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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs57681851
log Bayes Factor = 3.26619
Chromosome 4   position 2,290,698  (GRCh37) Explore rs57681851 on Ensembl!
Variant rs57681851 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.982 0.018 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.976 0.024 0.000
Chapter II Neoplasms
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.965 0.035 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.954 0.046 0.000
Z85 Personal history of malignant neoplasm
0.942 0.058 0.000
Chapter VII Diseases of the eye and adnexa
0.939 0.061 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.930 0.070 0.000
J40-J47 Chronic lower respiratory diseases
0.922 0.078 0.000
Chapter XIV Diseases of the genitourinary system
0.914 0.086 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.911 0.089 0.000
Z92 Personal history of medical treatment
0.909 0.091 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.902 0.098 0.000
L60-L75 Disorders of skin appendages
0.887 0.113 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.881 0.119 0.000
Chapter I Certain infectious and parasitic diseases
0.880 0.120 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.869 0.131 0.000
D10-D36 Benign neoplasms
0.864 0.136 0.000
J95-J99 Other diseases of the respiratory system
0.857 0.143 0.000
J30-J39 Other diseases of upper respiratory tract
0.856 0.144 0.000
J44 Other chronic obstructive pulmonary disease
0.854 0.146 0.000
Z90.7 Acquired absence of genital organ(s)
0.851 0.149 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.840 0.160 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.840 0.160 0.000
J90-J94 Other diseases of pleura
0.830 0.170 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.826 0.174 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.821 0.179 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.816 0.184 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.816 0.184 0.000
J00-J06 Acute upper respiratory infections
0.815 0.184 0.000
I49 Other cardiac arrhythmias
0.815 0.185 0.000
N83.2 Other and unspecified ovarian cysts
0.813 0.187 0.000
I26 Pulmonary embolism
0.809 0.191 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.807 0.193 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.803 0.197 0.000
I34 Nonrheumatic mitral valve disorders
0.799 0.201 0.000
N84 Polyp of female genital tract
0.797 0.203 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.792 0.208 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.791 0.209 0.000
C15-C26 Malignant neoplasms of digestive organs
0.790 0.210 0.000
L72.1 Trichilemmal cyst
0.788 0.212 0.000
I45 Other conduction disorders
0.788 0.212 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.786 0.214 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.784 0.216 0.000
I51 Complications and ill-defined descriptions of heart disease
0.783 0.217 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.780 0.220 0.000
H53-H54 Visual disturbances and blindness
0.779 0.221 0.000
Z80 Family history of malignant neoplasm
0.779 0.221 0.000
I44 Atrioventricular and left bundle-branch block
0.778 0.222 0.000
Z90.1 Acquired absence of breast(s)
0.777 0.223 0.000
D25 Leiomyoma of uterus
0.776 0.224 0.000
A00-A09 Intestinal infectious diseases
0.775 0.225 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.767 0.233 0.000
I46 Cardiac arrest
0.765 0.234 0.000
N87 Dysplasia of cervix uteri
0.765 0.234 0.000
L20-L30 Dermatitis and eczema
0.764 0.236 0.000
I05-I09 Chronic rheumatic heart diseases
0.763 0.237 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.762 0.238 0.000
T81 Complications of procedures, not elsewhere classified
0.760 0.240 0.000
J98 Other respiratory disorders
0.760 0.240 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.757 0.243 0.000
I50 Heart failure
0.756 0.244 0.000
C64-C68 Malignant neoplasms of urinary tract
0.754 0.246 0.000
Z90.5 Acquired absence of kidney
0.753 0.247 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.752 0.248 0.000
J43 Emphysema
0.748 0.251 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.748 0.252 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.746 0.254 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.745 0.255 0.000
I20-I25 Ischaemic heart diseases
0.743 0.257 0.000
N80 Endometriosis
0.741 0.259 0.000
H25-H28 Disorders of lens
0.740 0.260 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.740 0.260 0.000
N84.0 Polyp of corpus uteri
0.740 0.260 0.000
I31 Other diseases of pericardium
0.738 0.262 0.000
J47 Bronchiectasis
0.738 0.262 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.736 0.264 0.000
J09-J18 Influenza and pneumonia
0.735 0.265 0.000
J20-J22 Other acute lower respiratory infections
0.734 0.266 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.733 0.267 0.000
Z93 Artificial opening status
0.729 0.270 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.728 0.272 0.000
N88 Other noninflammatory disorders of cervix uteri
0.728 0.272 0.000
D00-D09 In situ neoplasms
0.727 0.273 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.721 0.278 0.000
I60-I69 Cerebrovascular diseases
0.720 0.279 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.720 0.280 0.000
D27 Benign neoplasm of ovary
0.719 0.281 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I47 Paroxysmal tachycardia
0.716 0.284 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.714 0.286 0.000
J90 Pleural effusion, not elsewhere classified
0.713 0.287 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.712 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.288 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.711 0.288 0.000
J60-J70 Lung diseases due to external agents
0.711 0.288 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.710 0.290 0.000
E00-E07 Disorders of thyroid gland
0.708 0.292 0.000
D17 Benign lipomatous neoplasm
0.706 0.294 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.706 0.294 0.000
H43-H45 Disorders of vitreous body and globe
0.706 0.294 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.704 0.295 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.704 0.296 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.703 0.297 0.000
D23 Other benign neoplasms of skin
0.701 0.299 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.701 0.299 0.000
Z97 Presence of other devices
0.700 0.300 0.000
Z94 Transplanted organ and tissue status
0.700 0.300 0.000
Z89 Acquired absence of limb
0.700 0.300 0.000
Z84 Family history of other conditions
0.700 0.300 0.000
Z83 Family history of other specific disorders
0.700 0.300 0.000
Z81 Family history of mental and behavioural disorders
0.700 0.300 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.699 0.301 0.000
Chapter XX External causes of morbidity and mortality
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.696 0.304 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.694 0.305 0.000
D25.9 Leiomyoma of uterus, unspecified
0.694 0.306 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.692 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.307 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.692 0.307 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.692 0.307 0.000
C51-C58 Malignant neoplasms of female genital organs
0.692 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.692 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.307 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.692 0.307 0.000
I52 Other heart disorders in diseases classified elsewhere
0.692 0.308 0.000
I48 Atrial fibrillation and flutter
0.692 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.692 0.308 0.000
I42 Cardiomyopathy
0.692 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.692 0.308 0.000
I40 Acute myocarditis
0.692 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.692 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.692 0.308 0.000
I30 Acute pericarditis
0.692 0.308 0.000
I38 Endocarditis, valve unspecified
0.692 0.308 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.692 0.308 0.000
A30-A49 Other bacterial diseases
0.691 0.309 0.000
E65-E68 Obesity and other hyperalimentation
0.687 0.313 0.000
N93 Other abnormal uterine and vaginal bleeding
0.685 0.315 0.000
L50-L54 Urticaria and erythema
0.684 0.316 0.000
L10-L14 Bullous disorders
0.684 0.316 0.000
N73 Other female pelvic inflammatory diseases
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.682 0.318 0.000
S60-S69 Injuries to the wrist and hand
0.681 0.319 0.000
I34.0 Mitral (valve) insufficiency
0.680 0.320 0.000
N83.1 Corpus luteum cyst
0.677 0.323 0.000
H40-H42 Glaucoma
0.676 0.324 0.000
I35 Nonrheumatic aortic valve disorders
0.676 0.324 0.000
C18 Malignant neoplasm of colon
0.676 0.324 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.675 0.324 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.675 0.324 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.675 0.324 0.000
Z85.6 Personal history of leukaemia
0.675 0.324 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.675 0.324 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.675 0.325 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.674 0.326 0.000
H55-H59 Other disorders of eye and adnexa
0.673 0.327 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.673 0.327 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.673 0.327 0.000
H10-H13 Disorders of conjunctiva
0.673 0.327 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.672 0.328 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.668 0.332 0.000
Z90.8 Acquired absence of other organs
0.667 0.333 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.667 0.333 0.000
Z90.3 Acquired absence of part of stomach
0.667 0.333 0.000
Z90.2 Acquired absence of lung [part of]
0.667 0.333 0.000
Z90.0 Acquired absence of part of head and neck
0.667 0.333 0.000
C79 Secondary malignant neoplasm of other sites
0.666 0.334 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.666 0.334 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.666 0.334 0.000
C34 Malignant neoplasm of bronchus and lung
0.666 0.334 0.000
J32 Chronic sinusitis
0.665 0.334 0.000
H52 Disorders of refraction and accommodation
0.665 0.335 0.000
J98.4 Other disorders of lung
0.665 0.335 0.000
H53 Visual disturbances
0.664 0.336 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.664 0.336 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.336 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.663 0.337 0.000
H30-H36 Disorders of choroid and retina
0.663 0.337 0.000
H26 Other cataract
0.661 0.339 0.000
J41 Simple and mucopurulent chronic bronchitis
0.661 0.339 0.000
J46 Status asthmaticus
0.661 0.339 0.000
J42 Unspecified chronic bronchitis
0.661 0.339 0.000
J40 Bronchitis, not specified as acute or chronic
0.661 0.339 0.000
I49.0 Ventricular fibrillation and flutter
0.661 0.339 0.000
I45.1 Other and unspecified right bundle-branch block
0.660 0.340 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.659 0.340 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.659 0.341 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.658 0.342 0.000
J34 Other disorders of nose and nasal sinuses
0.657 0.342 0.000
I51.7 Cardiomegaly
0.657 0.343 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.656 0.344 0.000
N99-N99 Other disorders of the genitourinary system
0.655 0.345 0.000
N00-N08 Glomerular diseases
0.655 0.345 0.000
I49.9 Cardiac arrhythmia, unspecified
0.655 0.345 0.000
N75 Diseases of Bartholin's gland
0.655 0.345 0.000
L72.0 Epidermal cyst
0.655 0.345 0.000
L40-L45 Papulosquamous disorders
0.654 0.346 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.653 0.347 0.000
T66-T78 Other and unspecified effects of external causes
0.653 0.347 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.653 0.347 0.000
T33-T35 Frostbite
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.653 0.347 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.653 0.347 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.347 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.653 0.347 0.000
T00-T07 Injuries involving multiple body regions
0.653 0.347 0.000
S90-S99 Injuries to the ankle and foot
0.653 0.347 0.000
S40-S49 Injuries to the shoulder and upper arm
0.653 0.347 0.000
S20-S29 Injuries to the thorax
0.653 0.347 0.000
S10-S19 Injuries to the neck
0.653 0.347 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.653 0.347 0.000
J02 Acute pharyngitis
0.652 0.347 0.000
Z92.9 Personal history of medical treatment, unspecified
0.652 0.348 0.000
Z92.8 Personal history of other medical treatment
0.652 0.348 0.000
Z92.5 Personal history of rehabilitation measures
0.652 0.348 0.000
Z92.0 Personal history of contraception
0.652 0.348 0.000
Z98 Other postsurgical states
0.651 0.349 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.651 0.349 0.000
N86 Erosion and ectropion of cervix uteri
0.649 0.350 0.000
N98 Complications associated with artificial fertilisation
0.646 0.353 0.000
N97 Female infertility
0.646 0.353 0.000
N91 Absent, scanty and rare menstruation
0.646 0.353 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.646 0.353 0.000
N89 Other noninflammatory disorders of vagina
0.646 0.353 0.000
N82 Fistulae involving female genital tract
0.646 0.353 0.000
N96 Habitual aborter
0.646 0.353 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.646 0.354 0.000
J33 Nasal polyp
0.643 0.357 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.643 0.357 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.639 0.361 0.000
N72 Inflammatory disease of cervix uteri
0.639 0.361 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.639 0.361 0.000
N87.0 Mild cervical dysplasia
0.638 0.362 0.000
N25-N29 Other disorders of kidney and ureter
0.638 0.362 0.000
L75 Apocrine sweat disorders
0.636 0.364 0.000
L74 Eccrine sweat disorders
0.636 0.364 0.000
L73 Other follicular disorders
0.636 0.364 0.000
L71 Rosacea
0.636 0.364 0.000
L70 Acne
0.636 0.364 0.000
L68 Hypertrichosis
0.636 0.364 0.000
L67 Hair colour and hair shaft abnormalities
0.636 0.364 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.636 0.364 0.000
L65 Other nonscarring hair loss
0.636 0.364 0.000
L64 Androgenic alopecia
0.636 0.364 0.000
L63 Alopecia areata
0.636 0.364 0.000
L62 Nail disorders in diseases classified elsewhere
0.636 0.364 0.000
L60 Nail disorders
0.636 0.364 0.000
J03 Acute tonsillitis
0.636 0.364 0.000
I28 Other diseases of pulmonary vessels
0.632 0.368 0.000
I27 Other pulmonary heart diseases
0.632 0.368 0.000
B35-B49 Mycoses
0.631 0.368 0.000
B99-B99 Other infectious diseases
0.631 0.369 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.631 0.369 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.631 0.369 0.000
B65-B83 Helminthiases
0.631 0.369 0.000
B50-B64 Protozoal diseases
0.631 0.369 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.631 0.369 0.000
B15-B19 Viral hepatitis
0.631 0.369 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.631 0.369 0.000
A80-A89 Viral infections of the central nervous system
0.631 0.369 0.000
A75-A79 Rickettsioses
0.631 0.369 0.000
A70-A74 Other diseases caused by chlamydiae
0.631 0.369 0.000
A65-A69 Other spirochaetal diseases
0.631 0.369 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.631 0.369 0.000
A20-A28 Certain zoonotic bacterial diseases
0.631 0.369 0.000
A15-A19 Tuberculosis
0.631 0.369 0.000
N10-N16 Renal tubulo-interstitial diseases
0.629 0.370 0.000
L30 Other dermatitis
0.628 0.372 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.628 0.372 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.625 0.374 0.000
J30 Vasomotor and allergic rhinitis
0.625 0.375 0.000
B95-B98 Bacterial, viral and other infectious agents
0.625 0.375 0.000
J43.9 Emphysema, unspecified
0.624 0.376 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.624 0.376 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.623 0.377 0.000
N83.7 Haematoma of broad ligament
0.623 0.377 0.000
N83.6 Haematosalpinx
0.623 0.377 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.623 0.377 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.623 0.377 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.623 0.377 0.000
N83.0 Follicular cyst of ovary
0.623 0.377 0.000
I46.0 Cardiac arrest with successful resuscitation
0.622 0.378 0.000
A04 Other bacterial intestinal infections
0.622 0.378 0.000
S80-S89 Injuries to the knee and lower leg
0.620 0.380 0.000
D36 Benign neoplasm of other and unspecified sites
0.619 0.381 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.619 0.381 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.619 0.381 0.000
D32 Benign neoplasm of meninges
0.619 0.381 0.000
D31 Benign neoplasm of eye and adnexa
0.619 0.381 0.000
D30 Benign neoplasm of urinary organs
0.619 0.381 0.000
D29 Benign neoplasm of male genital organs
0.619 0.381 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.619 0.381 0.000
D26 Other benign neoplasms of uterus
0.619 0.381 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.619 0.381 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.619 0.381 0.000
D19 Benign neoplasm of mesothelial tissue
0.619 0.381 0.000
D16 Benign neoplasm of bone and articular cartilage
0.619 0.381 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.619 0.381 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.619 0.381 0.000
D11 Benign neoplasm of major salivary glands
0.619 0.381 0.000
D10 Benign neoplasm of mouth and pharynx
0.619 0.381 0.000
D34 Benign neoplasm of thyroid gland
0.619 0.381 0.000
Z99.1 Dependence on respirator
0.617 0.383 0.000
Z92.3 Personal history of irradiation
0.616 0.384 0.000
Z87 Personal history of other diseases and conditions
0.615 0.385 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.614 0.385 0.000
J96 Respiratory failure, not elsewhere classified
0.614 0.385 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.614 0.385 0.000
S00-S09 Injuries to the head
0.614 0.386 0.000
J39 Other diseases of upper respiratory tract
0.613 0.386 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.613 0.386 0.000
J37 Chronic laryngitis and laryngotracheitis
0.613 0.386 0.000
J35 Chronic diseases of tonsils and adenoids
0.613 0.386 0.000
J36 Peritonsillar abscess
0.613 0.386 0.000
N17-N19 Renal failure
0.612 0.387 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.611 0.389 0.000
I44.0 Atrioventricular block, first degree
0.611 0.389 0.000
N92 Excessive, frequent and irregular menstruation
0.611 0.389 0.000
Z80.3 Family history of malignant neoplasm of breast
0.609 0.391 0.000
D25.0 Submucous leiomyoma of uterus
0.607 0.393 0.000
I08 Multiple valve diseases
0.605 0.395 0.000
I24 Other acute ischaemic heart diseases
0.603 0.397 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.603 0.397 0.000
N88.2 Stricture and stenosis of cervix uteri
0.603 0.397 0.000
N80.0 Endometriosis of uterus
0.603 0.397 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.602 0.398 0.000
T87 Complications peculiar to reattachment and amputation
0.602 0.398 0.000
T86 Failure and rejection of transplanted organs and tissues
0.602 0.398 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.602 0.398 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.602 0.398 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.602 0.398 0.000
L72.2 Steatocystoma multiplex
0.602 0.398 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.602 0.398 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.601 0.399 0.000
D18 Haemangioma and lymphangioma, any site
0.600 0.399 0.000
I44.7 Left bundle-branch block, unspecified
0.600 0.400 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.600 0.400 0.000
H00 Hordeolum and chalazion
0.599 0.400 0.000
Z95.1 Presence of aortocoronary bypass graft
0.596 0.404 0.000
D24 Benign neoplasm of breast
0.595 0.404 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.595 0.404 0.000
J94 Other pleural conditions
0.595 0.405 0.000
J93 Pneumothorax
0.595 0.405 0.000
J92 Pleural plaque
0.595 0.405 0.000
J91 Pleural effusion in conditions classified elsewhere
0.595 0.405 0.000
E66 Obesity
0.595 0.405 0.000
C80 Malignant neoplasm without specification of site
0.592 0.408 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.592 0.408 0.000
N73.6 Female pelvic peritoneal adhesions
0.589 0.411 0.000
C50-C50 Malignant neoplasm of breast
0.588 0.411 0.000
I50.9 Heart failure, unspecified
0.586 0.414 0.000
L08 Other local infections of skin and subcutaneous tissue
0.586 0.414 0.000
E50-E64 Other nutritional deficiencies
0.585 0.415 0.000
E40-E46 Malnutrition
0.585 0.415 0.000
E20-E35 Disorders of other endocrine glands
0.585 0.415 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.585 0.415 0.000
N76 Other inflammation of vagina and vulva
0.585 0.415 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.585 0.415 0.000
N71 Inflammatory disease of uterus, except cervix
0.585 0.415 0.000
N70 Salpingitis and oophoritis
0.585 0.415 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.585 0.415 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.585 0.415 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.585 0.415 0.000
J04 Acute laryngitis and tracheitis
0.585 0.415 0.000
J01 Acute sinusitis
0.585 0.415 0.000
J00 Acute nasopharyngitis [common cold]
0.585 0.415 0.000
I49.8 Other specified cardiac arrhythmias
0.585 0.415 0.000
I49.5 Sick sinus syndrome
0.585 0.415 0.000
I49.4 Other and unspecified premature depolarisation
0.585 0.415 0.000
I49.3 Ventricular premature depolarisation
0.585 0.415 0.000
I49.2 Junctional premature depolarisation
0.585 0.415 0.000
I49.1 Atrial premature depolarisation
0.585 0.415 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.583 0.417 0.000
H52.1 Myopia
0.583 0.417 0.000
Z88.0 Personal history of allergy to penicillin
0.583 0.417 0.000
Chapter V Mental and behavioural disorders
0.583 0.417 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.580 0.419 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.580 0.420 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.580 0.420 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.579 0.421 0.000
B25-B34 Other viral diseases
0.577 0.422 0.000
E03 Other hypothyroidism
0.577 0.422 0.000
Z22 Carrier of infectious disease
0.577 0.423 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.577 0.423 0.000
I31.3 Pericardial effusion (noninflammatory)
0.575 0.425 0.000
I22 Subsequent myocardial infarction
0.575 0.425 0.000
N94.1 Dyspareunia
0.574 0.426 0.000
H02 Other disorders of eyelid
0.574 0.426 0.000
D22 Melanocytic naevi
0.573 0.427 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.573 0.427 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.573 0.427 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.573 0.427 0.000
I34.1 Mitral (valve) prolapse
0.573 0.427 0.000
I50.1 Left ventricular failure
0.572 0.428 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.572 0.428 0.000
N84.9 Polyp of female genital tract, unspecified
0.572 0.428 0.000
N84.8 Polyp of other parts of female genital tract
0.572 0.428 0.000
N84.3 Polyp of vulva
0.572 0.428 0.000
N84.2 Polyp of vagina
0.572 0.428 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.572 0.428 0.000
N60-N64 Disorders of breast
0.571 0.428 0.000
C34.9 Bronchus or lung, unspecified
0.570 0.430 0.000
A08 Viral and other specified intestinal infections
0.570 0.430 0.000
H04 Disorders of lachrymal system
0.569 0.431 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.568 0.432 0.000
Z95.4 Presence of other heart-valve replacement
0.568 0.432 0.000
Z95.3 Presence of xenogenic heart valve
0.568 0.432 0.000
Z95.2 Presence of prosthetic heart valve
0.568 0.432 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.567 0.433 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.567 0.433 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.567 0.433 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.567 0.433 0.000
C32 Malignant neoplasm of larynx
0.567 0.433 0.000
C31 Malignant neoplasm of accessory sinuses
0.567 0.433 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.567 0.433 0.000
C37 Malignant neoplasm of thymus
0.567 0.433 0.000
C33 Malignant neoplasm of trachea
0.567 0.433 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.566 0.433 0.000
C25 Malignant neoplasm of pancreas
0.566 0.433 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.566 0.433 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.566 0.433 0.000
C21 Malignant neoplasm of anus and anal canal
0.566 0.433 0.000
C17 Malignant neoplasm of small intestine
0.566 0.433 0.000
C16 Malignant neoplasm of stomach
0.566 0.433 0.000
C15 Malignant neoplasm of oesophagus
0.566 0.433 0.000
C23 Malignant neoplasm of gallbladder
0.566 0.433 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.566 0.433 0.000
M20-M25 Other joint disorders
0.566 0.434 0.000
I45.9 Conduction disorder, unspecified
0.565 0.435 0.000
I45.8 Other specified conduction disorders
0.565 0.435 0.000
I45.6 Preexcitation syndrome
0.565 0.435 0.000
I45.5 Other specified heart block
0.565 0.435 0.000
I45.4 Nonspecific intraventricular block
0.565 0.435 0.000
I45.3 Trifascicular block
0.565 0.435 0.000
I45.2 Bifascicular block
0.565 0.435 0.000
I45.0 Right fascicular block
0.565 0.435 0.000
I21 Acute myocardial infarction
0.564 0.435 0.000
D50-D53 Nutritional anaemias
0.564 0.436 0.000
L05 Pilonidal cyst
0.562 0.438 0.000
L04 Acute lymphadenitis
0.562 0.438 0.000
L01 Impetigo
0.562 0.438 0.000
L00 Staphylococcal scalded skin syndrome
0.562 0.438 0.000
I51.9 Heart disease, unspecified
0.561 0.438 0.000
I51.6 Cardiovascular disease, unspecified
0.561 0.438 0.000
I51.5 Myocardial degeneration
0.561 0.438 0.000
I51.4 Myocarditis, unspecified
0.561 0.438 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.561 0.438 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.561 0.438 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.561 0.438 0.000
I51.0 Cardiac septal defect, acquired
0.561 0.438 0.000
D23.6 Skin of upper limb, including shoulder
0.561 0.439 0.000
E07 Other disorders of thyroid
0.561 0.439 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.560 0.440 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.560 0.440 0.000
H51 Other disorders of binocular movement
0.559 0.441 0.000
H50 Other strabismus
0.559 0.441 0.000
H49 Paralytic strabismus
0.559 0.441 0.000
H54 Blindness and low vision
0.558 0.441 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.558 0.442 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.558 0.442 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.558 0.442 0.000
Z80.6 Family history of leukaemia
0.558 0.442 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.558 0.442 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.558 0.442 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.558 0.442 0.000
I44.6 Other and unspecified fascicular block
0.558 0.442 0.000
I44.5 Left posterior fascicular block
0.558 0.442 0.000
I44.4 Left anterior fascicular block
0.558 0.442 0.000
I44.3 Other and unspecified atrioventricular block
0.558 0.442 0.000
I44.2 Atrioventricular block, complete
0.558 0.442 0.000
I44.1 Atrioventricular block, second degree
0.558 0.442 0.000
C18.7 Sigmoid colon
0.557 0.442 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.557 0.443 0.000
D25.2 Subserosal leiomyoma of uterus
0.556 0.444 0.000
D25.1 Intramural leiomyoma of uterus
0.556 0.444 0.000
A41 Other septicaemia
0.556 0.444 0.000
A07 Other protozoal intestinal diseases
0.556 0.444 0.000
A06 Amoebiasis
0.556 0.444 0.000
A05 Other bacterial foodborne intoxications
0.556 0.444 0.000
A03 Shigellosis
0.556 0.444 0.000
A02 Other Salmonella infections
0.556 0.444 0.000
A01 Typhoid and paratyphoid fevers
0.556 0.444 0.000
A00 Cholera
0.556 0.444 0.000
D05 Carcinoma in situ of breast
0.556 0.444 0.000
I51.8 Other ill-defined heart diseases
0.554 0.446 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.554 0.446 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.552 0.448 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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