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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62231188
log Bayes Factor = 17.7829
Chromosome 22   position 24,984,215  (GRCh37) Explore rs62231188 on Ensembl!
Variant rs62231188 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
K29 Gastritis and duodenitis
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
R07 Pain in throat and chest
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
Chapter XIV Diseases of the genitourinary system
0.992 0.008 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.988 0.012 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
K31 Other diseases of stomach and duodenum
0.982 0.018 0.000
K31.7 Polyp of stomach and duodenum
0.970 0.030 0.000
R50-R69 General symptoms and signs
0.967 0.033 0.000
J09-J18 Influenza and pneumonia
0.964 0.036 0.000
Z36 Antenatal screening
0.957 0.043 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
R07.2 Precordial pain
0.956 0.044 0.000
S09 Other and unspecified injuries of head
0.952 0.048 0.000
Chapter II Neoplasms
0.946 0.054 0.000
K29.6 Other gastritis
0.944 0.056 0.000
N20-N23 Urolithiasis
0.943 0.057 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.942 0.058 0.000
J30-J39 Other diseases of upper respiratory tract
0.938 0.062 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.937 0.063 0.000
J18 Pneumonia, organism unspecified
0.935 0.065 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.933 0.067 0.000
Chapter IX Diseases of the circulatory system
0.931 0.069 0.000
S09.9 Unspecified injury of head
0.931 0.069 0.000
N17-N19 Renal failure
0.929 0.071 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.925 0.075 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.925 0.075 0.000
R07.4 Chest pain, unspecified
0.924 0.076 0.000
K22 Other diseases of oesophagus
0.924 0.076 0.000
C50-C50 Malignant neoplasm of breast
0.923 0.077 0.000
K29.8 Duodenitis
0.922 0.078 0.000
I95 Hypotension
0.920 0.080 0.000
R00 Abnormalities of heart beat
0.920 0.080 0.000
R07.3 Other chest pain
0.919 0.081 0.000
I95.9 Hypotension, unspecified
0.918 0.082 0.000
Z36.8 Other antenatal screening
0.912 0.088 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.908 0.092 0.000
J00-J06 Acute upper respiratory infections
0.908 0.092 0.000
C50 Malignant neoplasm of breast
0.906 0.094 0.000
R56 Convulsions, not elsewhere classified
0.903 0.097 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.901 0.099 0.000
K29.7 Gastritis, unspecified
0.899 0.101 0.000
Z37 Outcome of delivery
0.896 0.104 0.000
F10.3 Withdrawal state
0.895 0.105 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.894 0.106 0.000
R59 Enlarged lymph nodes
0.887 0.113 0.000
N19 Unspecified renal failure
0.884 0.116 0.000
N23 Unspecified renal colic
0.881 0.119 0.000
O60-O75 Complications of labour and delivery
0.880 0.120 0.000
R47-R49 Symptoms and signs involving speech and voice
0.878 0.122 0.000
R63 Symptoms and signs concerning food and fluid intake
0.871 0.129 0.000
K29.5 Chronic gastritis, unspecified
0.868 0.132 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.867 0.133 0.000
J18.1 Lobar pneumonia, unspecified
0.864 0.136 0.000
Chapter VIII Diseases of the ear and mastoid process
0.863 0.137 0.000
C50.4 Upper-outer quadrant of breast
0.862 0.138 0.000
N87 Dysplasia of cervix uteri
0.859 0.141 0.000
R11 Nausea and vomiting
0.858 0.142 0.000
J18.9 Pneumonia, unspecified
0.858 0.142 0.000
S01 Open wound of head
0.858 0.142 0.000
K70-K77 Diseases of liver
0.858 0.142 0.000
R56.8 Other and unspecified convulsions
0.857 0.143 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.857 0.143 0.000
S50-S59 Injuries to the elbow and forearm
0.856 0.144 0.000
K25 Gastric ulcer
0.856 0.144 0.000
M20-M25 Other joint disorders
0.856 0.144 0.000
A30-A49 Other bacterial diseases
0.855 0.145 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.849 0.151 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.840 0.160 0.000
K65-K67 Diseases of peritoneum
0.840 0.160 0.000
N95 Menopausal and other perimenopausal disorders
0.839 0.161 0.000
K29.2 Alcoholic gastritis
0.838 0.162 0.000
N99-N99 Other disorders of the genitourinary system
0.835 0.165 0.000
Chapter VI Diseases of the nervous system
0.833 0.167 0.000
C79 Secondary malignant neoplasm of other sites
0.832 0.168 0.000
F10.0 Acute intoxication
0.827 0.173 0.000
R53 Malaise and fatigue
0.827 0.173 0.000
Z30 Contraceptive management
0.826 0.174 0.000
R26 Abnormalities of gait and mobility
0.826 0.174 0.000
J40-J47 Chronic lower respiratory diseases
0.825 0.175 0.000
S60-S69 Injuries to the wrist and hand
0.823 0.177 0.000
S20-S29 Injuries to the thorax
0.823 0.177 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.822 0.178 0.000
O80-O84 Delivery
0.821 0.179 0.000
K22.2 Oesophageal obstruction
0.819 0.181 0.000
O42 Premature rupture of membranes
0.818 0.182 0.000
R15 Faecal incontinence
0.816 0.184 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.816 0.184 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.815 0.185 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.814 0.186 0.000
R00.0 Tachycardia, unspecified
0.811 0.189 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.810 0.190 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.810 0.190 0.000
R50 Fever of unknown origin
0.808 0.191 0.000
F10.1 Harmful use
0.808 0.192 0.000
J95-J99 Other diseases of the respiratory system
0.807 0.193 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.805 0.195 0.000
J32 Chronic sinusitis
0.805 0.195 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
O36 Maternal care for other known or suspected foetal problems
0.805 0.195 0.000
N17 Acute renal failure
0.804 0.196 0.000
K30 Dyspepsia
0.804 0.196 0.000
J00 Acute nasopharyngitis [common cold]
0.804 0.196 0.000
R04 Haemorrhage from respiratory passages
0.803 0.197 0.000
I30-I52 Other forms of heart disease
0.802 0.198 0.000
R59.0 Localised enlarged lymph nodes
0.801 0.199 0.000
N81 Female genital prolapse
0.800 0.200 0.000
N20 Calculus of kidney and ureter
0.798 0.202 0.000
N60-N64 Disorders of breast
0.798 0.202 0.000
B95-B98 Bacterial, viral and other infectious agents
0.797 0.203 0.000
R02 Gangrene, not elsewhere classified
0.795 0.205 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
N87.0 Mild cervical dysplasia
0.794 0.206 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
A41 Other septicaemia
0.793 0.207 0.000
B25-B34 Other viral diseases
0.788 0.212 0.000
K31.8 Other specified diseases of stomach and duodenum
0.785 0.215 0.000
K29.0 Acute haemorrhagic gastritis
0.785 0.215 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.785 0.215 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.783 0.217 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.782 0.218 0.000
F41 Other anxiety disorders
0.781 0.219 0.000
M50-M54 Other dorsopathies
0.780 0.220 0.000
M35 Other systemic involvement of connective tissue
0.780 0.220 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.778 0.222 0.000
K29.3 Chronic superficial gastritis
0.777 0.223 0.000
H90-H95 Other disorders of ear
0.776 0.224 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.776 0.224 0.000
T66-T78 Other and unspecified effects of external causes
0.773 0.227 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.772 0.228 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.772 0.228 0.000
J34 Other disorders of nose and nasal sinuses
0.771 0.229 0.000
Z35 Supervision of high-risk pregnancy
0.769 0.231 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.767 0.233 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.767 0.233 0.000
K22.1 Ulcer of oesophagus
0.765 0.235 0.000
B35-B49 Mycoses
0.764 0.236 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.763 0.237 0.000
O48 Prolonged pregnancy
0.760 0.240 0.000
Z34 Supervision of normal pregnancy
0.760 0.240 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.759 0.241 0.000
Z02 Examination and encounter for administrative purposes
0.757 0.243 0.000
Z37.0 Single live birth
0.756 0.244 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.755 0.245 0.000
J60-J70 Lung diseases due to external agents
0.754 0.246 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
S52 Fracture of forearm
0.754 0.246 0.000
K35-K38 Diseases of appendix
0.753 0.247 0.000
K26 Duodenal ulcer
0.753 0.247 0.000
R60 Oedema, not elsewhere classified
0.753 0.247 0.000
T79-T79 Certain early complications of trauma
0.753 0.247 0.000
R07.1 Chest pain on breathing
0.751 0.249 0.000
Z37.1 Single stillbirth
0.749 0.251 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.749 0.251 0.000
N81.2 Incomplete uterovaginal prolapse
0.748 0.252 0.000
N88 Other noninflammatory disorders of cervix uteri
0.745 0.255 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.745 0.255 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.745 0.255 0.000
I45 Other conduction disorders
0.742 0.258 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.742 0.258 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.741 0.259 0.000
R00.1 Bradycardia, unspecified
0.741 0.259 0.000
J90-J94 Other diseases of pleura
0.741 0.259 0.000
Chapter XX External causes of morbidity and mortality
0.741 0.259 0.000
J02 Acute pharyngitis
0.740 0.260 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.740 0.260 0.000
M35.3 Polymyalgia rheumatica
0.740 0.260 0.000
R25 Abnormal involuntary movements
0.739 0.261 0.000
S06 Intracranial injury
0.737 0.263 0.000
S01.0 Open wound of scalp
0.736 0.264 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.736 0.264 0.000
C50.3 Lower-inner quadrant of breast
0.736 0.264 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.735 0.265 0.000
C50.2 Upper-inner quadrant of breast
0.734 0.266 0.000
N25-N29 Other disorders of kidney and ureter
0.733 0.267 0.000
I60-I69 Cerebrovascular diseases
0.733 0.267 0.000
C50.9 Breast, unspecified
0.731 0.269 0.000
R49 Voice disturbances
0.731 0.269 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.731 0.269 0.000
K22.7 Barrett's oesophagus
0.730 0.270 0.000
R47 Speech disturbances, not elsewhere classified
0.730 0.270 0.000
N92 Excessive, frequent and irregular menstruation
0.730 0.270 0.000
E70-E90 Metabolic disorders
0.729 0.271 0.000
G40-G47 Episodic and paroxysmal disorders
0.728 0.272 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.728 0.272 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.727 0.272 0.000
M25 Other joint disorders, not elsewhere classified
0.727 0.273 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.726 0.274 0.000
R54 Senility
0.726 0.274 0.000
J32.9 Chronic sinusitis, unspecified
0.726 0.274 0.000
A41.9 Septicaemia, unspecified
0.726 0.274 0.000
S70-S79 Injuries to the hip and thigh
0.725 0.275 0.000
O47 False labour
0.725 0.275 0.000
R00.2 Palpitations
0.725 0.275 0.000
R63.4 Abnormal weight loss
0.724 0.276 0.000
C34 Malignant neoplasm of bronchus and lung
0.722 0.278 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.722 0.278 0.000
N95.2 Postmenopausal atrophic vaginitis
0.722 0.278 0.000
N00-N08 Glomerular diseases
0.722 0.278 0.000
K75 Other inflammatory liver diseases
0.721 0.279 0.000
K65 Peritonitis
0.721 0.279 0.000
M80-M85 Disorders of bone density and structure
0.721 0.279 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.720 0.280 0.000
Z02.8 Other examinations for administrative purposes
0.719 0.281 0.000
N20.0 Calculus of kidney
0.719 0.281 0.000
Z39 Postpartum care and examination
0.718 0.282 0.000
M20 Acquired deformities of fingers and toes
0.718 0.282 0.000
S00 Superficial injury of head
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K27 Peptic ulcer, site unspecified
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z36.9 Antenatal screening, unspecified
0.717 0.283 0.000
K29.9 Gastroduodenitis, unspecified
0.716 0.284 0.000
N17.9 Acute renal failure, unspecified
0.715 0.285 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.714 0.286 0.000
K29.4 Chronic atrophic gastritis
0.713 0.287 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.711 0.288 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.710 0.290 0.000
O70 Perineal laceration during delivery
0.710 0.290 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.710 0.290 0.000
O36.8 Maternal care for other specified foetal problems
0.710 0.290 0.000
M54 Dorsalgia
0.709 0.291 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.709 0.291 0.000
Z38 Liveborn infants according to place of birth
0.708 0.292 0.000
Z32 Pregnancy examination and test
0.708 0.292 0.000
Z31 Procreative management
0.708 0.292 0.000
Z33 Pregnant state, incidental
0.708 0.292 0.000
F99-F99 Unspecified mental disorder
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.292 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
F60-F69 Disorders of adult personality and behaviour
0.708 0.292 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.706 0.294 0.000
R07.0 Pain in throat
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
S02 Fracture of skull and facial bones
0.705 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.705 0.295 0.000
K31.6 Fistula of stomach and duodenum
0.704 0.296 0.000
K31.5 Obstruction of duodenum
0.704 0.296 0.000
K31.4 Gastric diverticulum
0.704 0.296 0.000
K31.3 Pylorospasm, not elsewhere classified
0.704 0.296 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.704 0.296 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.704 0.296 0.000
K31.0 Acute dilatation of stomach
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
N81.6 Rectocele
0.704 0.296 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.703 0.296 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.703 0.297 0.000
R50.9 Fever, unspecified
0.703 0.297 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.702 0.298 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.702 0.298 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.701 0.299 0.000
O63 Long labour
0.700 0.300 0.000
R63.1 Polydipsia
0.700 0.300 0.000
R27 Other lack of coordination
0.698 0.302 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.698 0.302 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.697 0.303 0.000
N86 Erosion and ectropion of cervix uteri
0.696 0.304 0.000
K22.4 Dyskinesia of oesophagus
0.696 0.304 0.000
O00-O08 Pregnancy with abortive outcome
0.696 0.304 0.000
R13 Dysphagia
0.696 0.304 0.000
J84 Other interstitial pulmonary diseases
0.695 0.305 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.694 0.306 0.000
R68 Other general symptoms and signs
0.694 0.306 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.694 0.306 0.000
R62 Lack of expected normal physiological development
0.694 0.306 0.000
R57 Shock, not elsewhere classified
0.694 0.306 0.000
R64 Cachexia
0.694 0.306 0.000
R58 Haemorrhage, not elsewhere classified
0.694 0.306 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.693 0.307 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.692 0.308 0.000
J17 Pneumonia in diseases classified elsewhere
0.691 0.309 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.691 0.309 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.691 0.309 0.000
J12 Viral pneumonia, not elsewhere classified
0.691 0.309 0.000
J11 Influenza, virus not identified
0.691 0.309 0.000
J10 Influenza due to identified influenza virus
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.691 0.309 0.000
J09 Influenza due to certain identified influenza virus
0.691 0.309 0.000
R63.0 Anorexia
0.690 0.310 0.000
Z37.2 Twins, both liveborn
0.689 0.311 0.000
R04.0 Epistaxis
0.689 0.311 0.000
R59.1 Generalised enlarged lymph nodes
0.687 0.313 0.000
J03 Acute tonsillitis
0.687 0.313 0.000
R17 Unspecified jaundice
0.686 0.313 0.000
Z36.5 Antenatal screening for isoimmunisation
0.686 0.314 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.686 0.314 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.686 0.314 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.686 0.314 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.685 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.685 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.685 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.685 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.685 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.685 0.315 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.685 0.315 0.000
J33 Nasal polyp
0.685 0.315 0.000
J30 Vasomotor and allergic rhinitis
0.684 0.316 0.000
S09.8 Other specified injuries of head
0.683 0.317 0.000
S09.7 Multiple injuries of head
0.683 0.317 0.000
S09.2 Traumatic rupture of ear drum
0.683 0.317 0.000
S09.1 Injury of muscle and tendon of head
0.683 0.317 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.683 0.317 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.683 0.317 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.682 0.318 0.000
M91-M94 Chondropathies
0.682 0.318 0.000
I45.1 Other and unspecified right bundle-branch block
0.682 0.318 0.000
I50 Heart failure
0.681 0.319 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.680 0.320 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.679 0.321 0.000
N60 Benign mammary dysplasia
0.679 0.321 0.000
J40 Bronchitis, not specified as acute or chronic
0.679 0.321 0.000
J34.2 Deviated nasal septum
0.679 0.321 0.000
Z30.2 Sterilisation
0.678 0.322 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.678 0.322 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.678 0.322 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.678 0.322 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.678 0.322 0.000
K70 Alcoholic liver disease
0.678 0.322 0.000
C50.8 Overlapping lesion of breast
0.677 0.323 0.000
B34 Viral infection of unspecified site
0.677 0.323 0.000
F10.2 Dependence syndrome
0.677 0.323 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.676 0.324 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
F10.9 Unspecified mental and behavioural disorder
0.675 0.325 0.000
F10.8 Other mental and behavioural disorders
0.675 0.325 0.000
F10.7 Residual and late-onset psychotic disorder
0.675 0.325 0.000
F10.6 Amnesic syndrome
0.675 0.325 0.000
F10.5 Psychotic disorder
0.675 0.325 0.000
F10.4 Withdrawal state with delirium
0.675 0.325 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.675 0.325 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.675 0.325 0.000
Z30.3 Menstrual extraction
0.673 0.327 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.673 0.327 0.000
J37 Chronic laryngitis and laryngotracheitis
0.672 0.328 0.000
J35 Chronic diseases of tonsils and adenoids
0.672 0.328 0.000
M21 Other acquired deformities of limbs
0.672 0.328 0.000
R59.9 Enlarged lymph nodes, unspecified
0.672 0.328 0.000
O45 Premature separation of placenta [abruptio placentae]
0.672 0.328 0.000
O44 Placenta praevia
0.672 0.328 0.000
O43 Placental disorders
0.672 0.328 0.000
O41 Other disorders of amniotic fluid and membranes
0.672 0.328 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.672 0.328 0.000
O33 Maternal care for known or suspected disproportion
0.672 0.328 0.000
O31 Complications specific to multiple gestation
0.672 0.328 0.000
O30 Multiple gestation
0.672 0.328 0.000
O40 Polyhydramnios
0.672 0.328 0.000
S01.9 Open wound of head, part unspecified
0.671 0.328 0.000
J18.8 Other pneumonia, organism unspecified
0.670 0.329 0.000
J18.2 Hypostatic pneumonia, unspecified
0.670 0.329 0.000
J18.0 Bronchopneumonia, unspecified
0.670 0.329 0.000
O42.9 Premature rupture of membranes, unspecified
0.670 0.330 0.000
I31 Other diseases of pericardium
0.669 0.331 0.000
N98 Complications associated with artificial fertilisation
0.669 0.331 0.000
N91 Absent, scanty and rare menstruation
0.669 0.331 0.000
N82 Fistulae involving female genital tract
0.669 0.331 0.000
N96 Habitual aborter
0.669 0.331 0.000
F41.2 Mixed anxiety and depressive disorder
0.669 0.331 0.000
F41.9 Anxiety disorder, unspecified
0.669 0.331 0.000
O73 Retained placenta and membranes, without haemorrhage
0.668 0.331 0.000
N21 Calculus of lower urinary tract
0.668 0.332 0.000
I00-I02 Acute rheumatic fever
0.668 0.332 0.000
K22.9 Disease of oesophagus, unspecified
0.668 0.332 0.000
S52.5 Fracture of lower end of radius
0.667 0.333 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.666 0.334 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.664 0.336 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.663 0.337 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.663 0.337 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.663 0.337 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.663 0.337 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.663 0.337 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.663 0.337 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.663 0.337 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.663 0.337 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.663 0.337 0.000
T36 Poisoning by systemic antibiotics
0.663 0.337 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.663 0.337 0.000
I99 Other and unspecified disorders of circulatory system
0.663 0.337 0.000
K22.5 Diverticulum of oesophagus, acquired
0.662 0.337 0.000
K22.3 Perforation of oesophagus
0.662 0.337 0.000
K22.0 Achalasia of cardia
0.662 0.337 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.662 0.338 0.000
J39 Other diseases of upper respiratory tract
0.661 0.339 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.661 0.339 0.000
N87.1 Moderate cervical dysplasia
0.661 0.339 0.000
N97 Female infertility
0.660 0.340 0.000
I95.8 Other hypotension
0.660 0.340 0.000
I95.2 Hypotension due to drugs
0.660 0.340 0.000
I95.0 Idiopathic hypotension
0.660 0.340 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.659 0.340 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
R52 Pain, not elsewhere classified
0.659 0.341 0.000
O80 Single spontaneous delivery
0.658 0.342 0.000
O82 Single delivery by Caesarean section
0.657 0.343 0.000
O72 Postpartum haemorrhage
0.656 0.344 0.000
S61 Open wound of wrist and hand
0.655 0.345 0.000
M45-M49 Spondylopathies
0.655 0.345 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.655 0.345 0.000
C50.1 Central portion of breast
0.655 0.345 0.000
N10-N16 Renal tubulo-interstitial diseases
0.654 0.346 0.000
M31 Other necrotising vasculopathies
0.654 0.346 0.000
R05 Cough
0.653 0.347 0.000
J31.0 Chronic rhinitis
0.653 0.347 0.000
J47 Bronchiectasis
0.653 0.347 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.651 0.349 0.000
J04 Acute laryngitis and tracheitis
0.651 0.349 0.000
J01 Acute sinusitis
0.651 0.349 0.000
I95.1 Orthostatic hypotension
0.651 0.349 0.000
C50.6 Axillary tail of breast
0.650 0.350 0.000
C50.5 Lower-outer quadrant of breast
0.650 0.350 0.000
C50.0 Nipple and areola
0.650 0.350 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.650 0.350 0.000
Z01.8 Other specified special examinations
0.650 0.350 0.000
J36 Peritonsillar abscess
0.649 0.350 0.000
N93 Other abnormal uterine and vaginal bleeding
0.648 0.352 0.000
R56.0 Febrile convulsions
0.647 0.352 0.000
K25.7 Chronic without haemorrhage or perforation
0.647 0.353 0.000
C64-C68 Malignant neoplasms of urinary tract
0.647 0.353 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.646 0.354 0.000
Z72 Problems related to lifestyle
0.646 0.354 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.646 0.354 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.646 0.354 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.644 0.356 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.642 0.358 0.000
Z37.9 Outcome of delivery unspecified
0.642 0.358 0.000
Z37.7 Other multiple births, all stillborn
0.642 0.358 0.000
Z37.6 Other multiple births, some liveborn
0.642 0.358 0.000
Z37.5 Other multiple births, all liveborn
0.642 0.358 0.000
Z37.4 Twins, both stillborn
0.642 0.358 0.000
Z37.3 Twins, one liveborn and one stillborn
0.642 0.358 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.642 0.358 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.641 0.359 0.000
M86-M90 Other osteopathies
0.641 0.359 0.000
M60-M63 Disorders of muscles
0.641 0.359 0.000
M00-M03 Infectious arthropathies
0.641 0.359 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.641 0.359 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.641 0.359 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.641 0.359 0.000
M24 Other specific joint derangements
0.640 0.360 0.000
S01.5 Open wound of lip and oral cavity
0.640 0.360 0.000
F20 Schizophrenia
0.640 0.360 0.000
S20 Superficial injury of thorax
0.639 0.361 0.000
N95.0 Postmenopausal bleeding
0.638 0.362 0.000
J43 Emphysema
0.638 0.362 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.637 0.363 0.000
K65.0 Acute peritonitis
0.636 0.363 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.636 0.364 0.000
S80-S89 Injuries to the knee and lower leg
0.635 0.364 0.000
B37 Candidiasis
0.635 0.365 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.635 0.365 0.000
J98 Other respiratory disorders
0.635 0.365 0.000
M20.4 Other hammer toe(s) (acquired)
0.635 0.365 0.000
C34.9 Bronchus or lung, unspecified
0.634 0.366 0.000
K90-K93 Other diseases of the digestive system
0.633 0.367 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.633 0.367 0.000
H90 Conductive and sensorineural hearing loss
0.633 0.367 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.632 0.368 0.000
J34.3 Hypertrophy of nasal turbinates
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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