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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs442439
log Bayes Factor = 66.7303
Chromosome 6   position 28,573,006  (GRCh37) Explore rs442439 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
E10.9 Without complications
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.996 0.004 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.995 0.005 0.000
E00-E07 Disorders of thyroid gland
0.993 0.007 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.013 0.987
E10.3 With ophthalmic complications
0.964 0.036 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.946 0.054 0.000
E14 Unspecified diabetes mellitus
0.915 0.085 0.000
E13 Other specified diabetes mellitus
0.870 0.130 0.000
E10.4 With neurological complications
0.865 0.135 0.000
E10.2 With renal complications
0.859 0.141 0.000
E14.9 Without complications
0.859 0.141 0.000
E10.1 With ketoacidosis
0.858 0.142 0.000
E10.6 With other specified complications
0.818 0.182 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.214 0.786
E16.0 Drug-induced hypoglycaemia without coma
0.784 0.216 0.000
E13.9 Without complications
0.784 0.216 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.219 0.781
K40 Inguinal hernia
0.000 0.226 0.774
E40-E46 Malnutrition
0.745 0.255 0.000
E16.1 Other hypoglycaemia
0.744 0.256 0.000
E10.0 With coma
0.734 0.266 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.713 0.286 0.000
E05.4 Thyrotoxicosis factitia
0.713 0.286 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.713 0.286 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.713 0.286 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.712 0.288 0.000
E00 Congenital iodine-deficiency syndrome
0.712 0.288 0.000
E10.7 With multiple complications
0.712 0.288 0.000
E05.8 Other thyrotoxicosis
0.705 0.295 0.000
E14.5 With peripheral circulatory complications
0.702 0.298 0.000
E14.4 With neurological complications
0.685 0.315 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.671 0.329 0.000
E14.1 With ketoacidosis
0.670 0.330 0.000
E14.3 With ophthalmic complications
0.665 0.335 0.000
E14.2 Withrenal complications
0.663 0.337 0.000
E14.7 With multiple complications
0.656 0.344 0.000
E14.0 With coma
0.656 0.344 0.000
E14.6 With other specified complications
0.655 0.345 0.000
E10.5 With peripheral circulatory complications
0.646 0.354 0.000
E13.8 With unspecified complications
0.624 0.376 0.000
E13.7 With multiple complications
0.624 0.376 0.000
E13.6 With other specified complications
0.624 0.376 0.000
E13.5 With peripheral circulatory complications
0.624 0.376 0.000
E13.4 With neurological complications
0.624 0.376 0.000
E13.2 With renal complications
0.624 0.376 0.000
E13.1 With ketoacidosis
0.624 0.376 0.000
E13.0 With coma
0.624 0.376 0.000
E13.3 With ophthalmic complications
0.606 0.394 0.000
E07 Other disorders of thyroid
0.594 0.406 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.420 0.580
E46 Unspecified protein-energy malnutrition
0.563 0.437 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.440 0.559
E50-E64 Other nutritional deficiencies
0.557 0.443 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.445 0.555
E06 Thyroiditis
0.553 0.447 0.000
E83 Disorders of mineral metabolism
0.001 0.453 0.546
E44 Protein-energy malnutrition of moderate and mild degree
0.534 0.466 0.000
E45 Retarded development following protein-energy malnutrition
0.534 0.466 0.000
E43 Unspecified severe protein-energy malnutrition
0.534 0.466 0.000
E42 Marasmic kwashiorkor
0.534 0.466 0.000
E41 Nutritional marasmus
0.534 0.466 0.000
E40 Kwashiorkor
0.534 0.466 0.000
E10.8 With unspecified complications
0.523 0.476 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.480 0.520
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.511 0.489 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.511 0.489 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.511 0.489 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.511 0.489 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.511 0.489 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.511 0.489 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.511 0.489 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.511 0.489 0.000
K90 Intestinal malabsorption
0.503 0.496 0.000
E14.8 With unspecified complications
0.485 0.515 0.000
E07.8 Other specified disorders of thyroid
0.463 0.537 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.453 0.546 0.000
E61 Deficiency of other nutrient elements
0.447 0.553 0.000
E07.1 Dyshormogenetic goitre
0.426 0.574 0.000
E07.0 Hypersecretion of calcitonin
0.426 0.574 0.000
E06.5 Other chronic thyroiditis
0.419 0.581 0.000
E06.9 Thyroiditis, unspecified
0.414 0.586 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.413 0.586 0.000
E56 Other vitamin deficiencies
0.405 0.595 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.400 0.600 0.000
E63 Other nutritional deficiencies
0.400 0.600 0.000
E50 Vitamin A deficiency
0.400 0.600 0.000
E60 Dietary zinc deficiency
0.400 0.600 0.000
E59 Dietary selenium deficiency
0.400 0.600 0.000
E54 Ascorbic acid deficiency
0.400 0.600 0.000
E52 Niacin deficiency [pellagra]
0.400 0.600 0.000
E06.4 Drug-induced thyroiditis
0.397 0.603 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.397 0.603 0.000
E06.1 Subacute thyroiditis
0.397 0.603 0.000
E06.0 Acute thyroiditis
0.397 0.603 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.608 0.392
E83.8 Other disorders of mineral metabolism
0.001 0.608 0.392
E83.2 Disorders of zinc metabolism
0.001 0.608 0.392
E83.0 Disorders of copper metabolism
0.001 0.608 0.392
K90.8 Other intestinal malabsorption
0.390 0.610 0.000
E51 Thiamine deficiency
0.390 0.610 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.615 0.385
E61.1 Iron deficiency
0.385 0.615 0.000
E58 Dietary calcium deficiency
0.383 0.617 0.000
E44.1 Mild protein-energy malnutrition
0.383 0.617 0.000
E44.0 Moderate protein-energy malnutrition
0.383 0.617 0.000
K90.3 Pancreatic steatorrhoea
0.361 0.639 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.361 0.639 0.000
K90.1 Tropical sprue
0.361 0.639 0.000
E61.9 Deficiency of nutrient element, unspecified
0.320 0.680 0.000
E61.8 Deficiency of other specified nutrient elements
0.320 0.680 0.000
E61.7 Deficiency of multiple nutrient elements
0.320 0.680 0.000
E61.6 Vanadium deficiency
0.320 0.680 0.000
E61.5 Molybdenum deficiency
0.320 0.680 0.000
E61.4 Chromium deficiency
0.320 0.680 0.000
E61.3 Manganese deficiency
0.320 0.680 0.000
E61.0 Copper deficiency
0.320 0.680 0.000
E53 Deficiency of other B group vitamins
0.307 0.692 0.000
E55 Vitamin D deficiency
0.307 0.693 0.000
E03 Other hypothyroidism
0.303 0.697 0.000
E20-E35 Disorders of other endocrine glands
0.300 0.700 0.000
E65-E68 Obesity and other hyperalimentation
0.299 0.701 0.000
E56.1 Deficiency of vitamin K
0.295 0.705 0.000
E56.9 Vitamin deficiency, unspecified
0.290 0.710 0.000
E56.8 Deficiency of other vitamins
0.290 0.710 0.000
E56.0 Deficiency of vitamin E
0.290 0.710 0.000
K90.9 Intestinal malabsorption, unspecified
0.289 0.711 0.000
E50.9 Vitamin A deficiency, unspecified
0.287 0.713 0.000
E50.8 Other manifestations of vitamin A deficiency
0.287 0.713 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.287 0.713 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.287 0.713 0.000
E50.5 Vitamin A deficiency with night blindness
0.287 0.713 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.287 0.713 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.287 0.713 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.287 0.713 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.287 0.713 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.287 0.713 0.000
E63.9 Nutritional deficiency, unspecified
0.287 0.713 0.000
E63.8 Other specified nutritional deficiencies
0.287 0.713 0.000
E63.1 Imbalance of constituents of food intake
0.287 0.713 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.287 0.713 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.287 0.713 0.000
E64.8 Sequelae of other nutritional deficiencies
0.287 0.713 0.000
E64.3 Sequelae of rickets
0.287 0.713 0.000
E64.2 Sequelae of vitamin C deficiency
0.287 0.713 0.000
E64.1 Sequelae of vitamin A deficiency
0.287 0.713 0.000
E64.0 Sequelae of protein-energy malnutrition
0.287 0.713 0.000
E61.2 Magnesium deficiency
0.284 0.715 0.000
E51.9 Thiamine deficiency, unspecified
0.280 0.720 0.000
E51.8 Other manifestations of thiamine deficiency
0.280 0.720 0.000
E51.1 Beriberi
0.280 0.720 0.000
E51.2 Wernicke's encephalopathy
0.270 0.730 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.743 0.257
E20 Hypoparathyroidism
0.233 0.767 0.000
E24 Cushing's syndrome
0.231 0.769 0.000
E07.9 Disorder of thyroid, unspecified
0.229 0.771 0.000
E31 Polyglandular dysfunction
0.226 0.774 0.000
E53.1 Pyridoxine deficiency
0.221 0.779 0.000
E53.0 Riboflavin deficiency
0.221 0.779 0.000
E55.0 Rickets, active
0.220 0.780 0.000
E03.5 Myxoedema coma
0.217 0.783 0.000
E03.4 Atrophy of thyroid (acquired)
0.217 0.783 0.000
E03.3 Postinfectious hypothyroidism
0.217 0.783 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.215 0.785 0.000
E32 Diseases of thymus
0.215 0.785 0.000
E30 Disorders of puberty, not elsewhere classified
0.215 0.785 0.000
E25 Adrenogenital disorders
0.215 0.785 0.000
E67 Other hyperalimentation
0.215 0.785 0.000
E68 Sequelae of hyperalimentation
0.215 0.785 0.000
E53.9 Vitamin B deficiency, unspecified
0.214 0.786 0.000
E03.1 Congenital hypothyroidism without goitre
0.213 0.787 0.000
E27 Other disorders of adrenal gland
0.211 0.789 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.207 0.793 0.000
E29 Testicular dysfunction
0.204 0.796 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.202 0.798 0.000
E03.8 Other specified hypothyroidism
0.199 0.801 0.000
E23 Hypofunction and other disorders of pituitary gland
0.194 0.806 0.000
E34 Other endocrine disorders
0.189 0.811 0.000
E24.0 Pituitary-dependent Cushing's disease
0.187 0.812 0.000
E24.2 Drug-induced Cushing's syndrome
0.185 0.815 0.000
E27.1 Primary adrenocortical insufficiency
0.184 0.816 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.180 0.820 0.000
E20.8 Other hypoparathyroidism
0.178 0.822 0.000
E20.9 Hypoparathyroidism, unspecified
0.177 0.823 0.000
E26 Hyperaldosteronism
0.177 0.823 0.000
E28 Ovarian dysfunction
0.176 0.824 0.000
E31.0 Autoimmune polyglandular failure
0.172 0.828 0.000
E20.1 Pseudohypoparathyroidism
0.167 0.832 0.000
E20.0 Idiopathic hypoparathyroidism
0.167 0.832 0.000
E24.8 Other Cushing's syndrome
0.166 0.834 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.166 0.834 0.000
E24.3 Ectopic ACTH syndrome
0.166 0.834 0.000
E24.1 Nelson's syndrome
0.166 0.834 0.000
E31.9 Polyglandular dysfunction, unspecified
0.162 0.838 0.000
E31.8 Other polyglandular dysfunction
0.162 0.838 0.000
E31.1 Polyglandular hyperfunction
0.162 0.838 0.000
E27.2 Addisonian crisis
0.157 0.843 0.000
E25.9 Adrenogenital disorder, unspecified
0.154 0.845 0.000
E25.8 Other adrenogenital disorders
0.154 0.845 0.000
E30.9 Disorder of puberty, unspecified
0.154 0.845 0.000
E30.8 Other disorders of puberty
0.154 0.845 0.000
E30.1 Precocious puberty
0.154 0.845 0.000
E30.0 Delayed puberty
0.154 0.845 0.000
E32.9 Disease of thymus, unspecified
0.154 0.845 0.000
E32.8 Other diseases of thymus
0.154 0.845 0.000
E32.1 Abscess of thymus
0.154 0.845 0.000
E32.0 Persistent hyperplasia of thymus
0.154 0.845 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.154 0.845 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.154 0.845 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.154 0.845 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.154 0.845 0.000
E67.8 Other specified hyperalimentation
0.154 0.846 0.000
E67.3 Hypervitaminosis D
0.154 0.846 0.000
E67.2 Megavitamin-B6 syndrome
0.154 0.846 0.000
E67.1 Hypercarotenaemia
0.154 0.846 0.000
E67.0 Hypervitaminosis A
0.154 0.846 0.000
E23.6 Other disorders of pituitary gland
0.153 0.847 0.000
E27.5 Adrenomedullary hyperfunction
0.151 0.848 0.000
E27.0 Other adrenocortical overactivity
0.151 0.848 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.151 0.849 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.148 0.852 0.000
E22 Hyperfunction of pituitary gland
0.147 0.853 0.000
E29.9 Testicular dysfunction, unspecified
0.146 0.854 0.000
E29.8 Other testicular dysfunction
0.146 0.854 0.000
E29.0 Testicular hyperfunction
0.146 0.854 0.000
E21.3 Hyperparathyroidism, unspecified
0.145 0.855 0.000
E65 Localised adiposity
0.143 0.857 0.000
E34.9 Endocrine disorder, unspecified
0.142 0.857 0.000
E21.4 Other specified disorders of parathyroid gland
0.142 0.858 0.000
E27.9 Disorder of adrenal gland, unspecified
0.141 0.858 0.000
E53.8 Deficiency of other specified B group vitamins
0.141 0.859 0.000
E23.7 Disorder of pituitary gland, unspecified
0.140 0.860 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.139 0.861 0.000
E23.1 Drug-induced hypopituitarism
0.139 0.861 0.000
E06.3 Autoimmune thyroiditis
0.138 0.861 0.001
E23.2 Diabetes insipidus
0.137 0.863 0.000
E34.5 Androgen resistance syndrome
0.136 0.864 0.000
E34.4 Constitutional tall stature
0.136 0.864 0.000
E34.3 Short stature, not elsewhere classified
0.136 0.864 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.136 0.864 0.000
E34.1 Other hypersecretion of intestinal hormones
0.136 0.864 0.000
E29.1 Testicular hypofunction
0.135 0.865 0.000
I83 Varicose veins of lower extremities
0.000 0.870 0.130
E24.9 Cushing's syndrome, unspecified
0.128 0.872 0.000
E55.9 Vitamin D deficiency, unspecified
0.128 0.872 0.000
E26.9 Hyperaldosteronism, unspecified
0.127 0.873 0.000
E26.8 Other hyperaldosteronism
0.127 0.873 0.000
E26.1 Secondary hyperaldosteronism
0.127 0.873 0.000
E28.9 Ovarian dysfunction, unspecified
0.126 0.874 0.000
E28.8 Other ovarian dysfunction
0.126 0.874 0.000
E28.1 Androgen excess
0.126 0.874 0.000
E28.0 Oestrogen excess
0.126 0.874 0.000
E34.8 Other specified endocrine disorders
0.125 0.875 0.000
E21.2 Other hyperparathyroidism
0.124 0.875 0.000
E28.3 Primary ovarian failure
0.121 0.879 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.121 0.879 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.886 0.114
E34.0 Carcinoid syndrome
0.113 0.886 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.108 0.892 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.105 0.894 0.000
E22.8 Other hyperfunction of pituitary gland
0.105 0.894 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.100 0.899 0.000
E28.2 Polycystic ovarian syndrome
0.095 0.904 0.000
E21.0 Primary hyperparathyroidism
0.095 0.905 0.000
E23.0 Hypopituitarism
0.094 0.906 0.000
E22.1 Hyperprolactinaemia
0.093 0.907 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.907 0.093
K51 Ulcerative colitis
0.000 0.908 0.092
E26.0 Primary hyperaldosteronism
0.088 0.911 0.000
E27.8 Other specified disorders of adrenal gland
0.088 0.912 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.913 0.087
E04 Other non-toxic goitre
0.085 0.915 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.915 0.085
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.932 0.068
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.932 0.068
R30-R39 Symptoms and signs involving the urinary system
0.000 0.935 0.065
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.936 0.064
K51.4 Pseudopolyposis of colon
0.000 0.936 0.064
R39 Other symptoms and signs involving the urinary system
0.000 0.937 0.063
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.937 0.063
E04.8 Other specified non-toxic goitre
0.061 0.938 0.000
K51.5 Mucosal proctocolitis
0.000 0.941 0.059
E22.0 Acromegaly and pituitary gigantism
0.056 0.943 0.000
C25.9 Pancreas, unspecified
0.055 0.945 0.000
C25 Malignant neoplasm of pancreas
0.052 0.948 0.000
R39.1 Other difficulties with micturition
0.000 0.954 0.046
C25.0 Head of pancreas
0.046 0.954 0.000
R39.2 Extrarenal uraemia
0.000 0.954 0.046
R36 Urethral discharge
0.000 0.955 0.044
C25.2 Tail of pancreas
0.044 0.956 0.000
R30 Pain associated with micturition
0.000 0.959 0.041
E04.0 Non-toxic diffuse goitre
0.040 0.959 0.000
C25.8 Overlapping lesion of pancreas
0.039 0.960 0.000
C25.3 Pancreatic duct
0.039 0.961 0.000
C25.4 Endocrine pancreas
0.039 0.961 0.000
E04.9 Non-toxic goitre, unspecified
0.039 0.961 0.000
E11 Non-insulin-dependent diabetes mellitus
0.038 0.962 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.036 0.964 0.000
R30.1 Vesical tenesmus
0.000 0.964 0.036
C25.7 Other parts of pancreas
0.036 0.964 0.000
C15-C26 Malignant neoplasms of digestive organs
0.036 0.964 0.000
R39.0 Extravasation of urine
0.000 0.964 0.035
K51.8 Other ulcerative colitis
0.000 0.965 0.035
K90-K93 Other diseases of the digestive system
0.031 0.966 0.004
C25.1 Body of pancreas
0.033 0.966 0.000
E11.1 With ketoacidosis
0.033 0.967 0.000
C18.9 Colon, unspecified
0.032 0.968 0.000
R34 Anuria and oliguria
0.000 0.970 0.030
E04.1 Non-toxic single thyroid nodule
0.030 0.970 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.971 0.029
E11.0 With coma
0.029 0.971 0.000
E83.5 Disorders of calcium metabolism
0.001 0.971 0.028
C20 Malignant neoplasm of rectum
0.029 0.971 0.000
C18 Malignant neoplasm of colon
0.028 0.972 0.000
E11.7 With multiple complications
0.027 0.973 0.000
E66 Obesity
0.027 0.973 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.027 0.973 0.000
C17 Malignant neoplasm of small intestine
0.026 0.973 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.974 0.026
C23 Malignant neoplasm of gallbladder
0.026 0.974 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.026 0.974 0.000
C15 Malignant neoplasm of oesophagus
0.026 0.974 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.022 0.975 0.003
E11.6 With other specified complications
0.025 0.975 0.000
C18.6 Descending colon
0.024 0.976 0.000
E11.8 With unspecified complications
0.024 0.976 0.000
C24.0 Extrahepatic bile duct
0.023 0.977 0.000
C17.0 Duodenum
0.023 0.977 0.000
R30.9 Painful micturition, unspecified
0.000 0.977 0.023
K50-K52 Noninfective enteritis and colitis
0.000 0.977 0.023
C15.4 Middle third of oesophagus
0.022 0.978 0.000
R35 Polyuria
0.000 0.978 0.022
M67.8 Other specified disorders of synovium and tendon
0.022 0.978 0.000
E11.5 With peripheral circulatory complications
0.022 0.978 0.000
C15.0 Cervical part of oesophagus
0.022 0.978 0.000
C18.4 Transverse colon
0.022 0.978 0.000
C18.8 Overlapping lesion of colon
0.021 0.979 0.000
C24.9 Biliary tract, unspecified
0.021 0.979 0.000
C22.1 Intrahepatic bile duct carcinoma
0.021 0.979 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.021 0.979 0.000
K40-K46 Hernia
0.000 0.980 0.020
C22.9 Liver, unspecified
0.020 0.980 0.000
C18.7 Sigmoid colon
0.020 0.980 0.000
S02.20 Fracture of nasal bones (closed)
0.020 0.980 0.000
E66.1 Drug-induced obesity
0.020 0.980 0.000
C24.8 Overlapping lesion of biliary tract
0.020 0.980 0.000
C15.1 Thoracic part of oesophagus
0.019 0.980 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.019 0.981 0.000
E70-E90 Metabolic disorders
0.012 0.981 0.007
C17.8 Overlapping lesion of small intestine
0.019 0.981 0.000
C17.3 Meckel's diverticulum
0.019 0.981 0.000
C17.1 Jejunum
0.019 0.981 0.000
C22.7 Other specified carcinomas of liver
0.019 0.981 0.000
C22.4 Other sarcomas of liver
0.019 0.981 0.000
C22.3 Angiosarcoma of liver
0.019 0.981 0.000
C22.2 Hepatoblastoma
0.019 0.981 0.000
C15.8 Overlapping lesion of oesophagus
0.018 0.981 0.000
C15.2 Abdominal part of oesophagus
0.018 0.981 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.018 0.981 0.000
S02.4 Fracture of malar and maxillary bones
0.019 0.981 0.000
S02.2 Fracture of nasal bones
0.018 0.982 0.000
M67 Other disorders of synovium and tendon
0.018 0.982 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.016 0.982 0.002
K93.1 Megacolon in Chagas' disease
0.016 0.982 0.002
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.016 0.982 0.002
R30.0 Dysuria
0.000 0.982 0.018
K50 Crohn's disease [regional enteritis]
0.000 0.982 0.018
C17.9 Small intestine, unspecified
0.018 0.982 0.000
S02 Fracture of skull and facial bones
0.017 0.983 0.000
C15.3 Upper third of oesophagus
0.017 0.983 0.000
K50.1 Crohn's disease of large intestine
0.000 0.983 0.017
C21 Malignant neoplasm of anus and anal canal
0.017 0.983 0.000
I20.8 Other forms of angina pectoris
0.000 0.983 0.017
M67.2 Synovial hypertrophy, not elsewhere classified
0.016 0.984 0.000
M67.0 Short Achilles tendon (acquired)
0.016 0.984 0.000
S02.8 Fractures of other skull and facial bones
0.016 0.984 0.000
K41 Femoral hernia
0.000 0.984 0.016
C16 Malignant neoplasm of stomach
0.016 0.984 0.000
C17.2 Ileum
0.016 0.984 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.016 0.984 0.000
C18.5 Splenic flexure
0.015 0.985 0.000
N50.8 Other specified disorders of male genital organs
0.015 0.985 0.000
S02.5 Fracture of tooth
0.015 0.985 0.000
C18.3 Hepatic flexure
0.015 0.985 0.000
K50.8 Other Crohn's disease
0.000 0.985 0.015
C22.0 Liver cell carcinoma
0.015 0.985 0.000
E84 Cystic fibrosis
0.010 0.986 0.004
C26.8 Overlapping lesion of digestive system
0.014 0.986 0.000
C26.1 Spleen
0.014 0.986 0.000
E77 Disorders of glycoprotein metabolism
0.009 0.986 0.005
E76 Disorders of glycosaminoglycan metabolism
0.009 0.986 0.005
E72 Other disorders of amino-acid metabolism
0.009 0.986 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.009 0.986 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.009 0.986 0.005
E70 Disorders of aromatic amino-acid metabolism
0.009 0.986 0.005
C15.9 Oesophagus, unspecified
0.014 0.986 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.009 0.986 0.005
S02.21 Fracture of nasal bones (open)
0.014 0.986 0.000
C18.1 Appendix
0.014 0.986 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.013 0.986 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.986 0.013
E79 Disorders of purine and pyrimidine metabolism
0.007 0.987 0.006
S02.50 Fracture of tooth (closed)
0.013 0.987 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.013 0.987 0.000
M67.3 Transient synovitis
0.013 0.987 0.000
E11.2 With renal complications
0.013 0.987 0.000
S02.7 Multiple fractures involving skull and facial bones
0.013 0.987 0.000
I73.9 Peripheral vascular disease, unspecified
0.013 0.987 0.000
E74 Other disorders of carbohydrate metabolism
0.008 0.987 0.005
C16.5 Lesser curvature of stomach, unspecified
0.013 0.987 0.000
C24.1 Ampulla of Vater
0.013 0.987 0.000
E73 Lactose intolerance
0.008 0.987 0.005
E66.0 Obesity due to excess calories
0.013 0.987 0.000
M67.4 Ganglion
0.013 0.987 0.000
S02.0 Fracture of vault of skull
0.013 0.987 0.000
C16.6 Greater curvature of stomach, unspecified
0.013 0.987 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.012 0.987 0.000
R32 Unspecified urinary incontinence
0.000 0.988 0.012
C21.2 Cloacogenic zone
0.012 0.988 0.000
E85 Amyloidosis
0.007 0.988 0.005
S02.3 Fracture of orbital floor
0.012 0.988 0.000
S02.81 Fractures of other skull and facial bones (open)
0.012 0.988 0.000
C16.8 Overlapping lesion of stomach
0.012 0.988 0.000
C26.0 Intestinal tract, part unspecified
0.012 0.988 0.000
K50.0 Crohn's disease of small intestine
0.000 0.988 0.012
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.988 0.011
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.988 0.011
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.988 0.011
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.988 0.012
K92.9 Disease of digestive system, unspecified
0.000 0.989 0.011
E88 Other metabolic disorders
0.008 0.989 0.003
C15.5 Lower third of oesophagus
0.011 0.989 0.000
C26.9 Ill-defined sites within the digestive system
0.011 0.989 0.000
K45 Other abdominal hernia
0.000 0.989 0.011
E87.0 Hyperosmolality and hypernatraemia
0.011 0.989 0.000
S02.51 Fracture of tooth (open)
0.011 0.989 0.000
C16.1 Fundus of stomach
0.011 0.989 0.000
E84.9 Cystic fibrosis, unspecified
0.008 0.989 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.007 0.989 0.003
C16.2 Body of stomach
0.010 0.989 0.000
E84.8 Cystic fibrosis with other manifestations
0.007 0.990 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.007 0.990 0.003
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.990 0.010
M65-M68 Disorders of synovium and tendon
0.010 0.990 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.006 0.990 0.005
E71.3 Disorders of fatty-acid metabolism
0.007 0.990 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.007 0.990 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.007 0.990 0.004
E71.0 Maple-syrup-urine disease
0.007 0.990 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.007 0.990 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.007 0.990 0.004
E72.5 Disorders of glycine metabolism
0.007 0.990 0.004
E72.4 Disorders of ornithine metabolism
0.007 0.990 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.007 0.990 0.004
E72.2 Disorders of urea cycle metabolism
0.007 0.990 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.007 0.990 0.004
E72.0 Disorders of amino-acid transport
0.007 0.990 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.007 0.990 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.007 0.990 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.007 0.990 0.004
E76.2 Other mucopolysaccharidoses
0.007 0.990 0.004
E76.1 Mucopolysaccharidosis, type II
0.007 0.990 0.004
E76.0 Mucopolysaccharidosis, type I
0.007 0.990 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.007 0.990 0.004
E77.8 Other disorders of glycoprotein metabolism
0.007 0.990 0.004
E77.1 Defects in glycoprotein degradation
0.007 0.990 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.007 0.990 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.007 0.990 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.007 0.990 0.004
E70.2 Disorders of tyrosine metabolism
0.007 0.990 0.004
E70.1 Other hyperphenylalaninaemias
0.007 0.990 0.004
E70.0 Classical phenylketonuria
0.007 0.990 0.004
H40.2 Primary angle-closure glaucoma
0.000 0.990 0.010
S02.70 Multiple fractures involving skull and facial bones (closed)
0.010 0.990 0.000
E75.6 Lipid storage disorder, unspecified
0.007 0.990 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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