TreeWAS – Variant ID: rs577272

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10.9 Without complications	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.998	0.002	0.000
K90 Intestinal malabsorption	0.996	0.004	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.006	0.994
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.014	0.986
E10.2 With renal complications	0.986	0.014	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.973	0.027	0.000
I10 Essential (primary) hypertension	0.000	0.030	0.970
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.030	0.970
B37.8 Candidiasis of other sites	0.961	0.039	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.050	0.950
K90.9 Intestinal malabsorption, unspecified	0.942	0.058	0.000
E14 Unspecified diabetes mellitus	0.930	0.070	0.000
B37 Candidiasis	0.927	0.073	0.000
Chapter VI Diseases of the nervous system	0.927	0.073	0.000
K90-K93 Other diseases of the digestive system	0.923	0.077	0.000
# Top node	0.920	0.080	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.918	0.082	0.000
Chapter XI Diseases of the digestive system	0.915	0.085	0.000
E10.1 With ketoacidosis	0.912	0.088	0.000
K70-K77 Diseases of liver	0.909	0.091	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.902	0.098	0.000
M06 Other rheumatoid arthritis	0.004	0.106	0.890
B37.9 Candidiasis, unspecified	0.894	0.106	0.000
K70 Alcoholic liver disease	0.885	0.115	0.000
B35-B49 Mycoses	0.876	0.124	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.125	0.875
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.125	0.875
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.129	0.871
E50-E64 Other nutritional deficiencies	0.869	0.131	0.000
Chapter I Certain infectious and parasitic diseases	0.867	0.133	0.000
L50-L54 Urticaria and erythema	0.867	0.133	0.000
L20-L30 Dermatitis and eczema	0.865	0.135	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.865	0.135	0.000
G37 Other demyelinating diseases of central nervous system	0.864	0.136	0.000
E27.1 Primary adrenocortical insufficiency	0.861	0.139	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.855	0.145	0.000
E20-E35 Disorders of other endocrine glands	0.854	0.146	0.000
E27 Other disorders of adrenal gland	0.847	0.153	0.000
K70.3 Alcoholic cirrhosis of liver	0.846	0.154	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.154	0.846
R26 Abnormalities of gait and mobility	0.843	0.157	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.843	0.157	0.000
E10.4 With neurological complications	0.840	0.160	0.000
L52 Erythema nodosum	0.837	0.163	0.000
K75 Other inflammatory liver diseases	0.836	0.164	0.000
D68 Other coagulation defects	0.834	0.166	0.000
E11 Non-insulin-dependent diabetes mellitus	0.831	0.169	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.826	0.174	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.176	0.824
K70.4 Alcoholic hepatic failure	0.821	0.179	0.000
E10.0 With coma	0.821	0.179	0.000
L10-L14 Bullous disorders	0.815	0.185	0.000
L40-L45 Papulosquamous disorders	0.813	0.187	0.000
L27 Dermatitis due to substances taken internally	0.812	0.188	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.812	0.188	0.000
K35-K38 Diseases of appendix	0.810	0.190	0.000
K73 Chronic hepatitis, not elsewhere classified	0.810	0.190	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.809	0.191	0.000
K75.4 Autoimmune hepatitis	0.809	0.191	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.807	0.193	0.000
L21 Seborrhoeic dermatitis	0.806	0.194	0.000
E14.1 With ketoacidosis	0.804	0.196	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.199	0.800
M05-M14 Inflammatory polyarthropathies	0.067	0.201	0.732
K90.8 Other intestinal malabsorption	0.798	0.202	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.798	0.202	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.796	0.204	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.792	0.208	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.209	0.791
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.210	0.790
M05 Seropositive rheumatoid arthritis	0.029	0.213	0.758
G30-G32 Other degenerative diseases of the nervous system	0.786	0.213	0.000
R26.3 Immobility	0.780	0.220	0.000
E10.6 With other specified complications	0.776	0.223	0.000
R21 Rash and other nonspecific skin eruption	0.775	0.225	0.000
E14.3 With ophthalmic complications	0.775	0.225	0.000
K70.9 Alcoholic liver disease, unspecified	0.769	0.231	0.000
E14.8 With unspecified complications	0.768	0.232	0.000
M06.3 Rheumatoid nodule	0.002	0.234	0.764
L21.9 Seborrhoeic dermatitis, unspecified	0.764	0.236	0.000
K75.8 Other specified inflammatory liver diseases	0.764	0.236	0.000
E14.6 With other specified complications	0.763	0.237	0.000
B25-B34 Other viral diseases	0.759	0.241	0.000
G90-G99 Other disorders of the nervous system	0.755	0.245	0.000
D68.5 Primary Thrombophilia	0.755	0.245	0.000
G96 Other disorders of central nervous system	0.753	0.247	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.752	0.248	0.000
L13 Other bullous disorders	0.752	0.248	0.000
E11.3 With ophthalmic complications	0.751	0.249	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.750	0.250	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.747	0.253	0.000
E14.5 With peripheral circulatory complications	0.747	0.253	0.000
E10.7 With multiple complications	0.743	0.257	0.000
K37 Unspecified appendicitis	0.741	0.259	0.000
E10.5 With peripheral circulatory complications	0.741	0.259	0.000
L40 Psoriasis	0.739	0.261	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.262	0.738
G96.0 Cerebrospinal fluid leak	0.737	0.263	0.000
R20 Disturbances of skin sensation	0.736	0.264	0.000
E11.1 With ketoacidosis	0.731	0.269	0.000
B25 Cytomegaloviral disease	0.729	0.271	0.000
E11.6 With other specified complications	0.726	0.274	0.000
L40.5 Arthropathic psoriasis	0.725	0.275	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.725	0.275	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.723	0.277	0.000
K74 Fibrosis and cirrhosis of liver	0.722	0.278	0.000
E70-E90 Metabolic disorders	0.721	0.279	0.000
E14.2 Withrenal complications	0.719	0.280	0.000
D68.0 Von Willebrand's disease	0.719	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.714	0.286	0.000
K90.3 Pancreatic steatorrhoea	0.714	0.286	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.714	0.286	0.000
K90.1 Tropical sprue	0.714	0.286	0.000
K73.9 Chronic hepatitis, unspecified	0.714	0.286	0.000
B25.9 Cytomegaloviral disease, unspecified	0.711	0.289	0.000
D68.9 Coagulation defect, unspecified	0.710	0.290	0.000
D68.6 Other Thrombophilia	0.708	0.292	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.708	0.292	0.000
L13.0 Dermatitis herpetiformis	0.707	0.293	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.707	0.293	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.702	0.298	0.000
B37.1 Pulmonary candidiasis	0.702	0.298	0.000
B37.2 Candidiasis of skin and nail	0.701	0.298	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.700	0.300	0.000
G70-G73 Diseases of myoneural junction and muscle	0.700	0.300	0.000
E89.0 Postprocedural hypothyroidism	0.698	0.302	0.000
B36 Other superficial mycoses	0.698	0.302	0.000
E51 Thiamine deficiency	0.697	0.303	0.000
E05.8 Other thyrotoxicosis	0.696	0.304	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.696	0.304	0.000
D55-D59 Haemolytic anaemias	0.695	0.305	0.000
K50-K52 Noninfective enteritis and colitis	0.693	0.307	0.000
E55 Vitamin D deficiency	0.692	0.308	0.000
L42 Pityriasis rosea	0.691	0.309	0.000
M06.34 Rheumatoid nodule (Hand)	0.001	0.309	0.690
K77 Liver disorders in diseases classified elsewhere	0.691	0.309	0.000
E28 Ovarian dysfunction	0.690	0.310	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.689	0.311	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.688	0.312	0.000
D66 Hereditary factor VIII deficiency	0.687	0.313	0.000
K38 Other diseases of appendix	0.686	0.314	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.314	0.686
B07 Viral warts	0.685	0.315	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.682	0.318	0.000
G36 Other acute disseminated demyelination	0.681	0.319	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.681	0.319	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.681	0.319	0.000
E11.5 With peripheral circulatory complications	0.679	0.321	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.679	0.321	0.000
K52 Other non-infective gastro-enteritis and colitis	0.678	0.322	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.678	0.322	0.000
E53 Deficiency of other B group vitamins	0.677	0.323	0.000
E63 Other nutritional deficiencies	0.676	0.324	0.000
A65-A69 Other spirochaetal diseases	0.676	0.324	0.000
G90 Disorders of autonomic nervous system	0.675	0.325	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.674	0.326	0.000
K74.6 Other and unspecified cirrhosis of liver	0.671	0.329	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.329	0.670
E14.7 With multiple complications	0.667	0.333	0.000
E14.0 With coma	0.667	0.333	0.000
M06.0 Seronegative rheumatoid arthritis	0.001	0.334	0.666
E14.4 With neurological complications	0.666	0.334	0.000
B37.6 Candidal endocarditis	0.665	0.335	0.000
B37.5 Candidal meningitis	0.665	0.335	0.000
E31 Polyglandular dysfunction	0.664	0.336	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.662	0.338	0.000
E73 Lactose intolerance	0.661	0.339	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.661	0.339	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.661	0.339	0.000
E24 Cushing's syndrome	0.657	0.343	0.000
L28 Lichen simplex chronicus and prurigo	0.656	0.344	0.000
D59 Acquired haemolytic anaemia	0.655	0.344	0.000
E40-E46 Malnutrition	0.655	0.345	0.000
L51 Erythema multiforme	0.653	0.347	0.000
E27.2 Addisonian crisis	0.653	0.347	0.000
E58 Dietary calcium deficiency	0.651	0.349	0.000
D68.2 Hereditary deficiency of other clotting factors	0.648	0.352	0.000
L26 Exfoliative dermatitis	0.647	0.353	0.000
B37.7 Candidal septicaemia	0.645	0.355	0.000
D68.8 Other specified coagulation defects	0.643	0.357	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.642	0.358	0.000
M06.2 Rheumatoid bursitis	0.003	0.359	0.638
M06.1 Adult-onset Still's disease	0.003	0.359	0.638
L23 Allergic contact dermatitis	0.638	0.362	0.000
K74.0 Hepatic fibrosis	0.637	0.362	0.000
L50 Urticaria	0.633	0.367	0.000
K76 Other diseases of liver	0.632	0.368	0.000
B48 Other mycoses, not elsewhere classified	0.628	0.372	0.000
B47 Mycetoma	0.628	0.372	0.000
B46 Zygomycosis	0.628	0.372	0.000
B45 Cryptococcosis	0.628	0.372	0.000
B43 Chromomycosis and phaeomycotic abscess	0.628	0.372	0.000
B42 Sporotrichosis	0.628	0.372	0.000
B41 Paracoccidioidomycosis	0.628	0.372	0.000
B40 Blastomycosis	0.628	0.372	0.000
B39 Histoplasmosis	0.628	0.372	0.000
B38 Coccidioidomycosis	0.628	0.372	0.000
L53 Other erythematous conditions	0.627	0.373	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.374	0.625
B37.4 Candidiasis of other urogenital sites	0.626	0.374	0.000
M06.8 Other specified rheumatoid arthritis	0.003	0.374	0.623
B85-B89 Pediculosis, acariasis and other infestations	0.626	0.374	0.000
L20 Atopic dermatitis	0.625	0.375	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.623	0.377	0.000
E50 Vitamin A deficiency	0.623	0.377	0.000
E60 Dietary zinc deficiency	0.623	0.377	0.000
E59 Dietary selenium deficiency	0.623	0.377	0.000
E54 Ascorbic acid deficiency	0.623	0.377	0.000
E52 Niacin deficiency [pellagra]	0.623	0.377	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.622	0.378	0.000
A75-A79 Rickettsioses	0.622	0.378	0.000
A70-A74 Other diseases caused by chlamydiae	0.622	0.378	0.000
L54 Erythema in diseases classified elsewhere	0.622	0.378	0.000
L24 Irritant contact dermatitis	0.620	0.379	0.000
L22 Diaper [napkin] dermatitis	0.620	0.379	0.000
G37.5 Concentric sclerosis [Balo]	0.620	0.380	0.000
G37.4 Subacute necrotising myelitis	0.620	0.380	0.000
G37.2 Central pontine myelinolysis	0.620	0.380	0.000
G37.1 Central demyelination of corpus callosum	0.620	0.380	0.000
G37.0 Diffuse sclerosis	0.620	0.380	0.000
Chapter XXII Codes for special purposes	0.619	0.381	0.000
E73.9 Lactose intolerance, unspecified	0.619	0.381	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.619	0.381	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.618	0.382	0.000
E32 Diseases of thymus	0.613	0.387	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.612	0.388	0.000
E30 Disorders of puberty, not elsewhere classified	0.612	0.388	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.612	0.388	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.612	0.388	0.000
E61 Deficiency of other nutrient elements	0.610	0.390	0.000
G62 Other polyneuropathies	0.610	0.390	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.609	0.391	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.608	0.392	0.000
E27.5 Adrenomedullary hyperfunction	0.608	0.392	0.000
E27.0 Other adrenocortical overactivity	0.608	0.392	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.607	0.393	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.607	0.393	0.000
L12 Pemphigoid	0.607	0.393	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.607	0.393	0.000
R26.1 Paralytic gait	0.604	0.395	0.000
E34 Other endocrine disorders	0.602	0.398	0.000
G96.9 Disorder of central nervous system, unspecified	0.601	0.399	0.000
K76.6 Portal hypertension	0.600	0.400	0.000
K75.2 Nonspecific reactive hepatitis	0.600	0.400	0.000
K75.1 Phlebitis of portal vein	0.600	0.400	0.000
E11.7 With multiple complications	0.599	0.400	0.000
L44 Other papulosquamous disorders	0.599	0.400	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.599	0.401	0.000
G59.0 Diabetic mononeuropathy	0.598	0.402	0.000
M08 Juvenile arthritis	0.046	0.406	0.548
K38.8 Other specified diseases of appendix	0.594	0.406	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.410	0.589
G62.9 Polyneuropathy, unspecified	0.590	0.410	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.589	0.410	0.000
E53.9 Vitamin B deficiency, unspecified	0.589	0.411	0.000
L25 Unspecified contact dermatitis	0.589	0.411	0.000
L40.1 Generalised pustular psoriasis	0.588	0.412	0.000
L10 Pemphigus	0.588	0.412	0.000
E11.4 With neurological complications	0.588	0.412	0.000
A20-A28 Certain zoonotic bacterial diseases	0.588	0.412	0.000
R20.1 Hypoaesthesia of skin	0.588	0.412	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.587	0.413	0.000
E06 Thyroiditis	0.585	0.415	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.001	0.415	0.583
L14 Bullous disorders in diseases classified elsewhere	0.584	0.416	0.000
E20 Hypoparathyroidism	0.584	0.416	0.000
E11.8 With unspecified complications	0.583	0.417	0.000
L41 Parapsoriasis	0.583	0.417	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.583	0.417	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.582	0.417	0.000
L27.8 Dermatitis due to other substances taken internally	0.582	0.417	0.000
E24.0 Pituitary-dependent Cushing's disease	0.582	0.418	0.000
E07 Other disorders of thyroid	0.582	0.418	0.000
R22.2 Localised swelling, mass and lump, trunk	0.581	0.419	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.581	0.419	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.581	0.419	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.581	0.419	0.000
M06.4 Inflammatory polyarthropathy	0.003	0.420	0.577
L21.8 Other seborrhoeic dermatitis	0.578	0.422	0.000
L21.1 Seborrhoeic infantile dermatitis	0.578	0.422	0.000
L21.0 Seborrhoea capitis	0.578	0.422	0.000
K36 Other appendicitis	0.577	0.423	0.000
G11 Hereditary ataxia	0.577	0.423	0.000
E88 Other metabolic disorders	0.577	0.423	0.000
R27 Other lack of coordination	0.575	0.425	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.425	0.573
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.425	0.573
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.425	0.573
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.425	0.573
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.425	0.573
R20.0 Anaesthesia of skin	0.574	0.426	0.000
E51.2 Wernicke's encephalopathy	0.573	0.427	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.048	0.427	0.525
E10.8 With unspecified complications	0.571	0.428	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.571	0.429	0.000
L40.3 Pustulosis palmaris et plantaris	0.571	0.429	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.570	0.430	0.000
B36.9 Superficial mycosis, unspecified	0.570	0.430	0.000
D69 Purpura and other haemorrhagic conditions	0.570	0.430	0.000
M05.2 Rheumatoid vasculitis	0.020	0.431	0.549
D50-D53 Nutritional anaemias	0.569	0.431	0.000
E55.9 Vitamin D deficiency, unspecified	0.565	0.435	0.000
E89.4 Postprocedural ovarian failure	0.565	0.435	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.021	0.436	0.543
M05.1 Rheumatoid lung disease	0.021	0.436	0.543
M05.0 Felty's syndrome	0.021	0.436	0.543
K71 Toxic liver disease	0.563	0.437	0.000
E13 Other specified diabetes mellitus	0.563	0.437	0.000
B49 Unspecified mycosis	0.562	0.437	0.000
G96.8 Other specified disorders of central nervous system	0.562	0.438	0.000
R30-R39 Symptoms and signs involving the urinary system	0.002	0.438	0.560
B37.0 Candidal stomatitis	0.560	0.440	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.001	0.440	0.558
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.558	0.442	0.000
L11 Other acantholytic disorders	0.557	0.442	0.000
G90.8 Other disorders of autonomic nervous system	0.557	0.443	0.000
L50.0 Allergic urticaria	0.557	0.443	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.553	0.447	0.000
D68.1 Hereditary factor XI deficiency	0.552	0.448	0.000
E25 Adrenogenital disorders	0.550	0.449	0.000
R26.0 Ataxic gait	0.550	0.450	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.001	0.451	0.548
M06.38 Rheumatoid nodule (Other)	0.001	0.451	0.548
M06.36 Rheumatoid nodule (Lower leg)	0.001	0.451	0.548
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.001	0.451	0.548
M06.33 Rheumatoid nodule (Forearm)	0.001	0.451	0.548
M06.31 Rheumatoid nodule (Shoulder region)	0.001	0.451	0.548
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.549	0.451	0.000
E83 Disorders of mineral metabolism	0.548	0.452	0.000
L53.0 Toxic erythema	0.546	0.454	0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.546	0.454	0.000
B30 Viral conjunctivitis	0.544	0.456	0.000
B26 Mumps	0.544	0.456	0.000
E28.2 Polycystic ovarian syndrome	0.543	0.457	0.000
G00 Bacterial meningitis, not elsewhere classified	0.543	0.457	0.000
E56 Other vitamin deficiencies	0.542	0.458	0.000
G92 Toxic encephalopathy	0.541	0.459	0.000
B99-B99 Other infectious diseases	0.540	0.460	0.000
E22 Hyperfunction of pituitary gland	0.540	0.460	0.000
A69 Other spirochaetal infections	0.539	0.460	0.000
L13.9 Bullous disorder, unspecified	0.539	0.461	0.000
L13.8 Other specified bullous disorders	0.539	0.461	0.000
L13.1 Subcorneal pustular dermatitis	0.539	0.461	0.000
E63.9 Nutritional deficiency, unspecified	0.538	0.461	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.537	0.463	0.000
D67 Hereditary factor IX deficiency	0.536	0.464	0.000
R33 Retention of urine	0.000	0.464	0.536
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.536	0.464	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.534	0.466	0.000
E28.3 Primary ovarian failure	0.534	0.466	0.000
K76.8 Other specified diseases of liver	0.533	0.467	0.000
D59.1 Other autoimmune haemolytic anaemias	0.532	0.468	0.000
L40.2 Acrodermatitis continua	0.530	0.470	0.000
M05.8 Other seropositive rheumatoid arthritis	0.022	0.471	0.507
G55.0 Nerve root and plexus compressions in neoplastic disease	0.529	0.471	0.000
M12 Other specific arthropathies	0.045	0.471	0.483
D68.4 Acquired coagulation factor deficiency	0.528	0.471	0.000
E31.0 Autoimmune polyglandular failure	0.528	0.472	0.000
G72 Other myopathies	0.527	0.473	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.474	0.526
B25.0 Cytomegaloviral pneumonitis	0.525	0.474	0.000
L12.0 Bullous pemphigoid	0.525	0.475	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.524	0.476	0.000
B25.2 Cytomegaloviral pancreatitis	0.523	0.477	0.000
B25.1 Cytomegaloviral hepatitis	0.523	0.477	0.000
L51.9 Erythema multiforme, unspecified	0.522	0.478	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.521	0.479	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.520	0.480	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.520	0.480	0.000
K74.1 Hepatic sclerosis	0.519	0.480	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.520	0.480	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.519	0.481	0.000
L30 Other dermatitis	0.519	0.481	0.000
K38.9 Disease of appendix, unspecified	0.518	0.482	0.000
K74.4 Secondary biliary cirrhosis	0.518	0.482	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.518	0.482	0.000
E77 Disorders of glycoprotein metabolism	0.517	0.483	0.000
E76 Disorders of glycosaminoglycan metabolism	0.517	0.483	0.000
E72 Other disorders of amino-acid metabolism	0.517	0.483	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.517	0.483	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.517	0.483	0.000
L28.0 Lichen simplex chronicus	0.517	0.483	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.484	0.516
E84 Cystic fibrosis	0.516	0.484	0.000
E61.2 Magnesium deficiency	0.515	0.485	0.000
R20.3 Hyperaesthesia	0.515	0.485	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.513	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.513	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.513	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.513	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.513	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.513	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.513	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.513	0.486	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.513	0.487	0.000
G11.9 Hereditary ataxia, unspecified	0.513	0.487	0.000
B06 Rubella [German measles]	0.512	0.488	0.000
B05 Measles	0.512	0.488	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.512	0.488	0.000
B04 Monkeypox	0.512	0.488	0.000
B03 Smallpox	0.512	0.488	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.511	0.489	0.000
G70 Myasthenia gravis and other myoneural disorders	0.511	0.489	0.000
G31.8 Other specified degenerative diseases of nervous system	0.510	0.490	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.510	0.490	0.000
B27 Infectious mononucleosis	0.509	0.491	0.000
L50.1 Idiopathic urticaria	0.509	0.491	0.000
B01 Varicella [chickenpox]	0.508	0.492	0.000
E15 Nondiabetic hypoglycaemic coma	0.507	0.493	0.000
E74 Other disorders of carbohydrate metabolism	0.507	0.493	0.000
K38.1 Appendicular concretions	0.506	0.494	0.000
E27.8 Other specified disorders of adrenal gland	0.505	0.495	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.504	0.496	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.503	0.496	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.503	0.496	0.000
E89.5 Postprocedural testicular hypofunction	0.503	0.496	0.000
E70 Disorders of aromatic amino-acid metabolism	0.501	0.499	0.000
B36.8 Other specified superficial mycoses	0.500	0.500	0.000
B36.3 Black piedra	0.500	0.500	0.000
B36.2 White piedra	0.500	0.500	0.000
B36.1 Tinea nigra	0.500	0.500	0.000
B36.0 Pityriasis versicolor	0.500	0.500	0.000
E51.9 Thiamine deficiency, unspecified	0.500	0.500	0.000
E51.8 Other manifestations of thiamine deficiency	0.500	0.500	0.000
E51.1 Beriberi	0.500	0.500	0.000
E85 Amyloidosis	0.499	0.501	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.499	0.501	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.498	0.502	0.000
D55 Anaemia due to enzyme disorders	0.498	0.502	0.000
E16 Other disorders of pancreatic internal secretion	0.498	0.502	0.000
E55.0 Rickets, active	0.496	0.504	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.496	0.504	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.504	0.495
D60-D64 Aplastic and other anaemias	0.496	0.504	0.000
B33 Other viral diseases, not elsewhere classified	0.495	0.504	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.495	0.505	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.495	0.505	0.000
E28.9 Ovarian dysfunction, unspecified	0.495	0.505	0.000
E28.8 Other ovarian dysfunction	0.495	0.505	0.000
E28.1 Androgen excess	0.495	0.505	0.000
E28.0 Oestrogen excess	0.495	0.505	0.000
B65-B83 Helminthiases	0.494	0.506	0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.494	0.506	0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.494	0.506	0.000
K38.3 Fistula of appendix	0.492	0.508	0.000
K38.0 Hyperplasia of appendix	0.492	0.508	0.000
E79 Disorders of purine and pyrimidine metabolism	0.490	0.510	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.490	0.510	0.000
G36.9 Acute disseminated demyelination, unspecified	0.488	0.511	0.000
G36.8 Other specified acute disseminated demyelination	0.488	0.511	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.488	0.511	0.000
R29.1 Meningismus	0.488	0.511	0.000
B90 Sequelae of tuberculosis	0.488	0.512	0.000
L89 Decubitus ulcer	0.487	0.513	0.000
K76.1 Chronic passive congestion of liver	0.487	0.513	0.000
B92 Sequelae of leprosy	0.487	0.513	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.486	0.514	0.000
E53.1 Pyridoxine deficiency	0.486	0.514	0.000
E53.0 Riboflavin deficiency	0.486	0.514	0.000
E63.8 Other specified nutritional deficiencies	0.485	0.515	0.000
E63.1 Imbalance of constituents of food intake	0.485	0.515	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.485	0.515	0.000
E83.5 Disorders of calcium metabolism	0.485	0.515	0.000
A68 Relapsing fevers	0.485	0.515	0.000
A67 Pinta [carate]	0.485	0.515	0.000
A66 Yaws	0.485	0.515	0.000
A65 Non-venereal syphilis	0.485	0.515	0.000
G90.4 Autonomic dysreflexia	0.484	0.516	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.484	0.516	0.000
E89.1 Postprocedural hypoinsulinaemia	0.484	0.516	0.000
L40.4 Guttate psoriasis	0.484	0.516	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations