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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7219021
log Bayes Factor = 3.96297
Chromosome 17   position 46,840,541  (GRCh37) Explore rs7219021 on Ensembl!
Variant rs7219021 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I10-I15 Hypertensive diseases
0.000 0.002 0.998
I10 Essential (primary) hypertension
0.000 0.002 0.998
I30-I52 Other forms of heart disease
0.000 0.004 0.996
I50 Heart failure
0.000 0.011 0.989
I42 Cardiomyopathy
0.000 0.014 0.986
I50.9 Heart failure, unspecified
0.000 0.018 0.982
I44 Atrioventricular and left bundle-branch block
0.000 0.028 0.972
I47 Paroxysmal tachycardia
0.000 0.028 0.972
I44.7 Left bundle-branch block, unspecified
0.000 0.030 0.970
I47.2 Ventricular tachycardia
0.000 0.034 0.966
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.058 0.942
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.059 0.941
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.068 0.932
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.071 0.929
I42.0 Dilated cardiomyopathy
0.000 0.077 0.923
I25.5 Ischaemic cardiomyopathy
0.000 0.080 0.920
I42.2 Other hypertrophic cardiomyopathy
0.000 0.088 0.912
I71 Aortic aneurysm and dissection
0.000 0.093 0.907
I25.3 Aneurysm of heart
0.000 0.104 0.896
I72 Other aneurysm
0.000 0.105 0.895
I60-I69 Cerebrovascular diseases
0.000 0.115 0.885
I50.1 Left ventricular failure
0.000 0.130 0.870
I63 Cerebral infarction
0.000 0.137 0.863
I61 Intracerebral haemorrhage
0.000 0.148 0.852
I21 Acute myocardial infarction
0.000 0.158 0.842
I23 Certain current complications following acute myocardial infarction
0.000 0.162 0.838
I44.2 Atrioventricular block, complete
0.000 0.165 0.835
I21.9 Acute myocardial infarction, unspecified
0.000 0.168 0.832
I36 Nonrheumatic tricuspid valve disorders
0.000 0.170 0.830
I63.8 Other cerebral infarction
0.000 0.172 0.828
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.176 0.824
I99 Other and unspecified disorders of circulatory system
0.000 0.186 0.814
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.187 0.813
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.197 0.803
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.200 0.800
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.201 0.799
I72.4 Aneurysm of artery of lower extremity
0.000 0.206 0.794
I44.3 Other and unspecified atrioventricular block
0.000 0.207 0.793
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.209 0.791
I30 Acute pericarditis
0.000 0.212 0.788
I71.0 Dissection of aorta [any part]
0.000 0.213 0.786
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.214 0.786
I95 Hypotension
0.000 0.224 0.776
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.227 0.773
I65.2 Occlusion and stenosis of carotid artery
0.000 0.238 0.762
I12 Hypertensive renal disease
0.000 0.240 0.760
I47.0 Reentry ventricular arrhythmia
0.000 0.254 0.746
I72.0 Aneurysm of carotid artery
0.000 0.257 0.743
I25.4 Coronary artery aneurysm
0.000 0.263 0.737
I22 Subsequent myocardial infarction
0.000 0.264 0.736
I73 Other peripheral vascular diseases
0.000 0.265 0.735
I72.8 Aneurysm of other specified arteries
0.000 0.271 0.729
I95.2 Hypotension due to drugs
0.000 0.276 0.724
I23.8 Other current complications following acute myocardial infarction
0.000 0.278 0.722
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.284 0.716
I52 Other heart disorders in diseases classified elsewhere
0.000 0.286 0.714
I48 Atrial fibrillation and flutter
0.000 0.286 0.714
I41 Myocarditis in diseases classified elsewhere
0.000 0.286 0.714
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.286 0.714
I32 Pericarditis in diseases classified elsewhere
0.000 0.286 0.714
I72.9 Aneurysm of unspecified site
0.000 0.287 0.713
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.288 0.712
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.293 0.707
I42.5 Other restrictive cardiomyopathy
0.000 0.293 0.707
I42.4 Endocardial fibroelastosis
0.000 0.293 0.707
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.293 0.707
I44.5 Left posterior fascicular block
0.000 0.303 0.697
I11 Hypertensive heart disease
0.000 0.310 0.690
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.312 0.688
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.313 0.687
I42.9 Cardiomyopathy, unspecified
0.000 0.315 0.685
I61.8 Other intracerebral haemorrhage
0.000 0.317 0.683
I13 Hypertensive heart and renal disease
0.000 0.317 0.683
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.318 0.682
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.324 0.676
I00-I02 Acute rheumatic fever
0.000 0.326 0.674
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.329 0.671
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.330 0.670
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.331 0.669
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.336 0.664
I44.4 Left anterior fascicular block
0.000 0.340 0.660
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.342 0.658
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.348 0.652
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.350 0.650
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.350 0.650
I95.1 Orthostatic hypotension
0.000 0.353 0.647
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.358 0.642
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.358 0.642
I72.1 Aneurysm of artery of upper extremity
0.000 0.358 0.642
I63.9 Cerebral infarction, unspecified
0.000 0.361 0.639
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.363 0.637
I95.0 Idiopathic hypotension
0.000 0.364 0.636
I72.2 Aneurysm of renal artery
0.000 0.365 0.635
I37 Pulmonary valve disorders
0.000 0.365 0.635
I30.1 Infective pericarditis
0.000 0.369 0.631
I73.9 Peripheral vascular disease, unspecified
0.000 0.370 0.630
I42.6 Alcoholic cardiomyopathy
0.000 0.375 0.625
I12.0 Hypertensive renal disease with renal failure
0.000 0.376 0.624
I24 Other acute ischaemic heart diseases
0.000 0.378 0.622
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.380 0.620
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.381 0.619
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.381 0.619
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.381 0.619
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.387 0.612
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.391 0.608
I33 Acute and subacute endocarditis
0.000 0.392 0.608
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.396 0.604
I72.3 Aneurysm of iliac artery
0.000 0.398 0.602
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.399 0.601
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.399 0.601
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.399 0.601
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.399 0.601
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.399 0.601
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.399 0.601
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.399 0.601
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.400 0.600
I73.8 Other specified peripheral vascular diseases
0.000 0.404 0.596
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.405 0.595
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.405 0.595
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.405 0.595
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.405 0.595
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.408 0.592
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.409 0.591
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.409 0.591
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.409 0.591
I98.0 Cardiovascular syphilis
0.000 0.409 0.591
I40 Acute myocarditis
0.000 0.411 0.589
I70 Atherosclerosis
0.000 0.423 0.577
I30.9 Acute pericarditis, unspecified
0.000 0.423 0.577
I42.8 Other cardiomyopathies
0.000 0.424 0.576
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.424 0.575
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.424 0.575
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.431 0.569
I30.8 Other forms of acute pericarditis
0.000 0.435 0.565
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.435 0.565
I15 Secondary hypertension
0.000 0.440 0.559
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.443 0.557
I44.6 Other and unspecified fascicular block
0.000 0.444 0.556
I50.0 Congestive heart failure
0.000 0.445 0.555
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.449 0.551
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.470 0.530
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.473 0.527
I68.0 Cerebral amyloid angiopathy
0.000 0.474 0.526
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.484 0.516
I62 Other nontraumatic intracranial haemorrhage
0.000 0.486 0.514
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.487 0.513
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.488 0.512
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.488 0.512
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.488 0.512
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.488 0.512
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.488 0.512
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.488 0.512
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.488 0.512
I48.4 Atypical atrial flutter
0.000 0.488 0.512
I48.3 Typical atrial flutter
0.000 0.488 0.512
I48.2 Chronic atrial fibrillation
0.000 0.488 0.512
I48.1 Persistent atrial fibrillation
0.000 0.488 0.512
I48.0 Paroxysmal atrial fibrillation
0.000 0.488 0.512
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.488 0.512
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.488 0.512
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.489 0.510
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.490 0.510
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.491 0.509
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.498 0.502
I78 Diseases of capillaries
0.000 0.498 0.502
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.502 0.498
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.507 0.493
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.507 0.493
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.507 0.493
I12.9 Hypertensive renal disease without renal failure
0.000 0.510 0.490
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.510 0.489
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.510 0.489
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.510 0.489
I79.1 Aortitis in diseases classified elsewhere
0.000 0.511 0.489
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.511 0.489
I31 Other diseases of pericardium
0.000 0.514 0.486
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.515 0.485
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.515 0.485
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.515 0.485
I02 Rheumatic chorea
0.000 0.517 0.483
I01 Rheumatic fever with heart involvement
0.000 0.517 0.483
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.518 0.481
I74 Arterial embolism and thrombosis
0.000 0.526 0.474
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.533 0.467
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.543 0.457
I37.9 Pulmonary valve disorder, unspecified
0.000 0.545 0.455
I37.8 Other pulmonary valve disorders
0.000 0.545 0.455
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.545 0.455
I37.0 Pulmonary valve stenosis
0.000 0.545 0.455
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.552 0.448
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.555 0.445
I00 Rheumatic fever without mention of heart involvement
0.000 0.559 0.440
I46 Cardiac arrest
0.000 0.568 0.432
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.573 0.427
I65.1 Occlusion and stenosis of basilar artery
0.000 0.574 0.425
I95.8 Other hypotension
0.000 0.576 0.423
I33.0 Acute and subacute infective endocarditis
0.000 0.577 0.423
I40.8 Other acute myocarditis
0.000 0.577 0.422
I40.1 Isolated myocarditis
0.000 0.577 0.422
I70.1 Atherosclerosis of renal artery
0.000 0.586 0.414
I70.9 Generalised and unspecified atherosclerosis
0.000 0.586 0.413
I70.8 Atherosclerosis of other arteries
0.000 0.586 0.413
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.592 0.408
I70.0 Atherosclerosis of aorta
0.000 0.595 0.404
I40.0 Infective myocarditis
0.000 0.598 0.402
I15.8 Other secondary hypertension
0.000 0.599 0.401
I15.2 Hypertension secondary to endocrine disorders
0.000 0.599 0.401
I15.0 Renovascular hypertension
0.000 0.601 0.399
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.608 0.392
I45 Other conduction disorders
0.000 0.608 0.392
I24.1 Dressler's syndrome
0.000 0.608 0.392
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.613 0.386
I22.8 Subsequent myocardial infarction of other sites
0.000 0.615 0.385
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.620 0.380
I34 Nonrheumatic mitral valve disorders
0.000 0.621 0.379
I37.1 Pulmonary valve insufficiency
0.000 0.624 0.376
I69 Sequelae of cerebrovascular disease
0.000 0.624 0.376
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.634 0.365
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.634 0.365
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.634 0.365
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.634 0.365
I77 Other disorders of arteries and arterioles
0.001 0.637 0.362
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.638 0.362
I78.9 Disease of capillaries, unspecified
0.000 0.640 0.360
I62.1 Nontraumatic extradural haemorrhage
0.000 0.641 0.359
I74.5 Embolism and thrombosis of iliac artery
0.000 0.645 0.355
I15.9 Seconday hypertension, unspecified
0.000 0.646 0.354
I31.1 Chronic constrictive pericarditis
0.000 0.648 0.352
I33.9 Acute endocarditis, unspecified
0.000 0.650 0.349
I31.8 Other specified diseases of pericardium
0.000 0.651 0.348
I31.2 Haemopericardium, not elsewhere classified
0.000 0.651 0.348
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.652 0.348
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.653 0.346
I01.8 Other acute rheumatic heart disease
0.000 0.653 0.346
I01.2 Acute rheumatic myocarditis
0.000 0.653 0.346
I01.1 Acute rheumatic endocarditis
0.000 0.653 0.346
I01.0 Acute rheumatic pericarditis
0.000 0.653 0.346
I02.9 Rheumatic chorea without heart involvement
0.000 0.653 0.346
I02.0 Rheumatic chorea with heart involvement
0.000 0.653 0.346
I31.3 Pericardial effusion (noninflammatory)
0.000 0.660 0.340
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.660 0.340
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.670 0.330
I40.9 Acute myocarditis, unspecified
0.001 0.670 0.329
I78.8 Other diseases of capillaries
0.000 0.671 0.328
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.672 0.328
I20 Angina pectoris
0.000 0.674 0.326
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.676 0.324
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.679 0.320
I15.1 Hypertension secondary to other renal disorders
0.000 0.679 0.320
I74.8 Embolism and thrombosis of other arteries
0.000 0.680 0.320
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.689 0.311
I45.3 Trifascicular block
0.000 0.689 0.311
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.689 0.311
I46.1 Sudden cardiac death, so described
0.000 0.690 0.309
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.691 0.309
I45.4 Nonspecific intraventricular block
0.000 0.691 0.309
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.694 0.306
I97.0 Postcardiotomy syndrome
0.000 0.694 0.306
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.698 0.302
I31.0 Chronic adhesive pericarditis
0.000 0.698 0.301
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.699 0.301
I66.3 Occlusion and stenosis of cerebellar arteries
0.001 0.700 0.299
I24.8 Other forms of acute ischaemic heart disease
0.000 0.702 0.298
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.703 0.297
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.703 0.297
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.703 0.296
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.703 0.296
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.703 0.296
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.703 0.296
I77.1 Stricture of artery
0.000 0.705 0.295
I73.0 Raynaud's syndrome
0.000 0.706 0.294
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.708 0.292
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.710 0.290
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.710 0.290
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.710 0.289
I20.0 Unstable angina
0.000 0.712 0.288
I45.9 Conduction disorder, unspecified
0.000 0.712 0.288
I25.2 Old myocardial infarction
0.000 0.714 0.286
I45.0 Right fascicular block
0.000 0.719 0.281
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.719 0.281
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.720 0.280
I77.0 Arteriovenous fistula, acquired
0.001 0.724 0.276
I45.2 Bifascicular block
0.000 0.725 0.275
I69.3 Sequelae of cerebral infarction
0.000 0.726 0.274
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.734 0.266
I97.1 Other functional disturbances following cardiac surgery
0.000 0.735 0.265
I77.5 Necrosis of artery
0.001 0.739 0.259
I77.4 Coeliac artery compression syndrome
0.001 0.739 0.259
I77.3 Arterial fibromuscular dysplasia
0.001 0.739 0.259
I45.8 Other specified conduction disorders
0.000 0.741 0.258
I77.2 Rupture of artery
0.001 0.749 0.250
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.751 0.249
I45.6 Preexcitation syndrome
0.000 0.755 0.245
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.755 0.245
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.766 0.234
I28 Other diseases of pulmonary vessels
0.000 0.769 0.231
I31.9 Disease of pericardium, unspecified
0.000 0.777 0.223
I46.0 Cardiac arrest with successful resuscitation
0.000 0.788 0.212
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.788 0.212
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.788 0.211
I45.5 Other specified heart block
0.000 0.793 0.207
I46.9 Cardiac arrest, unspecified
0.000 0.794 0.206
I38 Endocarditis, valve unspecified
0.000 0.798 0.201
I05-I09 Chronic rheumatic heart diseases
0.001 0.803 0.197
I77.8 Other specified disorders of arteries and arterioles
0.001 0.809 0.190
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.813 0.187
I97.2 Postmastectomy lymphoedema syndrome
0.001 0.813 0.186
I80 Phlebitis and thrombophlebitis
0.000 0.813 0.187
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.814 0.186
I78.1 Naevus, nonneoplastic
0.000 0.815 0.185
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.815 0.185
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.823 0.177
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.823 0.177
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.826 0.174
I28.8 Other specified diseases of pulmonary vessels
0.000 0.827 0.173
I82 Other venous embolism and thrombosis
0.000 0.828 0.172
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.829 0.170
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.834 0.166
I28.1 Aneurysm of pulmonary artery
0.000 0.834 0.166
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.834 0.166
I85 Oesophageal varices
0.000 0.837 0.163
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.850 0.150
I87 Other disorders of veins
0.000 0.852 0.148
I83 Varicose veins of lower extremities
0.000 0.853 0.147
I20.8 Other forms of angina pectoris
0.000 0.859 0.141
I09 Other rheumatic heart diseases
0.001 0.862 0.138
I51 Complications and ill-defined descriptions of heart disease
0.000 0.863 0.137
I85.0 Oesophageal varices with bleeding
0.000 0.865 0.135
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.867 0.133
I81 Portal vein thrombosis
0.000 0.868 0.132
I35 Nonrheumatic aortic valve disorders
0.000 0.873 0.127
I82.2 Embolism and thrombosis of vena cava
0.000 0.874 0.126
I06 Rheumatic aortic valve diseases
0.001 0.874 0.125
I82.3 Embolism and thrombosis of renal vein
0.000 0.876 0.123
I82.1 Thrombophlebitis migrans
0.000 0.876 0.123
I82.0 Budd-Chiari syndrome
0.000 0.876 0.123
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.878 0.122
I07 Rheumatic tricuspid valve diseases
0.000 0.881 0.119
I86 Varicose veins of other sites
0.000 0.882 0.118
I88 Nonspecific lymphadenitis
0.000 0.883 0.116
I20.9 Angina pectoris, unspecified
0.000 0.884 0.116
I67 Other cerebrovascular diseases
0.000 0.885 0.115
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.886 0.114
I44.0 Atrioventricular block, first degree
0.000 0.890 0.110
I05 Rheumatic mitral valve diseases
0.000 0.890 0.109
I26 Pulmonary embolism
0.000 0.890 0.109
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.893 0.107
I87.9 Disorder of vein, unspecified
0.000 0.894 0.106
I87.0 Postphlebitic syndrome
0.000 0.894 0.106
I82.8 Embolism and thrombosis of other specified veins
0.000 0.894 0.106
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.895 0.104
I85.9 Oesophageal varices without bleeding
0.000 0.896 0.104
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.896 0.104
I51.6 Cardiovascular disease, unspecified
0.000 0.899 0.101
I49 Other cardiac arrhythmias
0.000 0.900 0.100
I09.8 Other specified rheumatic heart diseases
0.001 0.901 0.099
I09.2 Chronic rheumatic pericarditis
0.001 0.901 0.099
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.001 0.901 0.099
I09.0 Rheumatic myocarditis
0.001 0.901 0.099
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.901 0.099
I86.8 Varicose veins of other specified sites
0.000 0.901 0.099
I51.5 Myocardial degeneration
0.000 0.901 0.098
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.901 0.098
I09.9 Rheumatic heart disease, unspecified
0.001 0.904 0.095
I05.0 Mitral stenosis
0.000 0.905 0.094
I49.0 Ventricular fibrillation and flutter
0.000 0.906 0.094
I45.1 Other and unspecified right bundle-branch block
0.000 0.906 0.094
I44.1 Atrioventricular block, second degree
0.002 0.907 0.091
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.907 0.093
I51.0 Cardiac septal defect, acquired
0.000 0.908 0.091
I47.1 Supraventricular tachycardia
0.000 0.909 0.091
I86.2 Pelvic varices
0.000 0.909 0.091
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.910 0.090
I06.8 Other rheumatic aortic valve diseases
0.001 0.910 0.090
I06.2 Rheumatic aortic stenosis with insufficiency
0.001 0.910 0.090
I06.1 Rheumatic aortic insufficiency
0.001 0.910 0.090
I51.9 Heart disease, unspecified
0.000 0.913 0.087
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.913 0.087
I07.9 Tricuspid valve disease, unspecified
0.000 0.914 0.085
I07.8 Other tricuspid valve diseases
0.000 0.914 0.085
I07.2 Tricuspid stenosis with insufficiency
0.000 0.914 0.085
I07.0 Tricuspid stenosis
0.000 0.914 0.085
I87.8 Other specified disorders of veins
0.000 0.915 0.085
I86.0 Sublingual varices
0.000 0.915 0.085
I67.2 Cerebral atherosclerosis
0.000 0.915 0.085
I86.4 Gastric varices
0.000 0.916 0.084
I88.8 Other nonspecific lymphadenitis
0.000 0.916 0.084
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.916 0.084
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.917 0.083
I67.5 Moyamoya disease
0.000 0.917 0.083
I67.4 Hypertensive encephalopathy
0.000 0.917 0.083
I67.3 Progressive vascular leukoencephalopathy
0.000 0.917 0.083
I51.4 Myocarditis, unspecified
0.000 0.917 0.083
I60 Subarachnoid haemorrhage
0.001 0.919 0.081
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.920 0.079
I05.8 Other mitral valve diseases
0.000 0.921 0.078
I27 Other pulmonary heart diseases
0.000 0.924 0.076
I35.0 Aortic (valve) stenosis
0.000 0.925 0.075
I06.0 Rheumatic aortic stenosis
0.001 0.926 0.073
I86.3 Vulval varices
0.000 0.926 0.074
I20.1 Angina pectoris with documented spasm
0.001 0.927 0.072
I49.2 Junctional premature depolarisation
0.000 0.928 0.072
I67.8 Other specified cerebrovascular diseases
0.000 0.929 0.071
I05.2 Mitral stenosis with insufficiency
0.000 0.930 0.070
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.931 0.068
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.932 0.068
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.934 0.066
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.936 0.064
I49.4 Other and unspecified premature depolarisation
0.000 0.936 0.064
I87.1 Compression of vein
0.000 0.936 0.063
I07.1 Tricuspid insufficiency
0.000 0.937 0.063
I05.1 Rheumatic mitral insufficiency
0.001 0.937 0.063
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.940 0.059
I60.5 Subarachnoid haemorrhage from vertebral artery
0.001 0.941 0.058
I35.9 Aortic valve disorder, unspecified
0.000 0.942 0.058
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.944 0.056
I21.4 Acute subendocardial myocardial infarction
0.001 0.944 0.055
I88.9 Nonspecific lymphadenitis, unspecified
0.001 0.944 0.055
I51.8 Other ill-defined heart diseases
0.000 0.945 0.055
I27.1 Kyphoscoliotic heart disease
0.000 0.945 0.055
I60.8 Other subarachnoid haemorrhage
0.000 0.946 0.054
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.001 0.946 0.054
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.001 0.947 0.052
I67.1 Cerebral aneurysm, nonruptured
0.000 0.948 0.052
I49.1 Atrial premature depolarisation
0.000 0.949 0.051
I60.4 Subarachnoid haemorrhage from basilar artery
0.001 0.949 0.050
I27.8 Other specified pulmonary heart diseases
0.000 0.950 0.049
E78.5 Hyperlipidaemia, unspecified
0.000 0.950 0.050
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.951 0.049
N81.4 Uterovaginal prolapse, unspecified
0.048 0.952 0.000
I34.1 Mitral (valve) prolapse
0.000 0.952 0.047
I49.5 Sick sinus syndrome
0.000 0.953 0.047
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.001 0.954 0.045
I35.1 Aortic (valve) insufficiency
0.000 0.954 0.046
I27.0 Primary pulmonary hypertension
0.000 0.957 0.043
I77.6 Arteritis, unspecified
0.019 0.957 0.024
I05.9 Mitral valve disease, unspecified
0.001 0.957 0.042
I35.8 Other aortic valve disorders
0.001 0.960 0.040
I27.2 Other secondary pulmonary hypertension
0.000 0.960 0.040
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.961 0.039
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.965 0.035
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.967 0.033
I51.7 Cardiomegaly
0.000 0.967 0.033
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.968 0.032
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.001 0.969 0.030
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.972 0.028
Z95.1 Presence of aortocoronary bypass graft
0.000 0.973 0.027
I89.1 Lymphangitis
0.000 0.973 0.026
Z95.3 Presence of xenogenic heart valve
0.000 0.974 0.026
I49.3 Ventricular premature depolarisation
0.000 0.976 0.024
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.001 0.976 0.023
I27.9 Pulmonary heart disease, unspecified
0.001 0.977 0.023
Z95.4 Presence of other heart-valve replacement
0.000 0.979 0.021
Z95.2 Presence of prosthetic heart valve
0.000 0.981 0.019
Z95.0 Presence of cardiac pacemaker
0.000 0.981 0.019
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.001 0.982 0.017
I49.9 Cardiac arrhythmia, unspecified
0.000 0.982 0.018
I86.1 Scrotal varices
0.002 0.983 0.016
I67.9 Cerebrovascular disease, unspecified
0.000 0.983 0.017
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.015 0.985 0.000
I95.9 Hypotension, unspecified
0.000 0.985 0.015
I89.0 Lymphoedema, not elsewhere classified
0.000 0.986 0.014
F22 Persistent delusional disorders
0.014 0.986 0.000
I49.8 Other specified cardiac arrhythmias
0.001 0.986 0.013
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.001 0.986 0.013
I34.0 Mitral (valve) insufficiency
0.000 0.986 0.014
F29 Unspecified nonorganic psychosis
0.014 0.986 0.000
F22.0 Delusional disorder
0.013 0.987 0.000
F25 Schizoaffective disorders
0.013 0.987 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.001 0.987 0.012
F22.9 Persistent delusional disorder, unspecified
0.012 0.988 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.012 0.988 0.000
F20 Schizophrenia
0.012 0.988 0.000
F21 Schizotypal disorder
0.012 0.988 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.000 0.988 0.012
F23 Acute and transient psychotic disorders
0.012 0.988 0.000
F20.0 Paranoid schizophrenia
0.011 0.989 0.000
F25.9 Schizoaffective disorder, unspecified
0.011 0.989 0.000
F25.2 Schizoaffective disorder, mixed type
0.011 0.989 0.000
F28 Other nonorganic psychotic disorders
0.011 0.989 0.000
F24 Induced delusional disorder
0.011 0.989 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.989 0.011
F22.8 Other persistent delusional disorders
0.010 0.990 0.000
R60.0 Localised oedema
0.000 0.990 0.010
C44.2 Skin of ear and external auricular canal
0.010 0.990 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.010 0.990 0.000
F25.1 Schizoaffective disorder, depressive type
0.010 0.990 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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