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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62007678
log Bayes Factor = 8.84102
Chromosome 14   position 103,870,716  (GRCh37) Explore rs62007678 on Ensembl!
Variant rs62007678 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
M23 Internal derangement of knee
0.998 0.002 0.000
Chapter II Neoplasms
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
M24 Other specific joint derangements
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.989 0.011 0.000
C79 Secondary malignant neoplasm of other sites
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
M23.8 Other internal derangements of knee
0.980 0.020 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.976 0.024 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.973 0.027 0.000
M23.3 Other meniscus derangements
0.967 0.033 0.000
M65-M68 Disorders of synovium and tendon
0.958 0.042 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.958 0.042 0.000
D50-D53 Nutritional anaemias
0.953 0.047 0.000
M06 Other rheumatoid arthritis
0.950 0.050 0.000
C80 Malignant neoplasm without specification of site
0.947 0.053 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.947 0.053 0.000
M65 Synovitis and tenosynovitis
0.929 0.071 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.924 0.076 0.000
M24.1 Other articular cartilage disorders
0.922 0.078 0.000
M15-M19 Arthrosis
0.920 0.080 0.000
C51-C58 Malignant neoplasms of female genital organs
0.915 0.085 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.914 0.086 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.913 0.087 0.000
D50 Iron deficiency anaemia
0.911 0.089 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.910 0.090 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.910 0.090 0.000
O42 Premature rupture of membranes
0.907 0.093 0.000
M06.0 Seronegative rheumatoid arthritis
0.905 0.095 0.000
M17 Gonarthrosis [arthrosis of knee]
0.902 0.098 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.900 0.100 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.899 0.101 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.897 0.103 0.000
M24.0 Loose body in joint
0.896 0.104 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.895 0.105 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.891 0.109 0.000
O48 Prolonged pregnancy
0.887 0.113 0.000
D50.8 Other iron deficiency anaemias
0.886 0.114 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.882 0.118 0.000
C54 Malignant neoplasm of corpus uteri
0.881 0.119 0.000
O60-O75 Complications of labour and delivery
0.874 0.126 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.874 0.126 0.000
S00-S09 Injuries to the head
0.871 0.129 0.000
L40-L45 Papulosquamous disorders
0.870 0.130 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.867 0.133 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.867 0.133 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.865 0.135 0.000
C54.1 Endometrium
0.858 0.142 0.000
M17.9 Gonarthrosis, unspecified
0.856 0.144 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.850 0.150 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.849 0.151 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.848 0.152 0.000
D51 Vitamin B12 deficiency anaemia
0.847 0.153 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.846 0.154 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.844 0.156 0.000
M25 Other joint disorders, not elsewhere classified
0.841 0.159 0.000
O00-O08 Pregnancy with abortive outcome
0.839 0.161 0.000
D00-D09 In situ neoplasms
0.839 0.161 0.000
M13 Other arthritis
0.839 0.161 0.000
M22 Disorders of patella
0.837 0.163 0.000
O47 False labour
0.837 0.163 0.000
S90-S99 Injuries to the ankle and foot
0.833 0.167 0.000
L90 Atrophic disorders of skin
0.827 0.173 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.827 0.173 0.000
T51 Toxic effect of alcohol
0.824 0.176 0.000
Chapter V Mental and behavioural disorders
0.823 0.177 0.000
S10-S19 Injuries to the neck
0.819 0.181 0.000
M24.7 Protrusio acetabuli
0.818 0.182 0.000
L82 Seborrhoeic keratosis
0.815 0.185 0.000
Chapter IX Diseases of the circulatory system
0.815 0.185 0.000
M17.1 Other primary gonarthrosis
0.814 0.186 0.000
M21 Other acquired deformities of limbs
0.813 0.187 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.812 0.188 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.811 0.189 0.000
Chapter I Certain infectious and parasitic diseases
0.811 0.189 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.810 0.190 0.000
M60-M63 Disorders of muscles
0.810 0.190 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.808 0.192 0.000
M24.6 Ankylosis of joint
0.807 0.193 0.000
L40 Psoriasis
0.807 0.193 0.000
O43 Placental disorders
0.806 0.194 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.806 0.194 0.000
T40.2 Other opioids
0.804 0.196 0.000
M24.2 Disorder of ligament
0.802 0.198 0.000
I60-I69 Cerebrovascular diseases
0.802 0.198 0.000
M31 Other necrotising vasculopathies
0.802 0.198 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.802 0.198 0.000
Chapter VII Diseases of the eye and adnexa
0.802 0.198 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.801 0.199 0.000
D55-D59 Haemolytic anaemias
0.801 0.199 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.801 0.199 0.000
M06.9 Rheumatoid arthritis, unspecified
0.799 0.201 0.000
M07 Psoriatic and enteropathic arthropathies
0.798 0.202 0.000
C78.0 Secondary malignant neoplasm of lung
0.797 0.203 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.796 0.204 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.794 0.206 0.000
M86-M90 Other osteopathies
0.793 0.207 0.000
M35 Other systemic involvement of connective tissue
0.792 0.208 0.000
L90.5 Scar conditions and fibrosis of skin
0.792 0.208 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.790 0.210 0.000
T40.4 Other synthetic narcotics
0.789 0.211 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.789 0.211 0.000
S02 Fracture of skull and facial bones
0.788 0.212 0.000
S09 Other and unspecified injuries of head
0.788 0.212 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.785 0.214 0.000
T00-T07 Injuries involving multiple body regions
0.778 0.222 0.000
O80-O84 Delivery
0.776 0.224 0.000
L40.5 Arthropathic psoriasis
0.774 0.226 0.000
M11 Other crystal arthropathies
0.772 0.228 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.772 0.228 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.772 0.228 0.000
M24.02 Loose body in joint (Upper arm)
0.770 0.230 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.769 0.230 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.769 0.231 0.000
M00-M03 Infectious arthropathies
0.767 0.233 0.000
S05 Injury of eye and orbit
0.766 0.234 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.766 0.234 0.000
T39.1 4-Aminophenol derivatives
0.764 0.236 0.000
I69 Sequelae of cerebrovascular disease
0.764 0.236 0.000
T58 Toxic effect of carbon monoxide
0.763 0.237 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.762 0.237 0.000
S60-S69 Injuries to the wrist and hand
0.761 0.239 0.000
L85 Other epidermal thickening
0.760 0.240 0.000
C79.6 Secondary malignant neoplasm of ovary
0.759 0.241 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.756 0.244 0.000
H30-H36 Disorders of choroid and retina
0.755 0.245 0.000
M24.07 Loose body in joint (Ankle and foot)
0.755 0.245 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.753 0.247 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.751 0.249 0.000
C64-C68 Malignant neoplasms of urinary tract
0.751 0.249 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.749 0.251 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.749 0.251 0.000
C80.9 Malignant neoplasm, unspecified
0.748 0.252 0.000
O72 Postpartum haemorrhage
0.748 0.252 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.747 0.253 0.000
D75 Other diseases of blood and blood-forming organs
0.746 0.253 0.000
T51.0 Ethanol
0.746 0.254 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.745 0.255 0.000
M23.9 Internal derangement of knee, unspecified
0.744 0.256 0.000
M45-M49 Spondylopathies
0.743 0.257 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.742 0.258 0.000
O42.9 Premature rupture of membranes, unspecified
0.741 0.259 0.000
M14 Arthropathies in other diseases classified elsewhere
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.737 0.263 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.736 0.264 0.000
M80-M85 Disorders of bone density and structure
0.736 0.264 0.000
I63 Cerebral infarction
0.735 0.265 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.735 0.265 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.733 0.267 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.732 0.268 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.731 0.269 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.729 0.271 0.000
S09.9 Unspecified injury of head
0.729 0.271 0.000
C78.7 Secondary malignant neoplasm of liver
0.728 0.272 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.727 0.273 0.000
M19 Other arthrosis
0.726 0.274 0.000
C07 Malignant neoplasm of parotid gland
0.725 0.275 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.724 0.276 0.000
B95-B98 Bacterial, viral and other infectious agents
0.721 0.279 0.000
L89 Decubitus ulcer
0.719 0.281 0.000
M25.9 Joint disorder, unspecified
0.719 0.281 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.719 0.281 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.718 0.282 0.000
H35 Other retinal disorders
0.718 0.282 0.000
O30 Multiple gestation
0.718 0.282 0.000
O70 Perineal laceration during delivery
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
M23.1 Discoid meniscus (congenital)
0.715 0.285 0.000
M23.0 Cystic meniscus
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
M24.9 Joint derangement, unspecified
0.713 0.287 0.000
M24.5 Contracture of joint
0.713 0.287 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.713 0.287 0.000
D52 Folate deficiency anaemia
0.712 0.287 0.000
O32.2 Maternal care for transverse and oblique lie
0.712 0.287 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.711 0.289 0.000
M34 Systemic sclerosis
0.711 0.289 0.000
C04 Malignant neoplasm of floor of mouth
0.711 0.289 0.000
Chapter VIII Diseases of the ear and mastoid process
0.711 0.289 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.710 0.290 0.000
O45 Premature separation of placenta [abruptio placentae]
0.709 0.291 0.000
O33 Maternal care for known or suspected disproportion
0.709 0.291 0.000
O31 Complications specific to multiple gestation
0.709 0.291 0.000
O40 Polyhydramnios
0.709 0.291 0.000
O02 Other abnormal products of conception
0.709 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.709 0.291 0.000
L81 Other disorders of pigmentation
0.709 0.291 0.000
C09 Malignant neoplasm of tonsil
0.707 0.293 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.707 0.293 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.707 0.293 0.000
M12 Other specific arthropathies
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.294 0.000
M08 Juvenile arthritis
0.706 0.294 0.000
D05 Carcinoma in situ of breast
0.704 0.296 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.702 0.298 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.702 0.298 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.702 0.298 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.702 0.298 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.702 0.298 0.000
S80-S89 Injuries to the knee and lower leg
0.701 0.299 0.000
O44 Placenta praevia
0.700 0.300 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.700 0.300 0.000
T40.6 Other and unspecified narcotics
0.700 0.300 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.699 0.300 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.300 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.699 0.300 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.699 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.300 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.699 0.300 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.699 0.300 0.000
T36 Poisoning by systemic antibiotics
0.699 0.300 0.000
I63.9 Cerebral infarction, unspecified
0.699 0.301 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.699 0.301 0.000
H25-H28 Disorders of lens
0.699 0.301 0.000
M23.4 Loose body in knee
0.698 0.301 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.698 0.302 0.000
D75.1 Secondary polycythaemia
0.696 0.304 0.000
M23.37 Other meniscus derangements-Capsular lig
0.694 0.306 0.000
L20-L30 Dermatitis and eczema
0.694 0.306 0.000
M10 Gout
0.694 0.306 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.693 0.307 0.000
O16 Unspecified maternal hypertension
0.693 0.307 0.000
M13.0 Polyarthritis, unspecified
0.693 0.307 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.693 0.307 0.000
C10 Malignant neoplasm of oropharynx
0.692 0.308 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.692 0.308 0.000
O32.8 Maternal care for other malpresentation of foetus
0.691 0.309 0.000
C51 Malignant neoplasm of vulva
0.689 0.311 0.000
M25.4 Effusion of joint
0.689 0.311 0.000
L91 Hypertrophic disorders of skin
0.687 0.313 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.687 0.313 0.000
M66 Spontaneous rupture of synovium and tendon
0.687 0.313 0.000
S05.8 Other injuries of eye and orbit
0.687 0.313 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.687 0.313 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.687 0.313 0.000
M65.8 Other synovitis and tenosynovitis
0.686 0.314 0.000
S12 Fracture of neck
0.686 0.314 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.686 0.314 0.000
S02.1 Fracture of base of skull
0.685 0.315 0.000
A30-A49 Other bacterial diseases
0.685 0.315 0.000
O43.1 Malformation of placenta
0.685 0.315 0.000
M67 Other disorders of synovium and tendon
0.684 0.316 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.684 0.316 0.000
D53 Other nutritional anaemias
0.683 0.317 0.000
Chapter XXII Codes for special purposes
0.682 0.318 0.000
O46.9 Antepartum haemorrhage, unspecified
0.682 0.318 0.000
I71 Aortic aneurysm and dissection
0.682 0.318 0.000
M06.8 Other specified rheumatoid arthritis
0.681 0.319 0.000
M06.4 Inflammatory polyarthropathy
0.681 0.319 0.000
M06.3 Rheumatoid nodule
0.681 0.319 0.000
M06.2 Rheumatoid bursitis
0.681 0.319 0.000
M06.1 Adult-onset Still's disease
0.681 0.319 0.000
I62 Other nontraumatic intracranial haemorrhage
0.681 0.319 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.681 0.319 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.680 0.320 0.000
C79.2 Secondary malignant neoplasm of skin
0.680 0.320 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.679 0.320 0.000
L10-L14 Bullous disorders
0.679 0.321 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
D59 Acquired haemolytic anaemia
0.678 0.322 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.678 0.322 0.000
L93 Lupus erythematosus
0.677 0.322 0.000
M17.0 Primary gonarthrosis, bilateral
0.677 0.323 0.000
B50-B64 Protozoal diseases
0.677 0.323 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.676 0.324 0.000
O71 Other obstetric trauma
0.675 0.325 0.000
M62 Other disorders of muscle
0.674 0.325 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.673 0.327 0.000
M24.26 Disorder of ligament (Lower leg)
0.673 0.327 0.000
D04 Carcinoma in situ of skin
0.673 0.327 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.672 0.328 0.000
M35.3 Polymyalgia rheumatica
0.671 0.329 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.671 0.329 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.670 0.330 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.669 0.331 0.000
M21.4 Flat foot [pes planus] (acquired)
0.669 0.331 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.668 0.332 0.000
M13.9 Arthritis, unspecified
0.668 0.332 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.667 0.333 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
O82 Single delivery by Caesarean section
0.667 0.333 0.000
M65.2 Calcific tendinitis
0.666 0.334 0.000
M65.1 Other infective (teno)synovitis
0.666 0.334 0.000
M65.0 Abscess of tendon sheath
0.666 0.334 0.000
O47.0 False labour before 37 completed weeks of gestation
0.665 0.334 0.000
C01 Malignant neoplasm of base of tongue
0.664 0.336 0.000
M07.3 Other psoriatic arthropathies
0.663 0.337 0.000
M17.3 Other posttraumatic gonarthrosis
0.663 0.337 0.000
M22.2 Patellofemoral disorders
0.661 0.338 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.661 0.339 0.000
M24.18 Other articular cartilage disorders (Other)
0.661 0.339 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.661 0.339 0.000
M24.14 Other articular cartilage disorders (Hand)
0.661 0.339 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.661 0.339 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.661 0.339 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.661 0.339 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.661 0.339 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.661 0.339 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.660 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.660 0.340 0.000
M15 Polyarthrosis
0.660 0.340 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.660 0.340 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
M50-M54 Other dorsopathies
0.658 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.658 0.342 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.658 0.342 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.656 0.344 0.000
C58 Malignant neoplasm of placenta
0.656 0.344 0.000
C52 Malignant neoplasm of vagina
0.656 0.344 0.000
M21.6 Other acquired deformities of ankle and foot
0.656 0.344 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.655 0.344 0.000
T40.8 Lysergide [LSD]
0.655 0.344 0.000
T40.7 Cannabis (derivatives)
0.655 0.344 0.000
T40.5 Cocaine
0.655 0.344 0.000
T40.3 Methadone
0.655 0.344 0.000
T40.1 Heroin
0.655 0.344 0.000
T40.0 Opium
0.655 0.344 0.000
H53-H54 Visual disturbances and blindness
0.655 0.345 0.000
T65 Toxic effect of other and unspecified substances
0.654 0.345 0.000
T62 Toxic effect of other noxious substances eaten as food
0.654 0.345 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.654 0.345 0.000
T60 Toxic effect of pesticides
0.654 0.345 0.000
T59 Toxic effect of other gases, fumes and vapours
0.654 0.345 0.000
T57 Toxic effect of other inorganic substances
0.654 0.345 0.000
T56 Toxic effect of metals
0.654 0.345 0.000
T54 Toxic effect of corrosive substances
0.654 0.345 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.654 0.345 0.000
T52 Toxic effect of organic solvents
0.654 0.345 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.654 0.345 0.000
T55 Toxic effect of soaps and detergents
0.654 0.345 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.654 0.346 0.000
O00 Ectopic pregnancy
0.654 0.346 0.000
S50-S59 Injuries to the elbow and forearm
0.653 0.347 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.347 0.000
D50.1 Sideropenic dysphagia
0.653 0.347 0.000
O03 Spontaneous abortion
0.653 0.347 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.652 0.347 0.000
L94 Other localised connective tissue disorders
0.652 0.347 0.000
L87 Transepidermal elimination disorders
0.652 0.347 0.000
L88 Pyoderma gangrenosum
0.652 0.347 0.000
L86 Keratoderma in diseases classified elsewhere
0.652 0.347 0.000
L83 Acanthosis nigricans
0.652 0.347 0.000
L80 Vitiligo
0.652 0.347 0.000
L43 Lichen planus
0.651 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.651 0.349 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.651 0.349 0.000
I77 Other disorders of arteries and arterioles
0.651 0.349 0.000
M05 Seropositive rheumatoid arthritis
0.650 0.350 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.650 0.350 0.000
S02.6 Fracture of mandible
0.650 0.350 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.649 0.351 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.649 0.351 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.649 0.351 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.649 0.351 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.649 0.351 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.649 0.351 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.649 0.351 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.649 0.351 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.649 0.351 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.648 0.352 0.000
D03 Melanoma in situ
0.648 0.352 0.000
M17.5 Other secondary gonarthrosis
0.647 0.353 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.647 0.353 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.647 0.353 0.000
L50-L54 Urticaria and erythema
0.646 0.354 0.000
M31.3 Wegener's granulomatosis
0.645 0.355 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.644 0.356 0.000
C13 Malignant neoplasm of hypopharynx
0.644 0.356 0.000
C11 Malignant neoplasm of nasopharynx
0.644 0.356 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.644 0.356 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.644 0.356 0.000
C05 Malignant neoplasm of palate
0.644 0.356 0.000
C03 Malignant neoplasm of gum
0.644 0.356 0.000
C00 Malignant neoplasm of lip
0.644 0.356 0.000
C12 Malignant neoplasm of pyriform sinus
0.644 0.356 0.000
M24.09 Loose body in joint (Site unspecified)
0.643 0.357 0.000
M24.08 Loose body in joint (Other)
0.643 0.357 0.000
M24.06 Loose body in joint-Lower leg
0.643 0.357 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.643 0.357 0.000
M24.04 Loose body in joint (Hand)
0.643 0.357 0.000
M24.03 Loose body in joint (Forearm)
0.643 0.357 0.000
M24.01 Loose body in joint (Shoulder region)
0.643 0.357 0.000
M24.00 Loose body in joint (Multiple sites)
0.643 0.357 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.642 0.358 0.000
H35.3 Degeneration of macula and posterior pole
0.641 0.359 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.640 0.360 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.640 0.360 0.000
M21.2 Flexion deformity
0.640 0.360 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.639 0.361 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.639 0.361 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.639 0.361 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.639 0.361 0.000
S92 Fracture of foot, except ankle
0.638 0.362 0.000
M25.8 Other specified joint disorders
0.638 0.362 0.000
M93 Other osteochondropathies
0.637 0.363 0.000
M46 Other inflammatory spondylopathies
0.637 0.363 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.637 0.363 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.635 0.364 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.635 0.365 0.000
C78.2 Secondary malignant neoplasm of pleura
0.635 0.365 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.634 0.366 0.000
S64 Injury of nerves at wrist and hand level
0.633 0.367 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.633 0.367 0.000
T51.9 Alcohol, unspecified
0.633 0.367 0.000
O32.6 Maternal care for compound presentation
0.632 0.368 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.632 0.368 0.000
O32.4 Maternal care for high head at term
0.632 0.368 0.000
O32.3 Maternal care for face, brow and chin presentation
0.632 0.368 0.000
O32.0 Maternal care for unstable lie
0.632 0.368 0.000
M22.3 Other derangements of patella
0.632 0.368 0.000
C54.9 Corpus uteri, unspecified
0.632 0.368 0.000
C54.8 Overlapping lesion of corpus uteri
0.632 0.368 0.000
C54.3 Fundus uteri
0.632 0.368 0.000
C54.2 Myometrium
0.632 0.368 0.000
C54.0 Isthmus uteri
0.632 0.368 0.000
M88 Paget's disease of bone [osteitis deformans]
0.632 0.368 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.632 0.368 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.632 0.368 0.000
M22.4 Chondromalacia patellae
0.631 0.369 0.000
O32.1 Maternal care for breech presentation
0.631 0.369 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.631 0.369 0.000
S02.4 Fracture of malar and maxillary bones
0.631 0.369 0.000
O70.1 Second degree perineal laceration during delivery
0.629 0.371 0.000
Q50-Q56 Congenital malformations of genital organs
0.629 0.371 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.629 0.371 0.000
O02.1 Missed abortion
0.629 0.371 0.000
M22.8 Other disorders of patella
0.628 0.372 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.628 0.372 0.000
M25.0 Haemarthrosis
0.627 0.372 0.000
F29 Unspecified nonorganic psychosis
0.627 0.373 0.000
O74 Complications of anaesthesia during labour and delivery
0.627 0.373 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.627 0.373 0.000
O61 Failed induction of labour
0.627 0.373 0.000
O60 Preterm delivery
0.627 0.373 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.626 0.373 0.000
T39.4 Antirheumatics, not elsewhere classified
0.626 0.373 0.000
T39.2 Pyrazolone derivatives
0.626 0.373 0.000
O41 Other disorders of amniotic fluid and membranes
0.625 0.374 0.000
T63 Toxic effect of contact with venomous animals
0.625 0.375 0.000
S08 Traumatic amputation of part of head
0.624 0.375 0.000
S07 Crushing injury of head
0.624 0.375 0.000
S04 Injury of cranial nerves
0.624 0.375 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.624 0.375 0.000
S60 Superficial injury of wrist and hand
0.624 0.376 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.624 0.376 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.624 0.376 0.000
O73 Retained placenta and membranes, without haemorrhage
0.624 0.376 0.000
L44 Other papulosquamous disorders
0.623 0.376 0.000
L41 Parapsoriasis
0.623 0.376 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.623 0.376 0.000
L42 Pityriasis rosea
0.623 0.376 0.000
T00 Superficial injuries involving multiple body regions
0.623 0.376 0.000
F60-F69 Disorders of adult personality and behaviour
0.623 0.377 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.623 0.377 0.000
L84 Corns and callosities
0.622 0.377 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.622 0.378 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.622 0.378 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.622 0.378 0.000
O97 Death from sequelae of direct obstetric causes
0.622 0.378 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.622 0.378 0.000
O95 Obstetric death of unspecified cause
0.622 0.378 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.622 0.378 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.621 0.379 0.000
S70-S79 Injuries to the hip and thigh
0.620 0.379 0.000
O72.1 Other immediate postpartum haemorrhage
0.620 0.380 0.000
M11.2 Other chondrocalcinosis
0.620 0.380 0.000
H54 Blindness and low vision
0.619 0.381 0.000
H25 Senile cataract
0.619 0.381 0.000
M92 Other juvenile osteochondrosis
0.618 0.382 0.000
L85.8 Other specified epidermal thickening
0.618 0.382 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.616 0.383 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.616 0.384 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.616 0.384 0.000
M23.5 Chronic instability of knee
0.614 0.386 0.000
Q60-Q64 Congenital malformations of the urinary system
0.614 0.386 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.613 0.387 0.000
S99 Other and unspecified injuries of ankle and foot
0.612 0.387 0.000
S02.10 Fracture of base of skull (closed)
0.612 0.388 0.000
M25.7 Osteophyte
0.611 0.389 0.000
H90-H95 Other disorders of ear
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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