TreeWAS – Variant ID: rs4915077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.373	0.626	0.001
E03.5 Myxoedema coma	0.267	0.732	0.001
E03.4 Atrophy of thyroid (acquired)	0.267	0.732	0.001
E03.3 Postinfectious hypothyroidism	0.267	0.732	0.001
E03.1 Congenital hypothyroidism without goitre	0.267	0.732	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.267	0.732	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.261	0.738	0.001
E03.8 Other specified hypothyroidism	0.219	0.780	0.001
E00-E07 Disorders of thyroid gland	0.079	0.919	0.002
E06 Thyroiditis	0.065	0.934	0.001
E07 Other disorders of thyroid	0.063	0.935	0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.057	0.942	0.002
E00 Congenital iodine-deficiency syndrome	0.057	0.942	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.057	0.942	0.002
E07.9 Disorder of thyroid, unspecified	0.054	0.946	0.000
E06.9 Thyroiditis, unspecified	0.052	0.948	0.001
E06.3 Autoimmune thyroiditis	0.051	0.948	0.001
E06.5 Other chronic thyroiditis	0.047	0.952	0.001
E06.4 Drug-induced thyroiditis	0.047	0.952	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.047	0.952	0.001
E06.1 Subacute thyroiditis	0.047	0.952	0.001
E06.0 Acute thyroiditis	0.047	0.952	0.001
E07.1 Dyshormogenetic goitre	0.046	0.953	0.001
E07.0 Hypersecretion of calcitonin	0.046	0.953	0.001
E07.8 Other specified disorders of thyroid	0.043	0.956	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.041	0.958	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.041	0.958	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.041	0.958	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.041	0.958	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.041	0.958	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.041	0.958	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.041	0.958	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.041	0.958	0.001
E05 Thyrotoxicosis [hyperthyroidism]	0.035	0.964	0.001
E05.8 Other thyrotoxicosis	0.026	0.974	0.001
E05.5 Thyroid crisis or storm	0.026	0.974	0.001
E05.4 Thyrotoxicosis factitia	0.026	0.974	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.026	0.974	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.026	0.974	0.001
E05.9 Thyrotoxicosis, unspecified	0.025	0.975	0.000
E04 Other non-toxic goitre	0.006	0.976	0.019
E04.1 Non-toxic single thyroid nodule	0.001	0.978	0.021
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.020	0.979	0.001
E04.9 Non-toxic goitre, unspecified	0.001	0.981	0.018
E04.0 Non-toxic diffuse goitre	0.004	0.982	0.014
E04.8 Other specified non-toxic goitre	0.004	0.982	0.013
E04.2 Non-toxic multinodular goitre	0.001	0.983	0.016
L40.9 Psoriasis, unspecified	0.017	0.983	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.016	0.983	0.001
L40 Psoriasis	0.013	0.987	0.000
I20.0 Unstable angina	0.000	0.988	0.012
L40.5 Arthropathic psoriasis	0.011	0.989	0.000
L40.0 Psoriasis vulgaris	0.010	0.990	0.000
L40.8 Other psoriasis	0.009	0.991	0.000
L40.4 Guttate psoriasis	0.009	0.991	0.000
L40.3 Pustulosis palmaris et plantaris	0.009	0.991	0.000
L40.2 Acrodermatitis continua	0.009	0.991	0.000
L40.1 Generalised pustular psoriasis	0.009	0.991	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.009	0.991	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.993	0.007
M54.59 Low back pain (Site unspecified)	0.000	0.993	0.007
D41.4 Bladder	0.006	0.994	0.000
G43.1 Migraine with aura [classical migraine]	0.006	0.994	0.000
C43 Malignant melanoma of skin	0.005	0.995	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.995	0.005
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.005	0.995	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.004	0.996	0.000
L40-L45 Papulosquamous disorders	0.004	0.996	0.000
G43 Migraine	0.004	0.996	0.000
C43.5 Malignant melanoma of trunk	0.004	0.996	0.000
D43.1 Brain, infratentorial	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.004	0.996	0.000
D43.4 Spinal cord	0.004	0.996	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.004	0.996	0.000
D37.7 Other digestive organs	0.004	0.996	0.000
G43.9 Migraine, unspecified	0.004	0.996	0.000
N94.6 Dysmenorrhoea, unspecified	0.004	0.996	0.000
D43.2 Brain, unspecified	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.004	0.996	0.000
C43.8 Overlapping malignant melanoma of skin	0.004	0.996	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.004	0.996	0.000
C43.0 Malignant melanoma of lip	0.004	0.996	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.004	0.996	0.000
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
C43.3 Malignant melanoma of other and unspecified parts of face	0.004	0.996	0.000
D41.9 Urinary organ, unspecified	0.004	0.996	0.000
D41.7 Other urinary organs	0.004	0.996	0.000
D41.3 Urethra	0.004	0.996	0.000
D41.2 Ureter	0.004	0.996	0.000
D41.1 Renal pelvis	0.004	0.996	0.000
G43.8 Other migraine	0.004	0.996	0.000
D37.0 Lip, oral cavity and pharynx	0.004	0.996	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
K51 Ulcerative colitis	0.000	0.996	0.004
K51.2 Ulcerative (chronic) proctitis	0.000	0.996	0.004
R06.5 Mouth breathing	0.004	0.996	0.000
D43.9 Central nervous system, unspecified	0.003	0.996	0.000
D43.7 Other parts of central nervous system	0.003	0.996	0.000
D43.3 Cranial nerves	0.003	0.996	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.996	0.000
D37.1 Stomach	0.003	0.997	0.000
D46 Myelodysplastic syndromes	0.003	0.997	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
C43.9 Malignant melanoma of skin, unspecified	0.003	0.997	0.000
D43.0 Brain, supratentorial	0.003	0.997	0.000
C43.4 Malignant melanoma of scalp and neck	0.003	0.997	0.000
L44 Other papulosquamous disorders	0.003	0.997	0.000
L41 Parapsoriasis	0.003	0.997	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.003	0.997	0.000
L42 Pityriasis rosea	0.003	0.997	0.000
G43.3 Complicated migraine	0.003	0.997	0.000
G43.2 Status migrainosus	0.003	0.997	0.000
G43.0 Migraine without aura [common migraine]	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.997	0.003
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.003	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
D41.0 Kidney	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.003	0.997	0.000
D37.9 Digestive organ, unspecified	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
D44.3 Pituitary gland	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.003	0.997	0.000
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
D37.3 Appendix	0.003	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
D48.5 Skin	0.003	0.997	0.000
E14.9 Without complications	0.000	0.997	0.003
E40-E46 Malnutrition	0.003	0.997	0.000
D37.2 Small intestine	0.003	0.997	0.000
D44.9 Endocrine gland, unspecified	0.003	0.997	0.000
D44.8 Pluriglandular involvement	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.003	0.997	0.000
D44.6 Carotid body	0.003	0.997	0.000
D44.5 Pineal gland	0.003	0.997	0.000
D44.2 Parathyroid gland	0.003	0.997	0.000
D44.1 Adrenal gland	0.003	0.997	0.000
D44.0 Thyroid gland	0.003	0.997	0.000
C21 Malignant neoplasm of anus and anal canal	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
C25.0 Head of pancreas	0.003	0.997	0.000
D38.0 Larynx	0.003	0.997	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.003	0.997	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.997	0.003
D46.2 Refractory anaemia with excess of blasts	0.003	0.997	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.003	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.003	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.003	0.997	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.003	0.997	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.003	0.997	0.000
D46.4 Refractory anaemia, unspecified	0.003	0.997	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.003	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.003	0.997	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.003	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
C25.1 Body of pancreas	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
L41.9 Parapsoriasis, unspecified	0.002	0.997	0.000
L41.8 Other parapsoriasis	0.002	0.997	0.000
L41.5 Retiform parapsoriasis	0.002	0.997	0.000
L41.4 Large plaque parapsoriasis	0.002	0.997	0.000
L41.3 Small plaque parapsoriasis	0.002	0.997	0.000
L41.2 Lymphomatoid papulosis	0.002	0.997	0.000
L41.1 Pityriasis lichenoides chronica	0.002	0.997	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.002	0.997	0.000
L44.9 Papulosquamous disorder, unspecified	0.002	0.997	0.000
L44.8 Other specified papulosquamous disorders	0.002	0.997	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.002	0.997	0.000
L44.3 Lichen ruber moniliformis	0.002	0.997	0.000
L44.2 Lichen striatus	0.002	0.997	0.000
L44.1 Lichen nitidus	0.002	0.997	0.000
L44.0 Pityriasis rubra pilaris	0.002	0.997	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.003	0.997	0.000
D38.6 Respiratory organ, unspecified	0.002	0.997	0.000
D38.5 Other respiratory organs	0.002	0.997	0.000
D38.4 Thymus	0.002	0.997	0.000
D38.3 Mediastinum	0.002	0.997	0.000
D38.2 Pleura	0.002	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
D42.9 Meninges, unspecified	0.002	0.997	0.000
D42.1 Spinal meninges	0.002	0.997	0.000
D42.0 Cerebral meninges	0.002	0.997	0.000
C23 Malignant neoplasm of gallbladder	0.003	0.997	0.000
C21.0 Anus, unspecified	0.002	0.997	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.997	0.000
C15.3 Upper third of oesophagus	0.002	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.997	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.997	0.000
D48.4 Peritoneum	0.002	0.997	0.000
D48.3 Retroperitoneum	0.002	0.997	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.002	0.997	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.003	0.997	0.000
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.002	0.998	0.000
Z93.2 Ileostomy status	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.002	0.998	0.000
C15.2 Abdominal part of oesophagus	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.002	0.998	0.000
C26.8 Overlapping lesion of digestive system	0.002	0.998	0.000
C26.1 Spleen	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
C22.7 Other specified carcinomas of liver	0.002	0.998	0.000
C22.4 Other sarcomas of liver	0.002	0.998	0.000
C22.3 Angiosarcoma of liver	0.002	0.998	0.000
C22.2 Hepatoblastoma	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
N30.9 Cystitis, unspecified	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.002	0.998	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
G40 Epilepsy	0.002	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.002	0.998	0.000
L43.8 Other lichen planus	0.002	0.998	0.000
L43.3 Subacute (active) lichen planus	0.002	0.998	0.000
L43.2 Lichenoid drug reaction	0.002	0.998	0.000
L43.1 Bullous lichen planus	0.002	0.998	0.000
L43.0 Hypertrophic lichen planus	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.002	0.998	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
R06.8 Other and unspecified abnormalities of breathing	0.002	0.998	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.002	0.998	0.000
G40.8 Other epilepsy	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
C17.2 Ileum	0.002	0.998	0.000
C17.1 Jejunum	0.002	0.998	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
D04.5 Skin of trunk	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.002	0.998	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
C17.0 Duodenum	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
C16.8 Overlapping lesion of stomach	0.001	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.001	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
C16.3 Pyloric antrum	0.001	0.998	0.000
C16.2 Body of stomach	0.001	0.998	0.000
C16.1 Fundus of stomach	0.001	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.002	0.998	0.000
C82.3 Follicular lymphoma grade IIIa	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Z00.5 Examination of potential donor of organ and tissue	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.001	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.001	0.998	0.000
C70 Malignant neoplasm of meninges	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
H36.0 Diabetic retinopathy	0.000	0.998	0.002
C67.1 Dome of bladder	0.002	0.998	0.000
D37.4 Colon	0.001	0.998	0.001
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.001	0.998	0.000
C82.2 Large cell, follicular	0.001	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.001	0.998	0.000
C20 Malignant neoplasm of rectum	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.001	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.001	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.001	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.001	0.998	0.000
E14 Unspecified diabetes mellitus	0.000	0.998	0.001
O70 Perineal laceration during delivery	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.001	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.998	0.000
N81.6 Rectocele	0.002	0.998	0.000
C18.0 Caecum	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
C18.8 Overlapping lesion of colon	0.001	0.998	0.000
W49.9 Unspecified place	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.001	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.001	0.998	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.001	0.999	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.001	0.999	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.001	0.999	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.001	0.999	0.000
C84.3 Lymphoepithelioid lymphoma	0.001	0.999	0.000
C84.2 T-zone lymphoma	0.001	0.999	0.000
C84.1 Sezary's diease	0.001	0.999	0.000
C84.0 Mycosis fungoides	0.001	0.999	0.000
H35.8 Other specified retinal disorders	0.000	0.999	0.001
H35.5 Hereditary retinal dystrophy	0.000	0.999	0.001
N30 Cystitis	0.001	0.999	0.000
C18.3 Hepatic flexure	0.001	0.999	0.000
C67.8 Overlapping lesion of bladder	0.001	0.999	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.001	0.999	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
M84.04 Malunion of fracture (Hand)	0.001	0.999	0.000
C70.9 Meninges, unspecified	0.001	0.999	0.000
C70.1 Spinal meninges	0.001	0.999	0.000
C70.0 Cerebral meninges	0.001	0.999	0.000
C72.9 Central nervous system, unspecified	0.001	0.999	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.999	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.999	0.000
C72.4 Acoustic nerve	0.001	0.999	0.000
C72.3 Optic nerve	0.001	0.999	0.000
C72.2 Olfactory nerve	0.001	0.999	0.000
C72.1 Cauda equina	0.001	0.999	0.000
C72.0 Spinal cord	0.001	0.999	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
E28 Ovarian dysfunction	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
C18.2 Ascending colon	0.001	0.999	0.000
C67.3 Anterior wall of bladder	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.999	0.000
F06.5 Organic dissociative disorder	0.001	0.999	0.000
F06.4 Organic anxiety disorder	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.999	0.000
F06.1 Organic catatonic disorder	0.001	0.999	0.000
F06.0 Organic hallucinosis	0.001	0.999	0.000
L43.9 Lichen planus, unspecified	0.001	0.999	0.000
N30.8 Other cystitis	0.001	0.999	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.001	0.999	0.000
C67.7 Urachus	0.001	0.999	0.000
C67.6 Ureteric orifice	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.001	0.999	0.000
N30.2 Other chronic cystitis	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
Z52.4 Kidney donor	0.001	0.999	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.001	0.999	0.000
E14.8 With unspecified complications	0.000	0.999	0.001
E14.7 With multiple complications	0.000	0.999	0.001
E14.6 With other specified complications	0.000	0.999	0.001
E14.5 With peripheral circulatory complications	0.000	0.999	0.001
E14.4 With neurological complications	0.000	0.999	0.001
E14.2 Withrenal complications	0.000	0.999	0.001
E14.1 With ketoacidosis	0.000	0.999	0.001
E14.0 With coma	0.000	0.999	0.001
Y42.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
Y42.4 Oral contraceptives	0.001	0.999	0.000
Y42.2 Antithyroid drugs	0.001	0.999	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.999	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.001	0.999	0.000
E63 Other nutritional deficiencies	0.001	0.999	0.000
E56 Other vitamin deficiencies	0.001	0.999	0.000
E51 Thiamine deficiency	0.001	0.999	0.000
E50 Vitamin A deficiency	0.001	0.999	0.000
E60 Dietary zinc deficiency	0.001	0.999	0.000
E59 Dietary selenium deficiency	0.001	0.999	0.000
E58 Dietary calcium deficiency	0.001	0.999	0.000
E54 Ascorbic acid deficiency	0.001	0.999	0.000
E52 Niacin deficiency [pellagra]	0.001	0.999	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
Y52 Agents primarily affecting the cardiovascular system	0.001	0.999	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.999	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.999	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
Chapter II Neoplasms	0.001	0.999	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.999	0.001
N30.4 Irradiation cystitis	0.001	0.999	0.000
I20 Angina pectoris	0.000	0.999	0.001
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
C69.9 Eye, unspecified	0.001	0.999	0.000
C69.8 Overlapping lesion of eye and adnexa	0.001	0.999	0.000
C69.6 Orbit	0.001	0.999	0.000
C69.5 Lachrymal gland and duct	0.001	0.999	0.000
C69.4 Ciliary body	0.001	0.999	0.000
C69.2 Retina	0.001	0.999	0.000
C69.1 Cornea	0.001	0.999	0.000
C69.0 Conjunctiva	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
G93.2 Benign intracranial hypertension	0.001	0.999	0.000
M84.0 Malunion of fracture	0.001	0.999	0.000
Y42.5 Other oestrogens and progestogens	0.001	0.999	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.999	0.001
C09 Malignant neoplasm of tonsil	0.001	0.999	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
Y40 Systemic antibiotics	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
C90.0 Multiple myeloma	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
Y84.6 Urinary catheterisation	0.001	0.999	0.000
H35 Other retinal disorders	0.000	0.999	0.001
G40-G47 Episodic and paroxysmal disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations