TreeWAS – Variant ID: rs56201661

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000
D10-D36 Benign neoplasms	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
Chapter VI Diseases of the nervous system	0.999	0.001
C43-C44 Melanoma and other malignant neoplasms of skin	0.999	0.001
C67 Malignant neoplasm of bladder	0.999	0.001
C64-C68 Malignant neoplasms of urinary tract	0.999	0.001
M05-M14 Inflammatory polyarthropathies	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.998	0.002
D12.5 Sigmoid colon	0.997	0.003
M06 Other rheumatoid arthritis	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.996	0.004
C34 Malignant neoplasm of bronchus and lung	0.996	0.004
C44 Other malignant neoplasms of skin	0.996	0.004
C67.9 Bladder, unspecified	0.994	0.006
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.989	0.011
D37-D48 Neoplasms of uncertain or unknown behaviour	0.988	0.012
G80-G83 Cerebral palsy and other paralytic syndromes	0.988	0.012
Chapter XXI Factors influencing health status and contact with health services	0.985	0.015
M51 Other intervertebral disk disorders	0.984	0.016
C34.1 Upper lobe, bronchus or lung	0.983	0.017
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.982	0.018
G20-G26 Extrapyramidal and movement disorders	0.980	0.020
M54 Dorsalgia	0.979	0.021
M51.2 Other specified intervertebral disk displacement	0.979	0.021
G20 Parkinson's disease	0.972	0.028
D12.3 Transverse colon	0.964	0.036
M54.5 Low back pain	0.964	0.036
G82 Paraplegia and tetraplegia	0.959	0.041
Q60-Q64 Congenital malformations of the urinary system	0.959	0.041
S90-S99 Injuries to the ankle and foot	0.957	0.043
M50 Cervical disk disorders	0.950	0.050
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.947	0.053
Chapter V Mental and behavioural disorders	0.947	0.053
Chapter XIV Diseases of the genitourinary system	0.946	0.054
C43 Malignant melanoma of skin	0.945	0.055
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.944	0.056
D12.6 Colon, unspecified	0.944	0.056
C44.1 Skin of eyelid, including canthus	0.943	0.057
D00-D09 In situ neoplasms	0.940	0.060
Z85 Personal history of malignant neoplasm	0.938	0.062
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.938	0.062
Z00-Z13 Persons encountering health services for examination and investigation	0.938	0.062
N80-N98 Noninflammatory disorders of female genital tract	0.938	0.062
C44.7 Skin of lower limb, including hip	0.935	0.065
G83 Other paralytic syndromes	0.935	0.065
Z85.5 Personal history of malignant neoplasm of urinary tract	0.934	0.066
N84 Polyp of female genital tract	0.933	0.067
C44.6 Skin of upper limb, including shoulder	0.933	0.067
M86-M90 Other osteopathies	0.932	0.068
N84.0 Polyp of corpus uteri	0.931	0.069
M54.56 Low back pain (Lumbar region)	0.928	0.072
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.926	0.074
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.922	0.078
G00-G09 Inflammatory diseases of the central nervous system	0.922	0.078
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.922	0.078
C44.5 Skin of trunk	0.922	0.078
N81 Female genital prolapse	0.921	0.079
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.921	0.079
C43.5 Malignant melanoma of trunk	0.920	0.080
S20-S29 Injuries to the thorax	0.917	0.083
S10-S19 Injuries to the neck	0.915	0.085
C67.2 Lateral wall of bladder	0.915	0.085
C67.3 Anterior wall of bladder	0.913	0.087
G82.2 Paraplegia, unspecified	0.911	0.089
C34.9 Bronchus or lung, unspecified	0.910	0.090
Q61 Cystic kidney disease	0.906	0.094
F17 Mental and behavioural disorders due to use of tobacco	0.906	0.094
T91 Sequelae of injuries of neck and trunk	0.905	0.095
Z08 Follow-up examination after treatment for malignant neoplasm	0.905	0.095
T20-T25 Burns and corrosions of external body surface, specified by site	0.903	0.097
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.903	0.097
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.900	0.100
D29 Benign neoplasm of male genital organs	0.898	0.102
D12.8 Rectum	0.898	0.102
D07 Carcinoma in situ of other and unspecified genital organs	0.897	0.103
F17.2 Dependence syndrome	0.897	0.103
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.894	0.106
D13.1 Stomach	0.893	0.107
Z86 Personal history of certain other diseases	0.892	0.108
G90-G99 Other disorders of the nervous system	0.891	0.109
M50.1 Cervical disk disorder with radiculopathy	0.889	0.111
N40-N51 Diseases of male genital organs	0.888	0.112
Z97 Presence of other devices	0.885	0.115
Z86.4 Personal history of psychoactive substance abuse	0.884	0.116
D12.0 Caecum	0.884	0.116
S92 Fracture of foot, except ankle	0.883	0.117
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.883	0.117
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.879	0.121
M60-M63 Disorders of muscles	0.878	0.122
N81.6 Rectocele	0.871	0.129
N81.4 Uterovaginal prolapse, unspecified	0.870	0.130
D07.5 Prostate	0.868	0.132
D04 Carcinoma in situ of skin	0.867	0.133
N81.5 Vaginal enterocele	0.867	0.133
C67.6 Ureteric orifice	0.864	0.136
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.863	0.137
S22 Fracture of rib(s), sternum and thoracic spine	0.860	0.140
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.858	0.142
G83.4 Cauda equina syndrome	0.857	0.143
M06.3 Rheumatoid nodule	0.857	0.143
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.857	0.143
D34 Benign neoplasm of thyroid gland	0.856	0.144
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.855	0.145
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.854	0.146
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.853	0.147
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.851	0.149
N42 Other disorders of prostate	0.850	0.150
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.850	0.150
F99-F99 Unspecified mental disorder	0.849	0.151
T94 Sequelae of injuries involving multiple and unspecified body regions	0.848	0.152
M06.98 Rheumatoid arthritis, unspecified (Other)	0.847	0.153
S91 Open wound of ankle and foot	0.847	0.153
G70-G73 Diseases of myoneural junction and muscle	0.846	0.154
Q20-Q28 Congenital malformations of the circulatory system	0.846	0.154
M50.0 Cervical disk disorder with myelopathy	0.845	0.155
M05 Seropositive rheumatoid arthritis	0.845	0.155
G04 Encephalitis, myelitis and encephalomyelitis	0.843	0.157
Z90 Acquired absence of organs, not elsewhere classified	0.842	0.158
Z90.7 Acquired absence of genital organ(s)	0.841	0.159
T90 Sequelae of injuries of head	0.841	0.159
M14 Arthropathies in other diseases classified elsewhere	0.841	0.159
Q50-Q56 Congenital malformations of genital organs	0.840	0.160
C34.0 Main bronchus	0.839	0.161
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.839	0.161
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.838	0.162
Q61.0 Congenital single renal cyst	0.837	0.163
C34.3 Lower lobe, bronchus or lung	0.829	0.171
M54.55 Low back pain (Thoracolumbar region)	0.829	0.171
D12.1 Appendix	0.827	0.173
Z80 Family history of malignant neoplasm	0.826	0.174
T79-T79 Certain early complications of trauma	0.824	0.176
G95 Other diseases of spinal cord	0.824	0.176
Z57 Occupational exposure to risk-factors	0.824	0.176
Z85.6 Personal history of leukaemia	0.823	0.177
Z09.0 Follow-up examination after surgery for other conditions	0.822	0.178
N48 Other disorders of penis	0.822	0.178
M88 Paget's disease of bone [osteitis deformans]	0.819	0.181
N93 Other abnormal uterine and vaginal bleeding	0.819	0.181
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.817	0.183
Q38-Q45 Other congenital malformations of the digestive system	0.817	0.183
M54.50 Low back pain (Multiple sites in spine)	0.817	0.183
M54.9 Dorsalgia, unspecified	0.816	0.184
S22.2 Fracture of sternum	0.812	0.188
M91-M94 Chondropathies	0.811	0.188
Z97.4 Presence of external hearing-aid	0.811	0.189
T91.3 Sequelae of injury of spinal cord	0.810	0.190
M40-M43 Deforming dorsopathies	0.810	0.190
M45-M49 Spondylopathies	0.809	0.191
Z63 Other problems related to primary support group, including family circumstances	0.807	0.193
N42.2 Atrophy of prostate	0.805	0.195
Z80.0 Family history of malignant neoplasm of digestive organs	0.802	0.198
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.801	0.199
T92 Sequelae of injuries of upper limb	0.800	0.200
D10 Benign neoplasm of mouth and pharynx	0.799	0.201
G82.5 Tetraplegia, unspecified	0.798	0.202
D46 Myelodysplastic syndromes	0.798	0.202
S92.0 Fracture of calcaneus	0.798	0.202
Z02 Examination and encounter for administrative purposes	0.797	0.203
D12.7 Rectosigmoid junction	0.796	0.204
Q64 Other congenital malformations of urinary system	0.793	0.207
S80-S89 Injuries to the knee and lower leg	0.793	0.207
D18 Haemangioma and lymphangioma, any site	0.791	0.209
F70-F79 Mental retardation	0.791	0.209
F10 Mental and behavioural disorders due to use of alcohol	0.788	0.212
D29.1 Prostate	0.788	0.212
M89 Other disorders of bone	0.787	0.213
N42.8 Other specified disorders of prostate	0.787	0.213
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.786	0.214
D22 Melanocytic naevi	0.784	0.216
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.783	0.216
S19 Other and unspecified injuries of neck	0.780	0.220
M62 Other disorders of muscle	0.780	0.220
Z01.6 Radiological examination, not elsewhere classified	0.779	0.221
F99 Mental disorder, not otherwise specified	0.779	0.221
M15-M19 Arthrosis	0.778	0.222
C67.4 Posterior wall of bladder	0.778	0.222
S22.20 Fracture of sternum (closed)	0.777	0.223
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.777	0.223
Z90.2 Acquired absence of lung [part of]	0.775	0.225
N47 Redundant prepuce, phimosis and paraphimosis	0.774	0.226
D45 Polycythaemia vera	0.773	0.226
C67.1 Dome of bladder	0.773	0.227
T98 Sequelae of other and unspecified effects of external causes	0.772	0.228
D13.0 Oesophagus	0.771	0.229
N84.3 Polyp of vulva	0.771	0.229
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.769	0.231
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.768	0.232
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.767	0.233
T91.1 Sequelae of fracture of spine	0.766	0.234
M19 Other arthrosis	0.766	0.234
M54.4 Lumbago with sciatica	0.766	0.234
C43.2 Malignant melanoma of ear and external auricular canal	0.765	0.235
Q61.3 Polycystic kidney, unspecified	0.765	0.235
G91 Hydrocephalus	0.765	0.235
D38.1 Trachea, bronchus and lung	0.763	0.237
Q60 Renal agenesis and other reduction defects of kidney	0.762	0.238
Z91 Personal history of risk-factors, not elsewhere classified	0.760	0.240
D04.3 Skin of other and unspecified parts of face	0.760	0.240
Z87 Personal history of other diseases and conditions	0.760	0.240
M19.9 Arthrosis, unspecified	0.759	0.241
G82.1 Spastic paraplegia	0.759	0.241
D32 Benign neoplasm of meninges	0.758	0.242
M06.34 Rheumatoid nodule (Hand)	0.757	0.243
M54.8 Other dorsalgia	0.757	0.243
M19.90 Arthrosis, unspecified (Multiple sites)	0.757	0.243
D39.1 Ovary	0.756	0.243
Z97.5 Presence of (intra-uterine) contraceptive device	0.756	0.244
N00-N08 Glomerular diseases	0.756	0.244
Z98 Other postsurgical states	0.756	0.244
M11 Other crystal arthropathies	0.752	0.248
T94.1 Sequelae of injuries, not specified by body region	0.752	0.248
C67.0 Trigone of bladder	0.751	0.249
D43.2 Brain, unspecified	0.750	0.250
Z86.0 Personal history of other neoplasms	0.749	0.251
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.748	0.252
M96.0 Pseudarthrosis after fusion or arthrodesis	0.748	0.252
M54.59 Low back pain (Site unspecified)	0.748	0.252
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.746	0.254
S91.1 Open wound of toe(s) without damage to nail	0.746	0.254
D33 Benign neoplasm of brain and other parts of central nervous system	0.743	0.257
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.743	0.257
M88.9 Paget's disease of bone, unspecified	0.739	0.261
G50-G59 Nerve, nerve root and plexus disorders	0.739	0.261
C34.2 Middle lobe, bronchus or lung	0.738	0.262
D26 Other benign neoplasms of uterus	0.738	0.262
S40-S49 Injuries to the shoulder and upper arm	0.737	0.263
S92.00 Fracture of calcaneus (closed)	0.737	0.263
Z63.8 Other specified problems related to primary support group	0.736	0.264
N48.6 Balanitis xerotica obliterans	0.736	0.264
S96 Injury of muscle and tendon at ankle and foot level	0.736	0.264
M86 Osteomyelitis	0.736	0.264
M05.9 Seropositive rheumatoid arthritis, unspecified	0.735	0.265
D12.9 Anus and anal canal	0.735	0.265
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.734	0.265
N85 Other noninflammatory disorders of uterus, except cervix	0.734	0.266
G83.1 Monoplegia of lower limb	0.734	0.266
Z40-Z54 Persons encountering health services for specific procedures and health care	0.732	0.268
C67.5 Bladder neck	0.731	0.269
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.730	0.270
D29.4 Scrotum	0.729	0.271
D27 Benign neoplasm of ovary	0.728	0.272
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.728	0.272
D43.0 Brain, supratentorial	0.728	0.272
M14.6 Neuropathic arthropathy	0.728	0.272
S37 Injury of urinary and pelvic organs	0.727	0.273
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.727	0.273
D04.6 Skin of upper limb, including shoulder	0.727	0.273
M07 Psoriatic and enteropathic arthropathies	0.726	0.274
D47.2 Monoclonal gammopathy	0.726	0.274
T23 Burn and corrosion of wrist and hand	0.725	0.275
Z09.7 Follow-up examination after combined treatment for other conditions	0.725	0.275
S10 Superficial injury of neck	0.725	0.275
M65-M68 Disorders of synovium and tendon	0.725	0.275
G83.9 Paralytic syndrome, unspecified	0.724	0.276
Z85.9 Personal history of malignant neoplasm, unspecified	0.724	0.276
T14 Injury of unspecified body region	0.723	0.277
S14 Injury of nerves and spinal cord at neck level	0.723	0.277
M80-M85 Disorders of bone density and structure	0.723	0.277
S92.4 Fracture of great toe	0.723	0.277
Q51 Congenital malformations of uterus and cervix	0.722	0.278
S27 Injury of other and unspecified intrathoracic organs	0.722	0.278
G83.8 Other specified paralytic syndromes	0.718	0.282
D31 Benign neoplasm of eye and adnexa	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.717	0.283
D19 Benign neoplasm of mesothelial tissue	0.717	0.283
C67.8 Overlapping lesion of bladder	0.716	0.284
C67.7 Urachus	0.716	0.284
C68 Malignant neoplasm of other and unspecified urinary organs	0.716	0.284
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.716	0.284
M12 Other specific arthropathies	0.716	0.284
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284
M08 Juvenile arthritis	0.716	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.715	0.285
C38 Malignant neoplasm of heart, mediastinum and pleura	0.715	0.285
C31 Malignant neoplasm of accessory sinuses	0.715	0.285
C30 Malignant neoplasm of nasal cavity and middle ear	0.715	0.285
C37 Malignant neoplasm of thymus	0.715	0.285
C33 Malignant neoplasm of trachea	0.715	0.285
D04.5 Skin of trunk	0.715	0.285
M06.8 Other specified rheumatoid arthritis	0.715	0.285
M06.2 Rheumatoid bursitis	0.715	0.285
M06.1 Adult-onset Still's disease	0.715	0.285
C34.8 Overlapping lesion of bronchus and lung	0.714	0.286
C44.8 Overlapping lesion of skin	0.714	0.286
M48 Other spondylopathies	0.713	0.287
C32 Malignant neoplasm of larynx	0.713	0.287
N83.0 Follicular cyst of ovary	0.713	0.287
Q63 Other congenital malformations of kidney	0.713	0.287
N83.1 Corpus luteum cyst	0.711	0.289
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.711	0.289
M00-M03 Infectious arthropathies	0.710	0.290
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.709	0.291
Q35-Q37 Cleft lip and cleft palate	0.709	0.291
Q30-Q34 Congenital malformations of the respiratory system	0.709	0.291
G95.1 Vascular myelopathies	0.709	0.291
S92.7 Multiple fractures of foot	0.709	0.291
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.708	0.292
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.708	0.292
M19.97 Arthrosis, unspecified (Ankle and foot)	0.708	0.292
M54.6 Pain in thoracic spine	0.707	0.293
M51.3 Other specified intervertebral disk degeneration	0.705	0.295
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.705	0.295
M51.4 Schmorl's nodes	0.705	0.295
Z57.5 Occupational exposure to toxic agents in other industries	0.705	0.295
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.705	0.295
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.705	0.295
M50.3 Other cervical disk degeneration	0.705	0.295
N83.3 Acquired atrophy of ovary and Fallopian tube	0.704	0.296
T95 Sequelae of burns, corrosions and frostbite	0.704	0.296
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.704	0.296
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.704	0.296
D02 Carcinoma in situ of middle ear and respiratory system	0.704	0.296
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.704	0.296
N25-N29 Other disorders of kidney and ureter	0.704	0.296
Q23 Congenital malformations of aortic and mitral valves	0.703	0.297
S21 Open wound of thorax	0.703	0.297
T92.9 Sequelae of unspecified injury of upper limb	0.703	0.297
G23 Other degenerative diseases of basal ganglia	0.702	0.298
G21 Secondary Parkinsonism	0.702	0.298
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.702	0.298
G22 Parkinsonism in diseases classified elsewhere	0.702	0.298
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.702	0.298
M54.0 Panniculitis affecting regions of neck and back	0.702	0.298
C51-C58 Malignant neoplasms of female genital organs	0.701	0.299
T79 Certain early complications of trauma, not elsewhere classified	0.700	0.300
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.699	0.301
G82.4 Spastic tetraplegia	0.698	0.301
N93.8 Other specified abnormal uterine and vaginal bleeding	0.698	0.302
N30-N39 Other diseases of urinary system	0.698	0.302
G95.9 Disease of spinal cord, unspecified	0.697	0.303
T21 Burn and corrosion of trunk	0.696	0.304
Z02.8 Other examinations for administrative purposes	0.695	0.305
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.695	0.305
D22.4 Melanocytic naevi of scalp and neck	0.694	0.306
T90.8 Sequelae of other specified injuries of head	0.694	0.306
Q25 Congenital malformations of great arteries	0.693	0.307
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.693	0.307
S11 Open wound of neck	0.693	0.307
N95 Menopausal and other perimenopausal disorders	0.693	0.307
M54.54 Low back pain-Thoracic	0.691	0.309
M54.53 Low back pain-Cervicothoracic	0.691	0.309
M54.52 Low back pain-Cervical	0.691	0.309
M54.51 Low back pain-Occipit-atl-axl	0.691	0.309
S36 Injury of intra-abdominal organs	0.691	0.309
G99 Other disorders of nervous system in diseases classified elsewhere	0.691	0.309
D28 Benign neoplasm of other and unspecified female genital organs	0.690	0.310
Z93 Artificial opening status	0.690	0.310
D11 Benign neoplasm of major salivary glands	0.690	0.310
N91 Absent, scanty and rare menstruation	0.689	0.311
M62.8 Other specified disorders of muscle	0.689	0.311
Q80-Q89 Other congenital malformations	0.689	0.311
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.689	0.311
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.688	0.311
G82.3 Flaccid tetraplegia	0.688	0.312
G82.0 Flaccid paraplegia	0.688	0.312
T90.5 Sequelae of intracranial injury	0.688	0.312
D13.2 Duodenum	0.688	0.312
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.688	0.312
Z97.3 Presence of spectacles and contact lenses	0.688	0.312
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.688	0.312
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.687	0.313
S31 Open wound of abdomen, lower back and pelvis	0.687	0.313
N46 Male infertility	0.687	0.313
N08 Glomerular disorders in diseases classified elsewhere	0.687	0.313
N48.9 Disorder of penis, unspecified	0.687	0.313
D41.4 Bladder	0.687	0.313
F10.3 Withdrawal state	0.686	0.313
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.686	0.314
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.686	0.314
S98 Traumatic amputation of ankle and foot	0.686	0.314
S97 Crushing injury of ankle and foot	0.686	0.314
S95 Injury of blood vessels at ankle and foot level	0.686	0.314
S94 Injury of nerves at ankle and foot level	0.686	0.314
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.685	0.315
F10.2 Dependence syndrome	0.685	0.315
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.685	0.315
S12 Fracture of neck	0.684	0.315
S99 Other and unspecified injuries of ankle and foot	0.684	0.316
G24 Dystonia	0.684	0.316
N82 Fistulae involving female genital tract	0.684	0.316
N97 Female infertility	0.684	0.316
S19.9 Unspecified injury of neck	0.683	0.317
M50.9 Cervical disk disorder, unspecified	0.681	0.319
M50.8 Other cervical disk disorders	0.681	0.319
G71 Primary disorders of muscles	0.681	0.319
D35 Benign neoplasm of other and unspecified endocrine glands	0.680	0.320
Z97.1 Presence of artificial limb (complete)(partial)	0.680	0.320
G72 Other myopathies	0.680	0.320
M54.1 Radiculopathy	0.680	0.320
Z87.0 Personal history of diseases of the respiratory system	0.679	0.321
D13.9 Ill-defined sites within the digestive system	0.679	0.321
D13.7 Endocrine pancreas	0.679	0.321
D13.6 Pancreas	0.679	0.321
D13.4 Liver	0.679	0.321
D13.3 Other and unspecified parts of small intestine	0.679	0.321
T13 Other injuries of lower limb, level unspecified	0.679	0.321
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.679	0.321
M94 Other disorders of cartilage	0.679	0.321
F79 Unspecified mental retardation	0.679	0.321
M43 Other deforming dorsopathies	0.679	0.321
Z57.2 Occupational exposure to dust	0.679	0.321
C43.8 Overlapping malignant melanoma of skin	0.678	0.322
C43.1 Malignant melanoma of eyelid, including canthus	0.678	0.322
C43.0 Malignant melanoma of lip	0.678	0.322
F80-F89 Disorders of psychological development	0.678	0.322
M90 Osteopathies in diseases classified elsewhere	0.677	0.323
N48.1 Balanoposthitis	0.677	0.323
S30 Superficial injury of abdomen, lower back and pelvis	0.676	0.324
C79 Secondary malignant neoplasm of other sites	0.676	0.324
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.675	0.325
Z56 Problems related to employment and unemployment	0.675	0.325
G06 Intracranial and intraspinal abscess and granuloma	0.674	0.326
D01 Carcinoma in situ of other and unspecified digestive organs	0.674	0.326
Z09.4 Follow-up examination after treatment of fracture	0.674	0.326
Q64.7 Other congenital malformations of bladder and urethra	0.674	0.326
D47.3 Essential (haemorrhagic) thrombocythaemia	0.673	0.327
G80 Infantile cerebral palsy	0.673	0.327
Z85.0 Personal history of malignant neoplasm of digestive organs	0.673	0.327
Z10 Routine general health check-up of defined subpopulation	0.673	0.327
N98 Complications associated with artificial fertilisation	0.672	0.327
N96 Habitual aborter	0.672	0.327
T91.2 Sequelae of other fracture of thorax and pelvis	0.672	0.328
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.672	0.328
Z64 Problems related to certain psychosocial circumstances	0.672	0.328
F10.5 Psychotic disorder	0.671	0.329
G83.5 Locked-in syndrome	0.670	0.330
G83.3 Monoplegia, unspecified	0.670	0.330
G83.2 Monoplegia of upper limb	0.670	0.330
G83.0 Diplegia of upper limbs	0.670	0.330
S22.0 Fracture of thoracic vertebra	0.670	0.330
Z13 Special screening examination for other diseases and disorders	0.670	0.330
Z47 Other orthopaedic follow-up care	0.670	0.330
C65 Malignant neoplasm of renal pelvis	0.669	0.331
C44.9 Malignant neoplasm of skin, unspecified	0.669	0.331
C43.3 Malignant melanoma of other and unspecified parts of face	0.669	0.331
N84.9 Polyp of female genital tract, unspecified	0.669	0.331
N84.8 Polyp of other parts of female genital tract	0.669	0.331
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.669	0.331
D41.0 Kidney	0.668	0.332
S92.5 Fracture of other toe	0.666	0.334
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.666	0.334
S81 Open wound of lower leg	0.665	0.335
M19.98 Arthrosis, unspecified (Other)	0.665	0.335
M89.0 Algoneurodystrophy	0.665	0.335
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.664	0.336
S29 Other and unspecified injuries of thorax	0.664	0.336
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.664	0.336
F18 Mental and behavioural disorders due to use of volatile solvents	0.664	0.336
F16 Mental and behavioural disorders due to use of hallucinogens	0.664	0.336
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.664	0.336
F14 Mental and behavioural disorders due to use of cocaine	0.664	0.336
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.664	0.336
N81.8 Other female genital prolapse	0.664	0.336
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.663	0.336
T91.9 Sequelae of unspecified injury of neck and trunk	0.663	0.337
D46.9 Myelodysplastic syndrome, unspecified	0.662	0.338
D09 Carcinoma in situ of other and unspecified sites	0.662	0.338
S91.3 Open wound of other parts of foot	0.661	0.339
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.661	0.339
G00 Bacterial meningitis, not elsewhere classified	0.661	0.339
G09 Sequelae of inflammatory diseases of central nervous system	0.661	0.339
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.661	0.339
G01 Meningitis in bacterial diseases classified elsewhere	0.661	0.339
Z65 Problems related to other psychosocial circumstances	0.661	0.339
Z62 Other problems related to upbringing	0.661	0.339
Z61 Problems related to negative life events in childhood	0.661	0.339
Z59 Problems related to housing and economic circumstances	0.661	0.339
Z55 Problems related to education and literacy	0.661	0.339
Q21 Congenital malformations of cardiac septa	0.661	0.339
M51.8 Other specified intervertebral disk disorders	0.661	0.339
S92.2 Fracture of other tarsal bone(s)	0.660	0.340
F25 Schizoaffective disorders	0.659	0.341
D22.1 Melanocytic naevi of eyelid, including canthus	0.659	0.341
C44.4 Skin of scalp and neck	0.658	0.342
Z97.0 Presence of artificial eye	0.658	0.342
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.658	0.342
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.658	0.342
S26 Injury of heart	0.658	0.342
S25 Injury of blood vessels of thorax	0.658	0.342
S24 Injury of nerves and spinal cord at thorax level	0.658	0.342
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.658	0.342
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.658	0.342
G57 Mononeuropathies of lower limb	0.658	0.342
Q54 Hypospadias	0.657	0.343
D13.5 Extrahepatic bile ducts	0.657	0.343
C43.9 Malignant melanoma of skin, unspecified	0.657	0.343
S17 Crushing injury of neck	0.656	0.344
S15 Injury of blood vessels at neck level	0.656	0.344
S18 Traumatic amputation at neck level	0.656	0.344
S16 Injury of muscle and tendon at neck level	0.656	0.344

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations