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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6021270
log Bayes Factor = 2.35402
Chromosome 20   position 50,141,264  (GRCh37) Explore rs6021270 on Ensembl!
Variant rs6021270 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M45-M49 Spondylopathies
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
M65-M68 Disorders of synovium and tendon
0.987 0.013 0.000
M48 Other spondylopathies
0.977 0.023 0.000
M48.0 Spinal stenosis
0.970 0.030 0.000
M46 Other inflammatory spondylopathies
0.965 0.035 0.000
M40-M43 Deforming dorsopathies
0.964 0.036 0.000
M65 Synovitis and tenosynovitis
0.962 0.038 0.000
M47 Spondylosis
0.937 0.063 0.000
M50-M54 Other dorsopathies
0.937 0.063 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.931 0.069 0.000
M48.06 Spinal stenosis (Lumbar region)
0.924 0.076 0.000
M67 Other disorders of synovium and tendon
0.924 0.076 0.000
M54 Dorsalgia
0.917 0.083 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.896 0.104 0.000
M54.9 Dorsalgia, unspecified
0.881 0.119 0.000
M47.8 Other spondylosis
0.880 0.120 0.000
M41 Scoliosis
0.877 0.123 0.000
M43 Other deforming dorsopathies
0.867 0.133 0.000
M60-M63 Disorders of muscles
0.865 0.135 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.863 0.137 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.858 0.142 0.000
M67.8 Other specified disorders of synovium and tendon
0.844 0.156 0.000
M86-M90 Other osteopathies
0.841 0.159 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.828 0.172 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.823 0.177 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.820 0.180 0.000
M65.3 Trigger finger
0.815 0.184 0.000
Chapter VI Diseases of the nervous system
0.815 0.185 0.000
M54.5 Low back pain
0.812 0.188 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.806 0.194 0.000
M48.09 Spinal stenosis (Site unspecified)
0.803 0.197 0.000
M47.89 Other spondylosis (Site unspecified)
0.802 0.198 0.000
M41.9 Scoliosis, unspecified
0.801 0.199 0.000
G57 Mononeuropathies of lower limb
0.792 0.208 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.784 0.216 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.783 0.217 0.000
M66 Spontaneous rupture of synovium and tendon
0.781 0.219 0.000
M40 Kyphosis and lordosis
0.780 0.219 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.779 0.221 0.000
M47.2 Other spondylosis with radiculopathy
0.779 0.221 0.000
M54.8 Other dorsalgia
0.778 0.222 0.000
# Top node
0.776 0.224 0.000
Chapter I Certain infectious and parasitic diseases
0.775 0.225 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.773 0.226 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.767 0.233 0.000
M05-M14 Inflammatory polyarthropathies
0.766 0.234 0.000
G90-G99 Other disorders of the nervous system
0.766 0.234 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.763 0.237 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.762 0.238 0.000
M43.1 Spondylolisthesis
0.759 0.241 0.000
G30-G32 Other degenerative diseases of the nervous system
0.757 0.243 0.000
G57.6 Lesion of plantar nerve
0.754 0.246 0.000
M49 Spondylopathies in diseases classified elsewhere
0.753 0.247 0.000
M62 Other disorders of muscle
0.752 0.248 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.750 0.249 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.749 0.251 0.000
M65.8 Other synovitis and tenosynovitis
0.745 0.255 0.000
M47.1 Other spondylosis with myelopathy
0.744 0.255 0.000
Chapter II Neoplasms
0.743 0.257 0.000
M54.56 Low back pain (Lumbar region)
0.743 0.257 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.743 0.257 0.000
M65.1 Other infective (teno)synovitis
0.740 0.260 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.739 0.261 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.738 0.262 0.000
M51 Other intervertebral disk disorders
0.736 0.264 0.000
G57.8 Other mononeuropathies of lower limb
0.734 0.266 0.000
M46.4 Discitis, unspecified
0.727 0.273 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.724 0.276 0.000
M13 Other arthritis
0.724 0.276 0.000
M91-M94 Chondropathies
0.719 0.281 0.000
M54.3 Sciatica
0.718 0.282 0.000
Chapter XX External causes of morbidity and mortality
0.718 0.282 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.717 0.283 0.000
M48.02 Spinal stenosis (Cervical region)
0.714 0.286 0.000
B95-B98 Bacterial, viral and other infectious agents
0.712 0.288 0.000
W00-W19 Falls
0.712 0.288 0.000
M65.34 Trigger finger-Hand
0.711 0.289 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.711 0.289 0.000
M87 Osteonecrosis
0.711 0.289 0.000
C91 Lymphoid leukaemia
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.708 0.292 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.708 0.292 0.000
M43.0 Spondylolysis
0.708 0.292 0.000
M13.9 Arthritis, unspecified
0.701 0.299 0.000
M48.9 Spondylopathy, unspecified
0.701 0.299 0.000
M48.8 Other specified spondylopathies
0.701 0.299 0.000
M48.4 Fatigue fracture of vertebra
0.701 0.299 0.000
M48.3 Traumatic spondylopathy
0.701 0.299 0.000
M48.2 Kissing spine
0.701 0.299 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.701 0.299 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.696 0.304 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.695 0.305 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.695 0.305 0.000
M48.04 Spinal stenosis (Thoracic region)
0.695 0.305 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.695 0.305 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.695 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.692 0.308 0.000
M46.8 Other specified inflammatory spondylopathies
0.692 0.308 0.000
M46.5 Other infective spondylopathies
0.692 0.308 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.692 0.308 0.000
M46.2 Osteomyelitis of vertebra
0.692 0.308 0.000
M46.0 Spinal enthesopathy
0.692 0.308 0.000
M42 Spinal osteochondrosis
0.691 0.309 0.000
G30 Alzheimer's disease
0.691 0.309 0.000
M65.2 Calcific tendinitis
0.689 0.311 0.000
M65.0 Abscess of tendon sheath
0.689 0.311 0.000
M54.59 Low back pain (Site unspecified)
0.689 0.311 0.000
G91 Hydrocephalus
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
B35-B49 Mycoses
0.682 0.318 0.000
M53 Other dorsopathies, not elsewhere classified
0.681 0.319 0.000
M67.4 Ganglion
0.679 0.321 0.000
C92 Myeloid leukaemia
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.675 0.325 0.000
M41.8 Other forms of scoliosis
0.675 0.325 0.000
M47.84 Other spondylosis (Thoracic region)
0.675 0.325 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.674 0.326 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.672 0.328 0.000
M62.8 Other specified disorders of muscle
0.672 0.328 0.000
M89 Other disorders of bone
0.670 0.330 0.000
W19 Unspecified fall
0.670 0.330 0.000
B07 Viral warts
0.669 0.331 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.669 0.331 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.669 0.331 0.000
M54.2 Cervicalgia
0.668 0.332 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.667 0.332 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.667 0.332 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.667 0.332 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.667 0.332 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.667 0.332 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.667 0.332 0.000
M60 Myositis
0.665 0.335 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.664 0.336 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.663 0.337 0.000
M67.3 Transient synovitis
0.663 0.337 0.000
M67.0 Short Achilles tendon (acquired)
0.663 0.337 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.663 0.337 0.000
M67.1 Other contracture of tendon (sheath)
0.660 0.340 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.658 0.342 0.000
G58 Other mononeuropathies
0.657 0.342 0.000
M54.0 Panniculitis affecting regions of neck and back
0.657 0.343 0.000
C91.1 Chronic lymphocytic leukaemia
0.656 0.344 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.655 0.345 0.000
C83.3 Large cell (diffuse)
0.654 0.346 0.000
G40-G47 Episodic and paroxysmal disorders
0.653 0.347 0.000
G96 Other disorders of central nervous system
0.649 0.351 0.000
M40.2 Other and unspecified kyphosis
0.649 0.351 0.000
M45 Ankylosing spondylitis
0.646 0.354 0.000
G95 Other diseases of spinal cord
0.645 0.355 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.642 0.358 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.642 0.358 0.000
G30.9 Alzheimer's disease, unspecified
0.638 0.362 0.000
M54.6 Pain in thoracic spine
0.637 0.363 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.636 0.363 0.000
M54.86 Other dorsalgia (Lumbar region)
0.635 0.365 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
D22 Melanocytic naevi
0.633 0.367 0.000
D10-D36 Benign neoplasms
0.633 0.367 0.000
C92.1 Chronic myeloid leukaemia
0.632 0.368 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.632 0.368 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.632 0.368 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.632 0.368 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.632 0.368 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.632 0.368 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.631 0.369 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.631 0.369 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.631 0.369 0.000
G70-G73 Diseases of myoneural junction and muscle
0.630 0.370 0.000
M51.2 Other specified intervertebral disk displacement
0.630 0.370 0.000
M41.5 Other secondary scoliosis
0.629 0.371 0.000
M41.4 Neuromuscular scoliosis
0.629 0.371 0.000
M41.3 Thoracogenic scoliosis
0.629 0.371 0.000
M41.2 Other idiopathic scoliosis
0.629 0.371 0.000
M41.1 Juvenile idiopathic scoliosis
0.629 0.371 0.000
M41.0 Infantile idiopathic scoliosis
0.629 0.371 0.000
M54.4 Lumbago with sciatica
0.628 0.372 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.628 0.372 0.000
D22.5 Melanocytic naevi of trunk
0.626 0.374 0.000
M54.89 Other dorsalgia (Site unspecified)
0.624 0.375 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.624 0.376 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.624 0.376 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.624 0.376 0.000
C83.0 Small cell (diffuse)
0.624 0.376 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.624 0.376 0.000
Chapter XXII Codes for special purposes
0.623 0.377 0.000
M43.9 Deforming dorsopathy, unspecified
0.621 0.379 0.000
M43.8 Other specified deforming dorsopathies
0.621 0.379 0.000
M43.6 Torticollis
0.621 0.379 0.000
M43.5 Other recurrent vertebral subluxation
0.621 0.379 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.621 0.379 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.621 0.379 0.000
M43.2 Other fusion of spine
0.621 0.379 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.620 0.380 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.620 0.380 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.620 0.380 0.000
M61 Calcification and ossification of muscle
0.620 0.380 0.000
M90 Osteopathies in diseases classified elsewhere
0.618 0.382 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.616 0.384 0.000
M54.39 Sciatica (Site unspecified)
0.616 0.384 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.615 0.385 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.615 0.385 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.615 0.385 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.615 0.385 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.615 0.385 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.615 0.385 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.615 0.385 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.615 0.385 0.000
A30-A49 Other bacterial diseases
0.614 0.386 0.000
C93 Monocytic leukaemia
0.614 0.386 0.000
B50-B64 Protozoal diseases
0.613 0.387 0.000
M47.82 Other spondylosis (Cervical region)
0.611 0.389 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.609 0.391 0.000
M66.2 Spontaneous rupture of extensor tendons
0.609 0.391 0.000
W07 Fall involving chair
0.609 0.391 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.606 0.393 0.000
A80-A89 Viral infections of the central nervous system
0.606 0.394 0.000
W19.9 Unspecified place
0.605 0.395 0.000
C95 Leukaemia of unspecified cell type
0.605 0.395 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.603 0.397 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.602 0.398 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.600 0.400 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.600 0.400 0.000
M87.9 Osteonecrosis, unspecified
0.599 0.400 0.000
M86 Osteomyelitis
0.599 0.401 0.000
M51.4 Schmorl's nodes
0.599 0.401 0.000
M62.88 Other specified disorders of muscle (Other)
0.598 0.402 0.000
C91.0 Acute lymphoblastic leukaemia
0.598 0.402 0.000
M54.50 Low back pain (Multiple sites in spine)
0.596 0.404 0.000
A00-A09 Intestinal infectious diseases
0.594 0.406 0.000
G83 Other paralytic syndromes
0.594 0.406 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.593 0.407 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.592 0.408 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.592 0.408 0.000
M66.0 Rupture of popliteal cyst
0.592 0.408 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.592 0.408 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.590 0.409 0.000
M07 Psoriatic and enteropathic arthropathies
0.590 0.410 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.590 0.410 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.590 0.410 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.590 0.410 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.590 0.410 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.590 0.410 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.589 0.411 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.588 0.411 0.000
G81 Hemiplegia
0.587 0.413 0.000
M65.39 Trigger finger-Site unspec
0.585 0.415 0.000
M65.38 Trigger finger-Other
0.585 0.415 0.000
M65.37 Trigger finger-Ankle/foot
0.585 0.415 0.000
M65.36 Trigger finger-Lower leg
0.585 0.415 0.000
M65.35 Trigger finger-Pelvic/thigh
0.585 0.415 0.000
M65.33 Trigger finger-Forearm
0.585 0.415 0.000
M65.32 Trigger finger-Upper arm
0.585 0.415 0.000
M65.31 Trigger finger-Shldr region
0.585 0.415 0.000
M65.30 Trigger finger-Mult sites
0.585 0.415 0.000
M54.55 Low back pain (Thoracolumbar region)
0.582 0.418 0.000
M54.54 Low back pain-Thoracic
0.582 0.418 0.000
M54.53 Low back pain-Cervicothoracic
0.582 0.418 0.000
M54.52 Low back pain-Cervical
0.582 0.418 0.000
M54.51 Low back pain-Occipit-atl-axl
0.582 0.418 0.000
B37 Candidiasis
0.582 0.418 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.581 0.419 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.581 0.419 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.581 0.419 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.580 0.420 0.000
W08 Fall involving other furniture
0.579 0.421 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.578 0.422 0.000
G52 Disorders of other cranial nerves
0.578 0.422 0.000
D32 Benign neoplasm of meninges
0.577 0.423 0.000
G58.9 Mononeuropathy, unspecified
0.576 0.424 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.576 0.424 0.000
M43.06 Spondylolysis (Lumbar region)
0.576 0.424 0.000
M11 Other crystal arthropathies
0.576 0.424 0.000
G91.9 Hydrocephalus, unspecified
0.576 0.424 0.000
G93 Other disorders of brain
0.575 0.425 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.574 0.426 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.574 0.426 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.574 0.426 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.574 0.426 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.574 0.426 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.574 0.426 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.574 0.426 0.000
M80-M85 Disorders of bone density and structure
0.574 0.426 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.572 0.428 0.000
C45 Mesothelioma
0.572 0.428 0.000
W50-W64 Exposure to animate mechanical forces
0.571 0.429 0.000
B99-B99 Other infectious diseases
0.570 0.430 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.569 0.431 0.000
B44 Aspergillosis
0.569 0.431 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.568 0.431 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.568 0.432 0.000
G57.5 Tarsal tunnel syndrome
0.568 0.432 0.000
G57.4 Lesion of medial popliteal nerve
0.568 0.432 0.000
G57.3 Lesion of lateral popliteal nerve
0.568 0.432 0.000
G57.2 Lesion of femoral nerve
0.568 0.432 0.000
G57.0 Lesion of sciatic nerve
0.568 0.432 0.000
G95.9 Disease of spinal cord, unspecified
0.567 0.433 0.000
G43 Migraine
0.565 0.435 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.565 0.435 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.564 0.436 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.563 0.437 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.563 0.437 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.561 0.439 0.000
M47.86 Other spondylosis (Lumbar region)
0.561 0.439 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.561 0.439 0.000
W00 Fall on same level involving ice and snow
0.561 0.439 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.561 0.439 0.000
G44 Other headache syndromes
0.561 0.439 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.560 0.440 0.000
M66.4 Spontaneous rupture of other tendons
0.560 0.440 0.000
M66.3 Spontaneous rupture of flexor tendons
0.560 0.440 0.000
M66.1 Rupture of synovium
0.560 0.440 0.000
M40.5 Lordosis, unspecified
0.560 0.440 0.000
M40.4 Other lordosis
0.560 0.440 0.000
M40.3 Flatback syndrome
0.560 0.440 0.000
M40.1 Other secondary kyphosis
0.560 0.440 0.000
M40.0 Postural kyphosis
0.560 0.440 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.559 0.441 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.559 0.441 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.559 0.441 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.559 0.441 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.559 0.441 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.559 0.441 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.559 0.441 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.558 0.442 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.558 0.442 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.558 0.442 0.000
M54.84 Other dorsalgia (Thoracic region)
0.558 0.442 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.558 0.442 0.000
M54.82 Other dorsalgia (Cervical region)
0.558 0.442 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.558 0.442 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.558 0.442 0.000
G91.8 Other hydrocephalus
0.558 0.442 0.000
M51.8 Other specified intervertebral disk disorders
0.557 0.443 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.556 0.443 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.556 0.444 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.555 0.444 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.555 0.444 0.000
A75-A79 Rickettsioses
0.555 0.444 0.000
A70-A74 Other diseases caused by chlamydiae
0.555 0.444 0.000
A65-A69 Other spirochaetal diseases
0.555 0.444 0.000
A20-A28 Certain zoonotic bacterial diseases
0.555 0.444 0.000
A15-A19 Tuberculosis
0.555 0.444 0.000
W05 Fall involving wheelchair
0.555 0.445 0.000
M40.24 Other and unspecified kyphosis (Thoracic region)
0.555 0.445 0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.555 0.445 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.555 0.445 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.555 0.445 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.555 0.445 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.555 0.445 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.555 0.445 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.555 0.445 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.555 0.445 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.555 0.445 0.000
G51 Facial nerve disorders
0.554 0.446 0.000
G57.1 Meralgia paraesthetica
0.554 0.446 0.000
W13 Fall from, out of or through building or structure
0.553 0.447 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.553 0.447 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.553 0.447 0.000
M88 Paget's disease of bone [osteitis deformans]
0.551 0.448 0.000
A49 Bacterial infection of unspecified site
0.551 0.449 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.551 0.449 0.000
M12 Other specific arthropathies
0.549 0.450 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.549 0.450 0.000
M08 Juvenile arthritis
0.549 0.450 0.000
B19 Unspecified viral hepatitis
0.549 0.451 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.549 0.451 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.549 0.451 0.000
G92 Toxic encephalopathy
0.549 0.451 0.000
X60-X84 Intentional self-harm
0.549 0.451 0.000
M92 Other juvenile osteochondrosis
0.547 0.453 0.000
B16 Acute hepatitis B
0.547 0.453 0.000
M14 Arthropathies in other diseases classified elsewhere
0.546 0.453 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.546 0.454 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.544 0.456 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.544 0.456 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.544 0.456 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.544 0.456 0.000
M43.12 Spondylolisthesis (Cervical region)
0.544 0.456 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.544 0.456 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.544 0.456 0.000
G91.0 Communicating hydrocephalus
0.544 0.456 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.543 0.457 0.000
X50-X57 Overexertion, travel and privation
0.543 0.457 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.543 0.457 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.543 0.457 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.543 0.457 0.000
M87.2 Osteonecrosis due to previous trauma
0.541 0.458 0.000
G90 Disorders of autonomic nervous system
0.541 0.459 0.000
W17 Other fall from one level to another
0.540 0.460 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.540 0.460 0.000
M49.4 Neuropathic spondylopathy
0.540 0.460 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.540 0.460 0.000
M49.2 Enterobacterial spondylitis
0.540 0.460 0.000
M49.1 Brucella spondylitis
0.540 0.460 0.000
M49.0 Tuberculosis of spine
0.540 0.460 0.000
M62.9 Disorder of muscle, unspecified
0.539 0.460 0.000
M62.6 Muscle strain
0.539 0.460 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.539 0.460 0.000
M62.4 Contracture of muscle
0.539 0.460 0.000
M62.3 Immobility syndrome (paraplegic)
0.539 0.460 0.000
M62.2 Ischaemic infarction of muscle
0.539 0.460 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.539 0.460 0.000
M62.0 Diastasis of muscle
0.539 0.460 0.000
D22.9 Melanocytic naevi, unspecified
0.539 0.461 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.539 0.461 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.538 0.461 0.000
D34 Benign neoplasm of thyroid gland
0.538 0.462 0.000
B17 Other acute viral hepatitis
0.538 0.462 0.000
M94 Other disorders of cartilage
0.537 0.462 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.537 0.463 0.000
C94 Other leukaemias of specified cell type
0.537 0.463 0.000
C86 Other specified types of T/NK-cell lymphoma
0.537 0.463 0.000
Q80-Q89 Other congenital malformations
0.537 0.463 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.537 0.463 0.000
B37.8 Candidiasis of other sites
0.536 0.464 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.536 0.464 0.000
W02.9 Unspecified place
0.535 0.465 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.535 0.465 0.000
M43.02 Spondylolysis (Cervical region)
0.534 0.466 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.534 0.466 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.534 0.466 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.534 0.466 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.534 0.466 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.534 0.466 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.534 0.466 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.534 0.466 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.534 0.466 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.534 0.466 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.534 0.466 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.534 0.466 0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.534 0.466 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.534 0.466 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.534 0.466 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.534 0.466 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.534 0.466 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.534 0.466 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.534 0.466 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.534 0.466 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.534 0.466 0.000
C88 Malignant immunoproliferative diseases
0.533 0.466 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.533 0.467 0.000
C11 Malignant neoplasm of nasopharynx
0.533 0.467 0.000
M65.19 Other infective (teno)synovitis (Site unspecified)
0.530 0.470 0.000
M65.18 Other infective (teno)synovitis (Other)
0.530 0.470 0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.530 0.470 0.000
M65.16 Other infective (teno)synovitis (Lower leg)
0.530 0.470 0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.530 0.470 0.000
M65.13 Other infective (teno)synovitis (Forearm)
0.530 0.470 0.000
M65.12 Other infective (teno)synovitis (Upper arm)
0.530 0.470 0.000
M65.11 Other infective (teno)synovitis (Shoulder region)
0.530 0.470 0.000
M65.10 Other infective (teno)synovitis (Multiple sites)
0.530 0.470 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.530 0.470 0.000
C03 Malignant neoplasm of gum
0.530 0.470 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.529 0.470 0.000
W19.1 Residential institution
0.529 0.471 0.000
A04 Other bacterial intestinal infections
0.529 0.471 0.000
M89.5 Osteolysis
0.528 0.472 0.000
M51.3 Other specified intervertebral disk degeneration
0.528 0.472 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.528 0.472 0.000
W19.4 Street and highway
0.527 0.473 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.525 0.475 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.525 0.475 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.524 0.475 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.524 0.476 0.000
G53.0 Postzoster neuralgia
0.524 0.476 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.523 0.477 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.523 0.477 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.522 0.478 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.522 0.478 0.000
M60.0 Infective myositis
0.522 0.478 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.521 0.479 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.521 0.479 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.521 0.479 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.521 0.479 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.521 0.479 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.521 0.479 0.000
M46.42 Discitis, unspecified (Cervical region)
0.521 0.479 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.521 0.479 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.521 0.479 0.000
D48.7 Other specified sites
0.521 0.479 0.000
D36 Benign neoplasm of other and unspecified sites
0.520 0.480 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.520 0.480 0.000
M13.8 Other specified arthritis
0.519 0.481 0.000
M13.1 Monoarthritis, not elsewhere classified
0.519 0.481 0.000
W18 Other fall on same level
0.519 0.481 0.000
M54.22 Cervicalgia (Cervical region)
0.518 0.482 0.000
M89.0 Algoneurodystrophy
0.517 0.482 0.000
C93.1 Chronic monocytic leukaemia
0.517 0.483 0.000
W07.0 Home
0.517 0.483 0.000
W19.2 School, other institution and public administrative area
0.517 0.483 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.516 0.484 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.516 0.484 0.000
D32.9 Meninges, unspecified
0.515 0.484 0.000
G30.0 Alzheimer's disease with early onset
0.515 0.485 0.000
C10 Malignant neoplasm of oropharynx
0.515 0.485 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.515 0.485 0.000
M54.35 Sciatica (Thoracolumbar region)
0.515 0.485 0.000
M54.34 Sciatica-Thoracic
0.515 0.485 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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