TreeWAS – Variant ID: rs61849693

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
R50-R69 General symptoms and signs	0.997	0.003
Z00-Z13 Persons encountering health services for examination and investigation	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.995	0.005
H30-H36 Disorders of choroid and retina	0.991	0.009
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.990	0.010
Z03 Medical observation and evaluation for suspected diseases and conditions	0.986	0.014
Z12 Special screening examination for neoplasms	0.981	0.019
Z03.8 Observation for other suspected diseases and conditions	0.981	0.019
R63 Symptoms and signs concerning food and fluid intake	0.979	0.021
Chapter IX Diseases of the circulatory system	0.974	0.026
Chapter II Neoplasms	0.972	0.028
Z12.1 Special screening examination for neoplasm of intestinal tract	0.970	0.030
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.969	0.031
Chapter XX External causes of morbidity and mortality	0.961	0.039
Chapter V Mental and behavioural disorders	0.957	0.043
H35 Other retinal disorders	0.954	0.046
R55 Syncope and collapse	0.953	0.047
R63.4 Abnormal weight loss	0.953	0.047
O60-O75 Complications of labour and delivery	0.951	0.049
Chapter I Certain infectious and parasitic diseases	0.947	0.053
Chapter XIV Diseases of the genitourinary system	0.942	0.058
H53-H54 Visual disturbances and blindness	0.938	0.062
D70-D77 Other diseases of blood and blood-forming organs	0.936	0.064
Z96 Presence of other functional implants	0.935	0.065
Chapter IV Endocrine, nutritional and metabolic diseases	0.934	0.066
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.933	0.067
N80-N98 Noninflammatory disorders of female genital tract	0.931	0.069
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.928	0.072
S60-S69 Injuries to the wrist and hand	0.927	0.073
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.916	0.084
H33 Retinal detachments and breaks	0.915	0.085
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.915	0.085
Z88.0 Personal history of allergy to penicillin	0.906	0.094
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.905	0.095
R51 Headache	0.904	0.096
E10-E14 Diabetes mellitus	0.902	0.098
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.901	0.099
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.899	0.101
Chapter XI Diseases of the digestive system	0.898	0.102
D70 Agranulocytosis	0.897	0.103
O68 Labour and delivery complicated by foetal stress [distress]	0.896	0.104
N94.1 Dyspareunia	0.888	0.112
Z85 Personal history of malignant neoplasm	0.887	0.113
S50-S59 Injuries to the elbow and forearm	0.885	0.114
C50-C50 Malignant neoplasm of breast	0.885	0.115
O48 Prolonged pregnancy	0.884	0.116
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.883	0.117
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.882	0.118
E10 Insulin-dependent diabetes mellitus	0.882	0.118
B95-B98 Bacterial, viral and other infectious agents	0.881	0.119
Z87 Personal history of other diseases and conditions	0.879	0.121
Chapter XII Diseases of the skin and subcutaneous tissue	0.876	0.124
N87 Dysplasia of cervix uteri	0.875	0.125
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.873	0.127
R94 Abnormal results of function studies	0.870	0.130
C15-C26 Malignant neoplasms of digestive organs	0.870	0.130
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.869	0.131
K80 Cholelithiasis	0.868	0.132
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.865	0.135
S66 Injury of muscle and tendon at wrist and hand level	0.864	0.136
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.861	0.139
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.860	0.140
T36-T50 Poisoning by drugs, medicaments and biological substances	0.858	0.142
Z96.1 Presence of intraocular lens	0.857	0.143
I05-I09 Chronic rheumatic heart diseases	0.856	0.144
H53 Visual disturbances	0.853	0.147
R63.0 Anorexia	0.852	0.148
A30-A49 Other bacterial diseases	0.848	0.152
S00-S09 Injuries to the head	0.847	0.153
M05-M14 Inflammatory polyarthropathies	0.845	0.155
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.843	0.157
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.842	0.158
D60-D64 Aplastic and other anaemias	0.842	0.158
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.841	0.159
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.840	0.160
Z91 Personal history of risk-factors, not elsewhere classified	0.835	0.165
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.831	0.169
Z03.1 Observation for suspected malignant neoplasm	0.831	0.169
H00 Hordeolum and chalazion	0.830	0.170
H35.3 Degeneration of macula and posterior pole	0.830	0.170
I30-I52 Other forms of heart disease	0.830	0.170
O94-O99 Other obstetric conditions, not elsewhere classified	0.828	0.172
K80.2 Calculus of gallbladder without cholecystitis	0.826	0.174
K80.0 Calculus of gallbladder with acute cholecystitis	0.826	0.174
Z96.6 Presence of orthopaedic joint implants	0.825	0.175
Z87.1 Personal history of diseases of the digestive system	0.825	0.175
C50 Malignant neoplasm of breast	0.823	0.177
Z94 Transplanted organ and tissue status	0.822	0.178
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.821	0.179
D37-D48 Neoplasms of uncertain or unknown behaviour	0.820	0.180
H35.7 Separation of retinal layers	0.819	0.181
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.818	0.182
E10.9 Without complications	0.818	0.182
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.818	0.182
Z86 Personal history of certain other diseases	0.818	0.182
K70-K77 Diseases of liver	0.817	0.183
Z88.2 Personal history of allergy to sulphonamides	0.816	0.184
H55-H59 Other disorders of eye and adnexa	0.816	0.184
F30-F39 Mood [affective] disorders	0.816	0.184
H34 Retinal vascular occlusions	0.812	0.188
H35.8 Other specified retinal disorders	0.809	0.191
Z89 Acquired absence of limb	0.808	0.192
O80-O84 Delivery	0.807	0.193
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.806	0.194
Z85.3 Personal history of malignant neoplasm of breast	0.806	0.194
Z70-Z76 Persons encountering health services in other circumstances	0.805	0.195
H25-H28 Disorders of lens	0.804	0.196
H54 Blindness and low vision	0.802	0.198
N89 Other noninflammatory disorders of vagina	0.800	0.200
D50-D53 Nutritional anaemias	0.798	0.202
R94.5 Abnormal results of liver function studies	0.796	0.204
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.796	0.204
S20-S29 Injuries to the thorax	0.791	0.209
I60-I69 Cerebrovascular diseases	0.791	0.209
S00 Superficial injury of head	0.790	0.210
Z88.3 Personal history of allergy to other anti-infective agents	0.789	0.211
S90-S99 Injuries to the ankle and foot	0.789	0.211
Z81 Family history of mental and behavioural disorders	0.789	0.211
Z92 Personal history of medical treatment	0.788	0.212
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.787	0.213
C20 Malignant neoplasm of rectum	0.787	0.213
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.787	0.213
H33.0 Retinal detachment with retinal break	0.786	0.214
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.786	0.214
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.784	0.215
I80 Phlebitis and thrombophlebitis	0.783	0.217
M06 Other rheumatoid arthritis	0.783	0.217
C60-C63 Malignant neoplasms of male genital organs	0.782	0.218
C79 Secondary malignant neoplasm of other sites	0.782	0.218
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.782	0.218
Z93 Artificial opening status	0.781	0.219
K65-K67 Diseases of peritoneum	0.780	0.220
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.780	0.220
H10-H13 Disorders of conjunctiva	0.779	0.221
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.778	0.222
S52 Fracture of forearm	0.777	0.223
N87.9 Dysplasia of cervix uteri, unspecified	0.777	0.223
D69 Purpura and other haemorrhagic conditions	0.777	0.223
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.776	0.224
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.774	0.226
S68 Traumatic amputation of wrist and hand	0.774	0.226
O63 Long labour	0.773	0.227
C50.2 Upper-inner quadrant of breast	0.773	0.227
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.772	0.228
Z03.3 Observation for suspected nervous system disorder	0.771	0.229
H00.1 Chalazion	0.770	0.230
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.770	0.230
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.769	0.231
R57 Shock, not elsewhere classified	0.766	0.234
H53.2 Diplopia	0.765	0.235
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.764	0.236
F40-F48 Neurotic, stress-related and somatoform disorders	0.763	0.237
Z91.5 Personal history of self-harm	0.763	0.237
Y60-Y69 Misadventures to patients during surgical and medical care	0.762	0.238
R94.3 Abnormal results of cardiovascular function studies	0.761	0.239
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.759	0.241
H33.3 Retinal breaks without detachment	0.756	0.244
X60-X84 Intentional self-harm	0.756	0.244
E10.5 With peripheral circulatory complications	0.756	0.244
I27 Other pulmonary heart diseases	0.756	0.244
T66-T78 Other and unspecified effects of external causes	0.755	0.245
W20-W49 Exposure to inanimate mechanical forces	0.754	0.245
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.753	0.247
N87.0 Mild cervical dysplasia	0.752	0.248
F80-F89 Disorders of psychological development	0.752	0.248
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.750	0.250
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.750	0.250
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.750	0.250
R50 Fever of unknown origin	0.749	0.251
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.748	0.252
O32 Maternal care for known or suspected malpresentation of foetus	0.748	0.252
R60 Oedema, not elsewhere classified	0.747	0.253
D80-D89 Certain disorders involving the immune mechanism	0.746	0.254
R54 Senility	0.745	0.255
Chapter X Diseases of the respiratory system	0.745	0.255
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.744	0.256
Z95 Presence of cardiac and vascular implants and grafts	0.743	0.257
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.742	0.258
X40-X49 Accidental poisoning by and exposure to noxious substances	0.742	0.258
I07 Rheumatic tricuspid valve diseases	0.740	0.260
H33.2 Serous retinal detachment	0.739	0.261
D64 Other anaemias	0.739	0.261
I49 Other cardiac arrhythmias	0.738	0.262
L00-L08 Infections of the skin and subcutaneous tissue	0.736	0.264
N90 Other noninflammatory disorders of vulva and perineum	0.735	0.265
H35.4 Peripheral retinal degeneration	0.735	0.265
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.735	0.265
Z88.1 Personal history of allergy to other antibiotic agents	0.733	0.267
Chapter VI Diseases of the nervous system	0.733	0.267
E13 Other specified diabetes mellitus	0.732	0.268
M06.9 Rheumatoid arthritis, unspecified	0.732	0.268
N00-N08 Glomerular diseases	0.730	0.270
R26 Abnormalities of gait and mobility	0.730	0.270
R59 Enlarged lymph nodes	0.729	0.270
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.729	0.271
W00-W19 Falls	0.728	0.272
Z13 Special screening examination for other diseases and disorders	0.726	0.274
O66 Other obstructed labour	0.725	0.275
R61 Hyperhidrosis	0.725	0.275
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.722	0.278
S62 Fracture at wrist and hand level	0.721	0.279
I47 Paroxysmal tachycardia	0.721	0.279
N70-N77 Inflammatory diseases of female pelvic organs	0.720	0.279
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.720	0.280
M20-M25 Other joint disorders	0.720	0.280
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.720	0.280
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.720	0.280
E10.3 With ophthalmic complications	0.720	0.280
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.719	0.281
I70-I79 Diseases of arteries, arterioles and capillaries	0.719	0.281
F31 Bipolar affective disorder	0.719	0.281
N84 Polyp of female genital tract	0.718	0.282
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.718	0.282
S40-S49 Injuries to the shoulder and upper arm	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
A46 Erysipelas	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
H46-H48 Disorders of optic nerve and visual pathways	0.717	0.283
Chapter VIII Diseases of the ear and mastoid process	0.717	0.283
E70-E90 Metabolic disorders	0.717	0.283
Z84 Family history of other conditions	0.716	0.283
K81 Cholecystitis	0.716	0.284
R93 Abnormal findings on diagnostic imaging of other body structures	0.716	0.284
Z86.5 Personal history of other mental and behavioural disorders	0.716	0.284
M13 Other arthritis	0.715	0.284
T79-T79 Certain early complications of trauma	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
S10-S19 Injuries to the neck	0.715	0.285
N94.6 Dysmenorrhoea, unspecified	0.715	0.285
F99-F99 Unspecified mental disorder	0.715	0.285
R68 Other general symptoms and signs	0.715	0.285
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.715	0.285
R62 Lack of expected normal physiological development	0.715	0.285
R64 Cachexia	0.715	0.285
R58 Haemorrhage, not elsewhere classified	0.715	0.285
Z11 Special screening examination for infectious and parasitic diseases	0.714	0.286
Z10 Routine general health check-up of defined subpopulation	0.714	0.286
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.714	0.286
O85-O92 Complications predominantly related to the puerperium	0.713	0.287
O00-O08 Pregnancy with abortive outcome	0.712	0.288
R45 Symptoms and signs involving emotional state	0.710	0.289
H32 Chorioretinal disorders in diseases classified elsewhere	0.710	0.290
H31 Other disorders of choroid	0.710	0.290
H30 Chorioretinal inflammation	0.710	0.290
Chapter XXII Codes for special purposes	0.710	0.290
K66 Other disorders of peritoneum	0.710	0.290
D55-D59 Haemolytic anaemias	0.710	0.290
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.709	0.291
C64-C68 Malignant neoplasms of urinary tract	0.709	0.291
T88 Other complications of surgical and medical care, not elsewhere classified	0.709	0.291
O34 Maternal care for known or suspected abnormality of pelvic organs	0.709	0.291
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.709	0.291
Z03.6 Observation for suspected toxic effect from ingested substance	0.707	0.293
Z03.2 Observation for suspected mental and behavioural disorders	0.707	0.293
Z03.0 Observation for suspected tuberculosis	0.707	0.293
E10.4 With neurological complications	0.707	0.293
K86 Other diseases of pancreas	0.706	0.294
H53.4 Visual field defects	0.705	0.295
T84.0 Mechanical complication of internal joint prosthesis	0.704	0.296
Z88.6 Personal history of allergy to analgesic agent	0.704	0.296
Z12.9 Special screening examination for neoplasm, unspecified	0.703	0.297
Z12.8 Special screening examination for neoplasm of other sites	0.703	0.297
Z12.6 Special screening examination for neoplasm of bladder	0.703	0.297
Z12.5 Special screening examination for neoplasm of prostate	0.703	0.297
Z12.4 Special screening examination for neoplasm of cervix	0.703	0.297
Z12.3 Special screening examination for neoplasm of breast	0.703	0.297
Z12.2 Special screening examination for neoplasm of respiratory organs	0.703	0.297
Z12.0 Special screening examination for neoplasm of stomach	0.703	0.297
N60-N64 Disorders of breast	0.703	0.297
R63.8 Other symptoms and signs concerning food and fluid intake	0.702	0.298
R63.6 Insufficient intake of food and water due to self neglect	0.702	0.298
R63.5 Abnormal weight gain	0.702	0.298
R63.3 Feeding difficulties and mismanagement	0.702	0.298
R63.2 Polyphagia	0.702	0.298
R63.1 Polydipsia	0.702	0.298
H36 Retinal disorders in diseases classified elsewhere	0.702	0.298
S52.5 Fracture of lower end of radius	0.702	0.298
T15-T19 Effects of foreign body entering through natural orifice	0.702	0.298
T85 Complications of other internal prosthetic devices, implants and grafts	0.701	0.299
O72 Postpartum haemorrhage	0.701	0.299
E14 Unspecified diabetes mellitus	0.700	0.300
S51 Open wound of forearm	0.699	0.300
T84.2 Mechanical complication of internal fixation device of other bones	0.699	0.300
I00-I02 Acute rheumatic fever	0.698	0.301
D69.6 Thrombocytopenia, unspecified	0.698	0.302
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.697	0.303
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.697	0.303
C40-C41 Malignant neoplasms of bone and articular cartilage	0.697	0.303
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.697	0.303
A50-A64 Infections with a predominantly sexual mode of transmission	0.696	0.304
Z94.0 Kidney transplant status	0.696	0.304
Z04 Examination and observation for other reasons	0.696	0.304
J30-J39 Other diseases of upper respiratory tract	0.695	0.305
R17 Unspecified jaundice	0.695	0.305
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.695	0.305
Z03.5 Observation for other suspected cardiovascular diseases	0.695	0.305
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.695	0.305
Z88.7 Personal history of allergy to serum and vaccine	0.695	0.305
Z88.4 Personal history of allergy to anaesthetic agent	0.695	0.305
Z96.7 Presence of other bone and tendon implants	0.694	0.306
N99-N99 Other disorders of the genitourinary system	0.692	0.308
F17 Mental and behavioural disorders due to use of tobacco	0.691	0.308
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.691	0.309
H01 Other inflammation of eyelid	0.691	0.309
H35.0 Background retinopathy and retinal vascular changes	0.691	0.309
O20-O29 Other maternal disorders predominantly related to pregnancy	0.691	0.309
R56 Convulsions, not elsewhere classified	0.690	0.309
O69 Labour and delivery complicated by umbilical cord complications	0.690	0.310
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.689	0.311
Y35-Y36 Legal intervention and operations of war	0.689	0.311
Y10-Y34 Event of undetermined intent	0.689	0.311
Y00-Y09 Assault	0.689	0.311
X85-X99 Assault	0.689	0.311
X58-X59 Accidental exposure to other and unspecified factors	0.689	0.311
X50-X57 Overexertion, travel and privation	0.689	0.311
X30-X39 Exposure to forces of nature	0.689	0.311
X20-X29 Contact with venomous animals and plants	0.689	0.311
X10-X19 Contact with heat and hot substances	0.689	0.311
X00-X09 Exposure to smoke, fire and flames	0.689	0.311
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.689	0.311
W75-W84 Other accidental threats to breathing	0.689	0.311
W65-W74 Accidental drowning and submersion	0.689	0.311
W50-W64 Exposure to animate mechanical forces	0.689	0.311
V98-V99 Other and unspecified transport accidents	0.689	0.311
V95-V97 Air and space transport accidents	0.689	0.311
V90-V94 Water transport accidents	0.689	0.311
V80-V89 Other land transport accidents	0.689	0.311
V70-V79 Bus occupant injured in transport accident	0.689	0.311
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.689	0.311
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.689	0.311
V40-V49 Car occupant injured in transport accident	0.689	0.311
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.689	0.311
V20-V29 Motorcycle rider injured in transport accident	0.689	0.311
V01-V09 Pedestrian injured in transport accident	0.689	0.311
N25-N29 Other disorders of kidney and ureter	0.689	0.311
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.689	0.311
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.689	0.311
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.688	0.312
O42 Premature rupture of membranes	0.687	0.312
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313
B15-B19 Viral hepatitis	0.687	0.313
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.686	0.314
F70-F79 Mental retardation	0.686	0.314
F60-F69 Disorders of adult personality and behaviour	0.686	0.314
Z83 Family history of other specific disorders	0.685	0.315
R25 Abnormal involuntary movements	0.685	0.315
H55 Nystagmus and other irregular eye movements	0.684	0.316
H35.9 Retinal disorder, unspecified	0.684	0.316
H35.6 Retinal haemorrhage	0.684	0.316
H35.5 Hereditary retinal dystrophy	0.684	0.316
H35.2 Other proliferative retinopathy	0.684	0.316
H35.1 Retinopathy of prematurity	0.684	0.316
H34.8 Other retinal vascular occlusions	0.683	0.317
O75 Other complications of labour and delivery, not elsewhere classified	0.683	0.317
Y57 Other and unspecified drugs and medicaments	0.682	0.318
O74 Complications of anaesthesia during labour and delivery	0.682	0.318
O73 Retained placenta and membranes, without haemorrhage	0.682	0.318
O71 Other obstetric trauma	0.682	0.318
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.682	0.318
O65 Obstructed labour due to maternal pelvic abnormality	0.682	0.318
O64 Obstructed labour due to malposition and malpresentation of foetus	0.682	0.318
O62 Abnormalities of forces of labour	0.682	0.318
O61 Failed induction of labour	0.682	0.318
O60 Preterm delivery	0.682	0.318
N17-N19 Renal failure	0.682	0.318
H53.0 Amblyopia ex anopsia	0.682	0.318
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.681	0.319
I08 Multiple valve diseases	0.680	0.320
I50 Heart failure	0.680	0.320
H02 Other disorders of eyelid	0.679	0.321
B99-B99 Other infectious diseases	0.679	0.321
B90-B94 Sequelae of infectious and parasitic diseases	0.679	0.321
B85-B89 Pediculosis, acariasis and other infestations	0.679	0.321
B65-B83 Helminthiases	0.679	0.321
B50-B64 Protozoal diseases	0.679	0.321
B20-B24 Human immunodeficiency virus [HIV] disease	0.679	0.321
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.679	0.321
A80-A89 Viral infections of the central nervous system	0.679	0.321
A75-A79 Rickettsioses	0.679	0.321
A70-A74 Other diseases caused by chlamydiae	0.679	0.321
A65-A69 Other spirochaetal diseases	0.679	0.321
A20-A28 Certain zoonotic bacterial diseases	0.679	0.321
A15-A19 Tuberculosis	0.679	0.321
Z99.1 Dependence on respirator	0.679	0.321
R42 Dizziness and giddiness	0.678	0.322
I61 Intracerebral haemorrhage	0.678	0.322
H04 Disorders of lachrymal system	0.677	0.323
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.677	0.323
S00.8 Superficial injury of other parts of head	0.677	0.323
I38 Endocarditis, valve unspecified	0.677	0.323
D73 Diseases of spleen	0.674	0.326
C80 Malignant neoplasm without specification of site	0.674	0.326
H40-H42 Glaucoma	0.674	0.326
K80.4 Calculus of bile duct with cholecystitis	0.674	0.326
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.674	0.326
M45-M49 Spondylopathies	0.673	0.327
B97 Viral agents as the cause of diseases classified to other chapters	0.673	0.327
Z97 Presence of other devices	0.672	0.327
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.673	0.327
A49 Bacterial infection of unspecified site	0.672	0.328
C51-C58 Malignant neoplasms of female genital organs	0.672	0.328
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.672	0.328
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.672	0.328
I26 Pulmonary embolism	0.672	0.328
Z40-Z54 Persons encountering health services for specific procedures and health care	0.672	0.328
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.671	0.329
D75 Other diseases of blood and blood-forming organs	0.671	0.329
D74 Methaemoglobinaemia	0.671	0.329
D72 Other disorders of white blood cells	0.671	0.329
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.671	0.329
D71 Functional disorders of polymorphonuclear neutrophils	0.671	0.329
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.671	0.329
Z96.9 Presence of functional implant, unspecified	0.671	0.329
Z96.5 Presence of tooth-root and mandibular implants	0.671	0.329
Z96.4 Presence of endocrine implants	0.671	0.329
Z96.3 Presence of artificial larynx	0.671	0.329
Z96.2 Presence of otological and audiological implants	0.671	0.329
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.671	0.329
A41 Other septicaemia	0.671	0.329
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.670	0.329
Z89.5 Acquired absence of leg at or below knee	0.670	0.330
K70 Alcoholic liver disease	0.670	0.330
E40-E46 Malnutrition	0.670	0.330
E20-E35 Disorders of other endocrine glands	0.669	0.331
O45 Premature separation of placenta [abruptio placentae]	0.669	0.331
O44 Placenta praevia	0.669	0.331
O43 Placental disorders	0.669	0.331
O41 Other disorders of amniotic fluid and membranes	0.669	0.331
O35 Maternal care for known or suspected foetal abnormality and damage	0.669	0.331
O33 Maternal care for known or suspected disproportion	0.669	0.331
O31 Complications specific to multiple gestation	0.669	0.331
O40 Polyhydramnios	0.669	0.331
L50-L54 Urticaria and erythema	0.668	0.332
N87.1 Moderate cervical dysplasia	0.668	0.332
N98 Complications associated with artificial fertilisation	0.668	0.332
N91 Absent, scanty and rare menstruation	0.668	0.332
N82 Fistulae involving female genital tract	0.668	0.332
N96 Habitual aborter	0.668	0.332
D45 Polycythaemia vera	0.668	0.332
N97 Female infertility	0.667	0.333
Z99.2 Dependence on renal dialysis	0.667	0.333
N89.5 Stricture and atresia of vagina	0.667	0.333
Y40 Systemic antibiotics	0.666	0.333
R44 Other symptoms and signs involving general sensations and perceptions	0.666	0.334
D64.9 Anaemia, unspecified	0.666	0.334
Z95.5 Presence of coronary angioplasty implant and graft	0.666	0.334
O30 Multiple gestation	0.666	0.334
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.665	0.335
N94.5 Secondary dysmenorrhoea	0.665	0.335
N94.4 Primary dysmenorrhoea	0.665	0.335
N94.3 Premenstrual tension syndrome	0.665	0.335
N94.2 Vaginismus	0.665	0.335
N94.0 Mittelschmerz	0.665	0.335
I27.2 Other secondary pulmonary hypertension	0.665	0.335
R81 Glycosuria	0.664	0.335
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.665	0.335
S69 Other and unspecified injuries of wrist and hand	0.664	0.336
S67 Crushing injury of wrist and hand	0.664	0.336
S65 Injury of blood vessels at wrist and hand level	0.664	0.336
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.664	0.336
S60 Superficial injury of wrist and hand	0.664	0.336
Z29 Need for other prophylactic measures	0.664	0.336
Y86 Sequelae of other accidents	0.664	0.336
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.663	0.336
C15 Malignant neoplasm of oesophagus	0.663	0.337
F20 Schizophrenia	0.663	0.337
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.662	0.337
O82 Single delivery by Caesarean section	0.662	0.338
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.661	0.339
C50.3 Lower-inner quadrant of breast	0.661	0.339
I10-I15 Hypertensive diseases	0.661	0.339
Z92.2 Personal history of long-term (current) use of other medicaments	0.660	0.340
M80-M85 Disorders of bone density and structure	0.660	0.340
D50 Iron deficiency anaemia	0.660	0.340
F00-F09 Organic, including symptomatic, mental disorders	0.660	0.340
L20-L30 Dermatitis and eczema	0.660	0.340
T42.4 Benzodiazepines	0.660	0.340
C25 Malignant neoplasm of pancreas	0.659	0.341
K66.0 Peritoneal adhesions	0.659	0.341
H54.4 Blindness, one eye	0.659	0.341
S00.2 Other superficial injuries of eyelid and periocular area	0.659	0.341
I47.2 Ventricular tachycardia	0.659	0.341
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.658	0.342
L80-L99 Other disorders of the skin and subcutaneous tissue	0.658	0.342
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.657	0.343
R90 Abnormal findings on diagnostic imaging of central nervous system	0.657	0.343
R92 Abnormal findings on diagnostic imaging of breast	0.657	0.343
I07.1 Tricuspid insufficiency	0.657	0.343
O36 Maternal care for other known or suspected foetal problems	0.657	0.343

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations