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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5013088
log Bayes Factor = 102.704
Chromosome 6   position 29,820,389  (GRCh37) Explore rs5013088 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
M07.3 Other psoriatic arthropathies
0.999 0.001 0.000
M35 Other systemic involvement of connective tissue
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
M07 Psoriatic and enteropathic arthropathies
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
B37 Candidiasis
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
B35-B49 Mycoses
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
B37.9 Candidiasis, unspecified
0.992 0.008 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.992 0.008 0.000
D70 Agranulocytosis
0.991 0.009 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.989 0.011 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.989 0.011 0.000
G30-G32 Other degenerative diseases of the nervous system
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.983 0.017 0.000
E83.1 Disorders of iron metabolism
0.000 0.022 0.978
M07.39 Other psoriatic arthropathies (Site unspecified)
0.977 0.023 0.000
B37.0 Candidal stomatitis
0.974 0.026 0.000
E16 Other disorders of pancreatic internal secretion
0.971 0.029 0.000
E10 Insulin-dependent diabetes mellitus
0.967 0.033 0.000
E16.2 Hypoglycaemia, unspecified
0.962 0.038 0.000
E03 Other hypothyroidism
0.949 0.051 0.000
L81 Other disorders of pigmentation
0.949 0.051 0.000
E06 Thyroiditis
0.948 0.052 0.000
M72 Fibroblastic disorders
0.945 0.055 0.000
M31 Other necrotising vasculopathies
0.943 0.057 0.000
G30 Alzheimer's disease
0.942 0.058 0.000
F03 Unspecified dementia
0.942 0.058 0.000
F02 Dementia in other diseases classified elsewhere
0.939 0.061 0.000
F30-F39 Mood [affective] disorders
0.938 0.062 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.927 0.073 0.000
M34 Systemic sclerosis
0.925 0.075 0.000
D73 Diseases of spleen
0.925 0.075 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.925 0.075 0.000
F01 Vascular dementia
0.920 0.080 0.000
B15-B19 Viral hepatitis
0.919 0.081 0.000
L10-L14 Bullous disorders
0.919 0.081 0.000
M86-M90 Other osteopathies
0.918 0.082 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.918 0.082 0.000
G30.9 Alzheimer's disease, unspecified
0.916 0.084 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.915 0.085 0.000
L81.9 Disorder of pigmentation, unspecified
0.914 0.086 0.000
F31 Bipolar affective disorder
0.913 0.087 0.000
L93 Lupus erythematosus
0.912 0.088 0.000
M65-M68 Disorders of synovium and tendon
0.912 0.088 0.000
M60-M63 Disorders of muscles
0.910 0.090 0.000
M24 Other specific joint derangements
0.910 0.090 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.908 0.092 0.000
E06.9 Thyroiditis, unspecified
0.903 0.097 0.000
E10.2 With renal complications
0.902 0.098 0.000
G37 Other demyelinating diseases of central nervous system
0.900 0.100 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.895 0.105 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.895 0.105 0.000
E10.1 With ketoacidosis
0.892 0.108 0.000
L89 Decubitus ulcer
0.891 0.109 0.000
L94 Other localised connective tissue disorders
0.886 0.114 0.000
M32 Systemic lupus erythematosus
0.878 0.122 0.000
M67 Other disorders of synovium and tendon
0.878 0.122 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.876 0.124 0.000
G31.8 Other specified degenerative diseases of nervous system
0.875 0.125 0.000
E03.9 Hypothyroidism, unspecified
0.875 0.125 0.000
B18 Chronic viral hepatitis
0.874 0.126 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.866 0.134 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.862 0.138 0.000
M35.7 Hypermobility syndrome
0.862 0.138 0.000
B37.3 Candidiasis of vulva and vagina
0.855 0.145 0.000
L43 Lichen planus
0.855 0.145 0.000
M62 Other disorders of muscle
0.852 0.148 0.000
L40.0 Psoriasis vulgaris
0.849 0.151 0.000
F01.9 Vascular dementia, unspecified
0.847 0.153 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.843 0.157 0.000
B37.8 Candidiasis of other sites
0.841 0.159 0.000
M89 Other disorders of bone
0.839 0.161 0.000
L83 Acanthosis nigricans
0.839 0.161 0.000
A15-A19 Tuberculosis
0.839 0.161 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.837 0.163 0.000
F02.3 Dementia in Parkinson's disease
0.831 0.169 0.000
L13 Other bullous disorders
0.830 0.170 0.000
L93.0 Discoid lupus erythematosus
0.828 0.172 0.000
M71 Other bursopathies
0.827 0.173 0.000
M79.9 Soft tissue disorder, unspecified
0.821 0.179 0.000
R47 Speech disturbances, not elsewhere classified
0.820 0.180 0.000
E14 Unspecified diabetes mellitus
0.820 0.180 0.000
M67.8 Other specified disorders of synovium and tendon
0.819 0.181 0.000
R47-R49 Symptoms and signs involving speech and voice
0.817 0.183 0.000
L81.8 Other specified disorders of pigmentation
0.816 0.184 0.000
L92.0 Granuloma annulare
0.815 0.185 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.815 0.185 0.000
R47.8 Other and unspecified speech disturbances
0.813 0.187 0.000
L40.1 Generalised pustular psoriasis
0.813 0.187 0.000
M31.6 Other giant cell arteritis
0.813 0.187 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.810 0.190 0.000
M79.1 Myalgia
0.808 0.192 0.000
E10.3 With ophthalmic complications
0.807 0.193 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.805 0.195 0.000
M34.1 CR(E)ST syndrome
0.804 0.196 0.000
B18.2 Chronic viral hepatitis C
0.804 0.196 0.000
D55-D59 Haemolytic anaemias
0.803 0.197 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.803 0.197 0.000
R47.0 Dysphasia and aphasia
0.802 0.198 0.000
B37.4 Candidiasis of other urogenital sites
0.801 0.199 0.000
F32 Depressive episode
0.800 0.200 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.799 0.201 0.000
L40.4 Guttate psoriasis
0.799 0.201 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.797 0.203 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.796 0.204 0.000
M62.8 Other specified disorders of muscle
0.796 0.204 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.795 0.205 0.000
A65-A69 Other spirochaetal diseases
0.793 0.207 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.791 0.209 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.209 0.791
D73.4 Cyst of spleen
0.789 0.211 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.786 0.214 0.000
M07.38 Other psoriatic arthropathies (Other)
0.785 0.215 0.000
D73.5 Infarction of spleen
0.785 0.215 0.000
M34.9 Systemic sclerosis, unspecified
0.785 0.215 0.000
M11 Other crystal arthropathies
0.784 0.216 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
L94.2 Calcinosis cutis
0.782 0.218 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.781 0.219 0.000
A20-A28 Certain zoonotic bacterial diseases
0.780 0.220 0.000
L91 Hypertrophic disorders of skin
0.776 0.224 0.000
F80-F89 Disorders of psychological development
0.776 0.224 0.000
M31.1 Thrombotic microangiopathy
0.775 0.225 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.773 0.227 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.772 0.228 0.000
L40.3 Pustulosis palmaris et plantaris
0.772 0.228 0.000
K90 Intestinal malabsorption
0.771 0.228 0.001
B65-B83 Helminthiases
0.771 0.229 0.000
E10.9 Without complications
0.770 0.230 0.000
R49 Voice disturbances
0.770 0.230 0.000
M79.7 Fibromyalgia
0.770 0.230 0.000
M86 Osteomyelitis
0.770 0.230 0.000
E13 Other specified diabetes mellitus
0.769 0.231 0.000
G31.0 Circumscribed brain atrophy
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.767 0.233 0.000
L13.0 Dermatitis herpetiformis
0.767 0.233 0.000
M35.8 Other specified systemic involvement of connective tissue
0.766 0.234 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.766 0.234 0.000
F02.0 Dementia in Pick's disease
0.764 0.236 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.763 0.237 0.000
B17 Other acute viral hepatitis
0.761 0.239 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.760 0.240 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.760 0.240 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.759 0.241 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.758 0.242 0.000
B18.9 Chronic viral hepatitis, unspecified
0.757 0.243 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.756 0.244 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.754 0.246 0.000
M35.1 Other overlap syndromes
0.753 0.246 0.000
M08 Juvenile arthritis
0.753 0.247 0.000
M33 Dermatopolymyositis
0.752 0.248 0.000
M24.2 Disorder of ligament
0.751 0.249 0.000
M31.7 Microscopic polyangiitis
0.751 0.249 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.751 0.249 0.000
E03.8 Other specified hypothyroidism
0.749 0.250 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.746 0.254 0.000
M10 Gout
0.745 0.255 0.000
L81.0 Postinflammatory hyperpigmentation
0.745 0.255 0.000
K51 Ulcerative colitis
0.000 0.256 0.744
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.742 0.258 0.000
D73.8 Other diseases of spleen
0.741 0.258 0.000
F01.1 Multi-infarct dementia
0.741 0.259 0.000
G36 Other acute disseminated demyelination
0.741 0.259 0.000
M67.4 Ganglion
0.741 0.259 0.000
K50-K52 Noninfective enteritis and colitis
0.018 0.260 0.723
M31.3 Wegener's granulomatosis
0.739 0.261 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.739 0.261 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.737 0.263 0.000
L43.9 Lichen planus, unspecified
0.736 0.264 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.736 0.264 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.735 0.265 0.000
M70.5 Other bursitis of knee
0.735 0.265 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.734 0.266 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.734 0.266 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.734 0.266 0.000
F31.8 Other bipolar affective disorders
0.734 0.266 0.000
D73.9 Disease of spleen, unspecified
0.733 0.267 0.000
L91.0 Keloid scar
0.729 0.271 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.729 0.271 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.271 0.728
R49.0 Dysphonia
0.728 0.272 0.000
G62 Other polyneuropathies
0.728 0.272 0.000
B36 Other superficial mycoses
0.726 0.274 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.726 0.274 0.000
L93.1 Subacute cutaneous lupus erythematosus
0.725 0.275 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.724 0.276 0.000
M24.1 Other articular cartilage disorders
0.724 0.276 0.000
M07.6 Other enteropathic arthropathies
0.723 0.277 0.000
E06.5 Other chronic thyroiditis
0.723 0.277 0.000
B37.7 Candidal septicaemia
0.721 0.279 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
L44 Other papulosquamous disorders
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.716 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.716 0.284 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.716 0.284 0.000
M35.5 Multifocal fibrosclerosis
0.716 0.284 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.716 0.284 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
M07.5 Arthropathy in ulcerative colitis
0.716 0.284 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.716 0.284 0.000
M07.2 Psoriatic spondylitis
0.716 0.284 0.000
M07.1 Arthritis mutilans
0.716 0.284 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
B44 Aspergillosis
0.716 0.284 0.000
L89.3 Stage IV decubitus ulcer
0.716 0.284 0.000
B37.6 Candidal endocarditis
0.715 0.284 0.000
B37.5 Candidal meningitis
0.715 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
B48 Other mycoses, not elsewhere classified
0.715 0.285 0.000
B47 Mycetoma
0.715 0.285 0.000
B46 Zygomycosis
0.715 0.285 0.000
B45 Cryptococcosis
0.715 0.285 0.000
B43 Chromomycosis and phaeomycotic abscess
0.715 0.285 0.000
B42 Sporotrichosis
0.715 0.285 0.000
B41 Paracoccidioidomycosis
0.715 0.285 0.000
B40 Blastomycosis
0.715 0.285 0.000
B39 Histoplasmosis
0.715 0.285 0.000
B38 Coccidioidomycosis
0.715 0.285 0.000
K50.9 Crohn's disease, unspecified
0.000 0.286 0.714
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.287 0.713
F50 Eating disorders
0.713 0.287 0.000
E10.8 With unspecified complications
0.713 0.287 0.000
D74 Methaemoglobinaemia
0.712 0.287 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.712 0.287 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.712 0.287 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.712 0.288 0.000
Q00-Q07 Congenital malformations of the nervous system
0.711 0.289 0.000
M89.5 Osteolysis
0.710 0.290 0.000
L11 Other acantholytic disorders
0.710 0.290 0.000
F09 Unspecified organic or symptomatic mental disorder
0.709 0.291 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.709 0.291 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.709 0.291 0.000
E10.7 With multiple complications
0.709 0.291 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.709 0.291 0.000
L87 Transepidermal elimination disorders
0.709 0.291 0.000
L86 Keratoderma in diseases classified elsewhere
0.709 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
E05.8 Other thyrotoxicosis
0.708 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.293 0.000
L12 Pemphigoid
0.707 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.295 0.000
E15 Nondiabetic hypoglycaemic coma
0.705 0.295 0.000
M71.3 Other bursal cyst
0.704 0.296 0.000
M89.3 Hypertrophy of bone
0.704 0.296 0.000
L94.0 Localised scleroderma [morphea]
0.703 0.297 0.000
M77 Other enthesopathies
0.703 0.297 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.702 0.298 0.000
M31.8 Other specified necrotising vasculopathies
0.700 0.299 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.301 0.699
G62.9 Polyneuropathy, unspecified
0.699 0.301 0.000
M34.8 Other forms of systemic sclerosis
0.699 0.301 0.000
F32.0 Mild depressive episode
0.699 0.301 0.000
D72 Other disorders of white blood cells
0.698 0.302 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.303 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.696 0.304 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.696 0.304 0.000
E16.4 Abnormal secretion of gastrin
0.696 0.304 0.000
E16.3 Increased secretion of glucagon
0.696 0.304 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.696 0.304 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.696 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.695 0.304 0.000
F23 Acute and transient psychotic disorders
0.695 0.305 0.000
E14.5 With peripheral circulatory complications
0.690 0.310 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.690 0.310 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.310 0.690
E06.3 Autoimmune thyroiditis
0.690 0.310 0.000
M25 Other joint disorders, not elsewhere classified
0.689 0.311 0.000
M70.6 Trochanteric bursitis
0.688 0.312 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.688 0.312 0.000
E10.6 With other specified complications
0.687 0.313 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.687 0.313 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.686 0.314 0.000
M70.2 Olecranon bursitis
0.685 0.315 0.000
E14.3 With ophthalmic complications
0.684 0.316 0.000
E11 Non-insulin-dependent diabetes mellitus
0.684 0.316 0.000
D60-D64 Aplastic and other anaemias
0.683 0.317 0.000
F25 Schizoaffective disorders
0.683 0.317 0.000
M79.18 Myalgia (Other)
0.683 0.317 0.000
K90.9 Intestinal malabsorption, unspecified
0.682 0.318 0.000
E03.5 Myxoedema coma
0.681 0.319 0.000
E03.4 Atrophy of thyroid (acquired)
0.681 0.319 0.000
E03.3 Postinfectious hypothyroidism
0.681 0.319 0.000
E03.1 Congenital hypothyroidism without goitre
0.681 0.319 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.681 0.319 0.000
L81.7 Pigmented purpuric dermatosis
0.681 0.319 0.000
L81.6 Other disorders of diminished melanin formation
0.681 0.319 0.000
L81.5 Leukoderma, not elsewhere classified
0.681 0.319 0.000
L81.3 Cafe au lait spots
0.681 0.319 0.000
L81.1 Chloasma
0.681 0.319 0.000
B35 Dermatophytosis
0.680 0.320 0.000
L93.2 Other local lupus erythematosus
0.680 0.320 0.000
E06.4 Drug-induced thyroiditis
0.680 0.320 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.680 0.320 0.000
E06.1 Subacute thyroiditis
0.680 0.320 0.000
E06.0 Acute thyroiditis
0.680 0.320 0.000
M89.9 Disorder of bone, unspecified
0.680 0.320 0.000
M72.9 Fibroblastic disorder, unspecified
0.678 0.322 0.000
M72.8 Other fibroblastic disorders
0.678 0.322 0.000
M72.6 Necrotizing fasciitis
0.678 0.322 0.000
M72.5 Fasciitis, not elsewhere classified
0.678 0.322 0.000
M72.4 Pseudosarcomatous fibromatosis
0.678 0.322 0.000
M72.3 Nodular fasciitis
0.678 0.322 0.000
M72.1 Knuckle pads
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.322 0.000
M62.0 Diastasis of muscle
0.678 0.322 0.000
M35.2 Behcet's disease
0.677 0.323 0.000
L88 Pyoderma gangrenosum
0.677 0.323 0.000
M34.0 Progressive systemic sclerosis
0.677 0.323 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.676 0.324 0.000
M31.2 Lethal midline granuloma
0.676 0.324 0.000
G30.8 Other Alzheimer's disease
0.675 0.324 0.000
G30.1 Alzheimer's disease with late onset
0.675 0.324 0.000
D80-D89 Certain disorders involving the immune mechanism
0.675 0.325 0.000
B49 Unspecified mycosis
0.674 0.325 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.674 0.326 0.000
E10.4 With neurological complications
0.673 0.327 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.673 0.327 0.000
F02.2 Dementia in Huntington's disease
0.673 0.327 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.673 0.327 0.000
F38 Other mood [affective] disorders
0.673 0.327 0.000
M79.0 Rheumatism, unspecified
0.673 0.327 0.000
M79.70 Fibromyalgia (Multiple sites)
0.669 0.331 0.000
F30 Manic episode
0.669 0.331 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.669 0.331 0.000
D73.1 Hypersplenism
0.668 0.332 0.000
M67.1 Other contracture of tendon (sheath)
0.667 0.333 0.000
K50.8 Other Crohn's disease
0.000 0.333 0.667
B37.2 Candidiasis of skin and nail
0.665 0.335 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.665 0.335 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.665 0.335 0.000
L94.8 Other specified localised connective tissue disorders
0.664 0.336 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.663 0.336 0.000
D73.3 Abscess of spleen
0.663 0.337 0.000
D73.2 Chronic congestive splenomegaly
0.663 0.337 0.000
K50.0 Crohn's disease of small intestine
0.000 0.337 0.663
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.663 0.337 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.663 0.337 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.663 0.337 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.663 0.337 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.663 0.337 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.663 0.337 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.663 0.337 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.663 0.337 0.000
M24.6 Ankylosis of joint
0.663 0.337 0.000
M79.16 Myalgia (Lower leg)
0.663 0.337 0.000
B99-B99 Other infectious diseases
0.662 0.338 0.000
K51.4 Pseudopolyposis of colon
0.000 0.338 0.661
M70.3 Other bursitis of elbow
0.661 0.339 0.000
F31.7 Bipolar affective disorder, currently in remission
0.660 0.339 0.000
F01.8 Other vascular dementia
0.659 0.341 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.659 0.341 0.000
F01.2 Subcortical vascular dementia
0.659 0.341 0.000
F01.0 Vascular dementia of acute onset
0.659 0.341 0.000
L14 Bullous disorders in diseases classified elsewhere
0.659 0.341 0.000
M71.9 Bursopathy, unspecified
0.659 0.341 0.000
L10 Pemphigus
0.658 0.342 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.658 0.342 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.657 0.343 0.000
M87 Osteonecrosis
0.657 0.343 0.000
F05.9 Delirium, unspecified
0.655 0.345 0.000
A18 Tuberculosis of other organs
0.655 0.345 0.000
M79.5 Residual foreign body in soft tissue
0.654 0.346 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.654 0.346 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.653 0.347 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.653 0.347 0.000
M61 Calcification and ossification of muscle
0.653 0.347 0.000
M24.9 Joint derangement, unspecified
0.652 0.347 0.000
L89.2 Stage III decubitus ulcer
0.652 0.348 0.000
M67.43 Ganglion, wrist
0.652 0.348 0.000
B37.1 Pulmonary candidiasis
0.651 0.348 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.651 0.349 0.000
F39 Unspecified mood [affective] disorder
0.649 0.351 0.000
F80 Specific developmental disorders of speech and language
0.648 0.352 0.000
F70-F79 Mental retardation
0.647 0.353 0.000
M76 Enthesopathies of lower limb, excluding foot
0.647 0.353 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.647 0.353 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.647 0.353 0.000
A69 Other spirochaetal infections
0.646 0.354 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.645 0.355 0.000
L40.8 Other psoriasis
0.645 0.355 0.000
G37.5 Concentric sclerosis [Balo]
0.645 0.355 0.000
G37.4 Subacute necrotising myelitis
0.645 0.355 0.000
G37.2 Central pontine myelinolysis
0.645 0.355 0.000
G37.1 Central demyelination of corpus callosum
0.645 0.355 0.000
G37.0 Diffuse sclerosis
0.645 0.355 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.645 0.355 0.000
G31.2 Degeneration of nervous system due to alcohol
0.644 0.356 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.644 0.356 0.000
M00-M03 Infectious arthropathies
0.643 0.357 0.000
L43.8 Other lichen planus
0.642 0.357 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.642 0.358 0.000
E11.1 With ketoacidosis
0.642 0.358 0.000
M79.19 Myalgia (Site unspecified)
0.642 0.358 0.000
M31.9 Necrotising vasculopathy, unspecified
0.641 0.358 0.000
M79.3 Panniculitis, unspecified
0.641 0.358 0.000
M70.56 Other bursitis of knee-Lower Leg
0.641 0.359 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.641 0.359 0.000
M31.0 Hypersensitivity angiitis
0.640 0.360 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.639 0.361 0.000
M67.0 Short Achilles tendon (acquired)
0.638 0.362 0.000
M79.94 Soft tissue disorder, unspecified (Hand)
0.637 0.363 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.637 0.363 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.637 0.363 0.000
L94.6 Ainhum
0.635 0.365 0.000
L94.5 Poikiloderma vasculare atrophicans
0.635 0.365 0.000
L94.4 Gottron's papules
0.635 0.365 0.000
L94.3 Sclerodactyly
0.635 0.365 0.000
L94.1 Linear scleroderma
0.635 0.365 0.000
M11.2 Other chondrocalcinosis
0.635 0.365 0.000
D59 Acquired haemolytic anaemia
0.635 0.365 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.634 0.366 0.000
E14.1 With ketoacidosis
0.634 0.366 0.000
M24.26 Disorder of ligament (Lower leg)
0.633 0.367 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.632 0.367 0.000
E14.0 With coma
0.631 0.369 0.000
M90 Osteopathies in diseases classified elsewhere
0.630 0.370 0.000
M86.9 Osteomyelitis, unspecified
0.630 0.370 0.000
E10.0 With coma
0.630 0.370 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.629 0.370 0.000
M32.8 Other forms of systemic lupus erythematosus
0.629 0.370 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.629 0.370 0.000
F31.9 Bipolar affective disorder, unspecified
0.630 0.370 0.000
M60 Myositis
0.629 0.370 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.629 0.371 0.000
M67.3 Transient synovitis
0.629 0.371 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.629 0.371 0.000
B16 Acute hepatitis B
0.628 0.372 0.000
D76.3 Other histiocytosis syndromes
0.628 0.372 0.000
R29.6 Tendency to fall, not elsewhere classified
0.628 0.372 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.627 0.372 0.000
M94 Other disorders of cartilage
0.627 0.373 0.000
B18.8 Other chronic viral hepatitis
0.627 0.373 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.627 0.373 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.374 0.626
M25.9 Joint disorder, unspecified
0.625 0.375 0.000
A28 Other zoonotic bacterial diseases, not elsewhere classified
0.624 0.376 0.000
L42 Pityriasis rosea
0.623 0.377 0.000
E14.8 With unspecified complications
0.623 0.377 0.000
M25.7 Osteophyte
0.623 0.377 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.621 0.379 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.621 0.379 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.621 0.379 0.000
M70.1 Bursitis of hand
0.621 0.379 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.621 0.379 0.000
L95.9 Vasculitis limited to skin, unspecified
0.620 0.380 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.619 0.380 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.617 0.383 0.000
F05.0 Delirium not superimposed on dementia, so described
0.616 0.383 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.616 0.384 0.000
M86.6 Other chronic osteomyelitis
0.615 0.385 0.000
M79.8 Other specified soft tissue disorders
0.614 0.386 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.613 0.387 0.000
L43.3 Subacute (active) lichen planus
0.613 0.387 0.000
L43.2 Lichenoid drug reaction
0.613 0.387 0.000
L43.1 Bullous lichen planus
0.613 0.387 0.000
L43.0 Hypertrophic lichen planus
0.613 0.387 0.000
L94.9 Localised connective tissue disorder, unspecified
0.613 0.387 0.000
G30.0 Alzheimer's disease with early onset
0.612 0.387 0.000
M70.7 Other bursitis of hip
0.612 0.388 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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