TreeWAS – Variant ID: rs5754227

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.869	0.131
O80.0 Spontaneous vertex delivery	0.000	0.989	0.011
H04.5 Stenosis and insufficiency of lachrymal passages	0.009	0.991	0.000
O80 Single spontaneous delivery	0.000	0.991	0.009
O80.9 Single spontaneous delivery, unspecified	0.000	0.992	0.008
O80.8 Other single spontaneous delivery	0.000	0.993	0.007
Z86.7 Personal history of diseases of the circulatory system	0.000	0.993	0.007
O80.1 Spontaneous breech delivery	0.000	0.993	0.006
I21 Acute myocardial infarction	0.000	0.994	0.006
I67.9 Cerebrovascular disease, unspecified	0.000	0.994	0.006
H04.2 Epiphora	0.006	0.994	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.995	0.005
I21.4 Acute subendocardial myocardial infarction	0.000	0.995	0.005
H04 Disorders of lachrymal system	0.005	0.995	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.995	0.005
H50.0 Convergent concomitant strabismus	0.000	0.996	0.004
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.004	0.996	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.996	0.004
O41.0 Oligohydramnios	0.004	0.996	0.000
H04.6 Other changes in lachrymal passages	0.004	0.996	0.000
H04.0 Dacryoadenitis	0.004	0.996	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.004	0.996	0.000
D07.5 Prostate	0.004	0.996	0.000
H04.8 Other disorders of lachrymal system	0.003	0.996	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.997	0.003
H04.4 Chronic inflammation of lachrymal passages	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.000	0.997	0.003
H25.8 Other senile cataract	0.000	0.997	0.003
H04.9 Disorder of lachrymal system, unspecified	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
M48.07 Spinal stenosis (Lumbosacral region)	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
H50.9 Strabismus, unspecified	0.000	0.997	0.003
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.997	0.003
O80-O84 Delivery	0.000	0.997	0.003
D07.2 Vagina	0.003	0.997	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
N85.2 Hypertrophy of uterus	0.003	0.997	0.000
H50 Other strabismus	0.000	0.997	0.003
N48.6 Balanitis xerotica obliterans	0.000	0.997	0.003
C25.9 Pancreas, unspecified	0.000	0.997	0.003
L92 Granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
D07.1 Vulva	0.003	0.997	0.000
C25.0 Head of pancreas	0.000	0.997	0.003
M48.0 Spinal stenosis	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
M48.04 Spinal stenosis (Thoracic region)	0.002	0.997	0.000
H50.2 Vertical strabismus	0.000	0.997	0.002
C25 Malignant neoplasm of pancreas	0.000	0.997	0.003
C25.2 Tail of pancreas	0.000	0.997	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.002
D04.5 Skin of trunk	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
D07.0 Endometrium	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.002	0.998	0.000
O84 Multiple delivery	0.000	0.998	0.002
O83 Other assisted single delivery	0.000	0.998	0.002
H50.8 Other specified strabismus	0.000	0.998	0.002
H50.6 Mechanical strabismus	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.000	0.998	0.002
K13.7 Other and unspecified lesions of oral mucosa	0.002	0.998	0.000
D07.4 Penis	0.002	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
H50.5 Heterophoria	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.002	0.998	0.000
C25.1 Body of pancreas	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.000	0.998	0.002
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.002	0.998	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
F17.2 Dependence syndrome	0.002	0.998	0.000
G81 Hemiplegia	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
C25.3 Pancreatic duct	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.000	0.998	0.002
Z36.8 Other antenatal screening	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
L92.0 Granuloma annulare	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.000	0.998	0.002
O83.9 Assisted single delivery, unspecified	0.000	0.998	0.002
O83.8 Other specified assisted single delivery	0.000	0.998	0.002
O83.4 Destructive operation for delivery	0.000	0.998	0.002
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.998	0.002
O83.2 Other manipulation-assisted delivery	0.000	0.998	0.002
O83.1 Other assisted breech delivery	0.000	0.998	0.002
O83.0 Breech extraction	0.000	0.998	0.002
O84.9 Multiple delivery, unspecified	0.000	0.998	0.002
O84.8 Other multiple delivery	0.000	0.998	0.002
O84.2 Multiple delivery, all by Caesarean section	0.000	0.998	0.002
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.998	0.002
O84.0 Multiple delivery, all spontaneous	0.000	0.998	0.002
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
S22.50 Flail chest (closed)	0.000	0.998	0.002
S22.5 Flail chest	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.000	0.998	0.002
O81.2 Mid-cavity forceps with rotation	0.000	0.998	0.002
O81.1 Mid-cavity forceps delivery	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.000	0.998	0.002
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
G83 Other paralytic syndromes	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
I51.7 Cardiomegaly	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
F12.1 Harmful use	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.998	0.002
O81.0 Low forceps delivery	0.000	0.998	0.002
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.000	0.998	0.002
G81.0 Flaccid hemiplegia	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
D00-D09 In situ neoplasms	0.002	0.998	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.998	0.002
O82.2 Delivery by Caesarean hysterectomy	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
H04.1 Other disorders of lachrymal gland	0.001	0.998	0.000
I42.8 Other cardiomyopathies	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.998	0.002
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
S22.51 Flail chest (open)	0.000	0.998	0.001
D48.0 Bone and articular cartilage	0.000	0.998	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.001
N85.8 Other specified noninflammatory disorders of uterus	0.002	0.998	0.000
R18 Ascites	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
D48.5 Skin	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.000	0.998	0.001
G83.3 Monoplegia, unspecified	0.000	0.998	0.001
G83.0 Diplegia of upper limbs	0.000	0.998	0.001
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.001
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.002	0.998	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.998	0.001
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.998	0.002
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.001	0.998	0.000
N42 Other disorders of prostate	0.000	0.998	0.002
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.001
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.998	0.002
C90.0 Multiple myeloma	0.002	0.998	0.000
N42.0 Calculus of prostate	0.000	0.998	0.001
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.998	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.001	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.001
M48.06 Spinal stenosis (Lumbar region)	0.002	0.998	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.001
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.001
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.001
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.001
O34.0 Maternal care for congenital malformation of uterus	0.001	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
D06.9 Cervix, unspecified	0.001	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.001	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.001
D02 Carcinoma in situ of middle ear and respiratory system	0.001	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.999	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
D00.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
D06.7 Other parts of cervix	0.001	0.999	0.000
D06.1 Exocervix	0.001	0.999	0.000
D06.0 Endocervix	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.999	0.000
S22.3 Fracture of rib	0.000	0.999	0.001
Q05 Spina bifida	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
M87.8 Other osteonecrosis	0.001	0.999	0.000
N32.3 Diverticulum of bladder	0.000	0.999	0.001
O32.8 Maternal care for other malpresentation of foetus	0.001	0.999	0.000
O34.4 Maternal care for other abnormalities of cervix	0.001	0.999	0.000
M87 Osteonecrosis	0.001	0.999	0.000
D00.2 Stomach	0.001	0.999	0.000
D00.1 Oesophagus	0.001	0.999	0.000
G83.1 Monoplegia of lower limb	0.000	0.999	0.001
N42.3 Dysplasia of prostate	0.000	0.999	0.001
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.999	0.000
O34.6 Maternal care for abnormality of vagina	0.001	0.999	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.001	0.999	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000
S83.1 Dislocation of knee	0.001	0.999	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.999	0.001
S22.21 Fracture of sternum (open)	0.000	0.999	0.001
D48.1 Connective and other soft tissue	0.000	0.999	0.001
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.999	0.001
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
D01.9 Digestive organ, unspecified	0.001	0.999	0.000
D01.7 Other specified digestive organs	0.001	0.999	0.000
D01.5 Liver, gallbladder and bile ducts	0.001	0.999	0.000
D01.4 Other and unspecified parts of intestine	0.001	0.999	0.000
D01.3 Anus and anal canal	0.001	0.999	0.000
D01.2 Rectum	0.001	0.999	0.000
D01.1 Rectosigmoid junction	0.001	0.999	0.000
D01.0 Colon	0.001	0.999	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.999	0.001
O48 Prolonged pregnancy	0.001	0.999	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.999	0.001
H60.1 Cellulitis of external ear	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
Y42.4 Oral contraceptives	0.000	0.999	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.999	0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.999	0.001
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.999	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
D02.4 Respiratory system, unspecified	0.001	0.999	0.000
D02.3 Other parts of respiratory system	0.001	0.999	0.000
D02.2 Bronchus and lung	0.001	0.999	0.000
D02.1 Trachea	0.001	0.999	0.000
G80.8 Other infantile cerebral palsy	0.000	0.999	0.001
G80.4 Ataxic cerebral palsy	0.000	0.999	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.999	0.001
G80.1 Spastic diplegia	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
H50.1 Divergent concomitant strabismus	0.000	0.999	0.001
O32.3 Maternal care for face, brow and chin presentation	0.001	0.999	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.999	0.001
S83.3 Tear of articular cartilage of knee, current	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.999	0.001
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.999	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.999	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.86 Other osteonecrosis (Lower leg)	0.001	0.999	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.999	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.999	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.999	0.000
S22.31 Fracture of rib (open)	0.000	0.999	0.001
J95.0 Tracheostomy malfunction	0.001	0.999	0.000
K86.1 Other chronic pancreatitis	0.000	0.999	0.001
M87.3 Other secondary osteonecrosis	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.999	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
C45 Mesothelioma	0.001	0.999	0.000
D04.7 Skin of lower limb, including hip	0.001	0.999	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.999	0.001
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.001	0.999	0.000
D02.0 Larynx	0.001	0.999	0.000
D48.7 Other specified sites	0.000	0.999	0.001
G80.2 Infantile hemiplegia	0.000	0.999	0.001
D09 Carcinoma in situ of other and unspecified sites	0.001	0.999	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.999	0.001
D48.4 Peritoneum	0.000	0.999	0.001
D48.3 Retroperitoneum	0.000	0.999	0.001
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.999	0.001
O32.6 Maternal care for compound presentation	0.001	0.999	0.000
O34.1 Maternal care for tumour of corpus uteri	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.999	0.001
D05 Carcinoma in situ of breast	0.001	0.999	0.000
N48 Other disorders of penis	0.000	0.999	0.001
M48.86 Other specified spondylopathies (Lumbar region)	0.001	0.999	0.000
D48.6 Breast	0.000	0.999	0.001
J20.9 Acute bronchitis, unspecified	0.001	0.999	0.000
L91.0 Keloid scar	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.001	0.999	0.000
Z84.8 Family history of other specified conditions	0.000	0.999	0.001
D03 Melanoma in situ	0.001	0.999	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.999	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.999	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.999	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.999	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.999	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.999	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.999	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.999	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.999	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.999	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.999	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.999	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.999	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.001	0.999	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.999	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.999	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.999	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.999	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.999	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.38 Other secondary osteonecrosis (Other)	0.001	0.999	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.001	0.999	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.001	0.999	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.001	0.999	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
M48.8 Other specified spondylopathies	0.001	0.999	0.000
N48.1 Balanoposthitis	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.000	0.999	0.001
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.999	0.001
C67.0 Trigone of bladder	0.000	0.999	0.001
G31.9 Degenerative disease of nervous system, unspecified	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
R59.1 Generalised enlarged lymph nodes	0.000	0.999	0.001
S22.20 Fracture of sternum (closed)	0.000	0.999	0.001
D03.5 Melanoma in situ of trunk	0.000	0.999	0.001
D09.9 Carcinoma in situ, unspecified	0.001	0.999	0.000
D09.7 Carcinoma in situ of other specified sites	0.001	0.999	0.000
D09.3 Thyroid and other endocrine glands	0.001	0.999	0.000
D09.2 Eye	0.001	0.999	0.000
D09.1 Other and unspecified urinary organs	0.001	0.999	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.999	0.001
S27.8 Injury of other specified intrathoracic organs	0.000	0.999	0.001
S27.7 Multiple injuries of intrathoracic organs	0.000	0.999	0.001
S27.6 Injury of pleura	0.000	0.999	0.001
S27.5 Injury of thoracic trachea	0.000	0.999	0.001
S27.4 Injury of bronchus	0.000	0.999	0.001
S83.7 Injury to multiple structures of knee	0.001	0.999	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
S83.0 Dislocation of patella	0.001	0.999	0.000
M48 Other spondylopathies	0.001	0.999	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.999	0.001
D03.9 Melanoma in situ, unspecified	0.001	0.999	0.000
D03.8 Melanoma in situ of other sites	0.001	0.999	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.001	0.999	0.000
D03.0 Melanoma in situ of lip	0.001	0.999	0.000
D05.7 Other carcinoma in situ of breast	0.001	0.999	0.000
M34.8 Other forms of systemic sclerosis	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.999	0.001
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.999	0.001
O33.9 Maternal care for disproportion, unspecified	0.001	0.999	0.000
R47.0 Dysphasia and aphasia	0.000	0.999	0.001
S27.1 Traumatic haemothorax	0.000	0.999	0.001
T09.0 Superficial injury of trunk, level unspecified	0.001	0.999	0.000
Z71.8 Other specified counselling	0.000	0.999	0.001
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
C16.0 Cardia	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.001	0.999	0.000
N48.5 Ulcer of penis	0.000	0.999	0.001
N85.7 Haematometra	0.001	0.999	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.999	0.001
O33 Maternal care for known or suspected disproportion	0.001	0.999	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.001	0.999	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.001	0.999	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.001	0.999	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.001	0.999	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.001	0.999	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.999	0.001
C67.8 Overlapping lesion of bladder	0.000	0.999	0.001
C67.3 Anterior wall of bladder	0.000	0.999	0.001
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.999	0.000
D05.1 Intraductal carcinoma in situ	0.001	0.999	0.000
H47.3 Other disorders of optic disk	0.001	0.999	0.000
H52.0 Hypermetropia	0.000	0.999	0.001
N48.9 Disorder of penis, unspecified	0.000	0.999	0.001
N48.8 Other specified disorders of penis	0.000	0.999	0.001
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.999	0.000
O32.4 Maternal care for high head at term	0.001	0.999	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
C67 Malignant neoplasm of bladder	0.000	0.999	0.001
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.999	0.001
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.999	0.001
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.999	0.001
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.999	0.001
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.999	0.001
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.999	0.001
A04.5 Campylobacter enteritis	0.000	0.999	0.001
D05.9 Carcinoma in situ of breast, unspecified	0.001	0.999	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.999	0.001
H66.9 Otitis media, unspecified	0.000	0.999	0.001
J95.9 Postprocedural respiratory disorder, unspecified	0.001	0.999	0.000
K56.7 Ileus, unspecified	0.000	0.999	0.001
M48.9 Spondylopathy, unspecified	0.001	0.999	0.000
M48.4 Fatigue fracture of vertebra	0.001	0.999	0.000
M48.3 Traumatic spondylopathy	0.001	0.999	0.000
M48.2 Kissing spine	0.001	0.999	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.001	0.999	0.000
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
S27.3 Other injuries of lung	0.000	0.999	0.001
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.999	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.999	0.000
O33.8 Maternal care for disproportion of other origin	0.001	0.999	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.001	0.999	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.001	0.999	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.001	0.999	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.001	0.999	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.001	0.999	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.001	0.999	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations