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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6679677
log Bayes Factor = 148.434
Chromosome 1   position 114,303,808  (GRCh37) Explore rs6679677 on Ensembl!
Variant rs6679677 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
D51 Vitamin B12 deficiency anaemia
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
M05 Seropositive rheumatoid arthritis
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
J30-J39 Other diseases of upper respiratory tract
0.997 0.003 0.000
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.996 0.004 0.000
I10 Essential (primary) hypertension
0.996 0.004 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
I51 Complications and ill-defined descriptions of heart disease
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
I21.9 Acute myocardial infarction, unspecified
0.994 0.006 0.000
E89.0 Postprocedural hypothyroidism
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
H36 Retinal disorders in diseases classified elsewhere
0.991 0.009 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.991 0.009 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.989 0.011 0.000
H36.0 Diabetic retinopathy
0.987 0.013 0.000
I25.1 Atherosclerotic heart disease
0.987 0.013 0.000
D60-D64 Aplastic and other anaemias
0.986 0.014 0.000
I51.7 Cardiomegaly
0.986 0.014 0.000
E16 Other disorders of pancreatic internal secretion
0.985 0.015 0.000
I20 Angina pectoris
0.984 0.016 0.000
D64 Other anaemias
0.983 0.017 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.982 0.018 0.000
E11.9 Without complications
0.981 0.019 0.000
D64.9 Anaemia, unspecified
0.981 0.019 0.000
E16.2 Hypoglycaemia, unspecified
0.981 0.019 0.000
I77 Other disorders of arteries and arterioles
0.980 0.020 0.000
J40-J47 Chronic lower respiratory diseases
0.978 0.022 0.000
I20.9 Angina pectoris, unspecified
0.977 0.023 0.000
M07 Psoriatic and enteropathic arthropathies
0.974 0.026 0.000
J33 Nasal polyp
0.973 0.027 0.000
I51.9 Heart disease, unspecified
0.970 0.030 0.000
E10.5 With peripheral circulatory complications
0.968 0.032 0.000
J18 Pneumonia, organism unspecified
0.967 0.033 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.967 0.033 0.000
H35 Other retinal disorders
0.967 0.033 0.000
Z88.0 Personal history of allergy to penicillin
0.963 0.037 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.962 0.038 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.962 0.038 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.959 0.041 0.000
M07.3 Other psoriatic arthropathies
0.955 0.045 0.000
E11.5 With peripheral circulatory complications
0.955 0.045 0.000
D80-D89 Certain disorders involving the immune mechanism
0.955 0.045 0.000
H35.3 Degeneration of macula and posterior pole
0.954 0.046 0.000
M70-M79 Other soft tissue disorders
0.952 0.048 0.000
M06.3 Rheumatoid nodule
0.950 0.050 0.000
E05.9 Thyrotoxicosis, unspecified
0.949 0.051 0.000
J18.9 Pneumonia, unspecified
0.949 0.051 0.000
E10.4 With neurological complications
0.948 0.052 0.000
J33.9 Nasal polyp, unspecified
0.947 0.053 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.945 0.055 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.942 0.058 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.938 0.062 0.000
Z88.6 Personal history of allergy to analgesic agent
0.938 0.062 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.938 0.062 0.000
M75 Shoulder lesions
0.938 0.062 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.936 0.064 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.936 0.064 0.000
Z88.2 Personal history of allergy to sulphonamides
0.936 0.064 0.000
J34 Other disorders of nose and nasal sinuses
0.933 0.067 0.000
I77.6 Arteritis, unspecified
0.931 0.069 0.000
E10.8 With unspecified complications
0.929 0.071 0.000
Chapter I Certain infectious and parasitic diseases
0.928 0.072 0.000
J32 Chronic sinusitis
0.926 0.074 0.000
M06.0 Seronegative rheumatoid arthritis
0.925 0.075 0.000
J00-J06 Acute upper respiratory infections
0.924 0.076 0.000
M75.0 Adhesive capsulitis of shoulder
0.923 0.077 0.000
I49 Other cardiac arrhythmias
0.922 0.078 0.000
B35-B49 Mycoses
0.919 0.081 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.918 0.082 0.000
I22 Subsequent myocardial infarction
0.917 0.083 0.000
I74 Arterial embolism and thrombosis
0.917 0.083 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.915 0.085 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.915 0.085 0.000
M75.5 Bursitis of shoulder
0.915 0.085 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.913 0.087 0.000
M86-M90 Other osteopathies
0.913 0.087 0.000
J32.9 Chronic sinusitis, unspecified
0.913 0.087 0.000
E87.6 Hypokalaemia
0.911 0.089 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.904 0.096 0.000
E10.2 With renal complications
0.900 0.100 0.000
M06.34 Rheumatoid nodule (Hand)
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.897 0.103 0.000
I35 Nonrheumatic aortic valve disorders
0.897 0.103 0.000
E11.1 With ketoacidosis
0.896 0.104 0.000
J47 Bronchiectasis
0.895 0.105 0.000
M12 Other specific arthropathies
0.894 0.106 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.889 0.111 0.000
I49.0 Ventricular fibrillation and flutter
0.888 0.112 0.000
D86 Sarcoidosis
0.888 0.112 0.000
I34 Nonrheumatic mitral valve disorders
0.888 0.112 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.887 0.113 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.884 0.116 0.000
I77.1 Stricture of artery
0.881 0.119 0.000
Chapter XX External causes of morbidity and mortality
0.880 0.120 0.000
H33 Retinal detachments and breaks
0.879 0.121 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.879 0.121 0.000
B37 Candidiasis
0.876 0.124 0.000
E06 Thyroiditis
0.874 0.126 0.000
E20-E35 Disorders of other endocrine glands
0.873 0.127 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.872 0.128 0.000
E10.6 With other specified complications
0.872 0.128 0.000
E78.0 Pure hypercholesterolaemia
0.871 0.129 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.871 0.129 0.000
J02 Acute pharyngitis
0.870 0.130 0.000
I49.3 Ventricular premature depolarisation
0.864 0.136 0.000
I73 Other peripheral vascular diseases
0.862 0.138 0.000
D55-D59 Haemolytic anaemias
0.859 0.141 0.000
H20 Iridocyclitis
0.857 0.143 0.000
J39 Other diseases of upper respiratory tract
0.856 0.144 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.855 0.145 0.000
I15 Secondary hypertension
0.855 0.145 0.000
J45 Asthma
0.852 0.148 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
J17 Pneumonia in diseases classified elsewhere
0.847 0.153 0.000
H31 Other disorders of choroid
0.845 0.154 0.000
J35 Chronic diseases of tonsils and adenoids
0.842 0.158 0.000
J36 Peritonsillar abscess
0.840 0.160 0.000
J15.9 Bacterial pneumonia, unspecified
0.839 0.161 0.000
B37.3 Candidiasis of vulva and vagina
0.837 0.163 0.000
J40 Bronchitis, not specified as acute or chronic
0.835 0.165 0.000
E86 Volume depletion
0.834 0.166 0.000
I21.4 Acute subendocardial myocardial infarction
0.833 0.167 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.833 0.167 0.000
B37.8 Candidiasis of other sites
0.832 0.168 0.000
J02.9 Acute pharyngitis, unspecified
0.831 0.169 0.000
B44 Aspergillosis
0.831 0.169 0.000
E89.3 Postprocedural hypopituitarism
0.830 0.170 0.000
M76 Enthesopathies of lower limb, excluding foot
0.828 0.172 0.000
E14 Unspecified diabetes mellitus
0.826 0.174 0.000
M71 Other bursopathies
0.825 0.175 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.823 0.177 0.000
J20-J22 Other acute lower respiratory infections
0.823 0.177 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.822 0.178 0.000
H34 Retinal vascular occlusions
0.821 0.179 0.000
W20-W49 Exposure to inanimate mechanical forces
0.820 0.180 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.819 0.181 0.000
I51.4 Myocarditis, unspecified
0.819 0.181 0.000
D84 Other immunodeficiencies
0.817 0.183 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.817 0.183 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.816 0.184 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.815 0.185 0.000
E06.3 Autoimmune thyroiditis
0.814 0.186 0.000
I25.5 Ischaemic cardiomyopathy
0.814 0.186 0.000
J14 Pneumonia due to Haemophilus influenzae
0.813 0.187 0.000
J04 Acute laryngitis and tracheitis
0.812 0.188 0.000
M86 Osteomyelitis
0.811 0.189 0.000
D52 Folate deficiency anaemia
0.811 0.189 0.000
H60-H62 Diseases of external ear
0.809 0.191 0.000
I73.9 Peripheral vascular disease, unspecified
0.808 0.192 0.000
M60-M63 Disorders of muscles
0.806 0.194 0.000
J43 Emphysema
0.803 0.197 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.801 0.199 0.000
I20.0 Unstable angina
0.800 0.200 0.000
H30 Chorioretinal inflammation
0.795 0.205 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.795 0.205 0.000
E10.0 With coma
0.794 0.206 0.000
I51.0 Cardiac septal defect, acquired
0.792 0.208 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.792 0.208 0.000
A15-A19 Tuberculosis
0.790 0.210 0.000
J45.9 Asthma, unspecified
0.789 0.211 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.789 0.211 0.000
E78.8 Other disorders of lipoprotein metabolism
0.789 0.211 0.000
E03.8 Other specified hypothyroidism
0.789 0.211 0.000
J11 Influenza, virus not identified
0.788 0.212 0.000
B35 Dermatophytosis
0.786 0.214 0.000
I51.8 Other ill-defined heart diseases
0.786 0.214 0.000
J33.8 Other polyp of sinus
0.785 0.215 0.000
E78.1 Pure hyperglyceridaemia
0.785 0.215 0.000
H60 Otitis externa
0.784 0.216 0.000
Chapter XXII Codes for special purposes
0.783 0.217 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.782 0.218 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.782 0.218 0.000
H31.8 Other specified disorders of choroid
0.781 0.219 0.000
E05.8 Other thyrotoxicosis
0.781 0.219 0.000
H35.0 Background retinopathy and retinal vascular changes
0.781 0.219 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.781 0.219 0.000
M12.2 Villonodular synovitis (pigmented)
0.780 0.220 0.000
I34.1 Mitral (valve) prolapse
0.778 0.222 0.000
D86.3 Sarcoidosis of skin
0.778 0.222 0.000
H33.2 Serous retinal detachment
0.778 0.222 0.000
I70 Atherosclerosis
0.777 0.223 0.000
Chapter VI Diseases of the nervous system
0.776 0.224 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.776 0.224 0.000
I46 Cardiac arrest
0.775 0.225 0.000
H40-H42 Glaucoma
0.775 0.225 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.773 0.227 0.000
H20.0 Acute and subacute iridocyclitis
0.773 0.227 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.771 0.229 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.770 0.230 0.000
J15.2 Pneumonia due to staphylococcus
0.768 0.232 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.767 0.233 0.000
H60.9 Otitis externa, unspecified
0.766 0.234 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.766 0.234 0.000
E26 Hyperaldosteronism
0.764 0.236 0.000
E11.8 With unspecified complications
0.762 0.238 0.000
B25-B34 Other viral diseases
0.760 0.240 0.000
E11.3 With ophthalmic complications
0.759 0.241 0.000
I25.3 Aneurysm of heart
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.756 0.243 0.000
E40-E46 Malnutrition
0.756 0.244 0.000
I40 Acute myocarditis
0.756 0.244 0.000
M06.4 Inflammatory polyarthropathy
0.756 0.244 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.756 0.244 0.000
I49.1 Atrial premature depolarisation
0.755 0.245 0.000
J00 Acute nasopharyngitis [common cold]
0.753 0.247 0.000
E11.0 With coma
0.753 0.247 0.000
I15.1 Hypertension secondary to other renal disorders
0.752 0.248 0.000
I77.8 Other specified disorders of arteries and arterioles
0.752 0.248 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.751 0.249 0.000
J18.0 Bronchopneumonia, unspecified
0.751 0.249 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.749 0.250 0.000
J18.8 Other pneumonia, organism unspecified
0.749 0.251 0.000
H20.9 Iridocyclitis, unspecified
0.748 0.252 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.745 0.254 0.000
D86.0 Sarcoidosis of lung
0.745 0.255 0.000
E11.2 With renal complications
0.744 0.256 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.744 0.256 0.000
G70-G73 Diseases of myoneural junction and muscle
0.743 0.257 0.000
I77.0 Arteriovenous fistula, acquired
0.743 0.257 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.743 0.257 0.000
D83 Common variable immunodeficiency
0.742 0.258 0.000
E14.3 With ophthalmic complications
0.738 0.262 0.000
E27 Other disorders of adrenal gland
0.735 0.265 0.000
J35.0 Chronic tonsillitis
0.734 0.266 0.000
H33.0 Retinal detachment with retinal break
0.733 0.267 0.000
J04.0 Acute laryngitis
0.733 0.267 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.732 0.268 0.000
H35.6 Retinal haemorrhage
0.731 0.269 0.000
I30 Acute pericarditis
0.730 0.270 0.000
J17.2 Pneumonia in mycoses
0.729 0.271 0.000
H33.4 Traction detachment of retina
0.729 0.271 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.729 0.271 0.000
B44.9 Aspergillosis, unspecified
0.727 0.272 0.000
M12.3 Palindromic rheumatism
0.727 0.273 0.000
D53 Other nutritional anaemias
0.727 0.273 0.000
J15.1 Pneumonia due to Pseudomonas
0.726 0.274 0.000
M90 Osteopathies in diseases classified elsewhere
0.726 0.274 0.000
A80-A89 Viral infections of the central nervous system
0.726 0.274 0.000
D56 Thalassaemia
0.724 0.276 0.000
H20.1 Chronic iridocyclitis
0.724 0.276 0.000
H35.7 Separation of retinal layers
0.723 0.277 0.000
J32.2 Chronic ethmoidal sinusitis
0.723 0.277 0.000
M86.9 Osteomyelitis, unspecified
0.721 0.279 0.000
M10 Gout
0.720 0.279 0.000
E88 Other metabolic disorders
0.720 0.280 0.000
J44 Other chronic obstructive pulmonary disease
0.719 0.281 0.000
J84 Other interstitial pulmonary diseases
0.719 0.281 0.000
G70 Myasthenia gravis and other myoneural disorders
0.719 0.281 0.000
D84.9 Immunodeficiency, unspecified
0.718 0.282 0.000
E10.7 With multiple complications
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.717 0.283 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.717 0.283 0.000
D51.2 Transcobalamin II deficiency
0.717 0.283 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.717 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.717 0.283 0.000
J12 Viral pneumonia, not elsewhere classified
0.717 0.283 0.000
J09 Influenza due to certain identified influenza virus
0.717 0.283 0.000
Y57 Other and unspecified drugs and medicaments
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.283 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
M05.8 Other seropositive rheumatoid arthritis
0.715 0.285 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.715 0.285 0.000
M05.2 Rheumatoid vasculitis
0.715 0.285 0.000
M05.1 Rheumatoid lung disease
0.715 0.285 0.000
M05.0 Felty's syndrome
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.285 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.714 0.286 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.714 0.286 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.714 0.286 0.000
E89.5 Postprocedural testicular hypofunction
0.714 0.286 0.000
E89.4 Postprocedural ovarian failure
0.714 0.286 0.000
E89.1 Postprocedural hypoinsulinaemia
0.714 0.286 0.000
B49 Unspecified mycosis
0.714 0.286 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.714 0.286 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.714 0.286 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.714 0.286 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.714 0.286 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.714 0.286 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.714 0.286 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.714 0.286 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I51.5 Myocardial degeneration
0.714 0.286 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.714 0.286 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.714 0.286 0.000
M76.6 Achilles tendinitis
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.711 0.289 0.000
E15 Nondiabetic hypoglycaemic coma
0.710 0.289 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.710 0.290 0.000
M72 Fibroblastic disorders
0.710 0.290 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.709 0.291 0.000
J35.1 Hypertrophy of tonsils
0.709 0.291 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.709 0.291 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.292 0.000
Q21 Congenital malformations of cardiac septa
0.708 0.292 0.000
G62 Other polyneuropathies
0.708 0.292 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.707 0.292 0.000
J39.8 Other specified diseases of upper respiratory tract
0.707 0.293 0.000
J33.0 Polyp of nasal cavity
0.707 0.293 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.707 0.293 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.706 0.294 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.706 0.294 0.000
E16.4 Abnormal secretion of gastrin
0.706 0.294 0.000
E16.3 Increased secretion of glucagon
0.706 0.294 0.000
M88 Paget's disease of bone [osteitis deformans]
0.705 0.295 0.000
D64.8 Other specified anaemias
0.705 0.295 0.000
D64.4 Congenital dyserythropoietic anaemia
0.705 0.295 0.000
D64.3 Other sideroblastic anaemias
0.705 0.295 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.705 0.295 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.705 0.295 0.000
D64.0 Hereditary sideroblastic anaemia
0.705 0.295 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.704 0.296 0.000
I77.5 Necrosis of artery
0.703 0.297 0.000
I77.4 Coeliac artery compression syndrome
0.703 0.297 0.000
I77.3 Arterial fibromuscular dysplasia
0.703 0.297 0.000
I77.2 Rupture of artery
0.703 0.297 0.000
J41 Simple and mucopurulent chronic bronchitis
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.700 0.300 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.700 0.300 0.000
M60 Myositis
0.699 0.300 0.000
E13 Other specified diabetes mellitus
0.699 0.301 0.000
H35.9 Retinal disorder, unspecified
0.699 0.301 0.000
Chapter V Mental and behavioural disorders
0.699 0.301 0.000
H35.8 Other specified retinal disorders
0.699 0.301 0.000
I35.1 Aortic (valve) insufficiency
0.699 0.301 0.000
M07.6 Other enteropathic arthropathies
0.698 0.302 0.000
M07.5 Arthropathy in ulcerative colitis
0.698 0.302 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.698 0.302 0.000
M07.2 Psoriatic spondylitis
0.698 0.302 0.000
M07.1 Arthritis mutilans
0.698 0.302 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
J33.1 Polypoid sinus degeneration
0.698 0.302 0.000
M75.2 Bicipital tendinitis
0.698 0.302 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
W29 Contact with other powered hand tools and household machinery
0.696 0.304 0.000
G70.0 Myasthenia gravis
0.695 0.305 0.000
J18.2 Hypostatic pneumonia, unspecified
0.694 0.306 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
H35.1 Retinopathy of prematurity
0.693 0.307 0.000
E27.1 Primary adrenocortical insufficiency
0.692 0.308 0.000
I34.0 Mitral (valve) insufficiency
0.691 0.309 0.000
Y00-Y09 Assault
0.691 0.309 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.690 0.309 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
E16.1 Other hypoglycaemia
0.690 0.310 0.000
E05.5 Thyroid crisis or storm
0.690 0.310 0.000
E05.4 Thyrotoxicosis factitia
0.690 0.310 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.690 0.310 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.690 0.310 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.690 0.310 0.000
Q28 Other congenital malformations of circulatory system
0.689 0.311 0.000
J39.2 Other diseases of pharynx
0.688 0.312 0.000
B44.1 Other pulmonary aspergillosis
0.687 0.313 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
J46 Status asthmaticus
0.687 0.313 0.000
M07.38 Other psoriatic arthropathies (Other)
0.685 0.315 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.685 0.315 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.685 0.315 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.685 0.315 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.685 0.315 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.685 0.315 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.685 0.315 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.685 0.315 0.000
D82 Immunodeficiency associated with other major defects
0.684 0.316 0.000
D81 Combined immunodeficiencies
0.684 0.316 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.684 0.316 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.684 0.316 0.000
I36 Nonrheumatic tricuspid valve disorders
0.683 0.317 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.682 0.317 0.000
H34.2 Other retinal artery occlusions
0.682 0.318 0.000
I05-I09 Chronic rheumatic heart diseases
0.682 0.318 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.682 0.318 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.681 0.319 0.000
M06.38 Rheumatoid nodule (Other)
0.681 0.319 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.681 0.319 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.681 0.319 0.000
M06.33 Rheumatoid nodule (Forearm)
0.681 0.319 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.681 0.319 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.681 0.319 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.680 0.320 0.000
H55-H59 Other disorders of eye and adnexa
0.680 0.320 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.679 0.321 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.677 0.323 0.000
J95-J99 Other diseases of the respiratory system
0.677 0.323 0.000
J43.2 Centrilobular emphysema
0.677 0.323 0.000
E28 Ovarian dysfunction
0.677 0.323 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
D52.9 Folate deficiency anaemia, unspecified
0.676 0.324 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.676 0.324 0.000
J15.8 Other bacterial pneumonia
0.675 0.325 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.675 0.325 0.000
J15.5 Pneumonia due to Escherichia coli
0.675 0.325 0.000
J15.3 Pneumonia due to streptococcus, group B
0.675 0.325 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.675 0.325 0.000
E24 Cushing's syndrome
0.674 0.326 0.000
M14 Arthropathies in other diseases classified elsewhere
0.674 0.326 0.000
M89 Other disorders of bone
0.674 0.326 0.000
I74.5 Embolism and thrombosis of iliac artery
0.674 0.326 0.000
A65-A69 Other spirochaetal diseases
0.673 0.326 0.000
W75-W84 Other accidental threats to breathing
0.673 0.327 0.000
D61 Other aplastic anaemias
0.673 0.327 0.000
M75.8 Other shoulder lesions
0.672 0.328 0.000
D86.8 Sarcoidosis of other and combined sites
0.672 0.328 0.000
E78.4 Other hyperlipidaemia
0.671 0.329 0.000
I35.0 Aortic (valve) stenosis
0.671 0.329 0.000
J20 Acute bronchitis
0.670 0.330 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.669 0.331 0.000
D86.9 Sarcoidosis, unspecified
0.669 0.331 0.000
J90-J94 Other diseases of pleura
0.668 0.332 0.000
Y57.9 Drug or medicament, unspecified
0.668 0.332 0.000
B35.1 Tinea unguium
0.668 0.332 0.000
M11 Other crystal arthropathies
0.667 0.333 0.000
W50-W64 Exposure to animate mechanical forces
0.667 0.333 0.000
M13 Other arthritis
0.666 0.334 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.665 0.335 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.665 0.335 0.000
A75-A79 Rickettsioses
0.665 0.335 0.000
A70-A74 Other diseases caused by chlamydiae
0.665 0.335 0.000
A20-A28 Certain zoonotic bacterial diseases
0.665 0.335 0.000
M40-M43 Deforming dorsopathies
0.665 0.335 0.000
V90-V94 Water transport accidents
0.665 0.335 0.000
D58 Other hereditary haemolytic anaemias
0.665 0.335 0.000
E11.4 With neurological complications
0.664 0.336 0.000
W25 Contact with sharp glass
0.664 0.336 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.664 0.336 0.000
I46.0 Cardiac arrest with successful resuscitation
0.664 0.336 0.000
J32.3 Chronic sphenoidal sinusitis
0.664 0.336 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.664 0.336 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.663 0.337 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.663 0.337 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.663 0.337 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.663 0.337 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.663 0.337 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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