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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56360506
log Bayes Factor = 10.2114
Chromosome 12   position 53,222,800  (GRCh37) Explore rs56360506 on Ensembl!
Variant rs56360506 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.997 0.003 0.000
L03 Cellulitis
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
I51 Complications and ill-defined descriptions of heart disease
0.984 0.016 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
I50 Heart failure
0.976 0.024 0.000
M50-M54 Other dorsopathies
0.975 0.025 0.000
I20-I25 Ischaemic heart diseases
0.973 0.027 0.000
M25 Other joint disorders, not elsewhere classified
0.964 0.036 0.000
I51.7 Cardiomegaly
0.962 0.038 0.000
I50.1 Left ventricular failure
0.959 0.041 0.000
M25.5 Pain in joint
0.958 0.042 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.957 0.043 0.000
M80-M85 Disorders of bone density and structure
0.957 0.043 0.000
L20-L30 Dermatitis and eczema
0.953 0.047 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.949 0.051 0.000
I51.8 Other ill-defined heart diseases
0.946 0.054 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.945 0.055 0.000
M51 Other intervertebral disk disorders
0.944 0.056 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.941 0.059 0.000
L03.2 Cellulitis of face
0.939 0.061 0.000
M25.51 Pain in joint (Shoulder region)
0.934 0.066 0.000
I22 Subsequent myocardial infarction
0.931 0.069 0.000
L03.9 Cellulitis, unspecified
0.927 0.073 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.927 0.073 0.000
Chapter VI Diseases of the nervous system
0.921 0.079 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.919 0.081 0.000
I24 Other acute ischaemic heart diseases
0.917 0.083 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.912 0.088 0.000
M51.2 Other specified intervertebral disk displacement
0.912 0.088 0.000
M25.50 Pain in joint (Multiple sites)
0.906 0.094 0.000
M81 Osteoporosis without pathological fracture
0.893 0.107 0.000
M35 Other systemic involvement of connective tissue
0.892 0.108 0.000
Q50-Q56 Congenital malformations of genital organs
0.892 0.108 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.888 0.112 0.000
M86-M90 Other osteopathies
0.887 0.113 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.882 0.118 0.000
L03.8 Cellulitis of other sites
0.881 0.119 0.000
M24 Other specific joint derangements
0.880 0.120 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.874 0.126 0.000
T66-T78 Other and unspecified effects of external causes
0.873 0.127 0.000
M45 Ankylosing spondylitis
0.872 0.128 0.000
Y52 Agents primarily affecting the cardiovascular system
0.871 0.129 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.871 0.129 0.000
M84 Disorders of continuity of bone
0.870 0.130 0.000
E20-E35 Disorders of other endocrine glands
0.867 0.133 0.000
L90 Atrophic disorders of skin
0.866 0.134 0.000
M50 Cervical disk disorders
0.866 0.134 0.000
M48 Other spondylopathies
0.863 0.137 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.862 0.138 0.000
Chapter XXII Codes for special purposes
0.858 0.142 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.856 0.144 0.000
M81.9 Osteoporosis, unspecified
0.856 0.144 0.000
I31 Other diseases of pericardium
0.854 0.146 0.000
L29 Pruritus
0.853 0.147 0.000
L28 Lichen simplex chronicus and prurigo
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.846 0.154 0.000
E00-E07 Disorders of thyroid gland
0.845 0.155 0.000
M51.4 Schmorl's nodes
0.843 0.157 0.000
I51.4 Myocarditis, unspecified
0.842 0.158 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.840 0.160 0.000
M50.1 Cervical disk disorder with radiculopathy
0.840 0.160 0.000
M21 Other acquired deformities of limbs
0.840 0.160 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.839 0.161 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.837 0.163 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.837 0.163 0.000
M47 Spondylosis
0.835 0.165 0.000
S90-S99 Injuries to the ankle and foot
0.832 0.168 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.831 0.168 0.000
W50-W64 Exposure to animate mechanical forces
0.827 0.173 0.000
L08 Other local infections of skin and subcutaneous tissue
0.826 0.174 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.826 0.174 0.000
X60-X84 Intentional self-harm
0.824 0.176 0.000
I24.8 Other forms of acute ischaemic heart disease
0.824 0.176 0.000
I37 Pulmonary valve disorders
0.822 0.178 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.819 0.181 0.000
L05 Pilonidal cyst
0.818 0.182 0.000
Chapter I Certain infectious and parasitic diseases
0.817 0.183 0.000
M25.54 Pain in joint (Hand)
0.815 0.185 0.000
T43.2 Other and unspecified antidepressants
0.815 0.185 0.000
T86 Failure and rejection of transplanted organs and tissues
0.810 0.190 0.000
M89 Other disorders of bone
0.810 0.190 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.809 0.190 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.808 0.192 0.000
I31.9 Disease of pericardium, unspecified
0.806 0.194 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.805 0.195 0.000
Q54 Hypospadias
0.805 0.195 0.000
M35.3 Polymyalgia rheumatica
0.805 0.195 0.000
L90.0 Lichen sclerosus et atrophicus
0.803 0.197 0.000
M25.52 Pain in joint (Upper arm)
0.801 0.199 0.000
E40-E46 Malnutrition
0.801 0.199 0.000
M47.8 Other spondylosis
0.800 0.200 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.798 0.202 0.000
I50.9 Heart failure, unspecified
0.798 0.202 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.796 0.204 0.000
M48.0 Spinal stenosis
0.795 0.205 0.000
Chapter X Diseases of the respiratory system
0.793 0.207 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.793 0.207 0.000
G81 Hemiplegia
0.793 0.207 0.000
M70-M79 Other soft tissue disorders
0.792 0.208 0.000
B15-B19 Viral hepatitis
0.790 0.210 0.000
X50-X57 Overexertion, travel and privation
0.790 0.210 0.000
M84.0 Malunion of fracture
0.789 0.211 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.788 0.212 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.786 0.214 0.000
J40-J47 Chronic lower respiratory diseases
0.785 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.784 0.216 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.783 0.217 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.783 0.217 0.000
M65-M68 Disorders of synovium and tendon
0.780 0.220 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.779 0.221 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.779 0.221 0.000
Y84.8 Other medical procedures
0.778 0.222 0.000
L28.0 Lichen simplex chronicus
0.777 0.223 0.000
V80-V89 Other land transport accidents
0.774 0.226 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.774 0.226 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.773 0.227 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.771 0.229 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.771 0.229 0.000
I95 Hypotension
0.769 0.231 0.000
T78 Adverse effects, not elsewhere classified
0.769 0.231 0.000
Y43 Primarily systemic agents
0.768 0.232 0.000
M49 Spondylopathies in diseases classified elsewhere
0.767 0.233 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.766 0.234 0.000
M81.98 Osteoporosis, unspecified (Other)
0.763 0.237 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.761 0.238 0.000
Y52.1 Calcium-channel blockers
0.761 0.239 0.000
M25.58 Pain in joint (Other)
0.761 0.239 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.761 0.239 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.760 0.240 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.760 0.240 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.758 0.242 0.000
I50.0 Congestive heart failure
0.758 0.242 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
T36 Poisoning by systemic antibiotics
0.754 0.246 0.000
L20 Atopic dermatitis
0.754 0.246 0.000
M25.8 Other specified joint disorders
0.753 0.247 0.000
G83 Other paralytic syndromes
0.753 0.247 0.000
I70 Atherosclerosis
0.752 0.248 0.000
M46 Other inflammatory spondylopathies
0.751 0.249 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.749 0.251 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.747 0.253 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.746 0.254 0.000
M25.59 Pain in joint (Site unspecified)
0.744 0.256 0.000
M21.3 Wrist or foot drop (acquired)
0.743 0.257 0.000
I27 Other pulmonary heart diseases
0.742 0.258 0.000
L91 Hypertrophic disorders of skin
0.741 0.259 0.000
I38 Endocarditis, valve unspecified
0.740 0.260 0.000
G90-G99 Other disorders of the nervous system
0.740 0.260 0.000
I22.8 Subsequent myocardial infarction of other sites
0.740 0.260 0.000
L21 Seborrhoeic dermatitis
0.739 0.261 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.739 0.261 0.000
L60-L75 Disorders of skin appendages
0.739 0.261 0.000
W00-W19 Falls
0.739 0.261 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.738 0.262 0.000
L83 Acanthosis nigricans
0.737 0.263 0.000
G81.9 Hemiplegia, unspecified
0.737 0.263 0.000
I95.1 Orthostatic hypotension
0.736 0.264 0.000
L29.9 Pruritus, unspecified
0.735 0.265 0.000
J47 Bronchiectasis
0.734 0.266 0.000
T87 Complications peculiar to reattachment and amputation
0.734 0.266 0.000
X20-X29 Contact with venomous animals and plants
0.733 0.266 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.732 0.268 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.731 0.269 0.000
L03.0 Cellulitis of finger and toe
0.731 0.269 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.729 0.270 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.729 0.271 0.000
M86 Osteomyelitis
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
M35.0 Sicca syndrome [Sjogren]
0.728 0.272 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
I20 Angina pectoris
0.727 0.273 0.000
Y00-Y09 Assault
0.725 0.275 0.000
L94 Other localised connective tissue disorders
0.725 0.275 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.724 0.276 0.000
J45 Asthma
0.723 0.277 0.000
S91 Open wound of ankle and foot
0.723 0.277 0.000
G40-G47 Episodic and paroxysmal disorders
0.723 0.277 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.722 0.278 0.000
I78 Diseases of capillaries
0.722 0.278 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.722 0.278 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.722 0.278 0.000
T79-T79 Certain early complications of trauma
0.720 0.279 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.280 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.719 0.280 0.000
A80-A89 Viral infections of the central nervous system
0.719 0.281 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.718 0.281 0.000
E07 Other disorders of thyroid
0.717 0.283 0.000
Q80-Q89 Other congenital malformations
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.717 0.283 0.000
E22 Hyperfunction of pituitary gland
0.715 0.285 0.000
L71 Rosacea
0.715 0.285 0.000
M25.3 Other instability of joint
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
L04 Acute lymphadenitis
0.714 0.285 0.000
L01 Impetigo
0.714 0.285 0.000
L00 Staphylococcal scalded skin syndrome
0.714 0.285 0.000
I51.6 Cardiovascular disease, unspecified
0.713 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
M48.06 Spinal stenosis (Lumbar region)
0.711 0.289 0.000
G03 Meningitis due to other and unspecified causes
0.711 0.289 0.000
E46 Unspecified protein-energy malnutrition
0.711 0.289 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.710 0.290 0.000
M89.9 Disorder of bone, unspecified
0.708 0.292 0.000
Q54.9 Hypospadias, unspecified
0.708 0.292 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
M47.86 Other spondylosis (Lumbar region)
0.708 0.292 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.706 0.294 0.000
I51.5 Myocardial degeneration
0.706 0.294 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.706 0.294 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.706 0.294 0.000
I51.0 Cardiac septal defect, acquired
0.706 0.294 0.000
Y44 Agents primarily affecting blood constituents
0.706 0.294 0.000
L05.9 Pilonidal cyst without abscess
0.705 0.295 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.704 0.296 0.000
I37.1 Pulmonary valve insufficiency
0.703 0.297 0.000
L85 Other epidermal thickening
0.703 0.297 0.000
I46 Cardiac arrest
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.299 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.701 0.299 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.701 0.299 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.700 0.300 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.699 0.300 0.000
J40 Bronchitis, not specified as acute or chronic
0.699 0.300 0.000
M25.53 Pain in joint (Forearm)
0.699 0.301 0.000
M25.0 Haemarthrosis
0.699 0.301 0.000
I23 Certain current complications following acute myocardial infarction
0.697 0.303 0.000
L71.9 Rosacea, unspecified
0.697 0.303 0.000
I25 Chronic ischaemic heart disease
0.697 0.303 0.000
M25.7 Osteophyte
0.697 0.303 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
S12 Fracture of neck
0.696 0.304 0.000
J45.9 Asthma, unspecified
0.695 0.305 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.695 0.305 0.000
M82 Osteoporosis in diseases classified elsewhere
0.694 0.306 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.694 0.306 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.694 0.306 0.000
I77 Other disorders of arteries and arterioles
0.693 0.307 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.693 0.307 0.000
M24.2 Disorder of ligament
0.693 0.307 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.692 0.308 0.000
M25.2 Flail joint
0.691 0.309 0.000
M25.1 Fistula of joint
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.690 0.310 0.000
J43 Emphysema
0.690 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.690 0.310 0.000
M53 Other dorsopathies, not elsewhere classified
0.689 0.310 0.000
M85 Other disorders of bone density and structure
0.689 0.311 0.000
J95-J99 Other diseases of the respiratory system
0.689 0.311 0.000
E23 Hypofunction and other disorders of pituitary gland
0.689 0.311 0.000
T45.0 Antiallergic and antiemetic drugs
0.689 0.311 0.000
E27 Other disorders of adrenal gland
0.686 0.314 0.000
L50-L54 Urticaria and erythema
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.686 0.314 0.000
Y58 Bacterial vaccines
0.686 0.314 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.686 0.314 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.686 0.314 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.686 0.314 0.000
M83 Adult osteomalacia
0.686 0.314 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.684 0.316 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.684 0.316 0.000
L25 Unspecified contact dermatitis
0.683 0.317 0.000
L24 Irritant contact dermatitis
0.683 0.317 0.000
L23 Allergic contact dermatitis
0.683 0.317 0.000
L26 Exfoliative dermatitis
0.683 0.317 0.000
L22 Diaper [napkin] dermatitis
0.683 0.317 0.000
Y43.4 Immunosuppressive agents
0.682 0.318 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.319 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.681 0.319 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.681 0.319 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.680 0.319 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.680 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.680 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
T86.0 Bone-marrow transplant rejection
0.678 0.322 0.000
M75 Shoulder lesions
0.678 0.322 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.678 0.322 0.000
Q35-Q37 Cleft lip and cleft palate
0.678 0.322 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.678 0.322 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.677 0.323 0.000
M51.3 Other specified intervertebral disk degeneration
0.677 0.323 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.677 0.323 0.000
I45 Other conduction disorders
0.677 0.323 0.000
M25.57 Pain in joint (Ankle and foot)
0.676 0.324 0.000
Q76 Congenital malformations of spine and bony thorax
0.675 0.324 0.000
W06 Fall involving bed
0.675 0.325 0.000
L27 Dermatitis due to substances taken internally
0.675 0.325 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.675 0.325 0.000
L87 Transepidermal elimination disorders
0.675 0.325 0.000
L88 Pyoderma gangrenosum
0.675 0.325 0.000
L86 Keratoderma in diseases classified elsewhere
0.675 0.325 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.674 0.326 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.674 0.326 0.000
M91-M94 Chondropathies
0.674 0.326 0.000
L93 Lupus erythematosus
0.673 0.327 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.673 0.327 0.000
L29.0 Pruritus ani
0.672 0.328 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.671 0.329 0.000
B19 Unspecified viral hepatitis
0.671 0.329 0.000
S20-S29 Injuries to the thorax
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.331 0.000
I95.2 Hypotension due to drugs
0.669 0.331 0.000
L80 Vitiligo
0.669 0.331 0.000
B18 Chronic viral hepatitis
0.669 0.331 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.669 0.331 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.668 0.332 0.000
E05.9 Thyrotoxicosis, unspecified
0.668 0.332 0.000
S40-S49 Injuries to the shoulder and upper arm
0.668 0.332 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.667 0.333 0.000
I05-I09 Chronic rheumatic heart diseases
0.666 0.334 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.665 0.335 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.665 0.335 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.663 0.337 0.000
I74 Arterial embolism and thrombosis
0.662 0.338 0.000
I27.2 Other secondary pulmonary hypertension
0.662 0.338 0.000
T18 Foreign body in alimentary tract
0.661 0.339 0.000
G83.1 Monoplegia of lower limb
0.661 0.339 0.000
S50-S59 Injuries to the elbow and forearm
0.661 0.339 0.000
G95 Other diseases of spinal cord
0.661 0.339 0.000
B15 Acute hepatitis A
0.661 0.339 0.000
X78 Intentional self-harm by sharp object
0.660 0.339 0.000
M65 Synovitis and tenosynovitis
0.660 0.340 0.000
B17 Other acute viral hepatitis
0.660 0.340 0.000
W55 Bitten or struck by other mammals
0.659 0.341 0.000
Q54.1 Hypospadias, penile
0.659 0.341 0.000
L82 Seborrhoeic keratosis
0.659 0.341 0.000
I36 Nonrheumatic tricuspid valve disorders
0.658 0.342 0.000
Y40 Systemic antibiotics
0.658 0.342 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.658 0.342 0.000
M84.06 Malunion of fracture (Lower leg)
0.658 0.342 0.000
I72 Other aneurysm
0.658 0.342 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.657 0.343 0.000
I24.1 Dressler's syndrome
0.657 0.343 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.657 0.343 0.000
L90.5 Scar conditions and fibrosis of skin
0.657 0.343 0.000
M84.4 Pathological fracture, not elsewhere classified
0.657 0.343 0.000
T68 Hypothermia
0.657 0.343 0.000
M76 Enthesopathies of lower limb, excluding foot
0.657 0.343 0.000
M24.1 Other articular cartilage disorders
0.656 0.344 0.000
M40-M43 Deforming dorsopathies
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.656 0.344 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.654 0.346 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.654 0.346 0.000
L29.8 Other pruritus
0.654 0.346 0.000
G00 Bacterial meningitis, not elsewhere classified
0.653 0.346 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.652 0.347 0.000
G80 Infantile cerebral palsy
0.651 0.349 0.000
G47 Sleep disorders
0.651 0.349 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.649 0.351 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.649 0.351 0.000
D86 Sarcoidosis
0.648 0.352 0.000
M89.0 Algoneurodystrophy
0.647 0.353 0.000
M84.01 Malunion of fracture (Shoulder region)
0.645 0.355 0.000
M24.5 Contracture of joint
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.644 0.356 0.000
Chapter VIII Diseases of the ear and mastoid process
0.643 0.357 0.000
M81.8 Other osteoporosis
0.640 0.360 0.000
M81.6 Localised osteoporosis [Lequesne]
0.640 0.360 0.000
M81.5 Idiopathic osteoporosis
0.640 0.360 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.640 0.360 0.000
M81.2 Osteoporosis of disuse
0.640 0.360 0.000
M81.1 Postoophorectomy osteoporosis
0.640 0.360 0.000
M81.0 Postmenopausal osteoporosis
0.640 0.360 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.639 0.360 0.000
M35.8 Other specified systemic involvement of connective tissue
0.639 0.360 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.639 0.360 0.000
M35.5 Multifocal fibrosclerosis
0.639 0.360 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.639 0.360 0.000
M35.2 Behcet's disease
0.639 0.360 0.000
M35.1 Other overlap syndromes
0.639 0.360 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.639 0.361 0.000
Q55 Other congenital malformations of male genital organs
0.639 0.361 0.000
Q53 Undescended testicle
0.639 0.361 0.000
Q52 Other congenital malformations of female genitalia
0.639 0.361 0.000
L81 Other disorders of pigmentation
0.639 0.361 0.000
L03.1 Cellulitis of other parts of limb
0.639 0.361 0.000
M21.1 Varus deformity, not elsewhere classified
0.638 0.362 0.000
Y46.6 Other and unspecified antiepileptics
0.638 0.362 0.000
E34 Other endocrine disorders
0.637 0.363 0.000
I30 Acute pericarditis
0.637 0.363 0.000
L89 Decubitus ulcer
0.636 0.363 0.000
M75.1 Rotator cuff syndrome
0.637 0.363 0.000
T90 Sequelae of injuries of head
0.636 0.364 0.000
T46.1 Calcium-channel blockers
0.636 0.364 0.000
E65-E68 Obesity and other hyperalimentation
0.635 0.365 0.000
J98 Other respiratory disorders
0.635 0.365 0.000
T78.4 Allergy, unspecified
0.634 0.366 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.632 0.368 0.000
T78.3 Angioneurotic oedema
0.631 0.369 0.000
T92 Sequelae of injuries of upper limb
0.631 0.369 0.000
M24.9 Joint derangement, unspecified
0.631 0.369 0.000
M24.7 Protrusio acetabuli
0.631 0.369 0.000
M24.6 Ankylosis of joint
0.631 0.369 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.630 0.370 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.630 0.370 0.000
W06.0 Home
0.630 0.370 0.000
E21.0 Primary hyperparathyroidism
0.629 0.371 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.627 0.372 0.000
Q51 Congenital malformations of uterus and cervix
0.626 0.373 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.627 0.373 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.626 0.374 0.000
T75 Effects of other external causes
0.626 0.374 0.000
T74 Maltreatment syndromes
0.626 0.374 0.000
T73 Effects of other deprivation
0.626 0.374 0.000
T70 Effects of air pressure and water pressure
0.626 0.374 0.000
T69 Other effects of reduced temperature
0.626 0.374 0.000
T67 Effects of heat and light
0.626 0.374 0.000
T71 Asphyxiation
0.626 0.374 0.000
T66 Unspecified effects of radiation
0.626 0.374 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.626 0.374 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.625 0.375 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.625 0.375 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.625 0.375 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.625 0.375 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.625 0.375 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.625 0.375 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.625 0.375 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.625 0.375 0.000
J42 Unspecified chronic bronchitis
0.625 0.375 0.000
A87 Viral meningitis
0.625 0.375 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.624 0.376 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.624 0.376 0.000
Y52.7 Peripheral vasodilators
0.624 0.376 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.624 0.376 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.624 0.376 0.000
J43.9 Emphysema, unspecified
0.624 0.376 0.000
M84.9 Disorder of continuity of bone, unspecified
0.624 0.376 0.000
M84.8 Other disorders of continuity of bone
0.624 0.376 0.000
M84.3 Stress fracture, not elsewhere classified
0.624 0.376 0.000
M84.2 Delayed union of fracture
0.624 0.376 0.000
I73 Other peripheral vascular diseases
0.623 0.377 0.000
Q66 Congenital deformities of feet
0.623 0.377 0.000
T81 Complications of procedures, not elsewhere classified
0.623 0.377 0.000
G90 Disorders of autonomic nervous system
0.623 0.377 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.623 0.377 0.000
M25.9 Joint disorder, unspecified
0.622 0.378 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.621 0.378 0.000
E32 Diseases of thymus
0.621 0.378 0.000
E31 Polyglandular dysfunction
0.621 0.378 0.000
E30 Disorders of puberty, not elsewhere classified
0.621 0.378 0.000
E26 Hyperaldosteronism
0.621 0.378 0.000
E25 Adrenogenital disorders
0.621 0.378 0.000
E24 Cushing's syndrome
0.621 0.378 0.000
E20 Hypoparathyroidism
0.621 0.378 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.621 0.379 0.000
L90.9 Atrophic disorder of skin, unspecified
0.621 0.379 0.000
L90.8 Other atrophic disorders of skin
0.621 0.379 0.000
L90.6 Striae atrophicae
0.621 0.379 0.000
L90.4 Acrodermatitis chronica atrophicans
0.621 0.379 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.621 0.379 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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