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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56319538
log Bayes Factor = 14.9989
Chromosome 3   position 78,406,226  (GRCh37) Explore rs56319538 on Ensembl!
Variant rs56319538 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I50 Heart failure
0.995 0.005 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.992 0.008 0.000
Z46 Fitting and adjustment of other devices
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
I50.1 Left ventricular failure
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
Z46.6 Fitting and adjustment of urinary device
0.980 0.020 0.000
D50-D53 Nutritional anaemias
0.977 0.023 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.976 0.024 0.000
I47 Paroxysmal tachycardia
0.970 0.030 0.000
L82 Seborrhoeic keratosis
0.968 0.032 0.000
Chapter X Diseases of the respiratory system
0.967 0.033 0.000
L90 Atrophic disorders of skin
0.967 0.033 0.000
Z51 Other medical care
0.957 0.043 0.000
D50 Iron deficiency anaemia
0.954 0.046 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.951 0.049 0.000
L90.5 Scar conditions and fibrosis of skin
0.950 0.050 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.947 0.053 0.000
J30-J39 Other diseases of upper respiratory tract
0.940 0.060 0.000
Chapter I Certain infectious and parasitic diseases
0.939 0.061 0.000
Z13 Special screening examination for other diseases and disorders
0.939 0.061 0.000
I47.1 Supraventricular tachycardia
0.937 0.063 0.000
M50-M54 Other dorsopathies
0.936 0.064 0.000
I50.0 Congestive heart failure
0.932 0.068 0.000
Chapter VII Diseases of the eye and adnexa
0.927 0.073 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.926 0.074 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.925 0.075 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.923 0.077 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.923 0.077 0.000
J34 Other disorders of nose and nasal sinuses
0.919 0.081 0.000
Chapter XIV Diseases of the genitourinary system
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
J09-J18 Influenza and pneumonia
0.915 0.085 0.000
D50.8 Other iron deficiency anaemias
0.913 0.087 0.000
L60-L75 Disorders of skin appendages
0.909 0.091 0.000
G90-G99 Other disorders of the nervous system
0.909 0.091 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.906 0.094 0.000
I51 Complications and ill-defined descriptions of heart disease
0.905 0.095 0.000
J34.2 Deviated nasal septum
0.902 0.098 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.893 0.107 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.887 0.113 0.000
N10-N16 Renal tubulo-interstitial diseases
0.884 0.116 0.000
J18 Pneumonia, organism unspecified
0.882 0.118 0.000
Chapter VIII Diseases of the ear and mastoid process
0.881 0.119 0.000
B95-B98 Bacterial, viral and other infectious agents
0.880 0.120 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.879 0.121 0.000
D68 Other coagulation defects
0.879 0.121 0.000
D50.9 Iron deficiency anaemia, unspecified
0.878 0.122 0.000
G20-G26 Extrapyramidal and movement disorders
0.877 0.123 0.000
Z60 Problems related to social environment
0.872 0.128 0.000
M51 Other intervertebral disk disorders
0.868 0.132 0.000
Z03.3 Observation for suspected nervous system disorder
0.866 0.134 0.000
N73 Other female pelvic inflammatory diseases
0.864 0.136 0.000
E70-E90 Metabolic disorders
0.859 0.141 0.000
Z51.3 Blood transfusion without reported diagnosis
0.858 0.142 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.856 0.144 0.000
E50-E64 Other nutritional deficiencies
0.856 0.144 0.000
J18.1 Lobar pneumonia, unspecified
0.854 0.146 0.000
I20-I25 Ischaemic heart diseases
0.854 0.146 0.000
W00-W19 Falls
0.854 0.146 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.853 0.147 0.000
N73.6 Female pelvic peritoneal adhesions
0.852 0.148 0.000
L50-L54 Urticaria and erythema
0.852 0.148 0.000
N13 Obstructive and reflux uropathy
0.850 0.150 0.000
I60-I69 Cerebrovascular diseases
0.849 0.151 0.000
Chapter V Mental and behavioural disorders
0.847 0.153 0.000
D51 Vitamin B12 deficiency anaemia
0.844 0.156 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.836 0.164 0.000
Z60.2 Living alone
0.836 0.164 0.000
Z51.1 Chemotherapy session for neoplasm
0.835 0.165 0.000
H53-H54 Visual disturbances and blindness
0.831 0.169 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.829 0.171 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.827 0.173 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.826 0.174 0.000
M54 Dorsalgia
0.825 0.175 0.000
Y43 Primarily systemic agents
0.824 0.176 0.000
L81 Other disorders of pigmentation
0.824 0.176 0.000
Z46.8 Fitting and adjustment of other specified devices
0.823 0.177 0.000
H90-H95 Other disorders of ear
0.822 0.178 0.000
Z51.5 Palliative care
0.821 0.179 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.820 0.180 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.818 0.182 0.000
M70-M79 Other soft tissue disorders
0.817 0.183 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.816 0.184 0.000
M51.2 Other specified intervertebral disk displacement
0.815 0.185 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.815 0.185 0.000
I46 Cardiac arrest
0.814 0.186 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.814 0.186 0.000
Z53.9 Procedure not carried out, unspecified reason
0.812 0.188 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.809 0.191 0.000
J30 Vasomotor and allergic rhinitis
0.809 0.191 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.808 0.192 0.000
M65-M68 Disorders of synovium and tendon
0.807 0.193 0.000
L60 Nail disorders
0.804 0.196 0.000
N99-N99 Other disorders of the genitourinary system
0.803 0.197 0.000
I51.9 Heart disease, unspecified
0.802 0.198 0.000
Z03.4 Observation for suspected myocardial infarction
0.802 0.198 0.000
Z40 Prophylactic surgery
0.801 0.199 0.000
Z41 Procedures for purposes other than remedying health state
0.801 0.199 0.000
Y57 Other and unspecified drugs and medicaments
0.799 0.201 0.000
G93 Other disorders of brain
0.798 0.202 0.000
I47.2 Ventricular tachycardia
0.797 0.203 0.000
E10-E14 Diabetes mellitus
0.797 0.203 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.797 0.203 0.000
Z02 Examination and encounter for administrative purposes
0.796 0.204 0.000
G30-G32 Other degenerative diseases of the nervous system
0.795 0.205 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.795 0.205 0.000
D68.9 Coagulation defect, unspecified
0.794 0.206 0.000
M20-M25 Other joint disorders
0.794 0.206 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.789 0.211 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.789 0.211 0.000
I20 Angina pectoris
0.785 0.215 0.000
I51.8 Other ill-defined heart diseases
0.785 0.215 0.000
M45-M49 Spondylopathies
0.784 0.216 0.000
Y45.0 Opioids and related analgesics
0.782 0.218 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.781 0.219 0.000
Z04 Examination and observation for other reasons
0.781 0.219 0.000
J34.3 Hypertrophy of nasal turbinates
0.780 0.220 0.000
Z43 Attention to artificial openings
0.779 0.221 0.000
H53 Visual disturbances
0.777 0.223 0.000
H30-H36 Disorders of choroid and retina
0.777 0.223 0.000
I50.9 Heart failure, unspecified
0.776 0.224 0.000
G24 Dystonia
0.773 0.227 0.000
Z53.0 Procedure not carried out because of contraindication
0.773 0.227 0.000
E87.2 Acidosis
0.769 0.231 0.000
I36 Nonrheumatic tricuspid valve disorders
0.768 0.232 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.768 0.232 0.000
M53 Other dorsopathies, not elsewhere classified
0.767 0.233 0.000
Z00.0 General medical examination
0.767 0.233 0.000
E53 Deficiency of other B group vitamins
0.766 0.234 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.765 0.235 0.000
E20-E35 Disorders of other endocrine glands
0.764 0.236 0.000
D80-D89 Certain disorders involving the immune mechanism
0.762 0.238 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.762 0.238 0.000
V20-V29 Motorcycle rider injured in transport accident
0.761 0.238 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.761 0.239 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.761 0.239 0.000
D68.2 Hereditary deficiency of other clotting factors
0.760 0.240 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.759 0.241 0.000
Z54 Convalescence
0.756 0.244 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.755 0.245 0.000
L20-L30 Dermatitis and eczema
0.755 0.245 0.000
F30-F39 Mood [affective] disorders
0.752 0.248 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.249 0.000
Q50-Q56 Congenital malformations of genital organs
0.750 0.250 0.000
N00-N08 Glomerular diseases
0.750 0.250 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.749 0.251 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.749 0.251 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.749 0.251 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.747 0.253 0.000
H43-H45 Disorders of vitreous body and globe
0.746 0.254 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.746 0.254 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
M54.5 Low back pain
0.743 0.256 0.000
I85 Oesophageal varices
0.742 0.258 0.000
Y45.2 Propionic acid derivatives
0.742 0.258 0.000
I30 Acute pericarditis
0.741 0.259 0.000
Z01.8 Other specified special examinations
0.740 0.260 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.739 0.261 0.000
N13.4 Hydroureter
0.739 0.261 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.739 0.261 0.000
D55-D59 Haemolytic anaemias
0.738 0.261 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.738 0.262 0.000
Z03.8 Observation for other suspected diseases and conditions
0.736 0.264 0.000
Y44 Agents primarily affecting blood constituents
0.734 0.266 0.000
Z03.1 Observation for suspected malignant neoplasm
0.734 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.734 0.266 0.000
Z47 Other orthopaedic follow-up care
0.734 0.266 0.000
G91 Hydrocephalus
0.733 0.267 0.000
I42 Cardiomyopathy
0.732 0.268 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
A30-A49 Other bacterial diseases
0.732 0.268 0.000
N20-N23 Urolithiasis
0.732 0.268 0.000
N13.3 Other and unspecified hydronephrosis
0.731 0.269 0.000
Chapter XI Diseases of the digestive system
0.730 0.270 0.000
I63 Cerebral infarction
0.730 0.270 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.729 0.271 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.728 0.272 0.000
I44 Atrioventricular and left bundle-branch block
0.727 0.273 0.000
J20-J22 Other acute lower respiratory infections
0.727 0.273 0.000
W13 Fall from, out of or through building or structure
0.727 0.273 0.000
N76 Other inflammation of vagina and vulva
0.726 0.273 0.000
I20.0 Unstable angina
0.726 0.274 0.000
Z45 Adjustment and management of implanted device
0.726 0.274 0.000
Z51.9 Medical care, unspecified
0.724 0.276 0.000
M91-M94 Chondropathies
0.724 0.276 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.723 0.277 0.000
G61 Inflammatory polyneuropathy
0.723 0.277 0.000
J39 Other diseases of upper respiratory tract
0.722 0.278 0.000
J11 Influenza, virus not identified
0.722 0.278 0.000
W20-W49 Exposure to inanimate mechanical forces
0.721 0.279 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.721 0.279 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.719 0.281 0.000
N10 Acute tubulo-interstitial nephritis
0.719 0.281 0.000
J32 Chronic sinusitis
0.719 0.281 0.000
B99-B99 Other infectious diseases
0.717 0.282 0.000
I27 Other pulmonary heart diseases
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G93.3 Postviral fatigue syndrome
0.717 0.283 0.000
Chapter II Neoplasms
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
Z13.5 Special screening examination for eye and ear disorders
0.716 0.284 0.000
G90 Disorders of autonomic nervous system
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
M54.56 Low back pain (Lumbar region)
0.716 0.284 0.000
H53.2 Diplopia
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
Y40 Systemic antibiotics
0.712 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.712 0.288 0.000
L50 Urticaria
0.711 0.289 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.711 0.289 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.711 0.289 0.000
L94 Other localised connective tissue disorders
0.711 0.289 0.000
L93 Lupus erythematosus
0.711 0.289 0.000
L87 Transepidermal elimination disorders
0.711 0.289 0.000
L88 Pyoderma gangrenosum
0.711 0.289 0.000
L86 Keratoderma in diseases classified elsewhere
0.711 0.289 0.000
L83 Acanthosis nigricans
0.711 0.289 0.000
L80 Vitiligo
0.711 0.289 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.711 0.289 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.711 0.289 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.711 0.289 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.711 0.289 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.711 0.289 0.000
Z46.1 Fitting and adjustment of hearing aid
0.711 0.289 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.710 0.290 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.710 0.290 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.709 0.291 0.000
I33 Acute and subacute endocarditis
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
H93 Other disorders of ear, not elsewhere classified
0.708 0.292 0.000
S50-S59 Injuries to the elbow and forearm
0.706 0.294 0.000
H40-H42 Glaucoma
0.704 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.296 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.704 0.296 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.703 0.297 0.000
E53.8 Deficiency of other specified B group vitamins
0.702 0.298 0.000
Q60-Q64 Congenital malformations of the urinary system
0.702 0.298 0.000
V10-V19 Pedal cyclist injured in transport accident
0.702 0.298 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.701 0.299 0.000
D53 Other nutritional anaemias
0.700 0.300 0.000
D52 Folate deficiency anaemia
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
Z04.8 Examination and observation for other specified reasons
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
Y43.3 Other antineoplastic drugs
0.700 0.300 0.000
M80-M85 Disorders of bone density and structure
0.698 0.302 0.000
Y95 Nosocomial condition
0.697 0.303 0.000
H60-H62 Diseases of external ear
0.697 0.303 0.000
L08 Other local infections of skin and subcutaneous tissue
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
Q80-Q89 Other congenital malformations
0.696 0.304 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.695 0.305 0.000
I47.0 Reentry ventricular arrhythmia
0.695 0.305 0.000
Y57.5 X-ray contrast media
0.695 0.305 0.000
Y54.5 Other diuretics
0.695 0.305 0.000
L90.9 Atrophic disorder of skin, unspecified
0.693 0.307 0.000
L90.8 Other atrophic disorders of skin
0.693 0.307 0.000
L90.6 Striae atrophicae
0.693 0.307 0.000
L90.4 Acrodermatitis chronica atrophicans
0.693 0.307 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.693 0.307 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.693 0.307 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.693 0.307 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.693 0.307 0.000
L85 Other epidermal thickening
0.692 0.308 0.000
E78.2 Mixed hyperlipidaemia
0.692 0.308 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.692 0.308 0.000
Y45.1 Salicylates
0.692 0.308 0.000
G25 Other extrapyramidal and movement disorders
0.691 0.309 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.690 0.310 0.000
Z63 Other problems related to primary support group, including family circumstances
0.689 0.311 0.000
L89 Decubitus ulcer
0.689 0.311 0.000
M05-M14 Inflammatory polyarthropathies
0.689 0.311 0.000
I62 Other nontraumatic intracranial haemorrhage
0.688 0.312 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.687 0.313 0.000
Z51.6 Desensitisation to allergens
0.686 0.314 0.000
L60.0 Ingrowing nail
0.685 0.315 0.000
G62 Other polyneuropathies
0.684 0.316 0.000
D50.1 Sideropenic dysphagia
0.684 0.316 0.000
M25 Other joint disorders, not elsewhere classified
0.684 0.316 0.000
N72 Inflammatory disease of cervix uteri
0.683 0.317 0.000
Z49 Care involving dialysis
0.683 0.317 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.683 0.317 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.682 0.318 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.682 0.318 0.000
Z03.0 Observation for suspected tuberculosis
0.682 0.318 0.000
H91 Other hearing loss
0.682 0.318 0.000
I24 Other acute ischaemic heart diseases
0.681 0.319 0.000
I85.9 Oesophageal varices without bleeding
0.679 0.321 0.000
E40-E46 Malnutrition
0.679 0.321 0.000
I80 Phlebitis and thrombophlebitis
0.678 0.322 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.677 0.323 0.000
I69 Sequelae of cerebrovascular disease
0.677 0.323 0.000
L71 Rosacea
0.676 0.324 0.000
J60-J70 Lung diseases due to external agents
0.676 0.324 0.000
I22 Subsequent myocardial infarction
0.675 0.325 0.000
L81.8 Other specified disorders of pigmentation
0.674 0.326 0.000
J37 Chronic laryngitis and laryngotracheitis
0.674 0.326 0.000
M65 Synovitis and tenosynovitis
0.674 0.326 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.673 0.327 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.673 0.327 0.000
B65-B83 Helminthiases
0.673 0.327 0.000
B50-B64 Protozoal diseases
0.673 0.327 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.673 0.327 0.000
A75-A79 Rickettsioses
0.673 0.327 0.000
A70-A74 Other diseases caused by chlamydiae
0.673 0.327 0.000
A65-A69 Other spirochaetal diseases
0.673 0.327 0.000
A20-A28 Certain zoonotic bacterial diseases
0.673 0.327 0.000
A15-A19 Tuberculosis
0.673 0.327 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.673 0.327 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.673 0.327 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.673 0.327 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.673 0.327 0.000
Z13.2 Special screening examination for nutritional disorders
0.673 0.327 0.000
D68.5 Primary Thrombophilia
0.673 0.327 0.000
B15-B19 Viral hepatitis
0.672 0.328 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.671 0.329 0.000
K50-K52 Noninfective enteritis and colitis
0.671 0.329 0.000
L53 Other erythematous conditions
0.670 0.330 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.669 0.331 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.668 0.332 0.000
K70-K77 Diseases of liver
0.668 0.332 0.000
J18.9 Pneumonia, unspecified
0.668 0.332 0.000
I61 Intracerebral haemorrhage
0.667 0.333 0.000
N71 Inflammatory disease of uterus, except cervix
0.667 0.333 0.000
L90.0 Lichen sclerosus et atrophicus
0.666 0.333 0.000
S20-S29 Injuries to the thorax
0.666 0.334 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.664 0.336 0.000
J30.1 Allergic rhinitis due to pollen
0.664 0.336 0.000
D67 Hereditary factor IX deficiency
0.664 0.336 0.000
D66 Hereditary factor VIII deficiency
0.664 0.336 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.664 0.336 0.000
M21 Other acquired deformities of limbs
0.663 0.336 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.663 0.337 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.663 0.337 0.000
L73 Other follicular disorders
0.663 0.337 0.000
E61 Deficiency of other nutrient elements
0.663 0.337 0.000
E87.6 Hypokalaemia
0.662 0.338 0.000
Z65 Problems related to other psychosocial circumstances
0.662 0.338 0.000
Z64 Problems related to certain psychosocial circumstances
0.662 0.338 0.000
Z62 Other problems related to upbringing
0.662 0.338 0.000
Z61 Problems related to negative life events in childhood
0.662 0.338 0.000
Z59 Problems related to housing and economic circumstances
0.662 0.338 0.000
Z58 Problems related to physical environment
0.662 0.338 0.000
Z56 Problems related to employment and unemployment
0.662 0.338 0.000
Z55 Problems related to education and literacy
0.662 0.338 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.662 0.338 0.000
Y45.8 Other analgesics and antipyretics
0.662 0.338 0.000
Y45.5 4-Aminophenol derivatives
0.662 0.338 0.000
Y45.4 Antirheumatics
0.662 0.338 0.000
I46.0 Cardiac arrest with successful resuscitation
0.661 0.339 0.000
D69 Purpura and other haemorrhagic conditions
0.661 0.339 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.660 0.340 0.000
Z52 Donors of organs and tissues
0.660 0.340 0.000
L60.9 Nail disorder, unspecified
0.660 0.340 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.660 0.340 0.000
Z48 Other surgical follow-up care
0.660 0.340 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.659 0.341 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.659 0.341 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.658 0.342 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.657 0.343 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.657 0.343 0.000
J17 Pneumonia in diseases classified elsewhere
0.656 0.344 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.656 0.344 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.656 0.344 0.000
J12 Viral pneumonia, not elsewhere classified
0.656 0.344 0.000
J10 Influenza due to identified influenza virus
0.656 0.344 0.000
J14 Pneumonia due to Haemophilus influenzae
0.656 0.344 0.000
J09 Influenza due to certain identified influenza virus
0.656 0.344 0.000
I20.9 Angina pectoris, unspecified
0.656 0.344 0.000
N02 Recurrent and persistent haematuria
0.656 0.344 0.000
G24.9 Dystonia, unspecified
0.656 0.344 0.000
J30.3 Other allergic rhinitis
0.655 0.345 0.000
Z51.2 Other chemotherapy
0.655 0.345 0.000
M51.8 Other specified intervertebral disk disorders
0.655 0.345 0.000
Z02.8 Other examinations for administrative purposes
0.654 0.346 0.000
J90-J94 Other diseases of pleura
0.654 0.346 0.000
E78.4 Other hyperlipidaemia
0.653 0.347 0.000
E87.5 Hyperkalaemia
0.652 0.348 0.000
N23 Unspecified renal colic
0.652 0.348 0.000
L75 Apocrine sweat disorders
0.652 0.348 0.000
L74 Eccrine sweat disorders
0.652 0.348 0.000
L70 Acne
0.652 0.348 0.000
L68 Hypertrichosis
0.652 0.348 0.000
L67 Hair colour and hair shaft abnormalities
0.652 0.348 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.652 0.348 0.000
L65 Other nonscarring hair loss
0.652 0.348 0.000
L64 Androgenic alopecia
0.652 0.348 0.000
L63 Alopecia areata
0.652 0.348 0.000
L62 Nail disorders in diseases classified elsewhere
0.652 0.348 0.000
Chapter XXII Codes for special purposes
0.652 0.348 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.651 0.348 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.651 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.651 0.348 0.000
G92 Toxic encephalopathy
0.651 0.348 0.000
Z51.8 Other specified medical care
0.651 0.349 0.000
B35-B49 Mycoses
0.651 0.349 0.000
H10-H13 Disorders of conjunctiva
0.650 0.350 0.000
I51.6 Cardiovascular disease, unspecified
0.649 0.351 0.000
I51.5 Myocardial degeneration
0.649 0.351 0.000
I51.4 Myocarditis, unspecified
0.649 0.351 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.649 0.351 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.649 0.351 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.649 0.351 0.000
I51.0 Cardiac septal defect, acquired
0.649 0.351 0.000
I82 Other venous embolism and thrombosis
0.649 0.351 0.000
L84 Corns and callosities
0.648 0.352 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.648 0.352 0.000
G35 Multiple sclerosis
0.648 0.352 0.000
H53.9 Visual disturbance, unspecified
0.648 0.352 0.000
Y42.5 Other oestrogens and progestogens
0.647 0.353 0.000
G96 Other disorders of central nervous system
0.646 0.354 0.000
Z01.9 Special examination, unspecified
0.646 0.354 0.000
L81.4 Other melanin hyperpigmentation
0.645 0.355 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.645 0.355 0.000
H92 Otalgia and effusion of ear
0.645 0.355 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.644 0.356 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
M46 Other inflammatory spondylopathies
0.644 0.356 0.000
I87 Other disorders of veins
0.643 0.357 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.642 0.358 0.000
H53.8 Other visual disturbances
0.642 0.358 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.641 0.359 0.000
G95 Other diseases of spinal cord
0.640 0.359 0.000
Z00.8 Other general examinations
0.640 0.360 0.000
Z00.5 Examination of potential donor of organ and tissue
0.640 0.360 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.640 0.360 0.000
Z00.3 Examination for adolescent development state
0.640 0.360 0.000
Z00.2 Examination for period of rapid growth in childhood
0.640 0.360 0.000
Z00.1 Routine child health examination
0.640 0.360 0.000
M24 Other specific joint derangements
0.640 0.360 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.640 0.360 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.640 0.360 0.000
L91 Hypertrophic disorders of skin
0.639 0.361 0.000
H18 Other disorders of cornea
0.639 0.361 0.000
I27.2 Other secondary pulmonary hypertension
0.639 0.361 0.000
K50 Crohn's disease [regional enteritis]
0.639 0.361 0.000
I81 Portal vein thrombosis
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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