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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs58495148
log Bayes Factor = 216.755
Chromosome 6   position 32,520,816  (GRCh37) Explore rs58495148 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
G37.9 Demyelinating disease of central nervous system, unspecified
0.999 0.001 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.003 0.997
H40-H42 Glaucoma
0.000 0.003 0.997
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.005 0.995
H40.9 Glaucoma, unspecified
0.000 0.005 0.995
H40 Glaucoma
0.000 0.005 0.995
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.000 0.006 0.994
I20-I25 Ischaemic heart diseases
0.000 0.007 0.993
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
I10-I15 Hypertensive diseases
0.000 0.009 0.991
J30-J39 Other diseases of upper respiratory tract
0.000 0.010 0.990
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.011 0.989
H43 Disorders of vitreous body
0.000 0.012 0.988
K70-K77 Diseases of liver
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.015 0.985
J44 Other chronic obstructive pulmonary disease
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.017 0.983
E70-E90 Metabolic disorders
0.000 0.020 0.980
E06 Thyroiditis
0.000 0.020 0.980
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.021 0.979
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.022 0.978
I20 Angina pectoris
0.000 0.023 0.977
I10 Essential (primary) hypertension
0.000 0.025 0.975
J33.8 Other polyp of sinus
0.000 0.026 0.974
E10.5 With peripheral circulatory complications
0.000 0.029 0.971
I22 Subsequent myocardial infarction
0.000 0.030 0.970
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.031 0.969
E05.9 Thyrotoxicosis, unspecified
0.000 0.031 0.969
K74 Fibrosis and cirrhosis of liver
0.000 0.032 0.968
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.033 0.967
E06.3 Autoimmune thyroiditis
0.000 0.034 0.966
E11.1 With ketoacidosis
0.000 0.035 0.965
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.035 0.965
H43.8 Other disorders of vitreous body
0.000 0.037 0.963
K51.8 Other ulcerative colitis
0.961 0.039 0.000
E11.3 With ophthalmic complications
0.000 0.041 0.959
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.043 0.957
H43.3 Other vitreous opacities
0.000 0.049 0.951
J86 Pyothorax
0.000 0.049 0.951
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.056 0.944
I12 Hypertensive renal disease
0.000 0.058 0.942
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.061 0.939
K55-K64 Other diseases of intestines
0.000 0.063 0.937
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.064 0.936
K82 Other diseases of gallbladder
0.000 0.065 0.935
H34 Retinal vascular occlusions
0.000 0.066 0.934
E10.2 With renal complications
0.000 0.067 0.933
I20.9 Angina pectoris, unspecified
0.000 0.068 0.932
K82.8 Other specified diseases of gallbladder
0.000 0.068 0.932
K74.3 Primary biliary cirrhosis
0.000 0.069 0.931
J46 Status asthmaticus
0.000 0.072 0.928
J33.0 Polyp of nasal cavity
0.000 0.078 0.922
J86.9 Pyothorax without fistula
0.000 0.081 0.919
M06.0 Seronegative rheumatoid arthritis
0.000 0.086 0.914
K50-K52 Noninfective enteritis and colitis
0.022 0.087 0.891
K51.2 Ulcerative (chronic) proctitis
0.911 0.089 0.000
M65-M68 Disorders of synovium and tendon
0.000 0.096 0.904
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.096 0.904
K63 Other diseases of intestine
0.000 0.096 0.904
E11.5 With peripheral circulatory complications
0.000 0.098 0.902
I20.1 Angina pectoris with documented spasm
0.000 0.098 0.902
I20.0 Unstable angina
0.000 0.099 0.901
K60 Fissure and fistula of anal and rectal regions
0.000 0.099 0.901
J43 Emphysema
0.000 0.101 0.899
K75 Other inflammatory liver diseases
0.000 0.103 0.897
K58 Irritable bowel syndrome
0.000 0.104 0.896
K72 Hepatic failure, not elsewhere classified
0.000 0.107 0.893
E03.8 Other specified hypothyroidism
0.000 0.111 0.889
K63.9 Disease of intestine, unspecified
0.000 0.115 0.885
E11.2 With renal complications
0.000 0.115 0.885
L43.9 Lichen planus, unspecified
0.000 0.116 0.884
L43 Lichen planus
0.000 0.116 0.884
L40-L45 Papulosquamous disorders
0.000 0.117 0.883
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.118 0.882
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.118 0.882
H40.1 Primary open-angle glaucoma
0.000 0.120 0.880
E11.6 With other specified complications
0.000 0.122 0.878
I25 Chronic ischaemic heart disease
0.000 0.122 0.878
M06.4 Inflammatory polyarthropathy
0.000 0.128 0.872
M07 Psoriatic and enteropathic arthropathies
0.000 0.130 0.870
E13 Other specified diabetes mellitus
0.000 0.131 0.869
L40 Psoriasis
0.000 0.132 0.868
K75.4 Autoimmune hepatitis
0.000 0.137 0.863
I12.9 Hypertensive renal disease without renal failure
0.000 0.139 0.861
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.143 0.857
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.143 0.856
L40.5 Arthropathic psoriasis
0.000 0.144 0.856
K63.3 Ulcer of intestine
0.000 0.147 0.853
M65 Synovitis and tenosynovitis
0.000 0.148 0.852
E07 Other disorders of thyroid
0.000 0.150 0.850
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.849 0.151 0.000
I15 Secondary hypertension
0.000 0.157 0.843
J86.0 Pyothorax with fistula
0.000 0.164 0.836
K60.0 Acute anal fissure
0.000 0.167 0.833
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.170 0.830
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.171 0.829
G37.8 Other specified demyelinating diseases of central nervous system
0.828 0.172 0.000
H34.8 Other retinal vascular occlusions
0.000 0.174 0.826
K82.1 Hydrops of gallbladder
0.000 0.175 0.825
I12.0 Hypertensive renal disease with renal failure
0.000 0.177 0.823
M06.3 Rheumatoid nodule
0.000 0.178 0.822
K60.2 Anal fissure, unspecified
0.000 0.178 0.822
K50 Crohn's disease [regional enteritis]
0.001 0.179 0.820
K74.5 Biliary cirrhosis, unspecified
0.000 0.180 0.820
K51.4 Pseudopolyposis of colon
0.819 0.181 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.184 0.816
K74.6 Other and unspecified cirrhosis of liver
0.000 0.185 0.815
I25.5 Ischaemic cardiomyopathy
0.000 0.186 0.814
K86 Other diseases of pancreas
0.000 0.188 0.812
K60.5 Anorectal fistula
0.000 0.194 0.806
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.196 0.804
H40.5 Glaucoma secondary to other eye disorders
0.000 0.197 0.803
J37 Chronic laryngitis and laryngotracheitis
0.000 0.201 0.799
J43.9 Emphysema, unspecified
0.000 0.203 0.797
M14 Arthropathies in other diseases classified elsewhere
0.000 0.203 0.796
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.204 0.796
J95-J99 Other diseases of the respiratory system
0.000 0.207 0.793
K51.5 Mucosal proctocolitis
0.790 0.210 0.000
E16.1 Other hypoglycaemia
0.000 0.210 0.790
I24 Other acute ischaemic heart diseases
0.000 0.213 0.787
J32 Chronic sinusitis
0.000 0.214 0.786
E88 Other metabolic disorders
0.000 0.219 0.781
E11.4 With neurological complications
0.000 0.220 0.780
K90.9 Intestinal malabsorption, unspecified
0.000 0.221 0.779
M07.3 Other psoriatic arthropathies
0.000 0.223 0.777
E78.2 Mixed hyperlipidaemia
0.000 0.224 0.776
Chapter VIII Diseases of the ear and mastoid process
0.000 0.224 0.776
E13.9 Without complications
0.000 0.225 0.775
K72.9 Hepatic failure, unspecified
0.000 0.228 0.772
K73 Chronic hepatitis, not elsewhere classified
0.000 0.229 0.771
E78.1 Pure hyperglyceridaemia
0.000 0.229 0.771
E11.0 With coma
0.000 0.232 0.768
E40-E46 Malnutrition
0.000 0.235 0.765
M11 Other crystal arthropathies
0.000 0.236 0.764
H34.2 Other retinal artery occlusions
0.000 0.236 0.764
K63.4 Enteroptosis
0.000 0.238 0.762
H34.1 Central retinal artery occlusion
0.000 0.238 0.762
K55 Vascular disorders of intestine
0.000 0.239 0.761
H60-H62 Diseases of external ear
0.000 0.239 0.761
E07.9 Disorder of thyroid, unspecified
0.000 0.242 0.758
H43.1 Vitreous haemorrhage
0.000 0.243 0.757
M70-M79 Other soft tissue disorders
0.000 0.246 0.754
K72.0 Acute and subacute hepatic failure
0.000 0.247 0.753
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.249 0.751
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.250 0.750
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.251 0.749
H61 Other disorders of external ear
0.000 0.254 0.746
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.255 0.745
H43.9 Disorder of vitreous body, unspecified
0.000 0.260 0.740
H30 Chorioretinal inflammation
0.000 0.261 0.739
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.261 0.739
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.261 0.739
I25.2 Old myocardial infarction
0.000 0.263 0.737
K86.2 Cyst of pancreas
0.000 0.265 0.735
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.271 0.729
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.272 0.728
K82.9 Disease of gallbladder, unspecified
0.000 0.272 0.728
K50.8 Other Crohn's disease
0.000 0.274 0.726
H43.2 Crystalline deposits in vitreous body
0.000 0.275 0.725
J43.2 Centrilobular emphysema
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
J33.1 Polypoid sinus degeneration
0.000 0.284 0.716
K50.1 Crohn's disease of large intestine
0.000 0.284 0.716
E11.8 With unspecified complications
0.000 0.285 0.715
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.285 0.715
H42 Glaucoma in diseases classified elsewhere
0.000 0.285 0.715
L43.8 Other lichen planus
0.000 0.286 0.714
E74 Other disorders of carbohydrate metabolism
0.000 0.286 0.714
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.287 0.713
H40.6 Glaucoma secondary to drugs
0.000 0.287 0.713
H40.4 Glaucoma secondary to eye inflammation
0.000 0.287 0.713
H40.3 Glaucoma secondary to eye trauma
0.000 0.287 0.713
I00-I02 Acute rheumatic fever
0.000 0.288 0.712
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.711
I13 Hypertensive heart and renal disease
0.000 0.289 0.711
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.290 0.710
H61.0 Perichondritis of external ear
0.000 0.290 0.710
H43.0 Vitreous prolapse
0.000 0.291 0.709
K77 Liver disorders in diseases classified elsewhere
0.000 0.292 0.708
K71 Toxic liver disease
0.000 0.292 0.708
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.295 0.705
E78.6 Lipoprotein deficiency
0.000 0.295 0.705
E78.3 Hyperchylomicronaemia
0.000 0.295 0.705
I23 Certain current complications following acute myocardial infarction
0.000 0.295 0.705
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.295 0.705
E77 Disorders of glycoprotein metabolism
0.000 0.297 0.703
E76 Disorders of glycosaminoglycan metabolism
0.000 0.297 0.703
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.297 0.703
E72 Other disorders of amino-acid metabolism
0.000 0.297 0.703
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.297 0.703
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.297 0.703
E06.5 Other chronic thyroiditis
0.000 0.297 0.702
E06.4 Drug-induced thyroiditis
0.000 0.297 0.702
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.297 0.702
E06.1 Subacute thyroiditis
0.000 0.297 0.702
E06.0 Acute thyroiditis
0.000 0.297 0.702
E05.5 Thyroid crisis or storm
0.000 0.298 0.702
E05.4 Thyrotoxicosis factitia
0.000 0.298 0.702
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.298 0.702
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.298 0.702
M14.6 Neuropathic arthropathy
0.000 0.299 0.701
K82.2 Perforation of gallbladder
0.000 0.301 0.699
I15.1 Hypertension secondary to other renal disorders
0.000 0.303 0.697
J98 Other respiratory disorders
0.000 0.303 0.697
E06.9 Thyroiditis, unspecified
0.000 0.305 0.695
K74.4 Secondary biliary cirrhosis
0.000 0.306 0.694
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.306 0.694
K74.1 Hepatic sclerosis
0.000 0.306 0.694
E83 Disorders of mineral metabolism
0.566 0.307 0.127
E78.5 Hyperlipidaemia, unspecified
0.000 0.309 0.691
K86.3 Pseudocyst of pancreas
0.000 0.314 0.686
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.314 0.686
L40.9 Psoriasis, unspecified
0.000 0.314 0.686
M66 Spontaneous rupture of synovium and tendon
0.000 0.317 0.682
K63.2 Fistula of intestine
0.000 0.318 0.682
M75 Shoulder lesions
0.000 0.319 0.681
J41 Simple and mucopurulent chronic bronchitis
0.000 0.322 0.678
K51.0 Ulcerative (chronic) enterocolitis
0.675 0.325 0.000
M77 Other enthesopathies
0.000 0.325 0.675
K52 Other non-infective gastro-enteritis and colitis
0.003 0.325 0.671
M12 Other specific arthropathies
0.000 0.326 0.674
J32.4 Chronic pansinusitis
0.000 0.326 0.673
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.327 0.673
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.328 0.672
I11 Hypertensive heart disease
0.000 0.329 0.671
H34.0 Transient retinal artery occlusion
0.000 0.330 0.669
I15.9 Seconday hypertension, unspecified
0.000 0.331 0.669
K82.3 Fistula of gallbladder
0.000 0.335 0.665
I25.1 Atherosclerotic heart disease
0.000 0.335 0.665
J98.4 Other disorders of lung
0.000 0.336 0.664
K75.9 Inflammatory liver disease, unspecified
0.000 0.337 0.663
J37.0 Chronic laryngitis
0.000 0.337 0.663
M77.1 Lateral epicondylitis
0.000 0.340 0.660
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.340 0.660
M06.34 Rheumatoid nodule (Hand)
0.000 0.341 0.658
M75.0 Adhesive capsulitis of shoulder
0.000 0.342 0.658
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.342 0.658
H34.9 Retinal vascular occlusion, unspecified
0.000 0.343 0.657
E84 Cystic fibrosis
0.000 0.344 0.656
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.344 0.655
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.344 0.655
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.344 0.655
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.344 0.655
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.344 0.655
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.344 0.655
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.344 0.655
M65.1 Other infective (teno)synovitis
0.000 0.345 0.655
K81 Cholecystitis
0.000 0.347 0.653
J42 Unspecified chronic bronchitis
0.000 0.347 0.653
J85 Abscess of lung and mediastinum
0.000 0.349 0.651
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.349 0.651
J32.9 Chronic sinusitis, unspecified
0.000 0.350 0.650
H61.8 Other specified disorders of external ear
0.000 0.351 0.649
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.352 0.648
K55.8 Other vascular disorders of intestine
0.000 0.353 0.647
M45-M49 Spondylopathies
0.000 0.354 0.646
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.354 0.646
K55.2 Angiodysplasia of colon
0.000 0.355 0.645
H61.1 Non-infective disorders of pinna
0.000 0.355 0.645
J43.8 Other emphysema
0.000 0.355 0.645
J43.1 Panlobular emphysema
0.000 0.355 0.645
J43.0 MacLeod's syndrome
0.000 0.355 0.645
I25.4 Coronary artery aneurysm
0.000 0.355 0.644
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.357 0.643
K75.2 Nonspecific reactive hepatitis
0.000 0.357 0.643
K75.1 Phlebitis of portal vein
0.000 0.357 0.643
K86.1 Other chronic pancreatitis
0.000 0.358 0.642
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.358 0.641
K72.1 Chronic hepatic failure
0.000 0.359 0.640
K82.0 Obstruction of gallbladder
0.000 0.360 0.640
H25-H28 Disorders of lens
0.000 0.361 0.639
M35.3 Polymyalgia rheumatica
0.000 0.361 0.639
M20-M25 Other joint disorders
0.000 0.362 0.638
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.364 0.636
K74.0 Hepatic fibrosis
0.000 0.364 0.636
E79 Disorders of purine and pyrimidine metabolism
0.000 0.366 0.633
L43.3 Subacute (active) lichen planus
0.000 0.366 0.633
L43.2 Lichenoid drug reaction
0.000 0.366 0.633
L43.1 Bullous lichen planus
0.000 0.366 0.633
L43.0 Hypertrophic lichen planus
0.000 0.366 0.633
L44 Other papulosquamous disorders
0.000 0.367 0.633
L41 Parapsoriasis
0.000 0.367 0.633
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.367 0.633
M35 Other systemic involvement of connective tissue
0.000 0.368 0.632
M10 Gout
0.000 0.368 0.631
K50.0 Crohn's disease of small intestine
0.000 0.370 0.630
I25.6 Silent myocardial ischaemia
0.000 0.371 0.629
I25.3 Aneurysm of heart
0.000 0.371 0.629
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.374 0.626
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.374 0.626
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.374 0.626
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.374 0.626
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.374 0.626
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.374 0.626
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.374 0.626
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.374 0.626
M07.6 Other enteropathic arthropathies
0.000 0.376 0.624
M07.5 Arthropathy in ulcerative colitis
0.000 0.376 0.624
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.376 0.624
M07.2 Psoriatic spondylitis
0.000 0.376 0.624
M07.1 Arthritis mutilans
0.000 0.376 0.624
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.376 0.624
M45 Ankylosing spondylitis
0.000 0.376 0.624
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.377 0.623
E13.8 With unspecified complications
0.000 0.377 0.623
E13.7 With multiple complications
0.000 0.377 0.623
E13.6 With other specified complications
0.000 0.377 0.623
E13.5 With peripheral circulatory complications
0.000 0.377 0.623
E13.4 With neurological complications
0.000 0.377 0.623
E13.3 With ophthalmic complications
0.000 0.377 0.623
E13.2 With renal complications
0.000 0.377 0.623
E13.1 With ketoacidosis
0.000 0.377 0.623
E13.0 With coma
0.000 0.377 0.623
L40.4 Guttate psoriasis
0.000 0.377 0.623
L40.3 Pustulosis palmaris et plantaris
0.000 0.377 0.623
L40.2 Acrodermatitis continua
0.000 0.377 0.623
L40.1 Generalised pustular psoriasis
0.000 0.377 0.623
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.379 0.621
E05.8 Other thyrotoxicosis
0.000 0.379 0.621
I85 Oesophageal varices
0.000 0.381 0.619
L40.8 Other psoriasis
0.000 0.381 0.619
M75.2 Bicipital tendinitis
0.000 0.382 0.618
K90.8 Other intestinal malabsorption
0.000 0.383 0.616
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.389 0.611
M65.2 Calcific tendinitis
0.000 0.389 0.611
M65.0 Abscess of tendon sheath
0.000 0.389 0.611
K52.1 Toxic gastro-enteritis and colitis
0.001 0.391 0.608
E07.1 Dyshormogenetic goitre
0.000 0.391 0.609
E07.0 Hypersecretion of calcitonin
0.000 0.391 0.609
E88.2 Lipomatosis, not elsewhere classified
0.000 0.392 0.608
H60 Otitis externa
0.000 0.393 0.607
I15.8 Other secondary hypertension
0.000 0.395 0.604
I15.2 Hypertension secondary to endocrine disorders
0.000 0.395 0.604
I15.0 Renovascular hypertension
0.000 0.395 0.604
K60.4 Rectal fistula
0.000 0.395 0.604
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.398 0.602
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.399 0.600
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.400 0.600
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.402 0.598
E73 Lactose intolerance
0.000 0.402 0.597
E46 Unspecified protein-energy malnutrition
0.000 0.403 0.597
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.404 0.596
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.405 0.595
M11.2 Other chondrocalcinosis
0.000 0.405 0.595
K73.9 Chronic hepatitis, unspecified
0.000 0.406 0.594
K91.3 Postoperative intestinal obstruction
0.000 0.408 0.592
L40.0 Psoriasis vulgaris
0.000 0.409 0.591
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.410 0.590
M06.38 Rheumatoid nodule (Other)
0.000 0.410 0.590
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.410 0.590
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.410 0.590
M06.33 Rheumatoid nodule (Forearm)
0.000 0.410 0.590
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.410 0.590
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.410 0.590
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.410 0.590
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.411 0.589
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.412 0.587
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.415 0.585
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.415 0.585
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.415 0.585
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.415 0.585
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.415 0.585
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.415 0.585
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.415 0.585
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.415 0.585
M00-M03 Infectious arthropathies
0.000 0.415 0.585
I85.9 Oesophageal varices without bleeding
0.000 0.418 0.582
K75.8 Other specified inflammatory liver diseases
0.000 0.418 0.582
K55.1 Chronic vascular disorders of intestine
0.000 0.418 0.582
M60-M63 Disorders of muscles
0.000 0.419 0.581
J60-J70 Lung diseases due to external agents
0.000 0.419 0.581
J31.2 Chronic pharyngitis
0.000 0.419 0.581
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.419 0.581
M24 Other specific joint derangements
0.000 0.424 0.576
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.425 0.575
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.425 0.575
L10-L14 Bullous disorders
0.000 0.427 0.573
J37.1 Chronic laryngotracheitis
0.000 0.427 0.573
H27 Other disorders of lens
0.000 0.428 0.572
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.429 0.571
M14.4 Arthropathy in amyloidosis
0.000 0.429 0.571
M14.3 Lipoid dermatoarthritis
0.000 0.429 0.571
M14.2 Diabetic arthropathy
0.000 0.429 0.571
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.429 0.571
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.429 0.571
H61.3 Acquired stenosis of external ear canal
0.000 0.429 0.571
J32.1 Chronic frontal sinusitis
0.000 0.430 0.570
J32.2 Chronic ethmoidal sinusitis
0.000 0.430 0.570
J96 Respiratory failure, not elsewhere classified
0.000 0.431 0.569
I86 Varicose veins of other sites
0.000 0.433 0.567
M24.1 Other articular cartilage disorders
0.000 0.434 0.566

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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