TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs439303
log Bayes Factor = 47.0495
Chromosome 6   position 32,208,921  (GRCh37) Explore rs439303 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.999 0.001 0.000
L40 Psoriasis
0.999 0.001 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.001 0.999
D86 Sarcoidosis
0.000 0.001 0.999
D50-D53 Nutritional anaemias
0.000 0.002 0.998
J33 Nasal polyp
0.000 0.002 0.998
D50 Iron deficiency anaemia
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.002 0.998
D80-D89 Certain disorders involving the immune mechanism
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.005 0.995
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.019 0.981
D50.8 Other iron deficiency anaemias
0.000 0.022 0.978
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.973 0.027 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.030 0.970
E10.3 With ophthalmic complications
0.000 0.033 0.967
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.045 0.955
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.955 0.045 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.056 0.944
K51 Ulcerative colitis
0.000 0.058 0.942
E27 Other disorders of adrenal gland
0.000 0.058 0.942
E20-E35 Disorders of other endocrine glands
0.000 0.059 0.941
D50.9 Iron deficiency anaemia, unspecified
0.000 0.065 0.935
E10.1 With ketoacidosis
0.000 0.066 0.934
J33.8 Other polyp of sinus
0.000 0.082 0.918
E07 Other disorders of thyroid
0.000 0.084 0.916
E06 Thyroiditis
0.000 0.096 0.904
K90 Intestinal malabsorption
0.000 0.096 0.904
D86.1 Sarcoidosis of lymph nodes
0.000 0.101 0.899
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.108 0.892
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.109 0.891
D51 Vitamin B12 deficiency anaemia
0.000 0.114 0.886
C82.0 Small cleaved cell, follicular
0.884 0.116 0.000
D68 Other coagulation defects
0.000 0.117 0.883
K51.8 Other ulcerative colitis
0.000 0.121 0.879
E50-E64 Other nutritional deficiencies
0.000 0.124 0.876
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.872 0.128 0.000
E10.2 With renal complications
0.000 0.134 0.866
D86.0 Sarcoidosis of lung
0.000 0.146 0.854
L40-L45 Papulosquamous disorders
0.813 0.151 0.035
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.156 0.844
C82.1 Mixed small cleaved and large cell, follicular
0.839 0.161 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.170 0.830
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.180 0.820
K90.9 Intestinal malabsorption, unspecified
0.000 0.186 0.814
E06.3 Autoimmune thyroiditis
0.000 0.191 0.809
C82.3 Follicular lymphoma grade IIIa
0.806 0.194 0.000
K51.5 Mucosal proctocolitis
0.000 0.200 0.800
E14 Unspecified diabetes mellitus
0.000 0.201 0.799
D86.8 Sarcoidosis of other and combined sites
0.000 0.207 0.793
J30-J39 Other diseases of upper respiratory tract
0.000 0.210 0.790
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.211 0.789
D60-D64 Aplastic and other anaemias
0.000 0.212 0.788
L40.4 Guttate psoriasis
0.778 0.222 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.223 0.777
D53 Other nutritional anaemias
0.000 0.227 0.773
D66 Hereditary factor VIII deficiency
0.000 0.229 0.771
E55 Vitamin D deficiency
0.000 0.229 0.770
D64 Other anaemias
0.000 0.230 0.770
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.233 0.767
E14.3 With ophthalmic complications
0.000 0.235 0.765
C82.2 Large cell, follicular
0.762 0.238 0.000
E10.5 With peripheral circulatory complications
0.000 0.240 0.760
E10.0 With coma
0.000 0.241 0.759
T50.9 Other and unspecified drugs, medicaments and biological substances
0.755 0.245 0.000
E10.4 With neurological complications
0.000 0.246 0.754
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.247 0.753
D68.5 Primary Thrombophilia
0.000 0.248 0.752
J34 Other disorders of nose and nasal sinuses
0.000 0.249 0.751
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.251 0.749
D52 Folate deficiency anaemia
0.000 0.258 0.742
E06.9 Thyroiditis, unspecified
0.000 0.258 0.741
D68.8 Other specified coagulation defects
0.000 0.260 0.740
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.739 0.261 0.000
D68.2 Hereditary deficiency of other clotting factors
0.000 0.261 0.739
E07.8 Other specified disorders of thyroid
0.000 0.263 0.737
L43 Lichen planus
0.722 0.264 0.014
D64.9 Anaemia, unspecified
0.000 0.264 0.736
D68.0 Von Willebrand's disease
0.000 0.272 0.728
E53 Deficiency of other B group vitamins
0.000 0.273 0.727
T36-T50 Poisoning by drugs, medicaments and biological substances
0.727 0.273 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.278 0.722
J34.3 Hypertrophy of nasal turbinates
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.716 0.284 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.284 0.716
J33.1 Polypoid sinus degeneration
0.000 0.284 0.716
D50.1 Sideropenic dysphagia
0.000 0.284 0.716
D82 Immunodeficiency associated with other major defects
0.000 0.285 0.715
D81 Combined immunodeficiencies
0.000 0.285 0.715
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.712 0.288 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.294 0.706
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.701 0.299 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.305 0.695
D83 Common variable immunodeficiency
0.000 0.311 0.689
L40.3 Pustulosis palmaris et plantaris
0.688 0.312 0.000
D67 Hereditary factor IX deficiency
0.000 0.315 0.685
C82.6 Cutaneous follicle centre lymphoma
0.685 0.315 0.000
C82.5 Diffuse follicle centre lymphoma
0.685 0.315 0.000
C82.4 Follicular lymphoma grade IIIb
0.685 0.315 0.000
D64.8 Other specified anaemias
0.000 0.315 0.685
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.684 0.316 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.317 0.683
L40.1 Generalised pustular psoriasis
0.682 0.318 0.000
K90-K93 Other diseases of the digestive system
0.000 0.320 0.680
# Top node
0.000 0.320 0.680
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.321 0.679
Chapter X Diseases of the respiratory system
0.000 0.322 0.678
E27.2 Addisonian crisis
0.000 0.323 0.677
E27.5 Adrenomedullary hyperfunction
0.000 0.324 0.675
E27.0 Other adrenocortical overactivity
0.000 0.324 0.675
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.325 0.675
E32 Diseases of thymus
0.000 0.325 0.675
E31 Polyglandular dysfunction
0.000 0.325 0.675
E30 Disorders of puberty, not elsewhere classified
0.000 0.325 0.675
E65-E68 Obesity and other hyperalimentation
0.000 0.329 0.671
J34.2 Deviated nasal septum
0.000 0.330 0.670
E20 Hypoparathyroidism
0.000 0.331 0.669
E34 Other endocrine disorders
0.000 0.336 0.664
Chapter XI Diseases of the digestive system
0.000 0.336 0.664
E29 Testicular dysfunction
0.000 0.339 0.660
E07.1 Dyshormogenetic goitre
0.000 0.343 0.657
E07.0 Hypersecretion of calcitonin
0.000 0.343 0.657
L43.9 Lichen planus, unspecified
0.656 0.343 0.001
L42 Pityriasis rosea
0.635 0.345 0.020
T46 Poisoning by agents primarily affecting the cardiovascular system
0.651 0.349 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.650 0.350 0.000
E28 Ovarian dysfunction
0.000 0.350 0.650
L44 Other papulosquamous disorders
0.626 0.351 0.023
D68.1 Hereditary factor XI deficiency
0.000 0.351 0.649
E05.8 Other thyrotoxicosis
0.000 0.352 0.648
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.648 0.352 0.000
L20-L30 Dermatitis and eczema
0.000 0.352 0.648
E06.4 Drug-induced thyroiditis
0.000 0.352 0.648
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.352 0.648
E06.1 Subacute thyroiditis
0.000 0.352 0.648
E06.0 Acute thyroiditis
0.000 0.352 0.648
K90.3 Pancreatic steatorrhoea
0.000 0.352 0.648
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.352 0.648
K90.1 Tropical sprue
0.000 0.352 0.648
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.356 0.644
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.365 0.635
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.365 0.635
D51.2 Transcobalamin II deficiency
0.000 0.365 0.635
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.365 0.635
E10.6 With other specified complications
0.000 0.366 0.634
D68.4 Acquired coagulation factor deficiency
0.000 0.367 0.633
Chapter VI Diseases of the nervous system
0.000 0.370 0.630
L30 Other dermatitis
0.000 0.370 0.630
E51 Thiamine deficiency
0.000 0.371 0.629
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.372 0.628
E63 Other nutritional deficiencies
0.000 0.372 0.628
E56 Other vitamin deficiencies
0.000 0.372 0.628
E50 Vitamin A deficiency
0.000 0.372 0.628
E60 Dietary zinc deficiency
0.000 0.372 0.628
E59 Dietary selenium deficiency
0.000 0.372 0.628
E54 Ascorbic acid deficiency
0.000 0.372 0.628
E52 Niacin deficiency [pellagra]
0.000 0.372 0.628
L27 Dermatitis due to substances taken internally
0.000 0.374 0.626
L30.9 Dermatitis, unspecified
0.000 0.376 0.624
Chapter XII Diseases of the skin and subcutaneous tissue
0.001 0.376 0.623
E58 Dietary calcium deficiency
0.000 0.383 0.616
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.384 0.615
D53.9 Nutritional anaemia, unspecified
0.000 0.389 0.611
J34.1 Cyst and mucocele of nose and nasal sinus
0.000 0.389 0.611
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.390 0.610
L41 Parapsoriasis
0.583 0.391 0.025
L45 Papulosquamous disorders in diseases classified elsewhere
0.583 0.391 0.025
E06.5 Other chronic thyroiditis
0.000 0.392 0.608
D84 Other immunodeficiencies
0.000 0.399 0.601
T42.3 Barbiturates
0.600 0.400 0.000
L43.0 Hypertrophic lichen planus
0.591 0.401 0.008
J31.2 Chronic pharyngitis
0.000 0.403 0.597
L29 Pruritus
0.000 0.405 0.595
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.405 0.594
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.408 0.592
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.588 0.412 0.000
E14.1 With ketoacidosis
0.000 0.415 0.585
K90.8 Other intestinal malabsorption
0.000 0.415 0.585
E14.4 With neurological complications
0.000 0.415 0.585
E53.8 Deficiency of other specified B group vitamins
0.000 0.417 0.583
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.420 0.580
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.420 0.580
J84 Other interstitial pulmonary diseases
0.000 0.421 0.579
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.579 0.421 0.000
J35 Chronic diseases of tonsils and adenoids
0.000 0.423 0.577
E16 Other disorders of pancreatic internal secretion
0.000 0.424 0.576
L29.0 Pruritus ani
0.000 0.424 0.576
E53.9 Vitamin B deficiency, unspecified
0.000 0.424 0.576
J20-J22 Other acute lower respiratory infections
0.000 0.424 0.576
E14.2 Withrenal complications
0.000 0.426 0.573
E14.7 With multiple complications
0.000 0.427 0.573
E14.0 With coma
0.000 0.427 0.573
L40.8 Other psoriasis
0.572 0.428 0.000
D86.3 Sarcoidosis of skin
0.000 0.430 0.569
J39 Other diseases of upper respiratory tract
0.000 0.434 0.566
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.435 0.565
E24 Cushing's syndrome
0.000 0.436 0.563
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.563 0.437 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.561 0.439 0.000
L40.0 Psoriasis vulgaris
0.560 0.440 0.000
J35.0 Chronic tonsillitis
0.000 0.441 0.559
G36 Other acute disseminated demyelination
0.000 0.441 0.559
D52.9 Folate deficiency anaemia, unspecified
0.000 0.441 0.559
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.444 0.556
D53.8 Other specified nutritional anaemias
0.000 0.446 0.554
D53.2 Scorbutic anaemia
0.000 0.446 0.554
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.446 0.554
D53.0 Protein deficiency anaemia
0.000 0.446 0.554
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.553 0.447 0.000
E55.0 Rickets, active
0.000 0.447 0.552
D55-D59 Haemolytic anaemias
0.000 0.448 0.552
E14.8 With unspecified complications
0.000 0.448 0.552
D64.4 Congenital dyserythropoietic anaemia
0.000 0.448 0.552
D64.3 Other sideroblastic anaemias
0.000 0.448 0.552
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.448 0.552
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.448 0.552
D64.0 Hereditary sideroblastic anaemia
0.000 0.448 0.552
E25 Adrenogenital disorders
0.000 0.448 0.551
E22 Hyperfunction of pituitary gland
0.000 0.451 0.549
T50.4 Drugs affecting uric acid metabolism
0.549 0.451 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.451 0.549
E34.0 Carcinoid syndrome
0.000 0.453 0.547
T50.6 Antidotes and chelating agents, not elsewhere classified
0.546 0.454 0.000
E28.3 Primary ovarian failure
0.000 0.459 0.541
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.459 0.541
E61 Deficiency of other nutrient elements
0.000 0.460 0.540
E15 Nondiabetic hypoglycaemic coma
0.000 0.460 0.540
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.466 0.534
G37 Other demyelinating diseases of central nervous system
0.000 0.467 0.533
D52.8 Other folate deficiency anaemias
0.000 0.468 0.532
D52.1 Drug-induced folate deficiency anaemia
0.000 0.468 0.532
D52.0 Dietary folate deficiency anaemia
0.000 0.468 0.532
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.469 0.531
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.530 0.470 0.000
T50.7 Analeptics and opioid receptor antagonists
0.530 0.470 0.000
T50.5 Appetite depressants
0.530 0.470 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.530 0.470 0.000
T50.1 Loop [high-ceiling] diuretics
0.530 0.470 0.000
T50.0 Mineralocorticoids and their antagonists
0.530 0.470 0.000
J37 Chronic laryngitis and laryngotracheitis
0.000 0.472 0.528
J32 Chronic sinusitis
0.000 0.472 0.528
L43.3 Subacute (active) lichen planus
0.518 0.472 0.010
L43.2 Lichenoid drug reaction
0.518 0.472 0.010
L43.1 Bullous lichen planus
0.518 0.472 0.010
J20 Acute bronchitis
0.000 0.473 0.527
L29.2 Pruritus vulvae
0.000 0.476 0.524
E53.1 Pyridoxine deficiency
0.000 0.478 0.522
E53.0 Riboflavin deficiency
0.000 0.478 0.522
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.521 0.479 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.521 0.479 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.521 0.479 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.520 0.480 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.518 0.482 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.484 0.516
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
L20 Atopic dermatitis
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
T42.4 Benzodiazepines
0.514 0.486 0.000
E14.6 With other specified complications
0.000 0.487 0.513
D81.9 Combined immunodeficiency, unspecified
0.000 0.487 0.513
D81.8 Other combined immunodeficiencies
0.000 0.487 0.513
D81.7 Major histocompatibility complex class II deficiency
0.000 0.487 0.513
D81.6 Major histocompatibility complex class I deficiency
0.000 0.487 0.513
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.487 0.513
D81.4 Nezelof's syndrome
0.000 0.487 0.513
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.487 0.513
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.487 0.513
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.487 0.513
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.487 0.513
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.487 0.513
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.487 0.513
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.487 0.513
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.487 0.513
D82.2 Immunodeficiency with short-limbed stature
0.000 0.487 0.513
D82.1 Di George's syndrome
0.000 0.487 0.513
D82.0 Wiskott-Aldrich syndrome
0.000 0.487 0.513
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.511 0.489 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.511 0.489 0.000
T42.2 Succinimides and oxazolidinediones
0.511 0.489 0.000
T45.0 Antiallergic and antiemetic drugs
0.511 0.489 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.509 0.491 0.000
E40-E46 Malnutrition
0.000 0.491 0.508
G90-G99 Other disorders of the nervous system
0.000 0.492 0.508
E65 Localised adiposity
0.000 0.492 0.508
T38.1 Thyroid hormones and substitutes
0.507 0.493 0.000
L21 Seborrhoeic dermatitis
0.000 0.493 0.507
L44.0 Pityriasis rubra pilaris
0.492 0.494 0.015
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.494 0.506
D89.3 Immune reconstitution syndrome
0.000 0.494 0.506
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.495 0.505
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.505 0.495 0.000
E13 Other specified diabetes mellitus
0.000 0.495 0.505
E14.5 With peripheral circulatory complications
0.000 0.495 0.504
E03.8 Other specified hypothyroidism
0.000 0.498 0.502
L25 Unspecified contact dermatitis
0.000 0.500 0.500
L27.2 Dermatitis due to ingested food
0.000 0.500 0.500
J31.1 Chronic nasopharyngitis
0.000 0.500 0.499
E26 Hyperaldosteronism
0.000 0.501 0.498
D68.6 Other Thrombophilia
0.000 0.503 0.497
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.496 0.503 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.506 0.494
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.506 0.494
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.506 0.494
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.506 0.494
L10-L14 Bullous disorders
0.000 0.509 0.491
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.490 0.509 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.490 0.509 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.490 0.509 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.490 0.509 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.490 0.509 0.000
T44.0 Anticholinesterase agents
0.490 0.509 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.512 0.488
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.512 0.488
E27.9 Disorder of adrenal gland, unspecified
0.000 0.516 0.484
T38.8 Other and unspecified hormones and their synthetic substitutes
0.484 0.516 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.516 0.484
E30.8 Other disorders of puberty
0.000 0.516 0.484
E30.1 Precocious puberty
0.000 0.516 0.484
E30.0 Delayed puberty
0.000 0.516 0.484
E31.9 Polyglandular dysfunction, unspecified
0.000 0.516 0.484
E31.8 Other polyglandular dysfunction
0.000 0.516 0.484
E31.1 Polyglandular hyperfunction
0.000 0.516 0.484
E31.0 Autoimmune polyglandular failure
0.000 0.516 0.484
E32.9 Disease of thymus, unspecified
0.000 0.516 0.484
E32.8 Other diseases of thymus
0.000 0.516 0.484
E32.1 Abscess of thymus
0.000 0.516 0.484
E32.0 Persistent hyperplasia of thymus
0.000 0.516 0.484
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.516 0.484
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.516 0.484
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.516 0.484
G30-G32 Other degenerative diseases of the nervous system
0.000 0.517 0.483
T50.8 Diagnostic agents
0.482 0.518 0.000
T36 Poisoning by systemic antibiotics
0.481 0.519 0.000
E67 Other hyperalimentation
0.000 0.519 0.481
E68 Sequelae of hyperalimentation
0.000 0.519 0.481
E10.8 With unspecified complications
0.001 0.520 0.479
G91 Hydrocephalus
0.000 0.520 0.480
E20.8 Other hypoparathyroidism
0.000 0.520 0.479
E20.1 Pseudohypoparathyroidism
0.000 0.520 0.479
E20.0 Idiopathic hypoparathyroidism
0.000 0.520 0.479
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.521 0.479
E34.5 Androgen resistance syndrome
0.000 0.524 0.476
E34.4 Constitutional tall stature
0.000 0.524 0.476
E34.3 Short stature, not elsewhere classified
0.000 0.524 0.476
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.524 0.476
E34.1 Other hypersecretion of intestinal hormones
0.000 0.524 0.476
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.476 0.524 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.526 0.474
E29.8 Other testicular dysfunction
0.000 0.526 0.474
E29.0 Testicular hyperfunction
0.000 0.526 0.474
E20.9 Hypoparathyroidism, unspecified
0.000 0.526 0.473
T47.1 Other antacids and anti-gastric-secretion drugs
0.469 0.531 0.000
D83.9 Common variable immunodeficiency, unspecified
0.000 0.531 0.468
J20.9 Acute bronchitis, unspecified
0.000 0.533 0.467
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.467 0.533 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.467 0.533 0.000
T46.7 Peripheral vasodilators
0.467 0.533 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.467 0.533 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.467 0.533 0.000
D89.1 Cryoglobulinaemia
0.000 0.533 0.466
E28.9 Ovarian dysfunction, unspecified
0.000 0.534 0.466
E28.8 Other ovarian dysfunction
0.000 0.534 0.466
E28.1 Androgen excess
0.000 0.534 0.466
E28.0 Oestrogen excess
0.000 0.534 0.466
L44.9 Papulosquamous disorder, unspecified
0.449 0.534 0.017
L44.8 Other specified papulosquamous disorders
0.449 0.534 0.017
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.449 0.534 0.017
L44.3 Lichen ruber moniliformis
0.449 0.534 0.017
L44.2 Lichen striatus
0.449 0.534 0.017
L44.1 Lichen nitidus
0.449 0.534 0.017
T38.9 Other and unspecified hormone antagonists
0.465 0.535 0.000
T38.7 Androgens and anabolic congeners
0.465 0.535 0.000
T38.5 Other oestrogens and progestogens
0.465 0.535 0.000
T38.4 Oral contraceptives
0.465 0.535 0.000
T38.2 Antithyroid drugs
0.465 0.535 0.000
T38.0 Glucocorticoids and synthetic analogues
0.465 0.535 0.000
L24 Irritant contact dermatitis
0.000 0.535 0.465
L26 Exfoliative dermatitis
0.000 0.535 0.465
L22 Diaper [napkin] dermatitis
0.000 0.535 0.465
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.536 0.464
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.462 0.538 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.540 0.460
E29.1 Testicular hypofunction
0.000 0.541 0.459
J95-J99 Other diseases of the respiratory system
0.000 0.543 0.457
J80 Adult respiratory distress syndrome
0.000 0.544 0.456
D61 Other aplastic anaemias
0.000 0.545 0.455
E16.2 Hypoglycaemia, unspecified
0.000 0.545 0.455
E51.2 Wernicke's encephalopathy
0.000 0.548 0.452
L30.5 Pityriasis alba
0.000 0.548 0.452
L30.2 Cutaneous autosensitisation
0.000 0.548 0.452
L30.1 Dyshidrosis [pompholyx]
0.000 0.548 0.452
L30.0 Nummular dermatitis
0.000 0.548 0.452
J60-J70 Lung diseases due to external agents
0.000 0.549 0.451
E51.9 Thiamine deficiency, unspecified
0.000 0.549 0.451
E51.8 Other manifestations of thiamine deficiency
0.000 0.549 0.451
E51.1 Beriberi
0.000 0.549 0.451
J21 Acute bronchiolitis
0.000 0.549 0.451
E50.9 Vitamin A deficiency, unspecified
0.000 0.550 0.450
E50.8 Other manifestations of vitamin A deficiency
0.000 0.550 0.450
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.550 0.450
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.550 0.450
E50.5 Vitamin A deficiency with night blindness
0.000 0.550 0.450
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.550 0.450
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.550 0.450
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.550 0.450
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.550 0.450
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.550 0.450
E56.9 Vitamin deficiency, unspecified
0.000 0.550 0.450
E56.8 Deficiency of other vitamins
0.000 0.550 0.450
E56.1 Deficiency of vitamin K
0.000 0.550 0.450
E56.0 Deficiency of vitamin E
0.000 0.550 0.450
E63.9 Nutritional deficiency, unspecified
0.000 0.550 0.450
E63.8 Other specified nutritional deficiencies
0.000 0.550 0.450
E63.1 Imbalance of constituents of food intake
0.000 0.550 0.450
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.550 0.450
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.550 0.450
E64.8 Sequelae of other nutritional deficiencies
0.000 0.550 0.450
E64.3 Sequelae of rickets
0.000 0.550 0.450
E64.2 Sequelae of vitamin C deficiency
0.000 0.550 0.450
E64.1 Sequelae of vitamin A deficiency
0.000 0.550 0.450
E64.0 Sequelae of protein-energy malnutrition
0.000 0.550 0.450
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.551 0.448
L27.8 Dermatitis due to other substances taken internally
0.000 0.551 0.448
M35.3 Polymyalgia rheumatica
0.000 0.551 0.449
L23 Allergic contact dermatitis
0.000 0.552 0.448
L28 Lichen simplex chronicus and prurigo
0.000 0.553 0.447
J39.8 Other specified diseases of upper respiratory tract
0.000 0.553 0.447
T45.1 Antineoplastic and immunosuppressive drugs
0.446 0.554 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.555 0.445
J20.8 Acute bronchitis due to other specified organisms
0.000 0.560 0.440
K51.4 Pseudopolyposis of colon
0.000 0.561 0.438
E34.9 Endocrine disorder, unspecified
0.000 0.562 0.438
L41.9 Parapsoriasis, unspecified
0.418 0.564 0.018
L41.8 Other parapsoriasis
0.418 0.564 0.018
L41.5 Retiform parapsoriasis
0.418 0.564 0.018
L41.4 Large plaque parapsoriasis
0.418 0.564 0.018
L41.3 Small plaque parapsoriasis
0.418 0.564 0.018
L41.2 Lymphomatoid papulosis
0.418 0.564 0.018
L41.1 Pityriasis lichenoides chronica
0.418 0.564 0.018
L41.0 Pityriasis lichenoides et varioliformis acuta
0.418 0.564 0.018
L30.4 Erythema intertrigo
0.000 0.566 0.434
E16.1 Other hypoglycaemia
0.000 0.568 0.432
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.568 0.432
D84.1 Defects in the complement system
0.000 0.568 0.431
E61.2 Magnesium deficiency
0.000 0.568 0.431
D84.8 Other specified immunodeficiencies
0.000 0.569 0.431
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.569 0.431
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.569 0.431
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.570 0.430
J32.4 Chronic pansinusitis
0.000 0.571 0.429
L29.1 Pruritus scroti
0.000 0.573 0.427
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.575 0.425
G91.9 Hydrocephalus, unspecified
0.000 0.576 0.424
D69.5 Secondary thrombocytopenia
0.000 0.577 0.423
G90 Disorders of autonomic nervous system
0.000 0.577 0.423
T45.9 Primarily systemic and haematological agent, unspecified
0.422 0.578 0.000
T45.8 Other primarily systemic and haematological agents
0.422 0.578 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.422 0.578 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.