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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4635580
log Bayes Factor = 7.44251
Chromosome 20   position 40,949,831  (GRCh37) Explore rs4635580 on Ensembl!
Variant rs4635580 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
K70 Alcoholic liver disease
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
I51 Complications and ill-defined descriptions of heart disease
0.980 0.020 0.000
H65-H75 Diseases of middle ear and mastoid
0.978 0.022 0.000
E10-E14 Diabetes mellitus
0.975 0.025 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.974 0.026 0.000
K70.4 Alcoholic hepatic failure
0.974 0.026 0.000
I51.7 Cardiomegaly
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.972 0.028 0.000
E10 Insulin-dependent diabetes mellitus
0.970 0.030 0.000
E00-E07 Disorders of thyroid gland
0.970 0.030 0.000
O00-O08 Pregnancy with abortive outcome
0.969 0.031 0.000
K40-K46 Hernia
0.962 0.038 0.000
K42 Umbilical hernia
0.960 0.040 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.959 0.041 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.959 0.041 0.000
O03 Spontaneous abortion
0.958 0.042 0.000
K70.9 Alcoholic liver disease, unspecified
0.953 0.047 0.000
E03 Other hypothyroidism
0.952 0.048 0.000
K70.3 Alcoholic cirrhosis of liver
0.950 0.050 0.000
K65-K67 Diseases of peritoneum
0.950 0.050 0.000
O03.9 Complete or unspecified, without complication
0.948 0.052 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.942 0.058 0.000
E03.9 Hypothyroidism, unspecified
0.940 0.060 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.938 0.062 0.000
H80-H83 Diseases of inner ear
0.928 0.072 0.000
E10.3 With ophthalmic complications
0.924 0.076 0.000
I47 Paroxysmal tachycardia
0.923 0.077 0.000
S40-S49 Injuries to the shoulder and upper arm
0.920 0.080 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.918 0.082 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.917 0.083 0.000
E65-E68 Obesity and other hyperalimentation
0.917 0.083 0.000
H90-H95 Other disorders of ear
0.916 0.084 0.000
M20-M25 Other joint disorders
0.913 0.087 0.000
M70-M79 Other soft tissue disorders
0.911 0.089 0.000
E10.1 With ketoacidosis
0.910 0.090 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.908 0.092 0.000
I85 Oesophageal varices
0.901 0.099 0.000
H72 Perforation of tympanic membrane
0.900 0.100 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.898 0.102 0.000
O02 Other abnormal products of conception
0.892 0.108 0.000
K66 Other disorders of peritoneum
0.892 0.108 0.000
Chapter X Diseases of the respiratory system
0.889 0.111 0.000
I85.9 Oesophageal varices without bleeding
0.888 0.112 0.000
I37 Pulmonary valve disorders
0.884 0.116 0.000
H74 Other disorders of middle ear and mastoid
0.884 0.116 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.880 0.120 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.880 0.120 0.000
I71 Aortic aneurysm and dissection
0.880 0.120 0.000
I47.2 Ventricular tachycardia
0.877 0.123 0.000
M40-M43 Deforming dorsopathies
0.876 0.124 0.000
H66 Suppurative and unspecified otitis media
0.875 0.125 0.000
H93 Other disorders of ear, not elsewhere classified
0.867 0.133 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.867 0.133 0.000
I05-I09 Chronic rheumatic heart diseases
0.863 0.137 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
E66 Obesity
0.859 0.141 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.856 0.144 0.000
E04 Other non-toxic goitre
0.853 0.147 0.000
K70.0 Alcoholic fatty liver
0.852 0.148 0.000
S10-S19 Injuries to the neck
0.852 0.148 0.000
H60-H62 Diseases of external ear
0.851 0.149 0.000
K66.0 Peritoneal adhesions
0.849 0.151 0.000
J90-J94 Other diseases of pleura
0.848 0.152 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.844 0.156 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.843 0.157 0.000
K11 Diseases of salivary glands
0.843 0.157 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.840 0.160 0.000
E66.9 Obesity, unspecified
0.837 0.163 0.000
M70.6 Trochanteric bursitis
0.837 0.163 0.000
K02 Dental caries
0.832 0.168 0.000
Chapter I Certain infectious and parasitic diseases
0.826 0.174 0.000
K76 Other diseases of liver
0.822 0.178 0.000
M21 Other acquired deformities of limbs
0.821 0.179 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.818 0.182 0.000
E20-E35 Disorders of other endocrine glands
0.815 0.185 0.000
I37.1 Pulmonary valve insufficiency
0.811 0.189 0.000
I72 Other aneurysm
0.810 0.190 0.000
K46 Unspecified abdominal hernia
0.809 0.191 0.000
E10.4 With neurological complications
0.808 0.192 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.806 0.194 0.000
O02.1 Missed abortion
0.806 0.194 0.000
M65-M68 Disorders of synovium and tendon
0.804 0.196 0.000
O85-O92 Complications predominantly related to the puerperium
0.801 0.199 0.000
J92 Pleural plaque
0.800 0.200 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.800 0.200 0.000
I78 Diseases of capillaries
0.800 0.200 0.000
M22 Disorders of patella
0.797 0.203 0.000
I77 Other disorders of arteries and arterioles
0.797 0.203 0.000
H80 Otosclerosis
0.797 0.203 0.000
H93.1 Tinnitus
0.794 0.206 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.791 0.209 0.000
H74.0 Tympanosclerosis
0.789 0.211 0.000
I51.8 Other ill-defined heart diseases
0.789 0.211 0.000
K65 Peritonitis
0.788 0.212 0.000
S20-S29 Injuries to the thorax
0.787 0.213 0.000
I45 Other conduction disorders
0.783 0.217 0.000
E04.9 Non-toxic goitre, unspecified
0.783 0.217 0.000
J09-J18 Influenza and pneumonia
0.782 0.218 0.000
H83 Other diseases of inner ear
0.781 0.219 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.780 0.220 0.000
I86 Varicose veins of other sites
0.780 0.220 0.000
K11.5 Sialolithiasis
0.779 0.221 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.779 0.221 0.000
I46 Cardiac arrest
0.778 0.222 0.000
E10.9 Without complications
0.778 0.222 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.775 0.225 0.000
M43 Other deforming dorsopathies
0.774 0.226 0.000
S70-S79 Injuries to the hip and thigh
0.773 0.226 0.000
K76.9 Liver disease, unspecified
0.772 0.228 0.000
I35 Nonrheumatic aortic valve disorders
0.769 0.231 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
O03.4 Incomplete, without complication
0.765 0.235 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.765 0.235 0.000
K70.1 Alcoholic hepatitis
0.764 0.236 0.000
E10.5 With peripheral circulatory complications
0.764 0.236 0.000
S60-S69 Injuries to the wrist and hand
0.761 0.239 0.000
I95 Hypotension
0.761 0.239 0.000
J00-J06 Acute upper respiratory infections
0.760 0.240 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.756 0.244 0.000
M70.4 Prepatellar bursitis
0.755 0.245 0.000
K74 Fibrosis and cirrhosis of liver
0.755 0.245 0.000
I71.0 Dissection of aorta [any part]
0.754 0.246 0.000
H66.3 Other chronic suppurative otitis media
0.753 0.247 0.000
I70 Atherosclerosis
0.752 0.248 0.000
S42 Fracture of shoulder and upper arm
0.751 0.249 0.000
H72.8 Other perforations of tympanic membrane
0.750 0.250 0.000
H93.9 Disorder of ear, unspecified
0.750 0.250 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.750 0.250 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.750 0.250 0.000
M34 Systemic sclerosis
0.750 0.250 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.749 0.251 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.749 0.251 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.747 0.253 0.000
I51.0 Cardiac septal defect, acquired
0.747 0.253 0.000
H81 Disorders of vestibular function
0.745 0.255 0.000
H90 Conductive and sensorineural hearing loss
0.745 0.255 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.743 0.257 0.000
H69 Other disorders of Eustachian tube
0.742 0.258 0.000
T92 Sequelae of injuries of upper limb
0.741 0.259 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.741 0.259 0.000
M23 Internal derangement of knee
0.740 0.260 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.740 0.260 0.000
O80-O84 Delivery
0.739 0.261 0.000
T00-T07 Injuries involving multiple body regions
0.737 0.263 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.737 0.263 0.000
H60 Otitis externa
0.736 0.264 0.000
H71 Cholesteatoma of middle ear
0.736 0.264 0.000
I38 Endocarditis, valve unspecified
0.734 0.266 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.733 0.267 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.732 0.268 0.000
T90 Sequelae of injuries of head
0.732 0.268 0.000
M41 Scoliosis
0.731 0.268 0.000
K13 Other diseases of lip and oral mucosa
0.731 0.269 0.000
M22.4 Chondromalacia patellae
0.729 0.271 0.000
I30 Acute pericarditis
0.729 0.271 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.728 0.272 0.000
J92.9 Pleural plaque without asbestos
0.728 0.272 0.000
Q80-Q89 Other congenital malformations
0.727 0.273 0.000
I74 Arterial embolism and thrombosis
0.726 0.274 0.000
S10 Superficial injury of neck
0.725 0.274 0.000
M30 Polyarteritis nodosa and related conditions
0.725 0.275 0.000
B35-B49 Mycoses
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.724 0.276 0.000
I08 Multiple valve diseases
0.724 0.276 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.721 0.279 0.000
I87 Other disorders of veins
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.719 0.281 0.000
H70 Mastoiditis and related conditions
0.718 0.282 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
K45 Other abdominal hernia
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
K73 Chronic hepatitis, not elsewhere classified
0.716 0.284 0.000
K71 Toxic liver disease
0.716 0.284 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.716 0.284 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.715 0.285 0.000
K02.9 Dental caries, unspecified
0.715 0.285 0.000
K02.1 Caries of dentin
0.712 0.288 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.709 0.291 0.000
K72 Hepatic failure, not elsewhere classified
0.708 0.292 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.708 0.292 0.000
K12 Stomatitis and related lesions
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.292 0.000
I48 Atrial fibrillation and flutter
0.707 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.292 0.000
I40 Acute myocarditis
0.707 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.292 0.000
I05 Rheumatic mitral valve diseases
0.707 0.292 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.707 0.293 0.000
M77 Other enthesopathies
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
J94 Other pleural conditions
0.706 0.294 0.000
K10 Other diseases of jaws
0.706 0.294 0.000
O04 Medical abortion
0.705 0.295 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.703 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.296 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
I51.5 Myocardial degeneration
0.703 0.297 0.000
I51.4 Myocarditis, unspecified
0.703 0.297 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.703 0.297 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.703 0.297 0.000
I81 Portal vein thrombosis
0.703 0.297 0.000
H80.9 Otosclerosis, unspecified
0.703 0.297 0.000
M23.3 Other meniscus derangements
0.702 0.298 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.701 0.299 0.000
H68 Eustachian salpingitis and obstruction
0.701 0.299 0.000
H67 Otitis media in diseases classified elsewhere
0.701 0.299 0.000
M71 Other bursopathies
0.700 0.300 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.699 0.301 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.698 0.302 0.000
M72 Fibroblastic disorders
0.698 0.302 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.697 0.303 0.000
I99 Other and unspecified disorders of circulatory system
0.696 0.304 0.000
E10.8 With unspecified complications
0.696 0.304 0.000
E10.7 With multiple complications
0.696 0.304 0.000
E10.6 With other specified complications
0.696 0.304 0.000
E10.0 With coma
0.696 0.304 0.000
M21.1 Varus deformity, not elsewhere classified
0.695 0.304 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.695 0.305 0.000
E00 Congenital iodine-deficiency syndrome
0.695 0.305 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.695 0.305 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.695 0.305 0.000
O07 Failed attempted abortion
0.695 0.305 0.000
O06 Unspecified abortion
0.695 0.305 0.000
O05 Other abortion
0.695 0.305 0.000
O01 Hydatidiform mole
0.695 0.305 0.000
Q00-Q07 Congenital malformations of the nervous system
0.695 0.305 0.000
E50-E64 Other nutritional deficiencies
0.694 0.305 0.000
M86-M90 Other osteopathies
0.693 0.307 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.692 0.307 0.000
J92.0 Pleural plaque with presence of asbestos
0.691 0.309 0.000
I47.0 Reentry ventricular arrhythmia
0.690 0.310 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.690 0.310 0.000
T98 Sequelae of other and unspecified effects of external causes
0.689 0.311 0.000
K42.1 Umbilical hernia with gangrene
0.688 0.312 0.000
E13 Other specified diabetes mellitus
0.687 0.312 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.687 0.313 0.000
O03.7 Complete or unspecified, complicated by embolism
0.687 0.313 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.687 0.313 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.687 0.313 0.000
O03.3 Incomplete, with other and unspecified complications
0.687 0.313 0.000
O03.2 Incomplete, complicated by embolism
0.687 0.313 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.687 0.313 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.687 0.313 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.687 0.313 0.000
E10.2 With renal complications
0.685 0.315 0.000
M24 Other specific joint derangements
0.685 0.315 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.685 0.315 0.000
T91 Sequelae of injuries of neck and trunk
0.683 0.317 0.000
E03.8 Other specified hypothyroidism
0.683 0.317 0.000
E03.5 Myxoedema coma
0.683 0.317 0.000
E03.4 Atrophy of thyroid (acquired)
0.683 0.317 0.000
E03.3 Postinfectious hypothyroidism
0.683 0.317 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.683 0.317 0.000
E03.1 Congenital hypothyroidism without goitre
0.683 0.317 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.683 0.317 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.683 0.317 0.000
J02 Acute pharyngitis
0.682 0.318 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.682 0.318 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.681 0.319 0.000
K04 Diseases of pulp and periapical tissues
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.679 0.321 0.000
Chapter XX External causes of morbidity and mortality
0.679 0.321 0.000
H72.0 Central perforation of tympanic membrane
0.678 0.322 0.000
I36 Nonrheumatic tricuspid valve disorders
0.678 0.322 0.000
J93 Pneumothorax
0.677 0.323 0.000
M43.1 Spondylolisthesis
0.677 0.323 0.000
H83.0 Labyrinthitis
0.676 0.324 0.000
K66.1 Haemoperitoneum
0.676 0.324 0.000
K74.6 Other and unspecified cirrhosis of liver
0.675 0.324 0.000
S20 Superficial injury of thorax
0.675 0.325 0.000
K65.9 Peritonitis, unspecified
0.673 0.327 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.671 0.329 0.000
I85.0 Oesophageal varices with bleeding
0.671 0.329 0.000
J84 Other interstitial pulmonary diseases
0.671 0.329 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.670 0.330 0.000
S50-S59 Injuries to the elbow and forearm
0.670 0.330 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.669 0.331 0.000
I95.9 Hypotension, unspecified
0.668 0.332 0.000
K11.7 Disturbances of salivary secretion
0.668 0.332 0.000
I86.1 Scrotal varices
0.667 0.333 0.000
Chapter XXII Codes for special purposes
0.666 0.334 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.666 0.334 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.665 0.335 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.335 0.000
I35.1 Aortic (valve) insufficiency
0.665 0.335 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.664 0.335 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.664 0.336 0.000
I45.3 Trifascicular block
0.664 0.336 0.000
I72.4 Aneurysm of artery of lower extremity
0.663 0.337 0.000
M00-M03 Infectious arthropathies
0.663 0.337 0.000
J91 Pleural effusion in conditions classified elsewhere
0.663 0.337 0.000
M91-M94 Chondropathies
0.663 0.337 0.000
S48 Traumatic amputation of shoulder and upper arm
0.660 0.340 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.660 0.340 0.000
S44 Injury of nerves at shoulder and upper arm level
0.660 0.340 0.000
S41 Open wound of shoulder and upper arm
0.660 0.340 0.000
S47 Crushing injury of shoulder and upper arm
0.660 0.340 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.660 0.340 0.000
H66.9 Otitis media, unspecified
0.659 0.341 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.658 0.341 0.000
I88 Nonspecific lymphadenitis
0.657 0.343 0.000
E67 Other hyperalimentation
0.657 0.343 0.000
E68 Sequelae of hyperalimentation
0.657 0.343 0.000
E65 Localised adiposity
0.657 0.343 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.656 0.343 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.656 0.343 0.000
K11.9 Disease of salivary gland, unspecified
0.656 0.344 0.000
T86 Failure and rejection of transplanted organs and tissues
0.656 0.344 0.000
I46.9 Cardiac arrest, unspecified
0.655 0.344 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.655 0.345 0.000
M33 Dermatopolymyositis
0.655 0.345 0.000
K09 Cysts of oral region, not elsewhere classified
0.654 0.346 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.653 0.346 0.000
S12 Fracture of neck
0.652 0.348 0.000
K13.0 Diseases of lips
0.652 0.348 0.000
K03 Other diseases of hard tissues of teeth
0.651 0.349 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.651 0.349 0.000
O90 Complications of the puerperium, not elsewhere classified
0.650 0.350 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.650 0.350 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.650 0.350 0.000
K05 Gingivitis and periodontal diseases
0.649 0.351 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.649 0.351 0.000
S42.3 Fracture of shaft of humerus
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.647 0.353 0.000
H72.2 Other marginal perforations of tympanic membrane
0.645 0.355 0.000
H72.1 Attic perforation of tympanic membrane
0.645 0.355 0.000
K12.2 Cellulitis and abscess of mouth
0.645 0.355 0.000
I72.0 Aneurysm of carotid artery
0.644 0.356 0.000
T95 Sequelae of burns, corrosions and frostbite
0.643 0.356 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.643 0.356 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.643 0.356 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.643 0.356 0.000
J60-J70 Lung diseases due to external agents
0.643 0.357 0.000
M76 Enthesopathies of lower limb, excluding foot
0.643 0.357 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.643 0.357 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
M66 Spontaneous rupture of synovium and tendon
0.642 0.358 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.642 0.358 0.000
M79.1 Myalgia
0.642 0.358 0.000
O02.9 Abnormal product of conception, unspecified
0.640 0.360 0.000
O02.8 Other specified abnormal products of conception
0.640 0.360 0.000
K66.9 Disorder of peritoneum, unspecified
0.639 0.361 0.000
E04.0 Non-toxic diffuse goitre
0.638 0.362 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.638 0.362 0.000
T93 Sequelae of injuries of lower limb
0.637 0.363 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.363 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.636 0.364 0.000
E06 Thyroiditis
0.636 0.364 0.000
M21.0 Valgus deformity, not elsewhere classified
0.636 0.364 0.000
T42.4 Benzodiazepines
0.635 0.365 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.635 0.365 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.635 0.365 0.000
S10.9 Superficial injury of neck, part unspecified
0.635 0.365 0.000
I37.9 Pulmonary valve disorder, unspecified
0.634 0.366 0.000
I37.8 Other pulmonary valve disorders
0.634 0.366 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.634 0.366 0.000
I37.0 Pulmonary valve stenosis
0.634 0.366 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.634 0.366 0.000
H74.4 Polyp of middle ear
0.634 0.366 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.634 0.366 0.000
H74.1 Adhesive middle ear disease
0.634 0.366 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.634 0.366 0.000
A15-A19 Tuberculosis
0.633 0.367 0.000
M85 Other disorders of bone density and structure
0.633 0.367 0.000
B02 Zoster [herpes zoster]
0.632 0.368 0.000
I50 Heart failure
0.632 0.368 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.632 0.368 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.631 0.369 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.631 0.369 0.000
M70.7 Other bursitis of hip
0.631 0.369 0.000
M70.5 Other bursitis of knee
0.631 0.369 0.000
M70.3 Other bursitis of elbow
0.631 0.369 0.000
M70.1 Bursitis of hand
0.631 0.369 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.631 0.369 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.631 0.369 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.631 0.369 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.631 0.369 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.631 0.369 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.631 0.369 0.000
T82.1 Mechanical complication of cardiac electronic device
0.630 0.370 0.000
O21 Excessive vomiting in pregnancy
0.630 0.370 0.000
O16 Unspecified maternal hypertension
0.630 0.370 0.000
I82 Other venous embolism and thrombosis
0.630 0.370 0.000
E23 Hypofunction and other disorders of pituitary gland
0.630 0.370 0.000
E40-E46 Malnutrition
0.629 0.370 0.000
M22.2 Patellofemoral disorders
0.629 0.371 0.000
H61 Other disorders of external ear
0.628 0.372 0.000
M42 Spinal osteochondrosis
0.628 0.372 0.000
M40 Kyphosis and lordosis
0.628 0.372 0.000
I77.6 Arteritis, unspecified
0.628 0.372 0.000
M41.9 Scoliosis, unspecified
0.628 0.372 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.628 0.372 0.000
B99-B99 Other infectious diseases
0.628 0.372 0.000
H66.4 Suppurative otitis media, unspecified
0.627 0.373 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.627 0.373 0.000
H66.0 Acute suppurative otitis media
0.627 0.373 0.000
J02.9 Acute pharyngitis, unspecified
0.626 0.374 0.000
M21.2 Flexion deformity
0.626 0.374 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.625 0.375 0.000
M21.3 Wrist or foot drop (acquired)
0.625 0.375 0.000
I33 Acute and subacute endocarditis
0.625 0.375 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.625 0.375 0.000
S40 Superficial injury of shoulder and upper arm
0.624 0.376 0.000
O82 Single delivery by Caesarean section
0.624 0.376 0.000
O87 Venous complications in the puerperium
0.624 0.376 0.000
K76.7 Hepatorenal syndrome
0.623 0.376 0.000
S42.1 Fracture of scapula
0.622 0.378 0.000
H60.9 Otitis externa, unspecified
0.622 0.378 0.000
K08 Other disorders of teeth and supporting structures
0.622 0.378 0.000
M67 Other disorders of synovium and tendon
0.622 0.378 0.000
H93.8 Other specified disorders of ear
0.622 0.378 0.000
H93.3 Disorders of acoustic nerve
0.622 0.378 0.000
H93.2 Other abnormal auditory perceptions
0.622 0.378 0.000
H93.0 Degenerative and vascular disorders of ear
0.622 0.378 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.621 0.379 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.621 0.379 0.000
I98.0 Cardiovascular syphilis
0.621 0.379 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.621 0.379 0.000
M70.2 Olecranon bursitis
0.620 0.380 0.000
M79.7 Fibromyalgia
0.620 0.380 0.000
B07 Viral warts
0.620 0.380 0.000
I09 Other rheumatic heart diseases
0.619 0.381 0.000
I06 Rheumatic aortic valve diseases
0.619 0.381 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.619 0.381 0.000
Q35-Q37 Cleft lip and cleft palate
0.619 0.381 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.619 0.381 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.619 0.381 0.000
I47.1 Supraventricular tachycardia
0.618 0.382 0.000
K02.8 Other dental caries
0.617 0.383 0.000
J11 Influenza, virus not identified
0.617 0.383 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.617 0.383 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.616 0.383 0.000
H90.3 Sensorineural hearing loss, bilateral
0.616 0.384 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.616 0.384 0.000
E66.1 Drug-induced obesity
0.616 0.384 0.000
E66.0 Obesity due to excess calories
0.616 0.384 0.000
B44 Aspergillosis
0.616 0.384 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.615 0.384 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.614 0.386 0.000
S37 Injury of urinary and pelvic organs
0.614 0.386 0.000
S36 Injury of intra-abdominal organs
0.614 0.386 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.614 0.386 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.614 0.386 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.614 0.386 0.000
S31 Open wound of abdomen, lower back and pelvis
0.614 0.386 0.000
I70.0 Atherosclerosis of aorta
0.614 0.386 0.000
Q50-Q56 Congenital malformations of genital organs
0.613 0.386 0.000
B18 Chronic viral hepatitis
0.613 0.387 0.000
I77.0 Arteriovenous fistula, acquired
0.613 0.387 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.612 0.387 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.612 0.388 0.000
E04.8 Other specified non-toxic goitre
0.612 0.388 0.000
S17 Crushing injury of neck
0.611 0.389 0.000
S15 Injury of blood vessels at neck level
0.611 0.389 0.000
S14 Injury of nerves and spinal cord at neck level
0.611 0.389 0.000
S11 Open wound of neck
0.611 0.389 0.000
S18 Traumatic amputation at neck level
0.611 0.389 0.000
S16 Injury of muscle and tendon at neck level
0.611 0.389 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.610 0.390 0.000
M43.0 Spondylolysis
0.610 0.390 0.000
K00 Disorders of tooth development and eruption
0.609 0.390 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.609 0.391 0.000
M65 Synovitis and tenosynovitis
0.609 0.391 0.000
I45.1 Other and unspecified right bundle-branch block
0.608 0.392 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.608 0.392 0.000
M35 Other systemic involvement of connective tissue
0.608 0.392 0.000
I44 Atrioventricular and left bundle-branch block
0.606 0.394 0.000
E28 Ovarian dysfunction
0.606 0.394 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.606 0.394 0.000
E04.2 Non-toxic multinodular goitre
0.606 0.394 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.605 0.395 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.605 0.395 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.605 0.395 0.000
E07 Other disorders of thyroid
0.605 0.395 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.605 0.395 0.000
E14 Unspecified diabetes mellitus
0.605 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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