TreeWAS – Variant ID: rs4502542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
# Top node	0.604	0.396
Chapter XXI Factors influencing health status and contact with health services	0.632	0.368
Chapter XIV Diseases of the genitourinary system	0.643	0.357
Chapter XV Pregnancy, childbirth and the puerperium	0.644	0.356
Chapter V Mental and behavioural disorders	0.648	0.352
Chapter IX Diseases of the circulatory system	0.655	0.344
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.666	0.334
Chapter IV Endocrine, nutritional and metabolic diseases	0.670	0.330
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.672	0.328
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.672	0.328
Chapter X Diseases of the respiratory system	0.683	0.317
Chapter VII Diseases of the eye and adnexa	0.684	0.316
Chapter VIII Diseases of the ear and mastoid process	0.685	0.315
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.688	0.312
Z70-Z76 Persons encountering health services in other circumstances	0.697	0.303
Chapter XI Diseases of the digestive system	0.698	0.301
N40-N51 Diseases of male genital organs	0.700	0.300
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.701	0.299
Z86 Personal history of certain other diseases	0.701	0.299
Chapter XII Diseases of the skin and subcutaneous tissue	0.701	0.298
F30-F39 Mood [affective] disorders	0.703	0.297
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.707	0.293
N80-N98 Noninflammatory disorders of female genital tract	0.709	0.291
O60-O75 Complications of labour and delivery	0.710	0.290
N17-N19 Renal failure	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
Chapter I Certain infectious and parasitic diseases	0.717	0.283
I60-I69 Cerebrovascular diseases	0.717	0.282
Chapter XXII Codes for special purposes	0.719	0.281
Chapter VI Diseases of the nervous system	0.719	0.281
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.721	0.279
Z00-Z13 Persons encountering health services for examination and investigation	0.721	0.279
E10-E14 Diabetes mellitus	0.721	0.279
Z92 Personal history of medical treatment	0.722	0.278
F40-F48 Neurotic, stress-related and somatoform disorders	0.723	0.277
O20-O29 Other maternal disorders predominantly related to pregnancy	0.724	0.276
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.725	0.275
N70-N77 Inflammatory diseases of female pelvic organs	0.726	0.274
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.730	0.270
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.730	0.270
N25-N29 Other disorders of kidney and ureter	0.731	0.269
O80-O84 Delivery	0.731	0.269
H30-H36 Disorders of choroid and retina	0.731	0.269
M20-M25 Other joint disorders	0.732	0.268
D50-D53 Nutritional anaemias	0.732	0.268
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.732	0.267
Z88.0 Personal history of allergy to penicillin	0.734	0.266
O00-O08 Pregnancy with abortive outcome	0.736	0.264
Z86.4 Personal history of psychoactive substance abuse	0.736	0.263
I05-I09 Chronic rheumatic heart diseases	0.739	0.261
N00-N08 Glomerular diseases	0.740	0.260
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.740	0.260
F00-F09 Organic, including symptomatic, mental disorders	0.740	0.259
E70-E90 Metabolic disorders	0.741	0.259
O85-O92 Complications predominantly related to the puerperium	0.741	0.259
I10-I15 Hypertensive diseases	0.742	0.258
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.742	0.258
I95-I99 Other and unspecified disorders of the circulatory system	0.743	0.257
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.743	0.257
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.743	0.257
D70-D77 Other diseases of blood and blood-forming organs	0.744	0.256
I70-I79 Diseases of arteries, arterioles and capillaries	0.744	0.256
N40 Hyperplasia of prostate	0.745	0.255
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.745	0.254
N95 Menopausal and other perimenopausal disorders	0.745	0.254
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.747	0.253
F70-F79 Mental retardation	0.747	0.253
N99-N99 Other disorders of the genitourinary system	0.748	0.252
F99-F99 Unspecified mental disorder	0.748	0.252
F80-F89 Disorders of psychological development	0.748	0.252
M05-M14 Inflammatory polyarthropathies	0.748	0.252
M70-M79 Other soft tissue disorders	0.748	0.252
F60-F69 Disorders of adult personality and behaviour	0.749	0.251
Chapter XX External causes of morbidity and mortality	0.749	0.251
H90-H95 Other disorders of ear	0.749	0.250
N30-N39 Other diseases of urinary system	0.750	0.250
I20-I25 Ischaemic heart diseases	0.750	0.249
O94-O99 Other obstetric conditions, not elsewhere classified	0.751	0.249
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.751	0.249
Z36 Antenatal screening	0.751	0.249
Z72 Problems related to lifestyle	0.752	0.248
Chapter II Neoplasms	0.752	0.248
M80-M85 Disorders of bone density and structure	0.753	0.247
I00-I02 Acute rheumatic fever	0.753	0.247
N60-N64 Disorders of breast	0.753	0.247
N10-N16 Renal tubulo-interstitial diseases	0.753	0.246
J20-J22 Other acute lower respiratory infections	0.753	0.246
Z81 Family history of mental and behavioural disorders	0.754	0.246
Z95 Presence of cardiac and vascular implants and grafts	0.754	0.246
J40-J47 Chronic lower respiratory diseases	0.755	0.245
Z89 Acquired absence of limb	0.756	0.244
K20-K31 Diseases of oesophagus, stomach and duodenum	0.757	0.243
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.758	0.242
O36 Maternal care for other known or suspected foetal problems	0.758	0.242
M65-M68 Disorders of synovium and tendon	0.759	0.241
Z86.7 Personal history of diseases of the circulatory system	0.759	0.241
D60-D64 Aplastic and other anaemias	0.760	0.240
Z91 Personal history of risk-factors, not elsewhere classified	0.761	0.239
Z85 Personal history of malignant neoplasm	0.761	0.239
Z86.0 Personal history of other neoplasms	0.761	0.239
H65-H75 Diseases of middle ear and mastoid	0.761	0.239
Z84 Family history of other conditions	0.761	0.239
Z34 Supervision of normal pregnancy	0.761	0.239
E50-E64 Other nutritional deficiencies	0.762	0.238
M86-M90 Other osteopathies	0.762	0.238
N18 Chronic renal failure	0.762	0.238
M60-M63 Disorders of muscles	0.762	0.237
J09-J18 Influenza and pneumonia	0.763	0.237
Z30 Contraceptive management	0.763	0.237
Z37 Outcome of delivery	0.763	0.237
J95-J99 Other diseases of the respiratory system	0.763	0.237
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.764	0.236
E40-E46 Malnutrition	0.764	0.236
H53-H54 Visual disturbances and blindness	0.764	0.235
Z97 Presence of other devices	0.765	0.235
Z94 Transplanted organ and tissue status	0.765	0.235
E65-E68 Obesity and other hyperalimentation	0.765	0.235
N20-N23 Urolithiasis	0.765	0.235
D55-D59 Haemolytic anaemias	0.765	0.235
M00-M03 Infectious arthropathies	0.765	0.235
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.766	0.234
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.766	0.234
M91-M94 Chondropathies	0.766	0.234
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.767	0.233
E11 Non-insulin-dependent diabetes mellitus	0.767	0.233
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.767	0.233
M45-M49 Spondylopathies	0.767	0.232
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.767	0.232
D80-D89 Certain disorders involving the immune mechanism	0.768	0.232
O68 Labour and delivery complicated by foetal stress [distress]	0.769	0.231
K70-K77 Diseases of liver	0.769	0.231
Z83 Family history of other specific disorders	0.769	0.231
M40-M43 Deforming dorsopathies	0.769	0.231
H46-H48 Disorders of optic nerve and visual pathways	0.769	0.230
E00-E07 Disorders of thyroid gland	0.771	0.229
I30-I52 Other forms of heart disease	0.771	0.229
J80-J84 Other respiratory diseases principally affecting the interstitium	0.771	0.229
H55-H59 Other disorders of eye and adnexa	0.771	0.229
Z39 Postpartum care and examination	0.771	0.228
F32 Depressive episode	0.772	0.228
E20-E35 Disorders of other endocrine glands	0.772	0.228
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.772	0.228
F31 Bipolar affective disorder	0.773	0.227
H60-H62 Diseases of external ear	0.773	0.227
Z98 Other postsurgical states	0.774	0.226
Z93 Artificial opening status	0.774	0.226
N95.0 Postmenopausal bleeding	0.774	0.226
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.775	0.225
J60-J70 Lung diseases due to external agents	0.775	0.225
Z88.1 Personal history of allergy to other antibiotic agents	0.775	0.224
H10-H13 Disorders of conjunctiva	0.776	0.224
G40-G47 Episodic and paroxysmal disorders	0.776	0.224
J00-J06 Acute upper respiratory infections	0.776	0.224
Z38 Liveborn infants according to place of birth	0.776	0.224
Z76 Persons encountering health services in other circumstances	0.777	0.223
Z32 Pregnancy examination and test	0.777	0.223
F41 Other anxiety disorders	0.777	0.223
H40-H42 Glaucoma	0.777	0.223
K90-K93 Other diseases of the digestive system	0.777	0.223
F33 Recurrent depressive disorder	0.777	0.223
Z31 Procreative management	0.777	0.223
H35 Other retinal disorders	0.777	0.222
L00-L08 Infections of the skin and subcutaneous tissue	0.777	0.222
Z74 Problems related to care-provider dependency	0.778	0.222
K35-K38 Diseases of appendix	0.778	0.222
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.778	0.222
Z73 Problems related to life-management difficulty	0.778	0.222
N41 Inflammatory diseases of prostate	0.778	0.222
H43-H45 Disorders of vitreous body and globe	0.778	0.222
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.778	0.221
Z88.3 Personal history of allergy to other anti-infective agents	0.778	0.222
Z33 Pregnant state, incidental	0.778	0.221
F39 Unspecified mood [affective] disorder	0.779	0.221
Z96 Presence of other functional implants	0.779	0.221
L80-L99 Other disorders of the skin and subcutaneous tissue	0.779	0.221
H80-H83 Diseases of inner ear	0.779	0.220
N88 Other noninflammatory disorders of cervix uteri	0.779	0.220
M15-M19 Arthrosis	0.780	0.220
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.780	0.220
L60-L75 Disorders of skin appendages	0.780	0.220
M50-M54 Other dorsopathies	0.780	0.220
Z92.2 Personal history of long-term (current) use of other medicaments	0.780	0.220
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.780	0.219
Z35 Supervision of high-risk pregnancy	0.780	0.219
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.781	0.219
F38 Other mood [affective] disorders	0.781	0.219
N84 Polyp of female genital tract	0.781	0.219
Z86.5 Personal history of other mental and behavioural disorders	0.781	0.219
M20 Acquired deformities of fingers and toes	0.781	0.219
N45 Orchitis and epididymitis	0.781	0.219
F30 Manic episode	0.781	0.219
N93 Other abnormal uterine and vaginal bleeding	0.781	0.219
N50 Other disorders of male genital organs	0.781	0.218
O62 Abnormalities of forces of labour	0.782	0.218
O32 Maternal care for known or suspected malpresentation of foetus	0.782	0.218
O70 Perineal laceration during delivery	0.782	0.218
I67 Other cerebrovascular diseases	0.782	0.218
O42 Premature rupture of membranes	0.782	0.218
A00-A09 Intestinal infectious diseases	0.782	0.217
Z70 Counselling related to sexual attitude, behaviour and orientation	0.782	0.217
N43 Hydrocele and spermatocele	0.783	0.217
H25-H28 Disorders of lens	0.783	0.216
F10 Mental and behavioural disorders due to use of alcohol	0.783	0.216
Z90 Acquired absence of organs, not elsewhere classified	0.784	0.216
L50-L54 Urticaria and erythema	0.784	0.216
D50 Iron deficiency anaemia	0.784	0.216
J30-J39 Other diseases of upper respiratory tract	0.784	0.216
K40-K46 Hernia	0.784	0.216
K50-K52 Noninfective enteritis and colitis	0.784	0.215
L20-L30 Dermatitis and eczema	0.784	0.215
O44 Placenta praevia	0.785	0.215
N51 Disorders of male genital organs in diseases classified elsewhere	0.785	0.215
N44 Torsion of testis	0.785	0.215
N87 Dysplasia of cervix uteri	0.785	0.215
N47 Redundant prepuce, phimosis and paraphimosis	0.785	0.215
N46 Male infertility	0.785	0.215
Z75 Problems related to medical facilities and other health care	0.785	0.215
O26 Maternal care for other conditions predominantly related to pregnancy	0.785	0.215
Z11 Special screening examination for infectious and parasitic diseases	0.785	0.215
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.785	0.215
J90-J94 Other diseases of pleura	0.785	0.214
I26 Pulmonary embolism	0.785	0.214
N48 Other disorders of penis	0.786	0.214
I64 Stroke, not specified as haemorrhage or infarction	0.786	0.214
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.786	0.214
Z88.7 Personal history of allergy to serum and vaccine	0.786	0.214
L10-L14 Bullous disorders	0.786	0.214
I62 Other nontraumatic intracranial haemorrhage	0.786	0.213
O73 Retained placenta and membranes, without haemorrhage	0.786	0.213
Z88.4 Personal history of allergy to anaesthetic agent	0.786	0.213
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.787	0.213
O63 Long labour	0.787	0.213
F34 Persistent mood [affective] disorders	0.787	0.213
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.787	0.213
O48 Prolonged pregnancy	0.787	0.212
Z88.6 Personal history of allergy to analgesic agent	0.788	0.212
R30-R39 Symptoms and signs involving the urinary system	0.788	0.212
Z92.1 Personal history of long-term (current) use of anticoagulants	0.789	0.211
Z80 Family history of malignant neoplasm	0.789	0.211
L40-L45 Papulosquamous disorders	0.789	0.211
K65-K67 Diseases of peritoneum	0.789	0.211
E10 Insulin-dependent diabetes mellitus	0.789	0.211
S20-S29 Injuries to the thorax	0.789	0.211
Z88.2 Personal history of allergy to sulphonamides	0.789	0.211
N80 Endometriosis	0.789	0.210
N42 Other disorders of prostate	0.789	0.210
Z92.3 Personal history of irradiation	0.790	0.210
O31 Complications specific to multiple gestation	0.790	0.210
O45 Premature separation of placenta [abruptio placentae]	0.790	0.210
Z92.4 Personal history of major surgery, not elsewhere classified	0.790	0.210
O33 Maternal care for known or suspected disproportion	0.790	0.210
I63 Cerebral infarction	0.790	0.210
Z88.5 Personal history of allergy to narcotic agent	0.791	0.209
O40 Polyhydramnios	0.791	0.209
H33 Retinal detachments and breaks	0.791	0.209
N89 Other noninflammatory disorders of vagina	0.791	0.209
O43 Placental disorders	0.791	0.209
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.791	0.209
O35 Maternal care for known or suspected foetal abnormality and damage	0.791	0.209
O41 Other disorders of amniotic fluid and membranes	0.791	0.209
O30 Multiple gestation	0.791	0.209
Z13 Special screening examination for other diseases and disorders	0.791	0.209
N98 Complications associated with artificial fertilisation	0.791	0.208
N96 Habitual aborter	0.791	0.208
O80 Single spontaneous delivery	0.791	0.208
N91 Absent, scanty and rare menstruation	0.792	0.208
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.792	0.208
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.792	0.208
O60 Preterm delivery	0.792	0.208
O74 Complications of anaesthesia during labour and delivery	0.792	0.208
N90 Other noninflammatory disorders of vulva and perineum	0.792	0.208
O65 Obstructed labour due to maternal pelvic abnormality	0.792	0.208
N82 Fistulae involving female genital tract	0.792	0.208
M23 Internal derangement of knee	0.792	0.208
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.792	0.208
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.792	0.208
O46 Antepartum haemorrhage, not elsewhere classified	0.792	0.207
O61 Failed induction of labour	0.792	0.207
N28 Other disorders of kidney and ureter, not elsewhere classified	0.792	0.208
B25-B34 Other viral diseases	0.792	0.207
O71 Other obstetric trauma	0.793	0.207
R47-R49 Symptoms and signs involving speech and voice	0.793	0.207
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.793	0.207
O66 Other obstructed labour	0.793	0.207
O64 Obstructed labour due to malposition and malpresentation of foetus	0.793	0.207
O20 Haemorrhage in early pregnancy	0.793	0.206
N19 Unspecified renal failure	0.793	0.206
Z04 Examination and observation for other reasons	0.793	0.206
N92 Excessive, frequent and irregular menstruation	0.794	0.206
I61 Intracerebral haemorrhage	0.794	0.206
O47 False labour	0.794	0.206
O69 Labour and delivery complicated by umbilical cord complications	0.794	0.206
B35-B49 Mycoses	0.794	0.205
I60 Subarachnoid haemorrhage	0.794	0.205
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.795	0.205
N75 Diseases of Bartholin's gland	0.795	0.205
O75 Other complications of labour and delivery, not elsewhere classified	0.795	0.205
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.795	0.205
N97 Female infertility	0.795	0.205
Z86.1 Personal history of infectious and parasitic diseases	0.795	0.205
E14 Unspecified diabetes mellitus	0.795	0.204
O34 Maternal care for known or suspected abnormality of pelvic organs	0.796	0.204
T15-T19 Effects of foreign body entering through natural orifice	0.796	0.204
N86 Erosion and ectropion of cervix uteri	0.796	0.204
N73 Other female pelvic inflammatory diseases	0.796	0.204
P90-P96 Other disorders originating in the perinatal period	0.796	0.204
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.796	0.204
P75-P78 Digestive system disorders of fetus and newborn	0.796	0.204
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.796	0.204
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.796	0.204
P35-P39 Infections specific to the perinatal period	0.796	0.204
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.796	0.204
P05-P08 Disorders related to length of gestation and fetal growth	0.796	0.204
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.796	0.204
P10-P15 Birth trauma	0.796	0.204
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.796	0.204
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.797	0.203
A75-A79 Rickettsioses	0.797	0.203
A70-A74 Other diseases caused by chlamydiae	0.797	0.203
A20-A28 Certain zoonotic bacterial diseases	0.797	0.203
B85-B89 Pediculosis, acariasis and other infestations	0.797	0.203
A65-A69 Other spirochaetal diseases	0.797	0.203
I08 Multiple valve diseases	0.797	0.203
O72 Postpartum haemorrhage	0.797	0.203
F43 Reaction to severe stress, and adjustment disorders	0.797	0.203
B99-B99 Other infectious diseases	0.797	0.203
A15-A19 Tuberculosis	0.797	0.203
B50-B64 Protozoal diseases	0.797	0.203
B65-B83 Helminthiases	0.797	0.203
B20-B24 Human immunodeficiency virus [HIV] disease	0.797	0.203
B90-B94 Sequelae of infectious and parasitic diseases	0.797	0.203
A80-A89 Viral infections of the central nervous system	0.797	0.203
A50-A64 Infections with a predominantly sexual mode of transmission	0.797	0.203
I68 Cerebrovascular disorders in diseases classified elsewhere	0.797	0.203
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.797	0.202
B15-B19 Viral hepatitis	0.798	0.202
S90-S99 Injuries to the ankle and foot	0.798	0.202
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.798	0.202
N71 Inflammatory disease of uterus, except cervix	0.799	0.201
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.799	0.201
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.799	0.201
D51 Vitamin B12 deficiency anaemia	0.799	0.200
R95-R99 Ill-defined and unknown causes of mortality	0.800	0.200
Z10 Routine general health check-up of defined subpopulation	0.800	0.200
G70-G73 Diseases of myoneural junction and muscle	0.800	0.200
H36 Retinal disorders in diseases classified elsewhere	0.800	0.200
G00-G09 Inflammatory diseases of the central nervous system	0.800	0.200
E12 Malnutrition-related diabetes mellitus	0.800	0.200
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.800	0.200
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.800	0.200
S00-S09 Injuries to the head	0.800	0.200
Z92.9 Personal history of medical treatment, unspecified	0.800	0.200
Z92.5 Personal history of rehabilitation measures	0.800	0.200
D70 Agranulocytosis	0.800	0.200
G90-G99 Other disorders of the nervous system	0.800	0.199
M25 Other joint disorders, not elsewhere classified	0.800	0.199
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.801	0.199
E13 Other specified diabetes mellitus	0.801	0.199
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.801	0.199
Z02 Examination and encounter for administrative purposes	0.801	0.199
G30-G32 Other degenerative diseases of the nervous system	0.801	0.199
N72 Inflammatory disease of cervix uteri	0.801	0.199
Z92.8 Personal history of other medical treatment	0.801	0.199
Z92.0 Personal history of contraception	0.801	0.199
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.801	0.199
F48 Other neurotic disorders	0.801	0.199
M13 Other arthritis	0.801	0.199
F44 Dissociative [conversion] disorders	0.801	0.198
Q20-Q28 Congenital malformations of the circulatory system	0.801	0.198
F42 Obsessive-compulsive disorder	0.801	0.198
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.802	0.198
O29 Complications of anaesthesia during pregnancy	0.802	0.198
O25 Malnutrition in pregnancy	0.802	0.198
E11.9 Without complications	0.802	0.198
O22 Venous complications in pregnancy	0.802	0.198
O28 Abnormal findings on antenatal screening of mother	0.802	0.198
I69 Sequelae of cerebrovascular disease	0.802	0.198
F45 Somatoform disorders	0.802	0.197
O24 Diabetes mellitus in pregnancy	0.802	0.197
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.802	0.197
O23 Infections of genito-urinary tract in pregnancy	0.802	0.197
O21 Excessive vomiting in pregnancy	0.802	0.197
D52 Folate deficiency anaemia	0.803	0.197
O04 Medical abortion	0.803	0.197
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.803	0.197
T79-T79 Certain early complications of trauma	0.803	0.197
F40 Phobic anxiety disorders	0.803	0.197
Q35-Q37 Cleft lip and cleft palate	0.803	0.197
Q30-Q34 Congenital malformations of the respiratory system	0.803	0.197
Z08 Follow-up examination after treatment for malignant neoplasm	0.803	0.197
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.803	0.197
I10 Essential (primary) hypertension	0.803	0.197
Z72.1 Alcohol use	0.803	0.197
M79 Other soft tissue disorders, not elsewhere classified	0.803	0.197
Z92.6 Personal history of chemotherapy for neoplastic disease	0.803	0.197
O02 Other abnormal products of conception	0.803	0.197
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.803	0.196
G35-G37 Demyelinating diseases of the central nervous system	0.803	0.196
Q00-Q07 Congenital malformations of the nervous system	0.803	0.196
I95 Hypotension	0.803	0.196
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.804	0.196
J22 Unspecified acute lower respiratory infection	0.804	0.196
G80-G83 Cerebral palsy and other paralytic syndromes	0.804	0.196
N17 Acute renal failure	0.804	0.196
Q80-Q89 Other congenital malformations	0.804	0.196
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.804	0.196
G20-G26 Extrapyramidal and movement disorders	0.804	0.196
Q38-Q45 Other congenital malformations of the digestive system	0.804	0.195
Q50-Q56 Congenital malformations of genital organs	0.804	0.195
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.804	0.195
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.804	0.195
E87 Other disorders of fluid, electrolyte and acid-base balance	0.805	0.195
B95-B98 Bacterial, viral and other infectious agents	0.805	0.195
Z72.0 Tobacco use	0.805	0.195
N85 Other noninflammatory disorders of uterus, except cervix	0.805	0.195
N03 Chronic nephritic syndrome	0.805	0.195
Q60-Q64 Congenital malformations of the urinary system	0.805	0.195
N18.3 Chronic kidney disease, stage 3	0.805	0.195
N70 Salpingitis and oophoritis	0.805	0.195
S50-S59 Injuries to the elbow and forearm	0.806	0.194
T33-T35 Frostbite	0.806	0.194
T26-T28 Burns and corrosions confined to eye and internal organs	0.806	0.194
F18 Mental and behavioural disorders due to use of volatile solvents	0.806	0.194
F16 Mental and behavioural disorders due to use of hallucinogens	0.806	0.194
F14 Mental and behavioural disorders due to use of cocaine	0.806	0.194
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.806	0.194
N76 Other inflammation of vagina and vulva	0.806	0.194
S80-S89 Injuries to the knee and lower leg	0.806	0.194
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.806	0.194
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.806	0.194
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.806	0.194
T00-T07 Injuries involving multiple body regions	0.806	0.193
F11 Mental and behavioural disorders due to use of opioids	0.806	0.193
S40-S49 Injuries to the shoulder and upper arm	0.806	0.193
F12 Mental and behavioural disorders due to use of cannabinoids	0.806	0.193
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.807	0.193
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.807	0.193
N27 Small kidney of unknown cause	0.807	0.193
O84 Multiple delivery	0.807	0.193
O83 Other assisted single delivery	0.807	0.193
N25 Disorders resulting from impaired renal tubular function	0.807	0.193
H32 Chorioretinal disorders in diseases classified elsewhere	0.807	0.193
I80 Phlebitis and thrombophlebitis	0.807	0.193
N26 Unspecified contracted kidney	0.807	0.193
H30 Chorioretinal inflammation	0.807	0.193
M35 Other systemic involvement of connective tissue	0.807	0.193
H91 Other hearing loss	0.807	0.193
Z86.6 Personal history of diseases of the nervous system and sense organs	0.807	0.192
O81 Single delivery by forceps and vacuum extractor	0.807	0.192
T20-T25 Burns and corrosions of external body surface, specified by site	0.807	0.192
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.807	0.192
S10-S19 Injuries to the neck	0.807	0.192
Z03 Medical observation and evaluation for suspected diseases and conditions	0.808	0.192
H31 Other disorders of choroid	0.808	0.192
M32 Systemic lupus erythematosus	0.808	0.192
M30 Polyarteritis nodosa and related conditions	0.808	0.192
M33 Dermatopolymyositis	0.808	0.192
G50-G59 Nerve, nerve root and plexus disorders	0.808	0.192
D53 Other nutritional anaemias	0.808	0.192
F03 Unspecified dementia	0.808	0.192
I28 Other diseases of pulmonary vessels	0.808	0.192
M34 Systemic sclerosis	0.808	0.192
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.808	0.191
Z36.0 Antenatal screening for chromosomal anomalies	0.808	0.191
I20 Angina pectoris	0.809	0.191
O82 Single delivery by Caesarean section	0.809	0.191
F01 Vascular dementia	0.809	0.191
H34 Retinal vascular occlusions	0.809	0.191
T66-T78 Other and unspecified effects of external causes	0.809	0.191
M81 Osteoporosis without pathological fracture	0.809	0.191
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.809	0.191
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.809	0.191
A30-A49 Other bacterial diseases	0.809	0.191
O86 Other puerperal infections	0.809	0.190
M31 Other necrotising vasculopathies	0.809	0.190
J44 Other chronic obstructive pulmonary disease	0.809	0.190
Z63 Other problems related to primary support group, including family circumstances	0.809	0.190
E83 Disorders of mineral metabolism	0.810	0.190
O05 Other abortion	0.810	0.190
O07 Failed attempted abortion	0.810	0.190
O06 Unspecified abortion	0.810	0.190
O01 Hydatidiform mole	0.810	0.190
M21 Other acquired deformities of limbs	0.810	0.190
I77 Other disorders of arteries and arterioles	0.810	0.190
O08 Complications following abortion and ectopic and molar pregnancy	0.810	0.189
M22 Disorders of patella	0.810	0.189
Z87 Personal history of other diseases and conditions	0.811	0.189
S70-S79 Injuries to the hip and thigh	0.811	0.189
F52 Sexual dysfunction, not caused by organic disorder or disease	0.811	0.189
I27 Other pulmonary heart diseases	0.811	0.189
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.811	0.189
H92 Otalgia and effusion of ear	0.811	0.189
O00 Ectopic pregnancy	0.811	0.189
H93 Other disorders of ear, not elsewhere classified	0.811	0.188
D72 Other disorders of white blood cells	0.812	0.188
N95.8 Other specified menopausal and perimenopausal disorders	0.812	0.188
C60-C63 Malignant neoplasms of male genital organs	0.812	0.188
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.812	0.188
N18.9 Chronic renal failure, unspecified	0.812	0.188
F17 Mental and behavioural disorders due to use of tobacco	0.812	0.188

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations