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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6092354
log Bayes Factor = 1.46723
Chromosome 20   position 55,294,474  (GRCh37) Explore rs6092354 on Ensembl!
Variant rs6092354 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.035 0.965
I20-I25 Ischaemic heart diseases
0.000 0.038 0.962
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.039 0.961
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.044 0.956
I20 Angina pectoris
0.000 0.050 0.950
I20.0 Unstable angina
0.000 0.081 0.919
I21 Acute myocardial infarction
0.000 0.095 0.905
I20.9 Angina pectoris, unspecified
0.000 0.129 0.871
I21.9 Acute myocardial infarction, unspecified
0.000 0.130 0.870
I24 Other acute ischaemic heart diseases
0.000 0.166 0.834
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.275 0.724
I24.8 Other forms of acute ischaemic heart disease
0.000 0.279 0.721
I20.8 Other forms of angina pectoris
0.000 0.285 0.715
I25.1 Atherosclerotic heart disease
0.000 0.294 0.706
I25.6 Silent myocardial ischaemia
0.000 0.308 0.692
I25.5 Ischaemic cardiomyopathy
0.000 0.308 0.692
I25.4 Coronary artery aneurysm
0.000 0.308 0.692
I25.3 Aneurysm of heart
0.000 0.308 0.692
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.308 0.692
I23 Certain current complications following acute myocardial infarction
0.000 0.310 0.689
I20.1 Angina pectoris with documented spasm
0.000 0.319 0.681
I22 Subsequent myocardial infarction
0.000 0.339 0.661
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.351 0.649
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.351 0.649
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.351 0.649
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.358 0.642
I21.4 Acute subendocardial myocardial infarction
0.000 0.372 0.627
I24.1 Dressler's syndrome
0.000 0.402 0.598
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.402 0.598
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.483 0.517
I23.8 Other current complications following acute myocardial infarction
0.000 0.505 0.494
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.505 0.494
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.505 0.494
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.505 0.494
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.505 0.494
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.505 0.494
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.505 0.494
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.505 0.494
I22.8 Subsequent myocardial infarction of other sites
0.000 0.526 0.474
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.526 0.474
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.526 0.474
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.555 0.445
I25.2 Old myocardial infarction
0.000 0.639 0.361
Chapter IX Diseases of the circulatory system
0.000 0.645 0.355
I30-I52 Other forms of heart disease
0.000 0.686 0.314
I34 Nonrheumatic mitral valve disorders
0.000 0.711 0.289
I44 Atrioventricular and left bundle-branch block
0.000 0.720 0.280
I34.0 Mitral (valve) insufficiency
0.000 0.729 0.271
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.735 0.264
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.739 0.261
I42 Cardiomyopathy
0.000 0.745 0.255
I00-I02 Acute rheumatic fever
0.000 0.745 0.255
I45 Other conduction disorders
0.000 0.758 0.242
I10-I15 Hypertensive diseases
0.000 0.761 0.239
I60-I69 Cerebrovascular diseases
0.000 0.769 0.230
I35 Nonrheumatic aortic valve disorders
0.000 0.770 0.230
I05-I09 Chronic rheumatic heart diseases
0.000 0.771 0.229
I44.2 Atrioventricular block, complete
0.000 0.773 0.227
I44.7 Left bundle-branch block, unspecified
0.000 0.774 0.226
I52 Other heart disorders in diseases classified elsewhere
0.000 0.775 0.225
I48 Atrial fibrillation and flutter
0.000 0.775 0.225
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.775 0.225
I41 Myocarditis in diseases classified elsewhere
0.000 0.775 0.225
I40 Acute myocarditis
0.000 0.775 0.225
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.775 0.225
I37 Pulmonary valve disorders
0.000 0.775 0.225
I36 Nonrheumatic tricuspid valve disorders
0.000 0.775 0.225
I33 Acute and subacute endocarditis
0.000 0.775 0.225
I32 Pericarditis in diseases classified elsewhere
0.000 0.775 0.225
I30 Acute pericarditis
0.000 0.775 0.225
I46 Cardiac arrest
0.000 0.775 0.225
I38 Endocarditis, valve unspecified
0.000 0.776 0.224
I84 Haemorrhoids
0.000 0.781 0.219
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.782 0.218
I44.1 Atrioventricular block, second degree
0.000 0.785 0.215
I83 Varicose veins of lower extremities
0.000 0.785 0.215
I44.0 Atrioventricular block, first degree
0.000 0.788 0.212
I51 Complications and ill-defined descriptions of heart disease
0.000 0.790 0.210
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.791 0.209
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.793 0.207
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.793 0.207
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.793 0.207
I34.1 Mitral (valve) prolapse
0.000 0.793 0.207
I31 Other diseases of pericardium
0.000 0.797 0.203
I42.0 Dilated cardiomyopathy
0.000 0.798 0.202
I44.6 Other and unspecified fascicular block
0.000 0.799 0.201
I44.5 Left posterior fascicular block
0.000 0.799 0.201
I44.4 Left anterior fascicular block
0.000 0.799 0.201
I44.3 Other and unspecified atrioventricular block
0.000 0.799 0.201
I42.9 Cardiomyopathy, unspecified
0.000 0.803 0.197
I26 Pulmonary embolism
0.000 0.803 0.197
I49 Other cardiac arrhythmias
0.000 0.805 0.195
I27 Other pulmonary heart diseases
0.000 0.807 0.193
I28 Other diseases of pulmonary vessels
0.000 0.810 0.190
I45.1 Other and unspecified right bundle-branch block
0.000 0.810 0.190
I47 Paroxysmal tachycardia
0.000 0.812 0.188
I88 Nonspecific lymphadenitis
0.000 0.812 0.188
I87 Other disorders of veins
0.000 0.812 0.188
I81 Portal vein thrombosis
0.000 0.812 0.188
I46.0 Cardiac arrest with successful resuscitation
0.000 0.812 0.188
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.813 0.187
I85 Oesophageal varices
0.000 0.815 0.185
I42.8 Other cardiomyopathies
0.000 0.817 0.183
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.817 0.183
I42.6 Alcoholic cardiomyopathy
0.000 0.817 0.183
I42.5 Other restrictive cardiomyopathy
0.000 0.817 0.183
I42.4 Endocardial fibroelastosis
0.000 0.817 0.183
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.817 0.183
I42.2 Other hypertrophic cardiomyopathy
0.000 0.817 0.183
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.817 0.183
I02 Rheumatic chorea
0.000 0.817 0.183
I01 Rheumatic fever with heart involvement
0.000 0.817 0.183
I00 Rheumatic fever without mention of heart involvement
0.000 0.817 0.183
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.818 0.182
I84.8 Unspecified haemorrhoids with other complications
0.000 0.820 0.180
I80 Phlebitis and thrombophlebitis
0.000 0.821 0.179
I82 Other venous embolism and thrombosis
0.000 0.821 0.179
I69 Sequelae of cerebrovascular disease
0.000 0.822 0.178
I84.9 Unspecified haemorrhoids without complication
0.000 0.822 0.178
I35.1 Aortic (valve) insufficiency
0.000 0.825 0.175
I45.9 Conduction disorder, unspecified
0.000 0.826 0.173
I45.8 Other specified conduction disorders
0.000 0.826 0.173
I45.6 Preexcitation syndrome
0.000 0.826 0.173
I45.5 Other specified heart block
0.000 0.826 0.173
I45.4 Nonspecific intraventricular block
0.000 0.826 0.173
I45.3 Trifascicular block
0.000 0.826 0.173
I45.2 Bifascicular block
0.000 0.826 0.173
I45.0 Right fascicular block
0.000 0.826 0.173
I10 Essential (primary) hypertension
0.000 0.827 0.173
I15 Secondary hypertension
0.000 0.829 0.171
I13 Hypertensive heart and renal disease
0.000 0.829 0.171
I11 Hypertensive heart disease
0.000 0.829 0.171
I84.1 Internal haemorrhoids with other complications
0.000 0.829 0.171
I71 Aortic aneurysm and dissection
0.000 0.832 0.168
I60 Subarachnoid haemorrhage
0.000 0.833 0.167
I86 Varicose veins of other sites
0.000 0.834 0.166
I61 Intracerebral haemorrhage
0.000 0.834 0.166
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.835 0.165
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.835 0.165
I62 Other nontraumatic intracranial haemorrhage
0.000 0.835 0.165
I35.9 Aortic valve disorder, unspecified
0.000 0.835 0.165
I35.8 Other aortic valve disorders
0.000 0.835 0.165
I09 Other rheumatic heart diseases
0.000 0.835 0.165
I07 Rheumatic tricuspid valve diseases
0.000 0.835 0.165
I06 Rheumatic aortic valve diseases
0.000 0.835 0.165
I05 Rheumatic mitral valve diseases
0.000 0.835 0.165
I35.0 Aortic (valve) stenosis
0.000 0.836 0.163
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.838 0.162
I30.9 Acute pericarditis, unspecified
0.000 0.838 0.162
I30.8 Other forms of acute pericarditis
0.000 0.838 0.162
I30.1 Infective pericarditis
0.000 0.838 0.162
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.838 0.162
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.838 0.162
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.838 0.162
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.838 0.162
I33.9 Acute endocarditis, unspecified
0.000 0.838 0.162
I33.0 Acute and subacute infective endocarditis
0.000 0.838 0.162
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.838 0.162
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.838 0.162
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.838 0.162
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.838 0.162
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.838 0.162
I37.9 Pulmonary valve disorder, unspecified
0.000 0.838 0.162
I37.8 Other pulmonary valve disorders
0.000 0.838 0.162
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.838 0.162
I37.1 Pulmonary valve insufficiency
0.000 0.838 0.162
I37.0 Pulmonary valve stenosis
0.000 0.838 0.162
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.838 0.162
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.838 0.162
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.838 0.162
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.838 0.162
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.838 0.162
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.838 0.162
I40.9 Acute myocarditis, unspecified
0.000 0.838 0.162
I40.8 Other acute myocarditis
0.000 0.838 0.162
I40.1 Isolated myocarditis
0.000 0.838 0.162
I40.0 Infective myocarditis
0.000 0.838 0.162
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.838 0.162
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.838 0.162
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.838 0.162
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.838 0.162
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.838 0.162
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.838 0.162
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.838 0.162
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.838 0.162
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.838 0.162
I48.4 Atypical atrial flutter
0.000 0.838 0.162
I48.3 Typical atrial flutter
0.000 0.838 0.162
I48.2 Chronic atrial fibrillation
0.000 0.838 0.162
I48.1 Persistent atrial fibrillation
0.000 0.838 0.162
I48.0 Paroxysmal atrial fibrillation
0.000 0.838 0.162
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.838 0.162
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.838 0.162
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.838 0.162
I46.1 Sudden cardiac death, so described
0.000 0.839 0.161
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.840 0.160
I51.9 Heart disease, unspecified
0.000 0.841 0.159
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.843 0.157
I84.3 External thrombosed haemorrhoids
0.000 0.843 0.157
I84.0 Internal thrombosed haemorrhoids
0.000 0.843 0.157
I84.5 External haemorrhoids without complication
0.000 0.843 0.157
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.844 0.156
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.844 0.156
I99 Other and unspecified disorders of circulatory system
0.000 0.844 0.156
I31.9 Disease of pericardium, unspecified
0.000 0.845 0.155
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.846 0.154
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.846 0.154
I12 Hypertensive renal disease
0.000 0.846 0.154
I84.2 Internal haemorrhoids without complication
0.000 0.846 0.154
I73 Other peripheral vascular diseases
0.000 0.847 0.153
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.848 0.152
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.848 0.152
I51.6 Cardiovascular disease, unspecified
0.000 0.849 0.151
I51.5 Myocardial degeneration
0.000 0.849 0.151
I51.4 Myocarditis, unspecified
0.000 0.849 0.151
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.849 0.151
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.849 0.151
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.849 0.151
I51.0 Cardiac septal defect, acquired
0.000 0.849 0.151
I49.5 Sick sinus syndrome
0.000 0.849 0.150
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.850 0.150
I70 Atherosclerosis
0.000 0.850 0.150
I74 Arterial embolism and thrombosis
0.000 0.850 0.150
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.852 0.148
I47.1 Supraventricular tachycardia
0.000 0.852 0.148
I65.2 Occlusion and stenosis of carotid artery
0.000 0.853 0.147
I84.4 External haemorrhoids with other complications
0.000 0.854 0.146
I31.8 Other specified diseases of pericardium
0.000 0.854 0.145
I31.2 Haemopericardium, not elsewhere classified
0.000 0.854 0.145
I31.1 Chronic constrictive pericarditis
0.000 0.854 0.145
I31.0 Chronic adhesive pericarditis
0.000 0.854 0.145
I63 Cerebral infarction
0.000 0.854 0.145
I84.6 Residual haemorrhoidal skin tags
0.000 0.855 0.145
I49.8 Other specified cardiac arrhythmias
0.000 0.856 0.144
I49.0 Ventricular fibrillation and flutter
0.000 0.857 0.143
I27.2 Other secondary pulmonary hypertension
0.000 0.858 0.142
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.859 0.141
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.859 0.141
I51.8 Other ill-defined heart diseases
0.000 0.860 0.140
I49.4 Other and unspecified premature depolarisation
0.000 0.860 0.140
I49.2 Junctional premature depolarisation
0.000 0.860 0.140
I49.1 Atrial premature depolarisation
0.000 0.860 0.140
I08 Multiple valve diseases
0.000 0.861 0.139
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.861 0.139
I27.9 Pulmonary heart disease, unspecified
0.000 0.861 0.138
I27.8 Other specified pulmonary heart diseases
0.000 0.861 0.138
I27.1 Kyphoscoliotic heart disease
0.000 0.861 0.138
I27.0 Primary pulmonary hypertension
0.000 0.862 0.138
I51.7 Cardiomegaly
0.000 0.862 0.137
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.864 0.136
I28.8 Other specified diseases of pulmonary vessels
0.000 0.864 0.136
I28.1 Aneurysm of pulmonary artery
0.000 0.864 0.136
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.864 0.136
I50 Heart failure
0.000 0.864 0.135
I72 Other aneurysm
0.000 0.865 0.135
I47.0 Reentry ventricular arrhythmia
0.000 0.865 0.135
I87.9 Disorder of vein, unspecified
0.000 0.865 0.135
I87.8 Other specified disorders of veins
0.000 0.865 0.135
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.865 0.135
I87.1 Compression of vein
0.000 0.865 0.135
I87.0 Postphlebitic syndrome
0.000 0.865 0.135
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.865 0.135
I88.8 Other nonspecific lymphadenitis
0.000 0.865 0.135
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.865 0.135
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.865 0.135
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.867 0.133
I85.0 Oesophageal varices with bleeding
0.000 0.867 0.132
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.869 0.131
I01.8 Other acute rheumatic heart disease
0.000 0.869 0.131
I01.2 Acute rheumatic myocarditis
0.000 0.869 0.131
I01.1 Acute rheumatic endocarditis
0.000 0.869 0.131
I01.0 Acute rheumatic pericarditis
0.000 0.869 0.131
I02.9 Rheumatic chorea without heart involvement
0.000 0.869 0.131
I02.0 Rheumatic chorea with heart involvement
0.000 0.869 0.131
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.869 0.130
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.869 0.130
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.869 0.130
I65.1 Occlusion and stenosis of basilar artery
0.000 0.869 0.130
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.869 0.130
I85.9 Oesophageal varices without bleeding
0.000 0.870 0.129
I78 Diseases of capillaries
0.000 0.871 0.129
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.871 0.129
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.871 0.129
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.871 0.129
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.871 0.129
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.872 0.128
I82.3 Embolism and thrombosis of renal vein
0.000 0.872 0.128
I82.2 Embolism and thrombosis of vena cava
0.000 0.872 0.128
I82.1 Thrombophlebitis migrans
0.000 0.872 0.128
I82.0 Budd-Chiari syndrome
0.000 0.872 0.128
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.872 0.128
I69.3 Sequelae of cerebral infarction
0.000 0.872 0.128
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.872 0.128
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.872 0.128
I49.3 Ventricular premature depolarisation
0.000 0.874 0.126
I73.9 Peripheral vascular disease, unspecified
0.000 0.875 0.125
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.877 0.123
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.877 0.123
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.877 0.123
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.877 0.123
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.877 0.123
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.877 0.123
I15.9 Seconday hypertension, unspecified
0.000 0.877 0.123
I15.8 Other secondary hypertension
0.000 0.877 0.123
I15.2 Hypertension secondary to endocrine disorders
0.000 0.877 0.123
I15.1 Hypertension secondary to other renal disorders
0.000 0.877 0.123
I15.0 Renovascular hypertension
0.000 0.877 0.123
I67 Other cerebrovascular diseases
0.000 0.877 0.122
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.878 0.121
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.879 0.121
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.879 0.121
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.879 0.121
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.879 0.121
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.879 0.121
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.879 0.121
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.879 0.121
I71.0 Dissection of aorta [any part]
0.000 0.879 0.121
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.880 0.120
I60.8 Other subarachnoid haemorrhage
0.000 0.880 0.120
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.880 0.120
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.880 0.120
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.880 0.120
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.880 0.120
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.880 0.120
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.880 0.120
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.880 0.120
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.880 0.120
I95 Hypotension
0.000 0.880 0.119
I82.8 Embolism and thrombosis of other specified veins
0.000 0.880 0.119
I86.8 Varicose veins of other specified sites
0.000 0.880 0.119
I86.4 Gastric varices
0.000 0.880 0.119
I86.3 Vulval varices
0.000 0.880 0.119
I86.2 Pelvic varices
0.000 0.880 0.119
I86.0 Sublingual varices
0.000 0.880 0.119
I61.8 Other intracerebral haemorrhage
0.000 0.881 0.119
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.881 0.119
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.881 0.119
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.881 0.119
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.881 0.119
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.881 0.119
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.881 0.119
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.881 0.119
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.881 0.119
I62.1 Nontraumatic extradural haemorrhage
0.000 0.881 0.119
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.881 0.119
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.881 0.119
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.881 0.119
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.881 0.119
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.881 0.119
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.881 0.119
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.881 0.119
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.881 0.119
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.881 0.119
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.881 0.119
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
I68.0 Cerebral amyloid angiopathy
0.000 0.881 0.119
I05.9 Mitral valve disease, unspecified
0.000 0.882 0.118
I05.8 Other mitral valve diseases
0.000 0.882 0.118
I05.2 Mitral stenosis with insufficiency
0.000 0.882 0.118
I05.1 Rheumatic mitral insufficiency
0.000 0.882 0.118
I05.0 Mitral stenosis
0.000 0.882 0.118
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.882 0.118
I06.8 Other rheumatic aortic valve diseases
0.000 0.882 0.118
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.882 0.118
I06.1 Rheumatic aortic insufficiency
0.000 0.882 0.118
I06.0 Rheumatic aortic stenosis
0.000 0.882 0.118
I07.9 Tricuspid valve disease, unspecified
0.000 0.882 0.118
I07.8 Other tricuspid valve diseases
0.000 0.882 0.118
I07.2 Tricuspid stenosis with insufficiency
0.000 0.882 0.118
I07.1 Tricuspid insufficiency
0.000 0.882 0.118
I07.0 Tricuspid stenosis
0.000 0.882 0.118
I09.9 Rheumatic heart disease, unspecified
0.000 0.882 0.118
I09.8 Other specified rheumatic heart diseases
0.000 0.882 0.118
I09.2 Chronic rheumatic pericarditis
0.000 0.882 0.118
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.882 0.118
I09.0 Rheumatic myocarditis
0.000 0.882 0.118
I77 Other disorders of arteries and arterioles
0.000 0.883 0.117
I46.9 Cardiac arrest, unspecified
0.001 0.885 0.115
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.885 0.115
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.886 0.113
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.888 0.112
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.888 0.112
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.888 0.112
I97.1 Other functional disturbances following cardiac surgery
0.000 0.888 0.112
I97.0 Postcardiotomy syndrome
0.000 0.888 0.112
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.888 0.112
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.888 0.112
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.888 0.112
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.888 0.112
I98.0 Cardiovascular syphilis
0.000 0.888 0.112
I12.9 Hypertensive renal disease without renal failure
0.000 0.889 0.110
I73.8 Other specified peripheral vascular diseases
0.000 0.890 0.110
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.890 0.110
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.891 0.109
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.891 0.109
I89.1 Lymphangitis
0.000 0.891 0.109
I70.9 Generalised and unspecified atherosclerosis
0.000 0.892 0.108
I70.8 Atherosclerosis of other arteries
0.000 0.892 0.108
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.892 0.108
I70.1 Atherosclerosis of renal artery
0.000 0.892 0.108
I70.0 Atherosclerosis of aorta
0.000 0.892 0.108
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.892 0.108
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.892 0.108
I79.1 Aortitis in diseases classified elsewhere
0.000 0.892 0.108
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.892 0.108
I31.3 Pericardial effusion (noninflammatory)
0.000 0.892 0.107
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.892 0.107
I74.8 Embolism and thrombosis of other arteries
0.000 0.892 0.107
I74.5 Embolism and thrombosis of iliac artery
0.000 0.892 0.107
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.892 0.107
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.892 0.107
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.892 0.107
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.892 0.107
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.893 0.107
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.894 0.106
I63.8 Other cerebral infarction
0.000 0.895 0.104
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.895 0.104
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.895 0.104
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.895 0.104
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.895 0.104
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.895 0.104
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.895 0.104
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.899 0.101
I47.2 Ventricular tachycardia
0.000 0.899 0.101
I08.9 Multiple valve disease, unspecified
0.000 0.900 0.100
I08.8 Other multiple valve diseases
0.000 0.900 0.100
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.900 0.100
I49.9 Cardiac arrhythmia, unspecified
0.000 0.901 0.098
I86.1 Scrotal varices
0.000 0.902 0.098
I72.9 Aneurysm of unspecified site
0.000 0.903 0.097
I72.8 Aneurysm of other specified arteries
0.000 0.903 0.097
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.903 0.097
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.903 0.097
I72.3 Aneurysm of iliac artery
0.000 0.903 0.097
I72.2 Aneurysm of renal artery
0.000 0.903 0.097
I72.1 Aneurysm of artery of upper extremity
0.000 0.903 0.097
I72.0 Aneurysm of carotid artery
0.000 0.903 0.097
I50.9 Heart failure, unspecified
0.000 0.904 0.096
I08.0 Disorders of both mitral and aortic valves
0.000 0.904 0.095
I12.0 Hypertensive renal disease with renal failure
0.000 0.907 0.093
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.907 0.093
I78.9 Disease of capillaries, unspecified
0.000 0.907 0.092
I78.8 Other diseases of capillaries
0.000 0.907 0.092
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.907 0.092
I73.0 Raynaud's syndrome
0.000 0.909 0.091
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.909 0.090
I63.9 Cerebral infarction, unspecified
0.000 0.911 0.089
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.912 0.088
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.912 0.088
I67.5 Moyamoya disease
0.000 0.912 0.088
I67.4 Hypertensive encephalopathy
0.000 0.912 0.088
I67.3 Progressive vascular leukoencephalopathy
0.000 0.912 0.088
I67.2 Cerebral atherosclerosis
0.000 0.912 0.088
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.912 0.088
I95.8 Other hypotension
0.000 0.914 0.086
I95.0 Idiopathic hypotension
0.000 0.914 0.086
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.916 0.084
I77.8 Other specified disorders of arteries and arterioles
0.000 0.916 0.084
I77.5 Necrosis of artery
0.000 0.916 0.084
I77.4 Coeliac artery compression syndrome
0.000 0.916 0.084
I77.3 Arterial fibromuscular dysplasia
0.000 0.916 0.084
I77.2 Rupture of artery
0.000 0.916 0.084
I77.0 Arteriovenous fistula, acquired
0.000 0.916 0.084
I67.8 Other specified cerebrovascular diseases
0.000 0.917 0.083
I72.4 Aneurysm of artery of lower extremity
0.001 0.918 0.082
I95.1 Orthostatic hypotension
0.000 0.919 0.081
I67.9 Cerebrovascular disease, unspecified
0.000 0.920 0.080
I77.6 Arteritis, unspecified
0.000 0.921 0.079
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.922 0.077
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.922 0.077
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.922 0.077
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.922 0.077
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.922 0.077
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.922 0.077
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.922 0.077
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.922 0.077
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.922 0.077
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.922 0.077
I95.9 Hypotension, unspecified
0.000 0.926 0.074
I89.0 Lymphoedema, not elsewhere classified
0.001 0.926 0.073
I95.2 Hypotension due to drugs
0.000 0.926 0.074
I78.1 Naevus, nonneoplastic
0.001 0.928 0.071
I67.1 Cerebral aneurysm, nonruptured
0.000 0.932 0.068
I50.1 Left ventricular failure
0.000 0.934 0.066
I50.0 Congestive heart failure
0.000 0.934 0.066
I77.1 Stricture of artery
0.001 0.940 0.060
D12.8 Rectum
0.009 0.991 0.000
D12.0 Caecum
0.007 0.993 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.007 0.993 0.000
D12.4 Descending colon
0.007 0.993 0.000
D12.9 Anus and anal canal
0.006 0.994 0.000
D12.2 Ascending colon
0.006 0.994 0.000
D12.7 Rectosigmoid junction
0.006 0.994 0.000
D12.1 Appendix
0.005 0.995 0.000
D12.6 Colon, unspecified
0.005 0.995 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.000 0.997 0.003
D12.5 Sigmoid colon
0.003 0.997 0.000
D12.3 Transverse colon
0.003 0.997 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.002 0.998 0.000
S09.9 Unspecified injury of head
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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