TreeWAS – Variant ID: rs55777621

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
E03.9 Hypothyroidism, unspecified	0.999	0.001
M20-M25 Other joint disorders	0.999	0.001
N30-N39 Other diseases of urinary system	0.999	0.001
E03 Other hypothyroidism	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
E00-E07 Disorders of thyroid gland	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
Chapter XI Diseases of the digestive system	0.994	0.006
Chapter VIII Diseases of the ear and mastoid process	0.990	0.010
J30-J39 Other diseases of upper respiratory tract	0.990	0.010
N40-N51 Diseases of male genital organs	0.989	0.011
N39 Other disorders of urinary system	0.989	0.011
Chapter X Diseases of the respiratory system	0.988	0.012
J32 Chronic sinusitis	0.988	0.012
M20 Acquired deformities of fingers and toes	0.986	0.014
N40 Hyperplasia of prostate	0.983	0.017
H90-H95 Other disorders of ear	0.983	0.017
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.982	0.018
K55-K64 Other diseases of intestines	0.981	0.019
J32.9 Chronic sinusitis, unspecified	0.980	0.020
K60 Fissure and fistula of anal and rectal regions	0.975	0.025
M70-M79 Other soft tissue disorders	0.975	0.025
M75 Shoulder lesions	0.970	0.030
K50-K52 Noninfective enteritis and colitis	0.969	0.031
N60-N64 Disorders of breast	0.969	0.031
K61 Abscess of anal and rectal regions	0.963	0.037
N30 Cystitis	0.963	0.037
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.956	0.044
N39.4 Other specified urinary incontinence	0.956	0.044
K60.2 Anal fissure, unspecified	0.955	0.045
K13 Other diseases of lip and oral mucosa	0.954	0.046
H91 Other hearing loss	0.952	0.048
K61.0 Anal abscess	0.949	0.051
N70-N77 Inflammatory diseases of female pelvic organs	0.948	0.052
S60-S69 Injuries to the wrist and hand	0.943	0.057
S40-S49 Injuries to the shoulder and upper arm	0.942	0.058
M20.1 Hallux valgus (acquired)	0.937	0.063
K13.0 Diseases of lips	0.935	0.065
M65-M68 Disorders of synovium and tendon	0.932	0.068
Chapter I Certain infectious and parasitic diseases	0.931	0.069
M75.1 Rotator cuff syndrome	0.930	0.070
J31.0 Chronic rhinitis	0.930	0.070
N60 Benign mammary dysplasia	0.930	0.070
H91.9 Hearing loss, unspecified	0.930	0.070
K50 Crohn's disease [regional enteritis]	0.929	0.071
H90 Conductive and sensorineural hearing loss	0.921	0.079
M34 Systemic sclerosis	0.920	0.080
T15-T19 Effects of foreign body entering through natural orifice	0.918	0.082
N99-N99 Other disorders of the genitourinary system	0.914	0.086
N72 Inflammatory disease of cervix uteri	0.909	0.091
M24 Other specific joint derangements	0.908	0.092
M75.4 Impingement syndrome of shoulder	0.908	0.092
E06 Thyroiditis	0.899	0.101
N30.9 Cystitis, unspecified	0.896	0.104
K60.3 Anal fistula	0.894	0.106
M22 Disorders of patella	0.891	0.109
M67 Other disorders of synovium and tendon	0.890	0.110
K09 Cysts of oral region, not elsewhere classified	0.886	0.114
M20.4 Other hammer toe(s) (acquired)	0.885	0.115
K40-K46 Hernia	0.881	0.119
J35 Chronic diseases of tonsils and adenoids	0.879	0.121
K04 Diseases of pulp and periapical tissues	0.877	0.123
M75.3 Calcific tendinitis of shoulder	0.874	0.126
S80-S89 Injuries to the knee and lower leg	0.873	0.127
N32 Other disorders of bladder	0.869	0.131
M20.5 Other deformities of toe(s) (acquired)	0.867	0.133
T18 Foreign body in alimentary tract	0.867	0.133
N39.0 Urinary tract infection, site not specified	0.866	0.134
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.865	0.135
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.865	0.135
Chapter VI Diseases of the nervous system	0.863	0.137
K14 Diseases of tongue	0.856	0.144
M67.8 Other specified disorders of synovium and tendon	0.856	0.144
N39.8 Other specified disorders of urinary system	0.854	0.146
S66 Injury of muscle and tendon at wrist and hand level	0.853	0.147
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.852	0.148
K50.9 Crohn's disease, unspecified	0.850	0.150
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.848	0.152
N30.1 Interstitial cystitis (chronic)	0.848	0.152
G90-G99 Other disorders of the nervous system	0.845	0.155
B95-B98 Bacterial, viral and other infectious agents	0.844	0.156
K43 Ventral hernia	0.842	0.157
N60.0 Solitary cyst of breast	0.839	0.161
M31 Other necrotising vasculopathies	0.836	0.164
T18.1 Foreign body in oesophagus	0.830	0.170
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.829	0.171
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.826	0.173
J32.2 Chronic ethmoidal sinusitis	0.826	0.174
K62 Other diseases of anus and rectum	0.826	0.174
N39.1 Persistent proteinuria, unspecified	0.824	0.176
K51 Ulcerative colitis	0.822	0.178
S10-S19 Injuries to the neck	0.822	0.178
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.817	0.183
K10 Other diseases of jaws	0.817	0.183
K43.9 Ventral hernia without obstruction or gangrene	0.816	0.184
N64 Other disorders of breast	0.813	0.187
J32.0 Chronic maxillary sinusitis	0.812	0.188
N60.8 Other benign mammary dysplasias	0.810	0.190
E70-E90 Metabolic disorders	0.809	0.191
H65-H75 Diseases of middle ear and mastoid	0.808	0.192
N41 Inflammatory diseases of prostate	0.804	0.196
J32.4 Chronic pansinusitis	0.804	0.196
K60.5 Anorectal fistula	0.804	0.196
M20.6 Acquired deformity of toe(s), unspecified	0.802	0.198
N35 Urethral stricture	0.802	0.198
N45 Orchitis and epididymitis	0.800	0.200
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.797	0.203
N60.1 Diffuse cystic mastopathy	0.797	0.203
N50 Other disorders of male genital organs	0.797	0.203
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.796	0.204
G35-G37 Demyelinating diseases of the central nervous system	0.795	0.205
E06.3 Autoimmune thyroiditis	0.795	0.205
J35.8 Other chronic diseases of tonsils and adenoids	0.794	0.206
M24.4 Recurrent dislocation and subluxation of joint	0.794	0.206
K50.1 Crohn's disease of large intestine	0.791	0.209
J40-J47 Chronic lower respiratory diseases	0.790	0.210
M22.4 Chondromalacia patellae	0.788	0.212
K04.7 Periapical abscess without sinus	0.787	0.213
J60-J70 Lung diseases due to external agents	0.787	0.213
A00-A09 Intestinal infectious diseases	0.785	0.215
J38.3 Other diseases of vocal cords	0.784	0.216
N62 Hypertrophy of breast	0.784	0.216
K60.0 Acute anal fissure	0.780	0.220
T79-T79 Certain early complications of trauma	0.780	0.220
M34.1 CR(E)ST syndrome	0.779	0.221
S40 Superficial injury of shoulder and upper arm	0.776	0.224
M34.9 Systemic sclerosis, unspecified	0.775	0.225
H90.2 Conductive hearing loss, unspecified	0.775	0.225
K09.8 Other cysts of oral region, not elsewhere classified	0.774	0.226
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.774	0.226
M20.2 Hallux rigidus	0.772	0.228
G90 Disorders of autonomic nervous system	0.772	0.228
S62 Fracture at wrist and hand level	0.770	0.230
K51.9 Ulcerative colitis, unspecified	0.769	0.231
K55 Vascular disorders of intestine	0.769	0.231
S50-S59 Injuries to the elbow and forearm	0.766	0.234
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.763	0.236
B35-B49 Mycoses	0.763	0.236
J32.8 Other chronic sinusitis	0.763	0.237
K04.6 Periapical abscess with sinus	0.763	0.237
K62.8 Other specified diseases of anus and rectum	0.762	0.238
M23 Internal derangement of knee	0.760	0.240
N32.3 Diverticulum of bladder	0.760	0.240
K00 Disorders of tooth development and eruption	0.758	0.242
N99.3 Prolapse of vaginal vault after hysterectomy	0.758	0.242
S46 Injury of muscle and tendon at shoulder and upper arm level	0.757	0.243
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.757	0.243
H92 Otalgia and effusion of ear	0.756	0.244
S64 Injury of nerves at wrist and hand level	0.756	0.244
S61 Open wound of wrist and hand	0.754	0.246
M24.1 Other articular cartilage disorders	0.754	0.246
K62.7 Radiation proctitis	0.753	0.247
J47 Bronchiectasis	0.752	0.248
N32.8 Other specified disorders of bladder	0.751	0.249
N43 Hydrocele and spermatocele	0.751	0.249
M35 Other systemic involvement of connective tissue	0.751	0.249
M75.0 Adhesive capsulitis of shoulder	0.750	0.250
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.750	0.250
K13.6 Irritative hyperplasia of oral mucosa	0.748	0.251
K52 Other non-infective gastro-enteritis and colitis	0.744	0.256
S43.0 Dislocation of shoulder joint	0.744	0.256
G91 Hydrocephalus	0.742	0.258
E65-E68 Obesity and other hyperalimentation	0.740	0.260
H65 Nonsuppurative otitis media	0.738	0.262
T91 Sequelae of injuries of neck and trunk	0.737	0.263
G95 Other diseases of spinal cord	0.736	0.264
M86-M90 Other osteopathies	0.736	0.264
N99.8 Other postprocedural disorders of genito-urinary system	0.736	0.264
E78.5 Hyperlipidaemia, unspecified	0.736	0.264
M22.2 Patellofemoral disorders	0.736	0.264
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.735	0.265
J40 Bronchitis, not specified as acute or chronic	0.734	0.266
S81 Open wound of lower leg	0.734	0.266
M34.8 Other forms of systemic sclerosis	0.733	0.267
J37 Chronic laryngitis and laryngotracheitis	0.732	0.268
N30.2 Other chronic cystitis	0.732	0.268
K14.0 Glossitis	0.732	0.268
J34 Other disorders of nose and nasal sinuses	0.731	0.269
K40 Inguinal hernia	0.730	0.270
G35 Multiple sclerosis	0.730	0.270
E06.9 Thyroiditis, unspecified	0.728	0.272
N34 Urethritis and urethral syndrome	0.728	0.272
M75.9 Shoulder lesion, unspecified	0.728	0.272
S70-S79 Injuries to the hip and thigh	0.727	0.273
J30 Vasomotor and allergic rhinitis	0.726	0.274
S80 Superficial injury of lower leg	0.726	0.274
H60-H62 Diseases of external ear	0.725	0.275
N48 Other disorders of penis	0.724	0.276
A08 Viral and other specified intestinal infections	0.723	0.277
E07 Other disorders of thyroid	0.723	0.277
E78.9 Disorder of lipoprotein metabolism, unspecified	0.723	0.277
B50-B64 Protozoal diseases	0.723	0.277
N30.8 Other cystitis	0.723	0.277
K62.6 Ulcer of anus and rectum	0.722	0.278
N64.9 Disorder of breast, unspecified	0.721	0.279
M71 Other bursopathies	0.720	0.280
K09.0 Developmental odontogenic cysts	0.719	0.281
H93 Other disorders of ear, not elsewhere classified	0.718	0.282
K06 Other disorders of gingiva and edentulous alveolar ridge	0.717	0.282
N50.1 Vascular disorders of male genital organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284
M33 Dermatopolymyositis	0.716	0.284
M32 Systemic lupus erythematosus	0.716	0.284
M30 Polyarteritis nodosa and related conditions	0.716	0.284
N37 Urethral disorders in diseases classified elsewhere	0.716	0.284
N33 Bladder disorders in diseases classified elsewhere	0.716	0.284
E03.8 Other specified hypothyroidism	0.715	0.284
E03.5 Myxoedema coma	0.715	0.284
E03.4 Atrophy of thyroid (acquired)	0.715	0.284
E03.3 Postinfectious hypothyroidism	0.715	0.284
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.715	0.284
E03.1 Congenital hypothyroidism without goitre	0.715	0.284
E03.0 Congenital hypothyroidism with diffuse goitre	0.715	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
K50.0 Crohn's disease of small intestine	0.715	0.285
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.715	0.285
E00 Congenital iodine-deficiency syndrome	0.715	0.285
E02 Subclinical iodine-deficiency hypothyroidism	0.715	0.285
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.714	0.286
J31.2 Chronic pharyngitis	0.714	0.286
K61.3 Ischiorectal abscess	0.713	0.287
S49 Other and unspecified injuries of shoulder and upper arm	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289
N51 Disorders of male genital organs in diseases classified elsewhere	0.709	0.291
N46 Male infertility	0.709	0.291
N44 Torsion of testis	0.709	0.291
G00-G09 Inflammatory diseases of the central nervous system	0.709	0.291
N39.2 Orthostatic proteinuria, unspecified	0.709	0.291
J32.3 Chronic sphenoidal sinusitis	0.708	0.292
J32.1 Chronic frontal sinusitis	0.708	0.292
N60.3 Fibrosclerosis of breast	0.708	0.292
E50-E64 Other nutritional deficiencies	0.706	0.293
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.706	0.294
H90.0 Conductive hearing loss, bilateral	0.706	0.294
B25-B34 Other viral diseases	0.706	0.294
M23.3 Other meniscus derangements	0.705	0.295
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.704	0.295
H94 Other disorders of ear in diseases classified elsewhere	0.704	0.295
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.704	0.296
M21 Other acquired deformities of limbs	0.704	0.296
K03 Other diseases of hard tissues of teeth	0.704	0.296
K64 Haemorrhoids and perianal venous thrombosis	0.704	0.296
K50.8 Other Crohn's disease	0.702	0.298
S68 Traumatic amputation of wrist and hand	0.702	0.298
K60.4 Rectal fistula	0.699	0.301
H90.3 Sensorineural hearing loss, bilateral	0.699	0.301
M76 Enthesopathies of lower limb, excluding foot	0.699	0.301
M73 Soft tissue disorders in diseases classified elsewhere	0.699	0.301
Q80-Q89 Other congenital malformations	0.699	0.301
M91-M94 Chondropathies	0.699	0.301
N39.9 Disorder of urinary system, unspecified	0.699	0.301
K05 Gingivitis and periodontal diseases	0.698	0.302
K10.2 Inflammatory conditions of jaws	0.697	0.303
S82 Fracture of lower leg, including ankle	0.697	0.303
S90-S99 Injuries to the ankle and foot	0.696	0.304
M75.8 Other shoulder lesions	0.696	0.304
S60 Superficial injury of wrist and hand	0.694	0.305
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.693	0.307
M77 Other enthesopathies	0.693	0.307
S42 Fracture of shoulder and upper arm	0.693	0.307
M24.2 Disorder of ligament	0.693	0.307
K61.4 Intrasphincteric abscess	0.691	0.309
K61.2 Anorectal abscess	0.691	0.309
K61.1 Rectal abscess	0.691	0.309
N30.4 Irradiation cystitis	0.690	0.310
N30.0 Acute cystitis	0.690	0.310
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.690	0.310
S62.3 Fracture of other metacarpal bone	0.689	0.311
B15-B19 Viral hepatitis	0.688	0.312
J35.0 Chronic tonsillitis	0.687	0.313
J31.1 Chronic nasopharyngitis	0.686	0.314
N10-N16 Renal tubulo-interstitial diseases	0.684	0.315
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.684	0.316
K13.5 Oral submucous fibrosis	0.684	0.316
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.684	0.316
K13.3 Hairy leukoplakia	0.684	0.316
K13.1 Cheek and lip biting	0.684	0.316
H91.8 Other specified hearing loss	0.682	0.317
H91.3 Deaf mutism, not elsewhere classified	0.682	0.317
H91.2 Sudden idiopathic hearing loss	0.682	0.317
H91.1 Presbycusis	0.682	0.317
H91.0 Ototoxic hearing loss	0.682	0.317
A08.4 Viral intestinal infection, unspecified	0.681	0.319
B99-B99 Other infectious diseases	0.681	0.319
E78.0 Pure hypercholesterolaemia	0.680	0.320
N36 Other disorders of urethra	0.680	0.320
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.679	0.320
T66-T78 Other and unspecified effects of external causes	0.679	0.321
T36-T50 Poisoning by drugs, medicaments and biological substances	0.679	0.321
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.679	0.321
B65-B83 Helminthiases	0.679	0.321
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.677	0.323
A50-A64 Infections with a predominantly sexual mode of transmission	0.676	0.324
S65 Injury of blood vessels at wrist and hand level	0.676	0.324
K14.9 Disease of tongue, unspecified	0.676	0.324
S48 Traumatic amputation of shoulder and upper arm	0.675	0.325
S45 Injury of blood vessels at shoulder and upper arm level	0.675	0.325
S44 Injury of nerves at shoulder and upper arm level	0.675	0.325
S41 Open wound of shoulder and upper arm	0.675	0.325
S47 Crushing injury of shoulder and upper arm	0.675	0.325
J38.7 Other diseases of larynx	0.675	0.325
N73 Other female pelvic inflammatory diseases	0.674	0.326
M80-M85 Disorders of bone density and structure	0.672	0.328
N71 Inflammatory disease of uterus, except cervix	0.671	0.329
S86 Injury of muscle and tendon at lower leg level	0.671	0.329
B20-B24 Human immunodeficiency virus [HIV] disease	0.670	0.330
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.668	0.332
M66 Spontaneous rupture of synovium and tendon	0.668	0.332
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.668	0.332
B85-B89 Pediculosis, acariasis and other infestations	0.668	0.332
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.668	0.332
A75-A79 Rickettsioses	0.668	0.332
A70-A74 Other diseases caused by chlamydiae	0.668	0.332
A65-A69 Other spirochaetal diseases	0.668	0.332
A20-A28 Certain zoonotic bacterial diseases	0.668	0.332
A15-A19 Tuberculosis	0.668	0.332
N60.9 Benign mammary dysplasia, unspecified	0.667	0.333
G91.9 Hydrocephalus, unspecified	0.666	0.333
M67.1 Other contracture of tendon (sheath)	0.666	0.334
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.664	0.336
B37 Candidiasis	0.664	0.336
M70 Soft tissue disorders related to use, overuse and pressure	0.664	0.336
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.664	0.336
K04.4 Acute apical periodontitis of pulpal origin	0.664	0.336
S82.1 Fracture of upper end of tibia	0.664	0.336
S40.0 Contusion of shoulder and upper arm	0.662	0.338
T90 Sequelae of injuries of head	0.661	0.339
N35.9 Urethral stricture, unspecified	0.661	0.339
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.661	0.339
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.661	0.339
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.661	0.339
M34.2 Systemic sclerosis induced by drugs and chemicals	0.660	0.340
M34.0 Progressive systemic sclerosis	0.660	0.340
M31.3 Wegener's granulomatosis	0.659	0.341
N75 Diseases of Bartholin's gland	0.659	0.341
T19 Foreign body in genito-urinary tract	0.658	0.341
T15 Foreign body on external eye	0.658	0.341
T16 Foreign body in ear	0.658	0.341
T98 Sequelae of other and unspecified effects of external causes	0.657	0.343
K09.2 Other cysts of jaw	0.656	0.344
H65.9 Nonsuppurative otitis media, unspecified	0.656	0.344
J00-J06 Acute upper respiratory infections	0.655	0.345
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.655	0.345
Q50-Q56 Congenital malformations of genital organs	0.654	0.346
K07 Dentofacial anomalies [including malocclusion]	0.654	0.346
S50 Superficial injury of forearm	0.653	0.347
H65.2 Chronic serous otitis media	0.653	0.347
N99.5 Malfunction of external stoma of urinary tract	0.652	0.348
M24.9 Joint derangement, unspecified	0.651	0.349
M24.8 Other specific joint derangements, not elsewhere classified	0.651	0.349
M24.7 Protrusio acetabuli	0.651	0.349
M24.6 Ankylosis of joint	0.651	0.349
M24.5 Contracture of joint	0.651	0.349
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.651	0.349
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.651	0.349
N63 Unspecified lump in breast	0.651	0.349
A80-A89 Viral infections of the central nervous system	0.650	0.350
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.650	0.350
Q20-Q28 Congenital malformations of the circulatory system	0.649	0.351
B90-B94 Sequelae of infectious and parasitic diseases	0.649	0.351
Q00-Q07 Congenital malformations of the nervous system	0.648	0.352
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.647	0.352
K41 Femoral hernia	0.647	0.353
S12 Fracture of neck	0.647	0.353
N41.9 Inflammatory disease of prostate, unspecified	0.647	0.353
J34.2 Deviated nasal septum	0.647	0.353
N60.4 Mammary duct ectasia	0.646	0.354
E40-E46 Malnutrition	0.646	0.354
J69 Pneumonitis due to solids and liquids	0.645	0.354
E06.5 Other chronic thyroiditis	0.645	0.355
E06.4 Drug-induced thyroiditis	0.645	0.355
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.645	0.355
E06.1 Subacute thyroiditis	0.645	0.355
E06.0 Acute thyroiditis	0.645	0.355
T91.8 Sequelae of other specified injuries of neck and trunk	0.644	0.356
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.644	0.356
G90.9 Disorder of autonomic nervous system, unspecified	0.643	0.357
J42 Unspecified chronic bronchitis	0.642	0.358
S20-S29 Injuries to the thorax	0.642	0.358
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.641	0.359
H90.5 Sensorineural hearing loss, unspecified	0.641	0.359
S82.10 Fracture of upper end of tibia (closed)	0.641	0.359
S69 Other and unspecified injuries of wrist and hand	0.640	0.360
G70-G73 Diseases of myoneural junction and muscle	0.640	0.360
K62.1 Rectal polyp	0.640	0.360
M40-M43 Deforming dorsopathies	0.639	0.361
T92 Sequelae of injuries of upper limb	0.639	0.361
M22.1 Recurrent subluxation of patella	0.638	0.361
M22.9 Disorder of patella, unspecified	0.638	0.361
M22.3 Other derangements of patella	0.638	0.361
M22.0 Recurrent dislocation of patella	0.638	0.361
M67.9 Disorder of synovium and tendon, unspecified	0.638	0.362
M67.4 Ganglion	0.638	0.362
M67.3 Transient synovitis	0.638	0.362
M67.2 Synovial hypertrophy, not elsewhere classified	0.638	0.362
M67.0 Short Achilles tendon (acquired)	0.638	0.362
K65-K67 Diseases of peritoneum	0.637	0.363
G90.3 Multisystem degeneration	0.636	0.364
K09.9 Cyst of oral region, unspecified	0.635	0.364
K09.1 Developmental (nonodontogenic) cysts of oral region	0.635	0.364
S67 Crushing injury of wrist and hand	0.634	0.366
K55.8 Other vascular disorders of intestine	0.634	0.366
N30.3 Trigonitis	0.632	0.367
T17 Foreign body in respiratory tract	0.632	0.368
J38.5 Laryngeal spasm	0.632	0.368
G96 Other disorders of central nervous system	0.632	0.368
S62.30 Fracture of other metacarpal bone (closed)	0.631	0.369
N64.8 Other specified disorders of breast	0.631	0.369
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.630	0.369
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.630	0.369
J35.2 Hypertrophy of adenoids	0.630	0.369
M65 Synovitis and tenosynovitis	0.630	0.370
E78.8 Other disorders of lipoprotein metabolism	0.630	0.370
G37 Other demyelinating diseases of central nervous system	0.630	0.370
K04.3 Abnormal hard tissue formation in pulp	0.629	0.371
K04.2 Pulp degeneration	0.629	0.371
K04.1 Necrosis of pulp	0.629	0.371
K04.0 Pulpitis	0.629	0.371
G99 Other disorders of nervous system in diseases classified elsewhere	0.629	0.371
N64.4 Mastodynia	0.629	0.371
N32.9 Bladder disorder, unspecified	0.628	0.372
K55.9 Vascular disorder of intestine, unspecified	0.626	0.374
S88 Traumatic amputation of lower leg	0.626	0.374
S87 Crushing injury of lower leg	0.626	0.374
S85 Injury of blood vessels at lower leg level	0.626	0.374
S84 Injury of nerves at lower leg level	0.626	0.374
S70 Superficial injury of hip and thigh	0.625	0.375
S46.0 Injury of tendon of the rotator cuff of shoulder	0.625	0.375
N32.4 Rupture of bladder, nontraumatic	0.623	0.377
N32.2 Vesical fistula, not elsewhere classified	0.623	0.377
T79 Certain early complications of trauma, not elsewhere classified	0.623	0.377
K46 Unspecified abdominal hernia	0.622	0.378
K14.8 Other diseases of tongue	0.622	0.378
T18.9 Foreign body in alimentary tract, part unspecified	0.621	0.378
T18.8 Foreign body in other and multiple parts of alimentary tract	0.621	0.378
T18.5 Foreign body in anus and rectum	0.621	0.378
T18.4 Foreign body in colon	0.621	0.378
T18.3 Foreign body in small intestine	0.621	0.378
T18.2 Foreign body in stomach	0.621	0.378
T18.0 Foreign body in mouth	0.621	0.378
K04.8 Radicular cyst	0.621	0.378
K52.1 Toxic gastro-enteritis and colitis	0.621	0.378
Chapter XX External causes of morbidity and mortality	0.621	0.379
T95 Sequelae of burns, corrosions and frostbite	0.620	0.379
T94 Sequelae of injuries involving multiple and unspecified body regions	0.620	0.379
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.620	0.379
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.620	0.379
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.620	0.379
M75.2 Bicipital tendinitis	0.620	0.380
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.620	0.380
Q35-Q37 Cleft lip and cleft palate	0.620	0.380
Q30-Q34 Congenital malformations of the respiratory system	0.620	0.380
G20-G26 Extrapyramidal and movement disorders	0.620	0.380
N70 Salpingitis and oophoritis	0.619	0.381
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.619	0.381
N61 Inflammatory disorders of breast	0.618	0.382
M20.3 Other deformity of hallux (acquired)	0.618	0.382
S80.1 Contusion of other and unspecified parts of lower leg	0.618	0.382
Q38-Q45 Other congenital malformations of the digestive system	0.617	0.383
M75.5 Bursitis of shoulder	0.617	0.383
K51.8 Other ulcerative colitis	0.616	0.384
M24.0 Loose body in joint	0.616	0.384
K51.4 Pseudopolyposis of colon	0.614	0.385
N76 Other inflammation of vagina and vulva	0.614	0.386
K14.6 Glossodynia	0.614	0.386
K14.5 Plicated tongue	0.614	0.386
K14.4 Atrophy of tongue papillae	0.614	0.386
K14.3 Hypertrophy of tongue papillae	0.614	0.386
K14.2 Median rhomboid glossitis	0.614	0.386
K14.1 Geographic tongue	0.614	0.386
K45 Other abdominal hernia	0.614	0.386
S80.9 Superficial injury of lower leg, unspecified	0.614	0.386
K52.3 Indeterminate colitis	0.614	0.386
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.612	0.388
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.612	0.388
S66.8 Injury of other muscles and tendons at wrist and hand level	0.612	0.388
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.612	0.388
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.612	0.388
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.612	0.388
S62.0 Fracture of navicular [scaphoid] bone of hand	0.611	0.388
H92.0 Otalgia	0.611	0.389
S81.9 Open wound of lower leg, part unspecified	0.611	0.389
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.611	0.389
N99.2 Postprocedural adhesions of vagina	0.611	0.389
N99.1 Postprocedural urethral stricture	0.611	0.389
A07 Other protozoal intestinal diseases	0.611	0.389
N50.9 Disorder of male genital organs, unspecified	0.610	0.390
N32.1 Vesicointestinal fistula	0.609	0.390
J38.6 Stenosis of larynx	0.608	0.392
S42.0 Fracture of clavicle	0.607	0.392
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.607	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations