TreeWAS – Variant ID: rs66867947

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.001	0.999
I20-I25 Ischaemic heart diseases	0.000	0.028	0.972
I21 Acute myocardial infarction	0.000	0.061	0.939
I21.9 Acute myocardial infarction, unspecified	0.000	0.065	0.935
I22 Subsequent myocardial infarction	0.000	0.074	0.926
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.180	0.820
I25.4 Coronary artery aneurysm	0.000	0.195	0.805
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.234	0.766
I24 Other acute ischaemic heart diseases	0.000	0.242	0.758
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.243	0.757
I22.8 Subsequent myocardial infarction of other sites	0.000	0.247	0.753
I23 Certain current complications following acute myocardial infarction	0.000	0.261	0.739
I25.3 Aneurysm of heart	0.000	0.263	0.737
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.270	0.730
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I24.8 Other forms of acute ischaemic heart disease	0.000	0.291	0.709
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.298	0.702
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.300	0.700
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.319	0.681
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.327	0.673
I23.8 Other current complications following acute myocardial infarction	0.000	0.428	0.572
I20 Angina pectoris	0.000	0.449	0.551
I25.5 Ischaemic cardiomyopathy	0.000	0.461	0.538
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.470	0.530
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.470	0.530
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.470	0.530
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.470	0.530
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.470	0.530
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.470	0.530
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.470	0.530
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.483	0.517
I24.1 Dressler's syndrome	0.000	0.508	0.492
I20.0 Unstable angina	0.000	0.539	0.461
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.553	0.446
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.567	0.433
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.600	0.400
I20.8 Other forms of angina pectoris	0.000	0.611	0.389
I20.1 Angina pectoris with documented spasm	0.000	0.704	0.296
I20.9 Angina pectoris, unspecified	0.000	0.754	0.246
J84.1 Other interstitial pulmonary diseases with fibrosis	0.219	0.781	0.000
J84 Other interstitial pulmonary diseases	0.213	0.787	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.210	0.790	0.000
J84.8 Other specified interstitial pulmonary diseases	0.189	0.810	0.000
J84.0 Alveolar and parietoalveolar conditions	0.153	0.847	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.862	0.138
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.890	0.110
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.894	0.106
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.895	0.105
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.897	0.103
K91.4 Colostomy and enterostomy malfunction	0.000	0.899	0.101
K91.3 Postoperative intestinal obstruction	0.000	0.906	0.094
K91.1 Postgastric surgery syndromes	0.000	0.916	0.084
K91.5 Postcholecystectomy syndrome	0.000	0.923	0.077
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.933	0.067
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.936	0.064
J80-J84 Other respiratory diseases principally affecting the interstitium	0.030	0.970	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.023	0.977	0.000
H60.9 Otitis externa, unspecified	0.014	0.986	0.000
J81 Pulmonary oedema	0.014	0.986	0.000
H61.0 Perichondritis of external ear	0.013	0.987	0.000
H60 Otitis externa	0.012	0.988	0.000
H61.8 Other specified disorders of external ear	0.012	0.988	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.988	0.012
H61 Other disorders of external ear	0.012	0.988	0.000
H60-H62 Diseases of external ear	0.011	0.989	0.000
H60.8 Other otitis externa	0.010	0.990	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.990	0.010
H60.4 Cholesteatoma of external ear	0.010	0.990	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.009	0.990	0.000
H60.3 Other infective otitis externa	0.009	0.991	0.000
H60.0 Abscess of external ear	0.009	0.991	0.000
H60.2 Malignant otitis externa	0.009	0.991	0.000
N70.1 Chronic salpingitis and oophoritis	0.009	0.991	0.000
H49 Paralytic strabismus	0.000	0.991	0.009
M35.0 Sicca syndrome [Sjogren]	0.009	0.991	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.991	0.009
J80 Adult respiratory distress syndrome	0.008	0.991	0.001
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.992	0.008
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.008	0.992	0.000
K90-K93 Other diseases of the digestive system	0.000	0.992	0.008
H60.5 Acute otitis externa, non-infective	0.008	0.992	0.000
H60.1 Cellulitis of external ear	0.008	0.992	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.992	0.008
H49.9 Paralytic strabismus, unspecified	0.000	0.992	0.008
H61.3 Acquired stenosis of external ear canal	0.008	0.992	0.000
M81.9 Osteoporosis, unspecified	0.000	0.992	0.008
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.993	0.007
H61.9 Disorder of external ear, unspecified	0.007	0.993	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.993	0.007
H62.8 Other disorders of external ear in diseases classified elsewhere	0.007	0.993	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.007	0.993	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
H62.2 Otitis externa in mycoses	0.007	0.993	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.007	0.993	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
L60.8 Other nail disorders	0.007	0.993	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.000	0.993	0.007
H49.4 Progressive external ophthalmoplegia	0.000	0.993	0.007
H49.3 Total (external) ophthalmoplegia	0.000	0.993	0.007
H49.1 Fourth [trochlear] nerve palsy	0.000	0.994	0.006
H49.8 Other paralytic strabismus	0.000	0.994	0.006
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.994	0.006
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.994	0.006
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
N70 Salpingitis and oophoritis	0.006	0.994	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.994	0.006
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.994	0.006
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.994	0.006
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.994	0.006
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.006	0.994	0.000
N76.8 Other specified inflammation of vagina and vulva	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.994	0.006
Z93.2 Ileostomy status	0.000	0.994	0.006
Q89 Other congenital malformations, not elsewhere classified	0.006	0.994	0.000
M84.0 Malunion of fracture	0.000	0.994	0.006
N76 Other inflammation of vagina and vulva	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.995	0.005
M81 Osteoporosis without pathological fracture	0.000	0.995	0.005
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
Q89.2 Congenital malformations of other endocrine glands	0.005	0.995	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.995	0.005
Q83 Congenital malformations of breast	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.005	0.995	0.000
N72 Inflammatory disease of cervix uteri	0.005	0.995	0.000
M84.04 Malunion of fracture (Hand)	0.000	0.995	0.005
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.995	0.005
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.995	0.005
N76.3 Subacute and chronic vulvitis	0.005	0.995	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.995	0.005
N70-N77 Inflammatory diseases of female pelvic organs	0.005	0.995	0.000
N76.0 Acute vaginitis	0.005	0.995	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.995	0.005
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.995	0.005
K93.1 Megacolon in Chagas' disease	0.000	0.995	0.005
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.995	0.005
M84.03 Malunion of fracture (Forearm)	0.000	0.995	0.005
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
Q39.6 Diverticulum of oesophagus	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.005	0.995	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.005	0.995	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.995	0.005
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
Y85 Sequelae of transport accidents	0.000	0.995	0.005
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.995	0.000
Q84 Other congenital malformations of integument	0.004	0.995	0.000
Q81 Epidermolysis bullosa	0.004	0.995	0.000
Q80 Congenital ichthyosis	0.004	0.995	0.000
H61.1 Non-infective disorders of pinna	0.004	0.995	0.001
Q83.3 Accessory nipple	0.004	0.995	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
Q82.2 Mastocytosis	0.004	0.995	0.000
Q82.5 Congenital nonneoplastic naevus	0.004	0.995	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.005	0.995	0.000
Q39 Congenital malformations of oesophagus	0.004	0.995	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.995	0.005
Q83.1 Accessory breast	0.004	0.995	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.995	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.996	0.004
M85.8 Other specified disorders of bone density and structure	0.000	0.996	0.004
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.000	0.996	0.004
M84.09 Malunion of fracture (Site unspecified)	0.000	0.996	0.004
M84.08 Malunion of fracture (Other)	0.000	0.996	0.004
M84.00 Malunion of fracture (Multiple sites)	0.000	0.996	0.004
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
Z12 Special screening examination for neoplasms	0.000	0.996	0.004
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.004	0.996	0.000
H50.9 Strabismus, unspecified	0.000	0.996	0.004
Q40 Other congenital malformations of upper alimentary tract	0.004	0.996	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.996	0.004
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.004	0.996	0.000
M81.8 Other osteoporosis	0.000	0.996	0.004
M81.6 Localised osteoporosis [Lequesne]	0.000	0.996	0.004
M81.5 Idiopathic osteoporosis	0.000	0.996	0.004
M81.1 Postoophorectomy osteoporosis	0.000	0.996	0.004
M84 Disorders of continuity of bone	0.000	0.996	0.004
M85 Other disorders of bone density and structure	0.000	0.996	0.004
M84.01 Malunion of fracture (Shoulder region)	0.000	0.996	0.004
A04.7 Enterocolitis due to Clostridium difficile	0.004	0.996	0.000
Q85.1 Tuberous sclerosis	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.996	0.004
Q82.9 Congenital malformation of skin, unspecified	0.004	0.996	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.004	0.996	0.000
Q82.3 Incontinentia pigmenti	0.004	0.996	0.000
Q82.1 Xeroderma pigmentosum	0.004	0.996	0.000
Q83.9 Congenital malformation of breast, unspecified	0.004	0.996	0.000
Q83.2 Absent nipple	0.004	0.996	0.000
Q83.0 Congenital absence of breast with absent nipple	0.004	0.996	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.004	0.996	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.996	0.004
K22.4 Dyskinesia of oesophagus	0.004	0.996	0.000
Q82.0 Hereditary lymphoedema	0.004	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
N76.1 Subacute and chronic vaginitis	0.004	0.996	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.996	0.000
N70.0 Acute salpingitis and oophoritis	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.004	0.996	0.000
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
N76.5 Ulceration of vagina	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
Q83.8 Other congenital malformations of breast	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.000	0.996	0.004
N70.9 Salpingitis and oophoritis, unspecified	0.004	0.996	0.000
N76.6 Ulceration of vulva	0.004	0.996	0.000
N71 Inflammatory disease of uterus, except cervix	0.004	0.996	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.996	0.004
N76.2 Acute vulvitis	0.004	0.996	0.000
Q82.8 Other specified congenital malformations of skin	0.004	0.996	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
H61.2 Impacted cerumen	0.004	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.000	0.996	0.004
L60 Nail disorders	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.996	0.004
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.000	0.996	0.004
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
N73 Other female pelvic inflammatory diseases	0.004	0.996	0.000
M81.4 Drug-induced osteoporosis	0.000	0.996	0.004
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.996	0.000
Q80.8 Other congenital ichthyosis	0.003	0.996	0.000
Q80.4 Harlequin foetus	0.003	0.996	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.996	0.000
Q80.2 Lamellar ichthyosis	0.003	0.996	0.000
Q80.1 X-linked ichthyosis	0.003	0.996	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.996	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.996	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.996	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.996	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.996	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.996	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.996	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.996	0.000
Q84.6 Other congenital malformations of nails	0.003	0.996	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.996	0.000
Q84.4 Congenital leukonychia	0.003	0.996	0.000
Q84.3 Anonychia	0.003	0.996	0.000
Q84.2 Other congenital malformations of hair	0.003	0.996	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.996	0.000
Q84.0 Congenital alopecia	0.003	0.996	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.996	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.996	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.996	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.996	0.000
M80 Osteoporosis with pathological fracture	0.001	0.996	0.003
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.996	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.003	0.996	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.003	0.996	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.003	0.996	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.996	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.996	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.996	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.996	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.996	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.996	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.996	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.996	0.003
Q62.5 Duplication of ureter	0.003	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.996	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.997	0.003
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.997	0.003
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.997	0.003
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.997	0.003
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.997	0.003
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.997	0.003
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.997	0.003
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.997	0.003
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.997	0.003
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.000	0.997	0.003
Q63.0 Accessory kidney	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.997	0.003
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
M83 Adult osteomalacia	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.997	0.003
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
H50 Other strabismus	0.000	0.997	0.003
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.997	0.003
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.997	0.003
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.997	0.003
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.997	0.003
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.997	0.003
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.58 Idiopathic osteoporosis (Other)	0.000	0.997	0.003
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.997	0.003
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.997	0.003
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.997	0.003
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.997	0.003
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.997	0.003
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.997	0.003
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.997	0.003
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.997	0.003
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.997	0.003
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.997	0.003
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.997	0.003
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.997	0.003
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.997	0.003
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.997	0.003
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.997	0.003
M81.89 Other osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.88 Other osteoporosis (Other)	0.000	0.997	0.003
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.86 Other osteoporosis (Lower leg)	0.000	0.997	0.003
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.84 Other osteoporosis (Hand)	0.000	0.997	0.003
M81.83 Other osteoporosis (Forearm)	0.000	0.997	0.003
M81.82 Other osteoporosis (Upper arm)	0.000	0.997	0.003
M81.81 Other osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.80 Other osteoporosis (Multiple sites)	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
M35.2 Behcet's disease	0.003	0.997	0.000
N76.4 Abscess of vulva	0.003	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.003
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.003
M85.9 Disorder of bone density and structure, unspecified	0.000	0.997	0.003
M85.6 Other cyst of bone	0.000	0.997	0.003
M85.5 Aneurysmal bone cyst	0.000	0.997	0.003
M85.4 Solitary bone cyst	0.000	0.997	0.003
M85.3 Osteitis condensans	0.000	0.997	0.003
M85.2 Hyperostosis of skull	0.000	0.997	0.003
M85.1 Skeletal fluorosis	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.003	0.997	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.997	0.003
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.997	0.003
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.997	0.003
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.997	0.003
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.997	0.003
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.997	0.003
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.997	0.003
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.003	0.997	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
Z99.8 Dependence on other enabling machines and devices	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.997	0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.003	0.997	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.003	0.997	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.003	0.997	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.003	0.997	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.003	0.997	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.003	0.997	0.000
N74.0 Tuberculous infection of cervix uteri	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.997	0.003
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.997	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.997	0.003
M81.28 Osteoporosis of disuse (Other)	0.000	0.997	0.003
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.997	0.003
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.997	0.003
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.997	0.003
M81.24 Osteoporosis of disuse (Hand)	0.000	0.997	0.003
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.997	0.003
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.997	0.003
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.997	0.003
N71.0 Acute inflammatory disease of uterus	0.003	0.997	0.000
Z12.3 Special screening examination for neoplasm of breast	0.000	0.997	0.003
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
Q39.4 Oesophageal web	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.997	0.003
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.997	0.002
D81 Combined immunodeficiencies	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.003	0.997	0.000
L60.4 Beau's lines	0.003	0.997	0.000
L60.1 Onycholysis	0.003	0.997	0.000
L60.0 Ingrowing nail	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.997	0.003
M84.2 Delayed union of fracture	0.000	0.997	0.003
N73.5 Female pelvic peritonitis, unspecified	0.003	0.997	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
L60.2 Onychogryphosis	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations