TreeWAS – Variant ID: rs6025

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M79.66 Pain in limb (Lower leg)	1.000	0.000	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	1.000	0.000	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	1.000	0.000	0.000
D68.5 Primary Thrombophilia	1.000	0.000	0.000
D68.2 Hereditary deficiency of other clotting factors	1.000	0.000	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	1.000	0.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	1.000	0.000	0.000
D17 Benign lipomatous neoplasm	1.000	0.000	0.000
D68 Other coagulation defects	1.000	0.000	0.000
I80 Phlebitis and thrombophlebitis	1.000	0.000	0.000
M79 Other soft tissue disorders, not elsewhere classified	1.000	0.000	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	1.000	0.000	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	1.000	0.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M79.6 Pain in limb	1.000	0.000	0.000
M79.8 Other specified soft tissue disorders	1.000	0.000	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	1.000	0.000	0.000
Z86 Personal history of certain other diseases	1.000	0.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	1.000	0.000	0.000
J09-J18 Influenza and pneumonia	1.000	0.000	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.000	1.000
I26 Pulmonary embolism	1.000	0.000	0.000
Z92 Personal history of medical treatment	1.000	0.000	0.000
M70-M79 Other soft tissue disorders	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
J18 Pneumonia, organism unspecified	1.000	0.000	0.000
D10-D36 Benign neoplasms	0.999	0.001	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.999	0.001	0.000
D68.8 Other specified coagulation defects	0.999	0.001	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.999	0.001	0.000
R07 Pain in throat and chest	0.998	0.002	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.996	0.004	0.000
Chapter V Mental and behavioural disorders	0.993	0.007	0.000
R06 Abnormalities of breathing	0.992	0.008	0.000
J18.9 Pneumonia, unspecified	0.992	0.008	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.992	0.008	0.000
J90-J94 Other diseases of pleura	0.991	0.009	0.000
I60-I69 Cerebrovascular diseases	0.988	0.012	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.988	0.012	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.985	0.015	0.000
Chapter XX External causes of morbidity and mortality	0.985	0.015	0.000
R07.3 Other chest pain	0.985	0.015	0.000
I82 Other venous embolism and thrombosis	0.984	0.016	0.000
J18.1 Lobar pneumonia, unspecified	0.981	0.019	0.000
R06.0 Dyspnoea	0.979	0.021	0.000
J90 Pleural effusion, not elsewhere classified	0.978	0.022	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.977	0.023	0.000
Chapter VII Diseases of the eye and adnexa	0.976	0.024	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.976	0.024	0.000
G40-G47 Episodic and paroxysmal disorders	0.975	0.025	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.968	0.032	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.967	0.033	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.965	0.035	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.964	0.036	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.963	0.037	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.962	0.038	0.000
B95-B98 Bacterial, viral and other infectious agents	0.960	0.040	0.000
M05-M14 Inflammatory polyarthropathies	0.960	0.040	0.000
S50-S59 Injuries to the elbow and forearm	0.957	0.043	0.000
J84 Other interstitial pulmonary diseases	0.957	0.043	0.000
I82.8 Embolism and thrombosis of other specified veins	0.956	0.044	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.953	0.047	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.952	0.048	0.000
J95-J99 Other diseases of the respiratory system	0.951	0.049	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.951	0.049	0.000
Z89 Acquired absence of limb	0.949	0.051	0.000
M86-M90 Other osteopathies	0.946	0.054	0.000
I69 Sequelae of cerebrovascular disease	0.945	0.055	0.000
Z93 Artificial opening status	0.945	0.055	0.000
R42 Dizziness and giddiness	0.940	0.060	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.939	0.061	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.938	0.062	0.000
M79.69 Pain in limb (Site unspecified)	0.936	0.064	0.000
Chapter XIV Diseases of the genitourinary system	0.935	0.065	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.934	0.066	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.931	0.069	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.930	0.070	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.929	0.071	0.000
I84 Haemorrhoids	0.000	0.072	0.928
R91 Abnormal findings on diagnostic imaging of lung	0.928	0.072	0.000
Z88.6 Personal history of allergy to analgesic agent	0.928	0.072	0.000
I84.9 Unspecified haemorrhoids without complication	0.000	0.073	0.927
G40 Epilepsy	0.926	0.074	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.925	0.075	0.000
F03 Unspecified dementia	0.922	0.078	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.921	0.079	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.083	0.917
G80-G83 Cerebral palsy and other paralytic syndromes	0.916	0.084	0.000
Z91.5 Personal history of self-harm	0.916	0.084	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.916	0.084	0.000
S52 Fracture of forearm	0.913	0.087	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.912	0.088	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.911	0.089	0.000
J98 Other respiratory disorders	0.910	0.090	0.000
N20-N23 Urolithiasis	0.909	0.091	0.000
R05 Cough	0.908	0.092	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.904	0.096	0.000
B35-B49 Mycoses	0.903	0.097	0.000
G90-G99 Other disorders of the nervous system	0.901	0.099	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.901	0.099	0.000
R26 Abnormalities of gait and mobility	0.896	0.104	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.895	0.105	0.000
R06.5 Mouth breathing	0.894	0.106	0.000
Z71.8 Other specified counselling	0.894	0.106	0.000
H53-H54 Visual disturbances and blindness	0.894	0.106	0.000
R07.1 Chest pain on breathing	0.893	0.107	0.000
S70-S79 Injuries to the hip and thigh	0.892	0.108	0.000
M13 Other arthritis	0.892	0.108	0.000
J98.4 Other disorders of lung	0.892	0.108	0.000
N20 Calculus of kidney and ureter	0.890	0.110	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.890	0.110	0.000
F60-F69 Disorders of adult personality and behaviour	0.889	0.111	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.887	0.113	0.000
W00-W19 Falls	0.886	0.114	0.000
J14 Pneumonia due to Haemophilus influenzae	0.884	0.116	0.000
S52.6 Fracture of lower end of both ulna and radius	0.883	0.116	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.878	0.122	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.878	0.122	0.000
J40-J47 Chronic lower respiratory diseases	0.877	0.123	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.873	0.127	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.872	0.128	0.000
N20.0 Calculus of kidney	0.872	0.128	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.871	0.129	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.130	0.870
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.868	0.131	0.000
N10-N16 Renal tubulo-interstitial diseases	0.868	0.132	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.866	0.134	0.000
M65-M68 Disorders of synovium and tendon	0.865	0.135	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.864	0.136	0.000
R79 Other abnormal findings of blood chemistry	0.863	0.137	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.863	0.137	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.862	0.138	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.861	0.138	0.000
R09.1 Pleurisy	0.861	0.139	0.000
I60 Subarachnoid haemorrhage	0.860	0.139	0.000
J92 Pleural plaque	0.859	0.141	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.859	0.141	0.000
R27 Other lack of coordination	0.858	0.142	0.000
D80-D89 Certain disorders involving the immune mechanism	0.858	0.142	0.000
S20-S29 Injuries to the thorax	0.857	0.143	0.000
Z92.0 Personal history of contraception	0.857	0.143	0.000
D23 Other benign neoplasms of skin	0.857	0.143	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.856	0.144	0.000
N99-N99 Other disorders of the genitourinary system	0.855	0.145	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.855	0.145	0.000
D22 Melanocytic naevi	0.854	0.145	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.854	0.146	0.000
J18.0 Bronchopneumonia, unspecified	0.853	0.147	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.853	0.147	0.000
R07.0 Pain in throat	0.851	0.149	0.000
J81 Pulmonary oedema	0.849	0.151	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.846	0.154	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.845	0.155	0.000
D68.9 Coagulation defect, unspecified	0.844	0.155	0.000
S60-S69 Injuries to the wrist and hand	0.843	0.157	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.842	0.158	0.000
N13 Obstructive and reflux uropathy	0.840	0.160	0.000
I73 Other peripheral vascular diseases	0.840	0.160	0.000
M13.9 Arthritis, unspecified	0.840	0.160	0.000
R41.3 Other amnesia	0.839	0.161	0.000
Chapter XXII Codes for special purposes	0.839	0.161	0.000
J60-J70 Lung diseases due to external agents	0.839	0.161	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.836	0.164	0.000
G43 Migraine	0.836	0.164	0.000
B37 Candidiasis	0.836	0.164	0.000
G81 Hemiplegia	0.835	0.165	0.000
M50-M54 Other dorsopathies	0.835	0.165	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.834	0.166	0.000
I86 Varicose veins of other sites	0.833	0.167	0.000
C51-C58 Malignant neoplasms of female genital organs	0.833	0.167	0.000
M89 Other disorders of bone	0.832	0.168	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.831	0.169	0.000
D10 Benign neoplasm of mouth and pharynx	0.830	0.170	0.000
I74 Arterial embolism and thrombosis	0.830	0.170	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.828	0.172	0.000
I05-I09 Chronic rheumatic heart diseases	0.827	0.173	0.000
I27 Other pulmonary heart diseases	0.827	0.173	0.000
H53 Visual disturbances	0.825	0.175	0.000
T66-T78 Other and unspecified effects of external causes	0.825	0.175	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.824	0.176	0.000
R06.4 Hyperventilation	0.823	0.177	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.823	0.177	0.000
H18 Other disorders of cornea	0.822	0.178	0.000
Z89.5 Acquired absence of leg at or below knee	0.822	0.178	0.000
R07.4 Chest pain, unspecified	0.822	0.178	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.821	0.179	0.000
J44 Other chronic obstructive pulmonary disease	0.821	0.179	0.000
W20-W49 Exposure to inanimate mechanical forces	0.819	0.181	0.000
I72 Other aneurysm	0.819	0.181	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.819	0.181	0.000
G40.9 Epilepsy, unspecified	0.818	0.182	0.000
C32 Malignant neoplasm of larynx	0.817	0.183	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.816	0.184	0.000
D27 Benign neoplasm of ovary	0.816	0.184	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.816	0.184	0.000
F60 Specific personality disorders	0.814	0.186	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.814	0.186	0.000
C34 Malignant neoplasm of bronchus and lung	0.814	0.186	0.000
H50 Other strabismus	0.812	0.188	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.812	0.188	0.000
Z89.6 Acquired absence of leg above knee	0.811	0.189	0.000
M45-M49 Spondylopathies	0.809	0.191	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.808	0.192	0.000
D45 Polycythaemia vera	0.807	0.193	0.000
G93 Other disorders of brain	0.806	0.194	0.000
I30-I52 Other forms of heart disease	0.805	0.195	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.805	0.195	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.805	0.195	0.000
Z88.2 Personal history of allergy to sulphonamides	0.805	0.195	0.000
M71 Other bursopathies	0.804	0.196	0.000
Z93.8 Other artificial opening status	0.802	0.198	0.000
D16 Benign neoplasm of bone and articular cartilage	0.802	0.198	0.000
D31 Benign neoplasm of eye and adnexa	0.800	0.200	0.000
I85 Oesophageal varices	0.799	0.201	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.798	0.202	0.000
M79.9 Soft tissue disorder, unspecified	0.798	0.202	0.000
Z88.0 Personal history of allergy to penicillin	0.798	0.202	0.000
Z89.4 Acquired absence of foot and ankle	0.797	0.203	0.000
R09.0 Asphyxia	0.797	0.203	0.000
M67 Other disorders of synovium and tendon	0.795	0.205	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.794	0.206	0.000
B07 Viral warts	0.794	0.206	0.000
I62 Other nontraumatic intracranial haemorrhage	0.793	0.207	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.792	0.208	0.000
A15-A19 Tuberculosis	0.791	0.209	0.000
S72 Fracture of femur	0.790	0.210	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.790	0.210	0.000
V20-V29 Motorcycle rider injured in transport accident	0.789	0.211	0.000
S10-S19 Injuries to the neck	0.789	0.211	0.000
B25-B34 Other viral diseases	0.788	0.212	0.000
D23.7 Skin of lower limb, including hip	0.787	0.213	0.000
D69 Purpura and other haemorrhagic conditions	0.785	0.215	0.000
M05 Seropositive rheumatoid arthritis	0.785	0.215	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.785	0.215	0.000
D26 Other benign neoplasms of uterus	0.784	0.216	0.000
Z93.2 Ileostomy status	0.784	0.216	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.783	0.217	0.000
G30-G32 Other degenerative diseases of the nervous system	0.783	0.217	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.782	0.218	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.781	0.219	0.000
I84.5 External haemorrhoids without complication	0.000	0.220	0.780
I73.9 Peripheral vascular disease, unspecified	0.779	0.221	0.000
R41.0 Disorientation, unspecified	0.779	0.221	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.779	0.221	0.000
Z94 Transplanted organ and tissue status	0.778	0.221	0.000
A30-A49 Other bacterial diseases	0.777	0.223	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.777	0.223	0.000
G81.9 Hemiplegia, unspecified	0.776	0.224	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.776	0.224	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.776	0.224	0.000
I65.2 Occlusion and stenosis of carotid artery	0.776	0.224	0.000
N13.8 Other obstructive and reflux uropathy	0.775	0.225	0.000
R01 Cardiac murmurs and other cardiac sounds	0.774	0.226	0.000
I84.4 External haemorrhoids with other complications	0.000	0.226	0.774
J80 Adult respiratory distress syndrome	0.774	0.226	0.000
M91-M94 Chondropathies	0.774	0.226	0.000
I87 Other disorders of veins	0.774	0.226	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.773	0.227	0.000
G20-G26 Extrapyramidal and movement disorders	0.773	0.227	0.000
M79.5 Residual foreign body in soft tissue	0.772	0.228	0.000
V40-V49 Car occupant injured in transport accident	0.770	0.229	0.000
T86 Failure and rejection of transplanted organs and tissues	0.770	0.230	0.000
H53.8 Other visual disturbances	0.770	0.230	0.000
M86 Osteomyelitis	0.770	0.230	0.000
I71 Aortic aneurysm and dissection	0.770	0.230	0.000
W19 Unspecified fall	0.769	0.231	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.768	0.231	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.768	0.232	0.000
T85.2 Mechanical complication of intraocular lens	0.768	0.232	0.000
G40.8 Other epilepsy	0.768	0.232	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.768	0.232	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.767	0.233	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.767	0.233	0.000
D00-D09 In situ neoplasms	0.767	0.233	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.766	0.234	0.000
D32 Benign neoplasm of meninges	0.766	0.234	0.000
M13.94 Arthritis, unspecified (Hand)	0.766	0.234	0.000
M06 Other rheumatoid arthritis	0.765	0.235	0.000
Z93.5 Cystostomy status	0.765	0.235	0.000
I46 Cardiac arrest	0.765	0.235	0.000
M76 Enthesopathies of lower limb, excluding foot	0.764	0.236	0.000
M90 Osteopathies in diseases classified elsewhere	0.763	0.237	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.762	0.238	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.762	0.238	0.000
M13.98 Arthritis, unspecified (Other)	0.761	0.238	0.000
M89.8 Other specified disorders of bone	0.761	0.239	0.000
M88 Paget's disease of bone [osteitis deformans]	0.761	0.239	0.000
D86 Sarcoidosis	0.761	0.239	0.000
N00-N08 Glomerular diseases	0.760	0.240	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.240	0.760
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.759	0.241	0.000
I69.3 Sequelae of cerebral infarction	0.759	0.241	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.758	0.242	0.000
Z84 Family history of other conditions	0.757	0.243	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.757	0.243	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.756	0.244	0.000
M79.1 Myalgia	0.756	0.244	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.755	0.245	0.000
S52.7 Multiple fractures of forearm	0.753	0.246	0.000
T87 Complications peculiar to reattachment and amputation	0.753	0.247	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.753	0.247	0.000
M79.60 Pain in limb (Multiple sites)	0.753	0.247	0.000
R06.1 Stridor	0.753	0.247	0.000
J47 Bronchiectasis	0.752	0.248	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.751	0.249	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.751	0.249	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.750	0.250	0.000
Z74 Problems related to care-provider dependency	0.750	0.250	0.000
Z73 Problems related to life-management difficulty	0.750	0.250	0.000
I81 Portal vein thrombosis	0.749	0.251	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.748	0.252	0.000
J20-J22 Other acute lower respiratory infections	0.748	0.252	0.000
S50 Superficial injury of forearm	0.748	0.252	0.000
R94 Abnormal results of function studies	0.748	0.252	0.000
R07.2 Precordial pain	0.748	0.252	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.747	0.253	0.000
R27.0 Ataxia, unspecified	0.747	0.253	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.747	0.253	0.000
B37.0 Candidal stomatitis	0.746	0.254	0.000
X20-X29 Contact with venomous animals and plants	0.745	0.255	0.000
J91 Pleural effusion in conditions classified elsewhere	0.745	0.255	0.000
H18.5 Hereditary corneal dystrophies	0.744	0.256	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.744	0.256	0.000
S40-S49 Injuries to the shoulder and upper arm	0.742	0.258	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.742	0.258	0.000
A00-A09 Intestinal infectious diseases	0.742	0.258	0.000
C56 Malignant neoplasm of ovary	0.741	0.259	0.000
B02 Zoster [herpes zoster]	0.741	0.259	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.741	0.259	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.740	0.260	0.000
M79.64 Pain in limb (Hand)	0.740	0.260	0.000
A80-A89 Viral infections of the central nervous system	0.740	0.260	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.739	0.261	0.000
R26.0 Ataxic gait	0.739	0.261	0.000
X60-X84 Intentional self-harm	0.739	0.261	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.737	0.263	0.000
F01 Vascular dementia	0.737	0.263	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.736	0.264	0.000
G43.9 Migraine, unspecified	0.736	0.264	0.000
T79-T79 Certain early complications of trauma	0.736	0.264	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.736	0.264	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.735	0.265	0.000
M40-M43 Deforming dorsopathies	0.734	0.266	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.734	0.266	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.734	0.266	0.000
C34.1 Upper lobe, bronchus or lung	0.732	0.268	0.000
J92.9 Pleural plaque without asbestos	0.732	0.268	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.731	0.269	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.730	0.270	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.729	0.271	0.000
W19.9 Unspecified place	0.729	0.271	0.000
I67 Other cerebrovascular diseases	0.728	0.271	0.000
B37.8 Candidiasis of other sites	0.728	0.272	0.000
R73 Elevated blood glucose level	0.728	0.272	0.000
I86.4 Gastric varices	0.726	0.274	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.726	0.274	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.726	0.274	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.726	0.274	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.725	0.275	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.724	0.276	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.724	0.276	0.000
J69 Pneumonitis due to solids and liquids	0.723	0.277	0.000
G45.3 Amaurosis fugax	0.723	0.277	0.000
T93 Sequelae of injuries of lower limb	0.723	0.277	0.000
G44 Other headache syndromes	0.723	0.277	0.000
D23.5 Skin of trunk	0.722	0.278	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.721	0.279	0.000
Z93.3 Colostomy status	0.721	0.279	0.000
I05 Rheumatic mitral valve diseases	0.721	0.279	0.000
N25-N29 Other disorders of kidney and ureter	0.721	0.279	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.720	0.280	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.720	0.280	0.000
V80-V89 Other land transport accidents	0.720	0.280	0.000
H52 Disorders of refraction and accommodation	0.719	0.281	0.000
H55-H59 Other disorders of eye and adnexa	0.719	0.281	0.000
F99-F99 Unspecified mental disorder	0.718	0.281	0.000
B15-B19 Viral hepatitis	0.718	0.282	0.000
S20 Superficial injury of thorax	0.718	0.282	0.000
W22 Striking against or struck by other objects	0.717	0.283	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.717	0.283	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.717	0.283	0.000
D68.6 Other Thrombophilia	0.717	0.283	0.000
D68.4 Acquired coagulation factor deficiency	0.717	0.283	0.000
D68.1 Hereditary factor XI deficiency	0.717	0.283	0.000
D68.0 Von Willebrand's disease	0.717	0.283	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.717	0.283	0.000
M79.3 Panniculitis, unspecified	0.717	0.283	0.000
M79.2 Neuralgia and neuritis, unspecified	0.717	0.283	0.000
I88 Nonspecific lymphadenitis	0.717	0.283	0.000
Z81 Family history of mental and behavioural disorders	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M79.68 Pain in limb (Other)	0.717	0.283	0.000
M79.63 Pain in limb (Forearm)	0.717	0.283	0.000
M79.61 Pain in limb (Shoulder region)	0.717	0.283	0.000
M79.88 Other specified soft tissue disorders (Other)	0.717	0.283	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.717	0.283	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.717	0.283	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.717	0.283	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.717	0.283	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
I28 Other diseases of pulmonary vessels	0.717	0.283	0.000
J17 Pneumonia in diseases classified elsewhere	0.717	0.283	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.717	0.283	0.000
J12 Viral pneumonia, not elsewhere classified	0.717	0.283	0.000
J11 Influenza, virus not identified	0.717	0.283	0.000
J10 Influenza due to identified influenza virus	0.717	0.283	0.000
J09 Influenza due to certain identified influenza virus	0.717	0.283	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.717	0.283	0.000
Z92.9 Personal history of medical treatment, unspecified	0.717	0.283	0.000
Z92.8 Personal history of other medical treatment	0.717	0.283	0.000
Z92.5 Personal history of rehabilitation measures	0.717	0.283	0.000
G83 Other paralytic syndromes	0.717	0.283	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
D66 Hereditary factor VIII deficiency	0.717	0.283	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
D55-D59 Haemolytic anaemias	0.717	0.283	0.000
J18.8 Other pneumonia, organism unspecified	0.717	0.283	0.000
J18.2 Hypostatic pneumonia, unspecified	0.717	0.283	0.000
D30 Benign neoplasm of urinary organs	0.716	0.283	0.000
D29 Benign neoplasm of male genital organs	0.716	0.283	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.716	0.283	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.283	0.000
D19 Benign neoplasm of mesothelial tissue	0.716	0.283	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.716	0.283	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.716	0.283	0.000
R02 Gangrene, not elsewhere classified	0.716	0.283	0.000
M79.7 Fibromyalgia	0.716	0.284	0.000
S90-S99 Injuries to the ankle and foot	0.716	0.284	0.000
B99-B99 Other infectious diseases	0.716	0.284	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284	0.000
B65-B83 Helminthiases	0.716	0.284	0.000
B50-B64 Protozoal diseases	0.716	0.284	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284	0.000
A75-A79 Rickettsioses	0.716	0.284	0.000
A70-A74 Other diseases caused by chlamydiae	0.716	0.284	0.000
A65-A69 Other spirochaetal diseases	0.716	0.284	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.716	0.284	0.000
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284	0.000
S51 Open wound of forearm	0.716	0.284	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.716	0.284	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.716	0.284	0.000
Z93.1 Gastrostomy status	0.715	0.285	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.715	0.285	0.000
G80 Infantile cerebral palsy	0.715	0.285	0.000
I46.0 Cardiac arrest with successful resuscitation	0.712	0.288	0.000
J43 Emphysema	0.712	0.288	0.000
F60.9 Personality disorder, unspecified	0.712	0.288	0.000
R25 Abnormal involuntary movements	0.712	0.288	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.288	0.000
F70-F79 Mental retardation	0.712	0.288	0.000
R06.7 Sneezing	0.711	0.289	0.000
R06.6 Hiccough	0.711	0.289	0.000
R06.3 Periodic breathing	0.711	0.289	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.711	0.289	0.000
Z91.7 Personal history of female genital mutilation	0.711	0.289	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.711	0.289	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.711	0.289	0.000
Z91.2 Personal history of poor personal hygiene	0.711	0.289	0.000
M77 Other enthesopathies	0.710	0.290	0.000
M07 Psoriatic and enteropathic arthropathies	0.710	0.290	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.290	0.710
D34 Benign neoplasm of thyroid gland	0.710	0.290	0.000
J93 Pneumothorax	0.710	0.290	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.709	0.291	0.000
G70-G73 Diseases of myoneural junction and muscle	0.709	0.291	0.000
I42 Cardiomyopathy	0.709	0.291	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.708	0.292	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.708	0.292	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.708	0.292	0.000
R46 Symptoms and signs involving appearance and behaviour	0.708	0.292	0.000
R43 Disturbances of smell and taste	0.708	0.292	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.707	0.293	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.707	0.293	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.707	0.293	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.706	0.293	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.706	0.294	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations