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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs71435583
log Bayes Factor = 11.0177
Chromosome 2   position 20,924,244  (GRCh37) Explore rs71435583 on Ensembl!
Variant rs71435583 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
I34 Nonrheumatic mitral valve disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I34.0 Mitral (valve) insufficiency
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.997 0.003 0.000
A30-A49 Other bacterial diseases
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
I67 Other cerebrovascular diseases
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
A41 Other septicaemia
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
G90-G99 Other disorders of the nervous system
0.985 0.015 0.000
I60 Subarachnoid haemorrhage
0.985 0.015 0.000
S00-S09 Injuries to the head
0.984 0.016 0.000
S09 Other and unspecified injuries of head
0.979 0.021 0.000
S09.9 Unspecified injury of head
0.976 0.024 0.000
A41.9 Septicaemia, unspecified
0.975 0.025 0.000
I31 Other diseases of pericardium
0.972 0.028 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.972 0.028 0.000
M20-M25 Other joint disorders
0.964 0.036 0.000
M05-M14 Inflammatory polyarthropathies
0.958 0.042 0.000
B25-B34 Other viral diseases
0.958 0.042 0.000
I69 Sequelae of cerebrovascular disease
0.955 0.045 0.000
G91 Hydrocephalus
0.953 0.047 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.952 0.048 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.947 0.053 0.000
I34.1 Mitral (valve) prolapse
0.947 0.053 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.946 0.054 0.000
G93 Other disorders of brain
0.946 0.054 0.000
I67.1 Cerebral aneurysm, nonruptured
0.945 0.055 0.000
J43 Emphysema
0.940 0.060 0.000
M06 Other rheumatoid arthritis
0.938 0.062 0.000
Chapter XXII Codes for special purposes
0.937 0.063 0.000
I67.9 Cerebrovascular disease, unspecified
0.933 0.067 0.000
A49 Bacterial infection of unspecified site
0.930 0.070 0.000
G91.9 Hydrocephalus, unspecified
0.929 0.071 0.000
I31.9 Disease of pericardium, unspecified
0.929 0.071 0.000
B34 Viral infection of unspecified site
0.928 0.072 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.926 0.074 0.000
I47 Paroxysmal tachycardia
0.919 0.081 0.000
B95-B98 Bacterial, viral and other infectious agents
0.918 0.082 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.905 0.095 0.000
B34.9 Viral infection, unspecified
0.902 0.098 0.000
G93.8 Other specified disorders of brain
0.896 0.104 0.000
O36 Maternal care for other known or suspected foetal problems
0.895 0.105 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.892 0.108 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.891 0.109 0.000
O00-O08 Pregnancy with abortive outcome
0.890 0.110 0.000
J43.9 Emphysema, unspecified
0.887 0.113 0.000
M35 Other systemic involvement of connective tissue
0.881 0.119 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.880 0.120 0.000
M21 Other acquired deformities of limbs
0.879 0.121 0.000
J95-J99 Other diseases of the respiratory system
0.878 0.122 0.000
I38 Endocarditis, valve unspecified
0.877 0.123 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.876 0.124 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.875 0.125 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.875 0.125 0.000
J47 Bronchiectasis
0.873 0.127 0.000
M24 Other specific joint derangements
0.872 0.128 0.000
A49.1 Streptococcal infection, unspecified
0.871 0.129 0.000
G30-G32 Other degenerative diseases of the nervous system
0.871 0.129 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.869 0.131 0.000
T92 Sequelae of injuries of upper limb
0.866 0.133 0.000
G70-G73 Diseases of myoneural junction and muscle
0.866 0.134 0.000
I46 Cardiac arrest
0.865 0.135 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.864 0.136 0.000
B35-B49 Mycoses
0.861 0.139 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.858 0.142 0.000
M06.0 Seronegative rheumatoid arthritis
0.858 0.142 0.000
I31.3 Pericardial effusion (noninflammatory)
0.844 0.156 0.000
I47.1 Supraventricular tachycardia
0.840 0.160 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.840 0.160 0.000
I62 Other nontraumatic intracranial haemorrhage
0.838 0.162 0.000
O36.8 Maternal care for other specified foetal problems
0.838 0.162 0.000
O02 Other abnormal products of conception
0.837 0.163 0.000
O43 Placental disorders
0.834 0.166 0.000
I61 Intracerebral haemorrhage
0.832 0.168 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.829 0.171 0.000
T90 Sequelae of injuries of head
0.824 0.176 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.818 0.182 0.000
I05-I09 Chronic rheumatic heart diseases
0.815 0.185 0.000
O02.1 Missed abortion
0.814 0.186 0.000
O80-O84 Delivery
0.810 0.190 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.807 0.193 0.000
M06.9 Rheumatoid arthritis, unspecified
0.806 0.194 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.805 0.195 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.801 0.199 0.000
M60-M63 Disorders of muscles
0.798 0.202 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.797 0.202 0.000
I30 Acute pericarditis
0.797 0.203 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.797 0.203 0.000
G40-G47 Episodic and paroxysmal disorders
0.796 0.204 0.000
U80 Agent resistant to penicillin and related antibiotics
0.796 0.204 0.000
M35.3 Polymyalgia rheumatica
0.795 0.205 0.000
A40 Streptococcal septicaemia
0.795 0.205 0.000
I46.0 Cardiac arrest with successful resuscitation
0.795 0.205 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.794 0.206 0.000
M06.3 Rheumatoid nodule
0.792 0.208 0.000
B15-B19 Viral hepatitis
0.788 0.212 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.786 0.214 0.000
T79-T79 Certain early complications of trauma
0.786 0.214 0.000
O36.9 Maternal care for foetal problem, unspecified
0.786 0.214 0.000
J42 Unspecified chronic bronchitis
0.785 0.215 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.785 0.215 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.782 0.218 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.782 0.218 0.000
B44 Aspergillosis
0.781 0.219 0.000
T93 Sequelae of injuries of lower limb
0.780 0.220 0.000
M80-M85 Disorders of bone density and structure
0.779 0.221 0.000
G93.9 Disorder of brain, unspecified
0.778 0.221 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.778 0.222 0.000
S05 Injury of eye and orbit
0.777 0.222 0.000
I67.2 Cerebral atherosclerosis
0.775 0.225 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.775 0.225 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.775 0.225 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.773 0.227 0.000
A65-A69 Other spirochaetal diseases
0.772 0.227 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.772 0.228 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.772 0.228 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.769 0.231 0.000
S02 Fracture of skull and facial bones
0.768 0.232 0.000
M30 Polyarteritis nodosa and related conditions
0.768 0.232 0.000
G93.6 Cerebral oedema
0.768 0.232 0.000
M33 Dermatopolymyositis
0.766 0.234 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.766 0.234 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.764 0.236 0.000
M70-M79 Other soft tissue disorders
0.764 0.236 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.763 0.237 0.000
G70 Myasthenia gravis and other myoneural disorders
0.762 0.238 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.761 0.239 0.000
M06.4 Inflammatory polyarthropathy
0.761 0.239 0.000
S00 Superficial injury of head
0.760 0.240 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.760 0.240 0.000
O40 Polyhydramnios
0.760 0.240 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.758 0.242 0.000
O33 Maternal care for known or suspected disproportion
0.758 0.242 0.000
Q60-Q64 Congenital malformations of the urinary system
0.757 0.243 0.000
O44 Placenta praevia
0.757 0.243 0.000
B50-B64 Protozoal diseases
0.755 0.245 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.754 0.246 0.000
J46 Status asthmaticus
0.750 0.250 0.000
I67.8 Other specified cerebrovascular diseases
0.750 0.250 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.749 0.251 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.749 0.251 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.747 0.253 0.000
O30 Multiple gestation
0.747 0.253 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.746 0.254 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.746 0.254 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.745 0.255 0.000
G03 Meningitis due to other and unspecified causes
0.744 0.256 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.743 0.257 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.743 0.257 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.740 0.260 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.739 0.260 0.000
M13 Other arthritis
0.739 0.260 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.737 0.263 0.000
A49.0 Staphylococcal infection, unspecified
0.734 0.266 0.000
I60.8 Other subarachnoid haemorrhage
0.732 0.268 0.000
G20-G26 Extrapyramidal and movement disorders
0.731 0.269 0.000
J40 Bronchitis, not specified as acute or chronic
0.729 0.271 0.000
M05 Seropositive rheumatoid arthritis
0.727 0.273 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.727 0.273 0.000
O43.8 Other placental disorders
0.727 0.273 0.000
M31 Other necrotising vasculopathies
0.726 0.273 0.000
M07 Psoriatic and enteropathic arthropathies
0.726 0.274 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.726 0.274 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.726 0.274 0.000
I33 Acute and subacute endocarditis
0.724 0.276 0.000
B34.4 Papovirus infection, unspecified
0.723 0.276 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
J43.2 Centrilobular emphysema
0.722 0.278 0.000
M21.6 Other acquired deformities of ankle and foot
0.722 0.278 0.000
M45-M49 Spondylopathies
0.721 0.279 0.000
Q28 Other congenital malformations of circulatory system
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.716 0.283 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.716 0.283 0.000
G90 Disorders of autonomic nervous system
0.716 0.284 0.000
A48 Other bacterial diseases, not elsewhere classified
0.715 0.285 0.000
A44 Bartonellosis
0.715 0.285 0.000
A43 Nocardiosis
0.715 0.285 0.000
A42 Actinomycosis
0.715 0.285 0.000
A39 Meningococcal infection
0.715 0.285 0.000
A37 Whooping cough
0.715 0.285 0.000
A36 Diphtheria
0.715 0.285 0.000
A32 Listeriosis
0.715 0.285 0.000
A31 Infection due to other mycobacteria
0.715 0.285 0.000
A30 Leprosy [Hansen's disease]
0.715 0.285 0.000
A38 Scarlet fever
0.715 0.285 0.000
A35 Other tetanus
0.715 0.285 0.000
A34 Obstetrical tetanus
0.715 0.285 0.000
A33 Tetanus neonatorum
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.286 0.000
J00-J06 Acute upper respiratory infections
0.712 0.288 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.711 0.289 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.711 0.289 0.000
I67.5 Moyamoya disease
0.711 0.289 0.000
I67.4 Hypertensive encephalopathy
0.711 0.289 0.000
I67.3 Progressive vascular leukoencephalopathy
0.711 0.289 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.711 0.289 0.000
A41.8 Other specified septicaemia
0.709 0.291 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
B44.1 Other pulmonary aspergillosis
0.709 0.291 0.000
A41.4 Septicaemia due to anaerobes
0.709 0.291 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.709 0.291 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.709 0.291 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.709 0.291 0.000
G93.0 Cerebral cysts
0.708 0.292 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.706 0.293 0.000
G92 Toxic encephalopathy
0.706 0.293 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.706 0.294 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.706 0.294 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.706 0.294 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.706 0.294 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.706 0.294 0.000
M21.0 Valgus deformity, not elsewhere classified
0.706 0.294 0.000
S08 Traumatic amputation of part of head
0.705 0.294 0.000
S07 Crushing injury of head
0.705 0.294 0.000
S04 Injury of cranial nerves
0.705 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.294 0.000
I37 Pulmonary valve disorders
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.705 0.295 0.000
M20 Acquired deformities of fingers and toes
0.702 0.298 0.000
T92.1 Sequelae of fracture of arm
0.702 0.298 0.000
S09.7 Multiple injuries of head
0.702 0.298 0.000
S09.2 Traumatic rupture of ear drum
0.702 0.298 0.000
S09.1 Injury of muscle and tendon of head
0.702 0.298 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.702 0.298 0.000
M40-M43 Deforming dorsopathies
0.701 0.299 0.000
I47.0 Reentry ventricular arrhythmia
0.701 0.299 0.000
G91.1 Obstructive hydrocephalus
0.701 0.299 0.000
A49.9 Bacterial infection, unspecified
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.700 0.300 0.000
M21.7 Unequal limb length (acquired)
0.700 0.300 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.700 0.300 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.698 0.302 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.697 0.303 0.000
I31.8 Other specified diseases of pericardium
0.697 0.303 0.000
I31.2 Haemopericardium, not elsewhere classified
0.697 0.303 0.000
I31.1 Chronic constrictive pericarditis
0.697 0.303 0.000
I31.0 Chronic adhesive pericarditis
0.697 0.303 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.697 0.303 0.000
O85-O92 Complications predominantly related to the puerperium
0.696 0.304 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.696 0.304 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.695 0.304 0.000
O00 Ectopic pregnancy
0.695 0.305 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.695 0.305 0.000
M34 Systemic sclerosis
0.695 0.305 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
Q27 Other congenital malformations of peripheral vascular system
0.693 0.307 0.000
M21.3 Wrist or foot drop (acquired)
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.691 0.309 0.000
M32 Systemic lupus erythematosus
0.691 0.309 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.690 0.310 0.000
G81 Hemiplegia
0.690 0.310 0.000
S06 Intracranial injury
0.689 0.311 0.000
G70.0 Myasthenia gravis
0.688 0.312 0.000
M22 Disorders of patella
0.687 0.313 0.000
M12 Other specific arthropathies
0.687 0.313 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.687 0.313 0.000
M08 Juvenile arthritis
0.687 0.313 0.000
B33 Other viral diseases, not elsewhere classified
0.687 0.313 0.000
B30 Viral conjunctivitis
0.687 0.313 0.000
B27 Infectious mononucleosis
0.687 0.313 0.000
B26 Mumps
0.687 0.313 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.686 0.314 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.685 0.315 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.685 0.315 0.000
G91.8 Other hydrocephalus
0.684 0.316 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.684 0.316 0.000
G91.2 Normal-pressure hydrocephalus
0.684 0.316 0.000
G91.0 Communicating hydrocephalus
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.681 0.319 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.681 0.319 0.000
B25 Cytomegaloviral disease
0.680 0.320 0.000
O45 Premature separation of placenta [abruptio placentae]
0.679 0.321 0.000
O31 Complications specific to multiple gestation
0.679 0.321 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.679 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.679 0.321 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.679 0.321 0.000
T95 Sequelae of burns, corrosions and frostbite
0.679 0.321 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.679 0.321 0.000
U80.1 Methicillin resistant agent
0.678 0.322 0.000
G41 Status epilepticus
0.678 0.322 0.000
J81 Pulmonary oedema
0.678 0.322 0.000
G93.7 Reye's syndrome
0.678 0.322 0.000
G93.5 Compression of brain
0.678 0.322 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.676 0.324 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.675 0.324 0.000
I50 Heart failure
0.675 0.325 0.000
I08 Multiple valve diseases
0.675 0.325 0.000
B49 Unspecified mycosis
0.675 0.325 0.000
I36 Nonrheumatic tricuspid valve disorders
0.674 0.325 0.000
O36.4 Maternal care for intra-uterine death
0.675 0.325 0.000
J43.8 Other emphysema
0.674 0.326 0.000
J43.1 Panlobular emphysema
0.674 0.326 0.000
J43.0 MacLeod's syndrome
0.674 0.326 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
Q80-Q89 Other congenital malformations
0.673 0.327 0.000
M06.8 Other specified rheumatoid arthritis
0.672 0.327 0.000
M06.2 Rheumatoid bursitis
0.672 0.327 0.000
M06.1 Adult-onset Still's disease
0.672 0.327 0.000
G71 Primary disorders of muscles
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
A80-A89 Viral infections of the central nervous system
0.671 0.329 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.670 0.330 0.000
M85 Other disorders of bone density and structure
0.669 0.331 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.669 0.331 0.000
M14 Arthropathies in other diseases classified elsewhere
0.669 0.331 0.000
A49.3 Mycoplasma infection, unspecified
0.667 0.333 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.667 0.333 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.667 0.333 0.000
M35.1 Other overlap syndromes
0.667 0.333 0.000
G96 Other disorders of central nervous system
0.666 0.333 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.666 0.334 0.000
B34.8 Other viral infections of unspecified site
0.666 0.334 0.000
B34.3 Parvovirus infection, unspecified
0.666 0.334 0.000
B34.2 Coronavirus infection, unspecified
0.666 0.334 0.000
B34.1 Enterovirus infection, unspecified
0.666 0.334 0.000
B34.0 Adenovirus infection, unspecified
0.666 0.334 0.000
J95.8 Other postprocedural respiratory disorders
0.664 0.336 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O97 Death from sequelae of direct obstetric causes
0.664 0.336 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.664 0.336 0.000
O95 Obstetric death of unspecified cause
0.664 0.336 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.664 0.336 0.000
T92.0 Sequelae of open wound of upper limb
0.664 0.336 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.664 0.336 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.663 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.663 0.337 0.000
O81 Single delivery by forceps and vacuum extractor
0.663 0.337 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.661 0.339 0.000
M62 Other disorders of muscle
0.661 0.339 0.000
O21 Excessive vomiting in pregnancy
0.660 0.340 0.000
Q12 Congenital lens malformations
0.659 0.341 0.000
G03.9 Meningitis, unspecified
0.658 0.342 0.000
M35.7 Hypermobility syndrome
0.657 0.343 0.000
O43.1 Malformation of placenta
0.657 0.343 0.000
B35 Dermatophytosis
0.657 0.343 0.000
M35.0 Sicca syndrome [Sjogren]
0.657 0.343 0.000
S02.3 Fracture of orbital floor
0.656 0.344 0.000
S09.8 Other specified injuries of head
0.656 0.344 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.656 0.344 0.000
M11 Other crystal arthropathies
0.656 0.344 0.000
O80 Single spontaneous delivery
0.656 0.344 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.655 0.345 0.000
J09-J18 Influenza and pneumonia
0.655 0.345 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.345 0.000
I47.2 Ventricular tachycardia
0.655 0.345 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.654 0.346 0.000
M21.2 Flexion deformity
0.654 0.346 0.000
O46.9 Antepartum haemorrhage, unspecified
0.654 0.346 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.653 0.347 0.000
T42.4 Benzodiazepines
0.653 0.347 0.000
O12.0 Gestational oedema
0.652 0.347 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.652 0.348 0.000
I30.9 Acute pericarditis, unspecified
0.652 0.348 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.651 0.348 0.000
S00.0 Superficial injury of scalp
0.651 0.349 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.651 0.349 0.000
M91-M94 Chondropathies
0.651 0.349 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.651 0.349 0.000
Chapter VIII Diseases of the ear and mastoid process
0.650 0.350 0.000
M20.4 Other hammer toe(s) (acquired)
0.650 0.350 0.000
M06.34 Rheumatoid nodule (Hand)
0.650 0.350 0.000
O15 Eclampsia
0.649 0.351 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.649 0.351 0.000
O36.5 Maternal care for poor foetal growth
0.648 0.352 0.000
G31.8 Other specified degenerative diseases of nervous system
0.647 0.353 0.000
G80 Infantile cerebral palsy
0.647 0.353 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.647 0.353 0.000
G47 Sleep disorders
0.647 0.353 0.000
O14.1 Severe preeclampsia
0.646 0.354 0.000
Q66 Congenital deformities of feet
0.646 0.354 0.000
S20-S29 Injuries to the thorax
0.646 0.354 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.645 0.355 0.000
M79.6 Pain in limb
0.644 0.356 0.000
S70-S79 Injuries to the hip and thigh
0.644 0.356 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.644 0.356 0.000
B65-B83 Helminthiases
0.643 0.357 0.000
O14.9 Preeclampsia, unspecified
0.643 0.357 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.642 0.358 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.642 0.358 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.642 0.358 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.642 0.358 0.000
O36.2 Maternal care for hydrops foetalis
0.642 0.358 0.000
O36.1 Maternal care for other isoimmunisation
0.642 0.358 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.642 0.358 0.000
Q61 Cystic kidney disease
0.641 0.359 0.000
U81.0 Vancomycin resistant agent
0.641 0.359 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.641 0.359 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.639 0.360 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.639 0.361 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.639 0.361 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.638 0.362 0.000
O07 Failed attempted abortion
0.638 0.362 0.000
O06 Unspecified abortion
0.638 0.362 0.000
O05 Other abortion
0.638 0.362 0.000
O01 Hydatidiform mole
0.638 0.362 0.000
O41 Other disorders of amniotic fluid and membranes
0.634 0.366 0.000
A40.8 Other streptococcal septicaemia
0.633 0.367 0.000
T93.2 Sequelae of other fractures of lower limb
0.632 0.368 0.000
M20.1 Hallux valgus (acquired)
0.632 0.368 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.632 0.368 0.000
M35.8 Other specified systemic involvement of connective tissue
0.632 0.368 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.632 0.368 0.000
M35.5 Multifocal fibrosclerosis
0.632 0.368 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.632 0.368 0.000
M35.2 Behcet's disease
0.632 0.368 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.632 0.368 0.000
M24.2 Disorder of ligament
0.631 0.368 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.631 0.369 0.000
Q23 Congenital malformations of aortic and mitral valves
0.631 0.369 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.631 0.369 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.631 0.369 0.000
G30 Alzheimer's disease
0.630 0.370 0.000
M21.9 Acquired deformity of limb, unspecified
0.630 0.370 0.000
M21.8 Other specified acquired deformities of limbs
0.630 0.370 0.000
M21.4 Flat foot [pes planus] (acquired)
0.630 0.370 0.000
J96 Respiratory failure, not elsewhere classified
0.629 0.371 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.629 0.371 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.628 0.372 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.628 0.372 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.628 0.372 0.000
Q24 Other congenital malformations of heart
0.628 0.372 0.000
U50 Level of care administered to neonates
0.627 0.372 0.000
U07 Emergency use of U07
0.627 0.372 0.000
U06 Emergency use of U06
0.627 0.372 0.000
U04 Severe acute respiratory syndrome [SARS]
0.627 0.372 0.000
U52 First in a series of a regular day/night admissions
0.627 0.372 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.627 0.373 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.627 0.373 0.000
G31.0 Circumscribed brain atrophy
0.626 0.374 0.000
M24.9 Joint derangement, unspecified
0.625 0.374 0.000
M24.7 Protrusio acetabuli
0.625 0.374 0.000
M24.6 Ankylosis of joint
0.625 0.374 0.000
M24.5 Contracture of joint
0.625 0.374 0.000
M65-M68 Disorders of synovium and tendon
0.625 0.375 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.625 0.375 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.624 0.375 0.000
S02.4 Fracture of malar and maxillary bones
0.623 0.377 0.000
S40-S49 Injuries to the shoulder and upper arm
0.623 0.377 0.000
O33.9 Maternal care for disproportion, unspecified
0.622 0.378 0.000
U51 Admission status on psychiatric patients
0.622 0.378 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.621 0.379 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.621 0.379 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.621 0.379 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.621 0.379 0.000
I46.1 Sudden cardiac death, so described
0.620 0.380 0.000
T90.8 Sequelae of other specified injuries of head
0.620 0.380 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.620 0.380 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.620 0.380 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.620 0.380 0.000
G00 Bacterial meningitis, not elsewhere classified
0.620 0.380 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.620 0.380 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.620 0.380 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.620 0.380 0.000
J02 Acute pharyngitis
0.618 0.382 0.000
T90.9 Sequelae of unspecified injury of head
0.618 0.382 0.000
I61.8 Other intracerebral haemorrhage
0.617 0.382 0.000
M24.0 Loose body in joint
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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