TreeWAS – Variant ID: rs4878497

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	0.324	0.676	0.000
E10.4 With neurological complications	0.319	0.681	0.000
E10.3 With ophthalmic complications	0.314	0.686	0.000
E14 Unspecified diabetes mellitus	0.314	0.686	0.000
E10-E14 Diabetes mellitus	0.311	0.689	0.000
E10.5 With peripheral circulatory complications	0.301	0.699	0.000
E14.3 With ophthalmic complications	0.300	0.700	0.000
E14.9 Without complications	0.292	0.708	0.000
E10.8 With unspecified complications	0.263	0.737	0.000
E14.6 With other specified complications	0.254	0.746	0.000
E14.2 Withrenal complications	0.250	0.750	0.000
E10.1 With ketoacidosis	0.243	0.757	0.000
E14.0 With coma	0.243	0.757	0.000
E11 Non-insulin-dependent diabetes mellitus	0.240	0.760	0.000
E14.5 With peripheral circulatory complications	0.239	0.760	0.000
E14.1 With ketoacidosis	0.236	0.764	0.000
E10.2 With renal complications	0.232	0.768	0.000
E14.7 With multiple complications	0.225	0.775	0.000
E11.2 With renal complications	0.224	0.776	0.000
E10.0 With coma	0.223	0.776	0.000
E12 Malnutrition-related diabetes mellitus	0.223	0.777	0.000
E14.4 With neurological complications	0.220	0.780	0.000
E10.7 With multiple complications	0.208	0.792	0.000
E11.0 With coma	0.194	0.806	0.000
E11.8 With unspecified complications	0.194	0.806	0.000
E14.8 With unspecified complications	0.188	0.812	0.000
E13 Other specified diabetes mellitus	0.184	0.815	0.000
E11.9 Without complications	0.184	0.816	0.000
E11.1 With ketoacidosis	0.180	0.820	0.000
E10.6 With other specified complications	0.179	0.821	0.000
E11.7 With multiple complications	0.172	0.828	0.000
E12.9 Without complications	0.160	0.840	0.000
E12.8 With unspecified complications	0.160	0.840	0.000
E12.7 With multiple complications	0.160	0.840	0.000
E12.6 With other specified complications	0.160	0.840	0.000
E12.5 With peripheral circulatory complications	0.160	0.840	0.000
E12.4 With neurological complications	0.160	0.840	0.000
E12.3 With ophthalmic complications	0.160	0.840	0.000
E12.2 With renal complications	0.160	0.840	0.000
E12.1 With ketoacidosis	0.160	0.840	0.000
E12.0 With coma	0.160	0.840	0.000
E11.3 With ophthalmic complications	0.147	0.853	0.000
E11.6 With other specified complications	0.147	0.853	0.000
E13.3 With ophthalmic complications	0.134	0.865	0.000
E13.8 With unspecified complications	0.132	0.867	0.000
E13.7 With multiple complications	0.132	0.867	0.000
E13.6 With other specified complications	0.132	0.867	0.000
E13.5 With peripheral circulatory complications	0.132	0.867	0.000
E13.4 With neurological complications	0.132	0.867	0.000
E13.2 With renal complications	0.132	0.867	0.000
E13.1 With ketoacidosis	0.132	0.867	0.000
E13.0 With coma	0.132	0.867	0.000
E11.4 With neurological complications	0.098	0.902	0.000
E13.9 Without complications	0.090	0.910	0.000
E10.9 Without complications	0.082	0.918	0.000
E11.5 With peripheral circulatory complications	0.072	0.928	0.000
Z99.1 Dependence on respirator	0.057	0.943	0.000
L40.5 Arthropathic psoriasis	0.051	0.949	0.000
L40 Psoriasis	0.051	0.949	0.000
L40.9 Psoriasis, unspecified	0.048	0.952	0.000
L40.0 Psoriasis vulgaris	0.047	0.953	0.000
L40.8 Other psoriasis	0.043	0.957	0.000
L40.1 Generalised pustular psoriasis	0.040	0.960	0.000
L40.4 Guttate psoriasis	0.037	0.963	0.000
L40.3 Pustulosis palmaris et plantaris	0.037	0.963	0.000
L40.2 Acrodermatitis continua	0.037	0.963	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.017	0.983	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.983	0.017
I86.4 Gastric varices	0.016	0.984	0.000
Z99.8 Dependence on other enabling machines and devices	0.016	0.984	0.000
N75 Diseases of Bartholin's gland	0.000	0.987	0.013
Z99.9 Dependence on unspecified enabling machine and device	0.012	0.987	0.000
Z99.4 Dependence on artificial heart	0.012	0.987	0.000
Z99.0 Dependence on aspirator	0.012	0.987	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.988	0.012
L40-L45 Papulosquamous disorders	0.010	0.990	0.000
N75.8 Other diseases of Bartholin's gland	0.000	0.990	0.010
M54.39 Sciatica (Site unspecified)	0.010	0.990	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.991	0.009
Z99.3 Dependence on wheelchair	0.009	0.991	0.000
I86 Varicose veins of other sites	0.008	0.992	0.000
L41 Parapsoriasis	0.007	0.992	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.007	0.992	0.000
L44 Other papulosquamous disorders	0.007	0.993	0.000
D48.1 Connective and other soft tissue	0.000	0.993	0.007
L42 Pityriasis rosea	0.007	0.993	0.000
I86.1 Scrotal varices	0.007	0.993	0.000
S42.20 Fracture of upper end of humerus (closed)	0.007	0.993	0.000
N19 Unspecified renal failure	0.006	0.994	0.000
Z50.8 Care involving use of rehabilitation procedures	0.006	0.994	0.000
I86.3 Vulval varices	0.006	0.994	0.000
I86.2 Pelvic varices	0.006	0.994	0.000
I86.0 Sublingual varices	0.006	0.994	0.000
L41.9 Parapsoriasis, unspecified	0.005	0.994	0.000
L41.8 Other parapsoriasis	0.005	0.994	0.000
L41.5 Retiform parapsoriasis	0.005	0.994	0.000
L41.4 Large plaque parapsoriasis	0.005	0.994	0.000
L41.3 Small plaque parapsoriasis	0.005	0.994	0.000
L41.2 Lymphomatoid papulosis	0.005	0.994	0.000
L41.1 Pityriasis lichenoides chronica	0.005	0.994	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.005	0.994	0.000
L44.9 Papulosquamous disorder, unspecified	0.005	0.995	0.000
L44.8 Other specified papulosquamous disorders	0.005	0.995	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.005	0.995	0.000
L44.3 Lichen ruber moniliformis	0.005	0.995	0.000
L44.2 Lichen striatus	0.005	0.995	0.000
L44.1 Lichen nitidus	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.995	0.005
I86.8 Varicose veins of other specified sites	0.005	0.995	0.000
L44.0 Pityriasis rubra pilaris	0.005	0.995	0.000
L43 Lichen planus	0.005	0.995	0.000
Z99.2 Dependence on renal dialysis	0.005	0.995	0.000
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
J69.0 Pneumonitis due to food and vomit	0.004	0.996	0.000
S42.2 Fracture of upper end of humerus	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
G60.0 Hereditary motor and sensory neuropathy	0.004	0.996	0.000
D04.7 Skin of lower limb, including hip	0.004	0.996	0.000
S13.4 Sprain and strain of cervical spine	0.004	0.996	0.000
M54.3 Sciatica	0.004	0.996	0.000
S42.21 Fracture of upper end of humerus (open)	0.004	0.996	0.000
H49.2 Sixth [abducent] nerve palsy	0.004	0.996	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.004	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.004	0.996	0.000
L43.3 Subacute (active) lichen planus	0.003	0.996	0.000
L43.2 Lichenoid drug reaction	0.003	0.996	0.000
L43.1 Bullous lichen planus	0.003	0.996	0.000
L43.0 Hypertrophic lichen planus	0.003	0.996	0.000
D89.1 Cryoglobulinaemia	0.000	0.996	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.996	0.000
D04 Carcinoma in situ of skin	0.004	0.996	0.000
L43.8 Other lichen planus	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.003	0.997	0.000
D04.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.997	0.003
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.000	0.997	0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
D04.5 Skin of trunk	0.003	0.997	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.997	0.003
M54.35 Sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.34 Sciatica-Thoracic	0.003	0.997	0.000
M54.33 Sciatica-Cervicothoracic	0.003	0.997	0.000
M54.32 Sciatica-Cervical	0.003	0.997	0.000
M54.31 Sciatica-Occipit-atl-axl	0.003	0.997	0.000
J15.2 Pneumonia due to staphylococcus	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
K25.4 Chronic or unspecified with haemorrhage	0.000	0.997	0.003
Z60.2 Living alone	0.003	0.997	0.000
D04.4 Skin of scalp and neck	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
Z92.0 Personal history of contraception	0.000	0.997	0.003
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
D24 Benign neoplasm of breast	0.000	0.997	0.003
D04.8 Skin of other sites	0.003	0.997	0.000
D04.0 Skin of lip	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.003
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.997	0.003
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.000	0.997	0.003
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.003
H52.0 Hypermetropia	0.003	0.997	0.000
D84 Other immunodeficiencies	0.000	0.997	0.003
M89.5 Osteolysis	0.002	0.997	0.000
E65 Localised adiposity	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M94.2 Chondromalacia	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.000	0.998	0.002
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
D84.1 Defects in the complement system	0.000	0.998	0.002
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
D48.7 Other specified sites	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.002	0.998	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
J69 Pneumonitis due to solids and liquids	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.002
E80.4 Gilbert's syndrome	0.002	0.998	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.002
D81.8 Other combined immunodeficiencies	0.000	0.998	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.002
D81.4 Nezelof's syndrome	0.000	0.998	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.002
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
N95.1 Menopausal and female climacteric states	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.002	0.998	0.000
D36.7 Other specified sites	0.000	0.998	0.002
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
G60.3 Idiopathic progressive neuropathy	0.002	0.998	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.002	0.998	0.000
G60.1 Refsum's disease	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.002
M94.9 Disorder of cartilage, unspecified	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.002	0.998	0.000
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.002	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
M76.69 Achilles tendinitis-Site unspec	0.000	0.998	0.002
M76.68 Achilles tendinitis-Other	0.000	0.998	0.002
M76.65 Achilles tendinitis-Pelvic/Thigh	0.000	0.998	0.002
M76.64 Achilles tendinitis-Hand	0.000	0.998	0.002
M76.63 Achilles tendinitis-Forearm	0.000	0.998	0.002
M76.62 Achilles tendinitis-Upper arm	0.000	0.998	0.002
M76.61 Achilles tendinitis-Shldr region	0.000	0.998	0.002
M76.60 Achilles tendinitis (Multiple sites)	0.000	0.998	0.002
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.002	0.998	0.000
N04.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.998	0.000
D82.1 Di George's syndrome	0.000	0.998	0.001
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
Z60.8 Other problems related to social environment	0.002	0.998	0.000
H10 Conjunctivitis	0.002	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.001	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.998	0.002
D48.4 Peritoneum	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.002
S01.1 Open wound of eyelid and periocular area	0.000	0.998	0.002
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
D48.3 Retroperitoneum	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
N05.9 Unspecified	0.002	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.001	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.001	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.001	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.001	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.001	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.001	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.001	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.001	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.001	0.998	0.000
D31.3 Choroid	0.002	0.998	0.000
S42.1 Fracture of scapula	0.002	0.998	0.000
N04 Nephrotic syndrome	0.002	0.998	0.000
N04.0 Minor glomerular abnormality	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.001	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.998	0.002
M94.19 Relapsing polychondritis (Site unspecified)	0.001	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.001	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.001	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.001	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.001	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.001	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.001	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.001	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.001	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.001	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.001	0.998	0.000
M94.38 Chondrolysis (Other)	0.001	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.001	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.001	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.001	0.998	0.000
M94.34 Chondrolysis (Hand)	0.001	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.001	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.001	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.001	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.001	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.001
Q76.5 Cervical rib	0.001	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.001	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.001	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.001	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
Z60 Problems related to social environment	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.001	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.001	0.998	0.000
H10.8 Other conjunctivitis	0.001	0.998	0.000
H10.5 Blepharoconjunctivitis	0.001	0.998	0.000
H10.2 Other acute conjunctivitis	0.001	0.998	0.000
J11.0 Influenza with pneumonia, virus not identified	0.001	0.998	0.000
Q65 Congenital deformities of hip	0.001	0.998	0.000
E50-E64 Other nutritional deficiencies	0.001	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.001	0.999	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations