TreeWAS – Variant ID: rs6457690

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	0.998	0.002	0.000
E10.3 With ophthalmic complications	0.996	0.004	0.000
E10.1 With ketoacidosis	0.984	0.016	0.000
E10.5 With peripheral circulatory complications	0.955	0.045	0.000
E10.9 Without complications	0.940	0.060	0.000
E10.4 With neurological complications	0.927	0.073	0.000
E10.8 With unspecified complications	0.875	0.125	0.000
E10.2 With renal complications	0.845	0.155	0.000
E10.0 With coma	0.826	0.174	0.000
E10.6 With other specified complications	0.768	0.232	0.000
E10.7 With multiple complications	0.716	0.284	0.000
E10-E14 Diabetes mellitus	0.181	0.819	0.000
E13 Other specified diabetes mellitus	0.133	0.867	0.000
E12 Malnutrition-related diabetes mellitus	0.130	0.870	0.000
E14 Unspecified diabetes mellitus	0.107	0.893	0.000
E13.9 Without complications	0.099	0.901	0.000
E13.8 With unspecified complications	0.096	0.904	0.000
E13.7 With multiple complications	0.096	0.904	0.000
E13.6 With other specified complications	0.096	0.904	0.000
E13.5 With peripheral circulatory complications	0.096	0.904	0.000
E13.4 With neurological complications	0.096	0.904	0.000
E13.3 With ophthalmic complications	0.096	0.904	0.000
E13.2 With renal complications	0.096	0.904	0.000
E13.1 With ketoacidosis	0.096	0.904	0.000
E13.0 With coma	0.096	0.904	0.000
E14.8 With unspecified complications	0.094	0.906	0.000
E12.9 Without complications	0.093	0.906	0.000
E12.8 With unspecified complications	0.093	0.906	0.000
E12.7 With multiple complications	0.093	0.906	0.000
E12.6 With other specified complications	0.093	0.906	0.000
E12.5 With peripheral circulatory complications	0.093	0.906	0.000
E12.4 With neurological complications	0.093	0.906	0.000
E12.3 With ophthalmic complications	0.093	0.906	0.000
E12.2 With renal complications	0.093	0.906	0.000
E12.1 With ketoacidosis	0.093	0.906	0.000
E12.0 With coma	0.093	0.906	0.000
E14.7 With multiple complications	0.077	0.923	0.000
E14.6 With other specified complications	0.077	0.923	0.000
E14.5 With peripheral circulatory complications	0.077	0.923	0.000
E14.4 With neurological complications	0.077	0.923	0.000
E14.2 Withrenal complications	0.077	0.923	0.000
E14.1 With ketoacidosis	0.077	0.923	0.000
E14.0 With coma	0.077	0.923	0.000
E14.3 With ophthalmic complications	0.070	0.930	0.000
E11 Non-insulin-dependent diabetes mellitus	0.041	0.959	0.000
K90.0 Coeliac disease	0.000	0.966	0.034
E11.5 With peripheral circulatory complications	0.033	0.967	0.000
E11.6 With other specified complications	0.030	0.970	0.000
E11.0 With coma	0.030	0.970	0.000
E11.7 With multiple complications	0.029	0.971	0.000
E11.3 With ophthalmic complications	0.029	0.971	0.000
E11.1 With ketoacidosis	0.027	0.972	0.000
E11.2 With renal complications	0.027	0.973	0.000
E11.8 With unspecified complications	0.025	0.975	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.024	0.976	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.021	0.979	0.000
E20-E35 Disorders of other endocrine glands	0.021	0.979	0.000
E16 Other disorders of pancreatic internal secretion	0.019	0.980	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.019	0.981	0.000
E40-E46 Malnutrition	0.019	0.981	0.000
E16.2 Hypoglycaemia, unspecified	0.018	0.982	0.000
E24 Cushing's syndrome	0.018	0.982	0.000
E21.0 Primary hyperparathyroidism	0.017	0.983	0.000
E26 Hyperaldosteronism	0.017	0.983	0.000
E25 Adrenogenital disorders	0.016	0.984	0.000
E50-E64 Other nutritional deficiencies	0.016	0.984	0.000
E11.4 With neurological complications	0.016	0.984	0.000
E28 Ovarian dysfunction	0.016	0.984	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.016	0.984	0.000
E15 Nondiabetic hypoglycaemic coma	0.015	0.984	0.000
K90 Intestinal malabsorption	0.000	0.985	0.015
E35 Disorders of endocrine glands in diseases classified elsewhere	0.015	0.985	0.000
E32 Diseases of thymus	0.015	0.985	0.000
E31 Polyglandular dysfunction	0.015	0.985	0.000
E30 Disorders of puberty, not elsewhere classified	0.015	0.985	0.000
E46 Unspecified protein-energy malnutrition	0.015	0.985	0.000
E34 Other endocrine disorders	0.015	0.985	0.000
E22 Hyperfunction of pituitary gland	0.015	0.985	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.014	0.985	0.000
E20 Hypoparathyroidism	0.014	0.985	0.000
E24.9 Cushing's syndrome, unspecified	0.014	0.986	0.000
E61 Deficiency of other nutrient elements	0.014	0.986	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.014	0.986	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.014	0.986	0.000
E16.4 Abnormal secretion of gastrin	0.014	0.986	0.000
E16.3 Increased secretion of glucagon	0.014	0.986	0.000
E16.1 Other hypoglycaemia	0.014	0.986	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.014	0.986	0.000
E21.4 Other specified disorders of parathyroid gland	0.014	0.986	0.000
E21.2 Other hyperparathyroidism	0.014	0.986	0.000
E29 Testicular dysfunction	0.014	0.986	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.014	0.986	0.000
E45 Retarded development following protein-energy malnutrition	0.014	0.986	0.000
E43 Unspecified severe protein-energy malnutrition	0.014	0.986	0.000
E42 Marasmic kwashiorkor	0.014	0.986	0.000
E41 Nutritional marasmus	0.014	0.986	0.000
E40 Kwashiorkor	0.014	0.986	0.000
E26.0 Primary hyperaldosteronism	0.014	0.986	0.000
E21.3 Hyperparathyroidism, unspecified	0.014	0.986	0.000
E24.0 Pituitary-dependent Cushing's disease	0.014	0.986	0.000
E24.2 Drug-induced Cushing's syndrome	0.013	0.986	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.013	0.987	0.000
E61.1 Iron deficiency	0.013	0.987	0.000
E24.8 Other Cushing's syndrome	0.013	0.987	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.013	0.987	0.000
E24.3 Ectopic ACTH syndrome	0.013	0.987	0.000
E24.1 Nelson's syndrome	0.013	0.987	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.012	0.987	0.000
E28.3 Primary ovarian failure	0.012	0.988	0.000
E26.9 Hyperaldosteronism, unspecified	0.012	0.988	0.000
E26.8 Other hyperaldosteronism	0.012	0.988	0.000
E26.1 Secondary hyperaldosteronism	0.012	0.988	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.988	0.012
E25.9 Adrenogenital disorder, unspecified	0.012	0.988	0.000
E25.8 Other adrenogenital disorders	0.012	0.988	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.012	0.988	0.000
E63 Other nutritional deficiencies	0.012	0.988	0.000
E56 Other vitamin deficiencies	0.012	0.988	0.000
E51 Thiamine deficiency	0.012	0.988	0.000
E50 Vitamin A deficiency	0.012	0.988	0.000
E60 Dietary zinc deficiency	0.012	0.988	0.000
E59 Dietary selenium deficiency	0.012	0.988	0.000
E58 Dietary calcium deficiency	0.012	0.988	0.000
E54 Ascorbic acid deficiency	0.012	0.988	0.000
E52 Niacin deficiency [pellagra]	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
G95.2 Cord compression, unspecified	0.012	0.988	0.000
E28.2 Polycystic ovarian syndrome	0.012	0.988	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.988	0.012
E28.9 Ovarian dysfunction, unspecified	0.011	0.988	0.000
E28.8 Other ovarian dysfunction	0.011	0.988	0.000
E28.1 Androgen excess	0.011	0.988	0.000
E28.0 Oestrogen excess	0.011	0.988	0.000
E14.9 Without complications	0.011	0.988	0.000
E22.0 Acromegaly and pituitary gigantism	0.011	0.988	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
E23 Hypofunction and other disorders of pituitary gland	0.011	0.989	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.989	0.011
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.989	0.011
K90.1 Tropical sprue	0.000	0.989	0.011
E30.9 Disorder of puberty, unspecified	0.011	0.989	0.000
E30.8 Other disorders of puberty	0.011	0.989	0.000
E30.1 Precocious puberty	0.011	0.989	0.000
E30.0 Delayed puberty	0.011	0.989	0.000
E31.9 Polyglandular dysfunction, unspecified	0.011	0.989	0.000
E31.8 Other polyglandular dysfunction	0.011	0.989	0.000
E31.1 Polyglandular hyperfunction	0.011	0.989	0.000
E31.0 Autoimmune polyglandular failure	0.011	0.989	0.000
E32.9 Disease of thymus, unspecified	0.011	0.989	0.000
E32.8 Other diseases of thymus	0.011	0.989	0.000
E32.1 Abscess of thymus	0.011	0.989	0.000
E32.0 Persistent hyperplasia of thymus	0.011	0.989	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.989	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.989	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.989	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.011	0.989	0.000
E22.8 Other hyperfunction of pituitary gland	0.011	0.989	0.000
E34.9 Endocrine disorder, unspecified	0.011	0.989	0.000
E34.8 Other specified endocrine disorders	0.011	0.989	0.000
E34.5 Androgen resistance syndrome	0.011	0.989	0.000
E34.4 Constitutional tall stature	0.011	0.989	0.000
E34.3 Short stature, not elsewhere classified	0.011	0.989	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.011	0.989	0.000
E34.1 Other hypersecretion of intestinal hormones	0.011	0.989	0.000
E65-E68 Obesity and other hyperalimentation	0.011	0.989	0.000
E20.8 Other hypoparathyroidism	0.010	0.989	0.000
E20.1 Pseudohypoparathyroidism	0.010	0.989	0.000
E20.0 Idiopathic hypoparathyroidism	0.010	0.989	0.000
E61.9 Deficiency of nutrient element, unspecified	0.010	0.989	0.000
E61.8 Deficiency of other specified nutrient elements	0.010	0.989	0.000
E61.7 Deficiency of multiple nutrient elements	0.010	0.989	0.000
E61.6 Vanadium deficiency	0.010	0.989	0.000
E61.5 Molybdenum deficiency	0.010	0.989	0.000
E61.4 Chromium deficiency	0.010	0.989	0.000
E61.3 Manganese deficiency	0.010	0.989	0.000
E61.2 Magnesium deficiency	0.010	0.989	0.000
E61.0 Copper deficiency	0.010	0.989	0.000
H36.0 Diabetic retinopathy	0.011	0.989	0.000
E34.0 Carcinoid syndrome	0.010	0.989	0.000
E22.1 Hyperprolactinaemia	0.010	0.990	0.000
E27 Other disorders of adrenal gland	0.010	0.990	0.000
E29.9 Testicular dysfunction, unspecified	0.010	0.990	0.000
E29.8 Other testicular dysfunction	0.010	0.990	0.000
E29.0 Testicular hyperfunction	0.010	0.990	0.000
E53 Deficiency of other B group vitamins	0.010	0.990	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.010	0.990	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
E44.1 Mild protein-energy malnutrition	0.010	0.990	0.000
E44.0 Moderate protein-energy malnutrition	0.010	0.990	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.010	0.990	0.000
E20.9 Hypoparathyroidism, unspecified	0.010	0.990	0.000
K90.8 Other intestinal malabsorption	0.000	0.990	0.010
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.009	0.991	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.009	0.991	0.000
E29.1 Testicular hypofunction	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
E50.9 Vitamin A deficiency, unspecified	0.009	0.991	0.000
E50.8 Other manifestations of vitamin A deficiency	0.009	0.991	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.009	0.991	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.009	0.991	0.000
E50.5 Vitamin A deficiency with night blindness	0.009	0.991	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.009	0.991	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.009	0.991	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.009	0.991	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.009	0.991	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.009	0.991	0.000
E51.9 Thiamine deficiency, unspecified	0.009	0.991	0.000
E51.8 Other manifestations of thiamine deficiency	0.009	0.991	0.000
E51.2 Wernicke's encephalopathy	0.009	0.991	0.000
E51.1 Beriberi	0.009	0.991	0.000
E56.9 Vitamin deficiency, unspecified	0.009	0.991	0.000
E56.8 Deficiency of other vitamins	0.009	0.991	0.000
E56.1 Deficiency of vitamin K	0.009	0.991	0.000
E56.0 Deficiency of vitamin E	0.009	0.991	0.000
E63.9 Nutritional deficiency, unspecified	0.009	0.991	0.000
E63.8 Other specified nutritional deficiencies	0.009	0.991	0.000
E63.1 Imbalance of constituents of food intake	0.009	0.991	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.009	0.991	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.009	0.991	0.000
E64.8 Sequelae of other nutritional deficiencies	0.009	0.991	0.000
E64.3 Sequelae of rickets	0.009	0.991	0.000
E64.2 Sequelae of vitamin C deficiency	0.009	0.991	0.000
E64.1 Sequelae of vitamin A deficiency	0.009	0.991	0.000
E64.0 Sequelae of protein-energy malnutrition	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.009	0.991	0.000
E27.2 Addisonian crisis	0.009	0.991	0.000
E55 Vitamin D deficiency	0.008	0.991	0.001
E23.7 Disorder of pituitary gland, unspecified	0.008	0.992	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.008	0.992	0.000
E23.1 Drug-induced hypopituitarism	0.008	0.992	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.008	0.992	0.000
T40.4 Other synthetic narcotics	0.008	0.992	0.000
E27.9 Disorder of adrenal gland, unspecified	0.008	0.992	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.008	0.992	0.000
M65.34 Trigger finger-Hand	0.000	0.992	0.008
E67 Other hyperalimentation	0.008	0.992	0.000
E68 Sequelae of hyperalimentation	0.008	0.992	0.000
E23.6 Other disorders of pituitary gland	0.008	0.992	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.008	0.992	0.000
S68 Traumatic amputation of wrist and hand	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
E27.5 Adrenomedullary hyperfunction	0.007	0.992	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.992	0.000
E27.0 Other adrenocortical overactivity	0.007	0.992	0.000
S22.30 Fracture of rib (closed)	0.008	0.992	0.000
G95 Other diseases of spinal cord	0.008	0.992	0.000
E65 Localised adiposity	0.008	0.992	0.000
E53.9 Vitamin B deficiency, unspecified	0.007	0.992	0.000
E53.1 Pyridoxine deficiency	0.007	0.992	0.000
E53.0 Riboflavin deficiency	0.007	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.992	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.992	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.992	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.992	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.007	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.992	0.000
T44.0 Anticholinesterase agents	0.007	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.007	0.993	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.007	0.993	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.007	0.993	0.000
K22.4 Dyskinesia of oesophagus	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
T40.6 Other and unspecified narcotics	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.007	0.993	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.007	0.993	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.007	0.993	0.000
J81 Pulmonary oedema	0.007	0.993	0.000
K22.8 Other specified diseases of oesophagus	0.007	0.993	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.007	0.993	0.000
T39.4 Antirheumatics, not elsewhere classified	0.007	0.993	0.000
T39.2 Pyrazolone derivatives	0.007	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.5 Cocaine	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.007	0.993	0.000
S22.3 Fracture of rib	0.007	0.993	0.000
S60-S69 Injuries to the wrist and hand	0.007	0.993	0.000
F41.9 Anxiety disorder, unspecified	0.006	0.994	0.000
E55.0 Rickets, active	0.006	0.994	0.001
G95.9 Disease of spinal cord, unspecified	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
F42 Obsessive-compulsive disorder	0.006	0.994	0.000
T42.1 Iminostilbenes	0.006	0.994	0.000
E67.8 Other specified hyperalimentation	0.006	0.994	0.000
E67.3 Hypervitaminosis D	0.006	0.994	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.994	0.000
E67.1 Hypercarotenaemia	0.006	0.994	0.000
E67.0 Hypervitaminosis A	0.006	0.994	0.000
S22.0 Fracture of thoracic vertebra	0.006	0.994	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.006	0.994	0.000
K22 Other diseases of oesophagus	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.006	0.994	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.006	0.994	0.000
S68.4 Traumatic amputation of hand at wrist level	0.006	0.994	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.006	0.994	0.000
K22.2 Oesophageal obstruction	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
G95.8 Other specified diseases of spinal cord	0.006	0.994	0.000
T39.0 Salicylates	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T40.2 Other opioids	0.006	0.994	0.000
Z91.5 Personal history of self-harm	0.006	0.994	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.006	0.994	0.000
E53.8 Deficiency of other specified B group vitamins	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.994	0.000
T37.5 Antiviral drugs	0.005	0.994	0.000
T37.4 Anthelminthics	0.005	0.994	0.000
T37.3 Other antiprotozoal drugs	0.005	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.994	0.000
T37.1 Antimycobacterial drugs	0.005	0.994	0.000
T37.0 Sulphonamides	0.005	0.994	0.000
T41.5 Therapeutic gases	0.005	0.994	0.000
T41.4 Anaesthetic, unspecified	0.005	0.994	0.000
T41.3 Local anaesthetics	0.005	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.994	0.000
T41.1 Intravenous anaesthetics	0.005	0.994	0.000
T41.0 Inhaled anaesthetics	0.005	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.994	0.000
T48.5 Anti-common-cold drugs	0.005	0.994	0.000
T48.4 Expectorants	0.005	0.994	0.000
T48.3 Antitussives	0.005	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.994	0.000
T48.0 Oxytocic drugs	0.005	0.994	0.000
T49.9 Topical agent, unspecified	0.005	0.994	0.000
T49.8 Other topical agents	0.005	0.994	0.000
T49.7 Dental drugs, topically applied	0.005	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.994	0.000
T49.2 Local astringents and local detergents	0.005	0.994	0.000
T49.1 Antipruritics	0.005	0.994	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.994	0.000
T45.4 Iron and its compounds	0.005	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.005	0.995	0.000
T42.3 Barbiturates	0.005	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.005	0.995	0.000
T42.0 Hydantoin derivatives	0.005	0.995	0.000
F41 Other anxiety disorders	0.005	0.995	0.000
G91 Hydrocephalus	0.005	0.995	0.000
G95.0 Syringomyelia and syringobulbia	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
S61 Open wound of wrist and hand	0.005	0.995	0.000
K22.9 Disease of oesophagus, unspecified	0.005	0.995	0.000
G90-G99 Other disorders of the nervous system	0.005	0.995	0.000
K22.0 Achalasia of cardia	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
S61.8 Open wound of other parts of wrist and hand	0.005	0.995	0.000
I45.3 Trifascicular block	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.005	0.995	0.000
H36 Retinal disorders in diseases classified elsewhere	0.005	0.995	0.000
I45.1 Other and unspecified right bundle-branch block	0.005	0.995	0.000
S22.31 Fracture of rib (open)	0.005	0.995	0.000
K04.7 Periapical abscess without sinus	0.005	0.995	0.000
F43.1 Posttraumatic stress disorder	0.005	0.995	0.000
G95.1 Vascular myelopathies	0.005	0.995	0.000
S69 Other and unspecified injuries of wrist and hand	0.005	0.995	0.000
S65 Injury of blood vessels at wrist and hand level	0.005	0.995	0.000
F43 Reaction to severe stress, and adjustment disorders	0.005	0.995	0.000
G91.2 Normal-pressure hydrocephalus	0.005	0.995	0.000
G91.9 Hydrocephalus, unspecified	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
F44 Dissociative [conversion] disorders	0.005	0.995	0.000
I45 Other conduction disorders	0.005	0.995	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.005	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
F42.8 Other obsessive-compulsive disorders	0.005	0.995	0.000
F42.2 Mixed obsessional thoughts and acts	0.005	0.995	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.005	0.995	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.005	0.995	0.000
T36.0 Penicillins	0.004	0.995	0.000
G90 Disorders of autonomic nervous system	0.005	0.995	0.000
F41.2 Mixed anxiety and depressive disorder	0.005	0.995	0.000
S22.01 Fracture of thoracic vertebra (open)	0.004	0.995	0.000
G91.1 Obstructive hydrocephalus	0.005	0.995	0.000
K22.3 Perforation of oesophagus	0.004	0.995	0.000
S67 Crushing injury of wrist and hand	0.004	0.995	0.000
S61.0 Open wound of finger(s) without damage to nail	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.995	0.000
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
I45.8 Other specified conduction disorders	0.004	0.995	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.995	0.000
S69.8 Other specified injuries of wrist and hand	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.001
I45.5 Other specified heart block	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.004	0.996	0.000
S22.8 Fracture of other parts of bony thorax	0.004	0.996	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.004	0.996	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
F43.0 Acute stress reaction	0.004	0.996	0.000
K22.5 Diverticulum of oesophagus, acquired	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.004	0.996	0.000
F48 Other neurotic disorders	0.004	0.996	0.000
F41.8 Other specified anxiety disorders	0.004	0.996	0.000
F41.3 Other mixed anxiety disorders	0.004	0.996	0.000
G91.8 Other hydrocephalus	0.004	0.996	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.004	0.996	0.000
G91.0 Communicating hydrocephalus	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
F40 Phobic anxiety disorders	0.004	0.996	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.004	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
I45.6 Preexcitation syndrome	0.004	0.996	0.000
S62 Fracture at wrist and hand level	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
M65.3 Trigger finger	0.000	0.996	0.004
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.004	0.996	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.004	0.996	0.000
G92 Toxic encephalopathy	0.004	0.996	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations