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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45520142
log Bayes Factor = 10.8117
Chromosome 14   position 30,149,560  (GRCh37) Explore rs45520142 on Ensembl!
Variant rs45520142 is part of Cluster X0193

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.997 0.003 0.000
J30-J39 Other diseases of upper respiratory tract
0.996 0.004 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.974 0.026 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.973 0.027 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.972 0.028 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.972 0.028 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.965 0.035 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.965 0.035 0.000
S20-S29 Injuries to the thorax
0.958 0.042 0.000
J38.4 Oedema of larynx
0.958 0.042 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.956 0.044 0.000
J38.7 Other diseases of larynx
0.951 0.049 0.000
M45-M49 Spondylopathies
0.936 0.064 0.000
J00-J06 Acute upper respiratory infections
0.929 0.071 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.928 0.072 0.000
G62 Other polyneuropathies
0.926 0.074 0.000
M50-M54 Other dorsopathies
0.925 0.075 0.000
F03 Unspecified dementia
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.920 0.079 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
T18 Foreign body in alimentary tract
0.911 0.089 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.910 0.090 0.000
J60-J70 Lung diseases due to external agents
0.909 0.091 0.000
G90-G99 Other disorders of the nervous system
0.903 0.097 0.000
M86-M90 Other osteopathies
0.898 0.102 0.000
S90-S99 Injuries to the ankle and foot
0.896 0.104 0.000
J39 Other diseases of upper respiratory tract
0.895 0.105 0.000
T42.4 Benzodiazepines
0.895 0.105 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.895 0.105 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.893 0.107 0.000
E70-E90 Metabolic disorders
0.888 0.112 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.883 0.117 0.000
M24 Other specific joint derangements
0.882 0.118 0.000
T17 Foreign body in respiratory tract
0.881 0.119 0.000
M51 Other intervertebral disk disorders
0.881 0.119 0.000
F00 Dementia in Alzheimer's disease
0.880 0.120 0.000
E87.6 Hypokalaemia
0.879 0.121 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.879 0.121 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.878 0.122 0.000
G58 Other mononeuropathies
0.877 0.123 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.876 0.124 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.872 0.128 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.870 0.130 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.870 0.130 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.869 0.131 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.868 0.132 0.000
J38.0 Paralysis of vocal cords and larynx
0.864 0.136 0.000
X60-X84 Intentional self-harm
0.860 0.140 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.859 0.141 0.000
G62.9 Polyneuropathy, unspecified
0.856 0.144 0.000
V10-V19 Pedal cyclist injured in transport accident
0.853 0.147 0.000
G30-G32 Other degenerative diseases of the nervous system
0.851 0.149 0.000
S20 Superficial injury of thorax
0.850 0.150 0.000
F01 Vascular dementia
0.850 0.150 0.000
S60-S69 Injuries to the wrist and hand
0.849 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.846 0.154 0.000
J69 Pneumonitis due to solids and liquids
0.846 0.154 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.844 0.156 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.843 0.157 0.000
G51 Facial nerve disorders
0.840 0.160 0.000
M45 Ankylosing spondylitis
0.837 0.163 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.835 0.165 0.000
J00 Acute nasopharyngitis [common cold]
0.834 0.166 0.000
T18.1 Foreign body in oesophagus
0.833 0.167 0.000
J20-J22 Other acute lower respiratory infections
0.833 0.167 0.000
T93 Sequelae of injuries of lower limb
0.830 0.170 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.829 0.171 0.000
Chapter XXII Codes for special purposes
0.828 0.172 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.827 0.173 0.000
M47 Spondylosis
0.824 0.176 0.000
T79-T79 Certain early complications of trauma
0.822 0.178 0.000
J37 Chronic laryngitis and laryngotracheitis
0.821 0.179 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.819 0.181 0.000
V80-V89 Other land transport accidents
0.819 0.181 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.816 0.184 0.000
J30 Vasomotor and allergic rhinitis
0.815 0.185 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.814 0.186 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.812 0.188 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.812 0.188 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.811 0.189 0.000
T40.2 Other opioids
0.809 0.191 0.000
M05 Seropositive rheumatoid arthritis
0.808 0.192 0.000
M89 Other disorders of bone
0.808 0.192 0.000
G91 Hydrocephalus
0.807 0.193 0.000
D70 Agranulocytosis
0.807 0.193 0.000
T90 Sequelae of injuries of head
0.807 0.193 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.807 0.193 0.000
M24.1 Other articular cartilage disorders
0.806 0.194 0.000
G58.8 Other specified mononeuropathies
0.806 0.194 0.000
J02 Acute pharyngitis
0.805 0.195 0.000
S68 Traumatic amputation of wrist and hand
0.802 0.198 0.000
J69.0 Pneumonitis due to food and vomit
0.801 0.199 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.800 0.200 0.000
J39.2 Other diseases of pharynx
0.799 0.201 0.000
J31.0 Chronic rhinitis
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.794 0.206 0.000
T43.2 Other and unspecified antidepressants
0.793 0.207 0.000
T66-T78 Other and unspecified effects of external causes
0.792 0.208 0.000
G62.8 Other specified polyneuropathies
0.792 0.208 0.000
V40-V49 Car occupant injured in transport accident
0.792 0.208 0.000
M06.3 Rheumatoid nodule
0.791 0.209 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.790 0.210 0.000
Q23 Congenital malformations of aortic and mitral valves
0.789 0.211 0.000
S91 Open wound of ankle and foot
0.789 0.211 0.000
J33 Nasal polyp
0.787 0.213 0.000
J38.1 Polyp of vocal cord and larynx
0.787 0.213 0.000
G60 Hereditary and idiopathic neuropathy
0.787 0.213 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.786 0.214 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.785 0.215 0.000
G54 Nerve root and plexus disorders
0.784 0.216 0.000
W20-W49 Exposure to inanimate mechanical forces
0.781 0.219 0.000
T17.2 Foreign body in pharynx
0.781 0.219 0.000
M51.9 Intervertebral disk disorder, unspecified
0.780 0.220 0.000
M54 Dorsalgia
0.780 0.220 0.000
M12 Other specific arthropathies
0.779 0.221 0.000
J38.2 Nodules of vocal cords
0.778 0.221 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.778 0.222 0.000
M47.8 Other spondylosis
0.777 0.223 0.000
V70-V79 Bus occupant injured in transport accident
0.774 0.225 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.774 0.226 0.000
T98 Sequelae of other and unspecified effects of external causes
0.769 0.231 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.769 0.231 0.000
T00-T07 Injuries involving multiple body regions
0.768 0.232 0.000
X20-X29 Contact with venomous animals and plants
0.768 0.232 0.000
T91 Sequelae of injuries of neck and trunk
0.767 0.233 0.000
E00-E07 Disorders of thyroid gland
0.765 0.235 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.764 0.236 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.764 0.236 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.764 0.236 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.763 0.237 0.000
T39.0 Salicylates
0.763 0.237 0.000
F01.9 Vascular dementia, unspecified
0.762 0.238 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.761 0.239 0.000
M20 Acquired deformities of fingers and toes
0.758 0.242 0.000
J95-J99 Other diseases of the respiratory system
0.758 0.242 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.757 0.243 0.000
J01 Acute sinusitis
0.756 0.244 0.000
F02 Dementia in other diseases classified elsewhere
0.755 0.245 0.000
D75 Other diseases of blood and blood-forming organs
0.755 0.245 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
S21 Open wound of thorax
0.753 0.247 0.000
G57 Mononeuropathies of lower limb
0.752 0.248 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.751 0.248 0.000
W50-W64 Exposure to animate mechanical forces
0.751 0.248 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.749 0.251 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.749 0.251 0.000
M89.8 Other specified disorders of bone
0.746 0.254 0.000
M40-M43 Deforming dorsopathies
0.744 0.256 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.744 0.256 0.000
G30 Alzheimer's disease
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.741 0.259 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.260 0.000
M51.2 Other specified intervertebral disk displacement
0.740 0.260 0.000
T92 Sequelae of injuries of upper limb
0.739 0.261 0.000
E87.3 Alkalosis
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.737 0.262 0.000
D69 Purpura and other haemorrhagic conditions
0.737 0.263 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
F06.7 Mild cognitive disorder
0.737 0.263 0.000
E85 Amyloidosis
0.736 0.264 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.735 0.265 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.734 0.266 0.000
J22 Unspecified acute lower respiratory infection
0.732 0.268 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.732 0.268 0.000
G51.0 Bell's palsy
0.731 0.269 0.000
S64 Injury of nerves at wrist and hand level
0.728 0.272 0.000
Q23.1 Congenital insufficiency of aortic valve
0.727 0.273 0.000
T18.5 Foreign body in anus and rectum
0.727 0.273 0.000
J38.3 Other diseases of vocal cords
0.726 0.274 0.000
M47.86 Other spondylosis (Lumbar region)
0.726 0.274 0.000
G63.2 Diabetic polyneuropathy
0.726 0.274 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.725 0.275 0.000
W00-W19 Falls
0.724 0.276 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.723 0.276 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.722 0.278 0.000
G91.9 Hydrocephalus, unspecified
0.722 0.278 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.721 0.279 0.000
Q27 Other congenital malformations of peripheral vascular system
0.720 0.280 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.719 0.280 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.719 0.280 0.000
M21 Other acquired deformities of limbs
0.719 0.281 0.000
X50-X57 Overexertion, travel and privation
0.718 0.282 0.000
G35 Multiple sclerosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.717 0.283 0.000
J02.9 Acute pharyngitis, unspecified
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.715 0.284 0.000
M06.2 Rheumatoid bursitis
0.715 0.284 0.000
M06.1 Adult-onset Still's disease
0.715 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.284 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.715 0.284 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.715 0.284 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.715 0.285 0.000
J30.4 Allergic rhinitis, unspecified
0.713 0.287 0.000
J38.6 Stenosis of larynx
0.713 0.287 0.000
J38.5 Laryngeal spasm
0.713 0.287 0.000
S20.2 Contusion of thorax
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.712 0.288 0.000
T14 Injury of unspecified body region
0.712 0.288 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.711 0.289 0.000
T18.9 Foreign body in alimentary tract, part unspecified
0.710 0.289 0.000
G90 Disorders of autonomic nervous system
0.710 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.290 0.000
S22.2 Fracture of sternum
0.708 0.292 0.000
G56 Mononeuropathies of upper limb
0.707 0.293 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.707 0.293 0.000
M20.4 Other hammer toe(s) (acquired)
0.707 0.293 0.000
Y40 Systemic antibiotics
0.706 0.294 0.000
J39.8 Other specified diseases of upper respiratory tract
0.706 0.294 0.000
G96 Other disorders of central nervous system
0.705 0.295 0.000
D68 Other coagulation defects
0.705 0.295 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.704 0.295 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.703 0.297 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.703 0.297 0.000
S80-S89 Injuries to the knee and lower leg
0.702 0.298 0.000
M51.8 Other specified intervertebral disk disorders
0.702 0.298 0.000
E50-E64 Other nutritional deficiencies
0.702 0.298 0.000
M24.6 Ankylosis of joint
0.701 0.299 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.700 0.300 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.700 0.300 0.000
S92 Fracture of foot, except ankle
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
F70-F79 Mental retardation
0.699 0.301 0.000
G95 Other diseases of spinal cord
0.699 0.301 0.000
T43.9 Psychotropic drug, unspecified
0.698 0.302 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
T43.6 Psychostimulants with abuse potential
0.698 0.302 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.698 0.302 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.698 0.302 0.000
G64 Other disorders of peripheral nervous system
0.698 0.302 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
M24.0 Loose body in joint
0.697 0.303 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.697 0.303 0.000
F09 Unspecified organic or symptomatic mental disorder
0.697 0.303 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.697 0.303 0.000
T19 Foreign body in genito-urinary tract
0.697 0.303 0.000
T15 Foreign body on external eye
0.697 0.303 0.000
T16 Foreign body in ear
0.697 0.303 0.000
T58 Toxic effect of carbon monoxide
0.696 0.304 0.000
J37.0 Chronic laryngitis
0.696 0.304 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.695 0.305 0.000
M06.0 Seronegative rheumatoid arthritis
0.695 0.305 0.000
M46 Other inflammatory spondylopathies
0.694 0.305 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.694 0.306 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.694 0.306 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.693 0.307 0.000
J04 Acute laryngitis and tracheitis
0.693 0.307 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.692 0.308 0.000
G52 Disorders of other cranial nerves
0.692 0.308 0.000
T95 Sequelae of burns, corrosions and frostbite
0.692 0.308 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
S22.0 Fracture of thoracic vertebra
0.692 0.308 0.000
Q28 Other congenital malformations of circulatory system
0.692 0.308 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.691 0.309 0.000
D80-D89 Certain disorders involving the immune mechanism
0.691 0.309 0.000
T13 Other injuries of lower limb, level unspecified
0.690 0.309 0.000
S22.1 Multiple fractures of thoracic spine
0.690 0.310 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.310 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.689 0.310 0.000
G61 Inflammatory polyneuropathy
0.689 0.311 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.689 0.311 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.689 0.311 0.000
J33.8 Other polyp of sinus
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
E04 Other non-toxic goitre
0.688 0.312 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.688 0.312 0.000
G58.7 Mononeuritis multiplex
0.688 0.312 0.000
M54.5 Low back pain
0.688 0.312 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.687 0.313 0.000
S26 Injury of heart
0.687 0.313 0.000
S25 Injury of blood vessels of thorax
0.687 0.313 0.000
S24 Injury of nerves and spinal cord at thorax level
0.687 0.313 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.687 0.313 0.000
M10 Gout
0.686 0.314 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.685 0.315 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.685 0.315 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.685 0.315 0.000
T42.3 Barbiturates
0.685 0.315 0.000
T42.2 Succinimides and oxazolidinediones
0.685 0.315 0.000
T42.1 Iminostilbenes
0.685 0.315 0.000
T42.0 Hydantoin derivatives
0.685 0.315 0.000
M11 Other crystal arthropathies
0.685 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.683 0.316 0.000
T63 Toxic effect of contact with venomous animals
0.683 0.317 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.683 0.317 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.683 0.317 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.683 0.317 0.000
M88 Paget's disease of bone [osteitis deformans]
0.682 0.318 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.680 0.320 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
S91.3 Open wound of other parts of foot
0.678 0.321 0.000
G62.0 Drug-induced polyneuropathy
0.678 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
M20.1 Hallux valgus (acquired)
0.677 0.323 0.000
S27 Injury of other and unspecified intrathoracic organs
0.675 0.325 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.675 0.325 0.000
W44 Foreign body entering into or through eye or natural orifice
0.674 0.326 0.000
M25 Other joint disorders, not elsewhere classified
0.674 0.326 0.000
M24.5 Contracture of joint
0.674 0.326 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.674 0.326 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.672 0.328 0.000
S22.4 Multiple fractures of ribs
0.672 0.328 0.000
F80-F89 Disorders of psychological development
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
M35 Other systemic involvement of connective tissue
0.670 0.330 0.000
W29 Contact with other powered hand tools and household machinery
0.669 0.331 0.000
D72 Other disorders of white blood cells
0.669 0.331 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.668 0.332 0.000
S29 Other and unspecified injuries of thorax
0.668 0.332 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.667 0.333 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.334 0.000
S22.5 Flail chest
0.665 0.335 0.000
T40.4 Other synthetic narcotics
0.665 0.335 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.336 0.000
G62.2 Polyneuropathy due to other toxic agents
0.664 0.336 0.000
G62.1 Alcoholic polyneuropathy
0.664 0.336 0.000
Q24 Other congenital malformations of heart
0.664 0.336 0.000
T68 Hypothermia
0.664 0.336 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.663 0.337 0.000
G30.9 Alzheimer's disease, unspecified
0.663 0.337 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.660 0.339 0.000
G56.2 Lesion of ulnar nerve
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.660 0.340 0.000
Q35-Q37 Cleft lip and cleft palate
0.660 0.340 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.660 0.340 0.000
E83 Disorders of mineral metabolism
0.660 0.340 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.659 0.341 0.000
M65-M68 Disorders of synovium and tendon
0.658 0.342 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.658 0.342 0.000
T45.0 Antiallergic and antiemetic drugs
0.657 0.343 0.000
M87 Osteonecrosis
0.657 0.343 0.000
M24.2 Disorder of ligament
0.657 0.343 0.000
Y86 Sequelae of other accidents
0.656 0.344 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.655 0.345 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.655 0.345 0.000
T18.8 Foreign body in other and multiple parts of alimentary tract
0.653 0.347 0.000
T18.4 Foreign body in colon
0.653 0.347 0.000
T18.3 Foreign body in small intestine
0.653 0.347 0.000
T18.2 Foreign body in stomach
0.653 0.347 0.000
T18.0 Foreign body in mouth
0.653 0.347 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.653 0.347 0.000
J70 Respiratory conditions due to other external agents
0.652 0.348 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.652 0.348 0.000
J66 Airway disease due to specific organic dust
0.652 0.348 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.652 0.348 0.000
J62 Pneumoconiosis due to dust containing silica
0.652 0.348 0.000
J65 Pneumoconiosis associated with tuberculosis
0.652 0.348 0.000
J64 Unspecified pneumoconiosis
0.652 0.348 0.000
J60 Coalworker's pneumoconiosis
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.648 0.351 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.648 0.352 0.000
Q21 Congenital malformations of cardiac septa
0.648 0.352 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.648 0.352 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.648 0.352 0.000
G92 Toxic encephalopathy
0.648 0.352 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.648 0.352 0.000
X41.9 Unspecified place
0.647 0.353 0.000
M22 Disorders of patella
0.647 0.353 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.647 0.353 0.000
M54.3 Sciatica
0.647 0.353 0.000
V48 Car occupant injured in noncollision transport accident
0.647 0.353 0.000
G91.2 Normal-pressure hydrocephalus
0.646 0.354 0.000
E74 Other disorders of carbohydrate metabolism
0.644 0.356 0.000
M90 Osteopathies in diseases classified elsewhere
0.644 0.356 0.000
S90 Superficial injury of ankle and foot
0.643 0.357 0.000
M06.34 Rheumatoid nodule (Hand)
0.643 0.357 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.643 0.357 0.000
S98 Traumatic amputation of ankle and foot
0.642 0.358 0.000
S97 Crushing injury of ankle and foot
0.642 0.358 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.642 0.358 0.000
S95 Injury of blood vessels at ankle and foot level
0.642 0.358 0.000
S94 Injury of nerves at ankle and foot level
0.642 0.358 0.000
G51.9 Disorder of facial nerve, unspecified
0.642 0.358 0.000
J39.9 Disease of upper respiratory tract, unspecified
0.642 0.358 0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.642 0.358 0.000
J39.1 Other abscess of pharynx
0.642 0.358 0.000
J39.0 Retropharyngeal and parapharyngeal abscess
0.642 0.358 0.000
M86 Osteomyelitis
0.640 0.359 0.000
F60-F69 Disorders of adult personality and behaviour
0.640 0.359 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.640 0.360 0.000
T40.8 Lysergide [LSD]
0.640 0.360 0.000
T40.7 Cannabis (derivatives)
0.640 0.360 0.000
T40.6 Other and unspecified narcotics
0.640 0.360 0.000
T40.5 Cocaine
0.640 0.360 0.000
T40.3 Methadone
0.640 0.360 0.000
T40.1 Heroin
0.640 0.360 0.000
T40.0 Opium
0.640 0.360 0.000
Q00-Q07 Congenital malformations of the nervous system
0.640 0.360 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.638 0.362 0.000
G83 Other paralytic syndromes
0.637 0.363 0.000
E87.0 Hyperosmolality and hypernatraemia
0.637 0.363 0.000
E84 Cystic fibrosis
0.636 0.364 0.000
E79 Disorders of purine and pyrimidine metabolism
0.636 0.364 0.000
E77 Disorders of glycoprotein metabolism
0.636 0.364 0.000
E76 Disorders of glycosaminoglycan metabolism
0.636 0.364 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.636 0.364 0.000
E72 Other disorders of amino-acid metabolism
0.636 0.364 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.636 0.364 0.000
E70 Disorders of aromatic amino-acid metabolism
0.636 0.364 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.636 0.364 0.000
M91-M94 Chondropathies
0.636 0.364 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.635 0.365 0.000
S91.1 Open wound of toe(s) without damage to nail
0.635 0.365 0.000
S64.4 Injury of digital nerve of other finger
0.635 0.365 0.000
M25.8 Other specified joint disorders
0.634 0.366 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.633 0.367 0.000
E87.4 Mixed disorder of acid-base balance
0.633 0.367 0.000
Y40.9 Systemic antibiotic, unspecified
0.633 0.367 0.000
T90.9 Sequelae of unspecified injury of head
0.633 0.367 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.633 0.367 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.632 0.368 0.000
M24.9 Joint derangement, unspecified
0.632 0.368 0.000
M24.7 Protrusio acetabuli
0.632 0.368 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.632 0.368 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.632 0.368 0.000
T17.5 Foreign body in bronchus
0.632 0.368 0.000
T17.4 Foreign body in trachea
0.632 0.368 0.000
T17.3 Foreign body in larynx
0.632 0.368 0.000
T17.1 Foreign body in nostril
0.632 0.368 0.000
T17.0 Foreign body in nasal sinus
0.632 0.368 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.632 0.368 0.000
J01.9 Acute sinusitis, unspecified
0.632 0.368 0.000
M51.3 Other specified intervertebral disk degeneration
0.631 0.368 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.631 0.368 0.000
M51.4 Schmorl's nodes
0.631 0.368 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.631 0.369 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.631 0.369 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.631 0.369 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.630 0.370 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.630 0.370 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.630 0.370 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.630 0.370 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.630 0.370 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.630 0.370 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.630 0.370 0.000
T44.0 Anticholinesterase agents
0.630 0.370 0.000
X48 Accidental poisoning by and exposure to pesticides
0.629 0.370 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.629 0.370 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.629 0.370 0.000
X45 Accidental poisoning by and exposure to alcohol
0.629 0.370 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.629 0.370 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.629 0.370 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.629 0.370 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.629 0.370 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.629 0.371 0.000
G58.0 Intercostal neuropathy
0.629 0.371 0.000
Q26 Congenital malformations of great veins
0.628 0.372 0.000
Q25 Congenital malformations of great arteries
0.628 0.372 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.628 0.372 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.628 0.372 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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