TreeWAS – Variant ID: rs4823173

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70.3 Alcoholic cirrhosis of liver	1.000	0.000	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	1.000	0.000	0.000
K76 Other diseases of liver	1.000	0.000	0.000
K70 Alcoholic liver disease	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
K75.8 Other specified inflammatory liver diseases	1.000	0.000	0.000
K75 Other inflammatory liver diseases	1.000	0.000	0.000
K74.6 Other and unspecified cirrhosis of liver	1.000	0.000	0.000
K76.6 Portal hypertension	1.000	0.000	0.000
K74 Fibrosis and cirrhosis of liver	1.000	0.000	0.000
K76.9 Liver disease, unspecified	0.996	0.004	0.000
I85.9 Oesophageal varices without bleeding	0.995	0.005	0.000
K70.9 Alcoholic liver disease, unspecified	0.983	0.017	0.000
K70.0 Alcoholic fatty liver	0.964	0.036	0.000
K75.4 Autoimmune hepatitis	0.946	0.054	0.000
K72 Hepatic failure, not elsewhere classified	0.945	0.055	0.000
K70.1 Alcoholic hepatitis	0.937	0.063	0.000
K72.9 Hepatic failure, unspecified	0.903	0.097	0.000
K80 Cholelithiasis	0.000	0.107	0.893
K70.4 Alcoholic hepatic failure	0.891	0.109	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.120	0.880
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.127	0.873
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.140	0.860
I85 Oesophageal varices	0.836	0.164	0.000
K76.7 Hepatorenal syndrome	0.835	0.165	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.165	0.835
K74.0 Hepatic fibrosis	0.819	0.181	0.000
K73 Chronic hepatitis, not elsewhere classified	0.810	0.190	0.000
K71 Toxic liver disease	0.809	0.191	0.000
I85.0 Oesophageal varices with bleeding	0.783	0.217	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.773	0.227	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.761	0.239	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.254	0.746
K76.5 Hepatic veno-occlusive disease	0.717	0.283	0.000
K76.4 Peliosis hepatis	0.717	0.283	0.000
K76.3 Infarction of liver	0.717	0.283	0.000
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283	0.000
K76.1 Chronic passive congestion of liver	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K75.2 Nonspecific reactive hepatitis	0.717	0.283	0.000
K75.1 Phlebitis of portal vein	0.717	0.283	0.000
K74.4 Secondary biliary cirrhosis	0.717	0.283	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.717	0.283	0.000
K74.1 Hepatic sclerosis	0.717	0.283	0.000
K73.9 Chronic hepatitis, unspecified	0.703	0.297	0.000
K72.1 Chronic hepatic failure	0.698	0.302	0.000
K80.8 Other cholelithiasis	0.000	0.311	0.689
K82 Other diseases of gallbladder	0.000	0.315	0.685
K72.0 Acute and subacute hepatic failure	0.678	0.322	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.672	0.327	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.669	0.331	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.351	0.649
K82.8 Other specified diseases of gallbladder	0.000	0.355	0.645
K74.5 Biliary cirrhosis, unspecified	0.645	0.355	0.000
K81 Cholecystitis	0.000	0.356	0.644
K80.3 Calculus of bile duct with cholangitis	0.000	0.360	0.640
K85 Acute pancreatitis	0.000	0.372	0.628
K75.9 Inflammatory liver disease, unspecified	0.624	0.376	0.000
K75.0 Abscess of liver	0.591	0.409	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.581	0.419	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.581	0.419	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.581	0.419	0.000
K71.9 Toxic liver disease, unspecified	0.580	0.420	0.000
K71.8 Toxic liver disease with other disorders of liver	0.580	0.420	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.580	0.420	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.580	0.420	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.580	0.420	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.580	0.420	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.580	0.420	0.000
K71.2 Toxic liver disease with acute hepatitis	0.580	0.420	0.000
K71.0 Toxic liver disease with cholestasis	0.580	0.420	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.569	0.431	0.000
K81.0 Acute cholecystitis	0.000	0.437	0.563
K74.3 Primary biliary cirrhosis	0.556	0.444	0.000
K82.2 Perforation of gallbladder	0.000	0.445	0.555
K86 Other diseases of pancreas	0.000	0.461	0.539
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.465	0.535
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.523	0.477	0.000
K85.2 Alcohol-induced acute pancreatitis	0.000	0.479	0.521
K73.2 Chronic active hepatitis, not elsewhere classified	0.519	0.480	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.514	0.486	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
K82.3 Fistula of gallbladder	0.000	0.494	0.506
K81.9 Cholecystitis, unspecified	0.000	0.500	0.500
K81.1 Chronic cholecystitis	0.000	0.504	0.496
K85.9 Acute pancreatitis, unspecified	0.000	0.505	0.495
K82.0 Obstruction of gallbladder	0.000	0.505	0.494
K82.1 Hydrops of gallbladder	0.000	0.521	0.479
K86.2 Cyst of pancreas	0.000	0.524	0.476
K85.8 Other acute pancreatitis	0.000	0.529	0.471
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.541	0.459
K85.3 Drug-induced acute pancreatitis	0.000	0.550	0.450
K85.0 Idiopathic acute pancreatitis	0.000	0.550	0.450
K82.9 Disease of gallbladder, unspecified	0.000	0.558	0.442
K86.9 Disease of pancreas, unspecified	0.000	0.562	0.438
K86.8 Other specified diseases of pancreas	0.000	0.571	0.429
K85.1 Biliary acute pancreatitis	0.000	0.583	0.417
K82.4 Cholesterolosis of gallbladder	0.000	0.584	0.416
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.408	0.592	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.408	0.592	0.000
I98.0 Cardiovascular syphilis	0.408	0.592	0.000
K86.3 Pseudocyst of pancreas	0.000	0.593	0.407
K81.8 Other cholecystitis	0.000	0.608	0.392
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.616	0.384
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.616	0.384
K83 Other diseases of biliary tract	0.000	0.640	0.360
I95-I99 Other and unspecified disorders of the circulatory system	0.326	0.674	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.324	0.676	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.705	0.295
K83.9 Disease of biliary tract, unspecified	0.000	0.712	0.288
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.285	0.714	0.000
I88 Nonspecific lymphadenitis	0.279	0.721	0.000
I81 Portal vein thrombosis	0.272	0.728	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.266	0.734	0.000
K83.5 Biliary cyst	0.000	0.742	0.258
K83.4 Spasm of sphincter of Oddi	0.000	0.742	0.258
K83.2 Perforation of bile duct	0.000	0.742	0.258
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.252	0.748	0.000
I87 Other disorders of veins	0.250	0.750	0.000
I86 Varicose veins of other sites	0.248	0.752	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.247	0.753	0.000
K83.3 Fistula of bile duct	0.000	0.755	0.244
I89.1 Lymphangitis	0.243	0.757	0.000
I99 Other and unspecified disorders of circulatory system	0.231	0.769	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.227	0.773	0.000
R18 Ascites	0.222	0.778	0.000
I86.4 Gastric varices	0.222	0.778	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.783	0.217
I97.2 Postmastectomy lymphoedema syndrome	0.205	0.795	0.000
I88.8 Other nonspecific lymphadenitis	0.200	0.800	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.200	0.800	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.200	0.800	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.198	0.802	0.000
I95 Hypotension	0.197	0.803	0.000
I82 Other venous embolism and thrombosis	0.194	0.806	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.191	0.809	0.000
I97.0 Postcardiotomy syndrome	0.191	0.809	0.000
I89.0 Lymphoedema, not elsewhere classified	0.187	0.813	0.000
I86.8 Varicose veins of other specified sites	0.185	0.815	0.000
I87.1 Compression of vein	0.183	0.817	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.181	0.819	0.000
I83 Varicose veins of lower extremities	0.180	0.820	0.000
I87.9 Disorder of vein, unspecified	0.179	0.820	0.000
I87.0 Postphlebitic syndrome	0.179	0.820	0.000
K76.8 Other specified diseases of liver	0.178	0.822	0.000
I86.3 Vulval varices	0.178	0.822	0.000
I86.0 Sublingual varices	0.178	0.822	0.000
I87.8 Other specified disorders of veins	0.175	0.825	0.000
I86.2 Pelvic varices	0.172	0.828	0.000
I97.1 Other functional disturbances following cardiac surgery	0.164	0.836	0.000
K83.0 Cholangitis	0.000	0.837	0.163
I82.2 Embolism and thrombosis of vena cava	0.162	0.838	0.000
I95.1 Orthostatic hypotension	0.160	0.840	0.000
I95.0 Idiopathic hypotension	0.157	0.843	0.000
I95.8 Other hypotension	0.152	0.848	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.152	0.848	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.142	0.858	0.000
Chapter IX Diseases of the circulatory system	0.141	0.859	0.000
I82.3 Embolism and thrombosis of renal vein	0.139	0.860	0.000
I82.1 Thrombophlebitis migrans	0.139	0.860	0.000
I82.0 Budd-Chiari syndrome	0.139	0.860	0.000
K86.1 Other chronic pancreatitis	0.000	0.866	0.133
I95.2 Hypotension due to drugs	0.128	0.872	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.111	0.889	0.000
I82.8 Embolism and thrombosis of other specified veins	0.104	0.896	0.000
I00-I02 Acute rheumatic fever	0.101	0.899	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.098	0.902	0.000
I86.1 Scrotal varices	0.093	0.906	0.000
I05-I09 Chronic rheumatic heart diseases	0.083	0.917	0.000
K83.1 Obstruction of bile duct	0.000	0.922	0.078
I05 Rheumatic mitral valve diseases	0.078	0.922	0.000
I02 Rheumatic chorea	0.072	0.927	0.000
I01 Rheumatic fever with heart involvement	0.072	0.927	0.000
I00 Rheumatic fever without mention of heart involvement	0.072	0.927	0.000
I05.1 Rheumatic mitral insufficiency	0.069	0.931	0.000
I05.9 Mitral valve disease, unspecified	0.068	0.932	0.000
I06 Rheumatic aortic valve diseases	0.060	0.940	0.000
C22.0 Liver cell carcinoma	0.058	0.942	0.000
I05.0 Mitral stenosis	0.058	0.942	0.000
I05.8 Other mitral valve diseases	0.056	0.944	0.000
I09 Other rheumatic heart diseases	0.055	0.945	0.000
I10-I15 Hypertensive diseases	0.053	0.947	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.052	0.948	0.000
I01.8 Other acute rheumatic heart disease	0.052	0.948	0.000
I01.2 Acute rheumatic myocarditis	0.052	0.948	0.000
I01.1 Acute rheumatic endocarditis	0.052	0.948	0.000
I01.0 Acute rheumatic pericarditis	0.052	0.948	0.000
I02.9 Rheumatic chorea without heart involvement	0.052	0.948	0.000
I02.0 Rheumatic chorea with heart involvement	0.052	0.948	0.000
I05.2 Mitral stenosis with insufficiency	0.051	0.949	0.000
I11 Hypertensive heart disease	0.047	0.953	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.045	0.955	0.000
I07 Rheumatic tricuspid valve diseases	0.044	0.956	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.043	0.957	0.000
I06.8 Other rheumatic aortic valve diseases	0.043	0.957	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.043	0.957	0.000
I06.1 Rheumatic aortic insufficiency	0.043	0.957	0.000
I06.0 Rheumatic aortic stenosis	0.043	0.957	0.000
C22.9 Liver, unspecified	0.041	0.959	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.035	0.960	0.005
I09.8 Other specified rheumatic heart diseases	0.039	0.960	0.000
I09.2 Chronic rheumatic pericarditis	0.039	0.960	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.039	0.960	0.000
I09.0 Rheumatic myocarditis	0.039	0.960	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.039	0.960	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.039	0.961	0.000
I13 Hypertensive heart and renal disease	0.038	0.961	0.000
C22.1 Intrahepatic bile duct carcinoma	0.038	0.962	0.000
I15 Secondary hypertension	0.038	0.962	0.000
H65-H75 Diseases of middle ear and mastoid	0.035	0.965	0.000
I09.9 Rheumatic heart disease, unspecified	0.034	0.966	0.000
H74 Other disorders of middle ear and mastoid	0.034	0.966	0.000
C22.7 Other specified carcinomas of liver	0.033	0.967	0.000
C22.4 Other sarcomas of liver	0.033	0.967	0.000
C22.3 Angiosarcoma of liver	0.033	0.967	0.000
C22.2 Hepatoblastoma	0.033	0.967	0.000
I07.9 Tricuspid valve disease, unspecified	0.032	0.968	0.000
I07.8 Other tricuspid valve diseases	0.032	0.968	0.000
I07.2 Tricuspid stenosis with insufficiency	0.032	0.968	0.000
I07.0 Tricuspid stenosis	0.032	0.968	0.000
H74.0 Tympanosclerosis	0.031	0.969	0.000
H60 Otitis externa	0.030	0.970	0.000
Chapter VIII Diseases of the ear and mastoid process	0.030	0.970	0.000
H66 Suppurative and unspecified otitis media	0.029	0.971	0.000
H73 Other disorders of tympanic membrane	0.029	0.971	0.000
H60.9 Otitis externa, unspecified	0.029	0.971	0.000
H65 Nonsuppurative otitis media	0.029	0.971	0.000
I15.1 Hypertension secondary to other renal disorders	0.029	0.971	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.028	0.972	0.000
H60-H62 Diseases of external ear	0.028	0.972	0.000
H74.4 Polyp of middle ear	0.028	0.972	0.000
I28 Other diseases of pulmonary vessels	0.024	0.972	0.004
H74.2 Discontinuity and dislocation of ear ossicles	0.028	0.972	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.028	0.972	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.028	0.972	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.028	0.972	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.028	0.972	0.000
I15.8 Other secondary hypertension	0.028	0.972	0.000
I15.2 Hypertension secondary to endocrine disorders	0.028	0.972	0.000
I15.0 Renovascular hypertension	0.028	0.972	0.000
H90-H95 Other disorders of ear	0.028	0.972	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.027	0.973	0.000
H72 Perforation of tympanic membrane	0.027	0.973	0.000
H60.1 Cellulitis of external ear	0.027	0.973	0.000
H71 Cholesteatoma of middle ear	0.027	0.973	0.000
I15.9 Seconday hypertension, unspecified	0.026	0.974	0.000
H73.8 Other specified disorders of tympanic membrane	0.026	0.974	0.000
H66.0 Acute suppurative otitis media	0.026	0.974	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.025	0.975	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.025	0.975	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.025	0.975	0.000
H68 Eustachian salpingitis and obstruction	0.025	0.975	0.000
H67 Otitis media in diseases classified elsewhere	0.025	0.975	0.000
H92 Otalgia and effusion of ear	0.025	0.975	0.000
I80 Phlebitis and thrombophlebitis	0.025	0.975	0.000
H60.5 Acute otitis externa, non-infective	0.025	0.975	0.000
H65.1 Other acute nonsuppurative otitis media	0.025	0.975	0.000
H69 Other disorders of Eustachian tube	0.025	0.975	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.025	0.975	0.000
H70 Mastoiditis and related conditions	0.024	0.976	0.000
H66.3 Other chronic suppurative otitis media	0.023	0.977	0.000
H95.1 Other disorders following mastoidectomy	0.023	0.977	0.000
H65.2 Chronic serous otitis media	0.023	0.977	0.000
H65.4 Other chronic nonsuppurative otitis media	0.022	0.978	0.000
H60.4 Cholesteatoma of external ear	0.022	0.978	0.000
H60.3 Other infective otitis externa	0.022	0.978	0.000
H74.1 Adhesive middle ear disease	0.022	0.978	0.000
H90 Conductive and sensorineural hearing loss	0.022	0.978	0.000
H60.2 Malignant otitis externa	0.022	0.978	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.022	0.978	0.000
H60.0 Abscess of external ear	0.021	0.978	0.000
H72.8 Other perforations of tympanic membrane	0.021	0.979	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.021	0.979	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.979	0.021
H72.0 Central perforation of tympanic membrane	0.021	0.979	0.000
H65.0 Acute serous otitis media	0.021	0.979	0.000
H73.1 Chronic myringitis	0.021	0.979	0.000
H73.0 Acute myringitis	0.021	0.979	0.000
H66.4 Suppurative otitis media, unspecified	0.021	0.979	0.000
H92.0 Otalgia	0.021	0.979	0.000
H60.8 Other otitis externa	0.021	0.979	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.020	0.979	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.018	0.979	0.003
I28.1 Aneurysm of pulmonary artery	0.018	0.979	0.003
I28.0 Arteriovenous fistula of pulmonary vessels	0.018	0.979	0.003
H92.2 Otorrhagia	0.020	0.980	0.000
I26 Pulmonary embolism	0.011	0.980	0.010
H94 Other disorders of ear in diseases classified elsewhere	0.020	0.980	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.020	0.980	0.000
H72.1 Attic perforation of tympanic membrane	0.020	0.980	0.000
I28.8 Other specified diseases of pulmonary vessels	0.017	0.980	0.003
H92.1 Otorrhoea	0.020	0.980	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.019	0.981	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.019	0.981	0.000
H72.2 Other marginal perforations of tympanic membrane	0.019	0.981	0.000
H69.9 Eustachian tube disorder, unspecified	0.019	0.981	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.018	0.982	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.018	0.982	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.018	0.982	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.018	0.982	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.018	0.982	0.000
H68.1 Obstruction of Eustachian tube	0.018	0.982	0.000
H68.0 Eustachian salpingitis	0.018	0.982	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.018	0.982	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.018	0.982	0.000
H69.0 Patulous Eustachian tube	0.018	0.982	0.000
H70.8 Other mastoiditis and related conditions	0.017	0.982	0.000
H70.2 Petrositis	0.017	0.982	0.000
H70.1 Chronic mastoiditis	0.017	0.982	0.000
H70.0 Acute mastoiditis	0.017	0.982	0.000
H90.5 Sensorineural hearing loss, unspecified	0.017	0.983	0.000
H90.0 Conductive hearing loss, bilateral	0.017	0.983	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.017	0.983	0.000
H93 Other disorders of ear, not elsewhere classified	0.017	0.983	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.017	0.983	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.017	0.983	0.000
H70.9 Mastoiditis, unspecified	0.016	0.983	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.016	0.984	0.000
H69.8 Other specified disorders of Eustachian tube	0.016	0.984	0.000
I07.1 Tricuspid insufficiency	0.016	0.984	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.016	0.984	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.016	0.984	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.016	0.984	0.000
H80-H83 Diseases of inner ear	0.016	0.984	0.000
I62 Other nontraumatic intracranial haemorrhage	0.016	0.984	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.015	0.985	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.015	0.985	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.015	0.985	0.000
H62.2 Otitis externa in mycoses	0.015	0.985	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.015	0.985	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.015	0.985	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.014	0.985	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.014	0.985	0.000
I12 Hypertensive renal disease	0.014	0.985	0.000
N43.3 Hydrocele, unspecified	0.014	0.986	0.000
H91 Other hearing loss	0.014	0.986	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.014	0.986	0.000
H90.2 Conductive hearing loss, unspecified	0.014	0.986	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.006	0.986	0.008
I60-I69 Cerebrovascular diseases	0.014	0.986	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.013	0.987	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.013	0.987	0.000
H93.9 Disorder of ear, unspecified	0.013	0.987	0.000
H93.3 Disorders of acoustic nerve	0.013	0.987	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.987	0.013
H93.8 Other specified disorders of ear	0.013	0.987	0.000
H66.9 Otitis media, unspecified	0.013	0.987	0.000
H93.2 Other abnormal auditory perceptions	0.012	0.988	0.000
H93.0 Degenerative and vascular disorders of ear	0.012	0.988	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.012	0.988	0.000
H83 Other diseases of inner ear	0.012	0.988	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.012	0.988	0.000
H91.8 Other specified hearing loss	0.012	0.988	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.011	0.988	0.000
I62.1 Nontraumatic extradural haemorrhage	0.011	0.989	0.000
I78 Diseases of capillaries	0.011	0.989	0.000
I27 Other pulmonary heart diseases	0.006	0.989	0.004
H90.3 Sensorineural hearing loss, bilateral	0.011	0.989	0.000
H91.2 Sudden idiopathic hearing loss	0.010	0.990	0.000
H91.0 Ototoxic hearing loss	0.010	0.990	0.000
I78.8 Other diseases of capillaries	0.010	0.990	0.000
I78.1 Naevus, nonneoplastic	0.010	0.990	0.000
H91.1 Presbycusis	0.010	0.990	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.010	0.990	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.010	0.990	0.000
H83.3 Noise effects on inner ear	0.010	0.990	0.000
H80 Otosclerosis	0.010	0.990	0.000
I61 Intracerebral haemorrhage	0.010	0.990	0.000
H61 Other disorders of external ear	0.010	0.990	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.990	0.010
H83.9 Disease of inner ear, unspecified	0.009	0.991	0.000
H83.8 Other specified diseases of inner ear	0.009	0.991	0.000
H83.2 Labyrinthine dysfunction	0.009	0.991	0.000
H83.1 Labyrinthine fistula	0.009	0.991	0.000
H91.3 Deaf mutism, not elsewhere classified	0.009	0.991	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.009	0.991	0.000
H83.0 Labyrinthitis	0.009	0.991	0.000
I72 Other aneurysm	0.009	0.991	0.000
I08 Multiple valve diseases	0.008	0.991	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.008	0.991	0.000
I70 Atherosclerosis	0.008	0.992	0.000
I78.9 Disease of capillaries, unspecified	0.008	0.992	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.008	0.992	0.000
I27.1 Kyphoscoliotic heart disease	0.005	0.992	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.008	0.992	0.000
J33.0 Polyp of nasal cavity	0.000	0.992	0.008
H61.8 Other specified disorders of external ear	0.008	0.992	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.008	0.992	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.008	0.992	0.000
I27.8 Other specified pulmonary heart diseases	0.005	0.992	0.003
H61.1 Non-infective disorders of pinna	0.008	0.992	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.008	0.992	0.000
W08.0 Home	0.008	0.992	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.007	0.992	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.007	0.992	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.007	0.992	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.007	0.992	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.007	0.992	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.007	0.992	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.007	0.992	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.007	0.992	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.007	0.992	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I68.0 Cerebral amyloid angiopathy	0.007	0.992	0.000
E83.1 Disorders of iron metabolism	0.008	0.992	0.000
H80.8 Other otosclerosis	0.007	0.992	0.000
H80.2 Cochlear otosclerosis	0.007	0.992	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.007	0.992	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.007	0.992	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.007	0.993	0.000
I61.8 Other intracerebral haemorrhage	0.007	0.993	0.000
I72.2 Aneurysm of renal artery	0.007	0.993	0.000
K46 Unspecified abdominal hernia	0.007	0.993	0.000
I70.0 Atherosclerosis of aorta	0.007	0.993	0.000
I27.9 Pulmonary heart disease, unspecified	0.003	0.993	0.004
I72.0 Aneurysm of carotid artery	0.007	0.993	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.007	0.993	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.007	0.993	0.000
I08.8 Other multiple valve diseases	0.006	0.993	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.007	0.993	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.993	0.000
I72.9 Aneurysm of unspecified site	0.006	0.993	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.006	0.993	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.006	0.993	0.000
I72.4 Aneurysm of artery of lower extremity	0.006	0.993	0.000
I72.1 Aneurysm of artery of upper extremity	0.006	0.993	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.006	0.994	0.000
I79.1 Aortitis in diseases classified elsewhere	0.006	0.994	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.006	0.994	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.006	0.994	0.000
H61.3 Acquired stenosis of external ear canal	0.006	0.994	0.000
I70.9 Generalised and unspecified atherosclerosis	0.006	0.994	0.000
I70.8 Atherosclerosis of other arteries	0.006	0.994	0.000
N02.9 Unspecified	0.006	0.994	0.000
H81 Disorders of vestibular function	0.006	0.994	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.000	0.994	0.006
I12.9 Hypertensive renal disease without renal failure	0.006	0.994	0.000
I70.1 Atherosclerosis of renal artery	0.006	0.994	0.000
I72.3 Aneurysm of iliac artery	0.006	0.994	0.000
N94.1 Dyspareunia	0.000	0.994	0.006
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.006	0.994	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.006	0.994	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.006	0.994	0.000
I65.1 Occlusion and stenosis of basilar artery	0.006	0.994	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.006	0.994	0.000
H80.9 Otosclerosis, unspecified	0.006	0.994	0.000
L60.0 Ingrowing nail	0.000	0.994	0.006
N94.3 Premenstrual tension syndrome	0.000	0.994	0.006
H93.1 Tinnitus	0.006	0.994	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.006	0.994	0.000
N02 Recurrent and persistent haematuria	0.006	0.994	0.000
I60 Subarachnoid haemorrhage	0.006	0.994	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.006	0.994	0.000
I27.2 Other secondary pulmonary hypertension	0.003	0.994	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.994	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.000	0.994	0.006
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.994	0.000
H61.9 Disorder of external ear, unspecified	0.005	0.994	0.000
Z01.6 Radiological examination, not elsewhere classified	0.006	0.994	0.000
H81.0 Meniere's disease	0.005	0.994	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.005	0.995	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.005	0.995	0.000
N05 Unspecified nephritic syndrome	0.005	0.995	0.000
I27.0 Primary pulmonary hypertension	0.001	0.995	0.004
I70.01 Atherosclerosis of aorta (with gangrene)	0.005	0.995	0.000
N05.9 Unspecified	0.005	0.995	0.000
N00-N08 Glomerular diseases	0.005	0.995	0.000
H61.2 Impacted cerumen	0.005	0.995	0.000
H81.3 Other peripheral vertigo	0.005	0.995	0.000
I72.8 Aneurysm of other specified arteries	0.005	0.995	0.000
I20-I25 Ischaemic heart diseases	0.005	0.995	0.000
N43 Hydrocele and spermatocele	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.005	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.995	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.005	0.995	0.000
H81.4 Vertigo of central origin	0.004	0.995	0.000
N94.2 Vaginismus	0.000	0.995	0.005
H61.0 Perichondritis of external ear	0.005	0.995	0.000
N02.8 Other	0.005	0.995	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.995	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
H81.8 Other disorders of vestibular function	0.004	0.995	0.000
N02.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.995	0.005
L60 Nail disorders	0.000	0.995	0.005
N94.0 Mittelschmerz	0.000	0.995	0.004
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.995	0.000
N05.2 Diffuse membranous glomerulonephritis	0.004	0.995	0.000
L60.8 Other nail disorders	0.000	0.995	0.004
I71 Aortic aneurysm and dissection	0.004	0.995	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.004	0.996	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.004	0.996	0.000
N02.6 Dense deposit disease	0.004	0.996	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations