TreeWAS – Variant ID: rs6511721

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	0.987	0.013	0.000
I25 Chronic ischaemic heart disease	0.881	0.119	0.000
I25.2 Old myocardial infarction	0.865	0.135	0.000
I25.3 Aneurysm of heart	0.834	0.166	0.000
I20-I25 Ischaemic heart diseases	0.749	0.251	0.000
I24 Other acute ischaemic heart diseases	0.735	0.265	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.727	0.273	0.000
I20 Angina pectoris	0.625	0.375	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.618	0.382	0.000
I25.5 Ischaemic cardiomyopathy	0.612	0.388	0.000
I24.1 Dressler's syndrome	0.586	0.414	0.000
I25.6 Silent myocardial ischaemia	0.579	0.421	0.000
I23 Certain current complications following acute myocardial infarction	0.566	0.434	0.000
I20.0 Unstable angina	0.553	0.447	0.000
I20.9 Angina pectoris, unspecified	0.522	0.478	0.000
I20.1 Angina pectoris with documented spasm	0.502	0.498	0.000
I73.9 Peripheral vascular disease, unspecified	0.467	0.533	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.445	0.555	0.000
I23.8 Other current complications following acute myocardial infarction	0.434	0.566	0.000
I22 Subsequent myocardial infarction	0.410	0.590	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.406	0.594	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.406	0.594	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.406	0.594	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.406	0.594	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.406	0.594	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.406	0.594	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.406	0.594	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.356	0.644	0.000
I25.4 Coronary artery aneurysm	0.347	0.652	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.252	0.748	0.000
I22.8 Subsequent myocardial infarction of other sites	0.231	0.769	0.000
I21 Acute myocardial infarction	0.214	0.786	0.000
I24.8 Other forms of acute ischaemic heart disease	0.211	0.789	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.189	0.811	0.000
I21.9 Acute myocardial infarction, unspecified	0.179	0.821	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.161	0.839	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.154	0.846	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.152	0.848	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.149	0.851	0.000
I73 Other peripheral vascular diseases	0.147	0.853	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.127	0.873	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.117	0.883	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.106	0.894	0.000
I73.8 Other specified peripheral vascular diseases	0.104	0.896	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.097	0.903	0.000
I20.8 Other forms of angina pectoris	0.089	0.910	0.000
E78.3 Hyperchylomicronaemia	0.084	0.916	0.000
E78.6 Lipoprotein deficiency	0.076	0.923	0.000
E78.1 Pure hyperglyceridaemia	0.076	0.924	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.072	0.928	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.070	0.930	0.000
E78.8 Other disorders of lipoprotein metabolism	0.070	0.930	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.069	0.931	0.000
E78.5 Hyperlipidaemia, unspecified	0.067	0.933	0.000
E78.4 Other hyperlipidaemia	0.066	0.934	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.059	0.941	0.000
I78 Diseases of capillaries	0.056	0.944	0.000
Chapter IX Diseases of the circulatory system	0.055	0.945	0.000
I74 Arterial embolism and thrombosis	0.055	0.945	0.000
E78.2 Mixed hyperlipidaemia	0.054	0.946	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.053	0.947	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.051	0.949	0.000
I78.1 Naevus, nonneoplastic	0.047	0.953	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.047	0.953	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.046	0.954	0.000
I70 Atherosclerosis	0.046	0.954	0.000
I00-I02 Acute rheumatic fever	0.046	0.954	0.000
I21.4 Acute subendocardial myocardial infarction	0.044	0.956	0.000
I79.1 Aortitis in diseases classified elsewhere	0.042	0.958	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.042	0.958	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.042	0.958	0.000
I74.5 Embolism and thrombosis of iliac artery	0.042	0.958	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.040	0.959	0.000
I70.1 Atherosclerosis of renal artery	0.040	0.960	0.000
I00 Rheumatic fever without mention of heart involvement	0.039	0.961	0.000
I78.9 Disease of capillaries, unspecified	0.037	0.963	0.000
I69.3 Sequelae of cerebral infarction	0.037	0.963	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.036	0.964	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.036	0.964	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.035	0.965	0.000
I78.8 Other diseases of capillaries	0.033	0.966	0.000
I02 Rheumatic chorea	0.033	0.967	0.000
I01 Rheumatic fever with heart involvement	0.033	0.967	0.000
I70.0 Atherosclerosis of aorta	0.032	0.968	0.000
I70.9 Generalised and unspecified atherosclerosis	0.031	0.969	0.000
I74.8 Embolism and thrombosis of other arteries	0.029	0.971	0.000
I70.8 Atherosclerosis of other arteries	0.029	0.971	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.029	0.971	0.000
I77 Other disorders of arteries and arterioles	0.028	0.972	0.000
I73.0 Raynaud's syndrome	0.028	0.972	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.027	0.973	0.000
I05-I09 Chronic rheumatic heart diseases	0.027	0.973	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.025	0.975	0.000
I69 Sequelae of cerebrovascular disease	0.024	0.976	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.024	0.976	0.000
I01.8 Other acute rheumatic heart disease	0.024	0.976	0.000
I01.2 Acute rheumatic myocarditis	0.024	0.976	0.000
I01.1 Acute rheumatic endocarditis	0.024	0.976	0.000
I01.0 Acute rheumatic pericarditis	0.024	0.976	0.000
I02.9 Rheumatic chorea without heart involvement	0.024	0.976	0.000
I02.0 Rheumatic chorea with heart involvement	0.024	0.976	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.024	0.976	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.023	0.977	0.000
I08 Multiple valve diseases	0.023	0.977	0.000
O75.8 Other specified complications of labour and delivery	0.023	0.977	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.023	0.977	0.000
I60-I69 Cerebrovascular diseases	0.023	0.977	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.022	0.977	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.022	0.978	0.000
I77.2 Rupture of artery	0.022	0.978	0.000
I77.3 Arterial fibromuscular dysplasia	0.021	0.979	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.021	0.979	0.000
I06 Rheumatic aortic valve diseases	0.021	0.979	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.021	0.979	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.021	0.979	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.021	0.979	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.021	0.979	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.021	0.979	0.000
I72 Other aneurysm	0.021	0.979	0.000
I77.5 Necrosis of artery	0.020	0.979	0.000
I77.4 Coeliac artery compression syndrome	0.020	0.979	0.000
I77.1 Stricture of artery	0.020	0.980	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.020	0.980	0.000
O14.9 Preeclampsia, unspecified	0.020	0.980	0.000
I08.9 Multiple valve disease, unspecified	0.019	0.981	0.000
I61 Intracerebral haemorrhage	0.019	0.981	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.018	0.982	0.000
O75.0 Maternal distress during labour and delivery	0.018	0.982	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.018	0.982	0.000
S70 Superficial injury of hip and thigh	0.000	0.982	0.018
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.982	0.018
S71.1 Open wound of thigh	0.000	0.982	0.018
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.017	0.982	0.000
O14.0 Moderate preeclampsia	0.017	0.983	0.000
S70.1 Contusion of thigh	0.000	0.983	0.017
I06.2 Rheumatic aortic stenosis with insufficiency	0.017	0.983	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.017	0.983	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.017	0.983	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.017	0.983	0.000
I09 Other rheumatic heart diseases	0.017	0.983	0.000
I72.2 Aneurysm of renal artery	0.017	0.983	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.016	0.983	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.016	0.983	0.000
O75.9 Complication of labour and delivery, unspecified	0.016	0.984	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.015	0.984	0.001
O75.5 Delayed delivery after artificial rupture of membranes	0.016	0.984	0.000
I77.0 Arteriovenous fistula, acquired	0.016	0.984	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.016	0.984	0.000
I72.9 Aneurysm of unspecified site	0.016	0.984	0.000
S71 Open wound of hip and thigh	0.000	0.984	0.016
I60 Subarachnoid haemorrhage	0.016	0.984	0.000
I51.9 Heart disease, unspecified	0.016	0.984	0.000
I08.8 Other multiple valve diseases	0.016	0.984	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.016	0.984	0.000
S70-S79 Injuries to the hip and thigh	0.000	0.984	0.016
I06.8 Other rheumatic aortic valve diseases	0.015	0.985	0.000
I77.8 Other specified disorders of arteries and arterioles	0.015	0.985	0.000
M21.0 Valgus deformity, not elsewhere classified	0.015	0.985	0.000
O75.4 Other complications of obstetric surgery and procedures	0.015	0.985	0.000
O75.1 Shock during or following labour and delivery	0.015	0.985	0.000
O75.3 Other infection during labour	0.015	0.985	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.015	0.985	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.015	0.985	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.985	0.015
I71 Aortic aneurysm and dissection	0.015	0.985	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.015	0.985	0.000
I72.4 Aneurysm of artery of lower extremity	0.015	0.985	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.015	0.985	0.000
I06.0 Rheumatic aortic stenosis	0.015	0.985	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.015	0.985	0.000
S72 Fracture of femur	0.000	0.986	0.014
I06.1 Rheumatic aortic insufficiency	0.014	0.986	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.014	0.986	0.000
I72.1 Aneurysm of artery of upper extremity	0.014	0.986	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.014	0.986	0.000
R49.0 Dysphonia	0.014	0.986	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.014	0.986	0.000
I07 Rheumatic tricuspid valve diseases	0.013	0.987	0.000
I65.1 Occlusion and stenosis of basilar artery	0.013	0.987	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.013	0.987	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.987	0.013
S72.0 Fracture of neck of femur	0.000	0.987	0.013
I08.2 Disorders of both aortic and tricuspid valves	0.013	0.987	0.000
I62 Other nontraumatic intracranial haemorrhage	0.013	0.987	0.000
I61.8 Other intracerebral haemorrhage	0.012	0.987	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.012	0.987	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.012	0.988	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.012	0.988	0.000
I09.8 Other specified rheumatic heart diseases	0.012	0.988	0.000
I09.2 Chronic rheumatic pericarditis	0.012	0.988	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.012	0.988	0.000
I09.0 Rheumatic myocarditis	0.012	0.988	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.012	0.988	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.012	0.988	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I68.0 Cerebral amyloid angiopathy	0.012	0.988	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.988	0.012
I72.0 Aneurysm of carotid artery	0.012	0.988	0.000
S72.3 Fracture of shaft of femur	0.000	0.988	0.012
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.988	0.012
S71.7 Multiple open wounds of of hip and thigh	0.000	0.988	0.012
I60.5 Subarachnoid haemorrhage from vertebral artery	0.012	0.988	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.012	0.988	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.012	0.988	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.012	0.988	0.000
S72.8 Fractures of other parts of femur	0.000	0.988	0.012
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.012	0.988	0.000
O14.2 HELLP syndrome	0.011	0.988	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.988	0.012
S78 Traumatic amputation of hip and thigh	0.000	0.988	0.011
S77 Crushing injury of hip and thigh	0.000	0.988	0.011
S74 Injury of nerves at hip and thigh level	0.000	0.988	0.011
S72.9 Fracture of femur, part unspecified	0.000	0.989	0.011
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.011	0.989	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.011	0.989	0.000
S71.0 Open wound of hip	0.000	0.989	0.011
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.011	0.989	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.011	0.989	0.000
I28 Other diseases of pulmonary vessels	0.011	0.989	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.011	0.989	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.011	0.989	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.011	0.989	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.000	0.989	0.011
I71.8 Aortic aneurysm of unspecified site, ruptured	0.011	0.989	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.011	0.989	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.011	0.989	0.000
I60.8 Other subarachnoid haemorrhage	0.011	0.989	0.000
T79.6 Traumatic ischaemia of muscle	0.011	0.989	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.011	0.989	0.000
S75 Injury of blood vessels at hip and thigh level	0.000	0.989	0.011
T79 Certain early complications of trauma, not elsewhere classified	0.011	0.989	0.000
M21.27 Flexion deformity (Ankle and foot)	0.011	0.989	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.010	0.989	0.000
S72.7 Multiple fractures of femur	0.000	0.989	0.010
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.000	0.989	0.011
T79.3 Post-traumatic wound infection, not elsewhere classified	0.010	0.990	0.000
S72.1 Pertrochanteric fracture	0.000	0.990	0.010
S72.30 Fracture of shaft of femur (closed)	0.000	0.990	0.010
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.010	0.990	0.000
I71.0 Dissection of aorta [any part]	0.010	0.990	0.000
S72.4 Fracture of lower end of femur	0.000	0.990	0.010
S70.0 Contusion of hip	0.000	0.990	0.010
T79.8 Other early complications of trauma	0.010	0.990	0.000
M21.2 Flexion deformity	0.010	0.990	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.990	0.010
I09.9 Rheumatic heart disease, unspecified	0.009	0.990	0.000
I07.9 Tricuspid valve disease, unspecified	0.010	0.990	0.000
I07.8 Other tricuspid valve diseases	0.010	0.990	0.000
I07.2 Tricuspid stenosis with insufficiency	0.010	0.990	0.000
I07.0 Tricuspid stenosis	0.010	0.990	0.000
I67 Other cerebrovascular diseases	0.010	0.990	0.000
I67.8 Other specified cerebrovascular diseases	0.010	0.990	0.000
S76.1 Injury of quadriceps muscle and tendon	0.000	0.990	0.009
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.000	0.990	0.009
S76.2 Injury of adductor muscle and tendon of thigh	0.000	0.990	0.009
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.009	0.991	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.991	0.009
S79 Other and unspecified injuries of hip and thigh	0.000	0.991	0.009
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.991	0.009
G96.0 Cerebrospinal fluid leak	0.000	0.991	0.009
I72.3 Aneurysm of iliac artery	0.009	0.991	0.000
S72.2 Subtrochanteric fracture	0.000	0.991	0.009
M21 Other acquired deformities of limbs	0.009	0.991	0.000
T79.5 Traumatic anuria	0.009	0.991	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.008	0.991	0.001
S72.31 Fracture of shaft of femur (open)	0.000	0.991	0.009
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.009	0.991	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.991	0.009
S76.0 Injury of muscle and tendon of hip	0.000	0.991	0.008
I26 Pulmonary embolism	0.009	0.991	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.000	0.991	0.008
S74.8 Injury of other nerves at hip and thigh level	0.000	0.991	0.008
S74.7 Injury of multiple nerves at hip and thigh level	0.000	0.991	0.008
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.000	0.991	0.008
S74.1 Injury of femoral nerve at hip and thigh level	0.000	0.991	0.008
S74.0 Injury of sciatic nerve at hip and thigh level	0.000	0.991	0.008
S77.2 Crushing injury of hip with thigh	0.000	0.991	0.008
S77.1 Crushing injury of thigh	0.000	0.991	0.008
S77.0 Crushing injury of hip	0.000	0.991	0.008
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.000	0.991	0.008
S78.1 Traumatic amputation at level between hip and knee	0.000	0.991	0.008
S78.0 Traumatic amputation at hip joint	0.000	0.991	0.008
S72.91 Fracture of femur, part unspecified (open)	0.000	0.992	0.008
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.992	0.008
M21.26 Flexion deformity (Lower leg)	0.008	0.992	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.992	0.008
I28.9 Disease of pulmonary vessels, unspecified	0.008	0.992	0.000
I28.1 Aneurysm of pulmonary artery	0.008	0.992	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.008	0.992	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.992	0.008
I62.1 Nontraumatic extradural haemorrhage	0.008	0.992	0.000
I67.1 Cerebral aneurysm, nonruptured	0.008	0.992	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.992	0.008
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.000	0.992	0.008
S75.8 Injury of other blood vessels at hip and thigh level	0.000	0.992	0.008
S75.7 Injury of multiple blood vessels at hip and thigh level	0.000	0.992	0.008
S75.2 Injury of greater saphenous vein at hip and thigh level	0.000	0.992	0.008
S75.1 Injury of femoral vein at hip and thigh level	0.000	0.992	0.008
T79.9 Unspecified early complication of trauma	0.008	0.992	0.000
T79.4 Traumatic shock	0.008	0.992	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.008	0.992	0.000
T79.1 Fat embolism (traumatic)	0.008	0.992	0.000
T79.0 Air embolism (traumatic)	0.008	0.992	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.992	0.008
S72.70 Multiple fractures of femur (closed)	0.000	0.992	0.008
I10-I15 Hypertensive diseases	0.008	0.992	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.992	0.008
M21.22 Flexion deformity (Upper arm)	0.008	0.992	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.008	0.992	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.992	0.007
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.008	0.992	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.007	0.992	0.000
I28.8 Other specified diseases of pulmonary vessels	0.007	0.992	0.000
M21.8 Other specified acquired deformities of limbs	0.007	0.992	0.000
M21.29 Flexion deformity (Site unspecified)	0.007	0.993	0.000
M21.28 Flexion deformity (Other)	0.007	0.993	0.000
M21.23 Flexion deformity (Forearm)	0.007	0.993	0.000
M21.21 Flexion deformity (Shoulder region)	0.007	0.993	0.000
M21.20 Flexion deformity (Multiple sites)	0.007	0.993	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.007	0.993	0.000
M21.24 Flexion deformity (Hand)	0.007	0.993	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.007	0.993	0.000
I67.5 Moyamoya disease	0.007	0.993	0.000
I67.4 Hypertensive encephalopathy	0.007	0.993	0.000
I67.3 Progressive vascular leukoencephalopathy	0.007	0.993	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.000	0.993	0.007
S72.10 Pertrochanteric fracture (closed)	0.000	0.993	0.007
S75.0 Injury of femoral artery	0.000	0.993	0.007
M21.25 Flexion deformity (Pelvic region and thigh)	0.007	0.993	0.000
S79.7 Multiple injuries of hip and thigh	0.000	0.993	0.007
O14.1 Severe preeclampsia	0.007	0.993	0.000
C34.0 Main bronchus	0.000	0.993	0.007
S79.8 Other specified injuries of hip and thigh	0.000	0.993	0.007
I69.1 Sequelae of intracerebral haemorrhage	0.006	0.993	0.001
S72.21 Subtrochanteric fracture (open)	0.000	0.993	0.007
I08.0 Disorders of both mitral and aortic valves	0.007	0.993	0.000
M21.9 Acquired deformity of limb, unspecified	0.007	0.993	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.993	0.007
I66.8 Occlusion and stenosis of other cerebral artery	0.006	0.993	0.001
I66.2 Occlusion and stenosis of posterior cerebral artery	0.006	0.993	0.001
I66.1 Occlusion and stenosis of anterior cerebral artery	0.006	0.993	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.007	0.993	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.006	0.993	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.007	0.993	0.000
C16.0 Cardia	0.007	0.993	0.000
T79.7 Traumatic subcutaneous emphysema	0.006	0.993	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.006	0.993	0.000
M21.3 Wrist or foot drop (acquired)	0.006	0.994	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.994	0.006
S72.40 Fracture of lower end of femur (closed)	0.000	0.994	0.006
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.006	0.994	0.000
I51 Complications and ill-defined descriptions of heart disease	0.006	0.994	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.006	0.994	0.000
M21.7 Unequal limb length (acquired)	0.006	0.994	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.006	0.994	0.001
I72.8 Aneurysm of other specified arteries	0.005	0.994	0.001
Z51.2 Other chemotherapy	0.000	0.994	0.006
I97.2 Postmastectomy lymphoedema syndrome	0.006	0.994	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.005	0.994	0.001
I13 Hypertensive heart and renal disease	0.006	0.994	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.006	0.994	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.006	0.994	0.000
M21.4 Flat foot [pes planus] (acquired)	0.006	0.994	0.000
G12.2 Motor neuron disease	0.006	0.994	0.000
I99 Other and unspecified disorders of circulatory system	0.006	0.994	0.000
I51.6 Cardiovascular disease, unspecified	0.006	0.994	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.006	0.994	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.006	0.994	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.006	0.994	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.006	0.994	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.006	0.994	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.006	0.994	0.000
N82.3 Fistula of vagina to large intestine	0.000	0.994	0.006
M21.1 Varus deformity, not elsewhere classified	0.006	0.994	0.000
S73.1 Sprain and strain of hip	0.000	0.994	0.005
I51.5 Myocardial degeneration	0.005	0.995	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.005	0.995	0.001
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.005	0.995	0.000
I51.4 Myocarditis, unspecified	0.005	0.995	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.995	0.005
S72.20 Subtrochanteric fracture (closed)	0.000	0.995	0.005
I15 Secondary hypertension	0.005	0.995	0.000
I97.0 Postcardiotomy syndrome	0.005	0.995	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.995	0.001
C49.1 Connective and soft tissue of upper limb, including shoulder	0.005	0.995	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.005	0.995	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.005	0.995	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.005	0.995	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.005	0.995	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.005	0.995	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.005	0.995	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.005	0.995	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.005	0.995	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.005	0.995	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.005	0.995	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.995	0.005
M21.76 Unequal limb length (acquired) (Lower leg)	0.005	0.995	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.004	0.995	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.005	0.995	0.000
N82.4 Other female intestinal-genital tract fistulae	0.000	0.995	0.005
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.005	0.995	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.005	0.995	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.005	0.995	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.005	0.995	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.005	0.995	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.005	0.995	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.005	0.995	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.005	0.995	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.005	0.995	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.995	0.005
M21.39 Wrist or foot drop (acquired)-Site unspec	0.005	0.995	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.005	0.995	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.005	0.995	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.005	0.995	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.005	0.995	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.005	0.995	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.005	0.995	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.005	0.995	0.000
S79.9 Unspecified injury of hip and thigh	0.000	0.995	0.005
I51.2 Rupture of papillary muscle, not elsewhere classified	0.005	0.995	0.000
I11 Hypertensive heart disease	0.005	0.995	0.000
N82 Fistulae involving female genital tract	0.000	0.995	0.005
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.005	0.995	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.005	0.995	0.000
M21.78 Unequal limb length (acquired)-Other	0.005	0.995	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.005	0.995	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.005	0.995	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.005	0.995	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.005	0.995	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.005	0.995	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.005	0.995	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.005	0.995	0.000
I77.6 Arteritis, unspecified	0.003	0.995	0.002
R49 Voice disturbances	0.005	0.995	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.004	0.995	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.004	0.995	0.000
I97.1 Other functional disturbances following cardiac surgery	0.004	0.995	0.000
S73.0 Dislocation of hip	0.000	0.995	0.004
I05 Rheumatic mitral valve diseases	0.004	0.995	0.001
I13.9 Hypertensive heart and renal disease, unspecified	0.004	0.995	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.004	0.995	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.004	0.995	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.004	0.995	0.000
T79-T79 Certain early complications of trauma	0.004	0.995	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.004	0.995	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.004	0.995	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.004	0.995	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.004	0.995	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.004	0.995	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.004	0.995	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.004	0.995	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.004	0.995	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.004	0.995	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.004	0.995	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.004	0.996	0.000
I15.0 Renovascular hypertension	0.004	0.996	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.004	0.996	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.004	0.996	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.004	0.996	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
N82.5 Female genital tract-skin fistulae	0.000	0.996	0.004
I15.9 Seconday hypertension, unspecified	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
I15.8 Other secondary hypertension	0.004	0.996	0.000
J92.9 Pleural plaque without asbestos	0.004	0.996	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.996	0.004
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.996	0.001
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.996	0.001
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.996	0.001
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.996	0.001
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.996	0.001
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.996	0.001
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.996	0.001
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.996	0.001
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.996	0.001
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.004	0.996	0.000
C49.5 Connective and soft tissue of pelvis	0.004	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.996	0.004
I15.2 Hypertension secondary to endocrine disorders	0.004	0.996	0.000
T93 Sequelae of injuries of lower limb	0.000	0.996	0.004
N82.0 Vesicovaginal fistula	0.000	0.996	0.004
N82.9 Female genital tract fistula, unspecified	0.000	0.996	0.004
I07.1 Tricuspid insufficiency	0.003	0.996	0.000
N82.8 Other female genital tract fistulae	0.000	0.996	0.004
N82.2 Fistula of vagina to small intestine	0.000	0.996	0.004
T93.1 Sequelae of fracture of femur	0.000	0.996	0.004
R49.2 Hypernasality and hyponasality	0.003	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations