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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62109865
log Bayes Factor = 0.999309
Chromosome 19   position 13,037,734  (GRCh37) Explore rs62109865 on Ensembl!
Variant rs62109865 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.889 0.111 0.000
Chapter VI Diseases of the nervous system
0.886 0.114 0.000
M50-M54 Other dorsopathies
0.883 0.117 0.000
# Top node
0.879 0.121 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.876 0.124 0.000
G30-G32 Other degenerative diseases of the nervous system
0.875 0.125 0.000
G30 Alzheimer's disease
0.872 0.128 0.000
G30.9 Alzheimer's disease, unspecified
0.860 0.140 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.859 0.141 0.000
M60-M63 Disorders of muscles
0.858 0.142 0.000
E70-E90 Metabolic disorders
0.853 0.147 0.000
G82 Paraplegia and tetraplegia
0.847 0.153 0.000
M40-M43 Deforming dorsopathies
0.846 0.154 0.000
E10-E14 Diabetes mellitus
0.846 0.154 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
M54 Dorsalgia
0.843 0.157 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.837 0.163 0.000
M51 Other intervertebral disk disorders
0.829 0.171 0.000
M62 Other disorders of muscle
0.829 0.171 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.829 0.171 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.823 0.177 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.815 0.185 0.000
M54.3 Sciatica
0.815 0.185 0.000
G82.1 Spastic paraplegia
0.811 0.189 0.000
Q60-Q64 Congenital malformations of the urinary system
0.811 0.189 0.000
Chapter V Mental and behavioural disorders
0.811 0.189 0.000
M62.8 Other specified disorders of muscle
0.809 0.191 0.000
M43 Other deforming dorsopathies
0.807 0.193 0.000
O00-O08 Pregnancy with abortive outcome
0.805 0.195 0.000
M45-M49 Spondylopathies
0.804 0.196 0.000
M86-M90 Other osteopathies
0.804 0.196 0.000
M51.2 Other specified intervertebral disk displacement
0.800 0.200 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.798 0.202 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.797 0.203 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.792 0.208 0.000
E14 Unspecified diabetes mellitus
0.791 0.209 0.000
E89.0 Postprocedural hypothyroidism
0.791 0.209 0.000
M43.1 Spondylolisthesis
0.782 0.218 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.776 0.224 0.000
Q61 Cystic kidney disease
0.770 0.230 0.000
G30.0 Alzheimer's disease with early onset
0.770 0.230 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.766 0.234 0.000
M54.39 Sciatica (Site unspecified)
0.766 0.234 0.000
E83 Disorders of mineral metabolism
0.762 0.238 0.000
G82.5 Tetraplegia, unspecified
0.761 0.239 0.000
O04 Medical abortion
0.759 0.241 0.000
E50-E64 Other nutritional deficiencies
0.759 0.241 0.000
Chapter XXII Codes for special purposes
0.758 0.242 0.000
M89 Other disorders of bone
0.757 0.243 0.000
Chapter X Diseases of the respiratory system
0.746 0.254 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.746 0.254 0.000
M53 Other dorsopathies, not elsewhere classified
0.742 0.258 0.000
F00 Dementia in Alzheimer's disease
0.742 0.258 0.000
E78.5 Hyperlipidaemia, unspecified
0.738 0.262 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.730 0.270 0.000
M48 Other spondylopathies
0.730 0.270 0.000
M54.5 Low back pain
0.729 0.271 0.000
O04.9 Complete or unspecified, without complication
0.728 0.272 0.000
E11 Non-insulin-dependent diabetes mellitus
0.726 0.274 0.000
G35 Multiple sclerosis
0.723 0.277 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.722 0.278 0.000
J09-J18 Influenza and pneumonia
0.722 0.278 0.000
Q61.2 Polycystic kidney, adult type
0.720 0.280 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.716 0.284 0.000
J30-J39 Other diseases of upper respiratory tract
0.716 0.284 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.716 0.284 0.000
G30.8 Other Alzheimer's disease
0.715 0.285 0.000
Chapter XX External causes of morbidity and mortality
0.714 0.286 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.710 0.290 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.710 0.290 0.000
E14.3 With ophthalmic complications
0.708 0.292 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.707 0.293 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.705 0.295 0.000
E83.5 Disorders of calcium metabolism
0.704 0.296 0.000
M51.8 Other specified intervertebral disk disorders
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.297 0.000
M54.36 Sciatica (Lumbar region)
0.702 0.297 0.000
G82.4 Spastic tetraplegia
0.698 0.302 0.000
Q61.3 Polycystic kidney, unspecified
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
M80-M85 Disorders of bone density and structure
0.693 0.307 0.000
F03 Unspecified dementia
0.692 0.308 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.692 0.308 0.000
E16 Other disorders of pancreatic internal secretion
0.688 0.312 0.000
E14.9 Without complications
0.687 0.313 0.000
J38.3 Other diseases of vocal cords
0.685 0.315 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.682 0.318 0.000
E20-E35 Disorders of other endocrine glands
0.682 0.318 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.679 0.321 0.000
E11.5 With peripheral circulatory complications
0.676 0.324 0.000
M89.9 Disorder of bone, unspecified
0.676 0.324 0.000
E10 Insulin-dependent diabetes mellitus
0.674 0.326 0.000
M49 Spondylopathies in diseases classified elsewhere
0.672 0.328 0.000
M48.0 Spinal stenosis
0.669 0.331 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.667 0.333 0.000
J38.2 Nodules of vocal cords
0.667 0.333 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.666 0.334 0.000
M60 Myositis
0.663 0.337 0.000
M46 Other inflammatory spondylopathies
0.663 0.337 0.000
M62.88 Other specified disorders of muscle (Other)
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.662 0.338 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.661 0.339 0.000
Q80-Q89 Other congenital malformations
0.661 0.339 0.000
M00-M03 Infectious arthropathies
0.659 0.340 0.000
G70-G73 Diseases of myoneural junction and muscle
0.659 0.341 0.000
M40 Kyphosis and lordosis
0.659 0.341 0.000
M65-M68 Disorders of synovium and tendon
0.659 0.341 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.657 0.343 0.000
O00 Ectopic pregnancy
0.654 0.346 0.000
Q63 Other congenital malformations of kidney
0.650 0.349 0.000
M20-M25 Other joint disorders
0.650 0.350 0.000
E55 Vitamin D deficiency
0.650 0.350 0.000
G83 Other paralytic syndromes
0.649 0.351 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.647 0.353 0.000
M54.8 Other dorsalgia
0.647 0.353 0.000
O85-O92 Complications predominantly related to the puerperium
0.646 0.354 0.000
M89.0 Algoneurodystrophy
0.646 0.354 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.646 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.645 0.354 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.644 0.356 0.000
E78.1 Pure hyperglyceridaemia
0.641 0.358 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.641 0.359 0.000
E11.2 With renal complications
0.639 0.361 0.000
J60-J70 Lung diseases due to external agents
0.637 0.363 0.000
E78.8 Other disorders of lipoprotein metabolism
0.637 0.363 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.636 0.364 0.000
E83.1 Disorders of iron metabolism
0.634 0.366 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.632 0.368 0.000
M54.56 Low back pain (Lumbar region)
0.631 0.369 0.000
E89.2 Postprocedural hypoparathyroidism
0.631 0.369 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.630 0.370 0.000
J10 Influenza due to identified influenza virus
0.630 0.370 0.000
M54.9 Dorsalgia, unspecified
0.630 0.370 0.000
O02 Other abnormal products of conception
0.629 0.371 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.627 0.373 0.000
G30.1 Alzheimer's disease with late onset
0.625 0.375 0.000
M54.6 Pain in thoracic spine
0.624 0.376 0.000
J15.1 Pneumonia due to Pseudomonas
0.623 0.377 0.000
M34 Systemic sclerosis
0.623 0.377 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.623 0.377 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.623 0.377 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.622 0.378 0.000
G80 Infantile cerebral palsy
0.622 0.378 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.622 0.378 0.000
G40-G47 Episodic and paroxysmal disorders
0.622 0.378 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.621 0.379 0.000
M24 Other specific joint derangements
0.619 0.381 0.000
M51.4 Schmorl's nodes
0.616 0.384 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.615 0.385 0.000
M54.50 Low back pain (Multiple sites in spine)
0.615 0.385 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.615 0.385 0.000
M61 Calcification and ossification of muscle
0.615 0.385 0.000
E16.2 Hypoglycaemia, unspecified
0.615 0.385 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.614 0.386 0.000
E78.2 Mixed hyperlipidaemia
0.614 0.386 0.000
M48.09 Spinal stenosis (Site unspecified)
0.613 0.387 0.000
E85 Amyloidosis
0.611 0.388 0.000
E84 Cystic fibrosis
0.611 0.388 0.000
E79 Disorders of purine and pyrimidine metabolism
0.611 0.388 0.000
E77 Disorders of glycoprotein metabolism
0.611 0.388 0.000
E76 Disorders of glycosaminoglycan metabolism
0.611 0.388 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.611 0.388 0.000
E72 Other disorders of amino-acid metabolism
0.611 0.388 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.611 0.388 0.000
E70 Disorders of aromatic amino-acid metabolism
0.611 0.388 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.611 0.388 0.000
E73 Lactose intolerance
0.611 0.389 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.610 0.390 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.610 0.390 0.000
E74 Other disorders of carbohydrate metabolism
0.609 0.391 0.000
E88 Other metabolic disorders
0.608 0.392 0.000
J17 Pneumonia in diseases classified elsewhere
0.608 0.392 0.000
G82.3 Flaccid tetraplegia
0.608 0.392 0.000
G82.0 Flaccid paraplegia
0.608 0.392 0.000
M42 Spinal osteochondrosis
0.607 0.393 0.000
E12 Malnutrition-related diabetes mellitus
0.606 0.393 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.606 0.394 0.000
Q35-Q37 Cleft lip and cleft palate
0.606 0.394 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.606 0.394 0.000
M41 Scoliosis
0.606 0.394 0.000
M54.0 Panniculitis affecting regions of neck and back
0.604 0.396 0.000
Q64 Other congenital malformations of urinary system
0.603 0.397 0.000
G82.2 Paraplegia, unspecified
0.602 0.398 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.602 0.398 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.602 0.398 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.601 0.399 0.000
M50 Cervical disk disorders
0.601 0.399 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.599 0.400 0.000
J39 Other diseases of upper respiratory tract
0.599 0.401 0.000
E10.3 With ophthalmic complications
0.598 0.402 0.000
G90-G99 Other disorders of the nervous system
0.597 0.403 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.597 0.403 0.000
M90 Osteopathies in diseases classified elsewhere
0.596 0.403 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.596 0.404 0.000
M85 Other disorders of bone density and structure
0.595 0.405 0.000
M51.3 Other specified intervertebral disk degeneration
0.595 0.405 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.595 0.405 0.000
M62.9 Disorder of muscle, unspecified
0.595 0.405 0.000
M62.6 Muscle strain
0.595 0.405 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.595 0.405 0.000
M62.4 Contracture of muscle
0.595 0.405 0.000
M62.3 Immobility syndrome (paraplegic)
0.595 0.405 0.000
M62.2 Ischaemic infarction of muscle
0.595 0.405 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.595 0.405 0.000
M62.0 Diastasis of muscle
0.595 0.405 0.000
F20 Schizophrenia
0.594 0.406 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.594 0.406 0.000
O97 Death from sequelae of direct obstetric causes
0.594 0.406 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.594 0.406 0.000
O95 Obstetric death of unspecified cause
0.594 0.406 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.594 0.406 0.000
M86 Osteomyelitis
0.593 0.407 0.000
W50-W64 Exposure to animate mechanical forces
0.592 0.408 0.000
M54.37 Sciatica (Lumbosacral region)
0.591 0.409 0.000
Q00-Q07 Congenital malformations of the nervous system
0.590 0.410 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.590 0.410 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.590 0.410 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.590 0.410 0.000
M89.98 Disorder of bone, unspecified (Other)
0.590 0.410 0.000
J69 Pneumonitis due to solids and liquids
0.589 0.411 0.000
F60-F69 Disorders of adult personality and behaviour
0.587 0.412 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.585 0.415 0.000
E13 Other specified diabetes mellitus
0.585 0.415 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.585 0.415 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.584 0.416 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.584 0.416 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.584 0.416 0.000
E89.5 Postprocedural testicular hypofunction
0.584 0.416 0.000
E89.4 Postprocedural ovarian failure
0.584 0.416 0.000
E89.1 Postprocedural hypoinsulinaemia
0.584 0.416 0.000
M54.35 Sciatica (Thoracolumbar region)
0.584 0.416 0.000
M54.34 Sciatica-Thoracic
0.584 0.416 0.000
M54.33 Sciatica-Cervicothoracic
0.584 0.416 0.000
M54.32 Sciatica-Cervical
0.584 0.416 0.000
M54.31 Sciatica-Occipit-atl-axl
0.584 0.416 0.000
M54.30 Sciatica (Multiple sites in spine)
0.584 0.416 0.000
M89.8 Other specified disorders of bone
0.584 0.416 0.000
J15.4 Pneumonia due to other streptococci
0.582 0.418 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.582 0.418 0.000
O03 Spontaneous abortion
0.582 0.418 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.581 0.418 0.000
F70-F79 Mental retardation
0.581 0.418 0.000
E11.4 With neurological complications
0.581 0.419 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.580 0.420 0.000
M62.84 Other specified disorders of muscle (Hand)
0.580 0.420 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.580 0.420 0.000
O80-O84 Delivery
0.579 0.421 0.000
J38.7 Other diseases of larynx
0.579 0.421 0.000
M43.9 Deforming dorsopathy, unspecified
0.578 0.421 0.000
M43.8 Other specified deforming dorsopathies
0.578 0.421 0.000
M43.6 Torticollis
0.578 0.421 0.000
M43.5 Other recurrent vertebral subluxation
0.578 0.421 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.578 0.421 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.578 0.421 0.000
M43.2 Other fusion of spine
0.578 0.421 0.000
E53 Deficiency of other B group vitamins
0.577 0.423 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.577 0.423 0.000
O07 Failed attempted abortion
0.577 0.423 0.000
O06 Unspecified abortion
0.577 0.423 0.000
O05 Other abortion
0.577 0.423 0.000
O01 Hydatidiform mole
0.577 0.423 0.000
G12 Spinal muscular atrophy and related syndromes
0.576 0.423 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.576 0.423 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.576 0.424 0.000
G37 Other demyelinating diseases of central nervous system
0.576 0.424 0.000
E20 Hypoparathyroidism
0.575 0.425 0.000
E80.6 Other disorders of bilirubin metabolism
0.573 0.427 0.000
G00 Bacterial meningitis, not elsewhere classified
0.573 0.427 0.000
E78.6 Lipoprotein deficiency
0.572 0.428 0.000
E78.3 Hyperchylomicronaemia
0.572 0.428 0.000
E55.9 Vitamin D deficiency, unspecified
0.572 0.428 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.571 0.429 0.000
J32 Chronic sinusitis
0.570 0.430 0.000
M24.2 Disorder of ligament
0.570 0.430 0.000
X50-X57 Overexertion, travel and privation
0.570 0.430 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.570 0.430 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.569 0.431 0.000
J38.0 Paralysis of vocal cords and larynx
0.568 0.432 0.000
G36 Other acute disseminated demyelination
0.568 0.432 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.568 0.432 0.000
E14.8 With unspecified complications
0.567 0.432 0.000
E14.7 With multiple complications
0.567 0.432 0.000
E14.6 With other specified complications
0.567 0.432 0.000
E14.5 With peripheral circulatory complications
0.567 0.432 0.000
E14.4 With neurological complications
0.567 0.432 0.000
E14.2 Withrenal complications
0.567 0.432 0.000
E14.1 With ketoacidosis
0.567 0.432 0.000
E14.0 With coma
0.567 0.432 0.000
M89.04 Algoneurodystrophy (Hand)
0.567 0.433 0.000
F99-F99 Unspecified mental disorder
0.565 0.434 0.000
G60 Hereditary and idiopathic neuropathy
0.565 0.435 0.000
F02 Dementia in other diseases classified elsewhere
0.564 0.436 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.564 0.436 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.564 0.436 0.000
E61 Deficiency of other nutrient elements
0.563 0.437 0.000
J20-J22 Other acute lower respiratory infections
0.563 0.437 0.000
F80 Specific developmental disorders of speech and language
0.561 0.439 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.561 0.439 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.560 0.439 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.560 0.439 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.560 0.439 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.560 0.439 0.000
M43.12 Spondylolisthesis (Cervical region)
0.560 0.439 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.560 0.439 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.560 0.439 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.558 0.442 0.000
M34.9 Systemic sclerosis, unspecified
0.558 0.442 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.557 0.443 0.000
F09 Unspecified organic or symptomatic mental disorder
0.556 0.443 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.556 0.443 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.555 0.445 0.000
G20 Parkinson's disease
0.554 0.446 0.000
X60-X84 Intentional self-harm
0.553 0.447 0.000
Q61.9 Cystic kidney disease, unspecified
0.552 0.448 0.000
Q61.8 Other cystic kidney diseases
0.552 0.448 0.000
Q61.5 Medullary cystic kidney
0.552 0.448 0.000
Q61.4 Renal dysplasia
0.552 0.448 0.000
Q61.1 Polycystic kidney, infantile type
0.552 0.448 0.000
J38.1 Polyp of vocal cord and larynx
0.551 0.449 0.000
M43.0 Spondylolysis
0.551 0.449 0.000
Q78 Other osteochondrodysplasias
0.550 0.450 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.550 0.450 0.000
E15 Nondiabetic hypoglycaemic coma
0.549 0.450 0.000
W75-W84 Other accidental threats to breathing
0.549 0.451 0.000
J14 Pneumonia due to Haemophilus influenzae
0.548 0.452 0.000
G47 Sleep disorders
0.547 0.453 0.000
M84 Disorders of continuity of bone
0.547 0.453 0.000
J69.0 Pneumonitis due to food and vomit
0.547 0.453 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.546 0.453 0.000
E83.8 Other disorders of mineral metabolism
0.546 0.453 0.000
E83.2 Disorders of zinc metabolism
0.546 0.453 0.000
E83.0 Disorders of copper metabolism
0.546 0.453 0.000
J38.6 Stenosis of larynx
0.546 0.454 0.000
G72 Other myopathies
0.545 0.454 0.000
J12 Viral pneumonia, not elsewhere classified
0.545 0.455 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.544 0.456 0.000
O04.7 Complete or unspecified, complicated by embolism
0.544 0.456 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.544 0.456 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.544 0.456 0.000
O04.3 Incomplete, with other and unspecified complications
0.544 0.456 0.000
O04.2 Incomplete, complicated by embolism
0.544 0.456 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.544 0.456 0.000
E80.4 Gilbert's syndrome
0.544 0.456 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.544 0.456 0.000
E63 Other nutritional deficiencies
0.544 0.456 0.000
E56 Other vitamin deficiencies
0.544 0.456 0.000
E51 Thiamine deficiency
0.544 0.456 0.000
E50 Vitamin A deficiency
0.544 0.456 0.000
E60 Dietary zinc deficiency
0.544 0.456 0.000
E59 Dietary selenium deficiency
0.544 0.456 0.000
E58 Dietary calcium deficiency
0.544 0.456 0.000
E54 Ascorbic acid deficiency
0.544 0.456 0.000
E52 Niacin deficiency [pellagra]
0.544 0.456 0.000
M87 Osteonecrosis
0.544 0.456 0.000
V40-V49 Car occupant injured in transport accident
0.544 0.456 0.000
M54.1 Radiculopathy
0.543 0.457 0.000
M89.6 Osteopathy after poliomyelitis
0.543 0.457 0.000
M89.5 Osteolysis
0.543 0.457 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.543 0.457 0.000
M89.3 Hypertrophy of bone
0.543 0.457 0.000
M89.2 Other disorders of bone development and growth
0.543 0.457 0.000
M89.1 Epiphyseal arrest
0.543 0.457 0.000
Q43 Other congenital malformations of intestine
0.543 0.457 0.000
M91-M94 Chondropathies
0.541 0.458 0.000
M45 Ankylosing spondylitis
0.542 0.458 0.000
M48.02 Spinal stenosis (Cervical region)
0.540 0.460 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.540 0.460 0.000
J38.5 Laryngeal spasm
0.537 0.463 0.000
O00.9 Ectopic pregnancy, unspecified
0.537 0.463 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.536 0.464 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.535 0.465 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.533 0.467 0.000
M82 Osteoporosis in diseases classified elsewhere
0.532 0.468 0.000
F23 Acute and transient psychotic disorders
0.532 0.468 0.000
G40 Epilepsy
0.532 0.468 0.000
M53.9 Dorsopathy, unspecified
0.532 0.468 0.000
M53.8 Other specified dorsopathies
0.532 0.468 0.000
M53.2 Spinal instabilities
0.532 0.468 0.000
M53.1 Cervicobrachial syndrome
0.532 0.468 0.000
M53.0 Cervicocranial syndrome
0.532 0.468 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.532 0.468 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.531 0.468 0.000
V18.0 Driver injured in nontraffic accident
0.531 0.469 0.000
E22 Hyperfunction of pituitary gland
0.530 0.470 0.000
F20.0 Paranoid schizophrenia
0.530 0.470 0.000
M34.1 CR(E)ST syndrome
0.529 0.471 0.000
M54.4 Lumbago with sciatica
0.529 0.471 0.000
E11.8 With unspecified complications
0.527 0.473 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.527 0.473 0.000
J17.2 Pneumonia in mycoses
0.527 0.473 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.525 0.475 0.000
M40.2 Other and unspecified kyphosis
0.525 0.475 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.525 0.475 0.000
J39.8 Other specified diseases of upper respiratory tract
0.525 0.475 0.000
M34.8 Other forms of systemic sclerosis
0.524 0.476 0.000
M48.9 Spondylopathy, unspecified
0.523 0.477 0.000
M48.8 Other specified spondylopathies
0.523 0.477 0.000
M48.4 Fatigue fracture of vertebra
0.523 0.477 0.000
M48.3 Traumatic spondylopathy
0.523 0.477 0.000
M48.2 Kissing spine
0.523 0.477 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.523 0.477 0.000
M54.55 Low back pain (Thoracolumbar region)
0.522 0.477 0.000
M54.54 Low back pain-Thoracic
0.522 0.477 0.000
M54.53 Low back pain-Cervicothoracic
0.522 0.477 0.000
M54.52 Low back pain-Cervical
0.522 0.477 0.000
M54.51 Low back pain-Occipit-atl-axl
0.522 0.477 0.000
J15.2 Pneumonia due to staphylococcus
0.522 0.478 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.521 0.479 0.000
E11.7 With multiple complications
0.520 0.480 0.000
E40-E46 Malnutrition
0.520 0.480 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.520 0.480 0.000
Q63.0 Accessory kidney
0.519 0.481 0.000
X20-X29 Contact with venomous animals and plants
0.518 0.482 0.000
E10.8 With unspecified complications
0.518 0.482 0.000
E11.0 With coma
0.518 0.482 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.518 0.482 0.000
J09 Influenza due to certain identified influenza virus
0.518 0.482 0.000
M46.4 Discitis, unspecified
0.517 0.482 0.000
G03 Meningitis due to other and unspecified causes
0.517 0.483 0.000
U88 Agent resistant to multiple antibiotics
0.517 0.483 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.516 0.484 0.000
Q76 Congenital malformations of spine and bony thorax
0.515 0.484 0.000
E10.6 With other specified complications
0.515 0.485 0.000
E26 Hyperaldosteronism
0.515 0.485 0.000
F30-F39 Mood [affective] disorders
0.515 0.485 0.000
G90 Disorders of autonomic nervous system
0.515 0.485 0.000
G63.2 Diabetic polyneuropathy
0.514 0.486 0.000
Y00-Y09 Assault
0.512 0.487 0.000
M66 Spontaneous rupture of synovium and tendon
0.512 0.488 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.512 0.488 0.000
Y35-Y36 Legal intervention and operations of war
0.512 0.488 0.000
Y10-Y34 Event of undetermined intent
0.512 0.488 0.000
X85-X99 Assault
0.512 0.488 0.000
X30-X39 Exposure to forces of nature
0.512 0.488 0.000
X10-X19 Contact with heat and hot substances
0.512 0.488 0.000
X00-X09 Exposure to smoke, fire and flames
0.512 0.488 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.512 0.488 0.000
W65-W74 Accidental drowning and submersion
0.512 0.488 0.000
V98-V99 Other and unspecified transport accidents
0.512 0.488 0.000
V95-V97 Air and space transport accidents
0.512 0.488 0.000
V90-V94 Water transport accidents
0.512 0.488 0.000
V70-V79 Bus occupant injured in transport accident
0.512 0.488 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.512 0.488 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.512 0.488 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.512 0.488 0.000
V01-V09 Pedestrian injured in transport accident
0.512 0.488 0.000
M24.6 Ankylosis of joint
0.511 0.489 0.000
M67 Other disorders of synovium and tendon
0.511 0.489 0.000
M24.5 Contracture of joint
0.511 0.489 0.000
Q87.4 Marfan's syndrome
0.511 0.489 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.510 0.490 0.000
M48.04 Spinal stenosis (Thoracic region)
0.510 0.490 0.000
O86 Other puerperal infections
0.510 0.490 0.000
G64 Other disorders of peripheral nervous system
0.509 0.491 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.509 0.491 0.000
Q75 Other congenital malformations of skull and face bones
0.509 0.491 0.000
Q74 Other congenital malformations of limb(s)
0.509 0.491 0.000
Q73 Reduction defects of unspecified limb
0.509 0.491 0.000
Q72 Reduction defects of lower limb
0.509 0.491 0.000
Q71 Reduction defects of upper limb
0.509 0.491 0.000
Q70 Syndactyly
0.509 0.491 0.000
Q69 Polydactyly
0.509 0.491 0.000
Q68 Other congenital musculoskeletal deformities
0.509 0.491 0.000
W55 Bitten or struck by other mammals
0.509 0.491 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.509 0.491 0.000
E78.4 Other hyperlipidaemia
0.509 0.491 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.509 0.491 0.000
J15.9 Bacterial pneumonia, unspecified
0.507 0.493 0.000
J15.8 Other bacterial pneumonia
0.507 0.493 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.507 0.493 0.000
J15.5 Pneumonia due to Escherichia coli
0.507 0.493 0.000
J15.3 Pneumonia due to streptococcus, group B
0.507 0.493 0.000
E16.1 Other hypoglycaemia
0.507 0.493 0.000
M54.89 Other dorsalgia (Site unspecified)
0.506 0.494 0.000
M60.0 Infective myositis
0.505 0.494 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.505 0.495 0.000
E80.5 Crigler-Najjar syndrome
0.505 0.495 0.000
E80.3 Defects of catalase and peroxydase
0.505 0.495 0.000
E80.2 Other porphyria
0.505 0.495 0.000
E80.1 Porphyria cutanea tarda
0.505 0.495 0.000
E80.0 Hereditary erythropoietic porphyria
0.505 0.495 0.000
F25 Schizoaffective disorders
0.505 0.495 0.000
Q66 Congenital deformities of feet
0.505 0.495 0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.504 0.496 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.504 0.496 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.504 0.496 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.504 0.496 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.504 0.496 0.000
M50.2 Other cervical disk displacement
0.504 0.496 0.000
M88 Paget's disease of bone [osteitis deformans]
0.503 0.497 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.503 0.497 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.502 0.498 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.502 0.498 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.502 0.498 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.502 0.498 0.000
J37 Chronic laryngitis and laryngotracheitis
0.500 0.500 0.000
G83.9 Paralytic syndrome, unspecified
0.500 0.500 0.000
E11.1 With ketoacidosis
0.499 0.500 0.000
E23 Hypofunction and other disorders of pituitary gland
0.499 0.501 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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