TreeWAS – Variant ID: rs6901084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
E10.1 With ketoacidosis	0.000	0.000	1.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E16.2 Hypoglycaemia, unspecified	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.000	1.000
E16 Other disorders of pancreatic internal secretion	0.000	0.000	1.000
L40 Psoriasis	0.999	0.001	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.995	0.005	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.007	0.993
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.009	0.991
E00-E07 Disorders of thyroid gland	0.000	0.009	0.991
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.989	0.011	0.000
E10.2 With renal complications	0.000	0.012	0.988
M06.3 Rheumatoid nodule	0.979	0.021	0.000
E10.4 With neurological complications	0.000	0.022	0.978
M07 Psoriatic and enteropathic arthropathies	0.965	0.035	0.000
E14 Unspecified diabetes mellitus	0.000	0.046	0.954
M07.3 Other psoriatic arthropathies	0.944	0.056	0.000
M06.0 Seronegative rheumatoid arthritis	0.943	0.057	0.000
E40-E46 Malnutrition	0.000	0.065	0.935
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.928	0.072	0.000
E50-E64 Other nutritional deficiencies	0.000	0.081	0.919
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.914	0.086	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.112	0.888
E14.3 With ophthalmic complications	0.000	0.118	0.882
M07.39 Other psoriatic arthropathies (Site unspecified)	0.880	0.120	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.121	0.879
M06.32 Rheumatoid nodule (Upper arm)	0.875	0.125	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.135	0.865
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.865	0.135	0.000
L40.0 Psoriasis vulgaris	0.858	0.142	0.000
M06.34 Rheumatoid nodule (Hand)	0.856	0.144	0.000
E14.8 With unspecified complications	0.000	0.152	0.848
E55 Vitamin D deficiency	0.000	0.153	0.847
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.844	0.156	0.000
E10.5 With peripheral circulatory complications	0.000	0.160	0.840
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.829	0.171	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.173	0.827
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.822	0.178	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.821	0.179	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.809	0.191	0.000
L40.1 Generalised pustular psoriasis	0.808	0.192	0.000
M05.8 Other seropositive rheumatoid arthritis	0.808	0.192	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.802	0.198	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.205	0.795
M14 Arthropathies in other diseases classified elsewhere	0.795	0.205	0.000
M06.33 Rheumatoid nodule (Forearm)	0.789	0.211	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.788	0.212	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.212	0.788
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.787	0.213	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.784	0.216	0.000
E10.8 With unspecified complications	0.000	0.218	0.782
M06.4 Inflammatory polyarthropathy	0.781	0.219	0.000
E14.2 Withrenal complications	0.000	0.223	0.777
M06.37 Rheumatoid nodule (Ankle and foot)	0.776	0.224	0.000
M08 Juvenile arthritis	0.775	0.225	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.772	0.228	0.000
E10.7 With multiple complications	0.000	0.228	0.772
M05.1 Rheumatoid lung disease	0.771	0.229	0.000
K90 Intestinal malabsorption	0.000	0.233	0.767
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.761	0.239	0.000
E14.6 With other specified complications	0.000	0.242	0.757
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.757	0.243	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.757	0.243	0.000
E10.6 With other specified complications	0.000	0.252	0.748
E10.0 With coma	0.000	0.253	0.747
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.743	0.256	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.743	0.257	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.742	0.258	0.000
M05.2 Rheumatoid vasculitis	0.742	0.258	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.737	0.263	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.265	0.735
L40.3 Pustulosis palmaris et plantaris	0.735	0.265	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.270	0.730
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.724	0.276	0.000
L40.8 Other psoriasis	0.719	0.281	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.000	0.283	0.717
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.283	0.717
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.283	0.717
E16.4 Abnormal secretion of gastrin	0.000	0.283	0.717
E16.3 Increased secretion of glucagon	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.717	0.283	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.716	0.284	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.285	0.715
E58 Dietary calcium deficiency	0.000	0.287	0.713
E05.5 Thyroid crisis or storm	0.000	0.289	0.711
E05.4 Thyrotoxicosis factitia	0.000	0.289	0.711
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.289	0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.290	0.710
E00 Congenital iodine-deficiency syndrome	0.000	0.290	0.710
E61 Deficiency of other nutrient elements	0.000	0.292	0.708
M07.30 Other psoriatic arthropathies (Multiple sites)	0.704	0.296	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.702	0.298	0.000
M06.38 Rheumatoid nodule (Other)	0.702	0.298	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.702	0.298	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.702	0.298	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.299	0.701
M11 Other crystal arthropathies	0.700	0.300	0.000
L40.4 Guttate psoriasis	0.697	0.303	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.697	0.303	0.000
M12 Other specific arthropathies	0.694	0.306	0.000
M07.5 Arthropathy in ulcerative colitis	0.692	0.308	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.692	0.308	0.000
M07.2 Psoriatic spondylitis	0.692	0.308	0.000
M07.1 Arthritis mutilans	0.692	0.308	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.692	0.308	0.000
E14.9 Without complications	0.000	0.311	0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.687	0.313	0.000
E14.7 With multiple complications	0.000	0.316	0.684
E14.0 With coma	0.000	0.316	0.684
G36 Other acute disseminated demyelination	0.000	0.316	0.684
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.682	0.318	0.000
M07.38 Other psoriatic arthropathies (Other)	0.676	0.323	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.676	0.323	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.676	0.323	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.676	0.324	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.676	0.324	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.676	0.324	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.676	0.324	0.000
E51 Thiamine deficiency	0.000	0.326	0.673
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.327	0.673
M06.8 Other specified rheumatoid arthritis	0.671	0.329	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.330	0.670
E45 Retarded development following protein-energy malnutrition	0.000	0.330	0.670
E43 Unspecified severe protein-energy malnutrition	0.000	0.330	0.670
E42 Marasmic kwashiorkor	0.000	0.330	0.670
E41 Nutritional marasmus	0.000	0.330	0.670
E40 Kwashiorkor	0.000	0.330	0.670
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.334	0.666
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.662	0.338	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.341	0.659
E63 Other nutritional deficiencies	0.000	0.341	0.659
E50 Vitamin A deficiency	0.000	0.341	0.659
E60 Dietary zinc deficiency	0.000	0.341	0.659
E59 Dietary selenium deficiency	0.000	0.341	0.659
E54 Ascorbic acid deficiency	0.000	0.341	0.659
E52 Niacin deficiency [pellagra]	0.000	0.341	0.659
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.652	0.348	0.000
M07.6 Other enteropathic arthropathies	0.650	0.349	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.352	0.648
M14.6 Neuropathic arthropathy	0.648	0.352	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.644	0.356	0.000
E14.5 With peripheral circulatory complications	0.000	0.359	0.641
E13 Other specified diabetes mellitus	0.000	0.362	0.637
E16.1 Other hypoglycaemia	0.000	0.365	0.635
E56 Other vitamin deficiencies	0.000	0.368	0.632
E14.1 With ketoacidosis	0.000	0.389	0.611
M05.19 Rheumatoid lung disease (Site unspecified)	0.608	0.392	0.000
E55.0 Rickets, active	0.000	0.393	0.607
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.605	0.395	0.000
M13 Other arthritis	0.604	0.396	0.000
E53 Deficiency of other B group vitamins	0.000	0.396	0.604
D00-D09 In situ neoplasms	0.602	0.398	0.000
M08.0 Juvenile rheumatoid arthritis	0.600	0.400	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.406	0.594
G37.5 Concentric sclerosis [Balo]	0.000	0.407	0.593
G37.4 Subacute necrotising myelitis	0.000	0.407	0.593
G37.2 Central pontine myelinolysis	0.000	0.407	0.593
G37.1 Central demyelination of corpus callosum	0.000	0.407	0.593
G37.0 Diffuse sclerosis	0.000	0.407	0.593
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.593	0.407	0.000
E61.2 Magnesium deficiency	0.000	0.408	0.592
D06 Carcinoma in situ of cervix uteri	0.591	0.409	0.000
D04 Carcinoma in situ of skin	0.591	0.409	0.000
C44.7 Skin of lower limb, including hip	0.589	0.411	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.584	0.416	0.000
D06.9 Cervix, unspecified	0.580	0.420	0.000
E05.8 Other thyrotoxicosis	0.000	0.421	0.579
M05.88 Other seropositive rheumatoid arthritis (Other)	0.579	0.421	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.579	0.421	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.579	0.421	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.579	0.421	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.579	0.421	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.579	0.421	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.579	0.421	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.579	0.421	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.575	0.425	0.000
D03 Melanoma in situ	0.573	0.427	0.000
M08.2 Juvenile arthritis with systemic onset	0.572	0.428	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.570	0.430	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.570	0.430	0.000
M14.4 Arthropathy in amyloidosis	0.570	0.430	0.000
M14.3 Lipoid dermatoarthritis	0.570	0.430	0.000
M14.2 Diabetic arthropathy	0.570	0.430	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.570	0.430	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.570	0.430	0.000
C44 Other malignant neoplasms of skin	0.566	0.434	0.000
E07 Other disorders of thyroid	0.000	0.435	0.565
M06.48 Inflammatory polyarthropathy (Other)	0.560	0.440	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.560	0.440	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.560	0.440	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.560	0.440	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.560	0.440	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.560	0.440	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.560	0.440	0.000
C43 Malignant melanoma of skin	0.558	0.442	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.557	0.443	0.000
M11.9 Crystal arthropathy, unspecified	0.555	0.444	0.000
M08.9 Juvenile arthritis, unspecified	0.555	0.444	0.000
M08.8 Other juvenile arthritis	0.555	0.444	0.000
M08.4 Pauciarticular juvenile arthritis	0.555	0.444	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.555	0.444	0.000
M08.1 Juvenile ankylosing spondylitis	0.555	0.444	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.446	0.554
D04.3 Skin of other and unspecified parts of face	0.554	0.446	0.000
M05.18 Rheumatoid lung disease (Other)	0.553	0.447	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.553	0.447	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.553	0.447	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.553	0.447	0.000
M05.14 Rheumatoid lung disease (Hand)	0.553	0.447	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.553	0.447	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.553	0.447	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.553	0.447	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.553	0.447	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.552	0.448	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.450	0.550
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.450	0.550
K90.1 Tropical sprue	0.000	0.450	0.550
E06 Thyroiditis	0.000	0.451	0.549
M05.29 Rheumatoid vasculitis (Site unspecified)	0.547	0.453	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.546	0.454	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.543	0.457	0.000
M05.28 Rheumatoid vasculitis (Other)	0.532	0.468	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.532	0.468	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.532	0.468	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.532	0.468	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.532	0.468	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.532	0.468	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.532	0.468	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.532	0.468	0.000
C44.5 Skin of trunk	0.529	0.471	0.000
D04.9 Skin, unspecified	0.528	0.472	0.000
M13.8 Other specified arthritis	0.525	0.475	0.000
M13.1 Monoarthritis, not elsewhere classified	0.523	0.477	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.520	0.479	0.000
D03.5 Melanoma in situ of trunk	0.518	0.482	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.491	0.509
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.491	0.509
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.491	0.509
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.491	0.509
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.491	0.509
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.491	0.509
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.491	0.509
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.491	0.509
M12.3 Palindromic rheumatism	0.508	0.492	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.492	0.508
E61.8 Deficiency of other specified nutrient elements	0.000	0.492	0.508
E61.7 Deficiency of multiple nutrient elements	0.000	0.492	0.508
E61.6 Vanadium deficiency	0.000	0.492	0.508
E61.5 Molybdenum deficiency	0.000	0.492	0.508
E61.4 Chromium deficiency	0.000	0.492	0.508
E61.3 Manganese deficiency	0.000	0.492	0.508
E61.0 Copper deficiency	0.000	0.492	0.508
D07.1 Vulva	0.507	0.493	0.000
E14.4 With neurological complications	0.000	0.493	0.506
K90.8 Other intestinal malabsorption	0.000	0.495	0.505
C43.6 Malignant melanoma of upper limb, including shoulder	0.504	0.496	0.000
M11.1 Familial chondrocalcinosis	0.502	0.498	0.000
M11.0 Hydroxyapatite deposition disease	0.502	0.498	0.000
D04.7 Skin of lower limb, including hip	0.499	0.501	0.000
M12.5 Traumatic arthropathy	0.498	0.502	0.000
M12.4 Intermittent hydrarthrosis	0.498	0.502	0.000
M12.1 Kaschin-Beck disease	0.498	0.502	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.498	0.502	0.000
E51.2 Wernicke's encephalopathy	0.000	0.502	0.498
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.496	0.504	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.496	0.504	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.496	0.504	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.496	0.504	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.496	0.504	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.496	0.504	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.496	0.504	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.496	0.504	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.496	0.504	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.496	0.504	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.496	0.504	0.000
M07.18 Arthritis mutilans (Other)	0.496	0.504	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.496	0.504	0.000
M07.16 Arthritis mutilans (Lower leg)	0.496	0.504	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.496	0.504	0.000
M07.14 Arthritis mutilans (Hand)	0.496	0.504	0.000
M07.13 Arthritis mutilans (Forearm)	0.496	0.504	0.000
M07.12 Arthritis mutilans (Upper arm)	0.496	0.504	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.496	0.504	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.496	0.504	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.496	0.504	0.000
M07.28 Psoriatic spondylitis (Other)	0.496	0.504	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.496	0.504	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.496	0.504	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.496	0.504	0.000
M07.24 Psoriatic spondylitis (Hand)	0.496	0.504	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.496	0.504	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.496	0.504	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.496	0.504	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.496	0.504	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.496	0.504	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.496	0.504	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.496	0.504	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.496	0.504	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.496	0.504	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.496	0.504	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.496	0.504	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.496	0.504	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.496	0.504	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.496	0.504	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.496	0.504	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.496	0.504	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.496	0.504	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.496	0.504	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.496	0.504	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.496	0.504	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.496	0.504	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.496	0.504	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.496	0.504	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.496	0.504	0.000
D03.4 Melanoma in situ of scalp and neck	0.496	0.504	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.494	0.506	0.000
D04.4 Skin of scalp and neck	0.493	0.507	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.510	0.490
G36.8 Other specified acute disseminated demyelination	0.000	0.510	0.490
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.510	0.490
D03.6 Melanoma in situ of upper limb, including shoulder	0.486	0.514	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.517	0.483
E51.8 Other manifestations of thiamine deficiency	0.000	0.517	0.483
E51.1 Beriberi	0.000	0.517	0.483
C44.3 Skin of other and unspecified parts of face	0.483	0.517	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.518	0.482
M06.88 Other specified rheumatoid arthritis (Other)	0.481	0.519	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.481	0.519	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.481	0.519	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.481	0.519	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.481	0.519	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.481	0.519	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.481	0.519	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.481	0.519	0.000
M11.8 Other specified crystal arthropathies	0.480	0.519	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.480	0.519	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.519	0.480
E44.0 Moderate protein-energy malnutrition	0.000	0.519	0.480
D06.1 Exocervix	0.481	0.519	0.000
C43.4 Malignant melanoma of scalp and neck	0.476	0.524	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.474	0.526	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.528	0.472
E50.8 Other manifestations of vitamin A deficiency	0.000	0.528	0.472
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.528	0.472
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.528	0.472
E50.5 Vitamin A deficiency with night blindness	0.000	0.528	0.472
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.528	0.472
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.528	0.472
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.528	0.472
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.528	0.472
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.528	0.472
E63.9 Nutritional deficiency, unspecified	0.000	0.528	0.472
E63.8 Other specified nutritional deficiencies	0.000	0.528	0.472
E63.1 Imbalance of constituents of food intake	0.000	0.528	0.472
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.528	0.472
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.528	0.472
E64.8 Sequelae of other nutritional deficiencies	0.000	0.528	0.472
E64.3 Sequelae of rickets	0.000	0.528	0.472
E64.2 Sequelae of vitamin C deficiency	0.000	0.528	0.472
E64.1 Sequelae of vitamin A deficiency	0.000	0.528	0.472
E64.0 Sequelae of protein-energy malnutrition	0.000	0.528	0.472
M13.80 Other specified arthritis (Multiple sites)	0.469	0.530	0.000
M12.2 Villonodular synovitis (pigmented)	0.466	0.533	0.000
M07.68 Other enteropathic arthropathies (Other)	0.466	0.533	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.466	0.533	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.466	0.533	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.466	0.533	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.466	0.533	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.466	0.533	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.466	0.533	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.466	0.533	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.466	0.533	0.000
M10 Gout	0.463	0.537	0.000
D09 Carcinoma in situ of other and unspecified sites	0.463	0.537	0.000
D02.0 Larynx	0.462	0.538	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.462	0.538	0.000
E13.8 With unspecified complications	0.000	0.543	0.457
E13.7 With multiple complications	0.000	0.543	0.457
E13.6 With other specified complications	0.000	0.543	0.457
E13.5 With peripheral circulatory complications	0.000	0.543	0.457
E13.4 With neurological complications	0.000	0.543	0.457
E13.2 With renal complications	0.000	0.543	0.457
E13.1 With ketoacidosis	0.000	0.543	0.457
E13.0 With coma	0.000	0.543	0.457
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.455	0.544	0.000
D07.2 Vagina	0.454	0.546	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.547	0.453
E56.8 Deficiency of other vitamins	0.000	0.547	0.453
E56.0 Deficiency of vitamin E	0.000	0.547	0.453
D07.4 Penis	0.452	0.548	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.452	0.548	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.548	0.452
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.451	0.549	0.000
E61.1 Iron deficiency	0.000	0.551	0.449
D86 Sarcoidosis	0.000	0.555	0.445
E13.3 With ophthalmic complications	0.000	0.562	0.438
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.436	0.564	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.435	0.565	0.000
M11.2 Other chondrocalcinosis	0.434	0.566	0.000
E53.1 Pyridoxine deficiency	0.000	0.567	0.433
E53.0 Riboflavin deficiency	0.000	0.567	0.433
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.430	0.570	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.430	0.570	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.430	0.570	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.430	0.570	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.430	0.570	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.430	0.570	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.430	0.570	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.430	0.570	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.430	0.570	0.000
D03.8 Melanoma in situ of other sites	0.428	0.572	0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.427	0.572	0.000
E56.1 Deficiency of vitamin K	0.000	0.574	0.426
M07.69 Other enteropathic arthropathies (Site unspecified)	0.425	0.575	0.000
D04.5 Skin of trunk	0.425	0.575	0.000
C44.4 Skin of scalp and neck	0.425	0.575	0.000
D06.7 Other parts of cervix	0.424	0.576	0.000
D04.8 Skin of other sites	0.424	0.576	0.000
D04.0 Skin of lip	0.424	0.576	0.000
L40-L45 Papulosquamous disorders	0.423	0.577	0.000
D86.0 Sarcoidosis of lung	0.000	0.583	0.417
D06.0 Endocervix	0.416	0.584	0.000
D03.9 Melanoma in situ, unspecified	0.411	0.589	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations