TreeWAS – Variant ID: rs4517962

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J33 Nasal polyp	0.000	0.000	1.000
J33.8 Other polyp of sinus	0.000	0.000	1.000
J33.0 Polyp of nasal cavity	0.000	0.000	1.000
J33.9 Nasal polyp, unspecified	0.000	0.008	0.992
I25 Chronic ischaemic heart disease	0.977	0.023	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.967	0.033	0.000
I25.2 Old myocardial infarction	0.947	0.053	0.000
I20-I25 Ischaemic heart diseases	0.943	0.057	0.000
I20 Angina pectoris	0.939	0.061	0.000
I20.0 Unstable angina	0.933	0.067	0.000
I25.1 Atherosclerotic heart disease	0.911	0.089	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.895	0.105	0.000
I20.9 Angina pectoris, unspecified	0.864	0.136	0.000
I21 Acute myocardial infarction	0.853	0.147	0.000
I21.9 Acute myocardial infarction, unspecified	0.824	0.176	0.000
I25.3 Aneurysm of heart	0.784	0.216	0.000
I25.6 Silent myocardial ischaemia	0.764	0.236	0.000
I20.1 Angina pectoris with documented spasm	0.760	0.240	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.746	0.254	0.000
I25.5 Ischaemic cardiomyopathy	0.744	0.256	0.000
I25.4 Coronary artery aneurysm	0.700	0.300	0.000
I21.4 Acute subendocardial myocardial infarction	0.697	0.303	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.693	0.307	0.000
I23 Certain current complications following acute myocardial infarction	0.683	0.317	0.000
J33.1 Polypoid sinus degeneration	0.000	0.320	0.680
I21.3 Acute transmural myocardial infarction of unspecified site	0.623	0.377	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.612	0.388	0.000
I23.8 Other current complications following acute myocardial infarction	0.496	0.503	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.490	0.510	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.490	0.510	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.490	0.510	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.490	0.510	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.490	0.510	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.490	0.510	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.490	0.510	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.450	0.550	0.000
I24 Other acute ischaemic heart diseases	0.312	0.688	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.711	0.289
I08 Multiple valve diseases	0.287	0.713	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.282	0.718	0.000
I05-I09 Chronic rheumatic heart diseases	0.276	0.723	0.000
I05 Rheumatic mitral valve diseases	0.272	0.728	0.000
I08.0 Disorders of both mitral and aortic valves	0.270	0.730	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.733	0.267
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.738	0.262
J30.3 Other allergic rhinitis	0.000	0.739	0.261
I22 Subsequent myocardial infarction	0.260	0.740	0.000
I08.8 Other multiple valve diseases	0.259	0.741	0.000
I05.0 Mitral stenosis	0.252	0.748	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.244	0.756	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.757	0.243
I20.8 Other forms of angina pectoris	0.239	0.761	0.000
J31.0 Chronic rhinitis	0.000	0.766	0.234
Chapter IX Diseases of the circulatory system	0.234	0.766	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.772	0.228
I05.9 Mitral valve disease, unspecified	0.227	0.773	0.000
I05.8 Other mitral valve diseases	0.220	0.780	0.000
J30.0 Vasomotor rhinitis	0.000	0.780	0.220
I05.1 Rheumatic mitral insufficiency	0.217	0.783	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.217	0.783	0.000
J38.4 Oedema of larynx	0.000	0.786	0.214
J38.3 Other diseases of vocal cords	0.000	0.786	0.214
I05.2 Mitral stenosis with insufficiency	0.206	0.794	0.000
J31.1 Chronic nasopharyngitis	0.000	0.796	0.204
I09 Other rheumatic heart diseases	0.198	0.802	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.198	0.802	0.000
J31.2 Chronic pharyngitis	0.000	0.805	0.194
J38.5 Laryngeal spasm	0.000	0.806	0.194
J38.2 Nodules of vocal cords	0.000	0.806	0.194
I22.1 Subsequent myocardial infarction of inferior wall	0.192	0.807	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.808	0.192
I00-I02 Acute rheumatic fever	0.186	0.814	0.000
I24.1 Dressler's syndrome	0.186	0.814	0.000
J37.0 Chronic laryngitis	0.000	0.815	0.185
I06 Rheumatic aortic valve diseases	0.184	0.816	0.000
J39 Other diseases of upper respiratory tract	0.000	0.817	0.183
J38.1 Polyp of vocal cord and larynx	0.000	0.820	0.180
J30.4 Allergic rhinitis, unspecified	0.000	0.821	0.179
I22.0 Subsequent myocardial infarction of anterior wall	0.173	0.826	0.000
I74 Arterial embolism and thrombosis	0.170	0.830	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.169	0.831	0.000
I08.9 Multiple valve disease, unspecified	0.168	0.832	0.000
J39.2 Other diseases of pharynx	0.000	0.835	0.165
I74.5 Embolism and thrombosis of iliac artery	0.164	0.836	0.000
J37.1 Chronic laryngotracheitis	0.000	0.836	0.164
J38.6 Stenosis of larynx	0.000	0.844	0.156
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.152	0.848	0.000
I00 Rheumatic fever without mention of heart involvement	0.151	0.849	0.000
I24.8 Other forms of acute ischaemic heart disease	0.147	0.853	0.000
I09.8 Other specified rheumatic heart diseases	0.142	0.858	0.000
I09.2 Chronic rheumatic pericarditis	0.142	0.858	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.142	0.858	0.000
I09.0 Rheumatic myocarditis	0.142	0.858	0.000
I09.9 Rheumatic heart disease, unspecified	0.142	0.858	0.000
I74.8 Embolism and thrombosis of other arteries	0.141	0.859	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.136	0.864	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.866	0.134
I02 Rheumatic chorea	0.133	0.867	0.000
I01 Rheumatic fever with heart involvement	0.133	0.867	0.000
J34 Other disorders of nose and nasal sinuses	0.000	0.867	0.133
I06.9 Rheumatic aortic valve disease, unspecified	0.132	0.868	0.000
I06.8 Other rheumatic aortic valve diseases	0.132	0.868	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.132	0.868	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.132	0.868	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.131	0.869	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.869	0.131
J39.1 Other abscess of pharynx	0.000	0.869	0.131
I06.1 Rheumatic aortic insufficiency	0.125	0.874	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.125	0.874	0.000
I06.0 Rheumatic aortic stenosis	0.125	0.875	0.000
I71 Aortic aneurysm and dissection	0.124	0.876	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.124	0.876	0.000
I07 Rheumatic tricuspid valve diseases	0.123	0.876	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.113	0.887	0.000
I71.0 Dissection of aorta [any part]	0.112	0.888	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.890	0.110
J36 Peritonsillar abscess	0.000	0.895	0.105
J38.0 Paralysis of vocal cords and larynx	0.000	0.895	0.105
I77 Other disorders of arteries and arterioles	0.101	0.899	0.000
I73 Other peripheral vascular diseases	0.100	0.900	0.000
I70 Atherosclerosis	0.099	0.901	0.000
J34.2 Deviated nasal septum	0.000	0.902	0.098
I22.8 Subsequent myocardial infarction of other sites	0.097	0.903	0.001
J38.7 Other diseases of larynx	0.000	0.904	0.096
I01.9 Acute rheumatic heart disease, unspecified	0.096	0.904	0.000
I01.8 Other acute rheumatic heart disease	0.096	0.904	0.000
I01.2 Acute rheumatic myocarditis	0.096	0.904	0.000
I01.1 Acute rheumatic endocarditis	0.096	0.904	0.000
I01.0 Acute rheumatic pericarditis	0.096	0.904	0.000
I02.9 Rheumatic chorea without heart involvement	0.096	0.904	0.000
I02.0 Rheumatic chorea with heart involvement	0.096	0.904	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.095	0.905	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.092	0.908	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.089	0.911	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.089	0.911	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.089	0.911	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.089	0.911	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.089	0.911	0.000
I79.1 Aortitis in diseases classified elsewhere	0.089	0.911	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.089	0.911	0.000
I07.9 Tricuspid valve disease, unspecified	0.088	0.911	0.001
I07.8 Other tricuspid valve diseases	0.088	0.911	0.001
I07.2 Tricuspid stenosis with insufficiency	0.088	0.911	0.001
I07.0 Tricuspid stenosis	0.088	0.911	0.001
I73.9 Peripheral vascular disease, unspecified	0.087	0.913	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.914	0.086
I21.1 Acute transmural myocardial infarction of inferior wall	0.083	0.917	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.001	0.917	0.082
J34.3 Hypertrophy of nasal turbinates	0.000	0.918	0.082
I77.0 Arteriovenous fistula, acquired	0.080	0.920	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.077	0.923	0.000
I77.8 Other specified disorders of arteries and arterioles	0.077	0.923	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.073	0.927	0.000
I77.5 Necrosis of artery	0.073	0.927	0.000
I77.4 Coeliac artery compression syndrome	0.073	0.927	0.000
I77.3 Arterial fibromuscular dysplasia	0.073	0.927	0.000
I77.1 Stricture of artery	0.071	0.929	0.000
I70.8 Atherosclerosis of other arteries	0.070	0.930	0.000
I73.8 Other specified peripheral vascular diseases	0.069	0.931	0.000
I70.1 Atherosclerosis of renal artery	0.068	0.932	0.000
I70.9 Generalised and unspecified atherosclerosis	0.067	0.933	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.066	0.934	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.065	0.935	0.000
I77.2 Rupture of artery	0.064	0.936	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.063	0.936	0.001
J32 Chronic sinusitis	0.000	0.937	0.063
J39.8 Other specified diseases of upper respiratory tract	0.000	0.938	0.062
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.062	0.938	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.062	0.938	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.941	0.059
I70.0 Atherosclerosis of aorta	0.057	0.942	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.057	0.943	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.056	0.944	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.055	0.945	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.054	0.945	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.946	0.054
I97.1 Other functional disturbances following cardiac surgery	0.051	0.949	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.050	0.949	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.050	0.950	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.049	0.951	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.048	0.952	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.046	0.954	0.000
J32.1 Chronic frontal sinusitis	0.000	0.954	0.046
G56.0 Carpal tunnel syndrome	0.046	0.954	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.045	0.955	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.043	0.956	0.000
I78 Diseases of capillaries	0.043	0.957	0.000
I28 Other diseases of pulmonary vessels	0.042	0.957	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.041	0.958	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.041	0.959	0.000
I97.0 Postcardiotomy syndrome	0.041	0.959	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.040	0.959	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.040	0.959	0.000
I72 Other aneurysm	0.040	0.960	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.961	0.039
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.038	0.962	0.000
I10-I15 Hypertensive diseases	0.036	0.964	0.000
I77.6 Arteritis, unspecified	0.035	0.965	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.967	0.033
J32.3 Chronic sphenoidal sinusitis	0.000	0.968	0.032
I28.9 Disease of pulmonary vessels, unspecified	0.030	0.969	0.001
I28.1 Aneurysm of pulmonary artery	0.030	0.969	0.001
I28.0 Arteriovenous fistula of pulmonary vessels	0.030	0.969	0.001
I78.9 Disease of capillaries, unspecified	0.031	0.969	0.000
I99 Other and unspecified disorders of circulatory system	0.029	0.971	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.029	0.971	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.029	0.971	0.000
I72.1 Aneurysm of artery of upper extremity	0.028	0.972	0.000
I28.8 Other specified diseases of pulmonary vessels	0.027	0.972	0.001
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.972	0.028
I70.00 Atherosclerosis of aorta (without gangrene)	0.028	0.972	0.000
I13 Hypertensive heart and renal disease	0.027	0.972	0.000
J35.2 Hypertrophy of adenoids	0.000	0.973	0.027
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.973	0.027
I72.9 Aneurysm of unspecified site	0.027	0.973	0.000
I15 Secondary hypertension	0.026	0.974	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.026	0.974	0.000
I72.3 Aneurysm of iliac artery	0.026	0.974	0.000
I72.2 Aneurysm of renal artery	0.025	0.974	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.975	0.025
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.975	0.025
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.975	0.025
I26 Pulmonary embolism	0.024	0.976	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.976	0.024
J32.4 Chronic pansinusitis	0.000	0.976	0.024
I73.0 Raynaud's syndrome	0.023	0.976	0.000
I72.8 Aneurysm of other specified arteries	0.023	0.977	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.022	0.978	0.000
J32.8 Other chronic sinusitis	0.000	0.978	0.022
I15.0 Renovascular hypertension	0.022	0.978	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.021	0.978	0.000
I72.4 Aneurysm of artery of lower extremity	0.021	0.979	0.000
I15.2 Hypertension secondary to endocrine disorders	0.021	0.979	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.979	0.021
I78.8 Other diseases of capillaries	0.020	0.979	0.000
R10.0 Acute abdomen	0.021	0.979	0.000
I72.0 Aneurysm of carotid artery	0.020	0.980	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.980	0.020
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.020	0.980	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.020	0.980	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.020	0.980	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.980	0.020
J32.9 Chronic sinusitis, unspecified	0.000	0.980	0.020
I27 Other pulmonary heart diseases	0.015	0.981	0.004
I15.8 Other secondary hypertension	0.019	0.981	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.019	0.981	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.019	0.981	0.000
I98.0 Cardiovascular syphilis	0.019	0.981	0.000
I15.1 Hypertension secondary to other renal disorders	0.018	0.982	0.000
I27.0 Primary pulmonary hypertension	0.000	0.983	0.017
J35.1 Hypertrophy of tonsils	0.000	0.983	0.017
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.983	0.017
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.016	0.984	0.001
I78.1 Naevus, nonneoplastic	0.016	0.984	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.984	0.016
I07.1 Tricuspid insufficiency	0.012	0.985	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.985	0.015
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.014	0.985	0.000
I27.8 Other specified pulmonary heart diseases	0.012	0.986	0.002
I27.1 Kyphoscoliotic heart disease	0.011	0.986	0.003
I12 Hypertensive renal disease	0.014	0.986	0.000
I11 Hypertensive heart disease	0.013	0.986	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.012
I15.9 Seconday hypertension, unspecified	0.012	0.988	0.000
I27.9 Pulmonary heart disease, unspecified	0.009	0.988	0.003
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.990	0.010
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.991	0.009
I98.2 Oesophageal varices in diseases classified elsewhere	0.009	0.991	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.991	0.009
I12.9 Hypertensive renal disease without renal failure	0.009	0.991	0.000
S00.0 Superficial injury of scalp	0.009	0.991	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.992	0.008
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.992	0.008
C49.5 Connective and soft tissue of pelvis	0.000	0.992	0.007
C49.9 Connective and soft tissue, unspecified	0.000	0.993	0.007
I11.0 Hypertensive heart disease with (congestive) heart failure	0.007	0.993	0.001
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.993	0.007
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.993	0.007
C49.4 Connective and soft tissue of abdomen	0.000	0.993	0.007
I27.2 Other secondary pulmonary hypertension	0.003	0.993	0.003
R23.4 Changes in skin texture	0.007	0.993	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.993	0.007
J35.0 Chronic tonsillitis	0.000	0.994	0.006
O97 Death from sequelae of direct obstetric causes	0.000	0.994	0.006
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.994	0.006
O95 Obstetric death of unspecified cause	0.000	0.994	0.006
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.994	0.006
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.994	0.006
D04.4 Skin of scalp and neck	0.000	0.995	0.005
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.995	0.005
D04.5 Skin of trunk	0.000	0.995	0.005
I49.3 Ventricular premature depolarisation	0.000	0.995	0.005
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.995	0.005
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
S22.30 Fracture of rib (closed)	0.005	0.995	0.000
D04 Carcinoma in situ of skin	0.000	0.995	0.005
M86.9 Osteomyelitis, unspecified	0.000	0.995	0.005
I11.9 Hypertensive heart disease without (congestive) heart failure	0.004	0.995	0.001
D04.6 Skin of upper limb, including shoulder	0.000	0.995	0.005
S22.00 Fracture of thoracic vertebra (closed)	0.005	0.995	0.000
O96.9 Death from unspecified obstetric cause	0.000	0.995	0.004
O96.1 Death from indirect obstetric cause	0.000	0.995	0.004
O96.0 Death from direct obstetric cause	0.000	0.995	0.004
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.995	0.004
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.995	0.004
O97.0 Death from sequelae of direct obstetric cause	0.000	0.995	0.004
I95 Hypotension	0.005	0.995	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.005	0.995	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
S22.3 Fracture of rib	0.004	0.996	0.000
S22.0 Fracture of thoracic vertebra	0.004	0.996	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.996	0.004
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
H10.9 Conjunctivitis, unspecified	0.004	0.996	0.000
D04.9 Skin, unspecified	0.000	0.996	0.004
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
D04.7 Skin of lower limb, including hip	0.000	0.996	0.004
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.996	0.004
S22.1 Multiple fractures of thoracic spine	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
D04.8 Skin of other sites	0.000	0.996	0.004
D04.0 Skin of lip	0.000	0.996	0.004
R23.3 Spontaneous ecchymoses	0.004	0.996	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.996	0.004
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.996	0.004
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.996	0.004
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.996	0.004
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
G56 Mononeuropathies of upper limb	0.004	0.996	0.000
S00 Superficial injury of head	0.004	0.996	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.996	0.004
O71.4 Obstetric high vaginal laceration alone	0.004	0.996	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.996	0.003
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
S22.31 Fracture of rib (open)	0.003	0.997	0.000
S00.9 Superficial injury of head, part unspecified	0.003	0.997	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
S22.01 Fracture of thoracic vertebra (open)	0.003	0.997	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.003	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.000	0.997	0.003
I95.0 Idiopathic hypotension	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.003	0.997	0.000
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
I60-I69 Cerebrovascular diseases	0.003	0.997	0.000
S00.5 Superficial injury of lip and oral cavity	0.003	0.997	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.003	0.997	0.000
Z37.2 Twins, both liveborn	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
R23 Other skin changes	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.997	0.000
S00.3 Superficial injury of nose	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
G56.4 Causalgia	0.003	0.997	0.000
Z88.2 Personal history of allergy to sulphonamides	0.000	0.997	0.003
H10 Conjunctivitis	0.003	0.997	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.003	0.997	0.000
H10.3 Acute conjunctivitis, unspecified	0.003	0.997	0.000
I95.8 Other hypotension	0.003	0.997	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.003	0.997	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.003	0.997	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.997	0.002
D61 Other aplastic anaemias	0.000	0.997	0.003
Z43 Attention to artificial openings	0.000	0.997	0.003
T42.3 Barbiturates	0.003	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
G56.1 Other lesions of median nerve	0.002	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.002	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.997	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.997	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.997	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.997	0.000
Z43.2 Attention to ileostomy	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.002	0.997	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.003	0.997	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
Y40.0 Penicillins	0.000	0.997	0.003
Z86.6 Personal history of diseases of the nervous system and sense organs	0.000	0.997	0.003
C62.9 Testis, unspecified	0.002	0.997	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.002	0.997	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.002	0.997	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.002	0.998	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.002	0.998	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.002	0.998	0.000
S00.4 Superficial injury of ear	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.998	0.002
R23.2 Flushing	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.998	0.000
V23.5 Passenger injured in traffic accident	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
G56.3 Lesion of radial nerve	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
G40.9 Epilepsy, unspecified	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.998	0.002
D61.0 Constitutional aplastic anaemia	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
Z43.9 Attention to unspecified artificial opening	0.000	0.998	0.002
Z43.7 Attention to artificial vagina	0.000	0.998	0.002
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
O71 Other obstetric trauma	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
Z43.0 Attention to tracheostomy	0.000	0.998	0.002
I95.2 Hypotension due to drugs	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
V23.9 Unspecified motorcycle rider injured in traffic accident	0.002	0.998	0.000
V23.3 Person injured while boarding or alighting	0.002	0.998	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.002	0.998	0.000
V23.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
V23.0 Driver injured in nontraffic accident	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Z43.5 Attention to cyctostomy	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.002	0.998	0.000
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.002	0.998	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Z43.8 Attention to other artificial openings	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
R23.0 Cyanosis	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.002	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.998	0.000
J17.2 Pneumonia in mycoses	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
R40.2 Coma, unspecified	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.998	0.002
J17.1 Pneumonia in viral diseases classified elsewhere	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.998	0.000
O71.3 Obstetric laceration of cervix	0.002	0.998	0.000
O71.2 Postpartum inversion of uterus	0.002	0.998	0.000
O71.1 Rupture of uterus during labour	0.002	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations