TreeWAS – Variant ID: rs6690583

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.2 Mechanical complication of internal fixation device of other bones	0.127	0.873	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.125	0.875	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.119	0.881	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.117	0.883	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.106	0.894	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.105	0.895	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.102	0.898	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.098	0.902	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.085	0.915	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.077	0.923	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.071	0.928	0.000
L03.1 Cellulitis of other parts of limb	0.033	0.967	0.000
N85.2 Hypertrophy of uterus	0.000	0.984	0.016
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.014	0.986	0.000
M79.8 Other specified soft tissue disorders	0.014	0.986	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.012	0.988	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.012	0.988	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.011	0.989	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.011	0.989	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.011	0.989	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.011	0.989	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.010	0.990	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.010	0.990	0.000
M79.88 Other specified soft tissue disorders (Other)	0.010	0.990	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.010	0.990	0.000
D03 Melanoma in situ	0.009	0.991	0.000
D09.0 Bladder	0.008	0.992	0.000
D09 Carcinoma in situ of other and unspecified sites	0.008	0.992	0.000
D00-D09 In situ neoplasms	0.007	0.993	0.000
R52.1 Chronic intractable pain	0.007	0.993	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.007	0.993	0.000
D03.8 Melanoma in situ of other sites	0.007	0.993	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.007	0.993	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.007	0.993	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.007	0.993	0.000
R52.2 Other chronic pain	0.007	0.993	0.000
D03.0 Melanoma in situ of lip	0.006	0.993	0.000
D03.9 Melanoma in situ, unspecified	0.006	0.994	0.000
D09.9 Carcinoma in situ, unspecified	0.006	0.994	0.000
D07.1 Vulva	0.006	0.994	0.000
D03.4 Melanoma in situ of scalp and neck	0.006	0.994	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.006	0.994	0.000
R52 Pain, not elsewhere classified	0.006	0.994	0.000
S72.10 Pertrochanteric fracture (closed)	0.006	0.994	0.000
D09.7 Carcinoma in situ of other specified sites	0.006	0.994	0.000
D09.3 Thyroid and other endocrine glands	0.006	0.994	0.000
D09.2 Eye	0.006	0.994	0.000
D07.2 Vagina	0.006	0.994	0.000
D04 Carcinoma in situ of skin	0.006	0.994	0.000
C43.5 Malignant melanoma of trunk	0.000	0.994	0.006
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.005	0.994	0.000
D06 Carcinoma in situ of cervix uteri	0.005	0.995	0.000
D07.0 Endometrium	0.005	0.995	0.000
D09.1 Other and unspecified urinary organs	0.005	0.995	0.000
M35.3 Polymyalgia rheumatica	0.005	0.995	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.005	0.995	0.000
D07.6 Other and unspecified male genital organs	0.005	0.995	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.005	0.995	0.000
D04.2 Skin of ear and external auricular canal	0.005	0.995	0.000
R52.0 Acute pain	0.005	0.995	0.000
D07.3 Other and unspecified female genital organs	0.005	0.995	0.000
M25.56 Pain in joint (Lower leg)	0.005	0.995	0.000
D04.1 Skin of eyelid, including canthus	0.005	0.995	0.000
L03 Cellulitis	0.005	0.995	0.000
D07.5 Prostate	0.005	0.995	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.005	0.995	0.000
D07.4 Penis	0.005	0.995	0.000
D05 Carcinoma in situ of breast	0.005	0.995	0.000
C18.3 Hepatic flexure	0.005	0.995	0.000
D04.5 Skin of trunk	0.005	0.995	0.000
D05.7 Other carcinoma in situ of breast	0.004	0.996	0.000
D06.9 Cervix, unspecified	0.004	0.996	0.000
L03.3 Cellulitis of trunk	0.004	0.996	0.000
D00.1 Oesophagus	0.004	0.996	0.000
D00.0 Lip, oral cavity and pharynx	0.004	0.996	0.000
D04.8 Skin of other sites	0.004	0.996	0.000
D00.2 Stomach	0.004	0.996	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.996	0.004
D06.7 Other parts of cervix	0.004	0.996	0.000
D04.0 Skin of lip	0.004	0.996	0.000
D01.5 Liver, gallbladder and bile ducts	0.004	0.996	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.004	0.996	0.000
D04.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
G81.9 Hemiplegia, unspecified	0.000	0.996	0.004
D06.1 Exocervix	0.004	0.996	0.000
D04.9 Skin, unspecified	0.004	0.996	0.000
D06.0 Endocervix	0.004	0.996	0.000
D03.5 Melanoma in situ of trunk	0.004	0.996	0.000
H53.9 Visual disturbance, unspecified	0.000	0.996	0.004
D05.0 Lobular carcinoma in situ	0.004	0.996	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.996	0.004
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
D02.4 Respiratory system, unspecified	0.004	0.996	0.000
D02.3 Other parts of respiratory system	0.004	0.996	0.000
D02.1 Trachea	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
R52.9 Pain, unspecified	0.004	0.996	0.000
D01.9 Digestive organ, unspecified	0.004	0.996	0.000
D01.7 Other specified digestive organs	0.004	0.996	0.000
D01.4 Other and unspecified parts of intestine	0.004	0.996	0.000
D01.1 Rectosigmoid junction	0.004	0.996	0.000
D04.4 Skin of scalp and neck	0.004	0.996	0.000
D02.2 Bronchus and lung	0.004	0.996	0.000
C18.9 Colon, unspecified	0.004	0.996	0.000
D01.0 Colon	0.004	0.996	0.000
D01.2 Rectum	0.003	0.996	0.000
D02.0 Larynx	0.004	0.996	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.996	0.004
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
C18.4 Transverse colon	0.004	0.996	0.000
S72.1 Pertrochanteric fracture	0.003	0.996	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.997	0.003
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
K62.1 Rectal polyp	0.000	0.997	0.003
D01.3 Anus and anal canal	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.003	0.997	0.000
L03.0 Cellulitis of finger and toe	0.003	0.997	0.000
G62 Other polyneuropathies	0.003	0.997	0.000
D04.7 Skin of lower limb, including hip	0.003	0.997	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.997	0.003
G62.8 Other specified polyneuropathies	0.003	0.997	0.000
C18.5 Splenic flexure	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
I46.0 Cardiac arrest with successful resuscitation	0.003	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.000	0.997	0.003
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
S20.2 Contusion of thorax	0.003	0.997	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
C18.8 Overlapping lesion of colon	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
S72.11 Pertrochanteric fracture (open)	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
C02.1 Border of tongue	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.997	0.003
Z75 Problems related to medical facilities and other health care	0.003	0.997	0.000
L03.2 Cellulitis of face	0.003	0.997	0.000
M79.19 Myalgia (Site unspecified)	0.003	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
Z98.1 Arthrodesis status	0.000	0.997	0.003
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.997	0.003
N83.0 Follicular cyst of ovary	0.003	0.997	0.000
R68.8 Other specified general symptoms and signs	0.003	0.997	0.000
Z75.8 Other problems related to medical facilities and other health care	0.003	0.997	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.002
E27.0 Other adrenocortical overactivity	0.000	0.997	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.002
M79.1 Myalgia	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
M79.16 Myalgia (Lower leg)	0.002	0.998	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.000	0.998	0.002
L03.8 Cellulitis of other sites	0.002	0.998	0.000
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
M79.18 Myalgia (Other)	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
Z75.4 Unavailability and inaccessibility of other helping agencies	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.998	0.002
Z75.9 Unspecified problem related to medical facilities and other health care	0.002	0.998	0.000
Z75.5 Holiday relief care	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
K62.3 Rectal prolapse	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
C18.6 Descending colon	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
Z75.0 Medical services not available in home	0.002	0.998	0.000
M79.17 Myalgia (Ankle and foot)	0.002	0.998	0.000
M79.14 Myalgia (Hand)	0.002	0.998	0.000
M79.13 Myalgia (Forearm)	0.002	0.998	0.000
M79.12 Myalgia (Upper arm)	0.002	0.998	0.000
G81 Hemiplegia	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
D26.1 Corpus uteri	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
Z75.2 Other waiting period for investigation and treatment	0.002	0.998	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.002	0.998	0.000
C02.4 Lingual tonsil	0.000	0.998	0.002
D48.6 Breast	0.002	0.998	0.000
E24 Cushing's syndrome	0.000	0.998	0.002
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
M35 Other systemic involvement of connective tissue	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
M35.2 Behcet's disease	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.998	0.002
R16.1 Splenomegaly, not elsewhere classified	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.001	0.998	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
C02.0 Dorsal surface of tongue	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
G81.1 Spastic hemiplegia	0.000	0.998	0.002
M35.8 Other specified systemic involvement of connective tissue	0.002	0.998	0.000
N80.8 Other endometriosis	0.002	0.998	0.000
E32 Diseases of thymus	0.000	0.998	0.002
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.001	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.000	0.998	0.002
S72 Fracture of femur	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
O02.1 Missed abortion	0.002	0.998	0.000
E29 Testicular dysfunction	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
E25 Adrenogenital disorders	0.000	0.998	0.002
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.998	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.998	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.998	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
M79.11 Myalgia (Shoulder region)	0.001	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
C02.2 Ventral surface of tongue	0.000	0.998	0.001
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.001
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
J12.9 Viral pneumonia, unspecified	0.002	0.998	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.001
R09.0 Asphyxia	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.998	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.998	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.998	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.998	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.998	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.998	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.998	0.001
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.001
E30.8 Other disorders of puberty	0.000	0.998	0.001
E30.1 Precocious puberty	0.000	0.998	0.001
E30.0 Delayed puberty	0.000	0.998	0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.001
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.002	0.998	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.001
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.001	0.998	0.000
M79.9 Soft tissue disorder, unspecified	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
G64 Other disorders of peripheral nervous system	0.001	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.001
E32.8 Other diseases of thymus	0.000	0.998	0.001
E32.1 Abscess of thymus	0.000	0.998	0.001
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.001
M35.7 Hypermobility syndrome	0.001	0.998	0.000
M79.3 Panniculitis, unspecified	0.001	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.001
D69.0 Allergic purpura	0.000	0.998	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.001
E31.8 Other polyglandular dysfunction	0.000	0.998	0.001
E31.1 Polyglandular hyperfunction	0.000	0.998	0.001
E32.9 Disease of thymus, unspecified	0.000	0.998	0.001
S72.7 Multiple fractures of femur	0.001	0.998	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.002	0.998	0.000
R68 Other general symptoms and signs	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.000	0.998	0.001
E29.0 Testicular hyperfunction	0.000	0.998	0.001
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
D48.5 Skin	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.001
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.001
E25.8 Other adrenogenital disorders	0.000	0.998	0.001
G61.1 Serum neuropathy	0.001	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.001
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
E26 Hyperaldosteronism	0.000	0.998	0.001
M79.93 Soft tissue disorder, unspecified (Forearm)	0.001	0.998	0.000
I47.2 Ventricular tachycardia	0.002	0.998	0.000
N76.4 Abscess of vulva	0.000	0.998	0.001
R68.3 Clubbing of fingers	0.001	0.998	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.001	0.999	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.001	0.999	0.000
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
D10.5 Other parts of oropharynx	0.001	0.999	0.000
D69.1 Qualitative platelet defects	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.999	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.999	0.001
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.001	0.999	0.000
J84 Other interstitial pulmonary diseases	0.001	0.999	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.999	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
D48.4 Peritoneum	0.001	0.999	0.000
E20.1 Pseudohypoparathyroidism	0.000	0.999	0.001
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.001	0.999	0.000
C21.1 Anal canal	0.000	0.999	0.001
E20.0 Idiopathic hypoparathyroidism	0.000	0.999	0.001
M89.8 Other specified disorders of bone	0.001	0.999	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.999	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.999	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.999	0.001
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.001	0.999	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
D48.1 Connective and other soft tissue	0.001	0.999	0.000
E20.8 Other hypoparathyroidism	0.000	0.999	0.001
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
K22.2 Oesophageal obstruction	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
D48.2 Peripheral nerves and autonomic nervous system	0.001	0.999	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.999	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.001	0.999	0.000
J17.2 Pneumonia in mycoses	0.001	0.999	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.001	0.999	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.001	0.999	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.001	0.999	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.001	0.999	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.001	0.999	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.001	0.999	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.001	0.999	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.999	0.001
Q25.4 Other congenital malformations of aorta	0.000	0.999	0.001
D69 Purpura and other haemorrhagic conditions	0.000	0.999	0.001
J14 Pneumonia due to Haemophilus influenzae	0.001	0.999	0.000
J81 Pulmonary oedema	0.001	0.999	0.000
M79.39 Panniculitis, unspecified (Site unspecified)	0.001	0.999	0.000
M79.38 Panniculitis, unspecified (Other)	0.001	0.999	0.000
M79.37 Panniculitis, unspecified (Ankle and foot)	0.001	0.999	0.000
M79.36 Panniculitis, unspecified (Lower leg)	0.001	0.999	0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M79.34 Panniculitis, unspecified (Hand)	0.001	0.999	0.000
M79.33 Panniculitis, unspecified (Forearm)	0.001	0.999	0.000
M79.32 Panniculitis, unspecified (Upper arm)	0.001	0.999	0.000
M79.31 Panniculitis, unspecified (Shoulder region)	0.001	0.999	0.000
M79.30 Panniculitis, unspecified (Multiple sites)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
D48.3 Retroperitoneum	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.999	0.001
G54.9 Nerve root and plexus disorder, unspecified	0.001	0.999	0.000
J17.3 Pneumonia in parasitic diseases	0.001	0.999	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.001	0.999	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.000	0.999	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.999	0.001
R68.1 Nonspecific symptoms peculiar to infancy	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.001	0.999	0.000
G60 Hereditary and idiopathic neuropathy	0.001	0.999	0.000
J17 Pneumonia in diseases classified elsewhere	0.001	0.999	0.000
Q25 Congenital malformations of great arteries	0.000	0.999	0.001
M79.98 Soft tissue disorder, unspecified (Other)	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.999	0.001
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.999	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.999	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.999	0.001
E29.1 Testicular hypofunction	0.000	0.999	0.001
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.999	0.000
L03.9 Cellulitis, unspecified	0.001	0.999	0.000
M79.2 Neuralgia and neuritis, unspecified	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.999	0.001
D10 Benign neoplasm of mouth and pharynx	0.001	0.999	0.000
E34 Other endocrine disorders	0.000	0.999	0.001
J12 Viral pneumonia, not elsewhere classified	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
C05.0 Hard palate	0.000	0.999	0.001
C13.0 Postcricoid region	0.000	0.999	0.001
E26.8 Other hyperaldosteronism	0.000	0.999	0.001
E26.1 Secondary hyperaldosteronism	0.000	0.999	0.001
M90.6 Osteitis deformans in neoplastic disease	0.001	0.999	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T79.5 Traumatic anuria	0.001	0.999	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.999	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.001	0.999	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.999	0.000
J15.1 Pneumonia due to Pseudomonas	0.001	0.999	0.000
J84.8 Other specified interstitial pulmonary diseases	0.001	0.999	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.000	0.999	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.999	0.001
C13 Malignant neoplasm of hypopharynx	0.000	0.999	0.001
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.999	0.001
G31.2 Degeneration of nervous system due to alcohol	0.001	0.999	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.999	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T79.9 Unspecified early complication of trauma	0.001	0.999	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.001	0.999	0.000
T79.1 Fat embolism (traumatic)	0.001	0.999	0.000
T79.0 Air embolism (traumatic)	0.001	0.999	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.999	0.001
C05 Malignant neoplasm of palate	0.000	0.999	0.001
Q28 Other congenital malformations of circulatory system	0.000	0.999	0.001
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.999	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.999	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.001	0.999	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.999	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.999	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.999	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.999	0.000
M90.0 Tuberculosis of bone	0.001	0.999	0.000
Q25.1 Coarctation of aorta	0.000	0.999	0.001
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.999	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations