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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7221595
log Bayes Factor = 2.98123
Chromosome 17   position 4,007,594  (GRCh37) Explore rs7221595 on Ensembl!
Variant rs7221595 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.990 0.010 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
E11.3 With ophthalmic complications
0.907 0.093 0.000
E11.5 With peripheral circulatory complications
0.884 0.116 0.000
E11.4 With neurological complications
0.825 0.175 0.000
E11.2 With renal complications
0.813 0.187 0.000
E11.1 With ketoacidosis
0.701 0.299 0.000
E11.8 With unspecified complications
0.699 0.300 0.000
I10 Essential (primary) hypertension
0.695 0.305 0.000
E11.7 With multiple complications
0.694 0.306 0.000
E11.0 With coma
0.684 0.316 0.000
E11.6 With other specified complications
0.548 0.451 0.000
H65-H75 Diseases of middle ear and mastoid
0.487 0.513 0.000
H72 Perforation of tympanic membrane
0.483 0.517 0.000
H72.0 Central perforation of tympanic membrane
0.478 0.522 0.000
H66 Suppurative and unspecified otitis media
0.477 0.523 0.000
H71 Cholesteatoma of middle ear
0.475 0.525 0.000
E10-E14 Diabetes mellitus
0.458 0.542 0.000
H74 Other disorders of middle ear and mastoid
0.451 0.549 0.000
H66.9 Otitis media, unspecified
0.437 0.563 0.000
H66.0 Acute suppurative otitis media
0.432 0.568 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.422 0.578 0.000
E14 Unspecified diabetes mellitus
0.416 0.584 0.000
H69 Other disorders of Eustachian tube
0.411 0.589 0.000
H74.0 Tympanosclerosis
0.406 0.594 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.405 0.595 0.000
H74.1 Adhesive middle ear disease
0.386 0.614 0.000
H72.1 Attic perforation of tympanic membrane
0.382 0.618 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.372 0.628 0.000
H72.2 Other marginal perforations of tympanic membrane
0.367 0.633 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.365 0.635 0.000
H72.8 Other perforations of tympanic membrane
0.365 0.635 0.000
H69.8 Other specified disorders of Eustachian tube
0.363 0.637 0.000
H66.4 Suppurative otitis media, unspecified
0.362 0.638 0.000
H66.3 Other chronic suppurative otitis media
0.360 0.640 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.357 0.643 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.351 0.649 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.351 0.649 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.350 0.650 0.000
H68 Eustachian salpingitis and obstruction
0.350 0.650 0.000
H67 Otitis media in diseases classified elsewhere
0.350 0.650 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.346 0.654 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.345 0.655 0.000
E14.2 Withrenal complications
0.342 0.658 0.000
H73 Other disorders of tympanic membrane
0.340 0.660 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.338 0.662 0.000
E14.3 With ophthalmic complications
0.337 0.663 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.337 0.663 0.000
H70 Mastoiditis and related conditions
0.330 0.669 0.000
E12 Malnutrition-related diabetes mellitus
0.328 0.672 0.000
E14.5 With peripheral circulatory complications
0.325 0.675 0.000
I10-I15 Hypertensive diseases
0.315 0.685 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.314 0.686 0.000
E14.4 With neurological complications
0.314 0.686 0.000
E14.6 With other specified complications
0.309 0.690 0.000
E13 Other specified diabetes mellitus
0.307 0.693 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.302 0.698 0.000
E14.9 Without complications
0.301 0.699 0.000
E14.8 With unspecified complications
0.298 0.701 0.000
E14.7 With multiple complications
0.298 0.701 0.000
E14.1 With ketoacidosis
0.298 0.701 0.000
E14.0 With coma
0.298 0.701 0.000
H69.0 Patulous Eustachian tube
0.295 0.705 0.000
T83.2 Mechanical complication of graft of urinary organ
0.290 0.710 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.287 0.713 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.287 0.713 0.000
H69.9 Eustachian tube disorder, unspecified
0.281 0.719 0.000
H74.4 Polyp of middle ear
0.266 0.733 0.000
I15 Secondary hypertension
0.265 0.735 0.000
H67.8 Otitis media in other diseases classified elsewhere
0.251 0.749 0.000
H67.1 Otitis media in viral diseases classified elsewhere
0.251 0.749 0.000
H67.0 Otitis media in bacterial diseases classified elsewhere
0.251 0.749 0.000
H68.1 Obstruction of Eustachian tube
0.251 0.749 0.000
H68.0 Eustachian salpingitis
0.251 0.749 0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.251 0.749 0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.251 0.749 0.000
H70.8 Other mastoiditis and related conditions
0.250 0.750 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.244 0.756 0.000
H73.1 Chronic myringitis
0.244 0.756 0.000
H73.0 Acute myringitis
0.244 0.756 0.000
H70.1 Chronic mastoiditis
0.243 0.757 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.242 0.758 0.000
H70.2 Petrositis
0.237 0.763 0.000
H70.0 Acute mastoiditis
0.237 0.763 0.000
E12.9 Without complications
0.235 0.764 0.000
E12.8 With unspecified complications
0.235 0.764 0.000
E12.7 With multiple complications
0.235 0.764 0.000
E12.6 With other specified complications
0.235 0.764 0.000
E12.5 With peripheral circulatory complications
0.235 0.764 0.000
E12.4 With neurological complications
0.235 0.764 0.000
E12.3 With ophthalmic complications
0.235 0.764 0.000
E12.2 With renal complications
0.235 0.764 0.000
E12.1 With ketoacidosis
0.235 0.764 0.000
E12.0 With coma
0.235 0.764 0.000
I11 Hypertensive heart disease
0.235 0.765 0.000
H73.8 Other specified disorders of tympanic membrane
0.234 0.766 0.000
I13 Hypertensive heart and renal disease
0.226 0.774 0.000
I15.1 Hypertension secondary to other renal disorders
0.223 0.777 0.000
E13.8 With unspecified complications
0.220 0.780 0.000
E13.7 With multiple complications
0.220 0.780 0.000
E13.6 With other specified complications
0.220 0.780 0.000
E13.5 With peripheral circulatory complications
0.220 0.780 0.000
E13.4 With neurological complications
0.220 0.780 0.000
E13.3 With ophthalmic complications
0.220 0.780 0.000
E13.2 With renal complications
0.220 0.780 0.000
E13.1 With ketoacidosis
0.220 0.780 0.000
E13.0 With coma
0.220 0.780 0.000
I15.9 Seconday hypertension, unspecified
0.201 0.799 0.000
E13.9 Without complications
0.199 0.801 0.000
H70.9 Mastoiditis, unspecified
0.190 0.809 0.000
I15.8 Other secondary hypertension
0.190 0.810 0.000
I15.2 Hypertension secondary to endocrine disorders
0.190 0.810 0.000
I15.0 Renovascular hypertension
0.190 0.810 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.181 0.819 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.165 0.835 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.162 0.838 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.162 0.838 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.162 0.838 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.162 0.838 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.142 0.858 0.000
E10 Insulin-dependent diabetes mellitus
0.135 0.865 0.000
I08 Multiple valve diseases
0.135 0.865 0.000
I05-I09 Chronic rheumatic heart diseases
0.129 0.871 0.000
Chapter VIII Diseases of the ear and mastoid process
0.128 0.872 0.000
I05 Rheumatic mitral valve diseases
0.121 0.879 0.000
H65 Nonsuppurative otitis media
0.120 0.880 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.119 0.881 0.000
H60-H62 Diseases of external ear
0.117 0.883 0.000
I05.2 Mitral stenosis with insufficiency
0.115 0.885 0.000
H61 Other disorders of external ear
0.108 0.892 0.000
E10.5 With peripheral circulatory complications
0.107 0.893 0.000
E10.8 With unspecified complications
0.105 0.895 0.000
I09 Other rheumatic heart diseases
0.104 0.896 0.000
Chapter IX Diseases of the circulatory system
0.101 0.899 0.000
I06 Rheumatic aortic valve diseases
0.099 0.901 0.000
E10.7 With multiple complications
0.097 0.903 0.000
I05.1 Rheumatic mitral insufficiency
0.097 0.903 0.000
I08.8 Other multiple valve diseases
0.097 0.903 0.000
I08.9 Multiple valve disease, unspecified
0.097 0.903 0.000
E10.2 With renal complications
0.092 0.907 0.000
H61.2 Impacted cerumen
0.091 0.909 0.000
H65.1 Other acute nonsuppurative otitis media
0.091 0.909 0.000
I05.9 Mitral valve disease, unspecified
0.091 0.909 0.000
H61.9 Disorder of external ear, unspecified
0.091 0.909 0.000
I12 Hypertensive renal disease
0.089 0.911 0.000
E10.4 With neurological complications
0.087 0.913 0.000
I05.8 Other mitral valve diseases
0.087 0.913 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.087 0.913 0.000
H61.8 Other specified disorders of external ear
0.087 0.913 0.000
H65.0 Acute serous otitis media
0.086 0.914 0.000
I09.9 Rheumatic heart disease, unspecified
0.086 0.914 0.000
E10.9 Without complications
0.083 0.917 0.000
H60 Otitis externa
0.083 0.917 0.000
E10.6 With other specified complications
0.082 0.917 0.000
E10.3 With ophthalmic complications
0.082 0.918 0.000
H61.1 Non-infective disorders of pinna
0.081 0.919 0.000
I07 Rheumatic tricuspid valve diseases
0.080 0.920 0.000
H61.0 Perichondritis of external ear
0.080 0.920 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.079 0.921 0.000
I06.0 Rheumatic aortic stenosis
0.078 0.922 0.000
I08.0 Disorders of both mitral and aortic valves
0.077 0.923 0.000
E10.1 With ketoacidosis
0.076 0.924 0.000
I09.8 Other specified rheumatic heart diseases
0.074 0.925 0.000
I09.2 Chronic rheumatic pericarditis
0.074 0.925 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.074 0.925 0.000
I09.0 Rheumatic myocarditis
0.074 0.925 0.000
H65.4 Other chronic nonsuppurative otitis media
0.074 0.926 0.000
H61.3 Acquired stenosis of external ear canal
0.074 0.926 0.000
H65.2 Chronic serous otitis media
0.074 0.926 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.073 0.927 0.000
I00-I02 Acute rheumatic fever
0.072 0.928 0.000
I05.0 Mitral stenosis
0.072 0.928 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.071 0.928 0.000
I06.8 Other rheumatic aortic valve diseases
0.071 0.928 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.071 0.928 0.000
I06.1 Rheumatic aortic insufficiency
0.071 0.928 0.000
E10.0 With coma
0.069 0.931 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.068 0.932 0.000
H60.0 Abscess of external ear
0.066 0.934 0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere
0.065 0.935 0.000
E20-E35 Disorders of other endocrine glands
0.065 0.935 0.000
I27 Other pulmonary heart diseases
0.064 0.936 0.000
H62.8 Other disorders of external ear in diseases classified elsewhere
0.062 0.937 0.000
H62.4 Otitis externa in other diseases classified elsewhere
0.062 0.937 0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere
0.062 0.937 0.000
H62.2 Otitis externa in mycoses
0.062 0.937 0.000
H62.1 Otitis externa in viral diseases classified elsewhere
0.062 0.937 0.000
H60.9 Otitis externa, unspecified
0.062 0.938 0.000
H60.5 Acute otitis externa, non-infective
0.061 0.939 0.000
I27.0 Primary pulmonary hypertension
0.061 0.939 0.000
E29 Testicular dysfunction
0.061 0.939 0.000
H60.3 Other infective otitis externa
0.060 0.940 0.000
H60.2 Malignant otitis externa
0.059 0.941 0.000
H80-H83 Diseases of inner ear
0.059 0.941 0.000
E27 Other disorders of adrenal gland
0.059 0.941 0.000
E29.1 Testicular hypofunction
0.058 0.942 0.000
I07.9 Tricuspid valve disease, unspecified
0.057 0.942 0.000
I07.8 Other tricuspid valve diseases
0.057 0.942 0.000
I07.2 Tricuspid stenosis with insufficiency
0.057 0.942 0.000
I07.0 Tricuspid stenosis
0.057 0.942 0.000
H60.8 Other otitis externa
0.055 0.945 0.000
E40-E46 Malnutrition
0.054 0.946 0.000
E27.1 Primary adrenocortical insufficiency
0.054 0.946 0.000
H60.4 Cholesteatoma of external ear
0.053 0.947 0.000
H60.1 Cellulitis of external ear
0.053 0.947 0.000
I28 Other diseases of pulmonary vessels
0.053 0.947 0.000
E20 Hypoparathyroidism
0.053 0.947 0.000
I02 Rheumatic chorea
0.052 0.948 0.000
I01 Rheumatic fever with heart involvement
0.052 0.948 0.000
I00 Rheumatic fever without mention of heart involvement
0.052 0.948 0.000
E31 Polyglandular dysfunction
0.051 0.949 0.000
I50.0 Congestive heart failure
0.051 0.949 0.000
I20-I25 Ischaemic heart diseases
0.051 0.949 0.000
I30-I52 Other forms of heart disease
0.049 0.951 0.000
E25 Adrenogenital disorders
0.048 0.951 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.048 0.952 0.000
E24 Cushing's syndrome
0.048 0.952 0.000
E26 Hyperaldosteronism
0.048 0.952 0.000
H65.3 Chronic mucoid otitis media
0.048 0.952 0.000
E27.2 Addisonian crisis
0.047 0.953 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.047 0.953 0.000
E32 Diseases of thymus
0.047 0.953 0.000
E30 Disorders of puberty, not elsewhere classified
0.047 0.953 0.000
I27.9 Pulmonary heart disease, unspecified
0.046 0.954 0.000
E22 Hyperfunction of pituitary gland
0.046 0.954 0.000
I27.1 Kyphoscoliotic heart disease
0.046 0.954 0.000
E23 Hypofunction and other disorders of pituitary gland
0.046 0.954 0.000
I44 Atrioventricular and left bundle-branch block
0.046 0.954 0.000
I50 Heart failure
0.046 0.954 0.000
I07.1 Tricuspid insufficiency
0.045 0.955 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.045 0.955 0.000
I36 Nonrheumatic tricuspid valve disorders
0.045 0.955 0.000
E20.9 Hypoparathyroidism, unspecified
0.045 0.955 0.000
E46 Unspecified protein-energy malnutrition
0.045 0.955 0.000
H81 Disorders of vestibular function
0.044 0.955 0.000
I44.7 Left bundle-branch block, unspecified
0.044 0.956 0.000
E29.9 Testicular dysfunction, unspecified
0.044 0.956 0.000
E29.8 Other testicular dysfunction
0.044 0.956 0.000
E29.0 Testicular hyperfunction
0.044 0.956 0.000
I42 Cardiomyopathy
0.043 0.957 0.000
I27.2 Other secondary pulmonary hypertension
0.043 0.957 0.000
I42.0 Dilated cardiomyopathy
0.043 0.957 0.000
I30 Acute pericarditis
0.043 0.957 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.043 0.957 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.043 0.957 0.000
E27.5 Adrenomedullary hyperfunction
0.042 0.958 0.000
E27.0 Other adrenocortical overactivity
0.042 0.958 0.000
I22 Subsequent myocardial infarction
0.042 0.958 0.000
I24 Other acute ischaemic heart diseases
0.042 0.958 0.000
E31.0 Autoimmune polyglandular failure
0.041 0.959 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.041 0.959 0.000
E27.8 Other specified disorders of adrenal gland
0.041 0.959 0.000
I12.9 Hypertensive renal disease without renal failure
0.041 0.959 0.000
H81.0 Meniere's disease
0.041 0.959 0.000
E50-E64 Other nutritional deficiencies
0.041 0.959 0.000
E28 Ovarian dysfunction
0.041 0.959 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.040 0.960 0.000
I44.1 Atrioventricular block, second degree
0.040 0.960 0.000
I28.8 Other specified diseases of pulmonary vessels
0.039 0.960 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.039 0.961 0.000
E45 Retarded development following protein-energy malnutrition
0.039 0.961 0.000
E43 Unspecified severe protein-energy malnutrition
0.039 0.961 0.000
E42 Marasmic kwashiorkor
0.039 0.961 0.000
E41 Nutritional marasmus
0.039 0.961 0.000
E40 Kwashiorkor
0.039 0.961 0.000
I44.3 Other and unspecified atrioventricular block
0.039 0.961 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.038 0.961 0.000
I28.1 Aneurysm of pulmonary artery
0.038 0.961 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.038 0.961 0.000
E20.8 Other hypoparathyroidism
0.038 0.962 0.000
E20.1 Pseudohypoparathyroidism
0.038 0.962 0.000
E20.0 Idiopathic hypoparathyroidism
0.038 0.962 0.000
E27.9 Disorder of adrenal gland, unspecified
0.038 0.962 0.000
E34 Other endocrine disorders
0.038 0.962 0.000
I27.8 Other specified pulmonary heart diseases
0.038 0.962 0.000
I25 Chronic ischaemic heart disease
0.038 0.962 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.037 0.962 0.000
I01.8 Other acute rheumatic heart disease
0.037 0.962 0.000
I01.2 Acute rheumatic myocarditis
0.037 0.962 0.000
I01.1 Acute rheumatic endocarditis
0.037 0.962 0.000
I01.0 Acute rheumatic pericarditis
0.037 0.962 0.000
I02.9 Rheumatic chorea without heart involvement
0.037 0.962 0.000
I02.0 Rheumatic chorea with heart involvement
0.037 0.962 0.000
I44.6 Other and unspecified fascicular block
0.038 0.962 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.037 0.963 0.000
I37 Pulmonary valve disorders
0.037 0.963 0.000
E23.6 Other disorders of pituitary gland
0.037 0.963 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.037 0.963 0.000
I30.1 Infective pericarditis
0.037 0.963 0.000
E31.9 Polyglandular dysfunction, unspecified
0.037 0.963 0.000
E31.8 Other polyglandular dysfunction
0.037 0.963 0.000
E31.1 Polyglandular hyperfunction
0.037 0.963 0.000
I51 Complications and ill-defined descriptions of heart disease
0.037 0.963 0.000
I40 Acute myocarditis
0.037 0.963 0.000
E24.2 Drug-induced Cushing's syndrome
0.037 0.963 0.000
E23.7 Disorder of pituitary gland, unspecified
0.036 0.964 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.036 0.964 0.000
E26.0 Primary hyperaldosteronism
0.036 0.964 0.000
E22.1 Hyperprolactinaemia
0.036 0.964 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.036 0.964 0.000
I24.8 Other forms of acute ischaemic heart disease
0.036 0.964 0.000
I52 Other heart disorders in diseases classified elsewhere
0.035 0.965 0.000
I48 Atrial fibrillation and flutter
0.035 0.965 0.000
I41 Myocarditis in diseases classified elsewhere
0.035 0.965 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.035 0.965 0.000
I32 Pericarditis in diseases classified elsewhere
0.035 0.965 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.035 0.965 0.000
E24.9 Cushing's syndrome, unspecified
0.035 0.965 0.000
E25.9 Adrenogenital disorder, unspecified
0.035 0.965 0.000
E25.8 Other adrenogenital disorders
0.035 0.965 0.000
E15 Nondiabetic hypoglycaemic coma
0.035 0.965 0.000
E24.8 Other Cushing's syndrome
0.035 0.965 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.035 0.965 0.000
E24.3 Ectopic ACTH syndrome
0.035 0.965 0.000
E24.1 Nelson's syndrome
0.035 0.965 0.000
I30.9 Acute pericarditis, unspecified
0.035 0.965 0.000
E26.9 Hyperaldosteronism, unspecified
0.034 0.965 0.000
E26.8 Other hyperaldosteronism
0.034 0.965 0.000
E26.1 Secondary hyperaldosteronism
0.034 0.965 0.000
I42.4 Endocardial fibroelastosis
0.035 0.965 0.000
E16 Other disorders of pancreatic internal secretion
0.034 0.966 0.000
H81.3 Other peripheral vertigo
0.034 0.966 0.000
E30.9 Disorder of puberty, unspecified
0.033 0.966 0.000
E30.8 Other disorders of puberty
0.033 0.966 0.000
E30.1 Precocious puberty
0.033 0.966 0.000
E30.0 Delayed puberty
0.033 0.966 0.000
E32.9 Disease of thymus, unspecified
0.033 0.966 0.000
E32.8 Other diseases of thymus
0.033 0.966 0.000
E32.1 Abscess of thymus
0.033 0.966 0.000
E32.0 Persistent hyperplasia of thymus
0.033 0.966 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.033 0.966 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.033 0.966 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.033 0.966 0.000
E55 Vitamin D deficiency
0.034 0.966 0.000
E24.0 Pituitary-dependent Cushing's disease
0.033 0.966 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.033 0.966 0.000
E22.8 Other hyperfunction of pituitary gland
0.033 0.966 0.000
I51.9 Heart disease, unspecified
0.033 0.966 0.000
I33 Acute and subacute endocarditis
0.033 0.967 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.033 0.967 0.000
E23.1 Drug-induced hypopituitarism
0.033 0.967 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.033 0.967 0.000
I44.5 Left posterior fascicular block
0.033 0.967 0.000
E23.2 Diabetes insipidus
0.033 0.967 0.000
I51.7 Cardiomegaly
0.033 0.967 0.000
I23 Certain current complications following acute myocardial infarction
0.033 0.967 0.000
I44.4 Left anterior fascicular block
0.033 0.967 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.033 0.967 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.033 0.967 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.032 0.967 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.032 0.967 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.032 0.967 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.032 0.967 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.032 0.968 0.000
H80 Otosclerosis
0.032 0.968 0.000
H81.4 Vertigo of central origin
0.032 0.968 0.000
E28.3 Primary ovarian failure
0.032 0.968 0.000
H81.8 Other disorders of vestibular function
0.031 0.968 0.000
E22.0 Acromegaly and pituitary gigantism
0.031 0.968 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.031 0.969 0.000
I42.5 Other restrictive cardiomyopathy
0.031 0.969 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.031 0.969 0.000
I60-I69 Cerebrovascular diseases
0.031 0.969 0.000
I30.8 Other forms of acute pericarditis
0.031 0.969 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.031 0.969 0.000
H81.9 Disorder of vestibular function, unspecified
0.031 0.969 0.000
E65-E68 Obesity and other hyperalimentation
0.030 0.969 0.000
I25.3 Aneurysm of heart
0.030 0.970 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.029 0.970 0.000
E63 Other nutritional deficiencies
0.029 0.970 0.000
E56 Other vitamin deficiencies
0.029 0.970 0.000
E51 Thiamine deficiency
0.029 0.970 0.000
E50 Vitamin A deficiency
0.029 0.970 0.000
E60 Dietary zinc deficiency
0.029 0.970 0.000
E59 Dietary selenium deficiency
0.029 0.970 0.000
E58 Dietary calcium deficiency
0.029 0.970 0.000
E54 Ascorbic acid deficiency
0.029 0.970 0.000
E52 Niacin deficiency [pellagra]
0.029 0.970 0.000
E28.9 Ovarian dysfunction, unspecified
0.029 0.971 0.000
E28.8 Other ovarian dysfunction
0.029 0.971 0.000
E28.1 Androgen excess
0.029 0.971 0.000
E28.0 Oestrogen excess
0.029 0.971 0.000
E34.8 Other specified endocrine disorders
0.029 0.971 0.000
I61 Intracerebral haemorrhage
0.029 0.971 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.029 0.971 0.000
I22.8 Subsequent myocardial infarction of other sites
0.029 0.971 0.000
I37.1 Pulmonary valve insufficiency
0.029 0.971 0.000
E55.9 Vitamin D deficiency, unspecified
0.028 0.971 0.000
I24.1 Dressler's syndrome
0.028 0.971 0.000
E44.1 Mild protein-energy malnutrition
0.028 0.972 0.000
E44.0 Moderate protein-energy malnutrition
0.028 0.972 0.000
I38 Endocarditis, valve unspecified
0.028 0.972 0.000
I40.0 Infective myocarditis
0.028 0.972 0.000
E16.2 Hypoglycaemia, unspecified
0.028 0.972 0.000
E34.5 Androgen resistance syndrome
0.027 0.972 0.000
E34.4 Constitutional tall stature
0.027 0.972 0.000
E34.3 Short stature, not elsewhere classified
0.027 0.972 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.027 0.972 0.000
E34.1 Other hypersecretion of intestinal hormones
0.027 0.972 0.000
I25.6 Silent myocardial ischaemia
0.027 0.973 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.027 0.973 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.027 0.973 0.000
I37.9 Pulmonary valve disorder, unspecified
0.027 0.973 0.000
I37.8 Other pulmonary valve disorders
0.027 0.973 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.027 0.973 0.000
I37.0 Pulmonary valve stenosis
0.027 0.973 0.000
I42.8 Other cardiomyopathies
0.027 0.973 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.027 0.973 0.000
I51.5 Myocardial degeneration
0.027 0.973 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.027 0.973 0.000
H81.1 Benign paroxysmal vertigo
0.027 0.973 0.000
I40.9 Acute myocarditis, unspecified
0.026 0.973 0.000
I40.8 Other acute myocarditis
0.026 0.973 0.000
I40.1 Isolated myocarditis
0.026 0.973 0.000
I51.6 Cardiovascular disease, unspecified
0.027 0.973 0.000
I42.9 Cardiomyopathy, unspecified
0.026 0.974 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.026 0.974 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.026 0.974 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.026 0.974 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.026 0.974 0.000
I25.5 Ischaemic cardiomyopathy
0.026 0.974 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.025 0.974 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.025 0.974 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.025 0.974 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.025 0.974 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.025 0.974 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.025 0.974 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.025 0.974 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.025 0.974 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.025 0.974 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.025 0.974 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.025 0.974 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.025 0.974 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.025 0.974 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.025 0.974 0.000
I48.4 Atypical atrial flutter
0.025 0.974 0.000
I48.3 Typical atrial flutter
0.025 0.974 0.000
I48.2 Chronic atrial fibrillation
0.025 0.974 0.000
I48.1 Persistent atrial fibrillation
0.025 0.974 0.000
I48.0 Paroxysmal atrial fibrillation
0.025 0.974 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.025 0.974 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.025 0.974 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.025 0.974 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.026 0.974 0.000
I42.6 Alcoholic cardiomyopathy
0.025 0.975 0.000
H83 Other diseases of inner ear
0.025 0.975 0.000
I25.4 Coronary artery aneurysm
0.025 0.975 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.025 0.975 0.000
I62 Other nontraumatic intracranial haemorrhage
0.025 0.975 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.025 0.975 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.025 0.975 0.000
E16.4 Abnormal secretion of gastrin
0.025 0.975 0.000
E16.3 Increased secretion of glucagon
0.025 0.975 0.000
I20 Angina pectoris
0.025 0.975 0.000
E55.0 Rickets, active
0.024 0.976 0.000
I33.9 Acute endocarditis, unspecified
0.024 0.976 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.024 0.976 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.024 0.976 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.024 0.976 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.024 0.976 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.024 0.976 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.024 0.976 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.024 0.976 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.024 0.976 0.000
E61 Deficiency of other nutrient elements
0.024 0.976 0.000
E34.0 Carcinoid syndrome
0.023 0.976 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.024 0.976 0.000
H80.8 Other otosclerosis
0.023 0.977 0.000
H80.2 Cochlear otosclerosis
0.023 0.977 0.000
H80.1 Otosclerosis involving oval window, obliterative
0.023 0.977 0.000
H80.0 Otosclerosis involving oval window, nonobliterative
0.023 0.977 0.000
I26 Pulmonary embolism
0.023 0.977 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.023 0.977 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.023 0.977 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.023 0.977 0.000
E34.9 Endocrine disorder, unspecified
0.022 0.978 0.000
I51.0 Cardiac septal defect, acquired
0.022 0.978 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.022 0.978 0.000
I20.1 Angina pectoris with documented spasm
0.022 0.978 0.000
E16.1 Other hypoglycaemia
0.022 0.978 0.000
I33.0 Acute and subacute infective endocarditis
0.022 0.978 0.000
I42.2 Other hypertrophic cardiomyopathy
0.022 0.978 0.000
E67 Other hyperalimentation
0.022 0.978 0.000
E68 Sequelae of hyperalimentation
0.022 0.978 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.022 0.978 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.022 0.978 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.022 0.978 0.000
I46 Cardiac arrest
0.022 0.978 0.000
I61.8 Other intracerebral haemorrhage
0.022 0.978 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.021 0.978 0.000
E50.9 Vitamin A deficiency, unspecified
0.021 0.979 0.000
E50.8 Other manifestations of vitamin A deficiency
0.021 0.979 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.021 0.979 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.021 0.979 0.000
E50.5 Vitamin A deficiency with night blindness
0.021 0.979 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.021 0.979 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.021 0.979 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.021 0.979 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.021 0.979 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.021 0.979 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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