TreeWAS – Variant ID: rs7215286

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.037	0.963	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.036	0.964	0.000
C78.2 Secondary malignant neoplasm of pleura	0.033	0.967	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.032	0.968	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.031	0.969	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.030	0.970	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.030	0.970	0.000
C78.0 Secondary malignant neoplasm of lung	0.028	0.972	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.026	0.973	0.000
C78.7 Secondary malignant neoplasm of liver	0.026	0.974	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.021	0.979	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.020	0.980	0.000
S80-S89 Injuries to the knee and lower leg	0.020	0.980	0.000
S82 Fracture of lower leg, including ankle	0.019	0.981	0.000
S82.5 Fracture of medial malleolus	0.018	0.982	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.018	0.982	0.000
S82.50 Fracture of medial malleolus (closed)	0.018	0.982	0.000
S80 Superficial injury of lower leg	0.017	0.983	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.017	0.983	0.000
S82.3 Fracture of lower end of tibia	0.017	0.983	0.000
S82.2 Fracture of shaft of tibia	0.017	0.983	0.000
S83.2 Tear of meniscus, current	0.016	0.984	0.000
S89 Other and unspecified injuries of lower leg	0.015	0.985	0.000
S83.7 Injury to multiple structures of knee	0.015	0.985	0.000
S83.3 Tear of articular cartilage of knee, current	0.015	0.985	0.000
S83.1 Dislocation of knee	0.015	0.985	0.000
S83.0 Dislocation of patella	0.015	0.985	0.000
S80.8 Other superficial injuries of lower leg	0.015	0.985	0.000
S81 Open wound of lower leg	0.015	0.985	0.000
S82.30 Fracture of lower end of tibia (closed)	0.015	0.985	0.000
S82.6 Fracture of lateral malleolus	0.015	0.985	0.000
S82.20 Fracture of shaft of tibia (closed)	0.014	0.986	0.000
S88 Traumatic amputation of lower leg	0.014	0.986	0.000
S87 Crushing injury of lower leg	0.014	0.986	0.000
S86 Injury of muscle and tendon at lower leg level	0.014	0.986	0.000
S85 Injury of blood vessels at lower leg level	0.014	0.986	0.000
S84 Injury of nerves at lower leg level	0.014	0.986	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.014	0.986	0.000
S80.7 Multiple superficial injuries of lower leg	0.014	0.986	0.000
S82.1 Fracture of upper end of tibia	0.014	0.986	0.000
S82.9 Fracture of lower leg, part unspecified	0.014	0.986	0.000
S82.7 Multiple fractures of lower leg	0.014	0.986	0.000
S82.0 Fracture of patella	0.013	0.987	0.000
S82.4 Fracture of fibula alone	0.013	0.987	0.000
S82.51 Fracture of medial malleolus (open)	0.013	0.987	0.000
S80.0 Contusion of knee	0.013	0.987	0.000
S81.9 Open wound of lower leg, part unspecified	0.013	0.987	0.000
R42 Dizziness and giddiness	0.013	0.987	0.000
S82.21 Fracture of shaft of tibia (open)	0.013	0.987	0.000
K90.0 Coeliac disease	0.013	0.987	0.000
S82.31 Fracture of lower end of tibia (open)	0.012	0.988	0.000
S89.8 Other specified injuries of lower leg	0.012	0.988	0.000
S89.9 Unspecified injury of lower leg	0.011	0.988	0.000
S82.60 Fracture of lateral malleolus (closed)	0.011	0.989	0.000
S89.7 Multiple injuries of lower leg	0.011	0.989	0.000
S89.1 Other specified injuries of lower leg	0.011	0.989	0.000
S89.0 Multiple injuries of lower leg	0.011	0.989	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.011	0.989	0.000
S81.7 Multiple open wounds of lower leg	0.011	0.989	0.000
S82.61 Fracture of lateral malleolus (open)	0.011	0.989	0.000
S81.0 Open wound of knee	0.011	0.989	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.010	0.989	0.000
S84.8 Injury of other nerves at lower leg level	0.010	0.989	0.000
S84.7 Injury of multiple nerves at lower leg level	0.010	0.989	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.010	0.989	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.010	0.989	0.000
S84.0 Injury of tibial nerve at lower leg level	0.010	0.989	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.010	0.989	0.000
S85.8 Injury of other blood vessels at lower leg level	0.010	0.989	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.010	0.989	0.000
S85.5 Injury of popliteal vein	0.010	0.989	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.010	0.989	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.010	0.989	0.000
S85.2 Injury of peroneal artery	0.010	0.989	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.010	0.989	0.000
S85.0 Injury of popliteal artery	0.010	0.989	0.000
S86.0 Injury of Achilles tendon	0.010	0.989	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.010	0.989	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.010	0.989	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.010	0.989	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.010	0.989	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.010	0.989	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.010	0.989	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.010	0.989	0.000
S87.0 Crushing injury of knee	0.010	0.989	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.010	0.989	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.010	0.989	0.000
S88.0 Traumatic amputation at knee level	0.010	0.989	0.000
S82.11 Fracture of upper end of tibia (open)	0.010	0.990	0.000
S82.10 Fracture of upper end of tibia (closed)	0.010	0.990	0.000
S82.71 Multiple fractures of lower leg (open)	0.010	0.990	0.000
S82.70 Multiple fractures of lower leg (closed)	0.010	0.990	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.010	0.990	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.010	0.990	0.000
S82.01 Fracture of patella (open)	0.010	0.990	0.000
S82.41 Fracture of fibula alone (open)	0.010	0.990	0.000
S82.8 Fractures of other parts of lower leg	0.010	0.990	0.000
S82.00 Fracture of patella (closed)	0.009	0.991	0.000
S82.40 Fracture of fibula alone (closed)	0.009	0.991	0.000
C79 Secondary malignant neoplasm of other sites	0.009	0.991	0.000
S81.8 Open wound of other parts of lower leg	0.009	0.991	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.009	0.991	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.008	0.992	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.008	0.992	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.008	0.992	0.000
S80.9 Superficial injury of lower leg, unspecified	0.008	0.992	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.008	0.992	0.000
S86.00 Unspecified injury of Achilles tendon	0.008	0.992	0.000
C80 Malignant neoplasm without specification of site	0.008	0.992	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.008	0.992	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.007	0.993	0.000
R41.3 Other amnesia	0.007	0.993	0.000
S82.86 Maisonneuve's fracture	0.007	0.993	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.007	0.993	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.007	0.993	0.000
S82.81 Fractures of other parts of lower leg (open)	0.007	0.993	0.000
C79.2 Secondary malignant neoplasm of skin	0.007	0.993	0.000
C80.9 Malignant neoplasm, unspecified	0.007	0.993	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.007	0.993	0.000
D35.2 Pituitary gland	0.007	0.993	0.000
R46 Symptoms and signs involving appearance and behaviour	0.007	0.993	0.000
R43 Disturbances of smell and taste	0.006	0.993	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.006	0.993	0.000
R45 Symptoms and signs involving emotional state	0.006	0.994	0.000
R41.2 Retrograde amnesia	0.006	0.994	0.000
R41.1 Anterograde amnesia	0.006	0.994	0.000
C79.6 Secondary malignant neoplasm of ovary	0.006	0.994	0.000
R40 Somnolence, stupor and coma	0.006	0.994	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.006	0.994	0.000
C76.7 Other ill-defined sites	0.006	0.994	0.000
C76.5 Lower limb	0.006	0.994	0.000
C76.4 Upper limb	0.006	0.994	0.000
C76.3 Pelvis	0.006	0.994	0.000
C76.2 Abdomen	0.006	0.994	0.000
C76.1 Thorax	0.006	0.994	0.000
C76.0 Head, face and neck	0.006	0.994	0.000
R44.0 Auditory hallucinations	0.006	0.994	0.000
K90 Intestinal malabsorption	0.006	0.994	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.006	0.994	0.000
R44.1 Visual hallucinations	0.005	0.995	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.005	0.995	0.000
R44.2 Other hallucinations	0.005	0.995	0.000
R45.8 Other symptoms and signs involving emotional state	0.005	0.995	0.000
R41.0 Disorientation, unspecified	0.005	0.995	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.005	0.995	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.005	0.995	0.000
R46.6 Undue concern and preoccupation with stressful events	0.005	0.995	0.000
R46.5 Suspiciousness and marked evasiveness	0.005	0.995	0.000
R46.4 Slowness and poor responsiveness	0.005	0.995	0.000
R46.3 Overactivity	0.005	0.995	0.000
R46.2 Strange and inexplicable behaviour	0.005	0.995	0.000
R46.1 Bizarre personal appearance	0.005	0.995	0.000
R46.0 Very low level of personal hygiene	0.005	0.995	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.005	0.995	0.000
R43.2 Parageusia	0.005	0.995	0.000
R43.1 Parosmia	0.005	0.995	0.000
R43.0 Anosmia	0.005	0.995	0.000
R44.3 Hallucinations, unspecified	0.005	0.995	0.000
R40.0 Somnolence	0.005	0.995	0.000
N30.2 Other chronic cystitis	0.000	0.995	0.005
D35 Benign neoplasm of other and unspecified endocrine glands	0.005	0.995	0.000
D12.6 Colon, unspecified	0.005	0.995	0.000
R45.7 State of emotional shock and stress, unspecified	0.005	0.995	0.000
R45.6 Physical violence	0.005	0.995	0.000
R45.5 Hostility	0.005	0.995	0.000
R45.4 Irritability and anger	0.005	0.995	0.000
R45.3 Demoralisation and apathy	0.005	0.995	0.000
R45.2 Unhappiness	0.005	0.995	0.000
R45.0 Nervousness	0.005	0.995	0.000
R40.1 Stupor	0.005	0.995	0.000
K90.8 Other intestinal malabsorption	0.004	0.995	0.000
K90.3 Pancreatic steatorrhoea	0.004	0.995	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.004	0.995	0.000
K90.1 Tropical sprue	0.004	0.995	0.000
D22 Melanocytic naevi	0.005	0.995	0.000
C15-C26 Malignant neoplasms of digestive organs	0.005	0.995	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.004	0.995	0.000
C20 Malignant neoplasm of rectum	0.005	0.995	0.000
K90.9 Intestinal malabsorption, unspecified	0.004	0.995	0.000
L72.1 Trichilemmal cyst	0.000	0.995	0.005
D22.4 Melanocytic naevi of scalp and neck	0.004	0.996	0.000
D22.5 Melanocytic naevi of trunk	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
S02 Fracture of skull and facial bones	0.004	0.996	0.000
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.004	0.996	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.004	0.996	0.000
D10-D36 Benign neoplasms	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
S02.2 Fracture of nasal bones	0.004	0.996	0.000
S02.3 Fracture of orbital floor	0.004	0.996	0.000
D12.7 Rectosigmoid junction	0.004	0.996	0.000
S02.30 Fracture of orbital floor (closed)	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
S63.6 Sprain and strain of finger(s)	0.004	0.996	0.000
D30 Benign neoplasm of urinary organs	0.004	0.996	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.004	0.996	0.000
D23 Other benign neoplasms of skin	0.004	0.996	0.000
D23.5 Skin of trunk	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.004	0.996	0.000
C25.1 Body of pancreas	0.004	0.996	0.000
C21 Malignant neoplasm of anus and anal canal	0.004	0.996	0.000
C43.5 Malignant melanoma of trunk	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
R45.1 Restlessness and agitation	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.004	0.996	0.000
D30.0 Kidney	0.004	0.996	0.000
D16 Benign neoplasm of bone and articular cartilage	0.004	0.996	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.996	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.004	0.996	0.000
D35.9 Endocrine gland, unspecified	0.004	0.996	0.000
D35.8 Pluriglandular involvement	0.004	0.996	0.000
D35.7 Other specified endocrine glands	0.004	0.996	0.000
D35.6 Aortic body and other paraganglia	0.004	0.996	0.000
D35.5 Carotid body	0.004	0.996	0.000
D35.4 Pineal gland	0.004	0.996	0.000
D35.3 Craniopharyngeal duct	0.004	0.996	0.000
D26 Other benign neoplasms of uterus	0.004	0.996	0.000
C21.0 Anus, unspecified	0.004	0.996	0.000
R40.2 Coma, unspecified	0.004	0.996	0.000
C43 Malignant melanoma of skin	0.004	0.996	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.004	0.996	0.000
S62 Fracture at wrist and hand level	0.004	0.996	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.004	0.996	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.996	0.004
D22.2 Melanocytic naevi of ear and external auricular canal	0.004	0.996	0.000
D23.4 Skin of scalp and neck	0.004	0.996	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.004	0.996	0.000
D23.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.004	0.996	0.000
D35.0 Adrenal gland	0.004	0.996	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.004	0.996	0.000
D10 Benign neoplasm of mouth and pharynx	0.004	0.996	0.000
Chapter II Neoplasms	0.004	0.996	0.000
D36 Benign neoplasm of other and unspecified sites	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.003	0.996	0.000
C17 Malignant neoplasm of small intestine	0.003	0.996	0.000
C23 Malignant neoplasm of gallbladder	0.003	0.996	0.000
D22.9 Melanocytic naevi, unspecified	0.003	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
S02.6 Fracture of mandible	0.003	0.996	0.000
D12.9 Anus and anal canal	0.004	0.996	0.000
D30.3 Bladder	0.003	0.996	0.000
D23.0 Skin of lip	0.003	0.996	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.003	0.996	0.000
D23.2 Skin of ear and external auricular canal	0.003	0.996	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.003	0.996	0.000
S69 Other and unspecified injuries of wrist and hand	0.003	0.996	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.003	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
S62.6 Fracture of other finger	0.003	0.997	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.003	0.997	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.003	0.997	0.000
D23.9 Skin, unspecified	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
S62.5 Fracture of thumb	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
S02.5 Fracture of tooth	0.003	0.997	0.000
C16.0 Cardia	0.003	0.997	0.000
D12.0 Caecum	0.003	0.997	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.003	0.997	0.000
S64 Injury of nerves at wrist and hand level	0.003	0.997	0.000
T92 Sequelae of injuries of upper limb	0.003	0.997	0.000
S00-S09 Injuries to the head	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.003	0.997	0.000
S63.1 Dislocation finger	0.003	0.997	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.003	0.997	0.000
S63.5 Sprain and strain of wrist	0.003	0.997	0.000
S63.2 Multiple dislocations of fingers	0.003	0.997	0.000
S63.0 Dislocation of wrist	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.003	0.997	0.000
D16.4 Bones of skull and face	0.003	0.997	0.000
D31 Benign neoplasm of eye and adnexa	0.003	0.997	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.003	0.997	0.000
D19 Benign neoplasm of mesothelial tissue	0.003	0.997	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.003	0.997	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.003	0.997	0.000
D16.1 Short bones of upper limb	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
S02.31 Fracture of orbital floor (open)	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.003	0.997	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
D29 Benign neoplasm of male genital organs	0.003	0.997	0.000
S65 Injury of blood vessels at wrist and hand level	0.003	0.997	0.000
S62.50 Fracture of thumb (closed)	0.003	0.997	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.003	0.997	0.000
D22.0 Melanocytic naevi of lip	0.003	0.997	0.000
D26.1 Corpus uteri	0.003	0.997	0.000
D30.9 Urinary organ, unspecified	0.003	0.997	0.000
D30.7 Other urinary organs	0.003	0.997	0.000
D30.4 Urethra	0.003	0.997	0.000
D30.2 Ureter	0.003	0.997	0.000
D30.1 Renal pelvis	0.003	0.997	0.000
D10.1 Tongue	0.003	0.997	0.000
D26.0 Cervix uteri	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.003	0.997	0.000
C01 Malignant neoplasm of base of tongue	0.003	0.997	0.000
C44.2 Skin of ear and external auricular canal	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.003	0.997	0.000
C16.9 Stomach, unspecified	0.003	0.997	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.003	0.997	0.000
C21.2 Cloacogenic zone	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
D33.2 Brain, unspecified	0.003	0.997	0.000
S60 Superficial injury of wrist and hand	0.003	0.997	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.003	0.997	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.003	0.997	0.000
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
C16.4 Pylorus	0.003	0.997	0.000
C16.3 Pyloric antrum	0.003	0.997	0.000
C16.2 Body of stomach	0.003	0.997	0.000
C16.1 Fundus of stomach	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.003	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
D16.9 Bone and articular cartilage, unspecified	0.003	0.997	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.003	0.997	0.000
D16.7 Ribs, sternum and clavicle	0.003	0.997	0.000
D16.6 Vertebral column	0.003	0.997	0.000
D16.5 Lower jaw bone	0.003	0.997	0.000
D16.3 Short bones of lower limb	0.003	0.997	0.000
D16.2 Long bones of lower limb	0.003	0.997	0.000
D16.0 Scapula and long bones of upper limb	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
S00 Superficial injury of head	0.003	0.997	0.000
T18 Foreign body in alimentary tract	0.003	0.997	0.000
T33-T35 Frostbite	0.003	0.997	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.997	0.000
C43.4 Malignant melanoma of scalp and neck	0.003	0.997	0.000
D12.1 Appendix	0.003	0.997	0.000
D26.9 Uterus, unspecified	0.003	0.997	0.000
D26.7 Other parts of uterus	0.003	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
C43.8 Overlapping malignant melanoma of skin	0.003	0.997	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.003	0.997	0.000
C43.0 Malignant melanoma of lip	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.000
T17 Foreign body in respiratory tract	0.003	0.997	0.000
D21.9 Connective and other soft tissue, unspecified	0.003	0.997	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.003	0.997	0.000
D21.5 Connective and other soft tissue of pelvis	0.003	0.997	0.000
D21.4 Connective and other soft tissue of abdomen	0.003	0.997	0.000
D21.3 Connective and other soft tissue of thorax	0.003	0.997	0.000
D35.1 Parathyroid gland	0.003	0.997	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.003	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
S62.60 Fracture of other finger (closed)	0.003	0.997	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.003	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.003	0.997	0.000
C26.1 Spleen	0.003	0.997	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.003	0.997	0.000
T91.3 Sequelae of injury of spinal cord	0.003	0.997	0.000
D32 Benign neoplasm of meninges	0.003	0.997	0.000
D11 Benign neoplasm of major salivary glands	0.003	0.997	0.000
T79-T79 Certain early complications of trauma	0.003	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
D10.9 Pharynx, unspecified	0.003	0.997	0.000
D10.7 Hypopharynx	0.003	0.997	0.000
D10.6 Nasopharynx	0.003	0.997	0.000
D10.5 Other parts of oropharynx	0.003	0.997	0.000
D10.4 Tonsil	0.003	0.997	0.000
D10.2 Floor of mouth	0.003	0.997	0.000
D10.0 Lip	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.003	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.003	0.997	0.000
C18.4 Transverse colon	0.003	0.997	0.000
D36.9 Benign neoplasm of unspecified site	0.003	0.997	0.000
D36.0 Lymph nodes	0.003	0.997	0.000
S62.3 Fracture of other metacarpal bone	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
C17.9 Small intestine, unspecified	0.003	0.997	0.000
C17.8 Overlapping lesion of small intestine	0.003	0.997	0.000
C17.3 Meckel's diverticulum	0.003	0.997	0.000
C17.2 Ileum	0.003	0.997	0.000
C17.1 Jejunum	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
C24.9 Biliary tract, unspecified	0.003	0.997	0.000
C24.8 Overlapping lesion of biliary tract	0.003	0.997	0.000
C24.1 Ampulla of Vater	0.003	0.997	0.000
C24.0 Extrahepatic bile duct	0.003	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
D14.1 Larynx	0.003	0.997	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.003	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.003	0.997	0.000
D14.4 Respiratory system, unspecified	0.003	0.997	0.000
D14.3 Bronchus and lung	0.003	0.997	0.000
D14.2 Trachea	0.003	0.997	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
C18.2 Ascending colon	0.003	0.997	0.000
C22.7 Other specified carcinomas of liver	0.003	0.997	0.000
C22.4 Other sarcomas of liver	0.003	0.997	0.000
C22.3 Angiosarcoma of liver	0.003	0.997	0.000
C22.2 Hepatoblastoma	0.003	0.997	0.000
S69.8 Other specified injuries of wrist and hand	0.003	0.997	0.000
S69.7 Multiple injuries of wrist and hand	0.003	0.997	0.000
C04 Malignant neoplasm of floor of mouth	0.003	0.997	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.997	0.000
D33.9 Central nervous system, unspecified	0.003	0.997	0.000
D33.7 Other specified parts of central nervous system	0.003	0.997	0.000
D33.4 Spinal cord	0.003	0.997	0.000
D33.1 Brain, infratentorial	0.003	0.997	0.000
D33.0 Brain, supratentorial	0.003	0.997	0.000
S00.5 Superficial injury of lip and oral cavity	0.003	0.997	0.000
T18.1 Foreign body in oesophagus	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.997	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.003	0.997	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.003	0.997	0.000
T19 Foreign body in genito-urinary tract	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.003	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
S00.3 Superficial injury of nose	0.003	0.997	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
C43.9 Malignant melanoma of skin, unspecified	0.003	0.997	0.000
D34 Benign neoplasm of thyroid gland	0.003	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.997	0.000
S62.2 Fracture of first metacarpal bone	0.003	0.997	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.003	0.997	0.000
S64.8 Injury of other nerves at wrist and hand level	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.003	0.997	0.000
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.003	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.002	0.997	0.000
D15.9 Intrathoracic organ, unspecified	0.002	0.997	0.000
D15.7 Other specified intrathoracic organs	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations