TreeWAS – Variant ID: rs61864429

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.998	0.002	0.000
Chapter IX Diseases of the circulatory system	0.998	0.002	0.000
Chapter VIII Diseases of the ear and mastoid process	0.998	0.002	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003	0.000
C34 Malignant neoplasm of bronchus and lung	0.995	0.005	0.000
I73 Other peripheral vascular diseases	0.995	0.005	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.995	0.005	0.000
Chapter II Neoplasms	0.993	0.007	0.000
Chapter V Mental and behavioural disorders	0.993	0.007	0.000
Chapter XX External causes of morbidity and mortality	0.992	0.008	0.000
M20-M25 Other joint disorders	0.989	0.011	0.000
C34.9 Bronchus or lung, unspecified	0.989	0.011	0.000
H65-H75 Diseases of middle ear and mastoid	0.986	0.014	0.000
J90-J94 Other diseases of pleura	0.983	0.017	0.000
I73.9 Peripheral vascular disease, unspecified	0.982	0.018	0.000
W00-W19 Falls	0.981	0.019	0.000
H90-H95 Other disorders of ear	0.976	0.024	0.000
M25 Other joint disorders, not elsewhere classified	0.975	0.025	0.000
I60-I69 Cerebrovascular diseases	0.972	0.028	0.000
J40-J47 Chronic lower respiratory diseases	0.972	0.028	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.972	0.028	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.971	0.029	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.969	0.031	0.000
C34.1 Upper lobe, bronchus or lung	0.967	0.033	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.966	0.034	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.964	0.036	0.000
M20 Acquired deformities of fingers and toes	0.964	0.036	0.000
J20-J22 Other acute lower respiratory infections	0.963	0.037	0.000
J44 Other chronic obstructive pulmonary disease	0.963	0.037	0.000
W19 Unspecified fall	0.963	0.037	0.000
M25.7 Osteophyte	0.962	0.038	0.000
M80-M85 Disorders of bone density and structure	0.956	0.044	0.000
I61 Intracerebral haemorrhage	0.945	0.055	0.000
F60-F69 Disorders of adult personality and behaviour	0.944	0.056	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.940	0.060	0.000
Chapter VII Diseases of the eye and adnexa	0.937	0.063	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.937	0.063	0.000
I72 Other aneurysm	0.937	0.063	0.000
I73.0 Raynaud's syndrome	0.936	0.064	0.000
M20.4 Other hammer toe(s) (acquired)	0.934	0.066	0.000
H73 Other disorders of tympanic membrane	0.933	0.067	0.000
M25.78 Osteophyte (Other)	0.933	0.067	0.000
H91 Other hearing loss	0.932	0.068	0.000
W19.9 Unspecified place	0.928	0.072	0.000
I77 Other disorders of arteries and arterioles	0.926	0.074	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.925	0.075	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.923	0.077	0.000
J92 Pleural plaque	0.919	0.081	0.000
R50-R69 General symptoms and signs	0.915	0.085	0.000
I67 Other cerebrovascular diseases	0.913	0.087	0.000
J22 Unspecified acute lower respiratory infection	0.911	0.089	0.000
C34.3 Lower lobe, bronchus or lung	0.910	0.090	0.000
R69 Unknown and unspecified causes of morbidity	0.910	0.090	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.906	0.094	0.000
F30-F39 Mood [affective] disorders	0.901	0.099	0.000
H55-H59 Other disorders of eye and adnexa	0.897	0.103	0.000
F60 Specific personality disorders	0.897	0.103	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.897	0.103	0.000
H73.8 Other specified disorders of tympanic membrane	0.896	0.104	0.000
C15-C26 Malignant neoplasms of digestive organs	0.894	0.106	0.000
H53-H54 Visual disturbances and blindness	0.894	0.106	0.000
J43 Emphysema	0.892	0.108	0.000
H91.9 Hearing loss, unspecified	0.890	0.110	0.000
F41 Other anxiety disorders	0.889	0.111	0.000
H74 Other disorders of middle ear and mastoid	0.885	0.115	0.000
S50-S59 Injuries to the elbow and forearm	0.880	0.120	0.000
M40-M43 Deforming dorsopathies	0.875	0.124	0.000
J42 Unspecified chronic bronchitis	0.872	0.128	0.000
M80 Osteoporosis with pathological fracture	0.872	0.128	0.000
H10-H13 Disorders of conjunctiva	0.869	0.131	0.000
C18 Malignant neoplasm of colon	0.867	0.133	0.000
R59 Enlarged lymph nodes	0.864	0.136	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.861	0.139	0.000
H53 Visual disturbances	0.861	0.139	0.000
H65 Nonsuppurative otitis media	0.859	0.141	0.000
Chapter XXII Codes for special purposes	0.859	0.141	0.000
Chapter VI Diseases of the nervous system	0.859	0.141	0.000
J95-J99 Other diseases of the respiratory system	0.859	0.141	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.858	0.142	0.000
C32 Malignant neoplasm of larynx	0.854	0.146	0.000
F40 Phobic anxiety disorders	0.854	0.146	0.000
Q60-Q64 Congenital malformations of the urinary system	0.852	0.148	0.000
H90 Conductive and sensorineural hearing loss	0.849	0.151	0.000
I74 Arterial embolism and thrombosis	0.844	0.156	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.843	0.157	0.000
M25.76 Osteophyte (Lower leg)	0.842	0.158	0.000
F60.9 Personality disorder, unspecified	0.840	0.160	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.839	0.161	0.000
W08 Fall involving other furniture	0.838	0.161	0.000
J43.9 Emphysema, unspecified	0.836	0.164	0.000
M81 Osteoporosis without pathological fracture	0.834	0.166	0.000
J92.9 Pleural plaque without asbestos	0.833	0.167	0.000
J91 Pleural effusion in conditions classified elsewhere	0.833	0.167	0.000
F41.9 Anxiety disorder, unspecified	0.833	0.167	0.000
M86-M90 Other osteopathies	0.828	0.172	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.828	0.172	0.000
W19.2 School, other institution and public administrative area	0.825	0.175	0.000
H53.4 Visual field defects	0.824	0.176	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.824	0.176	0.000
I69 Sequelae of cerebrovascular disease	0.824	0.176	0.000
H93 Other disorders of ear, not elsewhere classified	0.823	0.177	0.000
J00-J06 Acute upper respiratory infections	0.821	0.179	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.821	0.179	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.820	0.180	0.000
H55 Nystagmus and other irregular eye movements	0.820	0.180	0.000
F45 Somatoform disorders	0.819	0.181	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.818	0.182	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.818	0.182	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.818	0.182	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.813	0.187	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.813	0.187	0.000
I67.2 Cerebral atherosclerosis	0.811	0.189	0.000
M41 Scoliosis	0.811	0.189	0.000
F33 Recurrent depressive disorder	0.808	0.192	0.000
M24 Other specific joint derangements	0.807	0.192	0.000
J94 Other pleural conditions	0.806	0.194	0.000
M20.1 Hallux valgus (acquired)	0.806	0.194	0.000
V20-V29 Motorcycle rider injured in transport accident	0.806	0.194	0.000
H11 Other disorders of conjunctiva	0.805	0.195	0.000
M25.71 Osteophyte (Shoulder region)	0.804	0.196	0.000
H71 Cholesteatoma of middle ear	0.803	0.197	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.800	0.200	0.000
R59.1 Generalised enlarged lymph nodes	0.798	0.202	0.000
J20 Acute bronchitis	0.797	0.203	0.000
V40-V49 Car occupant injured in transport accident	0.793	0.207	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.792	0.208	0.000
W19.4 Street and highway	0.792	0.208	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.790	0.210	0.000
I77.0 Arteriovenous fistula, acquired	0.789	0.211	0.000
J93 Pneumothorax	0.789	0.211	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.786	0.214	0.000
G81 Hemiplegia	0.786	0.214	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.785	0.215	0.000
C18.9 Colon, unspecified	0.784	0.216	0.000
I99 Other and unspecified disorders of circulatory system	0.784	0.216	0.000
G20-G26 Extrapyramidal and movement disorders	0.784	0.216	0.000
H53.2 Diplopia	0.782	0.218	0.000
I67.9 Cerebrovascular disease, unspecified	0.782	0.218	0.000
M91-M94 Chondropathies	0.782	0.218	0.000
H65.3 Chronic mucoid otitis media	0.780	0.220	0.000
W11 Fall on and from ladder	0.780	0.220	0.000
J92.0 Pleural plaque with presence of asbestos	0.780	0.220	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.780	0.220	0.000
M05-M14 Inflammatory polyarthropathies	0.779	0.221	0.000
D47.1 Chronic myeloproliferative disease	0.779	0.221	0.000
R54 Senility	0.774	0.226	0.000
I72.9 Aneurysm of unspecified site	0.774	0.226	0.000
C20 Malignant neoplasm of rectum	0.773	0.227	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.773	0.227	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.772	0.228	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.771	0.229	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.771	0.229	0.000
J03 Acute tonsillitis	0.770	0.230	0.000
S90-S99 Injuries to the ankle and foot	0.769	0.231	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.769	0.231	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.768	0.232	0.000
Q61 Cystic kidney disease	0.768	0.232	0.000
H57 Other disorders of eye and adnexa	0.767	0.233	0.000
Y00-Y09 Assault	0.766	0.233	0.000
S52 Fracture of forearm	0.765	0.235	0.000
M41.9 Scoliosis, unspecified	0.764	0.236	0.000
I78 Diseases of capillaries	0.764	0.236	0.000
G81.9 Hemiplegia, unspecified	0.764	0.236	0.000
V10-V19 Pedal cyclist injured in transport accident	0.763	0.237	0.000
J90 Pleural effusion, not elsewhere classified	0.761	0.239	0.000
I72.4 Aneurysm of artery of lower extremity	0.761	0.239	0.000
F43 Reaction to severe stress, and adjustment disorders	0.761	0.239	0.000
S51 Open wound of forearm	0.760	0.240	0.000
M25.5 Pain in joint	0.760	0.240	0.000
I72.8 Aneurysm of other specified arteries	0.759	0.241	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.759	0.241	0.000
M65-M68 Disorders of synovium and tendon	0.759	0.241	0.000
M21 Other acquired deformities of limbs	0.758	0.242	0.000
I72.0 Aneurysm of carotid artery	0.755	0.245	0.000
S40-S49 Injuries to the shoulder and upper arm	0.755	0.245	0.000
Y40 Systemic antibiotics	0.754	0.246	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.754	0.246	0.000
S20-S29 Injuries to the thorax	0.754	0.246	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.753	0.247	0.000
C18.5 Splenic flexure	0.753	0.247	0.000
S60-S69 Injuries to the wrist and hand	0.752	0.248	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.751	0.249	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.751	0.249	0.000
I62 Other nontraumatic intracranial haemorrhage	0.750	0.250	0.000
H11.3 Conjunctival haemorrhage	0.749	0.251	0.000
I77.8 Other specified disorders of arteries and arterioles	0.748	0.252	0.000
W50-W64 Exposure to animate mechanical forces	0.748	0.252	0.000
M89 Other disorders of bone	0.748	0.252	0.000
F60.3 Emotionally unstable personality disorder	0.748	0.252	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.747	0.253	0.000
F64 Gender identity disorders	0.744	0.256	0.000
D38.1 Trachea, bronchus and lung	0.744	0.256	0.000
F48 Other neurotic disorders	0.743	0.257	0.000
C18.2 Ascending colon	0.743	0.257	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.742	0.258	0.000
W13 Fall from, out of or through building or structure	0.742	0.258	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.741	0.259	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.741	0.259	0.000
J98 Other respiratory disorders	0.740	0.260	0.000
J21 Acute bronchiolitis	0.737	0.262	0.000
I67.8 Other specified cerebrovascular diseases	0.737	0.263	0.000
W08.0 Home	0.736	0.263	0.000
F40.2 Specific (isolated) phobias	0.736	0.264	0.000
C71 Malignant neoplasm of brain	0.735	0.265	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.734	0.266	0.000
M25.3 Other instability of joint	0.734	0.266	0.000
J03.9 Acute tonsillitis, unspecified	0.734	0.266	0.000
H90.2 Conductive hearing loss, unspecified	0.733	0.267	0.000
M00-M03 Infectious arthropathies	0.731	0.269	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.731	0.269	0.000
X60-X84 Intentional self-harm	0.731	0.269	0.000
M60-M63 Disorders of muscles	0.730	0.270	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.730	0.270	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.730	0.270	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.728	0.272	0.000
M25.0 Haemarthrosis	0.727	0.272	0.000
M25.9 Joint disorder, unspecified	0.726	0.274	0.000
H91.8 Other specified hearing loss	0.725	0.275	0.000
C34.2 Middle lobe, bronchus or lung	0.725	0.275	0.000
S80-S89 Injuries to the knee and lower leg	0.724	0.276	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.723	0.277	0.000
X20-X29 Contact with venomous animals and plants	0.722	0.278	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.720	0.280	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.720	0.280	0.000
I05-I09 Chronic rheumatic heart diseases	0.719	0.281	0.000
V80-V89 Other land transport accidents	0.717	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
H74.1 Adhesive middle ear disease	0.716	0.284	0.000
I00-I02 Acute rheumatic fever	0.716	0.284	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.716	0.284	0.000
H70 Mastoiditis and related conditions	0.715	0.285	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.715	0.285	0.000
H60-H62 Diseases of external ear	0.715	0.285	0.000
F41.1 Generalised anxiety disorder	0.714	0.286	0.000
C34.8 Overlapping lesion of bronchus and lung	0.713	0.286	0.000
I73.8 Other specified peripheral vascular diseases	0.713	0.287	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.713	0.287	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.713	0.287	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.713	0.287	0.000
C31 Malignant neoplasm of accessory sinuses	0.713	0.287	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.713	0.287	0.000
C37 Malignant neoplasm of thymus	0.713	0.287	0.000
C33 Malignant neoplasm of trachea	0.713	0.287	0.000
S10-S19 Injuries to the neck	0.713	0.287	0.000
H93.1 Tinnitus	0.712	0.288	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.712	0.288	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.288	0.000
F70-F79 Mental retardation	0.712	0.288	0.000
R63 Symptoms and signs concerning food and fluid intake	0.712	0.288	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.711	0.289	0.000
Y35-Y36 Legal intervention and operations of war	0.711	0.289	0.000
Y10-Y34 Event of undetermined intent	0.711	0.289	0.000
X85-X99 Assault	0.711	0.289	0.000
X50-X57 Overexertion, travel and privation	0.711	0.289	0.000
X30-X39 Exposure to forces of nature	0.711	0.289	0.000
X10-X19 Contact with heat and hot substances	0.711	0.289	0.000
X00-X09 Exposure to smoke, fire and flames	0.711	0.289	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.711	0.289	0.000
W75-W84 Other accidental threats to breathing	0.711	0.289	0.000
W65-W74 Accidental drowning and submersion	0.711	0.289	0.000
V98-V99 Other and unspecified transport accidents	0.711	0.289	0.000
V95-V97 Air and space transport accidents	0.711	0.289	0.000
V90-V94 Water transport accidents	0.711	0.289	0.000
V70-V79 Bus occupant injured in transport accident	0.711	0.289	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.711	0.289	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.711	0.289	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.711	0.289	0.000
V01-V09 Pedestrian injured in transport accident	0.711	0.289	0.000
F41.2 Mixed anxiety and depressive disorder	0.711	0.289	0.000
M84 Disorders of continuity of bone	0.711	0.289	0.000
F31 Bipolar affective disorder	0.711	0.289	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.710	0.289	0.001
W06 Fall involving bed	0.711	0.289	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.710	0.290	0.000
I77.6 Arteritis, unspecified	0.710	0.290	0.000
F45.8 Other somatoform disorders	0.709	0.290	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291	0.000
M33 Dermatopolymyositis	0.709	0.291	0.000
M32 Systemic lupus erythematosus	0.709	0.291	0.000
M30 Polyarteritis nodosa and related conditions	0.709	0.291	0.000
M82 Osteoporosis in diseases classified elsewhere	0.709	0.291	0.000
D45 Polycythaemia vera	0.708	0.292	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.707	0.293	0.000
H68 Eustachian salpingitis and obstruction	0.707	0.293	0.000
H67 Otitis media in diseases classified elsewhere	0.707	0.293	0.000
M85 Other disorders of bone density and structure	0.706	0.294	0.000
H74.0 Tympanosclerosis	0.705	0.295	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.704	0.296	0.000
C32.9 Larynx, unspecified	0.704	0.296	0.000
C34.0 Main bronchus	0.704	0.296	0.000
G25 Other extrapyramidal and movement disorders	0.704	0.296	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.703	0.296	0.000
W17 Other fall from one level to another	0.703	0.297	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.703	0.297	0.000
W15 Fall from cliff	0.703	0.297	0.000
W14 Fall from tree	0.703	0.297	0.000
W12 Fall on and from scaffolding	0.703	0.297	0.000
W09 Fall involving playground equipment	0.703	0.297	0.000
W05 Fall involving wheelchair	0.703	0.297	0.000
W04 Fall while being carried or supported by other persons	0.703	0.297	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.703	0.297	0.000
W00 Fall on same level involving ice and snow	0.703	0.297	0.000
M22 Disorders of patella	0.703	0.297	0.000
D37.2 Small intestine	0.702	0.298	0.000
R86 Abnormal findings in specimens from male genital organs	0.702	0.298	0.000
I72.3 Aneurysm of iliac artery	0.701	0.299	0.000
J60-J70 Lung diseases due to external agents	0.701	0.299	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.700	0.300	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.700	0.300	0.000
M25.2 Flail joint	0.699	0.301	0.000
M25.1 Fistula of joint	0.699	0.301	0.000
Q80-Q89 Other congenital malformations	0.699	0.301	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.698	0.302	0.000
I95 Hypotension	0.697	0.302	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.697	0.303	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.697	0.303	0.000
J41 Simple and mucopurulent chronic bronchitis	0.697	0.303	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.697	0.303	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.697	0.303	0.000
F30 Manic episode	0.697	0.303	0.000
H72 Perforation of tympanic membrane	0.696	0.304	0.000
F44 Dissociative [conversion] disorders	0.696	0.304	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.695	0.305	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.695	0.305	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.694	0.306	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.694	0.306	0.000
F99-F99 Unspecified mental disorder	0.694	0.306	0.000
F33.9 Recurrent depressive disorder, unspecified	0.693	0.306	0.000
C32.0 Glottis	0.693	0.307	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.692	0.307	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.691	0.309	0.000
U80 Agent resistant to penicillin and related antibiotics	0.691	0.309	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.690	0.309	0.000
M81.9 Osteoporosis, unspecified	0.690	0.310	0.000
W19.8 Other specified place	0.690	0.310	0.000
W19.5 Trade and service area	0.690	0.310	0.000
W19.0 Home	0.690	0.310	0.000
W19.7 Farm	0.690	0.310	0.000
W19.6 Industrial and construction area	0.690	0.310	0.000
W19.1 Residential institution	0.690	0.310	0.000
R61 Hyperhidrosis	0.690	0.310	0.000
M25.79 Osteophyte (Site unspecified)	0.690	0.310	0.000
M25.73 Osteophyte (Forearm)	0.690	0.310	0.000
M25.70 Osteophyte (Multiple sites)	0.690	0.310	0.000
Y40.9 Systemic antibiotic, unspecified	0.689	0.311	0.000
C18.0 Caecum	0.688	0.312	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.687	0.313	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.687	0.313	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.687	0.313	0.000
S00-S09 Injuries to the head	0.686	0.314	0.000
M83 Adult osteomalacia	0.685	0.314	0.000
D37.7 Other digestive organs	0.684	0.316	0.000
F40.0 Agoraphobia	0.682	0.318	0.000
D37.4 Colon	0.682	0.318	0.000
R59.0 Localised enlarged lymph nodes	0.681	0.319	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.681	0.319	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.680	0.319	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.680	0.320	0.000
R59.9 Enlarged lymph nodes, unspecified	0.679	0.321	0.000
R68 Other general symptoms and signs	0.679	0.321	0.000
H74.4 Polyp of middle ear	0.678	0.321	0.000
H10 Conjunctivitis	0.678	0.322	0.000
C69 Malignant neoplasm of eye and adnexa	0.678	0.322	0.000
I61.8 Other intracerebral haemorrhage	0.678	0.322	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.678	0.322	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.678	0.322	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.678	0.322	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.678	0.322	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.678	0.322	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.678	0.322	0.000
J20.9 Acute bronchitis, unspecified	0.677	0.322	0.000
M25.74 Osteophyte (Hand)	0.677	0.323	0.000
F68 Other disorders of adult personality and behaviour	0.676	0.323	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.676	0.323	0.000
F65 Disorders of sexual preference	0.676	0.323	0.000
F63 Habit and impulse disorders	0.676	0.323	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.676	0.323	0.000
F69 Unspecified disorder of adult personality and behaviour	0.676	0.323	0.000
F61 Mixed and other personality disorders	0.676	0.323	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.676	0.324	0.000
D46 Myelodysplastic syndromes	0.676	0.324	0.000
H53.0 Amblyopia ex anopsia	0.676	0.324	0.000
T33-T35 Frostbite	0.674	0.326	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.674	0.326	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.674	0.326	0.000
T00-T07 Injuries involving multiple body regions	0.674	0.326	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.674	0.326	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.674	0.326	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.674	0.326	0.000
M20.2 Hallux rigidus	0.673	0.327	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.673	0.327	0.000
R43 Disturbances of smell and taste	0.672	0.328	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328	0.000
Q35-Q37 Cleft lip and cleft palate	0.672	0.328	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.672	0.328	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.672	0.328	0.000
Q00-Q07 Congenital malformations of the nervous system	0.672	0.328	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.672	0.328	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.672	0.328	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.672	0.328	0.000
I72.2 Aneurysm of renal artery	0.672	0.328	0.000
I72.1 Aneurysm of artery of upper extremity	0.672	0.328	0.000
M34 Systemic sclerosis	0.670	0.330	0.000
M13 Other arthritis	0.669	0.331	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.669	0.331	0.000
H73.1 Chronic myringitis	0.669	0.331	0.000
H73.0 Acute myringitis	0.669	0.331	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.668	0.331	0.000
M81.4 Drug-induced osteoporosis	0.668	0.332	0.000
R45 Symptoms and signs involving emotional state	0.668	0.332	0.000
H91.3 Deaf mutism, not elsewhere classified	0.668	0.332	0.000
H91.2 Sudden idiopathic hearing loss	0.668	0.332	0.000
H91.1 Presbycusis	0.668	0.332	0.000
H91.0 Ototoxic hearing loss	0.668	0.332	0.000
S50 Superficial injury of forearm	0.668	0.332	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.668	0.332	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.666	0.334	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.665	0.335	0.000
S70-S79 Injuries to the hip and thigh	0.665	0.335	0.000
Q61.3 Polycystic kidney, unspecified	0.665	0.335	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.664	0.336	0.000
M20.0 Deformity of finger(s)	0.664	0.336	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.664	0.336	0.000
I77.5 Necrosis of artery	0.664	0.336	0.000
I77.4 Coeliac artery compression syndrome	0.664	0.336	0.000
I77.3 Arterial fibromuscular dysplasia	0.664	0.336	0.000
I77.2 Rupture of artery	0.664	0.336	0.000
W18 Other fall on same level	0.663	0.337	0.000
F80-F89 Disorders of psychological development	0.663	0.337	0.000
H66 Suppurative and unspecified otitis media	0.663	0.337	0.000
D40.1 Testis	0.662	0.338	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.660	0.340	0.000
H65.2 Chronic serous otitis media	0.660	0.340	0.000
Q50-Q56 Congenital malformations of genital organs	0.660	0.340	0.000
M25.72 Osteophyte (Upper arm)	0.660	0.340	0.000
H54 Blindness and low vision	0.659	0.341	0.000
Y40.0 Penicillins	0.658	0.342	0.000
S90 Superficial injury of ankle and foot	0.658	0.342	0.000
W10 Fall on and from stairs and steps	0.657	0.342	0.000
J94.2 Haemothorax	0.657	0.343	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.656	0.344	0.000
R62 Lack of expected normal physiological development	0.656	0.344	0.000
R64 Cachexia	0.656	0.344	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.655	0.345	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.655	0.345	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.655	0.345	0.000
I67.5 Moyamoya disease	0.655	0.345	0.000
I67.4 Hypertensive encephalopathy	0.655	0.345	0.000
I67.3 Progressive vascular leukoencephalopathy	0.655	0.345	0.000
S56 Injury of muscle and tendon at forearm level	0.655	0.345	0.000
I77.1 Stricture of artery	0.655	0.345	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.654	0.346	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.654	0.346	0.000
C18.7 Sigmoid colon	0.654	0.346	0.000
M65 Synovitis and tenosynovitis	0.652	0.348	0.000
H57.1 Ocular pain	0.651	0.349	0.000
M24.2 Disorder of ligament	0.651	0.349	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.651	0.349	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.650	0.350	0.000
I69.3 Sequelae of cerebral infarction	0.650	0.350	0.000
V48 Car occupant injured in noncollision transport accident	0.650	0.350	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.650	0.350	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.650	0.350	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.650	0.350	0.000
D47.4 Osteomyelofibrosis	0.650	0.350	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.650	0.350	0.000
S51.9 Open wound of forearm, part unspecified	0.650	0.350	0.000
S68 Traumatic amputation of wrist and hand	0.649	0.351	0.000
J84 Other interstitial pulmonary diseases	0.647	0.353	0.000
F38 Other mood [affective] disorders	0.646	0.354	0.000
F34 Persistent mood [affective] disorders	0.646	0.354	0.000
F39 Unspecified mood [affective] disorder	0.646	0.354	0.000
R46 Symptoms and signs involving appearance and behaviour	0.646	0.354	0.000
R25 Abnormal involuntary movements	0.646	0.354	0.000
G70-G73 Diseases of myoneural junction and muscle	0.644	0.356	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.644	0.356	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.644	0.356	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.643	0.356	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.644	0.356	0.000
F60.8 Other specific personality disorders	0.643	0.357	0.000
F60.7 Dependent personality disorder	0.643	0.357	0.000
F60.6 Anxious [avoidant] personality disorder	0.643	0.357	0.000
F60.5 Anankastic personality disorder	0.643	0.357	0.000
F60.4 Histrionic personality disorder	0.643	0.357	0.000
F60.2 Dissocial personality disorder	0.643	0.357	0.000
F60.1 Schizoid personality disorder	0.643	0.357	0.000
F60.0 Paranoid personality disorder	0.643	0.357	0.000
I70 Atherosclerosis	0.642	0.357	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.642	0.358	0.000
C17 Malignant neoplasm of small intestine	0.641	0.359	0.000
C23 Malignant neoplasm of gallbladder	0.641	0.359	0.000
Q61.0 Congenital single renal cyst	0.641	0.359	0.000
D40.0 Prostate	0.640	0.360	0.000
M25.51 Pain in joint (Shoulder region)	0.640	0.360	0.000
M31 Other necrotising vasculopathies	0.640	0.360	0.000
J43.8 Other emphysema	0.640	0.360	0.000
J43.2 Centrilobular emphysema	0.640	0.360	0.000
J43.1 Panlobular emphysema	0.640	0.360	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations