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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4715057
log Bayes Factor = 0.354989
Chromosome 6   position 47,953,801  (GRCh37) Explore rs4715057 on Ensembl!
Variant rs4715057 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.000 0.484 0.516
I50 Heart failure
0.000 0.486 0.514
I25 Chronic ischaemic heart disease
0.000 0.487 0.513
I20-I25 Ischaemic heart diseases
0.000 0.489 0.511
I20.9 Angina pectoris, unspecified
0.000 0.497 0.503
I20 Angina pectoris
0.000 0.497 0.502
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.505 0.495
I34 Nonrheumatic mitral valve disorders
0.000 0.507 0.493
I50.0 Congestive heart failure
0.000 0.508 0.492
Chapter IX Diseases of the circulatory system
0.000 0.518 0.482
I50.1 Left ventricular failure
0.000 0.526 0.474
I25.1 Atherosclerotic heart disease
0.000 0.533 0.467
I34.0 Mitral (valve) insufficiency
0.000 0.535 0.465
I47 Paroxysmal tachycardia
0.000 0.544 0.456
I25.2 Old myocardial infarction
0.000 0.557 0.443
I35 Nonrheumatic aortic valve disorders
0.000 0.566 0.434
I50.9 Heart failure, unspecified
0.000 0.573 0.427
I44 Atrioventricular and left bundle-branch block
0.000 0.578 0.422
I38 Endocarditis, valve unspecified
0.000 0.583 0.417
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.583 0.417
I47.2 Ventricular tachycardia
0.000 0.591 0.409
I34.1 Mitral (valve) prolapse
0.000 0.594 0.406
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.619 0.381
I44.7 Left bundle-branch block, unspecified
0.000 0.623 0.377
I46 Cardiac arrest
0.000 0.625 0.375
I52 Other heart disorders in diseases classified elsewhere
0.000 0.630 0.370
I48 Atrial fibrillation and flutter
0.000 0.630 0.370
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.630 0.370
I41 Myocarditis in diseases classified elsewhere
0.000 0.630 0.370
I40 Acute myocarditis
0.000 0.630 0.370
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.630 0.370
I37 Pulmonary valve disorders
0.000 0.630 0.370
I36 Nonrheumatic tricuspid valve disorders
0.000 0.630 0.370
I33 Acute and subacute endocarditis
0.000 0.630 0.370
I32 Pericarditis in diseases classified elsewhere
0.000 0.630 0.370
I30 Acute pericarditis
0.000 0.630 0.370
I25.6 Silent myocardial ischaemia
0.000 0.632 0.368
I25.5 Ischaemic cardiomyopathy
0.000 0.632 0.368
I25.4 Coronary artery aneurysm
0.000 0.632 0.368
I25.3 Aneurysm of heart
0.000 0.632 0.368
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.632 0.368
I47.1 Supraventricular tachycardia
0.000 0.633 0.366
I23 Certain current complications following acute myocardial infarction
0.000 0.634 0.366
I35.0 Aortic (valve) stenosis
0.000 0.636 0.364
I45 Other conduction disorders
0.000 0.638 0.362
I24 Other acute ischaemic heart diseases
0.000 0.640 0.360
I42 Cardiomyopathy
0.000 0.643 0.357
I51 Complications and ill-defined descriptions of heart disease
0.000 0.643 0.357
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.647 0.353
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.647 0.353
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.647 0.353
I00-I02 Acute rheumatic fever
0.000 0.654 0.346
I20.0 Unstable angina
0.000 0.654 0.346
I22 Subsequent myocardial infarction
0.000 0.658 0.342
I20.1 Angina pectoris with documented spasm
0.000 0.662 0.337
I47.0 Reentry ventricular arrhythmia
0.000 0.673 0.327
I44.0 Atrioventricular block, first degree
0.000 0.673 0.327
I05-I09 Chronic rheumatic heart diseases
0.000 0.673 0.326
I35.1 Aortic (valve) insufficiency
0.000 0.675 0.325
I95 Hypotension
0.000 0.681 0.319
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.681 0.318
I35.9 Aortic valve disorder, unspecified
0.000 0.689 0.311
I35.8 Other aortic valve disorders
0.000 0.689 0.311
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.689 0.311
I51.7 Cardiomegaly
0.000 0.690 0.310
I44.1 Atrioventricular block, second degree
0.000 0.697 0.303
I44.6 Other and unspecified fascicular block
0.000 0.697 0.302
I44.5 Left posterior fascicular block
0.000 0.697 0.302
I44.4 Left anterior fascicular block
0.000 0.697 0.302
I44.3 Other and unspecified atrioventricular block
0.000 0.697 0.302
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.698 0.302
I45.1 Other and unspecified right bundle-branch block
0.000 0.706 0.294
I21 Acute myocardial infarction
0.000 0.709 0.291
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.713 0.287
I31 Other diseases of pericardium
0.000 0.714 0.286
I46.0 Cardiac arrest with successful resuscitation
0.000 0.715 0.285
I95.9 Hypotension, unspecified
0.000 0.716 0.284
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.720 0.280
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.726 0.273
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.730 0.269
I46.1 Sudden cardiac death, so described
0.000 0.731 0.269
I20.8 Other forms of angina pectoris
0.000 0.731 0.268
I49 Other cardiac arrhythmias
0.000 0.734 0.266
I30.9 Acute pericarditis, unspecified
0.000 0.734 0.265
I30.8 Other forms of acute pericarditis
0.000 0.734 0.265
I30.1 Infective pericarditis
0.000 0.734 0.265
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.734 0.265
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.734 0.265
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.265
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.734 0.265
I33.9 Acute endocarditis, unspecified
0.000 0.734 0.265
I33.0 Acute and subacute infective endocarditis
0.000 0.734 0.265
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.734 0.265
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.734 0.265
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.734 0.265
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.734 0.265
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.734 0.265
I37.9 Pulmonary valve disorder, unspecified
0.000 0.734 0.265
I37.8 Other pulmonary valve disorders
0.000 0.734 0.265
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.734 0.265
I37.1 Pulmonary valve insufficiency
0.000 0.734 0.265
I37.0 Pulmonary valve stenosis
0.000 0.734 0.265
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.734 0.265
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.734 0.265
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.734 0.265
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.734 0.265
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.734 0.265
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.734 0.265
I40.9 Acute myocarditis, unspecified
0.000 0.734 0.265
I40.8 Other acute myocarditis
0.000 0.734 0.265
I40.1 Isolated myocarditis
0.000 0.734 0.265
I40.0 Infective myocarditis
0.000 0.734 0.265
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.734 0.265
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.265
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.734 0.265
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.734 0.265
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.734 0.265
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.734 0.265
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.734 0.265
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.734 0.265
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.734 0.265
I48.4 Atypical atrial flutter
0.000 0.734 0.265
I48.3 Typical atrial flutter
0.000 0.734 0.265
I48.2 Chronic atrial fibrillation
0.000 0.734 0.265
I48.1 Persistent atrial fibrillation
0.000 0.734 0.265
I48.0 Paroxysmal atrial fibrillation
0.000 0.734 0.265
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.734 0.265
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.265
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.734 0.265
I23.8 Other current complications following acute myocardial infarction
0.000 0.737 0.263
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.737 0.263
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.737 0.263
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.737 0.263
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.737 0.263
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.737 0.263
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.737 0.263
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.737 0.263
I42.0 Dilated cardiomyopathy
0.000 0.739 0.261
I45.9 Conduction disorder, unspecified
0.000 0.740 0.259
I45.8 Other specified conduction disorders
0.000 0.740 0.259
I45.5 Other specified heart block
0.000 0.740 0.259
I45.4 Nonspecific intraventricular block
0.000 0.740 0.259
I45.3 Trifascicular block
0.000 0.740 0.259
I45.2 Bifascicular block
0.000 0.740 0.259
I45.0 Right fascicular block
0.000 0.740 0.259
I24.1 Dressler's syndrome
0.000 0.742 0.258
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.742 0.258
I42.8 Other cardiomyopathies
0.000 0.744 0.256
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.744 0.256
I42.6 Alcoholic cardiomyopathy
0.000 0.744 0.256
I42.5 Other restrictive cardiomyopathy
0.000 0.744 0.256
I42.4 Endocardial fibroelastosis
0.000 0.744 0.256
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.744 0.256
I42.2 Other hypertrophic cardiomyopathy
0.000 0.744 0.256
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.744 0.256
I51.6 Cardiovascular disease, unspecified
0.000 0.744 0.256
I51.5 Myocardial degeneration
0.000 0.744 0.256
I51.4 Myocarditis, unspecified
0.000 0.744 0.256
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.744 0.256
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.744 0.256
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.744 0.256
I51.0 Cardiac septal defect, acquired
0.000 0.744 0.256
I46.9 Cardiac arrest, unspecified
0.000 0.745 0.255
I10-I15 Hypertensive diseases
0.000 0.750 0.250
I99 Other and unspecified disorders of circulatory system
0.000 0.751 0.249
I02 Rheumatic chorea
0.000 0.752 0.248
I01 Rheumatic fever with heart involvement
0.000 0.752 0.248
I00 Rheumatic fever without mention of heart involvement
0.000 0.752 0.248
I22.8 Subsequent myocardial infarction of other sites
0.000 0.755 0.245
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.755 0.245
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.755 0.245
I24.8 Other forms of acute ischaemic heart disease
0.000 0.761 0.239
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.762 0.238
I42.9 Cardiomyopathy, unspecified
0.000 0.763 0.237
I09 Other rheumatic heart diseases
0.000 0.766 0.234
I07 Rheumatic tricuspid valve diseases
0.000 0.766 0.234
I06 Rheumatic aortic valve diseases
0.000 0.766 0.234
I05 Rheumatic mitral valve diseases
0.000 0.766 0.234
I95.8 Other hypotension
0.000 0.771 0.229
I95.2 Hypotension due to drugs
0.000 0.771 0.229
I95.0 Idiopathic hypotension
0.000 0.771 0.229
I78 Diseases of capillaries
0.000 0.776 0.224
I51.9 Heart disease, unspecified
0.000 0.776 0.223
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.777 0.223
I72 Other aneurysm
0.000 0.777 0.223
I70 Atherosclerosis
0.000 0.778 0.222
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.779 0.221
I74 Arterial embolism and thrombosis
0.000 0.780 0.220
I73 Other peripheral vascular diseases
0.000 0.780 0.220
I71 Aortic aneurysm and dissection
0.000 0.783 0.217
I28 Other diseases of pulmonary vessels
0.000 0.783 0.216
I27 Other pulmonary heart diseases
0.000 0.784 0.216
I08 Multiple valve diseases
0.000 0.785 0.215
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.787 0.213
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.791 0.209
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.791 0.209
I49.3 Ventricular premature depolarisation
0.000 0.792 0.208
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.793 0.207
I31.8 Other specified diseases of pericardium
0.000 0.795 0.205
I31.2 Haemopericardium, not elsewhere classified
0.000 0.795 0.205
I31.1 Chronic constrictive pericarditis
0.000 0.795 0.205
I31.0 Chronic adhesive pericarditis
0.000 0.795 0.205
I77 Other disorders of arteries and arterioles
0.000 0.795 0.205
I95.1 Orthostatic hypotension
0.000 0.796 0.204
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.799 0.201
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.799 0.201
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.799 0.201
I98.0 Cardiovascular syphilis
0.000 0.799 0.201
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.804 0.196
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.804 0.196
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.804 0.196
I97.1 Other functional disturbances following cardiac surgery
0.000 0.804 0.196
I97.0 Postcardiotomy syndrome
0.000 0.804 0.196
I60-I69 Cerebrovascular diseases
0.000 0.805 0.195
I44.2 Atrioventricular block, complete
0.001 0.805 0.194
I45.6 Preexcitation syndrome
0.000 0.805 0.194
I12 Hypertensive renal disease
0.000 0.808 0.192
I49.8 Other specified cardiac arrhythmias
0.000 0.809 0.191
I49.2 Junctional premature depolarisation
0.000 0.809 0.190
I49.1 Atrial premature depolarisation
0.000 0.809 0.190
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.816 0.184
I15 Secondary hypertension
0.000 0.821 0.179
I13 Hypertensive heart and renal disease
0.000 0.821 0.179
I11 Hypertensive heart disease
0.000 0.821 0.179
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.822 0.178
I01.8 Other acute rheumatic heart disease
0.000 0.822 0.178
I01.2 Acute rheumatic myocarditis
0.000 0.822 0.178
I01.1 Acute rheumatic endocarditis
0.000 0.822 0.178
I01.0 Acute rheumatic pericarditis
0.000 0.822 0.178
I02.9 Rheumatic chorea without heart involvement
0.000 0.822 0.178
I02.0 Rheumatic chorea with heart involvement
0.000 0.822 0.178
I31.9 Disease of pericardium, unspecified
0.000 0.822 0.177
I26 Pulmonary embolism
0.000 0.826 0.174
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.827 0.173
I51.8 Other ill-defined heart diseases
0.000 0.829 0.171
I21.4 Acute subendocardial myocardial infarction
0.000 0.832 0.168
I05.9 Mitral valve disease, unspecified
0.000 0.832 0.168
I05.8 Other mitral valve diseases
0.000 0.832 0.168
I05.2 Mitral stenosis with insufficiency
0.000 0.832 0.168
I05.1 Rheumatic mitral insufficiency
0.000 0.832 0.168
I05.0 Mitral stenosis
0.000 0.832 0.168
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.832 0.168
I06.8 Other rheumatic aortic valve diseases
0.000 0.832 0.168
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.832 0.168
I06.1 Rheumatic aortic insufficiency
0.000 0.832 0.168
I06.0 Rheumatic aortic stenosis
0.000 0.832 0.168
I07.9 Tricuspid valve disease, unspecified
0.000 0.832 0.168
I07.8 Other tricuspid valve diseases
0.000 0.832 0.168
I07.2 Tricuspid stenosis with insufficiency
0.000 0.832 0.168
I07.1 Tricuspid insufficiency
0.000 0.832 0.168
I07.0 Tricuspid stenosis
0.000 0.832 0.168
I09.9 Rheumatic heart disease, unspecified
0.000 0.832 0.168
I09.8 Other specified rheumatic heart diseases
0.000 0.832 0.168
I09.2 Chronic rheumatic pericarditis
0.000 0.832 0.168
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.832 0.168
I09.0 Rheumatic myocarditis
0.000 0.832 0.168
I49.9 Cardiac arrhythmia, unspecified
0.000 0.832 0.168
I49.0 Ventricular fibrillation and flutter
0.000 0.834 0.166
I49.4 Other and unspecified premature depolarisation
0.000 0.835 0.165
I49.5 Sick sinus syndrome
0.000 0.836 0.164
I31.3 Pericardial effusion (noninflammatory)
0.000 0.837 0.162
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.838 0.162
I78.1 Naevus, nonneoplastic
0.000 0.838 0.162
I78.9 Disease of capillaries, unspecified
0.000 0.839 0.161
I78.8 Other diseases of capillaries
0.000 0.839 0.161
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.839 0.161
I27.2 Other secondary pulmonary hypertension
0.000 0.839 0.161
I72.9 Aneurysm of unspecified site
0.000 0.840 0.160
I72.8 Aneurysm of other specified arteries
0.000 0.840 0.160
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.840 0.160
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.840 0.160
I72.4 Aneurysm of artery of lower extremity
0.000 0.840 0.160
I72.3 Aneurysm of iliac artery
0.000 0.840 0.160
I72.2 Aneurysm of renal artery
0.000 0.840 0.160
I72.1 Aneurysm of artery of upper extremity
0.000 0.840 0.160
I72.0 Aneurysm of carotid artery
0.000 0.840 0.160
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.840 0.160
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.840 0.160
I79.1 Aortitis in diseases classified elsewhere
0.000 0.840 0.160
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.840 0.160
I21.9 Acute myocardial infarction, unspecified
0.000 0.840 0.160
I70.9 Generalised and unspecified atherosclerosis
0.000 0.841 0.159
I70.8 Atherosclerosis of other arteries
0.000 0.841 0.159
I70.1 Atherosclerosis of renal artery
0.000 0.841 0.159
I70.0 Atherosclerosis of aorta
0.000 0.841 0.159
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.841 0.159
I73.9 Peripheral vascular disease, unspecified
0.000 0.841 0.159
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.842 0.158
I74.8 Embolism and thrombosis of other arteries
0.000 0.842 0.158
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.842 0.158
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.842 0.158
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.842 0.158
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.842 0.158
I73.8 Other specified peripheral vascular diseases
0.000 0.842 0.158
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.842 0.158
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.842 0.157
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.843 0.157
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.844 0.156
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.844 0.156
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.844 0.156
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.844 0.156
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.844 0.156
I71.0 Dissection of aorta [any part]
0.000 0.844 0.156
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.844 0.155
I28.8 Other specified diseases of pulmonary vessels
0.000 0.844 0.155
I28.1 Aneurysm of pulmonary artery
0.000 0.844 0.155
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.844 0.155
I27.9 Pulmonary heart disease, unspecified
0.000 0.845 0.155
I27.8 Other specified pulmonary heart diseases
0.000 0.845 0.155
I27.1 Kyphoscoliotic heart disease
0.000 0.845 0.155
I08.9 Multiple valve disease, unspecified
0.000 0.846 0.154
I08.8 Other multiple valve diseases
0.000 0.846 0.154
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.846 0.154
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.846 0.154
I73.0 Raynaud's syndrome
0.000 0.847 0.153
I12.0 Hypertensive renal disease with renal failure
0.000 0.850 0.150
I74.5 Embolism and thrombosis of iliac artery
0.000 0.850 0.150
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.852 0.148
I27.0 Primary pulmonary hypertension
0.000 0.852 0.147
I77.8 Other specified disorders of arteries and arterioles
0.000 0.853 0.147
I77.6 Arteritis, unspecified
0.000 0.853 0.147
I77.5 Necrosis of artery
0.000 0.853 0.147
I77.4 Coeliac artery compression syndrome
0.000 0.853 0.147
I77.3 Arterial fibromuscular dysplasia
0.000 0.853 0.147
I77.2 Rupture of artery
0.000 0.853 0.147
I77.0 Arteriovenous fistula, acquired
0.000 0.853 0.147
I61 Intracerebral haemorrhage
0.000 0.856 0.144
I08.0 Disorders of both mitral and aortic valves
0.000 0.858 0.142
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.858 0.142
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.860 0.140
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.860 0.140
I62 Other nontraumatic intracranial haemorrhage
0.000 0.860 0.140
I63 Cerebral infarction
0.000 0.860 0.139
I69 Sequelae of cerebrovascular disease
0.000 0.861 0.139
I12.9 Hypertensive renal disease without renal failure
0.000 0.862 0.138
I77.1 Stricture of artery
0.000 0.865 0.134
I65.2 Occlusion and stenosis of carotid artery
0.000 0.870 0.130
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.871 0.128
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.871 0.128
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.871 0.128
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.871 0.128
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.871 0.128
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.871 0.128
I15.9 Seconday hypertension, unspecified
0.000 0.871 0.128
I15.8 Other secondary hypertension
0.000 0.871 0.128
I15.2 Hypertension secondary to endocrine disorders
0.000 0.871 0.128
I15.1 Hypertension secondary to other renal disorders
0.000 0.871 0.128
I15.0 Renovascular hypertension
0.000 0.871 0.128
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.875 0.125
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.880 0.120
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.886 0.114
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.886 0.114
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.886 0.114
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.886 0.114
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.886 0.114
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.886 0.114
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.886 0.114
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.886 0.114
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.887 0.113
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.887 0.113
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.887 0.113
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.887 0.113
I65.1 Occlusion and stenosis of basilar artery
0.000 0.887 0.113
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.887 0.113
I63.9 Cerebral infarction, unspecified
0.000 0.888 0.112
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.888 0.112
I60 Subarachnoid haemorrhage
0.001 0.892 0.108
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.893 0.107
I61.8 Other intracerebral haemorrhage
0.000 0.897 0.103
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.897 0.103
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.897 0.103
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.897 0.103
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.897 0.103
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.897 0.103
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.897 0.103
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.897 0.103
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.898 0.102
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.899 0.100
I62.1 Nontraumatic extradural haemorrhage
0.000 0.899 0.100
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.899 0.100
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.899 0.100
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.899 0.100
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.899 0.100
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.899 0.100
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.899 0.100
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.899 0.100
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.899 0.100
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.899 0.100
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.899 0.100
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.899 0.100
I68.0 Cerebral amyloid angiopathy
0.000 0.899 0.100
I63.8 Other cerebral infarction
0.000 0.900 0.100
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.900 0.100
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.900 0.100
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.900 0.100
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.900 0.100
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.900 0.100
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.900 0.100
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.900 0.100
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.900 0.100
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.900 0.100
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.900 0.100
I69.3 Sequelae of cerebral infarction
0.000 0.903 0.097
I67 Other cerebrovascular diseases
0.000 0.908 0.092
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.908 0.092
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.911 0.089
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.918 0.081
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.918 0.082
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.921 0.079
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.922 0.077
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.922 0.077
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.922 0.077
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.922 0.077
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.922 0.077
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.922 0.077
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.922 0.077
I80 Phlebitis and thrombophlebitis
0.000 0.932 0.068
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.001 0.933 0.066
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.934 0.066
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.934 0.066
I67.5 Moyamoya disease
0.000 0.934 0.066
I67.4 Hypertensive encephalopathy
0.000 0.934 0.066
I67.3 Progressive vascular leukoencephalopathy
0.000 0.934 0.066
I67.2 Cerebral atherosclerosis
0.000 0.934 0.066
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.934 0.066
I88 Nonspecific lymphadenitis
0.000 0.934 0.066
I86 Varicose veins of other sites
0.000 0.934 0.066
I82 Other venous embolism and thrombosis
0.000 0.934 0.066
I81 Portal vein thrombosis
0.000 0.934 0.066
I67.8 Other specified cerebrovascular diseases
0.000 0.935 0.065
I87 Other disorders of veins
0.000 0.936 0.064
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.936 0.064
I85 Oesophageal varices
0.000 0.938 0.062
I60.8 Other subarachnoid haemorrhage
0.001 0.939 0.060
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.944 0.056
I67.9 Cerebrovascular disease, unspecified
0.000 0.945 0.054
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.951 0.049
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.951 0.049
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.951 0.049
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.952 0.048
I82.8 Embolism and thrombosis of other specified veins
0.000 0.952 0.048
I82.3 Embolism and thrombosis of renal vein
0.000 0.952 0.048
I82.2 Embolism and thrombosis of vena cava
0.000 0.952 0.048
I82.1 Thrombophlebitis migrans
0.000 0.952 0.048
I82.0 Budd-Chiari syndrome
0.000 0.952 0.048
I86.8 Varicose veins of other specified sites
0.000 0.952 0.048
I86.4 Gastric varices
0.000 0.952 0.048
I86.3 Vulval varices
0.000 0.952 0.048
I86.2 Pelvic varices
0.000 0.952 0.048
I86.1 Scrotal varices
0.000 0.952 0.048
I86.0 Sublingual varices
0.000 0.952 0.048
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.952 0.048
I88.8 Other nonspecific lymphadenitis
0.000 0.952 0.048
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.952 0.048
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.952 0.048
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.953 0.047
I87.9 Disorder of vein, unspecified
0.000 0.954 0.046
I87.8 Other specified disorders of veins
0.000 0.954 0.046
I87.1 Compression of vein
0.000 0.954 0.046
I87.0 Postphlebitic syndrome
0.000 0.954 0.046
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.954 0.046
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.954 0.046
I89.1 Lymphangitis
0.000 0.954 0.046
I10 Essential (primary) hypertension
0.000 0.954 0.046
I85.0 Oesophageal varices with bleeding
0.000 0.955 0.045
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.955 0.044
I67.1 Cerebral aneurysm, nonruptured
0.001 0.956 0.044
I89.0 Lymphoedema, not elsewhere classified
0.000 0.956 0.044
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.957 0.043
I85.9 Oesophageal varices without bleeding
0.000 0.960 0.040
I83 Varicose veins of lower extremities
0.000 0.972 0.028
N81.1 Cystocele
0.027 0.973 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.979 0.020
I83.0 Varicose veins of lower extremities with ulcer
0.001 0.982 0.018
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.982 0.017
Z85.4 Personal history of malignant neoplasm of genital organs
0.000 0.988 0.012
N81 Female genital prolapse
0.011 0.989 0.000
N81.6 Rectocele
0.009 0.991 0.000
N81.8 Other female genital prolapse
0.009 0.991 0.000
N81.9 Female genital prolapse, unspecified
0.009 0.991 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.008 0.992 0.000
N81.0 Female urethrocele
0.008 0.992 0.000
N81.5 Vaginal enterocele
0.007 0.992 0.000
N81.3 Complete uterovaginal prolapse
0.007 0.993 0.000
N81.2 Incomplete uterovaginal prolapse
0.007 0.993 0.000
N81.4 Uterovaginal prolapse, unspecified
0.006 0.993 0.000
N89 Other noninflammatory disorders of vagina
0.005 0.995 0.000
C61 Malignant neoplasm of prostate
0.000 0.996 0.004
N89.9 Noninflammatory disorder of vagina, unspecified
0.004 0.996 0.000
N89.7 Haematocolpos
0.004 0.996 0.000
N89.6 Tight hymenal ring
0.004 0.996 0.000
N89.5 Stricture and atresia of vagina
0.004 0.996 0.000
N89.4 Leukoplakia of vagina
0.004 0.996 0.000
N89.3 Dysplasia of vagina, unspecified
0.004 0.996 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.004 0.996 0.000
N89.1 Moderate vaginal dysplasia
0.004 0.996 0.000
N89.0 Mild vaginal dysplasia
0.004 0.996 0.000
K83.8 Other specified diseases of biliary tract
0.003 0.996 0.000
Z85 Personal history of malignant neoplasm
0.000 0.997 0.003
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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