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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62402484
log Bayes Factor = 15.7618
Chromosome 6   position 21,913,816  (GRCh37) Explore rs62402484 on Ensembl!
Variant rs62402484 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
I20 Angina pectoris
0.997 0.003 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
Z86 Personal history of certain other diseases
0.995 0.005 0.000
Z86.7 Personal history of diseases of the circulatory system
0.993 0.007 0.000
I20.9 Angina pectoris, unspecified
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.979 0.021 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.973 0.027 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.971 0.029 0.000
I60-I69 Cerebrovascular diseases
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
M23 Internal derangement of knee
0.962 0.038 0.000
Chapter I Certain infectious and parasitic diseases
0.959 0.041 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.958 0.042 0.000
M15-M19 Arthrosis
0.957 0.043 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.946 0.054 0.000
I25.2 Old myocardial infarction
0.945 0.055 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.939 0.061 0.000
Z96 Presence of other functional implants
0.935 0.065 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.934 0.066 0.000
M20 Acquired deformities of fingers and toes
0.932 0.068 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.927 0.073 0.000
M06 Other rheumatoid arthritis
0.927 0.073 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.925 0.075 0.000
S40-S49 Injuries to the shoulder and upper arm
0.919 0.081 0.000
M50-M54 Other dorsopathies
0.915 0.085 0.000
A30-A49 Other bacterial diseases
0.914 0.086 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.911 0.089 0.000
I67 Other cerebrovascular diseases
0.905 0.095 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.903 0.097 0.000
M13 Other arthritis
0.902 0.098 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.895 0.105 0.000
Z95.1 Presence of aortocoronary bypass graft
0.894 0.106 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.891 0.109 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.890 0.110 0.000
M06.9 Rheumatoid arthritis, unspecified
0.888 0.112 0.000
M20.5 Other deformities of toe(s) (acquired)
0.887 0.113 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.878 0.122 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.878 0.122 0.000
M17 Gonarthrosis [arthrosis of knee]
0.878 0.122 0.000
Z96.6 Presence of orthopaedic joint implants
0.877 0.123 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.868 0.132 0.000
M16 Coxarthrosis [arthrosis of hip]
0.866 0.134 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.863 0.137 0.000
Chapter VII Diseases of the eye and adnexa
0.862 0.138 0.000
A41 Other septicaemia
0.862 0.138 0.000
M80-M85 Disorders of bone density and structure
0.862 0.138 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.855 0.145 0.000
I22 Subsequent myocardial infarction
0.854 0.146 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.854 0.146 0.000
I25.5 Ischaemic cardiomyopathy
0.852 0.148 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.850 0.150 0.000
Z92 Personal history of medical treatment
0.849 0.151 0.000
T39.1 4-Aminophenol derivatives
0.847 0.153 0.000
M13.9 Arthritis, unspecified
0.846 0.154 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.846 0.154 0.000
I80 Phlebitis and thrombophlebitis
0.846 0.154 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.845 0.155 0.000
M65-M68 Disorders of synovium and tendon
0.844 0.156 0.000
B35-B49 Mycoses
0.842 0.158 0.000
I12 Hypertensive renal disease
0.839 0.161 0.000
M17.9 Gonarthrosis, unspecified
0.839 0.161 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.833 0.167 0.000
M25 Other joint disorders, not elsewhere classified
0.833 0.167 0.000
I20.8 Other forms of angina pectoris
0.829 0.171 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
I25.1 Atherosclerotic heart disease
0.824 0.176 0.000
I70 Atherosclerosis
0.817 0.183 0.000
M45-M49 Spondylopathies
0.815 0.185 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.814 0.186 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.813 0.187 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.812 0.188 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.811 0.189 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.810 0.190 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.809 0.191 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.809 0.191 0.000
Chapter V Mental and behavioural disorders
0.803 0.197 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.801 0.199 0.000
M18 Arthrosis of first carpometacarpal joint
0.801 0.199 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.799 0.201 0.000
Z96.8 Presence of other specified functional implants
0.796 0.203 0.000
I20.0 Unstable angina
0.793 0.207 0.000
M51 Other intervertebral disk disorders
0.793 0.207 0.000
M91-M94 Chondropathies
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.792 0.208 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.789 0.211 0.000
Z88.0 Personal history of allergy to penicillin
0.787 0.213 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.785 0.215 0.000
M22 Disorders of patella
0.784 0.216 0.000
G90-G99 Other disorders of the nervous system
0.784 0.216 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.781 0.219 0.000
I67.9 Cerebrovascular disease, unspecified
0.780 0.220 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.779 0.221 0.000
S42 Fracture of shoulder and upper arm
0.778 0.222 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.778 0.222 0.000
M23.8 Other internal derangements of knee
0.778 0.222 0.000
T93 Sequelae of injuries of lower limb
0.777 0.223 0.000
Z92.8 Personal history of other medical treatment
0.777 0.223 0.000
H30-H36 Disorders of choroid and retina
0.776 0.224 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.775 0.225 0.000
I67.8 Other specified cerebrovascular diseases
0.773 0.227 0.000
S50-S59 Injuries to the elbow and forearm
0.773 0.227 0.000
E70-E90 Metabolic disorders
0.770 0.229 0.000
B07 Viral warts
0.768 0.232 0.000
M50 Cervical disk disorders
0.768 0.232 0.000
I61 Intracerebral haemorrhage
0.767 0.233 0.000
M31 Other necrotising vasculopathies
0.766 0.234 0.000
T92 Sequelae of injuries of upper limb
0.765 0.234 0.000
M86-M90 Other osteopathies
0.765 0.235 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.761 0.239 0.000
M16.1 Other primary coxarthrosis
0.759 0.241 0.000
T43.2 Other and unspecified antidepressants
0.759 0.241 0.000
B25-B34 Other viral diseases
0.758 0.242 0.000
M20.0 Deformity of finger(s)
0.756 0.244 0.000
I74 Arterial embolism and thrombosis
0.756 0.244 0.000
Z94 Transplanted organ and tissue status
0.756 0.244 0.000
Z29 Need for other prophylactic measures
0.753 0.247 0.000
A49 Bacterial infection of unspecified site
0.753 0.247 0.000
M17.5 Other secondary gonarthrosis
0.752 0.248 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.752 0.248 0.000
M40-M43 Deforming dorsopathies
0.751 0.249 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
A41.9 Septicaemia, unspecified
0.750 0.250 0.000
Z95.2 Presence of prosthetic heart valve
0.749 0.251 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.749 0.251 0.000
M20.1 Hallux valgus (acquired)
0.747 0.253 0.000
Z80 Family history of malignant neoplasm
0.745 0.255 0.000
Z91.5 Personal history of self-harm
0.744 0.256 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.743 0.257 0.000
M25.7 Osteophyte
0.743 0.257 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.743 0.257 0.000
G30-G32 Other degenerative diseases of the nervous system
0.742 0.258 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.741 0.259 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.261 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.738 0.262 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.737 0.262 0.000
I20.1 Angina pectoris with documented spasm
0.736 0.264 0.000
M21 Other acquired deformities of limbs
0.735 0.265 0.000
B37 Candidiasis
0.735 0.265 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.735 0.265 0.000
Z97 Presence of other devices
0.733 0.266 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.732 0.268 0.000
M05 Seropositive rheumatoid arthritis
0.732 0.268 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.729 0.270 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.729 0.271 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.729 0.271 0.000
M65 Synovitis and tenosynovitis
0.729 0.271 0.000
G50 Disorders of trigeminal nerve
0.728 0.272 0.000
T39.0 Salicylates
0.727 0.273 0.000
I12.0 Hypertensive renal disease with renal failure
0.724 0.275 0.000
E78.5 Hyperlipidaemia, unspecified
0.724 0.276 0.000
M23.5 Chronic instability of knee
0.724 0.276 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.721 0.279 0.000
M20.3 Other deformity of hallux (acquired)
0.720 0.280 0.000
M80 Osteoporosis with pathological fracture
0.719 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I15 Secondary hypertension
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
I11 Hypertensive heart disease
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.3 Aneurysm of heart
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
Z88.5 Personal history of allergy to narcotic agent
0.715 0.285 0.000
I78 Diseases of capillaries
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M34 Systemic sclerosis
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.713 0.287 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.713 0.287 0.000
Z95.3 Presence of xenogenic heart valve
0.712 0.288 0.000
G58 Other mononeuropathies
0.712 0.288 0.000
M51.2 Other specified intervertebral disk displacement
0.709 0.291 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.709 0.291 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
E20-E35 Disorders of other endocrine glands
0.708 0.292 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.292 0.000
E78.0 Pure hypercholesterolaemia
0.707 0.293 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.706 0.294 0.000
T51 Toxic effect of alcohol
0.706 0.294 0.000
I30-I52 Other forms of heart disease
0.705 0.295 0.000
H53-H54 Visual disturbances and blindness
0.704 0.296 0.000
I67.2 Cerebral atherosclerosis
0.702 0.298 0.000
M24 Other specific joint derangements
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
M07 Psoriatic and enteropathic arthropathies
0.702 0.298 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.702 0.298 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.702 0.298 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.702 0.298 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.702 0.298 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.702 0.298 0.000
S90-S99 Injuries to the ankle and foot
0.700 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
M16.9 Coxarthrosis, unspecified
0.700 0.300 0.000
O60-O75 Complications of labour and delivery
0.699 0.301 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.697 0.303 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.696 0.304 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.696 0.304 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.696 0.304 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.696 0.304 0.000
Z82.2 Family history of deafness and hearing loss
0.696 0.304 0.000
Z82.1 Family history of blindness and visual loss
0.696 0.304 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.696 0.304 0.000
Z98 Other postsurgical states
0.696 0.304 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.695 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.695 0.304 0.000
I62 Other nontraumatic intracranial haemorrhage
0.695 0.304 0.000
I82 Other venous embolism and thrombosis
0.695 0.305 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.694 0.306 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.693 0.307 0.000
M84 Disorders of continuity of bone
0.693 0.307 0.000
H50 Other strabismus
0.693 0.307 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.693 0.307 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.693 0.307 0.000
M54 Dorsalgia
0.692 0.308 0.000
I73 Other peripheral vascular diseases
0.691 0.309 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.690 0.309 0.000
M23.9 Internal derangement of knee, unspecified
0.690 0.310 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.690 0.310 0.000
M23.4 Loose body in knee
0.690 0.310 0.000
M23.1 Discoid meniscus (congenital)
0.690 0.310 0.000
M23.0 Cystic meniscus
0.690 0.310 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.689 0.310 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.689 0.311 0.000
B99-B99 Other infectious diseases
0.688 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.688 0.312 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.688 0.312 0.000
B65-B83 Helminthiases
0.688 0.312 0.000
B50-B64 Protozoal diseases
0.688 0.312 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.688 0.312 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.688 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.312 0.000
A75-A79 Rickettsioses
0.688 0.312 0.000
A70-A74 Other diseases caused by chlamydiae
0.688 0.312 0.000
A65-A69 Other spirochaetal diseases
0.688 0.312 0.000
A20-A28 Certain zoonotic bacterial diseases
0.688 0.312 0.000
A15-A19 Tuberculosis
0.688 0.312 0.000
M15 Polyarthrosis
0.686 0.314 0.000
I60 Subarachnoid haemorrhage
0.685 0.315 0.000
M66 Spontaneous rupture of synovium and tendon
0.685 0.315 0.000
M10 Gout
0.685 0.315 0.000
Z83 Family history of other specific disorders
0.685 0.315 0.000
Z95.4 Presence of other heart-valve replacement
0.684 0.316 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.684 0.316 0.000
I72 Other aneurysm
0.683 0.317 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.683 0.317 0.000
M11 Other crystal arthropathies
0.682 0.318 0.000
S42.4 Fracture of lower end of humerus
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
G54 Nerve root and plexus disorders
0.678 0.321 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.678 0.321 0.000
G52 Disorders of other cranial nerves
0.678 0.321 0.000
I69 Sequelae of cerebrovascular disease
0.678 0.321 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.323 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.677 0.323 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.676 0.324 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.676 0.324 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.675 0.325 0.000
M06.0 Seronegative rheumatoid arthritis
0.675 0.325 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.674 0.326 0.000
B37.8 Candidiasis of other sites
0.674 0.326 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.673 0.327 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.673 0.327 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.673 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.672 0.327 0.000
H35 Other retinal disorders
0.672 0.328 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.672 0.328 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.671 0.329 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.671 0.329 0.000
Z96.9 Presence of functional implant, unspecified
0.670 0.330 0.000
Z96.7 Presence of other bone and tendon implants
0.670 0.330 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.670 0.330 0.000
Z96.4 Presence of endocrine implants
0.670 0.330 0.000
Z96.3 Presence of artificial larynx
0.670 0.330 0.000
Z96.2 Presence of otological and audiological implants
0.670 0.330 0.000
M35 Other systemic involvement of connective tissue
0.670 0.330 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.668 0.332 0.000
I67.1 Cerebral aneurysm, nonruptured
0.668 0.332 0.000
I77 Other disorders of arteries and arterioles
0.668 0.332 0.000
Z96.1 Presence of intraocular lens
0.668 0.332 0.000
T81 Complications of procedures, not elsewhere classified
0.667 0.333 0.000
Z95.0 Presence of cardiac pacemaker
0.667 0.333 0.000
I05-I09 Chronic rheumatic heart diseases
0.666 0.334 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.665 0.335 0.000
M06.8 Other specified rheumatoid arthritis
0.664 0.335 0.000
M06.4 Inflammatory polyarthropathy
0.664 0.335 0.000
M06.3 Rheumatoid nodule
0.664 0.335 0.000
M06.2 Rheumatoid bursitis
0.664 0.335 0.000
M06.1 Adult-onset Still's disease
0.664 0.335 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.663 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.663 0.337 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.663 0.337 0.000
F99-F99 Unspecified mental disorder
0.661 0.339 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.660 0.340 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.659 0.341 0.000
S48 Traumatic amputation of shoulder and upper arm
0.659 0.341 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.659 0.341 0.000
S44 Injury of nerves at shoulder and upper arm level
0.659 0.341 0.000
S41 Open wound of shoulder and upper arm
0.659 0.341 0.000
S40 Superficial injury of shoulder and upper arm
0.659 0.341 0.000
S47 Crushing injury of shoulder and upper arm
0.659 0.341 0.000
I42 Cardiomyopathy
0.659 0.341 0.000
B35 Dermatophytosis
0.657 0.343 0.000
M53 Other dorsopathies, not elsewhere classified
0.656 0.344 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.656 0.344 0.000
A48 Other bacterial diseases, not elsewhere classified
0.655 0.345 0.000
A44 Bartonellosis
0.655 0.345 0.000
A43 Nocardiosis
0.655 0.345 0.000
A42 Actinomycosis
0.655 0.345 0.000
A40 Streptococcal septicaemia
0.655 0.345 0.000
A39 Meningococcal infection
0.655 0.345 0.000
A37 Whooping cough
0.655 0.345 0.000
A36 Diphtheria
0.655 0.345 0.000
A32 Listeriosis
0.655 0.345 0.000
A31 Infection due to other mycobacteria
0.655 0.345 0.000
A30 Leprosy [Hansen's disease]
0.655 0.345 0.000
A46 Erysipelas
0.655 0.345 0.000
A38 Scarlet fever
0.655 0.345 0.000
A35 Other tetanus
0.655 0.345 0.000
A34 Obstetrical tetanus
0.655 0.345 0.000
A33 Tetanus neonatorum
0.655 0.345 0.000
T40.4 Other synthetic narcotics
0.655 0.345 0.000
M13.93 Arthritis, unspecified (Forearm)
0.654 0.346 0.000
E10-E14 Diabetes mellitus
0.654 0.346 0.000
I21 Acute myocardial infarction
0.654 0.346 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.653 0.347 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.653 0.347 0.000
T39.4 Antirheumatics, not elsewhere classified
0.653 0.347 0.000
T39.2 Pyrazolone derivatives
0.653 0.347 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.653 0.347 0.000
I26 Pulmonary embolism
0.652 0.348 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.652 0.348 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.650 0.350 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.649 0.350 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.649 0.351 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.649 0.351 0.000
I67.5 Moyamoya disease
0.649 0.351 0.000
I67.4 Hypertensive encephalopathy
0.649 0.351 0.000
I67.3 Progressive vascular leukoencephalopathy
0.649 0.351 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.649 0.351 0.000
T98 Sequelae of other and unspecified effects of external causes
0.647 0.352 0.000
T95 Sequelae of burns, corrosions and frostbite
0.647 0.352 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.647 0.352 0.000
T91 Sequelae of injuries of neck and trunk
0.647 0.352 0.000
T90 Sequelae of injuries of head
0.647 0.352 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.647 0.352 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.647 0.352 0.000
G93 Other disorders of brain
0.647 0.353 0.000
M13.8 Other specified arthritis
0.647 0.353 0.000
M13.1 Monoarthritis, not elsewhere classified
0.647 0.353 0.000
M13.0 Polyarthritis, unspecified
0.647 0.353 0.000
M17.0 Primary gonarthrosis, bilateral
0.647 0.353 0.000
E40-E46 Malnutrition
0.646 0.354 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.646 0.354 0.000
I70.0 Atherosclerosis of aorta
0.646 0.354 0.000
M16.0 Primary coxarthrosis, bilateral
0.645 0.354 0.000
I65.2 Occlusion and stenosis of carotid artery
0.645 0.355 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.645 0.355 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.644 0.356 0.000
M25.4 Effusion of joint
0.644 0.356 0.000
M94 Other disorders of cartilage
0.644 0.356 0.000
A49.0 Staphylococcal infection, unspecified
0.643 0.357 0.000
Z29.2 Other prophylactic chemotherapy
0.643 0.357 0.000
M23.3 Other meniscus derangements
0.643 0.357 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.642 0.358 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.642 0.358 0.000
M99 Biomechanical lesions, not elsewhere classified
0.642 0.358 0.000
S42.2 Fracture of upper end of humerus
0.642 0.358 0.000
G95 Other diseases of spinal cord
0.639 0.360 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.639 0.361 0.000
M50.1 Cervical disk disorder with radiculopathy
0.639 0.361 0.000
T43.9 Psychotropic drug, unspecified
0.639 0.361 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.639 0.361 0.000
T43.6 Psychostimulants with abuse potential
0.639 0.361 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.639 0.361 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.639 0.361 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.639 0.361 0.000
M22.2 Patellofemoral disorders
0.639 0.361 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.638 0.362 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.637 0.363 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.637 0.363 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.637 0.363 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.637 0.363 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.637 0.363 0.000
S20-S29 Injuries to the thorax
0.636 0.364 0.000
I87 Other disorders of veins
0.635 0.364 0.000
M48 Other spondylopathies
0.635 0.365 0.000
S60-S69 Injuries to the wrist and hand
0.635 0.365 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.635 0.365 0.000
H33 Retinal detachments and breaks
0.635 0.365 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.634 0.366 0.000
Q60-Q64 Congenital malformations of the urinary system
0.634 0.366 0.000
H43-H45 Disorders of vitreous body and globe
0.634 0.366 0.000
T40.2 Other opioids
0.632 0.367 0.000
M65.3 Trigger finger
0.631 0.369 0.000
O00-O08 Pregnancy with abortive outcome
0.630 0.370 0.000
M46 Other inflammatory spondylopathies
0.630 0.370 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.630 0.370 0.000
I88 Nonspecific lymphadenitis
0.629 0.370 0.000
I86 Varicose veins of other sites
0.629 0.370 0.000
I81 Portal vein thrombosis
0.629 0.370 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.629 0.371 0.000
Z91.7 Personal history of female genital mutilation
0.629 0.371 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.629 0.371 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.629 0.371 0.000
Z91.2 Personal history of poor personal hygiene
0.629 0.371 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.629 0.371 0.000
M17.3 Other posttraumatic gonarthrosis
0.629 0.371 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.629 0.371 0.000
H55-H59 Other disorders of eye and adnexa
0.629 0.371 0.000
G40-G47 Episodic and paroxysmal disorders
0.628 0.372 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.626 0.374 0.000
S50 Superficial injury of forearm
0.625 0.375 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.623 0.377 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.622 0.378 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.621 0.379 0.000
M16.7 Other secondary coxarthrosis
0.621 0.379 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.621 0.379 0.000
M16.5 Other posttraumatic coxarthrosis
0.621 0.379 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.621 0.379 0.000
M16.3 Other dysplastic coxarthrosis
0.621 0.379 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.621 0.379 0.000
H35.0 Background retinopathy and retinal vascular changes
0.621 0.379 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.620 0.380 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.619 0.381 0.000
T87 Complications peculiar to reattachment and amputation
0.618 0.381 0.000
T86 Failure and rejection of transplanted organs and tissues
0.618 0.381 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.618 0.381 0.000
A41.4 Septicaemia due to anaerobes
0.618 0.382 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.618 0.382 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.618 0.382 0.000
M85 Other disorders of bone density and structure
0.618 0.382 0.000
M83 Adult osteomalacia
0.618 0.382 0.000
M82 Osteoporosis in diseases classified elsewhere
0.618 0.382 0.000
I71 Aortic aneurysm and dissection
0.617 0.382 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.617 0.383 0.000
T42.4 Benzodiazepines
0.616 0.384 0.000
M81 Osteoporosis without pathological fracture
0.616 0.384 0.000
M70-M79 Other soft tissue disorders
0.616 0.384 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.616 0.384 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.616 0.384 0.000
G30 Alzheimer's disease
0.615 0.385 0.000
Z29.0 Isolation
0.615 0.385 0.000
B34 Viral infection of unspecified site
0.614 0.386 0.000
I63 Cerebral infarction
0.613 0.387 0.000
A41.8 Other specified septicaemia
0.613 0.387 0.000
S42.40 Fracture of lower end of humerus (closed)
0.613 0.387 0.000
I22.8 Subsequent myocardial infarction of other sites
0.612 0.388 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.612 0.388 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.612 0.388 0.000
Z28 Immunisation not carried out
0.612 0.388 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.612 0.388 0.000
Z26 Need for immunisation against other single infectious diseases
0.612 0.388 0.000
Z25 Need for immunisation against other single viral diseases
0.612 0.388 0.000
Z24 Need for immunisation against certain single viral diseases
0.612 0.388 0.000
Z23 Need for immunisation against single bacterial diseases
0.612 0.388 0.000
Z20 Contact with and exposure to communicable diseases
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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