0.000
H02.1 Ectropion of eyelid
0.776 0.224 0.000
Y48 Anaesthetics and therapeutic gases
0.773 0.227 0.000
D86.1 Sarcoidosis of lymph nodes
0.772 0.228 0.000
E10.5 With peripheral circulatory complications
0.772 0.228 0.000
E10.7 With multiple complications
0.769 0.231 0.000
M24.7 Protrusio acetabuli
0.768 0.232 0.000
N18.1 Chronic kidney disease, stage 1
0.767 0.233 0.000
M24.1 Other articular cartilage disorders
0.767 0.233 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.234 0.766
M24.9 Joint derangement, unspecified
0.763 0.237 0.000
H46 Optic neuritis
0.762 0.238 0.000
E29 Testicular dysfunction
0.760 0.240 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.760 0.240 0.000
N25 Disorders resulting from impaired renal tubular function
0.759 0.241 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.757 0.242 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.757 0.243 0.000
E06.9 Thyroiditis, unspecified
0.753 0.247 0.000
M60.9 Myositis, unspecified
0.753 0.247 0.000
H30 Chorioretinal inflammation
0.752 0.248 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.752 0.248 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.751 0.249 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.750 0.250 0.000
M15 Polyarthrosis
0.749 0.251 0.000
D50.1 Sideropenic dysphagia
0.747 0.252 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.747 0.253 0.000
N02 Recurrent and persistent haematuria
0.747 0.253 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.746 0.254 0.000
E13 Other specified diabetes mellitus
0.745 0.255 0.000
N05.1 Focal and segmental glomerular lesions
0.743 0.257 0.000
E16.1 Other hypoglycaemia
0.742 0.258 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.742 0.258 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.259 0.741
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.259 0.741
V80-V89 Other land transport accidents
0.739 0.261 0.000
E14.2 Withrenal complications
0.738 0.262 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.738 0.262 0.000
E06.1 Subacute thyroiditis
0.736 0.264 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.735 0.265 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.735 0.265 0.000
E07.9 Disorder of thyroid, unspecified
0.734 0.266 0.000
N00 Acute nephritic syndrome
0.734 0.266 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.018 0.268 0.714
D64.8 Other specified anaemias
0.732 0.268 0.000
D82 Immunodeficiency associated with other major defects
0.731 0.268 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.269 0.731
D51.3 Other dietary vitamin B12 deficiency anaemia
0.730 0.270 0.000
M23.0 Cystic meniscus
0.729 0.271 0.000
D52 Folate deficiency anaemia
0.728 0.272 0.000
E31 Polyglandular dysfunction
0.726 0.274 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.274 0.726
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.275 0.725
Y42.2 Antithyroid drugs
0.722 0.278 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.279 0.721
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.721 0.279 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.720 0.280 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.719 0.281 0.000
M82 Osteoporosis in diseases classified elsewhere
0.719 0.281 0.000
N03.1 Focal and segmental glomerular lesions
0.719 0.281 0.000
M94 Other disorders of cartilage
0.719 0.281 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.716
M06.2 Rheumatoid bursitis
0.000 0.283 0.716
M06.1 Adult-onset Still's disease
0.000 0.283 0.716
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
N04.8 Other
0.716 0.284 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.716 0.284 0.000
N04.6 Dense deposit disease
0.716 0.284 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.716 0.284 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.716 0.284 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.716 0.284 0.000
N04.0 Minor glomerular abnormality
0.716 0.284 0.000
E06.3 Autoimmune thyroiditis
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
D81 Combined immunodeficiencies
0.716 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.716 0.284 0.000
D53 Other nutritional anaemias
0.715 0.285 0.000
N02.2 Diffuse membranous glomerulonephritis
0.714 0.286 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.286 0.713
M05.1 Rheumatoid lung disease
0.001 0.286 0.713
M05.0 Felty's syndrome
0.001 0.286 0.713
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.286 0.712
M08 Juvenile arthritis
0.002 0.286 0.712
Y57 Other and unspecified drugs and medicaments
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
N05.6 Dense deposit disease
0.713 0.287 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.713 0.287 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.713 0.287 0.000
N05.0 Minor glomerular abnormality
0.713 0.287 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.712 0.288 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.712 0.288 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.711 0.289 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.711 0.289 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.711 0.289 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
X23 Contact with hornets, wasps and bees
0.706 0.294 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.703 0.297 0.000
E24.2 Drug-induced Cushing's syndrome
0.702 0.298 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.299 0.701
M06.38 Rheumatoid nodule (Other)
0.000 0.299 0.701
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.299 0.701
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.299 0.701
M06.33 Rheumatoid nodule (Forearm)
0.000 0.299 0.701
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.299 0.701
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.700 0.300 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.700 0.300 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.700 0.300 0.000
N18.5 Chronic kidney disease, stage 5
0.700 0.300 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.699 0.301 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.699 0.301 0.000
M86 Osteomyelitis
0.699 0.301 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.302 0.697
E22 Hyperfunction of pituitary gland
0.698 0.302 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.698 0.302 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.302 0.697
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.304 0.696
M35.9 Systemic involvement of connective tissue, unspecified
0.696 0.304 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.696 0.304 0.000
M35.5 Multifocal fibrosclerosis
0.696 0.304 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.696 0.304 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.694 0.306 0.000
E06.5 Other chronic thyroiditis
0.692 0.308 0.000
E28 Ovarian dysfunction
0.691 0.309 0.000
H10-H13 Disorders of conjunctiva
0.690 0.310 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.310 0.000
H34.9 Retinal vascular occlusion, unspecified
0.689 0.311 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.689 0.311 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.689 0.311 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.689 0.311 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.689 0.311 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.689 0.311 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.689 0.311 0.000
N17.2 Acute renal failure with medullary necrosis
0.687 0.313 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.686 0.314 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.684 0.316 0.000
H05.8 Other disorders of orbit
0.683 0.317 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.682 0.318 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.682 0.318 0.000
M24.6 Ankylosis of joint
0.682 0.318 0.000
M24.5 Contracture of joint
0.682 0.318 0.000
N03.8 Other
0.681 0.319 0.000
M25 Other joint disorders, not elsewhere classified
0.679 0.321 0.000
H50 Other strabismus
0.678 0.322 0.000
M60.99 Myositis, unspecified (Site unspecified)
0.677 0.323 0.000
M34 Systemic sclerosis
0.676 0.324 0.000
M22 Disorders of patella
0.676 0.324 0.000
M12 Other specific arthropathies
0.002 0.325 0.673
E35 Disorders of endocrine glands in diseases classified elsewhere
0.674 0.326 0.000
E32 Diseases of thymus
0.674 0.326 0.000
E30 Disorders of puberty, not elsewhere classified
0.674 0.326 0.000
N18.8 Other chronic renal failure
0.674 0.326 0.000
M33.9 Dermatopolymyositis, unspecified
0.673 0.326 0.000
M33.0 Juvenile dermatomyositis
0.673 0.326 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.673 0.327 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.673 0.327 0.000
W45 Foreign body or object entering through skin
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.666 0.333 0.000
N27 Small kidney of unknown cause
0.666 0.334 0.000
E14.5 With peripheral circulatory complications
0.665 0.335 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.665 0.335 0.000
M80 Osteoporosis with pathological fracture
0.665 0.335 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
Y48.2 Other and unspecified general anaesthetics
0.663 0.337 0.000
H34.0 Transient retinal artery occlusion
0.662 0.338 0.000
M35.2 Behcet's disease
0.662 0.338 0.000
Y48.3 Local anaesthetics
0.661 0.339 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.660 0.340 0.000
M82.1 Osteoporosis in endocrine disorders
0.660 0.340 0.000
Y54.5 Other diuretics
0.659 0.341 0.000
M93 Other osteochondropathies
0.658 0.342 0.000
M17.5 Other secondary gonarthrosis
0.658 0.342 0.000
E27.5 Adrenomedullary hyperfunction
0.657 0.343 0.000
E27.0 Other adrenocortical overactivity
0.657 0.343 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.656 0.344 0.000
M23.3 Other meniscus derangements
0.656 0.344 0.000
N03.9 Unspecified
0.656 0.344 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.655 0.345 0.000
D83.9 Common variable immunodeficiency, unspecified
0.655 0.345 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
M05.2 Rheumatoid vasculitis
0.001 0.347 0.652
X23.9 Unspecified place
0.653 0.347 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.652 0.348 0.000
E10.8 With unspecified complications
0.651 0.348 0.000
E06.4 Drug-induced thyroiditis
0.651 0.349 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.651 0.349 0.000
E06.0 Acute thyroiditis
0.651 0.349 0.000
Y35-Y36 Legal intervention and operations of war
0.650 0.350 0.000
X85-X99 Assault
0.650 0.350 0.000
X30-X39 Exposure to forces of nature
0.650 0.350 0.000
W65-W74 Accidental drowning and submersion
0.650 0.350 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.650 0.350 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.650 0.350 0.000
H34.2 Other retinal artery occlusions
0.650 0.350 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.351 0.649
N19 Unspecified renal failure
0.649 0.351 0.000
Y44 Agents primarily affecting blood constituents
0.649 0.351 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.649 0.351 0.000
Y42.9 Other and unspecified hormone antagonists
0.648 0.352 0.000
D61.8 Other specified aplastic anaemias
0.646 0.353 0.000
D61.3 Idiopathic aplastic anaemia
0.646 0.353 0.000
D61.2 Aplastic anaemia due to other external agents
0.646 0.353 0.000
Y10-Y34 Event of undetermined intent
0.646 0.354 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.645 0.355 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.645 0.355 0.000
E03.8 Other specified hypothyroidism
0.645 0.355 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.645 0.355 0.000
E03.1 Congenital hypothyroidism without goitre
0.644 0.356 0.000
E07.1 Dyshormogenetic goitre
0.644 0.356 0.000
E07.0 Hypersecretion of calcitonin
0.644 0.356 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.644 0.356 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.643 0.357 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.358 0.642
W49 Exposure to other and unspecified inanimate mechanical forces
0.641 0.359 0.000
D51.2 Transcobalamin II deficiency
0.641 0.359 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.641 0.359 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.641 0.359 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.639 0.361 0.000
M83 Adult osteomalacia
0.639 0.361 0.000
D61.1 Drug-induced aplastic anaemia
0.638 0.362 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.637 0.363 0.000
M61 Calcification and ossification of muscle
0.637 0.363 0.000
M25.9 Joint disorder, unspecified
0.637 0.363 0.000
D55-D59 Haemolytic anaemias
0.636 0.364 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.636 0.364 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.636 0.364 0.000
M00-M03 Infectious arthropathies
0.635 0.364 0.000
W34 Discharge from other and unspecified firearms
0.635 0.365 0.000
M14.6 Neuropathic arthropathy
0.001 0.365 0.634
M24.2 Disorder of ligament
0.635 0.365 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.634 0.366 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.366 0.633
E29.1 Testicular hypofunction
0.631 0.369 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.631 0.369 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.630 0.370 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.630 0.370 0.000
X00-X09 Exposure to smoke, fire and flames
0.629 0.371 0.000
M21 Other acquired deformities of limbs
0.629 0.371 0.000
D61.0 Constitutional aplastic anaemia
0.629 0.371 0.000
H49 Paralytic strabismus
0.627 0.373 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.626 0.374 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.374 0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.625 0.375 0.000
W87 Exposure to unspecified electric current
0.625 0.375 0.000
Q50-Q56 Congenital malformations of genital organs
0.624 0.376 0.000
M94.2 Chondromalacia
0.624 0.376 0.000
W40 Explosion of other materials
0.623 0.377 0.000
E11 Non-insulin-dependent diabetes mellitus
0.623 0.377 0.000
H05.1 Chronic inflammatory disorders of orbit
0.622 0.378 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.622 0.378 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.622 0.378 0.000
V95-V97 Air and space transport accidents
0.621 0.378 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.379 0.621
Y43.0 Antiallergic and antiemetic drugs
0.620 0.380 0.000
Y65 Other misadventures during surgical and medical care
0.620 0.380 0.000
H35 Other retinal disorders
0.619 0.381 0.000
M23.4 Loose body in knee
0.619 0.381 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.619 0.381 0.000
N03.6 Dense deposit disease
0.619 0.381 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.619 0.381 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.619 0.381 0.000
N03.2 Diffuse membranous glomerulonephritis
0.619 0.381 0.000
N03.0 Minor glomerular abnormality
0.619 0.381 0.000
H05.2 Exophthalmic conditions
0.616 0.384 0.000
M11 Other crystal arthropathies
0.002 0.384 0.614
E65-E68 Obesity and other hyperalimentation
0.615 0.385 0.000
H34.1 Central retinal artery occlusion
0.614 0.385 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.614 0.386 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.614 0.386 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.614 0.386 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.614 0.386 0.000
W75-W84 Other accidental threats to breathing
0.613 0.386 0.000
V70-V79 Bus occupant injured in transport accident
0.612 0.388 0.000
Y42.4 Oral contraceptives
0.611 0.389 0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)
0.611 0.389 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.611 0.389 0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.610 0.390 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.608 0.392 0.000
D80 Immunodeficiency with predominantly antibody defects
0.606 0.394 0.000
Y53.4 Other laxatives
0.605 0.395 0.000
Y59 Other and unspecified vaccines and biological substances
0.605 0.395 0.000
W21 Striking against or struck by sports equipment
0.604 0.396 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.604 0.396 0.000
D69 Purpura and other haemorrhagic conditions
0.603 0.397 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.603 0.397 0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere
0.602 0.398 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.601 0.399 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.601 0.399 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.599 0.401 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.599 0.401 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.599 0.401 0.000
Y58 Bacterial vaccines
0.598 0.402 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.598 0.402 0.000
H50.5 Heterophoria
0.596 0.404 0.000
H02.2 Lagophthalmos
0.595 0.404 0.000
N25.1 Nephrogenic diabetes insipidus
0.595 0.405 0.000
E10.6 With other specified complications
0.595 0.405 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.405 0.595
N05.8 Other
0.595 0.405 0.000
W27 Contact with nonpowered hand tool
0.594 0.406 0.000
E50-E64 Other nutritional deficiencies
0.594 0.406 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.593 0.407 0.000
X50-X57 Overexertion, travel and privation
0.593 0.407 0.000
W49.0 Home
0.593 0.407 0.000
V98-V99 Other and unspecified transport accidents
0.593 0.407 0.000
V23.9 Unspecified motorcycle rider injured in traffic accident
0.592 0.408 0.000
V23.3 Person injured while boarding or alighting
0.592 0.408 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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