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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6858365
log Bayes Factor = 0.381368
Chromosome 4   position 12,172,669  (GRCh37) Explore rs6858365 on Ensembl!
Variant rs6858365 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
0.562 0.438 0.000
# Top node
0.560 0.440 0.000
Chapter V Mental and behavioural disorders
0.559 0.441 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.557 0.443 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.557 0.443 0.000
M50-M54 Other dorsopathies
0.551 0.449 0.000
M54 Dorsalgia
0.549 0.451 0.000
O60-O75 Complications of labour and delivery
0.546 0.454 0.000
Chapter VIII Diseases of the ear and mastoid process
0.533 0.467 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.532 0.468 0.000
M05-M14 Inflammatory polyarthropathies
0.531 0.469 0.000
M65-M68 Disorders of synovium and tendon
0.525 0.475 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.524 0.476 0.000
O70 Perineal laceration during delivery
0.524 0.476 0.000
S00-S09 Injuries to the head
0.522 0.478 0.000
S40-S49 Injuries to the shoulder and upper arm
0.514 0.486 0.000
F41 Other anxiety disorders
0.506 0.494 0.000
Chapter I Certain infectious and parasitic diseases
0.501 0.499 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.499 0.501 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.496 0.503 0.000
M54.5 Low back pain
0.495 0.505 0.000
O70.0 First degree perineal laceration during delivery
0.493 0.507 0.000
O80-O84 Delivery
0.492 0.508 0.000
M54.9 Dorsalgia, unspecified
0.490 0.510 0.000
M54.3 Sciatica
0.490 0.510 0.000
B95-B98 Bacterial, viral and other infectious agents
0.489 0.511 0.000
S20-S29 Injuries to the thorax
0.488 0.512 0.000
F30-F39 Mood [affective] disorders
0.487 0.513 0.000
S70-S79 Injuries to the hip and thigh
0.485 0.515 0.000
M06 Other rheumatoid arthritis
0.484 0.516 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.484 0.516 0.000
M67 Other disorders of synovium and tendon
0.478 0.522 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.477 0.523 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.476 0.524 0.000
S01 Open wound of head
0.476 0.524 0.000
M10 Gout
0.474 0.526 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.473 0.527 0.000
H65-H75 Diseases of middle ear and mastoid
0.473 0.527 0.000
F43 Reaction to severe stress, and adjustment disorders
0.468 0.532 0.000
M54.2 Cervicalgia
0.457 0.543 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.457 0.543 0.000
O80 Single spontaneous delivery
0.457 0.543 0.000
S00 Superficial injury of head
0.454 0.546 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.453 0.547 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.453 0.547 0.000
H80-H83 Diseases of inner ear
0.451 0.549 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.451 0.549 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.448 0.552 0.000
M54.39 Sciatica (Site unspecified)
0.447 0.553 0.000
F41.2 Mixed anxiety and depressive disorder
0.446 0.554 0.000
M50 Cervical disk disorders
0.446 0.554 0.000
O48 Prolonged pregnancy
0.446 0.554 0.000
M06.9 Rheumatoid arthritis, unspecified
0.445 0.555 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.444 0.555 0.000
M67.8 Other specified disorders of synovium and tendon
0.444 0.556 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.443 0.557 0.000
H60-H62 Diseases of external ear
0.443 0.557 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.442 0.558 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.440 0.560 0.000
M65 Synovitis and tenosynovitis
0.439 0.560 0.000
M70-M79 Other soft tissue disorders
0.438 0.562 0.000
M54.4 Lumbago with sciatica
0.436 0.564 0.000
T66-T78 Other and unspecified effects of external causes
0.436 0.564 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.435 0.565 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.435 0.565 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.435 0.565 0.000
M10.9 Gout, unspecified
0.434 0.566 0.000
F99-F99 Unspecified mental disorder
0.431 0.569 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.430 0.570 0.000
M54.56 Low back pain (Lumbar region)
0.429 0.571 0.000
S01.0 Open wound of scalp
0.427 0.573 0.000
O80.0 Spontaneous vertex delivery
0.426 0.574 0.000
S90-S99 Injuries to the ankle and foot
0.426 0.574 0.000
O70.1 Second degree perineal laceration during delivery
0.424 0.576 0.000
S05 Injury of eye and orbit
0.423 0.577 0.000
F43.2 Adjustment disorders
0.423 0.577 0.000
M14 Arthropathies in other diseases classified elsewhere
0.422 0.578 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.421 0.579 0.000
S10-S19 Injuries to the neck
0.420 0.580 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.420 0.580 0.000
F29 Unspecified nonorganic psychosis
0.419 0.581 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.418 0.582 0.000
M86-M90 Other osteopathies
0.417 0.583 0.000
H83 Other diseases of inner ear
0.417 0.583 0.000
O85-O92 Complications predominantly related to the puerperium
0.416 0.583 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.416 0.584 0.000
H72 Perforation of tympanic membrane
0.415 0.585 0.000
M60-M63 Disorders of muscles
0.414 0.585 0.000
M54.57 Low back pain (Lumbosacral region)
0.414 0.586 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.413 0.587 0.000
F33 Recurrent depressive disorder
0.412 0.588 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.411 0.588 0.000
M91-M94 Chondropathies
0.411 0.589 0.000
B99-B99 Other infectious diseases
0.411 0.589 0.000
M40-M43 Deforming dorsopathies
0.411 0.589 0.000
F41.9 Anxiety disorder, unspecified
0.410 0.590 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.407 0.593 0.000
F60-F69 Disorders of adult personality and behaviour
0.406 0.594 0.000
S06 Intracranial injury
0.405 0.595 0.000
S42 Fracture of shoulder and upper arm
0.405 0.595 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.404 0.596 0.000
S27 Injury of other and unspecified intrathoracic organs
0.403 0.597 0.000
F31 Bipolar affective disorder
0.403 0.597 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.403 0.597 0.000
F30 Manic episode
0.403 0.597 0.000
O62 Abnormalities of forces of labour
0.403 0.597 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.401 0.598 0.000
S00.3 Superficial injury of nose
0.401 0.599 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.401 0.599 0.000
F70-F79 Mental retardation
0.401 0.599 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.400 0.599 0.000
M54.1 Radiculopathy
0.400 0.600 0.000
T33-T35 Frostbite
0.400 0.600 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.400 0.600 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.400 0.600 0.000
T00-T07 Injuries involving multiple body regions
0.400 0.600 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.400 0.600 0.000
M00-M03 Infectious arthropathies
0.399 0.601 0.000
S70 Superficial injury of hip and thigh
0.399 0.601 0.000
M79.6 Pain in limb
0.398 0.602 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.397 0.603 0.000
M66 Spontaneous rupture of synovium and tendon
0.396 0.604 0.000
O70.9 Perineal laceration during delivery, unspecified
0.396 0.604 0.000
M53 Other dorsopathies, not elsewhere classified
0.395 0.605 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.395 0.605 0.000
M54.8 Other dorsalgia
0.394 0.606 0.000
M54.6 Pain in thoracic spine
0.394 0.606 0.000
M54.0 Panniculitis affecting regions of neck and back
0.394 0.606 0.000
H83.0 Labyrinthitis
0.393 0.607 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.392 0.608 0.000
M07 Psoriatic and enteropathic arthropathies
0.392 0.608 0.000
O74 Complications of anaesthesia during labour and delivery
0.392 0.608 0.000
O71 Other obstetric trauma
0.392 0.608 0.000
O66 Other obstructed labour
0.392 0.608 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.392 0.608 0.000
O61 Failed induction of labour
0.392 0.608 0.000
O60 Preterm delivery
0.392 0.608 0.000
O47 False labour
0.391 0.609 0.000
S40 Superficial injury of shoulder and upper arm
0.391 0.609 0.000
O70.2 Third degree perineal laceration during delivery
0.387 0.612 0.000
F80-F89 Disorders of psychological development
0.387 0.613 0.000
S43.0 Dislocation of shoulder joint
0.387 0.613 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.386 0.614 0.000
H90-H95 Other disorders of ear
0.386 0.614 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.386 0.614 0.000
H61 Other disorders of external ear
0.385 0.615 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.385 0.615 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.384 0.616 0.000
S01.1 Open wound of eyelid and periocular area
0.384 0.616 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.383 0.617 0.000
M54.59 Low back pain (Site unspecified)
0.383 0.617 0.000
M10.99 Gout, unspecified (Site unspecified)
0.382 0.618 0.000
M05 Seropositive rheumatoid arthritis
0.382 0.618 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.381 0.619 0.000
F48 Other neurotic disorders
0.381 0.619 0.000
F44 Dissociative [conversion] disorders
0.381 0.619 0.000
F42 Obsessive-compulsive disorder
0.381 0.619 0.000
F25 Schizoaffective disorders
0.381 0.619 0.000
M12 Other specific arthropathies
0.380 0.619 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.380 0.619 0.000
M08 Juvenile arthritis
0.380 0.619 0.000
T63 Toxic effect of contact with venomous animals
0.380 0.620 0.000
H71 Cholesteatoma of middle ear
0.379 0.621 0.000
T51 Toxic effect of alcohol
0.379 0.621 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.378 0.622 0.000
M50.3 Other cervical disk degeneration
0.378 0.622 0.000
S80-S89 Injuries to the knee and lower leg
0.377 0.623 0.000
T79-T79 Certain early complications of trauma
0.377 0.623 0.000
O36 Maternal care for other known or suspected foetal problems
0.376 0.624 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.376 0.624 0.000
S20 Superficial injury of thorax
0.376 0.624 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.376 0.624 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.376 0.624 0.000
O97 Death from sequelae of direct obstetric causes
0.376 0.624 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.376 0.624 0.000
O95 Obstetric death of unspecified cause
0.376 0.624 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.376 0.624 0.000
O70.3 Fourth degree perineal laceration during delivery
0.375 0.624 0.000
O42 Premature rupture of membranes
0.375 0.625 0.000
S08 Traumatic amputation of part of head
0.375 0.625 0.000
S07 Crushing injury of head
0.375 0.625 0.000
S04 Injury of cranial nerves
0.375 0.625 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.375 0.625 0.000
M06.4 Inflammatory polyarthropathy
0.374 0.626 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.373 0.627 0.000
S29 Other and unspecified injuries of thorax
0.372 0.627 0.000
O73 Retained placenta and membranes, without haemorrhage
0.372 0.628 0.000
F10.2 Dependence syndrome
0.372 0.628 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.371 0.629 0.000
S72 Fracture of femur
0.371 0.629 0.000
S71 Open wound of hip and thigh
0.369 0.631 0.000
O16 Unspecified maternal hypertension
0.369 0.631 0.000
S48 Traumatic amputation of shoulder and upper arm
0.369 0.631 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.369 0.631 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.369 0.631 0.000
S44 Injury of nerves at shoulder and upper arm level
0.369 0.631 0.000
S41 Open wound of shoulder and upper arm
0.369 0.631 0.000
S47 Crushing injury of shoulder and upper arm
0.369 0.631 0.000
T59 Toxic effect of other gases, fumes and vapours
0.367 0.632 0.000
M11 Other crystal arthropathies
0.367 0.632 0.000
M54.22 Cervicalgia (Cervical region)
0.367 0.633 0.000
F23 Acute and transient psychotic disorders
0.367 0.633 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.367 0.633 0.000
S79 Other and unspecified injuries of hip and thigh
0.367 0.633 0.000
S50-S59 Injuries to the elbow and forearm
0.366 0.634 0.000
S00.8 Superficial injury of other parts of head
0.366 0.634 0.000
S01.5 Open wound of lip and oral cavity
0.365 0.635 0.000
F03 Unspecified dementia
0.364 0.636 0.000
F41.8 Other specified anxiety disorders
0.363 0.637 0.000
F41.3 Other mixed anxiety disorders
0.363 0.637 0.000
M54.29 Cervicalgia-Site unspe
0.362 0.637 0.000
M80-M85 Disorders of bone density and structure
0.362 0.638 0.000
Chapter XXII Codes for special purposes
0.361 0.639 0.000
T31 Burns classified according to extent of body surface involved
0.361 0.639 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.359 0.640 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.359 0.641 0.000
F41.1 Generalised anxiety disorder
0.359 0.641 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.359 0.641 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.359 0.641 0.000
B65-B83 Helminthiases
0.359 0.641 0.000
B50-B64 Protozoal diseases
0.359 0.641 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.359 0.641 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.359 0.641 0.000
A75-A79 Rickettsioses
0.359 0.641 0.000
A70-A74 Other diseases caused by chlamydiae
0.359 0.641 0.000
A65-A69 Other spirochaetal diseases
0.359 0.641 0.000
A20-A28 Certain zoonotic bacterial diseases
0.359 0.641 0.000
A15-A19 Tuberculosis
0.359 0.641 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.359 0.641 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.358 0.642 0.000
O45 Premature separation of placenta [abruptio placentae]
0.358 0.642 0.000
O44 Placenta praevia
0.358 0.642 0.000
O43 Placental disorders
0.358 0.642 0.000
O41 Other disorders of amniotic fluid and membranes
0.358 0.642 0.000
O33 Maternal care for known or suspected disproportion
0.358 0.642 0.000
O31 Complications specific to multiple gestation
0.358 0.642 0.000
O40 Polyhydramnios
0.358 0.642 0.000
M79.64 Pain in limb (Hand)
0.357 0.643 0.000
S01.8 Open wound of other parts of head
0.357 0.643 0.000
T92 Sequelae of injuries of upper limb
0.356 0.644 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.356 0.644 0.000
M54.55 Low back pain (Thoracolumbar region)
0.355 0.645 0.000
M54.54 Low back pain-Thoracic
0.355 0.645 0.000
M54.53 Low back pain-Cervicothoracic
0.355 0.645 0.000
M54.52 Low back pain-Cervical
0.355 0.645 0.000
M54.51 Low back pain-Occipit-atl-axl
0.355 0.645 0.000
M54.50 Low back pain (Multiple sites in spine)
0.355 0.645 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.355 0.645 0.000
O84 Multiple delivery
0.353 0.647 0.000
O83 Other assisted single delivery
0.353 0.647 0.000
O81 Single delivery by forceps and vacuum extractor
0.353 0.647 0.000
Chapter X Diseases of the respiratory system
0.353 0.647 0.000
O80.9 Single spontaneous delivery, unspecified
0.353 0.647 0.000
M54.36 Sciatica (Lumbar region)
0.353 0.647 0.000
S05.1 Contusion of eyeball and orbital tissues
0.352 0.648 0.000
A30-A49 Other bacterial diseases
0.352 0.648 0.000
S00.7 Multiple superficial injuries of head
0.352 0.648 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.352 0.648 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.352 0.648 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.352 0.648 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.352 0.648 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.352 0.648 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.352 0.648 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.352 0.648 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.352 0.648 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.351 0.649 0.000
M54.37 Sciatica (Lumbosacral region)
0.351 0.649 0.000
M54.35 Sciatica (Thoracolumbar region)
0.351 0.649 0.000
M54.34 Sciatica-Thoracic
0.351 0.649 0.000
M54.33 Sciatica-Cervicothoracic
0.351 0.649 0.000
M54.32 Sciatica-Cervical
0.351 0.649 0.000
M54.31 Sciatica-Occipit-atl-axl
0.351 0.649 0.000
M54.30 Sciatica (Multiple sites in spine)
0.351 0.649 0.000
B15-B19 Viral hepatitis
0.351 0.649 0.000
A80-A89 Viral infections of the central nervous system
0.350 0.649 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.350 0.650 0.000
S26 Injury of heart
0.350 0.650 0.000
S25 Injury of blood vessels of thorax
0.350 0.650 0.000
S24 Injury of nerves and spinal cord at thorax level
0.350 0.650 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.350 0.650 0.000
S21 Open wound of thorax
0.350 0.650 0.000
H65 Nonsuppurative otitis media
0.350 0.650 0.000
Chapter XIV Diseases of the genitourinary system
0.350 0.650 0.000
F38 Other mood [affective] disorders
0.349 0.650 0.000
F34 Persistent mood [affective] disorders
0.349 0.650 0.000
F39 Unspecified mood [affective] disorder
0.349 0.650 0.000
H74 Other disorders of middle ear and mastoid
0.349 0.651 0.000
M79.7 Fibromyalgia
0.349 0.651 0.000
T78 Adverse effects, not elsewhere classified
0.349 0.651 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.349 0.651 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.349 0.651 0.000
N30-N39 Other diseases of urinary system
0.349 0.651 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.348 0.652 0.000
F31.9 Bipolar affective disorder, unspecified
0.348 0.652 0.000
S78 Traumatic amputation of hip and thigh
0.348 0.652 0.000
S77 Crushing injury of hip and thigh
0.348 0.652 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.348 0.652 0.000
S75 Injury of blood vessels at hip and thigh level
0.348 0.652 0.000
S74 Injury of nerves at hip and thigh level
0.348 0.652 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.348 0.652 0.000
M06.8 Other specified rheumatoid arthritis
0.347 0.653 0.000
M06.3 Rheumatoid nodule
0.347 0.653 0.000
M06.2 Rheumatoid bursitis
0.347 0.653 0.000
M06.1 Adult-onset Still's disease
0.347 0.653 0.000
B99 Other and unspecified infectious diseases
0.347 0.653 0.000
M79.67 Pain in limb (Ankle and foot)
0.346 0.654 0.000
S01.3 Open wound of ear
0.346 0.654 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.344 0.656 0.000
M14.6 Neuropathic arthropathy
0.344 0.656 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.344 0.656 0.000
F45 Somatoform disorders
0.344 0.656 0.000
H90 Conductive and sensorineural hearing loss
0.344 0.656 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.343 0.657 0.000
M67.4 Ganglion
0.343 0.657 0.000
M67.3 Transient synovitis
0.343 0.657 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.343 0.657 0.000
M67.1 Other contracture of tendon (sheath)
0.343 0.657 0.000
M67.0 Short Achilles tendon (acquired)
0.343 0.657 0.000
T65 Toxic effect of other and unspecified substances
0.342 0.658 0.000
T62 Toxic effect of other noxious substances eaten as food
0.342 0.658 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.342 0.658 0.000
T60 Toxic effect of pesticides
0.342 0.658 0.000
T57 Toxic effect of other inorganic substances
0.342 0.658 0.000
T56 Toxic effect of metals
0.342 0.658 0.000
T54 Toxic effect of corrosive substances
0.342 0.658 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.342 0.658 0.000
T52 Toxic effect of organic solvents
0.342 0.658 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.342 0.658 0.000
T58 Toxic effect of carbon monoxide
0.342 0.658 0.000
T55 Toxic effect of soaps and detergents
0.342 0.658 0.000
F30.9 Manic episode, unspecified
0.342 0.658 0.000
S27.0 Traumatic pneumothorax
0.342 0.658 0.000
F28 Other nonorganic psychotic disorders
0.342 0.658 0.000
F24 Induced delusional disorder
0.342 0.658 0.000
F21 Schizotypal disorder
0.342 0.658 0.000
S01.7 Multiple open wounds of head
0.342 0.658 0.000
S01.4 Open wound of cheek and temporomandibular area
0.342 0.658 0.000
S42.0 Fracture of clavicle
0.342 0.658 0.000
M10.4 Other secondary gout
0.340 0.660 0.000
M10.3 Gout due to impairment of renal function
0.340 0.660 0.000
M10.2 Drug-induced gout
0.340 0.660 0.000
M10.1 Lead-induced gout
0.340 0.660 0.000
M10.0 Idiopathic gout
0.340 0.660 0.000
S32 Fracture of lumbar spine and pelvis
0.340 0.660 0.000
S00.0 Superficial injury of scalp
0.340 0.660 0.000
M06.0 Seronegative rheumatoid arthritis
0.340 0.660 0.000
F99 Mental disorder, not otherwise specified
0.340 0.660 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.339 0.660 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.339 0.660 0.000
Chapter II Neoplasms
0.339 0.661 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.339 0.661 0.000
H70 Mastoiditis and related conditions
0.339 0.661 0.000
H69 Other disorders of Eustachian tube
0.339 0.661 0.000
H68 Eustachian salpingitis and obstruction
0.339 0.661 0.000
H67 Otitis media in diseases classified elsewhere
0.339 0.661 0.000
O63 Long labour
0.339 0.661 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.338 0.662 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.338 0.662 0.000
H66 Suppurative and unspecified otitis media
0.338 0.662 0.000
M79.60 Pain in limb (Multiple sites)
0.337 0.663 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.337 0.663 0.000
F43.9 Reaction to severe stress, unspecified
0.336 0.664 0.000
F43.8 Other reactions to severe stress
0.336 0.664 0.000
F43.1 Posttraumatic stress disorder
0.336 0.664 0.000
F43.0 Acute stress reaction
0.336 0.664 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.335 0.665 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.335 0.665 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.335 0.665 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.334 0.666 0.000
F33.9 Recurrent depressive disorder, unspecified
0.334 0.666 0.000
F10.3 Withdrawal state
0.333 0.667 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.333 0.667 0.000
B35-B49 Mycoses
0.332 0.667 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.332 0.668 0.000
F22 Persistent delusional disorders
0.332 0.668 0.000
S70.8 Other superficial injuries of hip and thigh
0.332 0.668 0.000
S92 Fracture of foot, except ankle
0.332 0.668 0.000
D10-D36 Benign neoplasms
0.331 0.669 0.000
H61.2 Impacted cerumen
0.330 0.669 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.330 0.670 0.000
T90 Sequelae of injuries of head
0.330 0.670 0.000
Q60-Q64 Congenital malformations of the urinary system
0.330 0.670 0.000
M79.69 Pain in limb (Site unspecified)
0.329 0.671 0.000
D25 Leiomyoma of uterus
0.329 0.671 0.000
M50.2 Other cervical disk displacement
0.329 0.671 0.000
N30 Cystitis
0.329 0.671 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.328 0.672 0.000
M54.27 Cervicalgia-Lumbosacral
0.328 0.672 0.000
M54.26 Cervicalgia-Lumbar
0.328 0.672 0.000
M54.25 Cervicalgia-Thoracolumbar
0.328 0.672 0.000
M54.24 Cervicalgia-Thoracic
0.328 0.672 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.328 0.672 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.328 0.672 0.000
M54.20 Cervicalgia-Mult site
0.328 0.672 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.328 0.672 0.000
O80.8 Other single spontaneous delivery
0.328 0.672 0.000
O80.1 Spontaneous breech delivery
0.328 0.672 0.000
M79.5 Residual foreign body in soft tissue
0.326 0.674 0.000
J30-J39 Other diseases of upper respiratory tract
0.326 0.674 0.000
S00.5 Superficial injury of lip and oral cavity
0.325 0.674 0.000
S00.4 Superficial injury of ear
0.325 0.674 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.325 0.674 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.325 0.675 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.325 0.675 0.000
O64.5 Obstructed labour due to compound presentation
0.325 0.675 0.000
O64.4 Obstructed labour due to shoulder presentation
0.325 0.675 0.000
O64.3 Obstructed labour due to brow presentation
0.325 0.675 0.000
O64.2 Obstructed labour due to face presentation
0.325 0.675 0.000
O64.1 Obstructed labour due to breech presentation
0.325 0.675 0.000
N39 Other disorders of urinary system
0.325 0.675 0.000
O46.9 Antepartum haemorrhage, unspecified
0.324 0.676 0.000
T14 Injury of unspecified body region
0.323 0.676 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.323 0.677 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.323 0.677 0.000
Q80-Q89 Other congenital malformations
0.323 0.677 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.323 0.677 0.000
Q35-Q37 Cleft lip and cleft palate
0.323 0.677 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.323 0.677 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.323 0.677 0.000
M10.96 Gout, unspecified (Lower leg)
0.323 0.677 0.000
M65.3 Trigger finger
0.322 0.677 0.000
O69.8 Labour and delivery complicated by other cord complications
0.322 0.678 0.000
M77 Other enthesopathies
0.322 0.678 0.000
M50.0 Cervical disk disorder with myelopathy
0.322 0.678 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.321 0.678 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.321 0.678 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.321 0.678 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.321 0.678 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.321 0.678 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.321 0.678 0.000
F11 Mental and behavioural disorders due to use of opioids
0.321 0.678 0.000
H72.8 Other perforations of tympanic membrane
0.321 0.679 0.000
N39.0 Urinary tract infection, site not specified
0.321 0.679 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.321 0.679 0.000
S10 Superficial injury of neck
0.321 0.679 0.000
J30 Vasomotor and allergic rhinitis
0.321 0.679 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.320 0.679 0.000
S01.2 Open wound of nose
0.320 0.679 0.000
M50.9 Cervical disk disorder, unspecified
0.320 0.680 0.000
M50.8 Other cervical disk disorders
0.320 0.680 0.000
D25.9 Leiomyoma of uterus, unspecified
0.320 0.680 0.000
O30 Multiple gestation
0.319 0.681 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.319 0.681 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.319 0.681 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.319 0.681 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.319 0.681 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.319 0.681 0.000
S01.9 Open wound of head, part unspecified
0.319 0.681 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.319 0.681 0.000
F02 Dementia in other diseases classified elsewhere
0.319 0.681 0.000
F01 Vascular dementia
0.319 0.681 0.000
F09 Unspecified organic or symptomatic mental disorder
0.319 0.681 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.319 0.681 0.000
Q00-Q07 Congenital malformations of the nervous system
0.318 0.681 0.000
S00.1 Contusion of eyelid and periocular area
0.318 0.682 0.000
J30.1 Allergic rhinitis due to pollen
0.318 0.682 0.000
M79.1 Myalgia
0.318 0.682 0.000
T32 Corrosions classified according to extent of body surface involved
0.318 0.682 0.000
T30 Burn and corrosion, body region unspecified
0.318 0.682 0.000
T29 Burns and corrosions of multiple body regions
0.318 0.682 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.318 0.682 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.317 0.683 0.000
M71 Other bursopathies
0.316 0.684 0.000
F40 Phobic anxiety disorders
0.316 0.684 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.315 0.685 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.315 0.685 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.315 0.685 0.000
S43.4 Sprain and strain of shoulder joint
0.315 0.685 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.315 0.685 0.000
S43.2 Dislocation of sternoclavicular joint
0.315 0.685 0.000
S43.1 Dislocation of acromioclavicular joint
0.315 0.685 0.000
M65.8 Other synovitis and tenosynovitis
0.315 0.685 0.000
M65.2 Calcific tendinitis
0.315 0.685 0.000
M65.1 Other infective (teno)synovitis
0.315 0.685 0.000
M65.0 Abscess of tendon sheath
0.315 0.685 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.315 0.685 0.000
F00 Dementia in Alzheimer's disease
0.315 0.685 0.000
N32 Other disorders of bladder
0.315 0.685 0.000
S02 Fracture of skull and facial bones
0.314 0.685 0.000
M76 Enthesopathies of lower limb, excluding foot
0.314 0.686 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.314 0.686 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.313 0.687 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.313 0.687 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.313 0.687 0.000
M54.44 Lumbago with sciatica-Thoracic
0.313 0.687 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.313 0.687 0.000
M54.42 Lumbago with sciatica-Cervical
0.313 0.687 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.313 0.687 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.313 0.687 0.000
T75 Effects of other external causes
0.313 0.687 0.000
T74 Maltreatment syndromes
0.313 0.687 0.000
T73 Effects of other deprivation
0.313 0.687 0.000
T70 Effects of air pressure and water pressure
0.313 0.687 0.000
T69 Other effects of reduced temperature
0.313 0.687 0.000
T67 Effects of heat and light
0.313 0.687 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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