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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs58727484
log Bayes Factor = 13.4119
Chromosome 1   position 219,748,784  (GRCh37) Explore rs58727484 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K42.9 Umbilical hernia without obstruction or gangrene
1.000 0.000 0.000
K40-K46 Hernia
1.000 0.000 0.000
K42 Umbilical hernia
1.000 0.000 0.000
K43.9 Ventral hernia without obstruction or gangrene
1.000 0.000 0.000
K43 Ventral hernia
1.000 0.000 0.000
K41 Femoral hernia
1.000 0.000 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.999 0.001 0.000
K40 Inguinal hernia
0.971 0.029 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.960 0.040 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.959 0.041 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.913 0.087 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.790 0.210 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.744 0.256 0.000
K42.1 Umbilical hernia with gangrene
0.717 0.283 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.717 0.283 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.717 0.283 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.717 0.283 0.000
K43.4 Parastomal hernia with gangrene
0.717 0.283 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.717 0.283 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.717 0.283 0.000
K43.1 Ventral hernia with gangrene
0.717 0.283 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.717 0.283 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.717 0.283 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.717 0.283 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.717 0.283 0.000
K45 Other abdominal hernia
0.712 0.288 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.696 0.303 0.000
K46 Unspecified abdominal hernia
0.638 0.362 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.624 0.376 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.582 0.417 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.524 0.476 0.000
K45.1 Other specified abdominal hernia with gangrene
0.510 0.489 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.463 0.537 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.457 0.543 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.457 0.543 0.000
K44 Diaphragmatic hernia
0.427 0.573 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.390 0.609 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.378 0.622 0.000
K44.1 Diaphragmatic hernia with gangrene
0.306 0.694 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.301 0.699 0.000
N81.4 Uterovaginal prolapse, unspecified
0.000 0.846 0.154
M16.9 Coxarthrosis, unspecified
0.083 0.917 0.000
M16 Coxarthrosis [arthrosis of hip]
0.083 0.917 0.000
M16.1 Other primary coxarthrosis
0.078 0.922 0.000
M16.7 Other secondary coxarthrosis
0.078 0.922 0.000
M16.0 Primary coxarthrosis, bilateral
0.073 0.927 0.000
M16.5 Other posttraumatic coxarthrosis
0.062 0.938 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.062 0.938 0.000
M16.3 Other dysplastic coxarthrosis
0.061 0.939 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.060 0.940 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.060 0.940 0.000
I42.0 Dilated cardiomyopathy
0.058 0.942 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.947 0.053
E10.3 With ophthalmic complications
0.000 0.948 0.052
E10.9 Without complications
0.000 0.949 0.051
I35.0 Aortic (valve) stenosis
0.050 0.950 0.000
I50 Heart failure
0.050 0.950 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.950 0.050
I50.0 Congestive heart failure
0.050 0.950 0.000
I50.9 Heart failure, unspecified
0.049 0.951 0.000
E11.4 With neurological complications
0.000 0.951 0.049
I42 Cardiomyopathy
0.049 0.951 0.000
E11.3 With ophthalmic complications
0.000 0.952 0.048
E10-E14 Diabetes mellitus
0.000 0.953 0.047
I42.8 Other cardiomyopathies
0.045 0.955 0.000
I50.1 Left ventricular failure
0.044 0.956 0.000
I42.6 Alcoholic cardiomyopathy
0.042 0.958 0.000
I35 Nonrheumatic aortic valve disorders
0.042 0.958 0.000
E10.5 With peripheral circulatory complications
0.000 0.959 0.041
E10.2 With renal complications
0.000 0.959 0.041
E11.5 With peripheral circulatory complications
0.000 0.960 0.040
E11.0 With coma
0.000 0.960 0.039
I42.9 Cardiomyopathy, unspecified
0.039 0.961 0.000
E10.6 With other specified complications
0.000 0.961 0.039
E10.8 With unspecified complications
0.000 0.961 0.039
I35.2 Aortic (valve) stenosis with insufficiency
0.039 0.961 0.000
E10.4 With neurological complications
0.000 0.962 0.038
E11.1 With ketoacidosis
0.000 0.962 0.038
E10.7 With multiple complications
0.000 0.962 0.038
E11.7 With multiple complications
0.000 0.964 0.036
I42.7 Cardiomyopathy due to drugs and other external agents
0.035 0.964 0.000
I42.5 Other restrictive cardiomyopathy
0.035 0.964 0.000
I42.4 Endocardial fibroelastosis
0.035 0.964 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.035 0.964 0.000
E11.9 Without complications
0.000 0.965 0.035
E12 Malnutrition-related diabetes mellitus
0.000 0.966 0.034
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.033 0.967 0.000
I35.8 Other aortic valve disorders
0.033 0.967 0.000
E10.1 With ketoacidosis
0.000 0.967 0.033
E10.0 With coma
0.000 0.967 0.033
E11.8 With unspecified complications
0.000 0.967 0.033
I30-I52 Other forms of heart disease
0.032 0.968 0.000
H36.0 Diabetic retinopathy
0.000 0.968 0.032
E13 Other specified diabetes mellitus
0.000 0.968 0.032
I42.1 Obstructive hypertrophic cardiomyopathy
0.031 0.969 0.000
E11.2 With renal complications
0.000 0.969 0.031
E14 Unspecified diabetes mellitus
0.000 0.970 0.030
I35.9 Aortic valve disorder, unspecified
0.029 0.971 0.000
S72.00 Fracture of neck of femur (closed)
0.000 0.972 0.028
I30 Acute pericarditis
0.027 0.972 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.973 0.027
E14.3 With ophthalmic complications
0.000 0.974 0.026
I43 Cardiomyopathy in diseases classified elsewhere
0.025 0.975 0.000
E12.9 Without complications
0.000 0.975 0.025
E12.8 With unspecified complications
0.000 0.975 0.025
E12.7 With multiple complications
0.000 0.975 0.025
E12.6 With other specified complications
0.000 0.975 0.025
E12.5 With peripheral circulatory complications
0.000 0.975 0.025
E12.4 With neurological complications
0.000 0.975 0.025
E12.3 With ophthalmic complications
0.000 0.975 0.025
E12.2 With renal complications
0.000 0.975 0.025
E12.1 With ketoacidosis
0.000 0.975 0.025
E12.0 With coma
0.000 0.975 0.025
I30.9 Acute pericarditis, unspecified
0.025 0.975 0.000
I52 Other heart disorders in diseases classified elsewhere
0.023 0.977 0.000
I48 Atrial fibrillation and flutter
0.023 0.977 0.000
I41 Myocarditis in diseases classified elsewhere
0.023 0.977 0.000
I40 Acute myocarditis
0.023 0.977 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.023 0.977 0.000
I32 Pericarditis in diseases classified elsewhere
0.023 0.977 0.000
H34 Retinal vascular occlusions
0.000 0.977 0.023
E13.8 With unspecified complications
0.000 0.977 0.023
E13.7 With multiple complications
0.000 0.977 0.023
E13.6 With other specified complications
0.000 0.977 0.023
E13.5 With peripheral circulatory complications
0.000 0.977 0.023
E13.4 With neurological complications
0.000 0.977 0.023
E13.3 With ophthalmic complications
0.000 0.977 0.023
E13.2 With renal complications
0.000 0.977 0.023
E13.1 With ketoacidosis
0.000 0.977 0.023
E13.0 With coma
0.000 0.977 0.023
H30-H36 Disorders of choroid and retina
0.000 0.977 0.023
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.023 0.977 0.000
H34.8 Other retinal vascular occlusions
0.000 0.978 0.022
E14.4 With neurological complications
0.000 0.978 0.022
E14.8 With unspecified complications
0.000 0.978 0.021
E14.7 With multiple complications
0.000 0.978 0.021
E14.6 With other specified complications
0.000 0.978 0.021
E14.2 Withrenal complications
0.000 0.978 0.021
E14.1 With ketoacidosis
0.000 0.978 0.021
E14.0 With coma
0.000 0.978 0.021
H33 Retinal detachments and breaks
0.000 0.979 0.021
H33.0 Retinal detachment with retinal break
0.000 0.979 0.021
E13.9 Without complications
0.000 0.979 0.021
I42.2 Other hypertrophic cardiomyopathy
0.021 0.979 0.000
E11.6 With other specified complications
0.000 0.979 0.020
E14.5 With peripheral circulatory complications
0.000 0.980 0.020
H34.2 Other retinal artery occlusions
0.000 0.980 0.020
I43.1 Cardiomyopathy in metabolic diseases
0.020 0.980 0.000
I30.8 Other forms of acute pericarditis
0.020 0.980 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.020 0.980 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.980 0.019
I36 Nonrheumatic tricuspid valve disorders
0.019 0.981 0.000
H31 Other disorders of choroid
0.000 0.981 0.019
I37 Pulmonary valve disorders
0.019 0.981 0.000
I30.1 Infective pericarditis
0.019 0.981 0.000
I33 Acute and subacute endocarditis
0.018 0.981 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.018 0.982 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.018 0.982 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.018 0.982 0.000
I45 Other conduction disorders
0.018 0.982 0.000
H33.1 Retinoschisis and retinal cysts
0.000 0.982 0.018
I45.4 Nonspecific intraventricular block
0.018 0.982 0.000
I51 Complications and ill-defined descriptions of heart disease
0.018 0.982 0.000
H33.3 Retinal breaks without detachment
0.000 0.983 0.017
I32.8 Pericarditis in other diseases classified elsewhere
0.017 0.983 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.017 0.983 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.017 0.983 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.017 0.983 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.017 0.983 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.017 0.983 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.017 0.983 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.017 0.983 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.017 0.983 0.000
I40.9 Acute myocarditis, unspecified
0.017 0.983 0.000
I40.8 Other acute myocarditis
0.017 0.983 0.000
I40.1 Isolated myocarditis
0.017 0.983 0.000
I40.0 Infective myocarditis
0.017 0.983 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.017 0.983 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.017 0.983 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.017 0.983 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.017 0.983 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.017 0.983 0.000
I48.4 Atypical atrial flutter
0.017 0.983 0.000
I48.3 Typical atrial flutter
0.017 0.983 0.000
I48.2 Chronic atrial fibrillation
0.017 0.983 0.000
I48.1 Persistent atrial fibrillation
0.017 0.983 0.000
I48.0 Paroxysmal atrial fibrillation
0.017 0.983 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.017 0.983 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.017 0.983 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.017 0.983 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.983 0.017
H34.0 Transient retinal artery occlusion
0.000 0.983 0.017
H34.1 Central retinal artery occlusion
0.000 0.983 0.017
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.983 0.017
M79.89 Other specified soft tissue disorders (Site unspecified)
0.017 0.983 0.000
I35.1 Aortic (valve) insufficiency
0.016 0.984 0.000
H31.8 Other specified disorders of choroid
0.000 0.984 0.016
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.016 0.984 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.984 0.016
I38 Endocarditis, valve unspecified
0.016 0.984 0.000
I45.6 Preexcitation syndrome
0.016 0.984 0.000
M79.8 Other specified soft tissue disorders
0.015 0.985 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.015 0.985 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.015 0.985 0.000
I46 Cardiac arrest
0.015 0.985 0.000
H30 Chorioretinal inflammation
0.000 0.985 0.014
M79.83 Other specified soft tissue disorders (Forearm)
0.015 0.985 0.000
H31.0 Chorioretinal scars
0.000 0.986 0.014
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.014 0.986 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.014 0.986 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.014 0.986 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.014 0.986 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.014 0.986 0.000
H31.9 Disorder of choroid, unspecified
0.000 0.986 0.014
H31.4 Choroidal detachment
0.000 0.986 0.014
H31.3 Choroidal haemorrhage and rupture
0.000 0.986 0.014
H31.2 Hereditary choroidal dystrophy
0.000 0.986 0.014
H31.1 Choroidal degeneration
0.000 0.986 0.014
I37.9 Pulmonary valve disorder, unspecified
0.014 0.986 0.000
I37.8 Other pulmonary valve disorders
0.014 0.986 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.014 0.986 0.000
I37.0 Pulmonary valve stenosis
0.014 0.986 0.000
I51.0 Cardiac septal defect, acquired
0.014 0.986 0.000
I45.9 Conduction disorder, unspecified
0.014 0.986 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.014 0.986 0.000
I33.9 Acute endocarditis, unspecified
0.013 0.986 0.000
I51.8 Other ill-defined heart diseases
0.014 0.986 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.014 0.986 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.013 0.987 0.000
R59.1 Generalised enlarged lymph nodes
0.013 0.987 0.000
S72.0 Fracture of neck of femur
0.001 0.987 0.012
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.013 0.987 0.000
I45.0 Right fascicular block
0.013 0.987 0.000
H33.4 Traction detachment of retina
0.000 0.987 0.013
I51.7 Cardiomegaly
0.013 0.987 0.000
H33.2 Serous retinal detachment
0.000 0.987 0.013
I51.5 Myocardial degeneration
0.013 0.987 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.013 0.987 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.013 0.987 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.988 0.012
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.988 0.012
I51.6 Cardiovascular disease, unspecified
0.012 0.988 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.012 0.988 0.000
H33.5 Other retinal detachments
0.000 0.988 0.012
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.012 0.988 0.000
M79.88 Other specified soft tissue disorders (Other)
0.012 0.988 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.011 0.989 0.000
I45.2 Bifascicular block
0.011 0.989 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.011 0.989 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.000 0.989 0.011
Y84.2 Radiological procedure and radiotherapy
0.000 0.989 0.011
I46.1 Sudden cardiac death, so described
0.011 0.989 0.000
H30.8 Other chorioretinal inflammations
0.000 0.989 0.010
H30.2 Posterior cyclitis
0.000 0.989 0.010
H30.1 Disseminated chorioretinal inflammation
0.000 0.989 0.010
H30.0 Focal chorioretinal inflammation
0.000 0.989 0.010
I45.8 Other specified conduction disorders
0.010 0.989 0.000
I31 Other diseases of pericardium
0.010 0.990 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.010 0.990 0.000
I45.3 Trifascicular block
0.010 0.990 0.000
S72.01 Fracture of neck of femur (open)
0.001 0.990 0.009
R22.9 Localised swelling, mass and lump, unspecified
0.010 0.990 0.000
I37.1 Pulmonary valve insufficiency
0.009 0.990 0.000
R59 Enlarged lymph nodes
0.010 0.990 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.009 0.990 0.000
I46.0 Cardiac arrest with successful resuscitation
0.009 0.991 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.009 0.991 0.000
I33.0 Acute and subacute infective endocarditis
0.009 0.991 0.000
I45.5 Other specified heart block
0.009 0.991 0.000
R59.9 Enlarged lymph nodes, unspecified
0.009 0.991 0.000
M79.2 Neuralgia and neuritis, unspecified
0.008 0.992 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.992 0.008
R59.0 Localised enlarged lymph nodes
0.008 0.992 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.008 0.992 0.000
D11.0 Parotid gland
0.000 0.992 0.008
I31.0 Chronic adhesive pericarditis
0.008 0.992 0.000
M15-M19 Arthrosis
0.008 0.992 0.000
I51.9 Heart disease, unspecified
0.008 0.992 0.000
I47 Paroxysmal tachycardia
0.008 0.992 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.008 0.992 0.000
I51.4 Myocarditis, unspecified
0.007 0.992 0.000
I31.8 Other specified diseases of pericardium
0.007 0.992 0.000
I31.2 Haemopericardium, not elsewhere classified
0.007 0.992 0.000
M79.1 Myalgia
0.008 0.992 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.008 0.992 0.000
I31.1 Chronic constrictive pericarditis
0.007 0.992 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.007 0.993 0.000
H35 Other retinal disorders
0.000 0.993 0.007
R49.0 Dysphonia
0.000 0.993 0.007
M79.19 Myalgia (Site unspecified)
0.007 0.993 0.000
C25.0 Head of pancreas
0.007 0.993 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.007 0.993 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.006 0.993 0.001
J92.9 Pleural plaque without asbestos
0.000 0.993 0.007
I34 Nonrheumatic mitral valve disorders
0.007 0.993 0.000
M79.16 Myalgia (Lower leg)
0.007 0.993 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.007 0.993 0.000
M15 Polyarthrosis
0.006 0.994 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.006 0.994 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.006 0.994 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.006 0.994 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.006 0.994 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.006 0.994 0.000
M79.9 Soft tissue disorder, unspecified
0.006 0.994 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.006 0.994 0.000
M79.3 Panniculitis, unspecified
0.006 0.994 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.000 0.994 0.006
H35.2 Other proliferative retinopathy
0.000 0.994 0.006
I47.0 Reentry ventricular arrhythmia
0.006 0.994 0.000
M79.69 Pain in limb (Site unspecified)
0.006 0.994 0.000
M54.12 Radiculopathy (Cervical region)
0.006 0.994 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.006 0.994 0.000
I49 Other cardiac arrhythmias
0.006 0.994 0.000
L05.9 Pilonidal cyst without abscess
0.000 0.994 0.006
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M54.19 Radiculopathy (Site unspecified)
0.006 0.994 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
H35.4 Peripheral retinal degeneration
0.000 0.994 0.006
M79.10 Myalgia (Multiple sites)
0.006 0.994 0.000
M79.17 Myalgia (Ankle and foot)
0.006 0.994 0.000
M79.14 Myalgia (Hand)
0.006 0.994 0.000
M79.13 Myalgia (Forearm)
0.006 0.994 0.000
M79.12 Myalgia (Upper arm)
0.006 0.994 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.006 0.994 0.000
M79.11 Myalgia (Shoulder region)
0.006 0.994 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.005 0.994 0.000
O97 Death from sequelae of direct obstetric causes
0.005 0.994 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.005 0.994 0.000
O95 Obstetric death of unspecified cause
0.005 0.994 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.005 0.994 0.000
H35.8 Other specified retinal disorders
0.000 0.994 0.006
H35.1 Retinopathy of prematurity
0.000 0.994 0.005
D37.7 Other digestive organs
0.005 0.995 0.000
I45.1 Other and unspecified right bundle-branch block
0.005 0.995 0.000
M54.1 Radiculopathy
0.005 0.995 0.000
I46.9 Cardiac arrest, unspecified
0.005 0.995 0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)
0.005 0.995 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.995 0.005
H35.9 Retinal disorder, unspecified
0.000 0.995 0.005
E14.9 Without complications
0.000 0.995 0.005
M10.97 Gout, unspecified (Ankle and foot)
0.005 0.995 0.000
M15.8 Other polyarthrosis
0.005 0.995 0.000
H35.7 Separation of retinal layers
0.000 0.995 0.005
I34.8 Other nonrheumatic mitral valve disorders
0.005 0.995 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.005 0.995 0.000
I49.5 Sick sinus syndrome
0.005 0.995 0.000
M79.5 Residual foreign body in soft tissue
0.005 0.995 0.000
M79.6 Pain in limb
0.005 0.995 0.000
I49.8 Other specified cardiac arrhythmias
0.005 0.995 0.000
R17 Unspecified jaundice
0.005 0.995 0.000
M15.9 Polyarthrosis, unspecified
0.005 0.995 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.005 0.995 0.000
M15.0 Primary generalised (osteo)arthrosis
0.005 0.995 0.000
M15.4 Erosive (osteo)arthrosis
0.005 0.995 0.000
M15.3 Secondary multiple arthrosis
0.005 0.995 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.005 0.995 0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec
0.005 0.995 0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)
0.005 0.995 0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)
0.005 0.995 0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)
0.005 0.995 0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)
0.005 0.995 0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)
0.005 0.995 0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)
0.005 0.995 0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)
0.005 0.995 0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)
0.005 0.995 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.005 0.995 0.000
M79.98 Soft tissue disorder, unspecified (Other)
0.005 0.995 0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M79.94 Soft tissue disorder, unspecified (Hand)
0.005 0.995 0.000
M79.93 Soft tissue disorder, unspecified (Forearm)
0.005 0.995 0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)
0.005 0.995 0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)
0.005 0.995 0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)
0.005 0.995 0.000
I49.1 Atrial premature depolarisation
0.005 0.995 0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
M79.39 Panniculitis, unspecified (Site unspecified)
0.005 0.995 0.000
M79.38 Panniculitis, unspecified (Other)
0.005 0.995 0.000
M79.37 Panniculitis, unspecified (Ankle and foot)
0.005 0.995 0.000
M79.36 Panniculitis, unspecified (Lower leg)
0.005 0.995 0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M79.34 Panniculitis, unspecified (Hand)
0.005 0.995 0.000
M79.33 Panniculitis, unspecified (Forearm)
0.005 0.995 0.000
M79.32 Panniculitis, unspecified (Upper arm)
0.005 0.995 0.000
M79.31 Panniculitis, unspecified (Shoulder region)
0.005 0.995 0.000
M79.30 Panniculitis, unspecified (Multiple sites)
0.005 0.995 0.000
M15.1 Heberden's nodes (with arthropathy)
0.005 0.995 0.000
M79.18 Myalgia (Other)
0.005 0.995 0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
M54.16 Radiculopathy (Lumbar region)
0.005 0.995 0.000
I49.2 Junctional premature depolarisation
0.004 0.995 0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium
0.004 0.995 0.000
H35.0 Background retinopathy and retinal vascular changes
0.000 0.995 0.004
I34.2 Nonrheumatic mitral (valve) stenosis
0.004 0.996 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.004 0.996 0.000
I44 Atrioventricular and left bundle-branch block
0.004 0.996 0.000
L05.0 Pilonidal cyst with abscess
0.000 0.996 0.004
M10.9 Gout, unspecified
0.004 0.996 0.000
O80.9 Single spontaneous delivery, unspecified
0.000 0.996 0.004
C25 Malignant neoplasm of pancreas
0.004 0.996 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.004 0.996 0.000
H35.5 Hereditary retinal dystrophy
0.000 0.996 0.004
L05 Pilonidal cyst
0.000 0.996 0.004
O96.9 Death from unspecified obstetric cause
0.004 0.996 0.000
O96.1 Death from indirect obstetric cause
0.004 0.996 0.000
O96.0 Death from direct obstetric cause
0.004 0.996 0.000
O97.9 Death from sequelae of obstetric cause, unspecified
0.004 0.996 0.000
O97.1 Death from sequelae of indirect obstetric cause
0.004 0.996 0.000
O97.0 Death from sequelae of direct obstetric cause
0.004 0.996 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.004 0.996 0.000
G61.8 Other inflammatory polyneuropathies
0.004 0.996 0.000
M79.64 Pain in limb (Hand)
0.004 0.996 0.000
G62 Other polyneuropathies
0.004 0.996 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.004 0.996 0.000
M54.14 Radiculopathy (Thoracic region)
0.004 0.996 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.004 0.996 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.004 0.996 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.004 0.996 0.000
M10 Gout
0.004 0.996 0.000
R49 Voice disturbances
0.000 0.996 0.004
F31.9 Bipolar affective disorder, unspecified
0.004 0.996 0.000
G62.0 Drug-induced polyneuropathy
0.004 0.996 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.004 0.996 0.000
I44.3 Other and unspecified atrioventricular block
0.004 0.996 0.000
C25.2 Tail of pancreas
0.004 0.996 0.000
G62.8 Other specified polyneuropathies
0.004 0.996 0.000
M70-M79 Other soft tissue disorders
0.004 0.996 0.000
I31.3 Pericardial effusion (noninflammatory)
0.004 0.996 0.000
M20.2 Hallux rigidus
0.000 0.996 0.004
M79.61 Pain in limb (Shoulder region)
0.004 0.996 0.000
M79.58 Residual foreign body in soft tissue (Other)
0.004 0.996 0.000
G61 Inflammatory polyneuropathy
0.004 0.996 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.000 0.996 0.004
M89.87 Other specified disorders of bone (Ankle and foot)
0.004 0.996 0.000
M10.94 Gout, unspecified (Hand)
0.004 0.996 0.000
R87.6 Abnormal cytological findings
0.004 0.996 0.000
C25.9 Pancreas, unspecified
0.004 0.996 0.000
I49.0 Ventricular fibrillation and flutter
0.004 0.996 0.000
M79.7 Fibromyalgia
0.004 0.996 0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)
0.004 0.996 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.004 0.996 0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)
0.004 0.996 0.000
M79.53 Residual foreign body in soft tissue (Forearm)
0.004 0.996 0.000
M79.52 Residual foreign body in soft tissue (Upper arm)
0.004 0.996 0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)
0.004 0.996 0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)
0.004 0.996 0.000
M79.68 Pain in limb (Other)
0.004 0.996 0.000
M79.63 Pain in limb (Forearm)
0.004 0.996 0.000
M17 Gonarthrosis [arthrosis of knee]
0.004 0.996 0.000
M15.99 Polyosteoarthritis, unspecified
0.004 0.996 0.000
M10.0 Idiopathic gout
0.004 0.996 0.000
M10.92 Gout, unspecified (Upper arm)
0.004 0.996 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.003 0.996 0.000
M71 Other bursopathies
0.004 0.996 0.000
M79.67 Pain in limb (Ankle and foot)
0.004 0.996 0.000
G62.9 Polyneuropathy, unspecified
0.004 0.996 0.000
M05-M14 Inflammatory polyarthropathies
0.004 0.996 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.004 0.996 0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)
0.003 0.996 0.000
G62.1 Alcoholic polyneuropathy
0.004 0.996 0.000
M20 Acquired deformities of fingers and toes
0.000 0.996 0.004
G61.9 Inflammatory polyneuropathy, unspecified
0.003 0.996 0.000
D11 Benign neoplasm of major salivary glands
0.000 0.996 0.004
C25.3 Pancreatic duct
0.003 0.996 0.000
H35.6 Retinal haemorrhage
0.000 0.996 0.003
M70 Soft tissue disorders related to use, overuse and pressure
0.004 0.996 0.000
R49.8 Other and unspecified voice disturbances
0.000 0.996 0.003
M17.4 Other secondary gonarthrosis, bilateral
0.003 0.996 0.000
M71.1 Other infective bursitis
0.003 0.996 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.004 0.996 0.000
S72 Fracture of femur
0.002 0.996 0.001
I44.4 Left anterior fascicular block
0.003 0.997 0.000
I44.5 Left posterior fascicular block
0.003 0.997 0.000
M10.98 Gout, unspecified (Other)
0.003 0.997 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
M10.91 Gout, unspecified (Shoulder region)
0.003 0.997 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.003 0.997 0.000
M71.12 Other infective bursitis (Upper arm)
0.003 0.997 0.000
C25.8 Overlapping lesion of pancreas
0.003 0.997 0.000
C25.7 Other parts of pancreas
0.003 0.997 0.000
C25.4 Endocrine pancreas
0.003 0.997 0.000
M17.3 Other posttraumatic gonarthrosis
0.003 0.997 0.000
M10.06 Idiopathic gout (Lower leg)
0.003 0.997 0.000
M10.93 Gout, unspecified (Forearm)
0.003 0.997 0.000
H35.3 Degeneration of macula and posterior pole
0.000 0.997 0.003
M14 Arthropathies in other diseases classified elsewhere
0.003 0.997 0.000
G62.2 Polyneuropathy due to other toxic agents
0.003 0.997 0.000
M10.4 Other secondary gout
0.003 0.997 0.000
M10.3 Gout due to impairment of renal function
0.003 0.997 0.000
M10.2 Drug-induced gout
0.003 0.997 0.000
M10.1 Lead-induced gout
0.003 0.997 0.000
M71.3 Other bursal cyst
0.003 0.997 0.000
Q21.1 Atrial septal defect
0.003 0.997 0.000
R49.2 Hypernasality and hyponasality
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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