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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4773330
log Bayes Factor = 0.369987
Chromosome 13   position 111,818,832  (GRCh37) Explore rs4773330 on Ensembl!
Variant rs4773330 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I51.8 Other ill-defined heart diseases
0.000 0.457 0.543
I51 Complications and ill-defined descriptions of heart disease
0.000 0.466 0.534
I51.7 Cardiomegaly
0.000 0.501 0.499
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.561 0.439
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.567 0.433
I30-I52 Other forms of heart disease
0.000 0.576 0.424
I45 Other conduction disorders
0.000 0.589 0.411
I51.6 Cardiovascular disease, unspecified
0.000 0.591 0.409
I47 Paroxysmal tachycardia
0.000 0.598 0.402
I42 Cardiomyopathy
0.000 0.599 0.401
I47.2 Ventricular tachycardia
0.000 0.600 0.400
I45.1 Other and unspecified right bundle-branch block
0.000 0.600 0.400
I51.4 Myocarditis, unspecified
0.000 0.601 0.399
I51.9 Heart disease, unspecified
0.000 0.607 0.393
I51.5 Myocardial degeneration
0.000 0.613 0.387
I51.0 Cardiac septal defect, acquired
0.000 0.616 0.384
I42.9 Cardiomyopathy, unspecified
0.000 0.617 0.383
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.617 0.383
I42.2 Other hypertrophic cardiomyopathy
0.000 0.636 0.364
I50 Heart failure
0.000 0.639 0.361
I45.9 Conduction disorder, unspecified
0.000 0.641 0.359
I45.2 Bifascicular block
0.000 0.651 0.349
I42.6 Alcoholic cardiomyopathy
0.000 0.666 0.334
I45.5 Other specified heart block
0.000 0.676 0.324
I50.1 Left ventricular failure
0.000 0.681 0.319
I40 Acute myocarditis
0.000 0.682 0.318
I50.0 Congestive heart failure
0.000 0.690 0.310
I52 Other heart disorders in diseases classified elsewhere
0.000 0.696 0.304
I48 Atrial fibrillation and flutter
0.000 0.696 0.304
I41 Myocarditis in diseases classified elsewhere
0.000 0.696 0.304
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.696 0.304
I32 Pericarditis in diseases classified elsewhere
0.000 0.696 0.304
I45.8 Other specified conduction disorders
0.000 0.701 0.299
I44 Atrioventricular and left bundle-branch block
0.000 0.708 0.292
I45.0 Right fascicular block
0.000 0.708 0.292
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.712 0.288
I37 Pulmonary valve disorders
0.000 0.714 0.286
I36 Nonrheumatic tricuspid valve disorders
0.000 0.721 0.279
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.723 0.277
I30 Acute pericarditis
0.000 0.723 0.276
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.724 0.276
I42.5 Other restrictive cardiomyopathy
0.000 0.724 0.275
I42.4 Endocardial fibroelastosis
0.000 0.727 0.273
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.730 0.270
I45.3 Trifascicular block
0.000 0.730 0.269
I33 Acute and subacute endocarditis
0.000 0.736 0.264
I47.0 Reentry ventricular arrhythmia
0.000 0.740 0.260
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.742 0.258
I05-I09 Chronic rheumatic heart diseases
0.000 0.755 0.245
I40.0 Infective myocarditis
0.000 0.758 0.241
I08 Multiple valve diseases
0.000 0.759 0.241
I44.0 Atrioventricular block, first degree
0.000 0.761 0.239
Chapter IX Diseases of the circulatory system
0.000 0.761 0.239
I40.9 Acute myocarditis, unspecified
0.000 0.772 0.228
I40.8 Other acute myocarditis
0.000 0.772 0.228
I40.1 Isolated myocarditis
0.000 0.772 0.228
I38 Endocarditis, valve unspecified
0.000 0.773 0.227
I08.0 Disorders of both mitral and aortic valves
0.000 0.776 0.224
I44.4 Left anterior fascicular block
0.000 0.778 0.222
I45.4 Nonspecific intraventricular block
0.000 0.779 0.221
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.780 0.220
I34 Nonrheumatic mitral valve disorders
0.000 0.781 0.219
I44.3 Other and unspecified atrioventricular block
0.000 0.781 0.219
I44.1 Atrioventricular block, second degree
0.000 0.781 0.219
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.782 0.218
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.782 0.218
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.782 0.218
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.782 0.218
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.782 0.218
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.782 0.218
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.782 0.218
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.782 0.218
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.782 0.218
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.782 0.218
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.782 0.218
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.782 0.218
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.782 0.218
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.782 0.218
I48.4 Atypical atrial flutter
0.000 0.782 0.218
I48.3 Typical atrial flutter
0.000 0.782 0.218
I48.2 Chronic atrial fibrillation
0.000 0.782 0.218
I48.1 Persistent atrial fibrillation
0.000 0.782 0.218
I48.0 Paroxysmal atrial fibrillation
0.000 0.782 0.218
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.782 0.218
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.782 0.218
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.782 0.218
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.783 0.217
I06 Rheumatic aortic valve diseases
0.000 0.789 0.211
I44.5 Left posterior fascicular block
0.000 0.790 0.209
I42.0 Dilated cardiomyopathy
0.000 0.791 0.209
I07 Rheumatic tricuspid valve diseases
0.000 0.791 0.209
I44.2 Atrioventricular block, complete
0.000 0.792 0.208
I71 Aortic aneurysm and dissection
0.000 0.794 0.206
I37.9 Pulmonary valve disorder, unspecified
0.000 0.795 0.205
I37.8 Other pulmonary valve disorders
0.000 0.795 0.205
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.795 0.205
I42.8 Other cardiomyopathies
0.000 0.797 0.202
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.800 0.200
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.800 0.200
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.800 0.200
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.800 0.200
I30.8 Other forms of acute pericarditis
0.000 0.800 0.200
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.801 0.199
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.802 0.198
I37.0 Pulmonary valve stenosis
0.000 0.803 0.197
I37.1 Pulmonary valve insufficiency
0.000 0.804 0.196
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.805 0.195
I33.9 Acute endocarditis, unspecified
0.000 0.805 0.195
I05 Rheumatic mitral valve diseases
0.000 0.805 0.195
I71.0 Dissection of aorta [any part]
0.000 0.806 0.194
I31 Other diseases of pericardium
0.000 0.809 0.191
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.809 0.191
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.809 0.191
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.813 0.187
I30.1 Infective pericarditis
0.000 0.814 0.186
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.814 0.186
I09 Other rheumatic heart diseases
0.000 0.815 0.185
I07.1 Tricuspid insufficiency
0.000 0.817 0.183
I30.9 Acute pericarditis, unspecified
0.000 0.818 0.182
I08.9 Multiple valve disease, unspecified
0.000 0.818 0.182
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.819 0.181
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.819 0.181
I06.0 Rheumatic aortic stenosis
0.000 0.821 0.179
I05.9 Mitral valve disease, unspecified
0.000 0.822 0.178
I74 Arterial embolism and thrombosis
0.000 0.822 0.178
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.823 0.177
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.824 0.175
I44.7 Left bundle-branch block, unspecified
0.000 0.827 0.173
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.827 0.173
I49 Other cardiac arrhythmias
0.000 0.828 0.172
I00-I02 Acute rheumatic fever
0.000 0.829 0.171
I06.1 Rheumatic aortic insufficiency
0.000 0.831 0.169
I26 Pulmonary embolism
0.000 0.832 0.168
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.833 0.167
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.833 0.167
I73 Other peripheral vascular diseases
0.000 0.835 0.165
I49.4 Other and unspecified premature depolarisation
0.000 0.839 0.161
I45.6 Preexcitation syndrome
0.000 0.839 0.160
I77 Other disorders of arteries and arterioles
0.000 0.840 0.160
I46 Cardiac arrest
0.000 0.842 0.158
I70 Atherosclerosis
0.000 0.843 0.157
I08.8 Other multiple valve diseases
0.000 0.844 0.156
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.844 0.156
I47.1 Supraventricular tachycardia
0.000 0.844 0.156
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.845 0.155
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.846 0.154
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.847 0.153
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.848 0.152
I06.8 Other rheumatic aortic valve diseases
0.000 0.848 0.152
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.849 0.151
I07.9 Tricuspid valve disease, unspecified
0.000 0.850 0.150
I07.8 Other tricuspid valve diseases
0.000 0.850 0.150
I07.2 Tricuspid stenosis with insufficiency
0.000 0.850 0.150
I07.0 Tricuspid stenosis
0.000 0.850 0.150
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.851 0.149
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.852 0.148
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.852 0.148
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.855 0.145
I44.6 Other and unspecified fascicular block
0.000 0.856 0.144
I09.9 Rheumatic heart disease, unspecified
0.000 0.858 0.142
I05.1 Rheumatic mitral insufficiency
0.000 0.859 0.140
I05.8 Other mitral valve diseases
0.000 0.860 0.140
I33.0 Acute and subacute infective endocarditis
0.000 0.861 0.139
I72 Other aneurysm
0.000 0.861 0.139
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.862 0.137
I31.8 Other specified diseases of pericardium
0.000 0.863 0.137
I31.2 Haemopericardium, not elsewhere classified
0.000 0.863 0.137
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.863 0.137
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.863 0.137
I31.1 Chronic constrictive pericarditis
0.000 0.864 0.136
I73.9 Peripheral vascular disease, unspecified
0.000 0.865 0.135
I50.9 Heart failure, unspecified
0.000 0.865 0.135
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.865 0.135
I77.1 Stricture of artery
0.000 0.866 0.134
I09.8 Other specified rheumatic heart diseases
0.000 0.867 0.133
I09.2 Chronic rheumatic pericarditis
0.000 0.867 0.133
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.867 0.133
I09.0 Rheumatic myocarditis
0.000 0.867 0.133
I28 Other diseases of pulmonary vessels
0.000 0.870 0.130
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.871 0.129
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.873 0.127
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.874 0.126
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.875 0.125
I73.8 Other specified peripheral vascular diseases
0.000 0.876 0.124
I79.1 Aortitis in diseases classified elsewhere
0.000 0.876 0.124
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.876 0.124
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.876 0.124
I49.2 Junctional premature depolarisation
0.000 0.877 0.123
I74.8 Embolism and thrombosis of other arteries
0.000 0.877 0.123
I02 Rheumatic chorea
0.000 0.877 0.123
I01 Rheumatic fever with heart involvement
0.000 0.877 0.123
I77.3 Arterial fibromuscular dysplasia
0.000 0.877 0.122
I00 Rheumatic fever without mention of heart involvement
0.000 0.878 0.122
I31.0 Chronic adhesive pericarditis
0.000 0.880 0.120
I27 Other pulmonary heart diseases
0.000 0.880 0.120
I70.8 Atherosclerosis of other arteries
0.000 0.883 0.117
I05.2 Mitral stenosis with insufficiency
0.000 0.883 0.117
I31.9 Disease of pericardium, unspecified
0.000 0.884 0.116
I77.5 Necrosis of artery
0.000 0.885 0.115
I77.4 Coeliac artery compression syndrome
0.000 0.885 0.115
I70.0 Atherosclerosis of aorta
0.000 0.886 0.114
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.886 0.114
I77.6 Arteritis, unspecified
0.000 0.886 0.114
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.887 0.113
I05.0 Mitral stenosis
0.000 0.887 0.112
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.888 0.112
I72.8 Aneurysm of other specified arteries
0.000 0.889 0.111
I70.1 Atherosclerosis of renal artery
0.000 0.889 0.110
I46.1 Sudden cardiac death, so described
0.000 0.890 0.110
I70.9 Generalised and unspecified atherosclerosis
0.000 0.890 0.110
I49.1 Atrial premature depolarisation
0.000 0.892 0.108
I72.2 Aneurysm of renal artery
0.000 0.892 0.108
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.893 0.107
I77.2 Rupture of artery
0.000 0.893 0.106
I77.8 Other specified disorders of arteries and arterioles
0.000 0.895 0.105
I77.0 Arteriovenous fistula, acquired
0.000 0.895 0.104
I49.9 Cardiac arrhythmia, unspecified
0.000 0.897 0.103
I31.3 Pericardial effusion (noninflammatory)
0.000 0.898 0.102
I49.0 Ventricular fibrillation and flutter
0.000 0.898 0.101
I72.9 Aneurysm of unspecified site
0.000 0.899 0.101
I95 Hypotension
0.000 0.899 0.101
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.900 0.100
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.900 0.100
I99 Other and unspecified disorders of circulatory system
0.000 0.903 0.097
I49.3 Ventricular premature depolarisation
0.000 0.904 0.096
I72.0 Aneurysm of carotid artery
0.000 0.905 0.095
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.905 0.094
I28.1 Aneurysm of pulmonary artery
0.000 0.906 0.093
I35 Nonrheumatic aortic valve disorders
0.000 0.907 0.093
I28.8 Other specified diseases of pulmonary vessels
0.000 0.907 0.093
I27.0 Primary pulmonary hypertension
0.000 0.907 0.093
I72.1 Aneurysm of artery of upper extremity
0.000 0.908 0.092
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.909 0.091
I95.9 Hypotension, unspecified
0.000 0.909 0.091
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.912 0.088
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.912 0.088
I01.8 Other acute rheumatic heart disease
0.000 0.912 0.088
I01.2 Acute rheumatic myocarditis
0.000 0.912 0.088
I01.1 Acute rheumatic endocarditis
0.000 0.912 0.088
I01.0 Acute rheumatic pericarditis
0.000 0.912 0.088
I02.9 Rheumatic chorea without heart involvement
0.000 0.912 0.088
I02.0 Rheumatic chorea with heart involvement
0.000 0.912 0.088
I72.3 Aneurysm of iliac artery
0.000 0.913 0.087
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.913 0.087
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.913 0.086
I27.1 Kyphoscoliotic heart disease
0.000 0.914 0.086
I46.0 Cardiac arrest with successful resuscitation
0.000 0.914 0.086
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.916 0.084
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.916 0.083
I34.0 Mitral (valve) insufficiency
0.000 0.917 0.083
I49.5 Sick sinus syndrome
0.000 0.917 0.083
I34.1 Mitral (valve) prolapse
0.000 0.917 0.083
I27.9 Pulmonary heart disease, unspecified
0.000 0.917 0.083
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.918 0.082
I72.4 Aneurysm of artery of lower extremity
0.000 0.918 0.082
I73.0 Raynaud's syndrome
0.000 0.918 0.081
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.920 0.079
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.921 0.079
I74.5 Embolism and thrombosis of iliac artery
0.000 0.921 0.078
I95.0 Idiopathic hypotension
0.000 0.922 0.078
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.923 0.077
I27.2 Other secondary pulmonary hypertension
0.000 0.923 0.077
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.924 0.076
I27.8 Other specified pulmonary heart diseases
0.000 0.926 0.074
I95.8 Other hypotension
0.000 0.930 0.070
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.930 0.070
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.932 0.068
I97.1 Other functional disturbances following cardiac surgery
0.000 0.934 0.066
I49.8 Other specified cardiac arrhythmias
0.000 0.934 0.066
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.936 0.064
I95.2 Hypotension due to drugs
0.000 0.936 0.064
I97.0 Postcardiotomy syndrome
0.000 0.937 0.062
I35.0 Aortic (valve) stenosis
0.000 0.939 0.061
I10-I15 Hypertensive diseases
0.000 0.939 0.061
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.939 0.061
I35.1 Aortic (valve) insufficiency
0.000 0.943 0.057
I60-I69 Cerebrovascular diseases
0.000 0.946 0.054
I78 Diseases of capillaries
0.001 0.949 0.050
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.951 0.049
I35.8 Other aortic valve disorders
0.000 0.951 0.049
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.951 0.049
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.951 0.049
I98.0 Cardiovascular syphilis
0.000 0.951 0.049
I46.9 Cardiac arrest, unspecified
0.000 0.951 0.049
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.952 0.048
I13 Hypertensive heart and renal disease
0.000 0.953 0.047
I35.9 Aortic valve disorder, unspecified
0.000 0.953 0.047
I95.1 Orthostatic hypotension
0.000 0.953 0.047
Z51.4 Preparatory care for treatment, not elsewhere classified
0.000 0.954 0.046
I69 Sequelae of cerebrovascular disease
0.000 0.955 0.045
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.955 0.045
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.955 0.044
I65.2 Occlusion and stenosis of carotid artery
0.000 0.956 0.044
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.956 0.044
I15 Secondary hypertension
0.000 0.958 0.042
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.958 0.041
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.960 0.040
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.962 0.038
I69.3 Sequelae of cerebral infarction
0.000 0.962 0.038
I11 Hypertensive heart disease
0.000 0.963 0.037
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.963 0.037
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.963 0.036
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.964 0.036
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.964 0.036
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.965 0.035
I65.1 Occlusion and stenosis of basilar artery
0.000 0.965 0.034
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.965 0.034
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.966 0.034
I61 Intracerebral haemorrhage
0.000 0.966 0.034
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.966 0.034
C18 Malignant neoplasm of colon
0.000 0.966 0.034
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.966 0.033
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.966 0.033
I78.9 Disease of capillaries, unspecified
0.001 0.966 0.033
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.967 0.033
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.967 0.033
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.967 0.033
I68.0 Cerebral amyloid angiopathy
0.000 0.967 0.033
I15.1 Hypertension secondary to other renal disorders
0.000 0.968 0.032
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.968 0.032
C18.0 Caecum
0.000 0.968 0.032
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.968 0.031
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.969 0.031
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.969 0.031
C18.4 Transverse colon
0.000 0.969 0.031
I15.2 Hypertension secondary to endocrine disorders
0.000 0.969 0.030
I12 Hypertensive renal disease
0.000 0.970 0.030
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.970 0.030
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.970 0.030
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.970 0.030
I15.9 Seconday hypertension, unspecified
0.000 0.970 0.029
C18.1 Appendix
0.000 0.970 0.030
I78.8 Other diseases of capillaries
0.001 0.970 0.029
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.971 0.029
I15.8 Other secondary hypertension
0.000 0.971 0.029
I15.0 Renovascular hypertension
0.000 0.971 0.028
C18.9 Colon, unspecified
0.000 0.971 0.029
C18.2 Ascending colon
0.000 0.972 0.028
C18.7 Sigmoid colon
0.000 0.972 0.028
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.973 0.026
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.974 0.026
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.974 0.026
C18.8 Overlapping lesion of colon
0.000 0.974 0.026
C18.5 Splenic flexure
0.000 0.975 0.025
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.975 0.025
C18.3 Hepatic flexure
0.000 0.975 0.025
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.975 0.024
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.976 0.024
S09.9 Unspecified injury of head
0.024 0.976 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.976 0.024
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.977 0.023
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.977 0.023
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.978 0.021
C18.6 Descending colon
0.000 0.979 0.021
I12.9 Hypertensive renal disease without renal failure
0.000 0.979 0.021
I62 Other nontraumatic intracranial haemorrhage
0.001 0.979 0.020
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.979 0.020
H60.9 Otitis externa, unspecified
0.000 0.980 0.020
I67 Other cerebrovascular diseases
0.000 0.981 0.019
I61.8 Other intracerebral haemorrhage
0.000 0.981 0.018
I78.1 Naevus, nonneoplastic
0.001 0.981 0.018
H60 Otitis externa
0.000 0.982 0.018
I67.2 Cerebral atherosclerosis
0.000 0.982 0.018
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.983 0.017
I20-I25 Ischaemic heart diseases
0.000 0.983 0.017
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.983 0.016
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.984 0.016
H60.5 Acute otitis externa, non-infective
0.000 0.984 0.016
I62.1 Nontraumatic extradural haemorrhage
0.001 0.985 0.015
H60.3 Other infective otitis externa
0.000 0.985 0.015
H93.1 Tinnitus
0.000 0.985 0.015
H60.8 Other otitis externa
0.000 0.986 0.014
C15-C26 Malignant neoplasms of digestive organs
0.000 0.986 0.014
H93 Other disorders of ear, not elsewhere classified
0.000 0.986 0.014
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.986 0.014
H92.0 Otalgia
0.000 0.986 0.014
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.986 0.014
I67.5 Moyamoya disease
0.000 0.986 0.014
I67.3 Progressive vascular leukoencephalopathy
0.000 0.986 0.014
H92 Otalgia and effusion of ear
0.000 0.986 0.014
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.986 0.014
H60-H62 Diseases of external ear
0.000 0.986 0.014
C16 Malignant neoplasm of stomach
0.000 0.987 0.013
H60.4 Cholesteatoma of external ear
0.000 0.987 0.013
H60.2 Malignant otitis externa
0.000 0.987 0.013
I67.4 Hypertensive encephalopathy
0.000 0.987 0.013
C21 Malignant neoplasm of anus and anal canal
0.000 0.987 0.013
H90-H95 Other disorders of ear
0.000 0.987 0.013
H60.0 Abscess of external ear
0.000 0.987 0.013
H93.8 Other specified disorders of ear
0.000 0.987 0.013
S61.0 Open wound of finger(s) without damage to nail
0.012 0.988 0.000
H60.1 Cellulitis of external ear
0.000 0.988 0.012
H92.1 Otorrhoea
0.000 0.988 0.012
C21.0 Anus, unspecified
0.000 0.988 0.012
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.988 0.012
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.988 0.011
C16.8 Overlapping lesion of stomach
0.000 0.988 0.011
C16.4 Pylorus
0.000 0.989 0.011
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.989 0.011
I23 Certain current complications following acute myocardial infarction
0.000 0.989 0.011
C16.5 Lesser curvature of stomach, unspecified
0.000 0.989 0.011
N17.9 Acute renal failure, unspecified
0.000 0.989 0.011
H90.3 Sensorineural hearing loss, bilateral
0.000 0.989 0.011
H92.2 Otorrhagia
0.000 0.989 0.011
C23 Malignant neoplasm of gallbladder
0.000 0.989 0.011
I24 Other acute ischaemic heart diseases
0.000 0.989 0.011
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.989 0.011
I25.5 Ischaemic cardiomyopathy
0.000 0.989 0.011
H93.9 Disorder of ear, unspecified
0.000 0.989 0.011
Chapter VIII Diseases of the ear and mastoid process
0.000 0.989 0.011
I22 Subsequent myocardial infarction
0.000 0.989 0.010
H93.0 Degenerative and vascular disorders of ear
0.000 0.990 0.010
I25 Chronic ischaemic heart disease
0.000 0.990 0.010
H93.3 Disorders of acoustic nerve
0.000 0.990 0.010
H93.2 Other abnormal auditory perceptions
0.000 0.990 0.010
C17 Malignant neoplasm of small intestine
0.000 0.990 0.010
C16.2 Body of stomach
0.000 0.990 0.010
C16.1 Fundus of stomach
0.000 0.990 0.010
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.990 0.010
C16.3 Pyloric antrum
0.000 0.990 0.010
C16.0 Cardia
0.000 0.990 0.010
H61 Other disorders of external ear
0.000 0.990 0.010
I67.8 Other specified cerebrovascular diseases
0.000 0.990 0.010
N19 Unspecified renal failure
0.000 0.990 0.010
C21.1 Anal canal
0.000 0.990 0.010
I25.3 Aneurysm of heart
0.000 0.990 0.010
C26.0 Intestinal tract, part unspecified
0.000 0.990 0.010
C21.2 Cloacogenic zone
0.000 0.990 0.009
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.990 0.009
H90 Conductive and sensorineural hearing loss
0.000 0.990 0.009
I24.8 Other forms of acute ischaemic heart disease
0.000 0.991 0.009
I12.0 Hypertensive renal disease with renal failure
0.000 0.991 0.009
N17 Acute renal failure
0.000 0.991 0.009
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.991 0.009
S09 Other and unspecified injuries of head
0.009 0.991 0.000
C16.9 Stomach, unspecified
0.000 0.991 0.009
C20 Malignant neoplasm of rectum
0.000 0.991 0.009
I63 Cerebral infarction
0.000 0.991 0.009
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.991 0.009
C24.9 Biliary tract, unspecified
0.000 0.991 0.009
C16.6 Greater curvature of stomach, unspecified
0.000 0.991 0.008
I25.4 Coronary artery aneurysm
0.000 0.991 0.008
C24.1 Ampulla of Vater
0.000 0.992 0.008
N17-N19 Renal failure
0.000 0.992 0.008
C26.8 Overlapping lesion of digestive system
0.000 0.992 0.008
C26.1 Spleen
0.000 0.992 0.008
C17.2 Ileum
0.000 0.992 0.008
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.992 0.008
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.992 0.008
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.992 0.008
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.992 0.008
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.992 0.008
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.992 0.008
I24.1 Dressler's syndrome
0.000 0.992 0.008
H61.3 Acquired stenosis of external ear canal
0.000 0.992 0.008
H61.8 Other specified disorders of external ear
0.000 0.992 0.008
R02 Gangrene, not elsewhere classified
0.000 0.992 0.008
C17.9 Small intestine, unspecified
0.000 0.992 0.008
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.992 0.008
C24.8 Overlapping lesion of biliary tract
0.000 0.992 0.008
N17.0 Acute renal failure with tubular necrosis
0.000 0.992 0.008
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.992 0.008
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.992 0.008
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.992 0.008
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.992 0.008
C17.8 Overlapping lesion of small intestine
0.000 0.992 0.008
C17.3 Meckel's diverticulum
0.000 0.992 0.008
H61.1 Non-infective disorders of pinna
0.000 0.992 0.008
I23.8 Other current complications following acute myocardial infarction
0.000 0.992 0.007
I60 Subarachnoid haemorrhage
0.001 0.992 0.007
C26.9 Ill-defined sites within the digestive system
0.000 0.992 0.007
H61.0 Perichondritis of external ear
0.000 0.992 0.007
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.992 0.007
H83.0 Labyrinthitis
0.000 0.993 0.007
I22.8 Subsequent myocardial infarction of other sites
0.000 0.993 0.007
I25.6 Silent myocardial ischaemia
0.000 0.993 0.007
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.993 0.007
H94.8 Other specified disorders of ear in diseases classified elsewhere
0.000 0.993 0.007
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.993 0.007
H80-H83 Diseases of inner ear
0.000 0.993 0.007
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.993 0.006
I10 Essential (primary) hypertension
0.000 0.993 0.007
C17.1 Jejunum
0.000 0.993 0.007
H61.9 Disorder of external ear, unspecified
0.000 0.993 0.007
C24.0 Extrahepatic bile duct
0.000 0.993 0.007
N17.2 Acute renal failure with medullary necrosis
0.000 0.993 0.007
S09.2 Traumatic rupture of ear drum
0.007 0.993 0.000
H62.8 Other disorders of external ear in diseases classified elsewhere
0.000 0.993 0.007
H62.4 Otitis externa in other diseases classified elsewhere
0.000 0.993 0.007
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
H62.2 Otitis externa in mycoses
0.000 0.993 0.007
H62.1 Otitis externa in viral diseases classified elsewhere
0.000 0.993 0.007
S09.1 Injury of muscle and tendon of head
0.007 0.993 0.000
H83 Other diseases of inner ear
0.000 0.993 0.007
H90.5 Sensorineural hearing loss, unspecified
0.000 0.993 0.007
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.993 0.007
I25.1 Atherosclerotic heart disease
0.000 0.993 0.007
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.993 0.007
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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