TreeWAS – Variant ID: rs62242686

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000	0.000
M20-M25 Other joint disorders	0.999	0.001	0.000
M15-M19 Arthrosis	0.998	0.002	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.998	0.002	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.996	0.004	0.000
M23 Internal derangement of knee	0.994	0.006	0.000
Chapter XXI Factors influencing health status and contact with health services	0.993	0.007	0.000
Chapter VII Diseases of the eye and adnexa	0.993	0.007	0.000
Z95.1 Presence of aortocoronary bypass graft	0.991	0.009	0.000
I25.2 Old myocardial infarction	0.990	0.010	0.000
I30-I52 Other forms of heart disease	0.988	0.012	0.000
M25 Other joint disorders, not elsewhere classified	0.984	0.016	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.982	0.018	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.982	0.018	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.980	0.020	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.979	0.021	0.000
M17 Gonarthrosis [arthrosis of knee]	0.978	0.022	0.000
M19 Other arthrosis	0.976	0.024	0.000
M17.9 Gonarthrosis, unspecified	0.972	0.028	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.970	0.030	0.000
Z88.6 Personal history of allergy to analgesic agent	0.968	0.032	0.000
Z95.0 Presence of cardiac pacemaker	0.967	0.033	0.000
M19.9 Arthrosis, unspecified	0.961	0.039	0.000
Z96 Presence of other functional implants	0.960	0.040	0.000
H25-H28 Disorders of lens	0.960	0.040	0.000
I50 Heart failure	0.958	0.042	0.000
I20 Angina pectoris	0.956	0.044	0.000
I25.1 Atherosclerotic heart disease	0.951	0.049	0.000
H25 Senile cataract	0.945	0.055	0.000
Chapter VIII Diseases of the ear and mastoid process	0.945	0.055	0.000
H25.8 Other senile cataract	0.940	0.060	0.000
M80-M85 Disorders of bone density and structure	0.937	0.063	0.000
M50-M54 Other dorsopathies	0.935	0.065	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.935	0.065	0.000
I44 Atrioventricular and left bundle-branch block	0.927	0.073	0.000
I50.1 Left ventricular failure	0.926	0.074	0.000
I20.9 Angina pectoris, unspecified	0.922	0.078	0.000
M25.5 Pain in joint	0.922	0.078	0.000
S80-S89 Injuries to the knee and lower leg	0.917	0.083	0.000
Z97 Presence of other devices	0.916	0.084	0.000
Z96.8 Presence of other specified functional implants	0.913	0.087	0.000
Chapter I Certain infectious and parasitic diseases	0.904	0.096	0.000
I21 Acute myocardial infarction	0.904	0.096	0.000
H65-H75 Diseases of middle ear and mastoid	0.902	0.098	0.000
M23.3 Other meniscus derangements	0.901	0.099	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.900	0.100	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.897	0.103	0.000
Z96.6 Presence of orthopaedic joint implants	0.892	0.108	0.000
M65-M68 Disorders of synovium and tendon	0.892	0.108	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.890	0.110	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.885	0.115	0.000
H53-H54 Visual disturbances and blindness	0.882	0.118	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.879	0.121	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.877	0.123	0.000
M51 Other intervertebral disk disorders	0.876	0.124	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.872	0.128	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.865	0.135	0.000
M25.4 Effusion of joint	0.864	0.136	0.000
M23.8 Other internal derangements of knee	0.864	0.136	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.863	0.137	0.000
H55-H59 Other disorders of eye and adnexa	0.860	0.140	0.000
I21.4 Acute subendocardial myocardial infarction	0.857	0.143	0.000
I21.9 Acute myocardial infarction, unspecified	0.853	0.147	0.000
I45 Other conduction disorders	0.853	0.147	0.000
B95-B98 Bacterial, viral and other infectious agents	0.852	0.148	0.000
H65 Nonsuppurative otitis media	0.846	0.154	0.000
M25.51 Pain in joint (Shoulder region)	0.846	0.154	0.000
M18 Arthrosis of first carpometacarpal joint	0.846	0.154	0.000
D50-D53 Nutritional anaemias	0.845	0.155	0.000
I44.0 Atrioventricular block, first degree	0.841	0.158	0.000
I24 Other acute ischaemic heart diseases	0.837	0.163	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.836	0.164	0.000
I20.8 Other forms of angina pectoris	0.835	0.165	0.000
I38 Endocarditis, valve unspecified	0.835	0.165	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.831	0.169	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.830	0.169	0.000
M25.7 Osteophyte	0.828	0.172	0.000
Z95.3 Presence of xenogenic heart valve	0.826	0.173	0.000
M21 Other acquired deformities of limbs	0.826	0.174	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.825	0.175	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.822	0.178	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.821	0.179	0.000
D50 Iron deficiency anaemia	0.817	0.183	0.000
M81 Osteoporosis without pathological fracture	0.816	0.184	0.000
S90-S99 Injuries to the ankle and foot	0.814	0.186	0.000
I42 Cardiomyopathy	0.812	0.188	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.810	0.190	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.807	0.193	0.000
M05-M14 Inflammatory polyarthropathies	0.804	0.196	0.000
Z95.2 Presence of prosthetic heart valve	0.803	0.197	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.802	0.198	0.000
Z91.5 Personal history of self-harm	0.802	0.198	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.801	0.199	0.000
M80 Osteoporosis with pathological fracture	0.800	0.200	0.000
T66-T78 Other and unspecified effects of external causes	0.799	0.201	0.000
Z91.6 Personal history of other physical trauma	0.799	0.201	0.000
H72 Perforation of tympanic membrane	0.797	0.203	0.000
I44.7 Left bundle-branch block, unspecified	0.794	0.206	0.000
M51.2 Other specified intervertebral disk displacement	0.794	0.206	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.792	0.208	0.000
I30 Acute pericarditis	0.791	0.209	0.000
M86-M90 Other osteopathies	0.791	0.209	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.790	0.210	0.000
I25.5 Ischaemic cardiomyopathy	0.789	0.211	0.000
M91-M94 Chondropathies	0.788	0.212	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.787	0.213	0.000
S10-S19 Injuries to the neck	0.787	0.213	0.000
M50 Cervical disk disorders	0.786	0.214	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.781	0.219	0.000
M24 Other specific joint derangements	0.779	0.221	0.000
I37 Pulmonary valve disorders	0.778	0.222	0.000
I50.9 Heart failure, unspecified	0.775	0.225	0.000
B35-B49 Mycoses	0.775	0.225	0.000
H27 Other disorders of lens	0.774	0.226	0.000
M65 Synovitis and tenosynovitis	0.774	0.226	0.000
D50.8 Other iron deficiency anaemias	0.773	0.227	0.000
S81 Open wound of lower leg	0.771	0.229	0.000
M31 Other necrotising vasculopathies	0.768	0.232	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.767	0.232	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.766	0.234	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.766	0.234	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.766	0.234	0.000
H54 Blindness and low vision	0.763	0.237	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.762	0.238	0.000
M34 Systemic sclerosis	0.760	0.240	0.000
H10-H13 Disorders of conjunctiva	0.759	0.241	0.000
Z97.8 Presence of other specified devices	0.756	0.244	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.753	0.247	0.000
S32 Fracture of lumbar spine and pelvis	0.753	0.247	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.752	0.248	0.000
I45.1 Other and unspecified right bundle-branch block	0.751	0.249	0.000
H25.9 Senile cataract, unspecified	0.751	0.249	0.000
M25.46 Effusion of joint (Lower leg)	0.750	0.250	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.749	0.250	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.749	0.251	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.747	0.253	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.745	0.255	0.000
H74 Other disorders of middle ear and mastoid	0.744	0.256	0.000
S89 Other and unspecified injuries of lower leg	0.743	0.257	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.741	0.258	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.741	0.259	0.000
M25.9 Joint disorder, unspecified	0.741	0.259	0.000
Q60-Q64 Congenital malformations of the urinary system	0.733	0.267	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.733	0.267	0.000
S50-S59 Injuries to the elbow and forearm	0.733	0.267	0.000
S70-S79 Injuries to the hip and thigh	0.733	0.267	0.000
I25.3 Aneurysm of heart	0.731	0.268	0.000
Z92 Personal history of medical treatment	0.731	0.269	0.000
M25.8 Other specified joint disorders	0.730	0.269	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.730	0.270	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.730	0.270	0.000
M81.9 Osteoporosis, unspecified	0.729	0.271	0.000
H90-H95 Other disorders of ear	0.729	0.271	0.000
H65.3 Chronic mucoid otitis media	0.727	0.273	0.000
M84 Disorders of continuity of bone	0.726	0.274	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.726	0.274	0.000
M67 Other disorders of synovium and tendon	0.725	0.275	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.722	0.278	0.000
M23.5 Chronic instability of knee	0.720	0.280	0.000
I10-I15 Hypertensive diseases	0.719	0.281	0.000
M40-M43 Deforming dorsopathies	0.718	0.282	0.000
D51 Vitamin B12 deficiency anaemia	0.718	0.282	0.000
M19.94 Arthrosis, unspecified (Hand)	0.718	0.282	0.000
D50.9 Iron deficiency anaemia, unspecified	0.718	0.282	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
Z84 Family history of other conditions	0.717	0.283	0.000
Z81 Family history of mental and behavioural disorders	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.283	0.000
M33 Dermatopolymyositis	0.716	0.283	0.000
M32 Systemic lupus erythematosus	0.716	0.283	0.000
M30 Polyarteritis nodosa and related conditions	0.716	0.283	0.000
M25.56 Pain in joint (Lower leg)	0.716	0.284	0.000
M15 Polyarthrosis	0.716	0.284	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.715	0.285	0.000
Z91.7 Personal history of female genital mutilation	0.715	0.285	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.715	0.285	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.715	0.285	0.000
Z91.2 Personal history of poor personal hygiene	0.715	0.285	0.000
B15-B19 Viral hepatitis	0.715	0.285	0.000
M53 Other dorsopathies, not elsewhere classified	0.714	0.286	0.000
H53 Visual disturbances	0.714	0.286	0.000
M23.9 Internal derangement of knee, unspecified	0.713	0.287	0.000
M23.1 Discoid meniscus (congenital)	0.713	0.287	0.000
M23.0 Cystic meniscus	0.713	0.287	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.712	0.288	0.000
Z97.4 Presence of external hearing-aid	0.712	0.288	0.000
S40-S49 Injuries to the shoulder and upper arm	0.710	0.290	0.000
I52 Other heart disorders in diseases classified elsewhere	0.708	0.291	0.000
I48 Atrial fibrillation and flutter	0.708	0.291	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.708	0.291	0.000
I41 Myocarditis in diseases classified elsewhere	0.708	0.291	0.000
I40 Acute myocarditis	0.708	0.291	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.708	0.291	0.000
I36 Nonrheumatic tricuspid valve disorders	0.708	0.291	0.000
I32 Pericarditis in diseases classified elsewhere	0.708	0.291	0.000
Z89 Acquired absence of limb	0.708	0.292	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.706	0.293	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.707	0.293	0.000
S83.2 Tear of meniscus, current	0.706	0.294	0.000
M25.3 Other instability of joint	0.705	0.295	0.000
M25.2 Flail joint	0.705	0.295	0.000
M25.1 Fistula of joint	0.705	0.295	0.000
M25.0 Haemarthrosis	0.705	0.295	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.705	0.295	0.000
T33-T35 Frostbite	0.702	0.297	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.702	0.297	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.702	0.297	0.000
T00-T07 Injuries involving multiple body regions	0.702	0.297	0.000
D80-D89 Certain disorders involving the immune mechanism	0.702	0.298	0.000
Chapter XXII Codes for special purposes	0.701	0.298	0.000
M17.5 Other secondary gonarthrosis	0.701	0.299	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.701	0.299	0.000
M17.3 Other posttraumatic gonarthrosis	0.701	0.299	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.701	0.299	0.000
Z98 Other postsurgical states	0.701	0.299	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.700	0.300	0.000
M19.8 Other specified arthrosis	0.699	0.300	0.000
M19.2 Other secondary arthrosis	0.699	0.300	0.000
M19.1 Posttraumatic arthrosis of other joints	0.699	0.300	0.000
I50.0 Congestive heart failure	0.698	0.302	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.698	0.302	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.697	0.303	0.000
M23.4 Loose body in knee	0.696	0.304	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.696	0.304	0.000
M85 Other disorders of bone density and structure	0.695	0.305	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.695	0.305	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.695	0.305	0.000
I35 Nonrheumatic aortic valve disorders	0.694	0.306	0.000
Chapter VI Diseases of the nervous system	0.693	0.307	0.000
Z88.5 Personal history of allergy to narcotic agent	0.693	0.307	0.000
H43-H45 Disorders of vitreous body and globe	0.693	0.307	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.693	0.307	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.691	0.309	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.690	0.310	0.000
B99-B99 Other infectious diseases	0.689	0.311	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.689	0.311	0.000
M22 Disorders of patella	0.689	0.311	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.689	0.311	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.689	0.311	0.000
Z96.9 Presence of functional implant, unspecified	0.689	0.311	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.689	0.311	0.000
Z96.4 Presence of endocrine implants	0.689	0.311	0.000
Z96.3 Presence of artificial larynx	0.689	0.311	0.000
Z96.2 Presence of otological and audiological implants	0.689	0.311	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.688	0.312	0.000
H55 Nystagmus and other irregular eye movements	0.687	0.313	0.000
I20.1 Angina pectoris with documented spasm	0.685	0.314	0.000
B37 Candidiasis	0.685	0.315	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.684	0.316	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.683	0.317	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.682	0.318	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.681	0.319	0.000
I33 Acute and subacute endocarditis	0.681	0.319	0.000
I44.2 Atrioventricular block, complete	0.681	0.319	0.000
M25.47 Effusion of joint (Ankle and foot)	0.680	0.320	0.000
M19.0 Primary arthrosis of other joints	0.680	0.320	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.679	0.321	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.679	0.321	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.679	0.321	0.000
M25.71 Osteophyte (Shoulder region)	0.678	0.322	0.000
H25.2 Senile cataract, morgagnian type	0.678	0.322	0.000
T79-T79 Certain early complications of trauma	0.678	0.322	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.678	0.322	0.000
M25.57 Pain in joint (Ankle and foot)	0.677	0.323	0.000
H69 Other disorders of Eustachian tube	0.676	0.323	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.675	0.325	0.000
H57 Other disorders of eye and adnexa	0.675	0.325	0.000
H40-H42 Glaucoma	0.675	0.325	0.000
H60-H62 Diseases of external ear	0.674	0.326	0.000
S80 Superficial injury of lower leg	0.672	0.328	0.000
M83 Adult osteomalacia	0.672	0.328	0.000
M82 Osteoporosis in diseases classified elsewhere	0.672	0.328	0.000
M50.3 Other cervical disk degeneration	0.671	0.329	0.000
M25.53 Pain in joint (Forearm)	0.671	0.329	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.670	0.329	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.670	0.330	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.670	0.330	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.670	0.330	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.670	0.330	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.670	0.330	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.670	0.330	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.670	0.330	0.000
T36 Poisoning by systemic antibiotics	0.670	0.330	0.000
Z96.7 Presence of other bone and tendon implants	0.669	0.331	0.000
M11 Other crystal arthropathies	0.669	0.331	0.000
I31 Other diseases of pericardium	0.669	0.331	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.669	0.331	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.669	0.331	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.668	0.332	0.000
S90 Superficial injury of ankle and foot	0.667	0.333	0.000
M25.54 Pain in joint (Hand)	0.666	0.334	0.000
I44.6 Other and unspecified fascicular block	0.665	0.335	0.000
I44.5 Left posterior fascicular block	0.665	0.335	0.000
I44.4 Left anterior fascicular block	0.665	0.335	0.000
I44.3 Other and unspecified atrioventricular block	0.665	0.335	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.664	0.336	0.000
S32.0 Fracture of lumbar vertebra	0.663	0.337	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.661	0.339	0.000
Q00-Q07 Congenital malformations of the nervous system	0.661	0.339	0.000
M25.59 Pain in joint (Site unspecified)	0.661	0.339	0.000
M25.58 Pain in joint (Other)	0.661	0.339	0.000
M25.52 Pain in joint (Upper arm)	0.661	0.339	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.660	0.340	0.000
T43.2 Other and unspecified antidepressants	0.659	0.341	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.659	0.341	0.000
S88 Traumatic amputation of lower leg	0.658	0.342	0.000
S87 Crushing injury of lower leg	0.658	0.342	0.000
S86 Injury of muscle and tendon at lower leg level	0.658	0.342	0.000
S85 Injury of blood vessels at lower leg level	0.658	0.342	0.000
S84 Injury of nerves at lower leg level	0.658	0.342	0.000
Z97.3 Presence of spectacles and contact lenses	0.657	0.343	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.657	0.343	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.657	0.343	0.000
Z97.0 Presence of artificial eye	0.657	0.343	0.000
H30-H36 Disorders of choroid and retina	0.654	0.346	0.000
M21.1 Varus deformity, not elsewhere classified	0.653	0.347	0.000
A00-A09 Intestinal infectious diseases	0.651	0.349	0.000
I30.9 Acute pericarditis, unspecified	0.650	0.350	0.000
I22 Subsequent myocardial infarction	0.650	0.350	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.648	0.352	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.648	0.352	0.000
B65-B83 Helminthiases	0.648	0.352	0.000
B50-B64 Protozoal diseases	0.648	0.352	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.648	0.352	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.648	0.352	0.000
A80-A89 Viral infections of the central nervous system	0.648	0.352	0.000
A75-A79 Rickettsioses	0.648	0.352	0.000
A70-A74 Other diseases caused by chlamydiae	0.648	0.352	0.000
A65-A69 Other spirochaetal diseases	0.648	0.352	0.000
A20-A28 Certain zoonotic bacterial diseases	0.648	0.352	0.000
A15-A19 Tuberculosis	0.648	0.352	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.648	0.352	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.648	0.352	0.000
H54.0 Blindness, both eyes	0.648	0.352	0.000
M06 Other rheumatoid arthritis	0.647	0.353	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.647	0.353	0.000
H70 Mastoiditis and related conditions	0.647	0.353	0.000
H68 Eustachian salpingitis and obstruction	0.647	0.353	0.000
H67 Otitis media in diseases classified elsewhere	0.647	0.353	0.000
M25.78 Osteophyte (Other)	0.647	0.353	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.646	0.354	0.000
M23.37 Other meniscus derangements-Capsular lig	0.646	0.354	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.646	0.354	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.646	0.354	0.000
I44.1 Atrioventricular block, second degree	0.646	0.354	0.000
T45.0 Antiallergic and antiemetic drugs	0.646	0.354	0.000
S20-S29 Injuries to the thorax	0.645	0.355	0.000
T78 Adverse effects, not elsewhere classified	0.644	0.356	0.000
H72.8 Other perforations of tympanic membrane	0.644	0.356	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.643	0.357	0.000
H80-H83 Diseases of inner ear	0.643	0.357	0.000
M21.0 Valgus deformity, not elsewhere classified	0.643	0.357	0.000
I42.0 Dilated cardiomyopathy	0.642	0.358	0.000
H27.1 Dislocation of lens	0.641	0.359	0.000
Z95.4 Presence of other heart-valve replacement	0.641	0.359	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.640	0.360	0.000
M19.98 Arthrosis, unspecified (Other)	0.639	0.360	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.639	0.361	0.000
M66 Spontaneous rupture of synovium and tendon	0.639	0.361	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.638	0.362	0.000
Q80-Q89 Other congenital malformations	0.638	0.362	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.638	0.362	0.000
Q50-Q56 Congenital malformations of genital organs	0.638	0.362	0.000
Q35-Q37 Cleft lip and cleft palate	0.638	0.362	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.638	0.362	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.638	0.362	0.000
I45.5 Other specified heart block	0.636	0.364	0.000
M94 Other disorders of cartilage	0.635	0.364	0.000
S82 Fracture of lower leg, including ankle	0.635	0.365	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.634	0.366	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.634	0.366	0.000
M25.76 Osteophyte (Lower leg)	0.632	0.368	0.000
M51.3 Other specified intervertebral disk degeneration	0.628	0.372	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.628	0.372	0.000
M51.9 Intervertebral disk disorder, unspecified	0.628	0.372	0.000
M51.8 Other specified intervertebral disk disorders	0.628	0.372	0.000
M51.4 Schmorl's nodes	0.628	0.372	0.000
I37.1 Pulmonary valve insufficiency	0.628	0.372	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.628	0.372	0.000
I42.8 Other cardiomyopathies	0.627	0.372	0.000
Z82.3 Family history of stroke	0.627	0.373	0.000
S10 Superficial injury of neck	0.624	0.376	0.000
I49 Other cardiac arrhythmias	0.623	0.377	0.000
S81.9 Open wound of lower leg, part unspecified	0.623	0.377	0.000
M81.98 Osteoporosis, unspecified (Other)	0.622	0.378	0.000
S81.0 Open wound of knee	0.621	0.379	0.000
S92 Fracture of foot, except ankle	0.621	0.379	0.000
H18 Other disorders of cornea	0.621	0.379	0.000
D55-D59 Haemolytic anaemias	0.620	0.380	0.000
H46 Optic neuritis	0.620	0.380	0.000
T63 Toxic effect of contact with venomous animals	0.620	0.380	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.620	0.380	0.000
M25.49 Effusion of joint (Site unspecified)	0.620	0.380	0.000
M25.48 Effusion of joint (Other)	0.620	0.380	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.620	0.380	0.000
M25.44 Effusion of joint (Hand)	0.620	0.380	0.000
M25.43 Effusion of joint (Forearm)	0.620	0.380	0.000
M25.42 Effusion of joint (Upper arm)	0.620	0.380	0.000
M25.41 Effusion of joint (Shoulder region)	0.620	0.380	0.000
M25.40 Effusion of joint (Multiple sites)	0.620	0.380	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.619	0.381	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.619	0.381	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.619	0.381	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.619	0.381	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.619	0.381	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.619	0.381	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.619	0.381	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.618	0.382	0.000
M90 Osteopathies in diseases classified elsewhere	0.618	0.382	0.000
S89.9 Unspecified injury of lower leg	0.618	0.382	0.000
I12 Hypertensive renal disease	0.617	0.383	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.616	0.383	0.000
Z96.1 Presence of intraocular lens	0.615	0.385	0.000
B37.0 Candidal stomatitis	0.615	0.385	0.000
M16 Coxarthrosis [arthrosis of hip]	0.614	0.386	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.614	0.386	0.000
M21.3 Wrist or foot drop (acquired)	0.613	0.387	0.000
H74.0 Tympanosclerosis	0.613	0.387	0.000
T40.2 Other opioids	0.612	0.388	0.000
I45.8 Other specified conduction disorders	0.612	0.388	0.000
I45.6 Preexcitation syndrome	0.612	0.388	0.000
I45.4 Nonspecific intraventricular block	0.612	0.388	0.000
I45.3 Trifascicular block	0.612	0.388	0.000
I45.2 Bifascicular block	0.612	0.388	0.000
I45.0 Right fascicular block	0.612	0.388	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.611	0.389	0.000
M07 Psoriatic and enteropathic arthropathies	0.611	0.389	0.000
M89 Other disorders of bone	0.610	0.389	0.000
H53.8 Other visual disturbances	0.610	0.390	0.000
S32.1 Fracture of sacrum	0.609	0.390	0.000
H53.0 Amblyopia ex anopsia	0.609	0.391	0.000
H71 Cholesteatoma of middle ear	0.609	0.391	0.000
T68 Hypothermia	0.608	0.392	0.000
H65.4 Other chronic nonsuppurative otitis media	0.607	0.393	0.000
H65.2 Chronic serous otitis media	0.607	0.393	0.000
H65.1 Other acute nonsuppurative otitis media	0.607	0.393	0.000
H65.0 Acute serous otitis media	0.607	0.393	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.606	0.394	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.606	0.394	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.606	0.394	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.606	0.394	0.000
T14 Injury of unspecified body region	0.606	0.394	0.000
D53 Other nutritional anaemias	0.606	0.394	0.000
D52 Folate deficiency anaemia	0.606	0.394	0.000
M31.6 Other giant cell arteritis	0.605	0.395	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.604	0.396	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.603	0.397	0.000
M24.5 Contracture of joint	0.603	0.397	0.000
H54.4 Blindness, one eye	0.601	0.399	0.000
I24.1 Dressler's syndrome	0.600	0.400	0.000
G90-G99 Other disorders of the nervous system	0.600	0.400	0.000
I45.9 Conduction disorder, unspecified	0.600	0.400	0.000
H73 Other disorders of tympanic membrane	0.600	0.400	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.598	0.402	0.000
I42.9 Cardiomyopathy, unspecified	0.598	0.402	0.000
S12 Fracture of neck	0.597	0.403	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.597	0.403	0.000
M17.0 Primary gonarthrosis, bilateral	0.597	0.403	0.000
H11 Other disorders of conjunctiva	0.596	0.404	0.000
Q61 Cystic kidney disease	0.596	0.404	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.595	0.404	0.000
S37 Injury of urinary and pelvic organs	0.595	0.404	0.000
S36 Injury of intra-abdominal organs	0.595	0.404	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.595	0.404	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.595	0.404	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.595	0.404	0.000
S31 Open wound of abdomen, lower back and pelvis	0.595	0.404	0.000
M67.1 Other contracture of tendon (sheath)	0.595	0.405	0.000
M25.79 Osteophyte (Site unspecified)	0.594	0.406	0.000
M25.73 Osteophyte (Forearm)	0.594	0.406	0.000
M25.72 Osteophyte (Upper arm)	0.594	0.406	0.000
M25.70 Osteophyte (Multiple sites)	0.594	0.406	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.593	0.406	0.000
S91 Open wound of ankle and foot	0.593	0.407	0.000
I05-I09 Chronic rheumatic heart diseases	0.592	0.407	0.000
M21.9 Acquired deformity of limb, unspecified	0.592	0.407	0.000
M21.8 Other specified acquired deformities of limbs	0.592	0.407	0.000
M21.7 Unequal limb length (acquired)	0.592	0.407	0.000
M21.6 Other acquired deformities of ankle and foot	0.592	0.407	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.592	0.407	0.000
M21.4 Flat foot [pes planus] (acquired)	0.592	0.407	0.000
M21.2 Flexion deformity	0.592	0.407	0.000
M65.3 Trigger finger	0.592	0.408	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.590	0.410	0.000
T43.9 Psychotropic drug, unspecified	0.589	0.411	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.589	0.411	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations