TreeWAS – Variant ID: rs6779678

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
K80 Cholelithiasis	1.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000
K82 Other diseases of gallbladder	1.000	0.000
K82.4 Cholesterolosis of gallbladder	1.000	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	1.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.999	0.001
K80.2 Calculus of gallbladder without cholecystitis	0.999	0.001
K81 Cholecystitis	0.997	0.003
K83 Other diseases of biliary tract	0.983	0.017
K81.1 Chronic cholecystitis	0.978	0.022
K83.8 Other specified diseases of biliary tract	0.966	0.034
K81.0 Acute cholecystitis	0.952	0.048
K86 Other diseases of pancreas	0.946	0.054
K86.8 Other specified diseases of pancreas	0.936	0.064
K80.8 Other cholelithiasis	0.907	0.093
K83.0 Cholangitis	0.893	0.107
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.863	0.137
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.857	0.143
M50-M54 Other dorsopathies	0.856	0.144
M45-M49 Spondylopathies	0.852	0.148
K82.2 Perforation of gallbladder	0.849	0.150
M47 Spondylosis	0.847	0.153
M54 Dorsalgia	0.843	0.157
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.840	0.160
M54.5 Low back pain	0.835	0.165
S90-S99 Injuries to the ankle and foot	0.830	0.170
S60-S69 Injuries to the wrist and hand	0.827	0.173
M47.8 Other spondylosis	0.824	0.176
M50 Cervical disk disorders	0.824	0.176
S66 Injury of muscle and tendon at wrist and hand level	0.821	0.179
S70-S79 Injuries to the hip and thigh	0.816	0.184
M20-M25 Other joint disorders	0.813	0.187
# Top node	0.811	0.189
M47.9 Spondylosis, unspecified	0.811	0.189
M54.56 Low back pain (Lumbar region)	0.811	0.189
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.809	0.191
K82.1 Hydrops of gallbladder	0.805	0.195
Chapter IV Endocrine, nutritional and metabolic diseases	0.805	0.195
K85 Acute pancreatitis	0.801	0.198
Chapter XI Diseases of the digestive system	0.796	0.204
M50.0 Cervical disk disorder with myelopathy	0.794	0.206
S40-S49 Injuries to the shoulder and upper arm	0.792	0.208
E10-E14 Diabetes mellitus	0.791	0.209
M47.82 Other spondylosis (Cervical region)	0.791	0.209
T93 Sequelae of injuries of lower limb	0.789	0.211
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.787	0.213
M24 Other specific joint derangements	0.787	0.213
E70-E90 Metabolic disorders	0.783	0.217
K81.9 Cholecystitis, unspecified	0.783	0.217
E78.0 Pure hypercholesterolaemia	0.781	0.219
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.781	0.219
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.774	0.226
E11 Non-insulin-dependent diabetes mellitus	0.772	0.228
T20-T25 Burns and corrosions of external body surface, specified by site	0.771	0.228
S00-S09 Injuries to the head	0.766	0.234
E11.9 Without complications	0.766	0.234
M47.86 Other spondylosis (Lumbar region)	0.765	0.235
S92 Fracture of foot, except ankle	0.763	0.237
M40-M43 Deforming dorsopathies	0.760	0.239
Chapter XXII Codes for special purposes	0.760	0.240
K83.9 Disease of biliary tract, unspecified	0.758	0.242
M53 Other dorsopathies, not elsewhere classified	0.758	0.242
M23 Internal derangement of knee	0.754	0.246
S40 Superficial injury of shoulder and upper arm	0.751	0.249
T93.2 Sequelae of other fractures of lower limb	0.750	0.250
E87 Other disorders of fluid, electrolyte and acid-base balance	0.747	0.253
S90 Superficial injury of ankle and foot	0.744	0.256
K82.3 Fistula of gallbladder	0.742	0.257
M47.96 Spondylosis, unspecified (Lumbar region)	0.739	0.261
K70-K77 Diseases of liver	0.739	0.261
M54.54 Low back pain-Thoracic	0.737	0.263
S02 Fracture of skull and facial bones	0.735	0.265
K82.9 Disease of gallbladder, unspecified	0.726	0.274
M43 Other deforming dorsopathies	0.723	0.277
M24.0 Loose body in joint	0.723	0.277
S30 Superficial injury of abdomen, lower back and pelvis	0.721	0.279
M23.8 Other internal derangements of knee	0.720	0.280
S70 Superficial injury of hip and thigh	0.719	0.281
M54.57 Low back pain (Lumbosacral region)	0.718	0.282
K80.3 Calculus of bile duct with cholangitis	0.717	0.283
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283
K82.0 Obstruction of gallbladder	0.717	0.283
S72 Fracture of femur	0.717	0.283
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.716	0.284
K81.8 Other cholecystitis	0.715	0.285
E87.1 Hypo-osmolality and hyponatraemia	0.711	0.289
K70 Alcoholic liver disease	0.709	0.291
M54.4 Lumbago with sciatica	0.709	0.291
Chapter XV Pregnancy, childbirth and the puerperium	0.708	0.292
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.708	0.292
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.708	0.292
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.706	0.294
K83.5 Biliary cyst	0.705	0.295
K83.4 Spasm of sphincter of Oddi	0.705	0.295
K83.3 Fistula of bile duct	0.705	0.295
K83.2 Perforation of bile duct	0.705	0.295
E10 Insulin-dependent diabetes mellitus	0.703	0.297
S31 Open wound of abdomen, lower back and pelvis	0.701	0.299
E87.5 Hyperkalaemia	0.700	0.300
S92.0 Fracture of calcaneus	0.699	0.301
M47.99 Spondylosis, unspecified (Site unspecified)	0.696	0.304
M91-M94 Chondropathies	0.696	0.304
T90 Sequelae of injuries of head	0.695	0.305
M43.1 Spondylolisthesis	0.695	0.305
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.690	0.310
K86.9 Disease of pancreas, unspecified	0.689	0.311
K86.1 Other chronic pancreatitis	0.688	0.312
E78.9 Disorder of lipoprotein metabolism, unspecified	0.688	0.312
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.688	0.312
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.687	0.313
M49 Spondylopathies in diseases classified elsewhere	0.686	0.314
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.686	0.314
M48 Other spondylopathies	0.684	0.316
K80.4 Calculus of bile duct with cholecystitis	0.682	0.318
T91 Sequelae of injuries of neck and trunk	0.673	0.326
M50.2 Other cervical disk displacement	0.673	0.327
T00-T07 Injuries involving multiple body regions	0.672	0.328
E11.4 With neurological complications	0.671	0.329
K70.9 Alcoholic liver disease, unspecified	0.670	0.330
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.670	0.330
M54.6 Pain in thoracic spine	0.669	0.331
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.668	0.332
O85-O92 Complications predominantly related to the puerperium	0.667	0.333
S60 Superficial injury of wrist and hand	0.667	0.333
S79 Other and unspecified injuries of hip and thigh	0.666	0.334
S96 Injury of muscle and tendon at ankle and foot level	0.666	0.334
M21 Other acquired deformities of limbs	0.664	0.336
S02.4 Fracture of malar and maxillary bones	0.662	0.338
M24.1 Other articular cartilage disorders	0.661	0.338
K82.8 Other specified diseases of gallbladder	0.658	0.342
M00-M03 Infectious arthropathies	0.656	0.344
S90.8 Other superficial injuries of ankle and foot	0.656	0.344
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.655	0.345
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.655	0.345
T15-T19 Effects of foreign body entering through natural orifice	0.655	0.345
S92.00 Fracture of calcaneus (closed)	0.653	0.347
E10.2 With renal complications	0.653	0.347
K72 Hepatic failure, not elsewhere classified	0.652	0.348
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.649	0.351
S06 Intracranial injury	0.648	0.352
E11.8 With unspecified complications	0.647	0.353
U80 Agent resistant to penicillin and related antibiotics	0.647	0.353
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.647	0.353
T94 Sequelae of injuries involving multiple and unspecified body regions	0.644	0.356
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.644	0.356
E20-E35 Disorders of other endocrine glands	0.642	0.358
M43.17 Spondylolisthesis (Lumbosacral region)	0.642	0.358
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.640	0.360
K85.9 Acute pancreatitis, unspecified	0.639	0.361
E78.6 Lipoprotein deficiency	0.638	0.362
M54.9 Dorsalgia, unspecified	0.638	0.362
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.637	0.363
M23.4 Loose body in knee	0.637	0.363
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.637	0.363
S66.8 Injury of other muscles and tendons at wrist and hand level	0.636	0.364
T98 Sequelae of other and unspecified effects of external causes	0.636	0.364
S67 Crushing injury of wrist and hand	0.635	0.365
M05-M14 Inflammatory polyarthropathies	0.633	0.367
S65 Injury of blood vessels at wrist and hand level	0.631	0.369
M34 Systemic sclerosis	0.630	0.370
S63.6 Sprain and strain of finger(s)	0.629	0.371
M24.02 Loose body in joint (Upper arm)	0.627	0.373
S20-S29 Injuries to the thorax	0.627	0.373
S30.0 Contusion of lower back and pelvis	0.627	0.373
K70.2 Alcoholic fibrosis and sclerosis of liver	0.626	0.374
E13 Other specified diabetes mellitus	0.625	0.374
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.625	0.375
M24.07 Loose body in joint (Ankle and foot)	0.625	0.375
S40.8 Other superficial injuries of shoulder and upper arm	0.623	0.377
M47.2 Other spondylosis with radiculopathy	0.623	0.377
M24.4 Recurrent dislocation and subluxation of joint	0.623	0.377
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.622	0.378
M47.84 Other spondylosis (Thoracic region)	0.620	0.380
T33-T35 Frostbite	0.619	0.381
T26-T28 Burns and corrosions confined to eye and internal organs	0.619	0.381
M24.16 Other articular cartilage disorders (Lower leg)	0.619	0.381
M43.16 Spondylolisthesis (Lumbar region)	0.619	0.381
S05 Injury of eye and orbit	0.618	0.382
S36 Injury of intra-abdominal organs	0.613	0.386
T21 Burn and corrosion of trunk	0.611	0.388
M92 Other juvenile osteochondrosis	0.611	0.389
S02.40 Fracture of malar and maxillary bones (closed)	0.609	0.391
S72.0 Fracture of neck of femur	0.608	0.392
T66-T78 Other and unspecified effects of external causes	0.608	0.392
M47.0 Anterior spinal and vertebral artery compression syndromes	0.608	0.392
K70.0 Alcoholic fatty liver	0.608	0.392
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.607	0.393
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.607	0.393
S42 Fracture of shoulder and upper arm	0.605	0.394
S02.2 Fracture of nasal bones	0.605	0.395
M54.8 Other dorsalgia	0.605	0.395
M54.0 Panniculitis affecting regions of neck and back	0.605	0.395
M24.6 Ankylosis of joint	0.604	0.396
K85.1 Biliary acute pancreatitis	0.603	0.397
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.603	0.397
T95 Sequelae of burns, corrosions and frostbite	0.602	0.397
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.602	0.397
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.602	0.397
M24.5 Contracture of joint	0.602	0.398
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.602	0.398
E78.8 Other disorders of lipoprotein metabolism	0.602	0.398
S31.1 Open wound of abdominal wall	0.602	0.398
M33 Dermatopolymyositis	0.602	0.398
S02.0 Fracture of vault of skull	0.601	0.399
M46 Other inflammatory spondylopathies	0.600	0.400
M54.53 Low back pain-Cervicothoracic	0.599	0.401
M54.52 Low back pain-Cervical	0.599	0.401
M54.51 Low back pain-Occipit-atl-axl	0.599	0.401
E78.2 Mixed hyperlipidaemia	0.598	0.402
S90.3 Contusion of other and unspecified parts of foot	0.598	0.402
T25 Burn and corrosion of ankle and foot	0.598	0.402
S70.1 Contusion of thigh	0.597	0.403
M54.2 Cervicalgia	0.596	0.404
M23.9 Internal derangement of knee, unspecified	0.596	0.404
S02.1 Fracture of base of skull	0.595	0.405
S98 Traumatic amputation of ankle and foot	0.595	0.405
S97 Crushing injury of ankle and foot	0.595	0.405
S95 Injury of blood vessels at ankle and foot level	0.595	0.405
S94 Injury of nerves at ankle and foot level	0.595	0.405
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.595	0.405
E10.1 With ketoacidosis	0.595	0.405
S71 Open wound of hip and thigh	0.594	0.406
U51 Admission status on psychiatric patients	0.593	0.407
K73 Chronic hepatitis, not elsewhere classified	0.593	0.407
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.591	0.409
M47.85 Other spondylosis (Thoracolumbar region)	0.591	0.409
M47.83 Other spondylosis (Cervicothoracic region)	0.591	0.409
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.591	0.409
M50.9 Cervical disk disorder, unspecified	0.590	0.409
M50.8 Other cervical disk disorders	0.590	0.409
M21.6 Other acquired deformities of ankle and foot	0.589	0.411
M25 Other joint disorders, not elsewhere classified	0.589	0.411
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.589	0.411
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.589	0.411
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.589	0.411
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.588	0.412
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.587	0.413
E80 Disorders of porphyrin and bilirubin metabolism	0.586	0.413
M54.46 Lumbago with sciatica (Lumbar region)	0.586	0.414
M47.89 Other spondylosis (Site unspecified)	0.586	0.414
S78 Traumatic amputation of hip and thigh	0.585	0.415
S77 Crushing injury of hip and thigh	0.585	0.415
S76 Injury of muscle and tendon at hip and thigh level	0.585	0.415
S75 Injury of blood vessels at hip and thigh level	0.585	0.415
S74 Injury of nerves at hip and thigh level	0.585	0.415
K72.0 Acute and subacute hepatic failure	0.584	0.415
T92 Sequelae of injuries of upper limb	0.583	0.417
M50.1 Cervical disk disorder with radiculopathy	0.583	0.417
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.583	0.417
M32 Systemic lupus erythematosus	0.583	0.417
Chapter XVI Certain conditions originating in the perinatal period	0.582	0.418
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.582	0.418
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.582	0.418
M47.94 Spondylosis, unspecified (Thoracic region)	0.582	0.418
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.582	0.418
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.582	0.418
S37 Injury of urinary and pelvic organs	0.581	0.419
S99 Other and unspecified injuries of ankle and foot	0.580	0.420
M86-M90 Other osteopathies	0.580	0.420
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.580	0.420
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.580	0.420
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.580	0.420
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.580	0.420
S92.5 Fracture of other toe	0.579	0.421
S72.4 Fracture of lower end of femur	0.578	0.421
S70.9 Superficial injury of hip and thigh, unspecified	0.578	0.422
T91.2 Sequelae of other fracture of thorax and pelvis	0.577	0.423
S40.0 Contusion of shoulder and upper arm	0.577	0.423
M06 Other rheumatoid arthritis	0.575	0.425
K85.8 Other acute pancreatitis	0.575	0.425
K85.3 Drug-induced acute pancreatitis	0.575	0.425
K85.2 Alcohol-induced acute pancreatitis	0.575	0.425
K85.0 Idiopathic acute pancreatitis	0.575	0.425
M25.7 Osteophyte	0.573	0.427
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.572	0.428
O86 Other puerperal infections	0.572	0.428
T93.9 Sequelae of unspecified injury of lower limb	0.572	0.428
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.572	0.428
S92.1 Fracture of talus	0.570	0.430
S48 Traumatic amputation of shoulder and upper arm	0.568	0.432
S45 Injury of blood vessels at shoulder and upper arm level	0.568	0.432
S44 Injury of nerves at shoulder and upper arm level	0.568	0.432
S47 Crushing injury of shoulder and upper arm	0.568	0.432
E12 Malnutrition-related diabetes mellitus	0.567	0.432
T79-T79 Certain early complications of trauma	0.567	0.432
M49.5 Collapsed vertebra in diseases classified elsewhere	0.567	0.433
S92.2 Fracture of other tarsal bone(s)	0.566	0.434
S41 Open wound of shoulder and upper arm	0.566	0.434
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.566	0.434
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.566	0.434
T93.4 Sequelae of injury of nerve of lower limb	0.566	0.434
T93.0 Sequelae of open wound of lower limb	0.566	0.434
E87.7 Fluid overload	0.565	0.434
M47.87 Other spondylosis (Lumbosacral region)	0.565	0.435
E24 Cushing's syndrome	0.565	0.435
M24.9 Joint derangement, unspecified	0.564	0.436
M24.7 Protrusio acetabuli	0.564	0.436
S60.0 Contusion of finger(s) without damage to nail	0.563	0.436
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.563	0.437
M23.5 Chronic instability of knee	0.563	0.437
S49 Other and unspecified injuries of shoulder and upper arm	0.563	0.437
E84 Cystic fibrosis	0.562	0.438
E79 Disorders of purine and pyrimidine metabolism	0.562	0.438
E77 Disorders of glycoprotein metabolism	0.562	0.438
E76 Disorders of glycosaminoglycan metabolism	0.562	0.438
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.562	0.438
E72 Other disorders of amino-acid metabolism	0.562	0.438
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.562	0.438
E70 Disorders of aromatic amino-acid metabolism	0.562	0.438
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.562	0.438
S30.2 Contusion of external genital organs	0.561	0.439
E78.3 Hyperchylomicronaemia	0.560	0.440
T90.5 Sequelae of intracranial injury	0.559	0.441
S79.9 Unspecified injury of hip and thigh	0.559	0.441
E73 Lactose intolerance	0.557	0.443
M25.78 Osteophyte (Other)	0.556	0.444
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.556	0.444
E11.7 With multiple complications	0.554	0.446
M23.0 Cystic meniscus	0.553	0.447
U80.8 Agent resistant to other penicillin-related antibiotic	0.552	0.448
S70.0 Contusion of hip	0.552	0.448
M45 Ankylosing spondylitis	0.552	0.448
M60-M63 Disorders of muscles	0.551	0.449
M48.0 Spinal stenosis	0.550	0.450
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.550	0.450
T90.9 Sequelae of unspecified injury of head	0.550	0.450
S68 Traumatic amputation of wrist and hand	0.550	0.450
S08 Traumatic amputation of part of head	0.549	0.450
S07 Crushing injury of head	0.549	0.450
S04 Injury of cranial nerves	0.549	0.450
S03 Dislocation, sprain and strain of joints and ligaments of head	0.549	0.450
M24.2 Disorder of ligament	0.549	0.450
M50.3 Other cervical disk degeneration	0.549	0.451
E50-E64 Other nutritional deficiencies	0.549	0.451
O90 Complications of the puerperium, not elsewhere classified	0.548	0.452
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.548	0.452
S92.9 Fracture of foot, unspecified	0.547	0.453
S92.7 Multiple fractures of foot	0.547	0.453
S92.4 Fracture of great toe	0.547	0.453
S31.8 Open wound of other and unspecified parts of abdomen	0.547	0.453
T01 Open wounds involving multiple body regions	0.547	0.453
M54.55 Low back pain (Thoracolumbar region)	0.546	0.454
M23.80 Other internal derangements of knee (Multiple sites)	0.545	0.454
M42 Spinal osteochondrosis	0.545	0.455
S72.1 Pertrochanteric fracture	0.545	0.455
M54.64 Pain in thoracic spine (Thoracic region)	0.544	0.456
M53.9 Dorsopathy, unspecified	0.543	0.457
M53.8 Other specified dorsopathies	0.543	0.457
M53.2 Spinal instabilities	0.543	0.457
M53.1 Cervicobrachial syndrome	0.543	0.457
M53.0 Cervicocranial syndrome	0.543	0.457
S42.4 Fracture of lower end of humerus	0.543	0.457
M30 Polyarteritis nodosa and related conditions	0.543	0.457
M31 Other necrotising vasculopathies	0.542	0.458
M54.47 Lumbago with sciatica (Lumbosacral region)	0.542	0.458
E11.3 With ophthalmic complications	0.541	0.459
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.540	0.459
M23.1 Discoid meniscus (congenital)	0.539	0.461
E87.2 Acidosis	0.539	0.461
K86.3 Pseudocyst of pancreas	0.539	0.461
S40.7 Multiple superficial injuries of shoulder and upper arm	0.538	0.462
S06.2 Diffuse brain injury	0.538	0.462
T90.2 Sequelae of fracture of skull and facial bones	0.537	0.463
S02.6 Fracture of mandible	0.537	0.463
E11.1 With ketoacidosis	0.537	0.463
E87.3 Alkalosis	0.537	0.463
E88 Other metabolic disorders	0.536	0.463
S06.6 Traumatic subarachnoid haemorrhage	0.536	0.464
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.536	0.464
S90.9 Superficial injury of ankle and foot, unspecified	0.536	0.464
E87.4 Mixed disorder of acid-base balance	0.535	0.465
O16 Unspecified maternal hypertension	0.535	0.465
T09 Other injuries of spine and trunk, level unspecified	0.535	0.465
M23.49 Loose body in knee-Unspec lig/men	0.535	0.465
E22 Hyperfunction of pituitary gland	0.534	0.466
S90.7 Multiple superficial injuries of ankle and foot	0.534	0.466
S90.2 Contusion of toe(s) with damage to nail	0.534	0.466
S90.1 Contusion of toe(s) without damage to nail	0.534	0.466
S90.0 Contusion of ankle	0.534	0.466
M47.1 Other spondylosis with myelopathy	0.533	0.466
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.533	0.466
M06.9 Rheumatoid arthritis, unspecified	0.533	0.467
T90.8 Sequelae of other specified injuries of head	0.532	0.467
O85 Puerperal sepsis	0.532	0.468
M54.96 Dorsalgia, unspecified (Lumbar region)	0.532	0.468
S72.00 Fracture of neck of femur (closed)	0.530	0.469
K77 Liver disorders in diseases classified elsewhere	0.530	0.470
K71 Toxic liver disease	0.530	0.470
M43.0 Spondylolysis	0.530	0.470
M40 Kyphosis and lordosis	0.530	0.470
U80.1 Methicillin resistant agent	0.530	0.470
S92.3 Fracture of metatarsal bone	0.530	0.470
S02.3 Fracture of orbital floor	0.529	0.471
S02.7 Multiple fractures involving skull and facial bones	0.527	0.473
S42.0 Fracture of clavicle	0.527	0.473
S72.2 Subtrochanteric fracture	0.527	0.473
S02.8 Fractures of other skull and facial bones	0.526	0.474
E11.6 With other specified complications	0.526	0.474
M24.8 Other specific joint derangements, not elsewhere classified	0.526	0.474
T93.8 Sequelae of other specified injuries of lower limb	0.526	0.474
M34.1 CR(E)ST syndrome	0.524	0.476
K86.0 Alcohol-induced chronic pancreatitis	0.522	0.478
S91 Open wound of ankle and foot	0.522	0.478
T90.1 Sequelae of open wound of head	0.522	0.478
M91 Juvenile osteochondrosis of hip and pelvis	0.522	0.478
E74 Other disorders of carbohydrate metabolism	0.522	0.478
S02.9 Fracture of skull and facial bones, part unspecified	0.520	0.480
S20 Superficial injury of thorax	0.520	0.480
M92.7 Juvenile osteochondrosis of metatarsus	0.520	0.480
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.519	0.481
T19 Foreign body in genito-urinary tract	0.519	0.481
M43.9 Deforming dorsopathy, unspecified	0.518	0.481
M43.8 Other specified deforming dorsopathies	0.518	0.481
M43.6 Torticollis	0.518	0.481
M43.5 Other recurrent vertebral subluxation	0.518	0.481
M43.4 Other recurrent atlantoaxial subluxation	0.518	0.481
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.518	0.481
M43.2 Other fusion of spine	0.518	0.481
E10.4 With neurological complications	0.518	0.482
M24.09 Loose body in joint (Site unspecified)	0.518	0.482
M24.08 Loose body in joint (Other)	0.518	0.482
M24.06 Loose body in joint-Lower leg	0.518	0.482
M24.05 Loose body in joint (Pelvic region and thigh)	0.518	0.482
M24.04 Loose body in joint (Hand)	0.518	0.482
M24.03 Loose body in joint (Forearm)	0.518	0.482
M24.01 Loose body in joint (Shoulder region)	0.518	0.482
M24.00 Loose body in joint (Multiple sites)	0.518	0.482
M54.49 Lumbago with sciatica (Site unspecified)	0.518	0.482
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.517	0.483
T20 Burn and corrosion of head and neck	0.517	0.483
E40-E46 Malnutrition	0.517	0.483
E27 Other disorders of adrenal gland	0.516	0.483
U80.0 Penicillin resistant agent	0.516	0.483
K75 Other inflammatory liver diseases	0.516	0.484
M23.87 Other internal derangements of knee (Capsular ligament)	0.516	0.484
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.516	0.484
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.516	0.484
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.516	0.484
O87 Venous complications in the puerperium	0.516	0.484
S70.8 Other superficial injuries of hip and thigh	0.516	0.484
S70.7 Multiple superficial injuries of hip and thigh	0.516	0.484
T11 Other injuries of upper limb, level unspecified	0.515	0.485
T91.1 Sequelae of fracture of spine	0.515	0.485
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486
K87.1 Disorders of pancreas in diseases classified elsewhere	0.514	0.486
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.514	0.486
S72.9 Fracture of femur, part unspecified	0.514	0.486
S72.8 Fractures of other parts of femur	0.514	0.486
S72.7 Multiple fractures of femur	0.514	0.486
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.514	0.486
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.513	0.486
U51.0 Not Previously admitted to a psyciatric hospital	0.513	0.487
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.512	0.487
S02.20 Fracture of nasal bones (closed)	0.512	0.488
T68 Hypothermia	0.511	0.489
S27 Injury of other and unspecified intrathoracic organs	0.511	0.489
M48.5 Collapsed vertebra, not elsewhere classified	0.510	0.490
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.509	0.491
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.509	0.491
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.508	0.492
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.508	0.492
M54.44 Lumbago with sciatica-Thoracic	0.508	0.492
M54.43 Lumbago with sciatica-Cervicothoracic	0.508	0.492
M54.42 Lumbago with sciatica-Cervical	0.508	0.492
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.508	0.492
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.508	0.492
U50 Level of care administered to neonates	0.508	0.492
U07 Emergency use of U07	0.508	0.492
U06 Emergency use of U06	0.508	0.492
U04 Severe acute respiratory syndrome [SARS]	0.508	0.492
U52 First in a series of a regular day/night admissions	0.508	0.492
E78.1 Pure hyperglyceridaemia	0.507	0.493
T17 Foreign body in respiratory tract	0.507	0.493
T14 Injury of unspecified body region	0.507	0.493
E13.9 Without complications	0.507	0.493
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.507	0.493
S63.1 Dislocation finger	0.506	0.493
S63.7 Sprain and strain of other and unspecified parts of hand	0.506	0.493
S63.5 Sprain and strain of wrist	0.506	0.493
S63.3 Traumatic rupture of ligament of wrist and carpus	0.506	0.493
S63.2 Multiple dislocations of fingers	0.506	0.493
S63.0 Dislocation of wrist	0.506	0.493
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.506	0.494
O92 Other disorders of breast and lactation associated with childbirth	0.506	0.494
O86.0 Infection of obstetric surgical wound	0.506	0.494
M47.92 Spondylosis, unspecified (Cervical region)	0.505	0.495
S02.00 Fracture of vault of skull (closed)	0.505	0.495
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.504	0.496
E10.7 With multiple complications	0.504	0.496
E10.6 With other specified complications	0.504	0.496
E10.0 With coma	0.504	0.496
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.504	0.496
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.503	0.496
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.503	0.497
T94.1 Sequelae of injuries, not specified by body region	0.503	0.497
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.503	0.497
S31.5 Open wound of other and unspecified external genital organs	0.503	0.497
S31.4 Open wound of vagina and vulva	0.503	0.497
S31.3 Open wound of scrotum and testes	0.503	0.497
S31.2 Open wound of penis	0.503	0.497

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations