TreeWAS – Variant ID: rs71325459

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.000	0.000	1.000
Chapter II Neoplasms	0.000	0.000	1.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.000	1.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.000	1.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.000	0.000	1.000
Chapter XXI Factors influencing health status and contact with health services	0.000	0.000	1.000
Z85 Personal history of malignant neoplasm	0.000	0.000	1.000
# Top node	0.000	0.000	1.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.001	0.999
C61 Malignant neoplasm of prostate	0.000	0.001	0.999
C79 Secondary malignant neoplasm of other sites	0.000	0.002	0.998
Z92 Personal history of medical treatment	0.000	0.002	0.998
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.004	0.996
R33 Retention of urine	0.000	0.005	0.995
Z40-Z54 Persons encountering health services for specific procedures and health care	0.000	0.006	0.994
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.006	0.994
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.006	0.994
R31 Unspecified haematuria	0.000	0.011	0.989
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.011	0.989
Z92.3 Personal history of irradiation	0.000	0.012	0.988
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.015	0.985
Chapter XIV Diseases of the genitourinary system	0.000	0.017	0.983
C50-C50 Malignant neoplasm of breast	0.000	0.018	0.982
Z51 Other medical care	0.000	0.018	0.982
Z50 Care involving use of rehabilitation procedures	0.000	0.023	0.977
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.025	0.975
D10-D36 Benign neoplasms	0.000	0.027	0.973
N30-N39 Other diseases of urinary system	0.000	0.027	0.973
D22 Melanocytic naevi	0.000	0.028	0.972
C50 Malignant neoplasm of breast	0.000	0.030	0.970
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.034	0.966
N32 Other disorders of bladder	0.000	0.034	0.966
C77.3 Axillary and upper limb lymph nodes	0.000	0.035	0.965
N32.8 Other specified disorders of bladder	0.000	0.039	0.961
Z80 Family history of malignant neoplasm	0.000	0.043	0.957
Z51.5 Palliative care	0.000	0.043	0.957
C50.9 Breast, unspecified	0.000	0.043	0.957
C44 Other malignant neoplasms of skin	0.000	0.046	0.954
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.048	0.952
D22.5 Melanocytic naevi of trunk	0.000	0.048	0.952
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.049	0.951
R50-R69 General symptoms and signs	0.000	0.050	0.950
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.057	0.943
D17 Benign lipomatous neoplasm	0.000	0.060	0.940
Z96 Presence of other functional implants	0.000	0.060	0.940
R21 Rash and other nonspecific skin eruption	0.000	0.061	0.939
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.064	0.936
Z51.1 Chemotherapy session for neoplasm	0.000	0.066	0.934
R39 Other symptoms and signs involving the urinary system	0.000	0.072	0.928
R53 Malaise and fatigue	0.000	0.073	0.927
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.080	0.920
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.082	0.918
Z50.1 Other physical therapy	0.000	0.085	0.915
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.086	0.914
N10-N16 Renal tubulo-interstitial diseases	0.000	0.087	0.913
R30 Pain associated with micturition	0.000	0.090	0.910
C77.5 Intrapelvic lymph nodes	0.000	0.100	0.900
R32 Unspecified urinary incontinence	0.000	0.103	0.897
C44.3 Skin of other and unspecified parts of face	0.000	0.108	0.892
Z96.0 Presence of urogenital implants	0.000	0.109	0.890
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.111	0.889
R50 Fever of unknown origin	0.000	0.111	0.889
Chapter VI Diseases of the nervous system	0.000	0.112	0.888
C43 Malignant melanoma of skin	0.000	0.112	0.888
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.123	0.877
C64-C68 Malignant neoplasms of urinary tract	0.000	0.124	0.876
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.125	0.875
N60-N64 Disorders of breast	0.000	0.126	0.874
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.128	0.872
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.129	0.871
Z42 Follow-up care involving plastic surgery	0.000	0.139	0.861
D00-D09 In situ neoplasms	0.000	0.141	0.859
R39.1 Other difficulties with micturition	0.000	0.142	0.858
Z94 Transplanted organ and tissue status	0.000	0.145	0.855
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.146	0.854
Z98 Other postsurgical states	0.000	0.146	0.854
Z99.2 Dependence on renal dialysis	0.000	0.153	0.847
C78.0 Secondary malignant neoplasm of lung	0.000	0.154	0.846
G90-G99 Other disorders of the nervous system	0.000	0.155	0.845
R30.0 Dysuria	0.000	0.155	0.845
R35 Polyuria	0.000	0.158	0.842
Z88.5 Personal history of allergy to narcotic agent	0.000	0.160	0.840
C77.2 Intra-abdominal lymph nodes	0.000	0.161	0.839
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.162	0.838
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.164	0.836
C44.1 Skin of eyelid, including canthus	0.000	0.164	0.836
N20-N23 Urolithiasis	0.000	0.165	0.835
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.165	0.835
Z86 Personal history of certain other diseases	0.000	0.166	0.834
Z85.6 Personal history of leukaemia	0.000	0.167	0.833
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.167	0.833
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.168	0.831
C78.2 Secondary malignant neoplasm of pleura	0.000	0.169	0.831
Z80.3 Family history of malignant neoplasm of breast	0.000	0.171	0.829
Z40 Prophylactic surgery	0.000	0.177	0.823
C77.1 Intrathoracic lymph nodes	0.000	0.179	0.821
Z96.6 Presence of orthopaedic joint implants	0.000	0.179	0.821
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.181	0.819
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.181	0.819
Z87 Personal history of other diseases and conditions	0.000	0.182	0.818
C50.1 Central portion of breast	0.000	0.182	0.818
Z50.5 Speech therapy	0.000	0.189	0.811
C44.5 Skin of trunk	0.000	0.190	0.810
N35 Urethral stricture	0.000	0.191	0.809
G81 Hemiplegia	0.000	0.197	0.803
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.198	0.802
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.200	0.800
C77.0 Lymph nodes of head, face and neck	0.000	0.204	0.796
C50.3 Lower-inner quadrant of breast	0.000	0.206	0.794
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.207	0.793
N23 Unspecified renal colic	0.000	0.208	0.792
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.209	0.791
Chapter XXII Codes for special purposes	0.000	0.211	0.789
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.212	0.788
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.213	0.787
D60-D64 Aplastic and other anaemias	0.000	0.216	0.784
R50.9 Fever, unspecified	0.000	0.217	0.783
G81.9 Hemiplegia, unspecified	0.000	0.222	0.778
R50.0 Fever with chills	0.000	0.223	0.777
R68 Other general symptoms and signs	0.000	0.224	0.776
N64 Other disorders of breast	0.000	0.226	0.774
R47-R49 Symptoms and signs involving speech and voice	0.000	0.227	0.773
N25-N29 Other disorders of kidney and ureter	0.000	0.228	0.772
N30 Cystitis	0.000	0.231	0.769
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.232	0.768
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.232	0.768
Z93 Artificial opening status	0.000	0.233	0.767
Z49 Care involving dialysis	0.000	0.233	0.767
Z86.0 Personal history of other neoplasms	0.000	0.233	0.767
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.234	0.766
C50.5 Lower-outer quadrant of breast	0.000	0.238	0.762
N13 Obstructive and reflux uropathy	0.000	0.240	0.760
R20 Disturbances of skin sensation	0.000	0.245	0.755
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.246	0.754
C80 Malignant neoplasm without specification of site	0.000	0.249	0.751
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.251	0.749
N32.3 Diverticulum of bladder	0.000	0.251	0.749
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.251	0.749
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.254	0.746
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.255	0.745
N36 Other disorders of urethra	0.000	0.255	0.745
Z94.0 Kidney transplant status	0.000	0.255	0.745
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.255	0.744
C67 Malignant neoplasm of bladder	0.000	0.256	0.744
K70-K77 Diseases of liver	0.738	0.262	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.000	0.264	0.736
Z99.3 Dependence on wheelchair	0.000	0.264	0.736
N60 Benign mammary dysplasia	0.000	0.265	0.735
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.265	0.735
C44.0 Skin of lip	0.000	0.266	0.734
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.268	0.732
D06 Carcinoma in situ of cervix uteri	0.000	0.271	0.729
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.273	0.727
N17-N19 Renal failure	0.000	0.274	0.726
Z92.0 Personal history of contraception	0.000	0.276	0.724
D34 Benign neoplasm of thyroid gland	0.000	0.276	0.724
N30.9 Cystitis, unspecified	0.000	0.276	0.724
K70 Alcoholic liver disease	0.724	0.276	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.278	0.722
Z97 Presence of other devices	0.000	0.278	0.722
K76 Other diseases of liver	0.721	0.279	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.280	0.720
Z98.0 Intestinal bypass and anastomosis status	0.000	0.281	0.719
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.283	0.717
Z84 Family history of other conditions	0.000	0.283	0.717
Z81 Family history of mental and behavioural disorders	0.000	0.283	0.717
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.283	0.717
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.283	0.717
R36 Urethral discharge	0.000	0.283	0.717
R95-R99 Ill-defined and unknown causes of mortality	0.000	0.283	0.717
Z85.0 Personal history of malignant neoplasm of digestive organs	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.283	0.717
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.283	0.716
C60 Malignant neoplasm of penis	0.000	0.283	0.716
C44.6 Skin of upper limb, including shoulder	0.000	0.284	0.716
C79.6 Secondary malignant neoplasm of ovary	0.000	0.284	0.715
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.284	0.715
C79.2 Secondary malignant neoplasm of skin	0.000	0.284	0.715
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.284	0.715
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.284	0.715
Z92.9 Personal history of medical treatment, unspecified	0.000	0.284	0.715
Z92.8 Personal history of other medical treatment	0.000	0.284	0.715
Z92.5 Personal history of rehabilitation measures	0.000	0.284	0.715
Z51.2 Other chemotherapy	0.000	0.285	0.715
Chapter XI Diseases of the digestive system	0.715	0.285	0.000
D27 Benign neoplasm of ovary	0.000	0.286	0.714
Z96.8 Presence of other specified functional implants	0.000	0.287	0.713
Z44 Fitting and adjustment of external prosthetic device	0.000	0.287	0.713
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.287	0.713
C77.8 Lymph nodes of multiple regions	0.000	0.287	0.713
C77.4 Inguinal and lower limb lymph nodes	0.000	0.287	0.713
Z88.6 Personal history of allergy to analgesic agent	0.000	0.287	0.713
Z51.0 Radiotherapy session	0.000	0.287	0.713
C73 Malignant neoplasm of thyroid gland	0.000	0.287	0.713
D11 Benign neoplasm of major salivary glands	0.000	0.289	0.711
Z41 Procedures for purposes other than remedying health state	0.000	0.290	0.710
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.710	0.290	0.000
Z96.7 Presence of other bone and tendon implants	0.000	0.291	0.709
D18 Haemangioma and lymphangioma, any site	0.000	0.292	0.708
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.292	0.708
Z50.2 Alcohol rehabilitation	0.000	0.293	0.707
N63 Unspecified lump in breast	0.000	0.294	0.706
Z51.9 Medical care, unspecified	0.000	0.296	0.704
Z51.6 Desensitisation to allergens	0.000	0.296	0.704
R56 Convulsions, not elsewhere classified	0.000	0.297	0.703
D26 Other benign neoplasms of uterus	0.000	0.299	0.701
G91 Hydrocephalus	0.000	0.299	0.701
Z50.6 Orthoptic training	0.000	0.299	0.701
Z50.3 Drug rehabilitation	0.000	0.299	0.701
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.299	0.701
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.299	0.700
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.300	0.700
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.302	0.698
N64.8 Other specified disorders of breast	0.000	0.302	0.698
D31 Benign neoplasm of eye and adnexa	0.000	0.302	0.698
D30 Benign neoplasm of urinary organs	0.000	0.302	0.698
D29 Benign neoplasm of male genital organs	0.000	0.302	0.698
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.000	0.302	0.698
D19 Benign neoplasm of mesothelial tissue	0.000	0.302	0.698
D16 Benign neoplasm of bone and articular cartilage	0.000	0.302	0.698
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.000	0.302	0.698
N37 Urethral disorders in diseases classified elsewhere	0.000	0.302	0.697
N34 Urethritis and urethral syndrome	0.000	0.302	0.697
N33 Bladder disorders in diseases classified elsewhere	0.000	0.302	0.697
D22.9 Melanocytic naevi, unspecified	0.000	0.303	0.697
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.303	0.697
D22.0 Melanocytic naevi of lip	0.000	0.303	0.697
K76.8 Other specified diseases of liver	0.696	0.304	0.000
C50.6 Axillary tail of breast	0.000	0.305	0.695
C50.0 Nipple and areola	0.000	0.305	0.695
D64 Other anaemias	0.000	0.305	0.695
N13.3 Other and unspecified hydronephrosis	0.000	0.305	0.695
D80-D89 Certain disorders involving the immune mechanism	0.000	0.305	0.694
N32.9 Bladder disorder, unspecified	0.000	0.306	0.694
R22.2 Localised swelling, mass and lump, trunk	0.000	0.307	0.693
N32.4 Rupture of bladder, nontraumatic	0.000	0.307	0.692
N32.2 Vesical fistula, not elsewhere classified	0.000	0.307	0.692
N32.1 Vesicointestinal fistula	0.000	0.307	0.692
K80 Cholelithiasis	0.692	0.308	0.000
N35.9 Urethral stricture, unspecified	0.000	0.308	0.692
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.309	0.691
R51 Headache	0.000	0.309	0.691
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.311	0.689
D23 Other benign neoplasms of skin	0.000	0.312	0.687
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.313	0.687
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.313	0.686
Z80.6 Family history of leukaemia	0.000	0.313	0.686
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.313	0.686
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.313	0.686
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.316	0.684
C44.8 Overlapping lesion of skin	0.000	0.316	0.684
Z86.6 Personal history of diseases of the nervous system and sense organs	0.000	0.316	0.684
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.317	0.683
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.317	0.683
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.318	0.682
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.318	0.682
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.318	0.682
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.318	0.682
D32 Benign neoplasm of meninges	0.000	0.318	0.682
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.000	0.318	0.681
R62 Lack of expected normal physiological development	0.000	0.318	0.681
R57 Shock, not elsewhere classified	0.000	0.318	0.681
R64 Cachexia	0.000	0.318	0.681
R58 Haemorrhage, not elsewhere classified	0.000	0.318	0.681
C50.4 Upper-outer quadrant of breast	0.000	0.319	0.681
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.320	0.680
C15-C26 Malignant neoplasms of digestive organs	0.000	0.321	0.679
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.321	0.679
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.677	0.323	0.000
D05 Carcinoma in situ of breast	0.000	0.323	0.677
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.325	0.675
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.326	0.674
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.000	0.326	0.674
C44.4 Skin of scalp and neck	0.000	0.326	0.674
Z96.9 Presence of functional implant, unspecified	0.000	0.326	0.674
Z96.5 Presence of tooth-root and mandibular implants	0.000	0.326	0.674
Z96.4 Presence of endocrine implants	0.000	0.326	0.674
Z96.3 Presence of artificial larynx	0.000	0.326	0.674
Z96.2 Presence of otological and audiological implants	0.000	0.326	0.674
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.327	0.673
R69 Unknown and unspecified causes of morbidity	0.000	0.327	0.673
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.329	0.671
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.331	0.669
K70.3 Alcoholic cirrhosis of liver	0.666	0.334	0.000
R39.2 Extrarenal uraemia	0.000	0.335	0.665
R39.0 Extravasation of urine	0.000	0.335	0.665
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.336	0.664
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.336	0.664
R60 Oedema, not elsewhere classified	0.000	0.337	0.663
D14 Benign neoplasm of middle ear and respiratory system	0.000	0.337	0.663
C67.9 Bladder, unspecified	0.000	0.337	0.663
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.338	0.662
R22.1 Localised swelling, mass and lump, neck	0.000	0.338	0.662
K04 Diseases of pulp and periapical tissues	0.659	0.341	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.341	0.658
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.341	0.658
Z99.8 Dependence on other enabling machines and devices	0.000	0.341	0.658
Z99.4 Dependence on artificial heart	0.000	0.341	0.658
Z99.0 Dependence on aspirator	0.000	0.341	0.658
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.344	0.656
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.345	0.655
R50.8 Other specified fever	0.000	0.345	0.655
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.345	0.655
N15 Other renal tubulo-interstitial diseases	0.000	0.345	0.655
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.345	0.655
N11 Chronic tubulo-interstitial nephritis	0.000	0.345	0.655
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.345	0.654
Z43 Attention to artificial openings	0.000	0.346	0.654
Z98.8 Other specified postsurgical states	0.000	0.346	0.654
Z52 Donors of organs and tissues	0.000	0.346	0.654
D09 Carcinoma in situ of other and unspecified sites	0.000	0.347	0.653
K76.6 Portal hypertension	0.652	0.348	0.000
R30.9 Painful micturition, unspecified	0.000	0.348	0.652
R30.1 Vesical tenesmus	0.000	0.348	0.652
R34 Anuria and oliguria	0.000	0.348	0.651
K80.1 Calculus of gallbladder with other cholecystitis	0.651	0.349	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.349	0.651
R47 Speech disturbances, not elsewhere classified	0.000	0.349	0.651
R22.0 Localised swelling, mass and lump, head	0.000	0.349	0.651
D03 Melanoma in situ	0.000	0.349	0.650
Z54 Convalescence	0.000	0.350	0.650
R68.8 Other specified general symptoms and signs	0.000	0.350	0.650
D10 Benign neoplasm of mouth and pharynx	0.000	0.352	0.648
C51-C58 Malignant neoplasms of female genital organs	0.000	0.352	0.648
D70 Agranulocytosis	0.000	0.354	0.646
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.354	0.646
G95 Other diseases of spinal cord	0.000	0.354	0.646
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.354	0.646
K04.7 Periapical abscess without sinus	0.644	0.356	0.000
G70-G73 Diseases of myoneural junction and muscle	0.000	0.357	0.643
K74 Fibrosis and cirrhosis of liver	0.643	0.357	0.000
C62 Malignant neoplasm of testis	0.000	0.358	0.642
K70.9 Alcoholic liver disease, unspecified	0.642	0.358	0.000
N18 Chronic renal failure	0.000	0.360	0.640
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.361	0.639
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.362	0.638
R50.2 Drug-induced fever	0.000	0.362	0.637
R50.1 Persistent fever	0.000	0.362	0.637
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.363	0.637
C43.9 Malignant melanoma of skin, unspecified	0.000	0.363	0.637
C43.8 Overlapping malignant melanoma of skin	0.000	0.363	0.637
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.363	0.637
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.363	0.637
C43.0 Malignant melanoma of lip	0.000	0.363	0.637
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.364	0.636
D06.9 Cervix, unspecified	0.000	0.364	0.636
Z93.3 Colostomy status	0.000	0.365	0.635
N10 Acute tubulo-interstitial nephritis	0.000	0.365	0.635
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.366	0.634
Z89 Acquired absence of limb	0.000	0.367	0.633
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.367	0.633
C71 Malignant neoplasm of brain	0.000	0.367	0.633
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.367	0.632
Z53 Persons encountering health services for specifie procedures, not carried out	0.000	0.368	0.632
D64.9 Anaemia, unspecified	0.000	0.369	0.631
D28 Benign neoplasm of other and unspecified female genital organs	0.000	0.370	0.630
K83 Other diseases of biliary tract	0.630	0.370	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.629	0.371	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.371	0.629
G93 Other disorders of brain	0.000	0.371	0.629
Z98.1 Arthrodesis status	0.000	0.372	0.628
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.372	0.628
C66 Malignant neoplasm of ureter	0.000	0.372	0.628
D55-D59 Haemolytic anaemias	0.000	0.372	0.627
K70.1 Alcoholic hepatitis	0.625	0.375	0.000
R61 Hyperhidrosis	0.000	0.377	0.623
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.377	0.623
N60.4 Mammary duct ectasia	0.000	0.379	0.621
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.379	0.621
R59 Enlarged lymph nodes	0.000	0.379	0.621
D72 Other disorders of white blood cells	0.000	0.380	0.620
C43.5 Malignant melanoma of trunk	0.000	0.381	0.618
G83 Other paralytic syndromes	0.000	0.383	0.617
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.383	0.617
Z46 Fitting and adjustment of other devices	0.000	0.383	0.617
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.383	0.617
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.383	0.617
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.383	0.617
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.383	0.617
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.383	0.617
Z99.1 Dependence on respirator	0.000	0.384	0.616
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.384	0.616
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.384	0.616
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.384	0.616
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.385	0.615
E10-E14 Diabetes mellitus	0.000	0.385	0.615
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.387	0.613
Z94.7 Corneal transplant status	0.000	0.387	0.613
Z94.6 Bone transplant status	0.000	0.387	0.613
Z94.5 Skin transplant status	0.000	0.387	0.613
Z94.3 Heart and lungs transplant status	0.000	0.387	0.613
Z94.2 Lung transplant status	0.000	0.387	0.613
Z94.1 Heart transplant status	0.000	0.387	0.613
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.387	0.612
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.388	0.612
Z87.8 Personal history of other specified conditions	0.000	0.389	0.611
N32.0 Bladder-neck obstruction	0.000	0.389	0.611
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.390	0.610
Z87.0 Personal history of diseases of the respiratory system	0.000	0.394	0.606
G96 Other disorders of central nervous system	0.000	0.394	0.606
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.394	0.606
G90 Disorders of autonomic nervous system	0.000	0.394	0.606
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.394	0.606
G92 Toxic encephalopathy	0.000	0.394	0.606
K82 Other diseases of gallbladder	0.606	0.394	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.394	0.606
Z49.1 Extracorporeal dialysis	0.000	0.395	0.604
K72 Hepatic failure, not elsewhere classified	0.602	0.398	0.000
Z53.8 Procedure not carried out for other reasons	0.000	0.398	0.602
Z50.8 Care involving use of rehabilitation procedures	0.000	0.398	0.601
N21 Calculus of lower urinary tract	0.000	0.399	0.601
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.399	0.601
G82 Paraplegia and tetraplegia	0.000	0.399	0.600
Z86.7 Personal history of diseases of the circulatory system	0.000	0.401	0.599
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.401	0.599
G91.9 Hydrocephalus, unspecified	0.000	0.402	0.598
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.402	0.598
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.403	0.597
C74 Malignant neoplasm of adrenal gland	0.000	0.403	0.597
K02 Dental caries	0.596	0.404	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.404	0.596
N64.9 Disorder of breast, unspecified	0.000	0.407	0.593
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.407	0.593
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.407	0.593
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.408	0.592
C78.7 Secondary malignant neoplasm of liver	0.000	0.409	0.591
R23 Other skin changes	0.000	0.410	0.590
Z40.9 Prophylactic surgery, unspecified	0.000	0.410	0.590
Z40.8 Other prophylactic surgery	0.000	0.410	0.590
D23.6 Skin of upper limb, including shoulder	0.000	0.411	0.589
R63 Symptoms and signs concerning food and fluid intake	0.000	0.411	0.589
N60.8 Other benign mammary dysplasias	0.000	0.412	0.588
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.413	0.586
G63.2 Diabetic polyneuropathy	0.000	0.414	0.586
Z51.3 Blood transfusion without reported diagnosis	0.000	0.414	0.586
D23.1 Skin of eyelid, including canthus	0.000	0.414	0.586
E11 Non-insulin-dependent diabetes mellitus	0.000	0.417	0.583
C44.7 Skin of lower limb, including hip	0.000	0.418	0.582
Z93.6 Other artificial openings of urinary tract status	0.000	0.419	0.580
N35.8 Other urethral stricture	0.000	0.420	0.580
N35.1 Postinfective urethral stricture, not elsewhere classified	0.000	0.420	0.580
N35.0 Posttraumatic urethral stricture	0.000	0.420	0.580
N36.2 Urethral caruncle	0.000	0.423	0.577
R54 Senility	0.000	0.424	0.575
G81.1 Spastic hemiplegia	0.000	0.424	0.575
G81.0 Flaccid hemiplegia	0.000	0.424	0.575
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.425	0.575
D04 Carcinoma in situ of skin	0.000	0.425	0.575
G80 Infantile cerebral palsy	0.000	0.426	0.574
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.427	0.573
R47.8 Other and unspecified speech disturbances	0.000	0.427	0.573
N64.1 Fat necrosis of breast	0.000	0.427	0.573
K75 Other inflammatory liver diseases	0.572	0.428	0.000
N00-N08 Glomerular diseases	0.000	0.430	0.570
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.431	0.569
K83.8 Other specified diseases of biliary tract	0.569	0.431	0.000
G62 Other polyneuropathies	0.000	0.434	0.566
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.000	0.434	0.565
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.434	0.566
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.434	0.566
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.435	0.565
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.435	0.565
C50.8 Overlapping lesion of breast	0.000	0.435	0.564
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.436	0.564
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.436	0.564
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.436	0.564
Z93.1 Gastrostomy status	0.000	0.436	0.564
D36 Benign neoplasm of other and unspecified sites	0.000	0.437	0.563
N99-N99 Other disorders of the genitourinary system	0.000	0.437	0.563
K76.9 Liver disease, unspecified	0.563	0.437	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.438	0.562
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.438	0.562
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.440	0.560
N13.4 Hydroureter	0.000	0.441	0.559
C18 Malignant neoplasm of colon	0.000	0.443	0.557
R68.3 Clubbing of fingers	0.000	0.444	0.556
R68.2 Dry mouth, unspecified	0.000	0.444	0.556
R68.1 Nonspecific symptoms peculiar to infancy	0.000	0.444	0.556
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.444	0.556
C67.4 Posterior wall of bladder	0.000	0.445	0.555
N64.4 Mastodynia	0.000	0.445	0.555
N64.3 Galactorrhoea not associated with childbirth	0.000	0.445	0.555
N64.2 Atrophy of breast	0.000	0.445	0.555
N64.0 Fissure and fistula of nipple	0.000	0.445	0.555
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.446	0.554
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.446	0.554
K10 Other diseases of jaws	0.554	0.446	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.446	0.553
N27 Small kidney of unknown cause	0.000	0.446	0.553
N25 Disorders resulting from impaired renal tubular function	0.000	0.446	0.553
N26 Unspecified contracted kidney	0.000	0.446	0.553
E11.3 With ophthalmic complications	0.000	0.447	0.553
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.447	0.553
N30.4 Irradiation cystitis	0.000	0.448	0.551
N30.3 Trigonitis	0.000	0.448	0.551
Z93.0 Tracheostomy status	0.000	0.449	0.551
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.449	0.551
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.449	0.550
C70 Malignant neoplasm of meninges	0.000	0.449	0.550
Z93.9 Artificial opening status, unspecified	0.000	0.450	0.550

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations