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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4757833
log Bayes Factor = 0.739549
Chromosome 11   position 19,663,278  (GRCh37) Explore rs4757833 on Ensembl!
Variant rs4757833 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.816 0.184 0.000
Chapter XI Diseases of the digestive system
0.801 0.199 0.000
Chapter I Certain infectious and parasitic diseases
0.784 0.216 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.780 0.220 0.000
Chapter XIV Diseases of the genitourinary system
0.778 0.222 0.000
K55-K64 Other diseases of intestines
0.777 0.223 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.776 0.224 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.756 0.244 0.000
K80 Cholelithiasis
0.745 0.255 0.000
K62 Other diseases of anus and rectum
0.726 0.274 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.719 0.281 0.000
B95-B98 Bacterial, viral and other infectious agents
0.705 0.295 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.695 0.305 0.000
R50-R69 General symptoms and signs
0.692 0.308 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.690 0.310 0.000
K57 Diverticular disease of intestine
0.685 0.315 0.000
Chapter XX External causes of morbidity and mortality
0.677 0.323 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.668 0.332 0.000
K63 Other diseases of intestine
0.668 0.332 0.000
K81 Cholecystitis
0.666 0.334 0.000
S00-S09 Injuries to the head
0.660 0.340 0.000
A00-A09 Intestinal infectious diseases
0.656 0.344 0.000
K62.5 Haemorrhage of anus and rectum
0.655 0.345 0.000
N40-N51 Diseases of male genital organs
0.653 0.347 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.650 0.350 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.649 0.351 0.000
A30-A49 Other bacterial diseases
0.645 0.355 0.000
Chapter VII Diseases of the eye and adnexa
0.641 0.359 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.639 0.361 0.000
N10-N16 Renal tubulo-interstitial diseases
0.637 0.363 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.635 0.365 0.000
Chapter V Mental and behavioural disorders
0.632 0.368 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.630 0.370 0.000
N20-N23 Urolithiasis
0.627 0.373 0.000
Chapter X Diseases of the respiratory system
0.623 0.377 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.619 0.381 0.000
N92 Excessive, frequent and irregular menstruation
0.618 0.382 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.618 0.382 0.000
R94 Abnormal results of function studies
0.616 0.384 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.616 0.384 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.614 0.386 0.000
B25-B34 Other viral diseases
0.607 0.393 0.000
N84 Polyp of female genital tract
0.605 0.395 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.600 0.399 0.000
K82 Other diseases of gallbladder
0.597 0.403 0.000
R69 Unknown and unspecified causes of morbidity
0.590 0.410 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.589 0.411 0.000
K62.3 Rectal prolapse
0.588 0.412 0.000
K35-K38 Diseases of appendix
0.587 0.413 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.586 0.414 0.000
Chapter XXII Codes for special purposes
0.585 0.415 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.585 0.415 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.585 0.415 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.584 0.416 0.000
R47-R49 Symptoms and signs involving speech and voice
0.583 0.416 0.000
K62.1 Rectal polyp
0.581 0.418 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.579 0.421 0.000
S80-S89 Injuries to the knee and lower leg
0.574 0.425 0.000
K65-K67 Diseases of peritoneum
0.573 0.427 0.000
K63.5 Polyp of colon
0.571 0.429 0.000
E10-E14 Diabetes mellitus
0.570 0.430 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.566 0.434 0.000
Chapter VIII Diseases of the ear and mastoid process
0.565 0.434 0.000
S20-S29 Injuries to the thorax
0.565 0.435 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.563 0.437 0.000
S50-S59 Injuries to the elbow and forearm
0.563 0.437 0.000
B99-B99 Other infectious diseases
0.562 0.438 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.562 0.438 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.562 0.438 0.000
B65-B83 Helminthiases
0.562 0.438 0.000
B50-B64 Protozoal diseases
0.562 0.438 0.000
B35-B49 Mycoses
0.562 0.438 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.562 0.438 0.000
B15-B19 Viral hepatitis
0.562 0.438 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.562 0.438 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.562 0.438 0.000
A80-A89 Viral infections of the central nervous system
0.562 0.438 0.000
A75-A79 Rickettsioses
0.562 0.438 0.000
A70-A74 Other diseases caused by chlamydiae
0.562 0.438 0.000
A65-A69 Other spirochaetal diseases
0.562 0.438 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.562 0.438 0.000
A20-A28 Certain zoonotic bacterial diseases
0.562 0.438 0.000
A15-A19 Tuberculosis
0.562 0.438 0.000
S00 Superficial injury of head
0.560 0.440 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.559 0.440 0.000
K86 Other diseases of pancreas
0.559 0.440 0.000
K85 Acute pancreatitis
0.559 0.440 0.000
K83 Other diseases of biliary tract
0.559 0.440 0.000
R79 Other abnormal findings of blood chemistry
0.559 0.440 0.000
N99-N99 Other disorders of the genitourinary system
0.558 0.442 0.000
N25-N29 Other disorders of kidney and ureter
0.558 0.442 0.000
N00-N08 Glomerular diseases
0.558 0.442 0.000
N17-N19 Renal failure
0.557 0.443 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.557 0.443 0.000
K61 Abscess of anal and rectal regions
0.557 0.443 0.000
K55 Vascular disorders of intestine
0.557 0.443 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.556 0.444 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.556 0.444 0.000
A04 Other bacterial intestinal infections
0.556 0.444 0.000
K81.1 Chronic cholecystitis
0.553 0.447 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.551 0.448 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.551 0.449 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.551 0.449 0.000
K60 Fissure and fistula of anal and rectal regions
0.550 0.449 0.000
K70-K77 Diseases of liver
0.550 0.450 0.000
N80 Endometriosis
0.547 0.453 0.000
S70-S79 Injuries to the hip and thigh
0.546 0.454 0.000
A41 Other septicaemia
0.545 0.455 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.545 0.455 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.543 0.456 0.000
N93 Other abnormal uterine and vaginal bleeding
0.543 0.457 0.000
R94.5 Abnormal results of liver function studies
0.543 0.457 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.542 0.458 0.000
T79-T79 Certain early complications of trauma
0.542 0.458 0.000
T66-T78 Other and unspecified effects of external causes
0.542 0.458 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.542 0.458 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.542 0.458 0.000
T33-T35 Frostbite
0.542 0.458 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.542 0.458 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.542 0.458 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.542 0.458 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.542 0.458 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.542 0.458 0.000
T00-T07 Injuries involving multiple body regions
0.542 0.458 0.000
S90-S99 Injuries to the ankle and foot
0.542 0.458 0.000
S40-S49 Injuries to the shoulder and upper arm
0.542 0.458 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.542 0.458 0.000
S10-S19 Injuries to the neck
0.542 0.458 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.541 0.459 0.000
N86 Erosion and ectropion of cervix uteri
0.540 0.460 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.540 0.460 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.540 0.460 0.000
K63.3 Ulcer of intestine
0.540 0.460 0.000
N84.0 Polyp of corpus uteri
0.538 0.462 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.538 0.462 0.000
R51 Headache
0.538 0.462 0.000
Chapter II Neoplasms
0.538 0.462 0.000
R53 Malaise and fatigue
0.537 0.463 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.535 0.465 0.000
R30-R39 Symptoms and signs involving the urinary system
0.534 0.466 0.000
K80.3 Calculus of bile duct with cholangitis
0.534 0.466 0.000
K80.8 Other cholelithiasis
0.534 0.466 0.000
K80.4 Calculus of bile duct with cholecystitis
0.534 0.466 0.000
N41 Inflammatory diseases of prostate
0.534 0.466 0.000
S60-S69 Injuries to the wrist and hand
0.533 0.467 0.000
K81.0 Acute cholecystitis
0.529 0.471 0.000
T81 Complications of procedures, not elsewhere classified
0.528 0.472 0.000
N60-N64 Disorders of breast
0.527 0.473 0.000
R50 Fever of unknown origin
0.524 0.476 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.523 0.477 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.523 0.477 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.522 0.478 0.000
N13 Obstructive and reflux uropathy
0.522 0.478 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.522 0.478 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.522 0.478 0.000
K62.9 Disease of anus and rectum, unspecified
0.521 0.479 0.000
K62.7 Radiation proctitis
0.521 0.479 0.000
K62.6 Ulcer of anus and rectum
0.521 0.479 0.000
K62.4 Stenosis of anus and rectum
0.521 0.479 0.000
K62.2 Anal prolapse
0.521 0.479 0.000
K62.0 Anal polyp
0.521 0.479 0.000
Chapter VI Diseases of the nervous system
0.519 0.481 0.000
S01 Open wound of head
0.517 0.483 0.000
K04 Diseases of pulp and periapical tissues
0.516 0.484 0.000
R63 Symptoms and signs concerning food and fluid intake
0.516 0.484 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.515 0.484 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.515 0.484 0.000
N23 Unspecified renal colic
0.515 0.485 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.513 0.487 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.512 0.488 0.000
J95-J99 Other diseases of the respiratory system
0.505 0.495 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.505 0.495 0.000
K62.8 Other specified diseases of anus and rectum
0.504 0.496 0.000
R05 Cough
0.503 0.497 0.000
J90-J94 Other diseases of pleura
0.500 0.500 0.000
N98 Complications associated with artificial fertilisation
0.499 0.501 0.000
N97 Female infertility
0.499 0.501 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.499 0.501 0.000
N91 Absent, scanty and rare menstruation
0.499 0.501 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.499 0.501 0.000
N88 Other noninflammatory disorders of cervix uteri
0.499 0.501 0.000
N87 Dysplasia of cervix uteri
0.499 0.501 0.000
N82 Fistulae involving female genital tract
0.499 0.501 0.000
N96 Habitual aborter
0.499 0.501 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.499 0.501 0.000
N89 Other noninflammatory disorders of vagina
0.497 0.503 0.000
L60-L75 Disorders of skin appendages
0.496 0.503 0.000
R68 Other general symptoms and signs
0.496 0.503 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.496 0.503 0.000
R62 Lack of expected normal physiological development
0.496 0.503 0.000
R61 Hyperhidrosis
0.496 0.503 0.000
R60 Oedema, not elsewhere classified
0.496 0.503 0.000
R59 Enlarged lymph nodes
0.496 0.503 0.000
R57 Shock, not elsewhere classified
0.496 0.503 0.000
R56 Convulsions, not elsewhere classified
0.496 0.503 0.000
R52 Pain, not elsewhere classified
0.496 0.503 0.000
R64 Cachexia
0.496 0.503 0.000
R58 Haemorrhage, not elsewhere classified
0.496 0.503 0.000
R54 Senility
0.496 0.503 0.000
E11 Non-insulin-dependent diabetes mellitus
0.496 0.504 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.495 0.505 0.000
O00-O08 Pregnancy with abortive outcome
0.492 0.508 0.000
S09 Other and unspecified injuries of head
0.492 0.508 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.491 0.508 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.491 0.508 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.491 0.508 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.491 0.508 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.491 0.508 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.491 0.508 0.000
O60-O75 Complications of labour and delivery
0.491 0.509 0.000
N50 Other disorders of male genital organs
0.490 0.509 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.487 0.513 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.487 0.513 0.000
K40-K46 Hernia
0.486 0.514 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.485 0.515 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.485 0.515 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.485 0.515 0.000
Y35-Y36 Legal intervention and operations of war
0.485 0.515 0.000
Y10-Y34 Event of undetermined intent
0.485 0.515 0.000
Y00-Y09 Assault
0.485 0.515 0.000
X85-X99 Assault
0.485 0.515 0.000
X60-X84 Intentional self-harm
0.485 0.515 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.485 0.515 0.000
X50-X57 Overexertion, travel and privation
0.485 0.515 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.485 0.515 0.000
X30-X39 Exposure to forces of nature
0.485 0.515 0.000
X20-X29 Contact with venomous animals and plants
0.485 0.515 0.000
X10-X19 Contact with heat and hot substances
0.485 0.515 0.000
X00-X09 Exposure to smoke, fire and flames
0.485 0.515 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.485 0.515 0.000
W75-W84 Other accidental threats to breathing
0.485 0.515 0.000
W65-W74 Accidental drowning and submersion
0.485 0.515 0.000
W50-W64 Exposure to animate mechanical forces
0.485 0.515 0.000
W20-W49 Exposure to inanimate mechanical forces
0.485 0.515 0.000
V98-V99 Other and unspecified transport accidents
0.485 0.515 0.000
V95-V97 Air and space transport accidents
0.485 0.515 0.000
V90-V94 Water transport accidents
0.485 0.515 0.000
V80-V89 Other land transport accidents
0.485 0.515 0.000
V70-V79 Bus occupant injured in transport accident
0.485 0.515 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.485 0.515 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.485 0.515 0.000
V40-V49 Car occupant injured in transport accident
0.485 0.515 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.485 0.515 0.000
V20-V29 Motorcycle rider injured in transport accident
0.485 0.515 0.000
V10-V19 Pedal cyclist injured in transport accident
0.485 0.515 0.000
V01-V09 Pedestrian injured in transport accident
0.485 0.515 0.000
N43 Hydrocele and spermatocele
0.485 0.515 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.484 0.516 0.000
K59 Other functional intestinal disorders
0.483 0.517 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.482 0.518 0.000
N30-N39 Other diseases of urinary system
0.481 0.518 0.000
B34 Viral infection of unspecified site
0.480 0.520 0.000
S00.9 Superficial injury of head, part unspecified
0.479 0.520 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.479 0.521 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.479 0.521 0.000
O85-O92 Complications predominantly related to the puerperium
0.479 0.521 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.479 0.521 0.000
K63.9 Disease of intestine, unspecified
0.479 0.521 0.000
K63.4 Enteroptosis
0.479 0.521 0.000
K63.2 Fistula of intestine
0.479 0.521 0.000
K63.1 Perforation of intestine (nontraumatic)
0.479 0.521 0.000
K63.0 Abscess of intestine
0.479 0.521 0.000
K81.9 Cholecystitis, unspecified
0.477 0.522 0.000
K81.8 Other cholecystitis
0.477 0.522 0.000
E00-E07 Disorders of thyroid gland
0.477 0.523 0.000
H40-H42 Glaucoma
0.475 0.525 0.000
F30-F39 Mood [affective] disorders
0.474 0.526 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.474 0.526 0.000
A41.9 Septicaemia, unspecified
0.474 0.526 0.000
S08 Traumatic amputation of part of head
0.473 0.527 0.000
S07 Crushing injury of head
0.473 0.527 0.000
S06 Intracranial injury
0.473 0.527 0.000
S05 Injury of eye and orbit
0.473 0.527 0.000
S04 Injury of cranial nerves
0.473 0.527 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.473 0.527 0.000
S02 Fracture of skull and facial bones
0.473 0.527 0.000
O80-O84 Delivery
0.473 0.527 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.473 0.527 0.000
J40-J47 Chronic lower respiratory diseases
0.470 0.530 0.000
A08 Viral and other specified intestinal infections
0.470 0.530 0.000
A07 Other protozoal intestinal diseases
0.470 0.530 0.000
A06 Amoebiasis
0.470 0.530 0.000
A05 Other bacterial foodborne intoxications
0.470 0.530 0.000
A03 Shigellosis
0.470 0.530 0.000
A02 Other Salmonella infections
0.470 0.530 0.000
A01 Typhoid and paratyphoid fevers
0.470 0.530 0.000
A00 Cholera
0.470 0.530 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.468 0.532 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.468 0.532 0.000
N48 Other disorders of penis
0.468 0.532 0.000
N45 Orchitis and epididymitis
0.468 0.532 0.000
N42 Other disorders of prostate
0.468 0.532 0.000
N46 Male infertility
0.468 0.532 0.000
N44 Torsion of testis
0.468 0.532 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.468 0.532 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.466 0.534 0.000
R77 Other abnormalities of plasma proteins
0.466 0.534 0.000
R76 Other abnormal immunological findings in serum
0.466 0.534 0.000
R74 Abnormal serum enzyme levels
0.466 0.534 0.000
R73 Elevated blood glucose level
0.466 0.534 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.466 0.534 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.466 0.534 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.466 0.534 0.000
R71 Abnormality of red blood cells
0.466 0.534 0.000
N92.6 Irregular menstruation, unspecified
0.466 0.534 0.000
K58 Irritable bowel syndrome
0.465 0.534 0.000
L40-L45 Papulosquamous disorders
0.465 0.535 0.000
L50-L54 Urticaria and erythema
0.465 0.535 0.000
L20-L30 Dermatitis and eczema
0.465 0.535 0.000
L10-L14 Bullous disorders
0.465 0.535 0.000
K82.8 Other specified diseases of gallbladder
0.465 0.535 0.000
H30-H36 Disorders of choroid and retina
0.465 0.535 0.000
N92.3 Ovulation bleeding
0.462 0.537 0.000
A49 Bacterial infection of unspecified site
0.462 0.538 0.000
A48 Other bacterial diseases, not elsewhere classified
0.462 0.538 0.000
A44 Bartonellosis
0.462 0.538 0.000
A43 Nocardiosis
0.462 0.538 0.000
A42 Actinomycosis
0.462 0.538 0.000
A40 Streptococcal septicaemia
0.462 0.538 0.000
A39 Meningococcal infection
0.462 0.538 0.000
A37 Whooping cough
0.462 0.538 0.000
A36 Diphtheria
0.462 0.538 0.000
A32 Listeriosis
0.462 0.538 0.000
A31 Infection due to other mycobacteria
0.462 0.538 0.000
A30 Leprosy [Hansen's disease]
0.462 0.538 0.000
A46 Erysipelas
0.462 0.538 0.000
A38 Scarlet fever
0.462 0.538 0.000
A35 Other tetanus
0.462 0.538 0.000
A34 Obstetrical tetanus
0.462 0.538 0.000
A33 Tetanus neonatorum
0.462 0.538 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.462 0.538 0.000
E10 Insulin-dependent diabetes mellitus
0.460 0.540 0.000
H55-H59 Other disorders of eye and adnexa
0.460 0.540 0.000
H53-H54 Visual disturbances and blindness
0.460 0.540 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.460 0.540 0.000
H43-H45 Disorders of vitreous body and globe
0.460 0.540 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.460 0.540 0.000
H10-H13 Disorders of conjunctiva
0.460 0.540 0.000
E50-E64 Other nutritional deficiencies
0.458 0.541 0.000
E40-E46 Malnutrition
0.458 0.541 0.000
E20-E35 Disorders of other endocrine glands
0.458 0.541 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.458 0.541 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.458 0.542 0.000
J30-J39 Other diseases of upper respiratory tract
0.457 0.542 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.457 0.543 0.000
N15 Other renal tubulo-interstitial diseases
0.457 0.543 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.457 0.543 0.000
N11 Chronic tubulo-interstitial nephritis
0.457 0.543 0.000
N10 Acute tubulo-interstitial nephritis
0.457 0.543 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.456 0.543 0.000
W00-W19 Falls
0.456 0.543 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.456 0.544 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.455 0.544 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.455 0.544 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.455 0.544 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.455 0.544 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.455 0.544 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.455 0.544 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.455 0.544 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.455 0.545 0.000
N20 Calculus of kidney and ureter
0.455 0.545 0.000
O47 False labour
0.454 0.545 0.000
R55 Syncope and collapse
0.455 0.545 0.000
F99-F99 Unspecified mental disorder
0.453 0.547 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.453 0.547 0.000
F80-F89 Disorders of psychological development
0.453 0.547 0.000
F70-F79 Mental retardation
0.453 0.547 0.000
F60-F69 Disorders of adult personality and behaviour
0.453 0.547 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.453 0.547 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.453 0.547 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.453 0.547 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.453 0.547 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.452 0.548 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.452 0.548 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.451 0.549 0.000
K90-K93 Other diseases of the digestive system
0.451 0.549 0.000
K50-K52 Noninfective enteritis and colitis
0.450 0.550 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.449 0.550 0.000
N21 Calculus of lower urinary tract
0.449 0.550 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.449 0.551 0.000
A04.8 Other specified bacterial intestinal infections
0.449 0.551 0.000
N73 Other female pelvic inflammatory diseases
0.448 0.552 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.448 0.552 0.000
K01 Embedded and impacted teeth
0.447 0.552 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.447 0.553 0.000
D10-D36 Benign neoplasms
0.447 0.553 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.447 0.553 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.447 0.553 0.000
J60-J70 Lung diseases due to external agents
0.447 0.553 0.000
J00-J06 Acute upper respiratory infections
0.447 0.553 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.446 0.554 0.000
R47 Speech disturbances, not elsewhere classified
0.445 0.554 0.000
K04.7 Periapical abscess without sinus
0.445 0.555 0.000
S82 Fracture of lower leg, including ankle
0.444 0.555 0.000
D50-D53 Nutritional anaemias
0.444 0.556 0.000
Y83.8 Other surgical procedures
0.443 0.557 0.000
N92.5 Other specified irregular menstruation
0.443 0.557 0.000
N92.4 Excessive bleeding in the premenopausal period
0.443 0.557 0.000
N92.2 Excessive menstruation at puberty
0.443 0.557 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.443 0.557 0.000
T87 Complications peculiar to reattachment and amputation
0.443 0.557 0.000
T86 Failure and rejection of transplanted organs and tissues
0.443 0.557 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.443 0.557 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.443 0.557 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.443 0.557 0.000
E11.9 Without complications
0.442 0.558 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.442 0.558 0.000
R94.7 Abnormal results of other endocrine function studies
0.442 0.558 0.000
R94.6 Abnormal results of thyroid function studies
0.442 0.558 0.000
R94.4 Abnormal results of kidney function studies
0.442 0.558 0.000
R94.3 Abnormal results of cardiovascular function studies
0.442 0.558 0.000
R94.2 Abnormal results of pulmonary function studies
0.442 0.558 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.442 0.558 0.000
R94.0 Abnormal results of function studies of central nervous system
0.442 0.558 0.000
K14 Diseases of tongue
0.442 0.558 0.000
K12 Stomatitis and related lesions
0.442 0.558 0.000
K11 Diseases of salivary glands
0.442 0.558 0.000
K10 Other diseases of jaws
0.442 0.558 0.000
K09 Cysts of oral region, not elsewhere classified
0.442 0.558 0.000
K07 Dentofacial anomalies [including malocclusion]
0.442 0.558 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.442 0.558 0.000
K05 Gingivitis and periodontal diseases
0.442 0.558 0.000
K03 Other diseases of hard tissues of teeth
0.442 0.558 0.000
K00 Disorders of tooth development and eruption
0.442 0.558 0.000
N84.1 Polyp of cervix uteri
0.441 0.559 0.000
K63.8 Other specified diseases of intestine
0.441 0.559 0.000
N80.0 Endometriosis of uterus
0.441 0.559 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.441 0.559 0.000
D80-D89 Certain disorders involving the immune mechanism
0.440 0.560 0.000
D55-D59 Haemolytic anaemias
0.440 0.560 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.439 0.561 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.437 0.563 0.000
B33 Other viral diseases, not elsewhere classified
0.435 0.565 0.000
B30 Viral conjunctivitis
0.435 0.565 0.000
B27 Infectious mononucleosis
0.435 0.565 0.000
B26 Mumps
0.435 0.565 0.000
B25 Cytomegaloviral disease
0.435 0.565 0.000
N84.9 Polyp of female genital tract, unspecified
0.434 0.566 0.000
N84.8 Polyp of other parts of female genital tract
0.434 0.566 0.000
N84.3 Polyp of vulva
0.434 0.566 0.000
N84.2 Polyp of vagina
0.434 0.566 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.433 0.567 0.000
K35 Acute appendicitis
0.433 0.567 0.000
H02 Other disorders of eyelid
0.432 0.568 0.000
N17 Acute renal failure
0.432 0.568 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.431 0.569 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.431 0.569 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.431 0.569 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.431 0.569 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.431 0.569 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.431 0.569 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.431 0.569 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.429 0.571 0.000
K82.9 Disease of gallbladder, unspecified
0.428 0.572 0.000
K82.4 Cholesterolosis of gallbladder
0.428 0.572 0.000
K82.3 Fistula of gallbladder
0.428 0.572 0.000
K82.2 Perforation of gallbladder
0.428 0.572 0.000
K82.1 Hydrops of gallbladder
0.428 0.572 0.000
K82.0 Obstruction of gallbladder
0.428 0.572 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.427 0.573 0.000
S52 Fracture of forearm
0.425 0.575 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.424 0.576 0.000
K02 Dental caries
0.423 0.576 0.000
K08 Other disorders of teeth and supporting structures
0.422 0.578 0.000
J98 Other respiratory disorders
0.421 0.579 0.000
K38 Other diseases of appendix
0.421 0.579 0.000
K37 Unspecified appendicitis
0.421 0.579 0.000
K36 Other appendicitis
0.421 0.579 0.000
Y83.6 Removal of other organ (partial) (total)
0.421 0.579 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.420 0.580 0.000
N76 Other inflammation of vagina and vulva
0.420 0.580 0.000
N75 Diseases of Bartholin's gland
0.420 0.580 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.420 0.580 0.000
N71 Inflammatory disease of uterus, except cervix
0.420 0.580 0.000
N70 Salpingitis and oophoritis
0.420 0.580 0.000
N72 Inflammatory disease of cervix uteri
0.420 0.580 0.000
R33 Retention of urine
0.420 0.580 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.420 0.580 0.000
K13 Other diseases of lip and oral mucosa
0.419 0.580 0.000
P90-P96 Other disorders originating in the perinatal period
0.419 0.580 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.419 0.580 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.419 0.580 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.419 0.580 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.419 0.580 0.000
P35-P39 Infections specific to the perinatal period
0.419 0.580 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.419 0.580 0.000
P10-P15 Birth trauma
0.419 0.580 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.419 0.580 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.419 0.580 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.419 0.580 0.000
Q80-Q89 Other congenital malformations
0.419 0.580 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.419 0.580 0.000
Q60-Q64 Congenital malformations of the urinary system
0.419 0.580 0.000
Q50-Q56 Congenital malformations of genital organs
0.419 0.580 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.419 0.580 0.000
Q35-Q37 Cleft lip and cleft palate
0.419 0.580 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.419 0.580 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.419 0.580 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.419 0.580 0.000
Q00-Q07 Congenital malformations of the nervous system
0.419 0.580 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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