TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs6935921
log Bayes Factor = 47.243
Chromosome 6   position 161,108,536  (GRCh37) Explore rs6935921 on Ensembl!
Variant rs6935921 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Showing all nodes without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.001 0.999
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.001 0.999
I73 Other peripheral vascular diseases
0.000 0.002 0.998
I21 Acute myocardial infarction
0.000 0.002 0.998
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.003 0.997
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
I24 Other acute ischaemic heart diseases
0.000 0.007 0.993
E78.5 Hyperlipidaemia, unspecified
0.000 0.009 0.991
I77 Other disorders of arteries and arterioles
0.000 0.012 0.988
I77.1 Stricture of artery
0.000 0.019 0.981
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.021 0.979
I22 Subsequent myocardial infarction
0.000 0.026 0.974
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.040 0.960
I21.9 Acute myocardial infarction, unspecified
0.000 0.044 0.956
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.046 0.954
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.072 0.928
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.076 0.924
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.085 0.915
I60-I69 Cerebrovascular diseases
0.000 0.086 0.914
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.088 0.912
I77.8 Other specified disorders of arteries and arterioles
0.000 0.094 0.906
I24.8 Other forms of acute ischaemic heart disease
0.000 0.100 0.900
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.122 0.878
I74 Arterial embolism and thrombosis
0.000 0.130 0.870
I60 Subarachnoid haemorrhage
0.000 0.133 0.867
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.138 0.862
Z95.3 Presence of xenogenic heart valve
0.000 0.140 0.860
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.144 0.856
I25.4 Coronary artery aneurysm
0.000 0.158 0.842
I25.5 Ischaemic cardiomyopathy
0.000 0.160 0.840
I70 Atherosclerosis
0.000 0.162 0.838
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.174 0.826
E78.1 Pure hyperglyceridaemia
0.000 0.179 0.821
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.184 0.816
I62 Other nontraumatic intracranial haemorrhage
0.000 0.194 0.806
I25.3 Aneurysm of heart
0.000 0.206 0.794
I61 Intracerebral haemorrhage
0.000 0.230 0.770
E78.8 Other disorders of lipoprotein metabolism
0.000 0.232 0.768
E78.2 Mixed hyperlipidaemia
0.000 0.244 0.756
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.247 0.753
I77.0 Arteriovenous fistula, acquired
0.000 0.251 0.749
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.252 0.748
E78.6 Lipoprotein deficiency
0.000 0.259 0.741
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.260 0.740
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.260 0.740
I77.2 Rupture of artery
0.000 0.266 0.734
I35 Nonrheumatic aortic valve disorders
0.000 0.280 0.720
I35.0 Aortic (valve) stenosis
0.000 0.280 0.720
I24.1 Dressler's syndrome
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.284 0.716
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.715
I00-I02 Acute rheumatic fever
0.000 0.285 0.715
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
I27 Other pulmonary heart diseases
0.000 0.289 0.711
I74.5 Embolism and thrombosis of iliac artery
0.000 0.289 0.711
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.291 0.709
I77.5 Necrosis of artery
0.000 0.292 0.708
I77.4 Coeliac artery compression syndrome
0.000 0.292 0.708
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.294 0.706
I30-I52 Other forms of heart disease
0.000 0.297 0.703
I70.0 Atherosclerosis of aorta
0.000 0.300 0.699
I70.1 Atherosclerosis of renal artery
0.000 0.301 0.699
E78.4 Other hyperlipidaemia
0.000 0.304 0.696
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.308 0.692
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.309 0.691
I22.8 Subsequent myocardial infarction of other sites
0.000 0.310 0.690
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.313 0.687
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.316 0.684
I72 Other aneurysm
0.000 0.317 0.683
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.319 0.681
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.326 0.674
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.327 0.672
I50 Heart failure
0.000 0.328 0.672
I27.2 Other secondary pulmonary hypertension
0.000 0.330 0.670
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.331 0.669
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.336 0.664
I23 Certain current complications following acute myocardial infarction
0.000 0.341 0.659
I71 Aortic aneurysm and dissection
0.000 0.348 0.652
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.348 0.652
I77.3 Arterial fibromuscular dysplasia
0.000 0.348 0.651
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.350 0.650
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.359 0.641
I21.4 Acute subendocardial myocardial infarction
0.000 0.362 0.638
I50.9 Heart failure, unspecified
0.000 0.368 0.632
I50.1 Left ventricular failure
0.000 0.373 0.627
I73.8 Other specified peripheral vascular diseases
0.000 0.374 0.626
I45 Other conduction disorders
0.000 0.376 0.624
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.378 0.622
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.378 0.622
I28 Other diseases of pulmonary vessels
0.000 0.378 0.622
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.379 0.621
I35.8 Other aortic valve disorders
0.000 0.387 0.613
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.393 0.607
I70.9 Generalised and unspecified atherosclerosis
0.000 0.399 0.601
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.400 0.600
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.401 0.598
I31 Other diseases of pericardium
0.000 0.403 0.597
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.406 0.594
I72.4 Aneurysm of artery of lower extremity
0.000 0.410 0.590
I45.9 Conduction disorder, unspecified
0.000 0.418 0.582
I05-I09 Chronic rheumatic heart diseases
0.000 0.418 0.582
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.421 0.579
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.430 0.570
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.438 0.562
I62.1 Nontraumatic extradural haemorrhage
0.000 0.438 0.562
I20.8 Other forms of angina pectoris
0.000 0.440 0.560
I31.9 Disease of pericardium, unspecified
0.000 0.441 0.559
I70.8 Atherosclerosis of other arteries
0.000 0.441 0.558
I60.8 Other subarachnoid haemorrhage
0.000 0.444 0.556
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.445 0.555
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.445 0.555
I30 Acute pericarditis
0.000 0.448 0.552
I27.0 Primary pulmonary hypertension
0.000 0.457 0.543
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.459 0.540
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.466 0.533
I45.8 Other specified conduction disorders
0.000 0.470 0.530
I72.8 Aneurysm of other specified arteries
0.000 0.472 0.528
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.474 0.526
I45.6 Preexcitation syndrome
0.000 0.475 0.525
I72.3 Aneurysm of iliac artery
0.000 0.475 0.525
I68.0 Cerebral amyloid angiopathy
0.000 0.475 0.525
I74.8 Embolism and thrombosis of other arteries
0.000 0.477 0.523
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.477 0.523
Z92.2 Personal history of long-term (current) use of other medicaments
0.000 0.485 0.515
I02 Rheumatic chorea
0.000 0.487 0.512
I01 Rheumatic fever with heart involvement
0.000 0.487 0.512
I00 Rheumatic fever without mention of heart involvement
0.000 0.487 0.512
I27.1 Kyphoscoliotic heart disease
0.000 0.490 0.510
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.494 0.506
I35.1 Aortic (valve) insufficiency
0.000 0.495 0.505
I52 Other heart disorders in diseases classified elsewhere
0.000 0.496 0.504
I48 Atrial fibrillation and flutter
0.000 0.496 0.504
I41 Myocarditis in diseases classified elsewhere
0.000 0.496 0.504
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.496 0.504
I32 Pericarditis in diseases classified elsewhere
0.000 0.496 0.504
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.498 0.501
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.499 0.501
Z95.4 Presence of other heart-valve replacement
0.000 0.499 0.501
I36 Nonrheumatic tricuspid valve disorders
0.000 0.500 0.500
I65.2 Occlusion and stenosis of carotid artery
0.000 0.501 0.499
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.501 0.498
I61.8 Other intracerebral haemorrhage
0.000 0.504 0.496
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.507 0.493
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.507 0.493
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.507 0.493
I40 Acute myocarditis
0.000 0.507 0.492
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.510 0.490
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.510 0.490
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.515 0.485
I28.8 Other specified diseases of pulmonary vessels
0.000 0.517 0.482
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.522 0.478
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.523 0.476
I79.1 Aortitis in diseases classified elsewhere
0.000 0.523 0.476
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.523 0.476
I26 Pulmonary embolism
0.000 0.524 0.476
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.526 0.474
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.527 0.472
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.527 0.472
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.527 0.472
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.527 0.472
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.527 0.472
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.527 0.472
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.527 0.472
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.532 0.468
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.532 0.468
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.532 0.468
I78 Diseases of capillaries
0.000 0.537 0.463
I07 Rheumatic tricuspid valve diseases
0.000 0.538 0.462
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.538 0.462
I30.1 Infective pericarditis
0.000 0.545 0.455
I45.0 Right fascicular block
0.000 0.552 0.448
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.554 0.446
I28.1 Aneurysm of pulmonary artery
0.000 0.554 0.446
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.554 0.446
I72.2 Aneurysm of renal artery
0.000 0.554 0.446
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.554 0.446
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.554 0.446
I65.1 Occlusion and stenosis of basilar artery
0.000 0.554 0.446
I45.2 Bifascicular block
0.000 0.556 0.444
I72.1 Aneurysm of artery of upper extremity
0.000 0.556 0.444
I27.9 Pulmonary heart disease, unspecified
0.000 0.559 0.441
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.563 0.437
I45.4 Nonspecific intraventricular block
0.000 0.563 0.437
I71.0 Dissection of aorta [any part]
0.000 0.569 0.431
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.569 0.431
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.569 0.431
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.570 0.430
I31.8 Other specified diseases of pericardium
0.000 0.572 0.428
I31.2 Haemopericardium, not elsewhere classified
0.000 0.572 0.428
I31.1 Chronic constrictive pericarditis
0.000 0.573 0.427
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.574 0.426
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.575 0.425
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.575 0.425
I72.9 Aneurysm of unspecified site
0.000 0.580 0.420
I31.0 Chronic adhesive pericarditis
0.000 0.584 0.416
I23.8 Other current complications following acute myocardial infarction
0.000 0.585 0.414
I08 Multiple valve diseases
0.000 0.585 0.415
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.594 0.406
I08.0 Disorders of both mitral and aortic valves
0.000 0.597 0.403
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.599 0.400
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.601 0.399
I38 Endocarditis, valve unspecified
0.000 0.602 0.398
I45.3 Trifascicular block
0.000 0.602 0.397
I30.8 Other forms of acute pericarditis
0.000 0.604 0.396
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.604 0.396
I27.8 Other specified pulmonary heart diseases
0.000 0.607 0.393
I06 Rheumatic aortic valve diseases
0.000 0.612 0.388
I67 Other cerebrovascular diseases
0.000 0.618 0.382
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.620 0.380
I35.9 Aortic valve disorder, unspecified
0.000 0.622 0.378
I07.1 Tricuspid insufficiency
0.000 0.623 0.377
I30.9 Acute pericarditis, unspecified
0.000 0.624 0.376
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.627 0.373
I05 Rheumatic mitral valve diseases
0.000 0.630 0.369
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.632 0.367
I01.8 Other acute rheumatic heart disease
0.000 0.632 0.367
I01.2 Acute rheumatic myocarditis
0.000 0.632 0.367
I01.1 Acute rheumatic endocarditis
0.000 0.632 0.367
I01.0 Acute rheumatic pericarditis
0.000 0.632 0.367
I02.9 Rheumatic chorea without heart involvement
0.000 0.632 0.367
I02.0 Rheumatic chorea with heart involvement
0.000 0.632 0.367
I37 Pulmonary valve disorders
0.000 0.637 0.363
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.638 0.362
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.638 0.362
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.638 0.362
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.638 0.362
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.638 0.362
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.638 0.362
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.638 0.362
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.638 0.362
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.638 0.362
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.638 0.362
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.638 0.362
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.638 0.362
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.638 0.362
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.638 0.362
I48.4 Atypical atrial flutter
0.000 0.638 0.362
I48.3 Typical atrial flutter
0.000 0.638 0.362
I48.2 Chronic atrial fibrillation
0.000 0.638 0.362
I48.1 Persistent atrial fibrillation
0.000 0.638 0.362
I48.0 Paroxysmal atrial fibrillation
0.000 0.638 0.362
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.638 0.362
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.638 0.362
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.638 0.362
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.641 0.358
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.641 0.358
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.641 0.358
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.641 0.358
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.642 0.358
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.645 0.355
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.646 0.354
I40.9 Acute myocarditis, unspecified
0.000 0.647 0.353
I40.8 Other acute myocarditis
0.000 0.647 0.353
I40.1 Isolated myocarditis
0.000 0.647 0.353
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.648 0.351
I66.8 Occlusion and stenosis of other cerebral artery
0.001 0.652 0.347
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.001 0.652 0.347
I66.3 Occlusion and stenosis of cerebellar arteries
0.001 0.652 0.347
I66.2 Occlusion and stenosis of posterior cerebral artery
0.001 0.652 0.347
I66.1 Occlusion and stenosis of anterior cerebral artery
0.001 0.652 0.347
I63 Cerebral infarction
0.000 0.655 0.345
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.658 0.341
I40.0 Infective myocarditis
0.000 0.659 0.341
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.660 0.340
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.660 0.340
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.660 0.340
I08.9 Multiple valve disease, unspecified
0.000 0.662 0.338
Z82.2 Family history of deafness and hearing loss
0.000 0.662 0.338
I72.0 Aneurysm of carotid artery
0.000 0.663 0.337
I78.9 Disease of capillaries, unspecified
0.000 0.668 0.332
I07.9 Tricuspid valve disease, unspecified
0.000 0.668 0.331
I07.8 Other tricuspid valve diseases
0.000 0.668 0.331
I07.2 Tricuspid stenosis with insufficiency
0.000 0.668 0.331
I07.0 Tricuspid stenosis
0.000 0.668 0.331
I45.5 Other specified heart block
0.000 0.671 0.329
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.684 0.316
I09 Other rheumatic heart diseases
0.001 0.685 0.315
I66.0 Occlusion and stenosis of middle cerebral artery
0.001 0.688 0.311
I77.6 Arteritis, unspecified
0.000 0.689 0.311
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.690 0.310
I67.2 Cerebral atherosclerosis
0.000 0.692 0.308
I20.1 Angina pectoris with documented spasm
0.000 0.693 0.306
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.695 0.304
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.698 0.302
I33 Acute and subacute endocarditis
0.000 0.702 0.298
I67.9 Cerebrovascular disease, unspecified
0.000 0.705 0.295
Z82.1 Family history of blindness and visual loss
0.000 0.705 0.294
I08.8 Other multiple valve diseases
0.000 0.706 0.294
I10-I15 Hypertensive diseases
0.000 0.709 0.291
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.709 0.290
I31.3 Pericardial effusion (noninflammatory)
0.000 0.713 0.287
I45.1 Other and unspecified right bundle-branch block
0.000 0.716 0.284
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.721 0.278
I06.8 Other rheumatic aortic valve diseases
0.000 0.721 0.278
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.721 0.278
I78.8 Other diseases of capillaries
0.000 0.722 0.277
I06.1 Rheumatic aortic insufficiency
0.000 0.724 0.276
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.726 0.274
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.726 0.274
I67.5 Moyamoya disease
0.000 0.726 0.274
I67.4 Hypertensive encephalopathy
0.000 0.726 0.274
I67.3 Progressive vascular leukoencephalopathy
0.000 0.726 0.274
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.729 0.271
I63.9 Cerebral infarction, unspecified
0.000 0.731 0.269
I05.1 Rheumatic mitral insufficiency
0.000 0.734 0.266
I05.8 Other mitral valve diseases
0.000 0.735 0.265
I46 Cardiac arrest
0.000 0.735 0.265
I37.9 Pulmonary valve disorder, unspecified
0.000 0.739 0.260
I37.8 Other pulmonary valve disorders
0.000 0.739 0.260
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.739 0.260
I63.8 Other cerebral infarction
0.000 0.739 0.261
I71.3 Abdominal aortic aneurysm, ruptured
0.001 0.744 0.255
I05.2 Mitral stenosis with insufficiency
0.000 0.746 0.254
I06.0 Rheumatic aortic stenosis
0.000 0.747 0.253
I05.9 Mitral valve disease, unspecified
0.000 0.747 0.253
Z82.3 Family history of stroke
0.000 0.748 0.252
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.753 0.247
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.753 0.247
I05.0 Mitral stenosis
0.000 0.755 0.245
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.757 0.243
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.001 0.758 0.241
I37.0 Pulmonary valve stenosis
0.000 0.763 0.236
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.765 0.235
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.769 0.231
I11 Hypertensive heart disease
0.000 0.771 0.228
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.772 0.228
I09.8 Other specified rheumatic heart diseases
0.001 0.774 0.226
I09.2 Chronic rheumatic pericarditis
0.001 0.774 0.226
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.774 0.226
I09.0 Rheumatic myocarditis
0.001 0.774 0.226
Z95.2 Presence of prosthetic heart valve
0.000 0.774 0.226
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.778 0.222
I13 Hypertensive heart and renal disease
0.000 0.791 0.208
I50.0 Congestive heart failure
0.000 0.794 0.206
I67.8 Other specified cerebrovascular diseases
0.000 0.805 0.195
I46.1 Sudden cardiac death, so described
0.000 0.810 0.190
I51 Complications and ill-defined descriptions of heart disease
0.000 0.814 0.186
I33.9 Acute endocarditis, unspecified
0.001 0.816 0.183
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.821 0.179
I15 Secondary hypertension
0.000 0.827 0.173
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.830 0.170
I37.1 Pulmonary valve insufficiency
0.001 0.834 0.165
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.836 0.164
I73.0 Raynaud's syndrome
0.000 0.846 0.154
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.850 0.150
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.850 0.150
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.850 0.150
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.850 0.150
Z92 Personal history of medical treatment
0.000 0.852 0.148
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.000 0.853 0.147
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.857 0.143
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.863 0.137
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.863 0.137
I15.9 Seconday hypertension, unspecified
0.000 0.864 0.136
I51.9 Heart disease, unspecified
0.000 0.864 0.136
I51.5 Myocardial degeneration
0.000 0.865 0.135
I34 Nonrheumatic mitral valve disorders
0.000 0.866 0.134
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.867 0.133
I78.1 Naevus, nonneoplastic
0.000 0.867 0.133
Z83 Family history of other specific disorders
0.000 0.867 0.133
I51.6 Cardiovascular disease, unspecified
0.000 0.868 0.132
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.869 0.131
I09.9 Rheumatic heart disease, unspecified
0.001 0.875 0.124
I15.8 Other secondary hypertension
0.000 0.875 0.124
I15.2 Hypertension secondary to endocrine disorders
0.000 0.875 0.124
I51.0 Cardiac septal defect, acquired
0.000 0.876 0.124
I10 Essential (primary) hypertension
0.000 0.878 0.122
Z97 Presence of other devices
0.000 0.878 0.122
Z95.0 Presence of cardiac pacemaker
0.000 0.880 0.120
Z83.3 Family history of diabetes mellitus
0.000 0.882 0.118
Z83.6 Family history of diseases of the respiratory system
0.000 0.885 0.115
I46.0 Cardiac arrest with successful resuscitation
0.000 0.885 0.115
I15.0 Renovascular hypertension
0.000 0.886 0.113
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.888 0.112
Z84 Family history of other conditions
0.000 0.889 0.111
Z92.0 Personal history of contraception
0.000 0.889 0.111
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.890 0.110
Z97.4 Presence of external hearing-aid
0.000 0.891 0.109
I46.9 Cardiac arrest, unspecified
0.000 0.892 0.108
Z83.5 Family history of eye and ear disorders
0.000 0.892 0.108
I51.8 Other ill-defined heart diseases
0.000 0.893 0.107
Z92.9 Personal history of medical treatment, unspecified
0.000 0.893 0.106
Z92.5 Personal history of rehabilitation measures
0.000 0.893 0.106
Z89 Acquired absence of limb
0.000 0.894 0.106
Z97.1 Presence of artificial limb (complete)(partial)
0.000 0.895 0.105
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.895 0.105
I67.1 Cerebral aneurysm, nonruptured
0.000 0.897 0.103
I51.4 Myocarditis, unspecified
0.000 0.898 0.101
Z83.0 Family history of human immunodeficiency virus [HIV]
0.000 0.904 0.095
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.000 0.905 0.095
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.000 0.905 0.095
Z83.1 Family history of other infectious and parasitic diseases
0.000 0.907 0.093
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.909 0.091
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.910 0.090
Z81 Family history of mental and behavioural disorders
0.000 0.911 0.089
Z99.2 Dependence on renal dialysis
0.000 0.913 0.087
I33.0 Acute and subacute infective endocarditis
0.001 0.915 0.084
Z84.2 Family history of other diseases of the genito-urinary system
0.000 0.915 0.085
Z89.9 Acquired absence of limb, unspecified
0.000 0.916 0.084
I47 Paroxysmal tachycardia
0.000 0.916 0.084
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.000 0.916 0.083
Z97.3 Presence of spectacles and contact lenses
0.000 0.917 0.083
I15.1 Hypertension secondary to other renal disorders
0.000 0.917 0.082
Z89.4 Acquired absence of foot and ankle
0.000 0.917 0.082
Z84.8 Family history of other specified conditions
0.000 0.919 0.081
Z92.8 Personal history of other medical treatment
0.000 0.920 0.080
Z84.3 Family history of consanguinity
0.000 0.920 0.079
Z84.0 Family history of diseases of the skin and subcutaneous tissue
0.000 0.920 0.079
Z84.1 Family history of disorders of the kidney and ureter
0.000 0.922 0.078
Z89.3 Acquired absence of both upper limbs [any level]
0.000 0.924 0.076
Z89.1 Acquired absence of hand and wrist
0.000 0.924 0.076
Z89.8 Acquired absence of upper and lower limbs [any level]
0.000 0.924 0.076
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.925 0.075
Z97.0 Presence of artificial eye
0.000 0.925 0.075
Z89.2 Acquired absence of upper limb above wrist
0.000 0.927 0.073
Z97.8 Presence of other specified devices
0.000 0.929 0.071
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.929 0.071
Z89.5 Acquired absence of leg at or below knee
0.000 0.930 0.070
I44 Atrioventricular and left bundle-branch block
0.000 0.930 0.070
Z97.5 Presence of (intra-uterine) contraceptive device
0.000 0.930 0.069
I69 Sequelae of cerebrovascular disease
0.001 0.931 0.069
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.000 0.931 0.069
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.931 0.069
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.931 0.069
Z89.6 Acquired absence of leg above knee
0.000 0.933 0.067
Z99.4 Dependence on artificial heart
0.000 0.935 0.065
Z81.4 Family history of other substance abuse
0.000 0.936 0.064
Z81.3 Family history of other psychoactive substance abuse
0.000 0.936 0.064
Z81.2 Family history of tobacco abuse
0.000 0.936 0.064
Z81.1 Family history of alcohol abuse
0.000 0.936 0.064
Z81.0 Family history of mental retardation
0.000 0.936 0.064
I12 Hypertensive renal disease
0.000 0.938 0.062
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.940 0.060
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.940 0.059
Z99.8 Dependence on other enabling machines and devices
0.000 0.941 0.059
Z99.0 Dependence on aspirator
0.000 0.943 0.056
I44.4 Left anterior fascicular block
0.000 0.945 0.055
I44.3 Other and unspecified atrioventricular block
0.000 0.947 0.052
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.948 0.052
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.948 0.051
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.949 0.051
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.949 0.051
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.949 0.051
I98.0 Cardiovascular syphilis
0.000 0.949 0.051
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.001 0.950 0.050
I44.5 Left posterior fascicular block
0.000 0.950 0.050
Z92.4 Personal history of major surgery, not elsewhere classified
0.000 0.950 0.050
I44.1 Atrioventricular block, second degree
0.000 0.952 0.048
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.000 0.952 0.048
Z81.8 Family history of other mental and behavioural disorders
0.000 0.952 0.048
Z99.1 Dependence on respirator
0.000 0.954 0.046
I99 Other and unspecified disorders of circulatory system
0.000 0.954 0.045
I42 Cardiomyopathy
0.000 0.954 0.046
Z98 Other postsurgical states
0.000 0.955 0.045
I47.0 Reentry ventricular arrhythmia
0.000 0.956 0.044
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.956 0.044
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.000 0.956 0.044
Z83.7 Family history of diseases of the digestive system
0.000 0.957 0.043
T82.0 Mechanical complication of heart valve prosthesis
0.000 0.957 0.043
H83.0 Labyrinthitis
0.000 0.958 0.042
Z98.2 Presence of cerebrospinal fluid drainage device
0.000 0.958 0.042
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.000 0.958 0.042
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.000 0.958 0.042
I34.1 Mitral (valve) prolapse
0.000 0.959 0.041
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.960 0.039
R01.1 Cardiac murmur, unspecified
0.000 0.960 0.040
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.000 0.961 0.039
T82.4 Mechanical complication of vascular dialysis catheter
0.000 0.961 0.039
T82.3 Mechanical complication of other vascular grafts
0.000 0.963 0.037
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.001 0.964 0.035
I42.8 Other cardiomyopathies
0.000 0.964 0.036
I44.0 Atrioventricular block, first degree
0.000 0.965 0.035
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.966 0.033
I42.5 Other restrictive cardiomyopathy
0.000 0.967 0.033
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.967 0.033
I44.6 Other and unspecified fascicular block
0.000 0.967 0.032
I47.2 Ventricular tachycardia
0.000 0.968 0.032
I42.4 Endocardial fibroelastosis
0.000 0.968 0.032
Z94 Transplanted organ and tissue status
0.000 0.970 0.030
I49 Other cardiac arrhythmias
0.000 0.970 0.030
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.970 0.030
T82.1 Mechanical complication of cardiac electronic device
0.000 0.970 0.030
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.971 0.028
I97.0 Postcardiotomy syndrome
0.001 0.971 0.028
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.973 0.027
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.975 0.025
I49.9 Cardiac arrhythmia, unspecified
0.000 0.975 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2025 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.