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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61854878
log Bayes Factor = 14.7592
Chromosome 10   position 45,736,656  (GRCh37) Explore rs61854878 on Ensembl!
Variant rs61854878 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
S60-S69 Injuries to the wrist and hand
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
M19 Other arthrosis
0.989 0.011 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.988 0.012 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
M19.9 Arthrosis, unspecified
0.984 0.016 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
T81 Complications of procedures, not elsewhere classified
0.980 0.020 0.000
Chapter X Diseases of the respiratory system
0.974 0.026 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.971 0.029 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.967 0.033 0.000
B95-B98 Bacterial, viral and other infectious agents
0.961 0.039 0.000
J30-J39 Other diseases of upper respiratory tract
0.956 0.044 0.000
M17 Gonarthrosis [arthrosis of knee]
0.953 0.047 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.949 0.051 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.946 0.054 0.000
S00-S09 Injuries to the head
0.945 0.055 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.940 0.060 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.934 0.066 0.000
J40-J47 Chronic lower respiratory diseases
0.931 0.069 0.000
W00-W19 Falls
0.926 0.074 0.000
Z04 Examination and observation for other reasons
0.926 0.074 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.924 0.076 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.922 0.078 0.000
E20-E35 Disorders of other endocrine glands
0.920 0.080 0.000
S61 Open wound of wrist and hand
0.915 0.085 0.000
M19.94 Arthrosis, unspecified (Hand)
0.910 0.090 0.000
M70-M79 Other soft tissue disorders
0.910 0.090 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.902 0.098 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.901 0.099 0.000
Chapter II Neoplasms
0.901 0.099 0.000
Chapter XI Diseases of the digestive system
0.900 0.100 0.000
M19.98 Arthrosis, unspecified (Other)
0.900 0.100 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.896 0.104 0.000
Z93 Artificial opening status
0.896 0.104 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.895 0.105 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.895 0.105 0.000
M17.9 Gonarthrosis, unspecified
0.895 0.105 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.894 0.106 0.000
S20-S29 Injuries to the thorax
0.889 0.111 0.000
A30-A49 Other bacterial diseases
0.884 0.116 0.000
R47-R49 Symptoms and signs involving speech and voice
0.883 0.117 0.000
S64 Injury of nerves at wrist and hand level
0.882 0.118 0.000
E87.7 Fluid overload
0.881 0.119 0.000
J44 Other chronic obstructive pulmonary disease
0.878 0.122 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.878 0.122 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.878 0.122 0.000
Chapter VIII Diseases of the ear and mastoid process
0.876 0.124 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.876 0.124 0.000
E87.2 Acidosis
0.876 0.124 0.000
S80-S89 Injuries to the knee and lower leg
0.876 0.124 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.873 0.127 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.866 0.134 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.866 0.134 0.000
E86 Volume depletion
0.865 0.135 0.000
Z88.0 Personal history of allergy to penicillin
0.864 0.136 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.862 0.138 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.861 0.139 0.000
Z04.8 Examination and observation for other specified reasons
0.861 0.139 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.860 0.140 0.000
S70-S79 Injuries to the hip and thigh
0.859 0.141 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.858 0.142 0.000
S61.0 Open wound of finger(s) without damage to nail
0.857 0.143 0.000
V10-V19 Pedal cyclist injured in transport accident
0.855 0.145 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.854 0.146 0.000
T51 Toxic effect of alcohol
0.854 0.146 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.851 0.149 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.849 0.151 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.849 0.151 0.000
S01 Open wound of head
0.846 0.154 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.845 0.155 0.000
E83 Disorders of mineral metabolism
0.843 0.157 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.843 0.157 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.840 0.160 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.839 0.161 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.838 0.162 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.836 0.164 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.836 0.164 0.000
A00-A09 Intestinal infectious diseases
0.830 0.170 0.000
T40.2 Other opioids
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
E22 Hyperfunction of pituitary gland
0.826 0.174 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.825 0.175 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.825 0.175 0.000
S62 Fracture at wrist and hand level
0.825 0.175 0.000
S65 Injury of blood vessels at wrist and hand level
0.822 0.178 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.821 0.179 0.000
R42 Dizziness and giddiness
0.820 0.180 0.000
R79 Other abnormal findings of blood chemistry
0.819 0.181 0.000
M80-M85 Disorders of bone density and structure
0.818 0.182 0.000
Z97 Presence of other devices
0.818 0.182 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.818 0.182 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.817 0.183 0.000
S60 Superficial injury of wrist and hand
0.817 0.183 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.817 0.183 0.000
Z98 Other postsurgical states
0.815 0.185 0.000
Z93.3 Colostomy status
0.814 0.186 0.000
Z87 Personal history of other diseases and conditions
0.813 0.187 0.000
W19 Unspecified fall
0.811 0.189 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.809 0.191 0.000
A41 Other septicaemia
0.808 0.192 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.807 0.193 0.000
S50-S59 Injuries to the elbow and forearm
0.807 0.193 0.000
K05 Gingivitis and periodontal diseases
0.807 0.193 0.000
M50-M54 Other dorsopathies
0.806 0.194 0.000
M75 Shoulder lesions
0.806 0.194 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.804 0.196 0.000
J39 Other diseases of upper respiratory tract
0.804 0.196 0.000
Z94 Transplanted organ and tissue status
0.804 0.196 0.000
J32 Chronic sinusitis
0.802 0.198 0.000
E50-E64 Other nutritional deficiencies
0.801 0.199 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.800 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.799 0.201 0.000
C15-C26 Malignant neoplasms of digestive organs
0.796 0.204 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.796 0.204 0.000
K50-K52 Noninfective enteritis and colitis
0.795 0.205 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.790 0.210 0.000
R47 Speech disturbances, not elsewhere classified
0.787 0.213 0.000
J35 Chronic diseases of tonsils and adenoids
0.787 0.213 0.000
K13 Other diseases of lip and oral mucosa
0.786 0.214 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.786 0.214 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
X60-X84 Intentional self-harm
0.780 0.220 0.000
Chapter V Mental and behavioural disorders
0.778 0.222 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.778 0.222 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
M17.0 Primary gonarthrosis, bilateral
0.777 0.223 0.000
H90-H95 Other disorders of ear
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.776 0.224 0.000
T51.0 Ethanol
0.775 0.225 0.000
Z22 Carrier of infectious disease
0.773 0.227 0.000
Z91.6 Personal history of other physical trauma
0.773 0.227 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.773 0.227 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.772 0.228 0.000
Z04.3 Examination and observation following other accident
0.769 0.231 0.000
K52 Other non-infective gastro-enteritis and colitis
0.769 0.231 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.768 0.232 0.000
S09 Other and unspecified injuries of head
0.767 0.233 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.767 0.233 0.000
E16 Other disorders of pancreatic internal secretion
0.766 0.234 0.000
D60-D64 Aplastic and other anaemias
0.765 0.235 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.765 0.235 0.000
S64.4 Injury of digital nerve of other finger
0.762 0.238 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.761 0.238 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.761 0.239 0.000
J40 Bronchitis, not specified as acute or chronic
0.761 0.239 0.000
W20-W49 Exposure to inanimate mechanical forces
0.761 0.239 0.000
J38.3 Other diseases of vocal cords
0.761 0.239 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.761 0.239 0.000
Z91.5 Personal history of self-harm
0.760 0.240 0.000
M20-M25 Other joint disorders
0.759 0.241 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.758 0.242 0.000
W07 Fall involving chair
0.756 0.243 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.756 0.244 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.755 0.245 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.755 0.245 0.000
T43.2 Other and unspecified antidepressants
0.755 0.245 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.754 0.246 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.754 0.246 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.752 0.248 0.000
W13 Fall from, out of or through building or structure
0.751 0.249 0.000
B25-B34 Other viral diseases
0.749 0.251 0.000
K70-K77 Diseases of liver
0.749 0.251 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.748 0.252 0.000
J38.1 Polyp of vocal cord and larynx
0.748 0.252 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.748 0.252 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.747 0.253 0.000
E87.3 Alkalosis
0.747 0.253 0.000
S20 Superficial injury of thorax
0.746 0.254 0.000
R76 Other abnormal immunological findings in serum
0.745 0.254 0.000
M86-M90 Other osteopathies
0.745 0.255 0.000
S00 Superficial injury of head
0.744 0.256 0.000
T39.1 4-Aminophenol derivatives
0.744 0.256 0.000
E27 Other disorders of adrenal gland
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.742 0.258 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.742 0.258 0.000
M00-M03 Infectious arthropathies
0.742 0.258 0.000
M17.1 Other primary gonarthrosis
0.742 0.258 0.000
K35-K38 Diseases of appendix
0.741 0.259 0.000
Z93.2 Ileostomy status
0.741 0.259 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.740 0.260 0.000
J38.7 Other diseases of larynx
0.738 0.262 0.000
Chapter XXII Codes for special purposes
0.738 0.262 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.738 0.262 0.000
V20-V29 Motorcycle rider injured in transport accident
0.737 0.263 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.737 0.263 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.736 0.264 0.000
S72 Fracture of femur
0.736 0.264 0.000
J43 Emphysema
0.735 0.265 0.000
J42 Unspecified chronic bronchitis
0.734 0.266 0.000
Z93.1 Gastrostomy status
0.734 0.266 0.000
K14 Diseases of tongue
0.733 0.267 0.000
M75.5 Bursitis of shoulder
0.733 0.267 0.000
E88 Other metabolic disorders
0.732 0.268 0.000
J34 Other disorders of nose and nasal sinuses
0.731 0.269 0.000
Z02 Examination and encounter for administrative purposes
0.731 0.269 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.731 0.269 0.000
E87.6 Hypokalaemia
0.729 0.271 0.000
S69 Other and unspecified injuries of wrist and hand
0.729 0.271 0.000
S01.1 Open wound of eyelid and periocular area
0.729 0.271 0.000
Z87.8 Personal history of other specified conditions
0.728 0.272 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.728 0.272 0.000
R73 Elevated blood glucose level
0.727 0.273 0.000
S82 Fracture of lower leg, including ankle
0.726 0.274 0.000
A80-A89 Viral infections of the central nervous system
0.725 0.275 0.000
Z99.2 Dependence on renal dialysis
0.725 0.275 0.000
J38.0 Paralysis of vocal cords and larynx
0.724 0.276 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.724 0.276 0.000
R26 Abnormalities of gait and mobility
0.723 0.277 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.722 0.278 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.722 0.278 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.722 0.278 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.722 0.278 0.000
Z96 Presence of other functional implants
0.722 0.278 0.000
T39.0 Salicylates
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.722 0.278 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.722 0.278 0.000
B15-B19 Viral hepatitis
0.721 0.279 0.000
Y40 Systemic antibiotics
0.720 0.279 0.000
J20-J22 Other acute lower respiratory infections
0.720 0.280 0.000
B35-B49 Mycoses
0.719 0.281 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.718 0.282 0.000
C51-C58 Malignant neoplasms of female genital organs
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.717 0.283 0.000
C77.2 Intra-abdominal lymph nodes
0.716 0.284 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.715 0.285 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
S01.7 Multiple open wounds of head
0.714 0.286 0.000
K05.1 Chronic gingivitis
0.714 0.286 0.000
M15 Polyarthrosis
0.713 0.286 0.000
S67 Crushing injury of wrist and hand
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
M19.0 Primary arthrosis of other joints
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T86 Failure and rejection of transplanted organs and tissues
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
M19.8 Other specified arthrosis
0.709 0.291 0.000
M19.2 Other secondary arthrosis
0.709 0.291 0.000
M19.1 Posttraumatic arthrosis of other joints
0.709 0.291 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.708 0.292 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.708 0.292 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.708 0.292 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.708 0.292 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.708 0.292 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.708 0.292 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.708 0.292 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.708 0.292 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.708 0.292 0.000
T36 Poisoning by systemic antibiotics
0.708 0.292 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.708 0.292 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
Z00.0 General medical examination
0.707 0.293 0.000
T51.9 Alcohol, unspecified
0.707 0.293 0.000
S62.3 Fracture of other metacarpal bone
0.706 0.294 0.000
D64 Other anaemias
0.706 0.294 0.000
T63 Toxic effect of contact with venomous animals
0.705 0.294 0.000
S40-S49 Injuries to the shoulder and upper arm
0.705 0.294 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.705 0.295 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
S06 Intracranial injury
0.703 0.297 0.000
Z04.1 Examination and observation following transport accident
0.703 0.297 0.000
T81.9 Unspecified complication of procedure
0.703 0.297 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.703 0.297 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.703 0.297 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.703 0.297 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.703 0.297 0.000
R49 Voice disturbances
0.702 0.298 0.000
S81 Open wound of lower leg
0.702 0.298 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.701 0.299 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.701 0.299 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
Z29 Need for other prophylactic measures
0.699 0.301 0.000
S65.5 Injury of blood vessel(s) of other finger
0.699 0.301 0.000
E83.4 Disorders of magnesium metabolism
0.699 0.301 0.000
R40 Somnolence, stupor and coma
0.698 0.302 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.697 0.303 0.000
W19.9 Unspecified place
0.697 0.303 0.000
E16.2 Hypoglycaemia, unspecified
0.697 0.303 0.000
Z10 Routine general health check-up of defined subpopulation
0.696 0.303 0.000
S32 Fracture of lumbar spine and pelvis
0.695 0.305 0.000
J39.2 Other diseases of pharynx
0.695 0.305 0.000
E87.4 Mixed disorder of acid-base balance
0.694 0.306 0.000
E22.0 Acromegaly and pituitary gigantism
0.693 0.307 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.693 0.307 0.000
K08 Other disorders of teeth and supporting structures
0.692 0.308 0.000
S60.8 Other superficial injuries of wrist and hand
0.690 0.310 0.000
K12 Stomatitis and related lesions
0.690 0.310 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.690 0.310 0.000
Z22.3 Carrier of other specified bacterial diseases
0.689 0.311 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.689 0.311 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.688 0.312 0.000
J33 Nasal polyp
0.688 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.688 0.312 0.000
M72 Fibroblastic disorders
0.686 0.314 0.000
J37 Chronic laryngitis and laryngotracheitis
0.685 0.315 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.685 0.315 0.000
E83.5 Disorders of calcium metabolism
0.685 0.315 0.000
Chapter XIV Diseases of the genitourinary system
0.685 0.315 0.000
T42.4 Benzodiazepines
0.684 0.316 0.000
V18.0 Driver injured in nontraffic accident
0.684 0.316 0.000
M17.5 Other secondary gonarthrosis
0.684 0.316 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.684 0.316 0.000
M17.3 Other posttraumatic gonarthrosis
0.684 0.316 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.684 0.316 0.000
E53 Deficiency of other B group vitamins
0.683 0.317 0.000
J46 Status asthmaticus
0.683 0.317 0.000
K05.3 Chronic periodontitis
0.682 0.318 0.000
R74 Abnormal serum enzyme levels
0.680 0.319 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.680 0.320 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.679 0.321 0.000
Z89 Acquired absence of limb
0.678 0.322 0.000
Z84 Family history of other conditions
0.678 0.322 0.000
Z81 Family history of mental and behavioural disorders
0.678 0.322 0.000
S08 Traumatic amputation of part of head
0.677 0.323 0.000
S07 Crushing injury of head
0.677 0.323 0.000
S05 Injury of eye and orbit
0.677 0.323 0.000
S04 Injury of cranial nerves
0.677 0.323 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.677 0.323 0.000
H60-H62 Diseases of external ear
0.677 0.323 0.000
H93 Other disorders of ear, not elsewhere classified
0.677 0.323 0.000
A41.9 Septicaemia, unspecified
0.677 0.323 0.000
S01.8 Open wound of other parts of head
0.677 0.323 0.000
K90-K93 Other diseases of the digestive system
0.676 0.324 0.000
W06 Fall involving bed
0.676 0.324 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.675 0.325 0.000
Y83.4 Other reconstructive surgery
0.675 0.325 0.000
C77.9 Lymph node, unspecified
0.675 0.325 0.000
S80 Superficial injury of lower leg
0.674 0.325 0.000
J36 Peritonsillar abscess
0.674 0.326 0.000
R47.8 Other and unspecified speech disturbances
0.674 0.326 0.000
E29 Testicular dysfunction
0.674 0.326 0.000
W19.4 Street and highway
0.673 0.326 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.673 0.327 0.000
R87 Abnormal findings in specimens from female genital organs
0.671 0.329 0.000
Z04.9 Examination and observation for unspecified reason
0.671 0.329 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.671 0.329 0.000
M65 Synovitis and tenosynovitis
0.671 0.329 0.000
M25 Other joint disorders, not elsewhere classified
0.670 0.329 0.000
D45 Polycythaemia vera
0.670 0.330 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.669 0.331 0.000
R77 Other abnormalities of plasma proteins
0.669 0.331 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.669 0.331 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.669 0.331 0.000
R71 Abnormality of red blood cells
0.669 0.331 0.000
M77 Other enthesopathies
0.669 0.331 0.000
N17-N19 Renal failure
0.669 0.331 0.000
Z98.1 Arthrodesis status
0.669 0.331 0.000
S63.6 Sprain and strain of finger(s)
0.668 0.332 0.000
J41 Simple and mucopurulent chronic bronchitis
0.668 0.332 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.666 0.334 0.000
W18 Other fall on same level
0.664 0.336 0.000
W17 Other fall from one level to another
0.664 0.336 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.664 0.336 0.000
W15 Fall from cliff
0.664 0.336 0.000
W14 Fall from tree
0.664 0.336 0.000
W12 Fall on and from scaffolding
0.664 0.336 0.000
W11 Fall on and from ladder
0.664 0.336 0.000
W10 Fall on and from stairs and steps
0.664 0.336 0.000
W09 Fall involving playground equipment
0.664 0.336 0.000
W08 Fall involving other furniture
0.664 0.336 0.000
W05 Fall involving wheelchair
0.664 0.336 0.000
W04 Fall while being carried or supported by other persons
0.664 0.336 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.664 0.336 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.664 0.336 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.664 0.336 0.000
W00 Fall on same level involving ice and snow
0.664 0.336 0.000
M51 Other intervertebral disk disorders
0.664 0.336 0.000
M79.8 Other specified soft tissue disorders
0.664 0.336 0.000
Z04.6 General psychiatric examination, requested by authority
0.664 0.336 0.000
Z04.5 Examination and observation following other inflicted injury
0.664 0.336 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.664 0.336 0.000
Z04.2 Examination and observation following work accident
0.664 0.336 0.000
Z04.0 Blood-alcohol and blood-drug test
0.664 0.336 0.000
J32.4 Chronic pansinusitis
0.664 0.336 0.000
Z87.1 Personal history of diseases of the digestive system
0.664 0.336 0.000
K76 Other diseases of liver
0.664 0.336 0.000
D64.9 Anaemia, unspecified
0.663 0.337 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.662 0.338 0.000
E87.0 Hyperosmolality and hypernatraemia
0.662 0.338 0.000
T85.2 Mechanical complication of intraocular lens
0.662 0.338 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.662 0.338 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.662 0.338 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.662 0.338 0.000
T92 Sequelae of injuries of upper limb
0.662 0.338 0.000
T65 Toxic effect of other and unspecified substances
0.661 0.339 0.000
T62 Toxic effect of other noxious substances eaten as food
0.661 0.339 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.661 0.339 0.000
T60 Toxic effect of pesticides
0.661 0.339 0.000
T59 Toxic effect of other gases, fumes and vapours
0.661 0.339 0.000
T57 Toxic effect of other inorganic substances
0.661 0.339 0.000
T56 Toxic effect of metals
0.661 0.339 0.000
T54 Toxic effect of corrosive substances
0.661 0.339 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.661 0.339 0.000
T52 Toxic effect of organic solvents
0.661 0.339 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.661 0.339 0.000
T58 Toxic effect of carbon monoxide
0.661 0.339 0.000
T55 Toxic effect of soaps and detergents
0.661 0.339 0.000
S70 Superficial injury of hip and thigh
0.660 0.340 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.659 0.341 0.000
E34 Other endocrine disorders
0.659 0.341 0.000
E32 Diseases of thymus
0.659 0.341 0.000
E31 Polyglandular dysfunction
0.659 0.341 0.000
E30 Disorders of puberty, not elsewhere classified
0.659 0.341 0.000
E26 Hyperaldosteronism
0.659 0.341 0.000
E25 Adrenogenital disorders
0.659 0.341 0.000
E24 Cushing's syndrome
0.659 0.341 0.000
E20 Hypoparathyroidism
0.659 0.341 0.000
K02 Dental caries
0.659 0.341 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.659 0.341 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.656 0.343 0.000
S61.7 Multiple open wounds of wrist and hand
0.656 0.344 0.000
Z99.1 Dependence on respirator
0.656 0.344 0.000
N18 Chronic renal failure
0.656 0.344 0.000
S68 Traumatic amputation of wrist and hand
0.655 0.344 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.655 0.345 0.000
S01.3 Open wound of ear
0.655 0.345 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.655 0.345 0.000
M71 Other bursopathies
0.654 0.345 0.000
Z93.5 Cystostomy status
0.654 0.345 0.000
M76 Enthesopathies of lower limb, excluding foot
0.652 0.348 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.652 0.348 0.000
Z93.0 Tracheostomy status
0.652 0.348 0.000
Z94.0 Kidney transplant status
0.652 0.348 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.652 0.348 0.000
J60-J70 Lung diseases due to external agents
0.652 0.348 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.651 0.349 0.000
C77.1 Intrathoracic lymph nodes
0.651 0.349 0.000
Z94.8 Other transplanted organ and tissue status
0.650 0.350 0.000
M75.2 Bicipital tendinitis
0.650 0.350 0.000
M54 Dorsalgia
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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