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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72649272
log Bayes Factor = 12.7562
Chromosome 1   position 29,547,495  (GRCh37) Explore rs72649272 on Ensembl!
Variant rs72649272 is part of Cluster X0024

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
O63 Long labour
0.994 0.006 0.000
O63.1 Prolonged second stage (of labour)
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.991 0.009 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
H53-H54 Visual disturbances and blindness
0.982 0.018 0.000
Chapter XIV Diseases of the genitourinary system
0.975 0.025 0.000
J09-J18 Influenza and pneumonia
0.975 0.025 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.964 0.036 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.963 0.037 0.000
Chapter I Certain infectious and parasitic diseases
0.957 0.043 0.000
N17-N19 Renal failure
0.957 0.043 0.000
J18 Pneumonia, organism unspecified
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
I50 Heart failure
0.948 0.052 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.946 0.054 0.000
E70-E90 Metabolic disorders
0.943 0.057 0.000
L20-L30 Dermatitis and eczema
0.941 0.059 0.000
N30-N39 Other diseases of urinary system
0.939 0.061 0.000
I35 Nonrheumatic aortic valve disorders
0.935 0.065 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.932 0.068 0.000
H53 Visual disturbances
0.930 0.070 0.000
G90-G99 Other disorders of the nervous system
0.930 0.070 0.000
J18.9 Pneumonia, unspecified
0.927 0.073 0.000
N39 Other disorders of urinary system
0.924 0.076 0.000
J30-J39 Other diseases of upper respiratory tract
0.919 0.081 0.000
B95-B98 Bacterial, viral and other infectious agents
0.917 0.083 0.000
N39.3 Stress incontinence
0.916 0.084 0.000
I60-I69 Cerebrovascular diseases
0.916 0.084 0.000
H54 Blindness and low vision
0.916 0.084 0.000
N18 Chronic renal failure
0.915 0.085 0.000
I50.1 Left ventricular failure
0.914 0.086 0.000
H53.8 Other visual disturbances
0.913 0.087 0.000
I10-I15 Hypertensive diseases
0.913 0.087 0.000
H36 Retinal disorders in diseases classified elsewhere
0.911 0.089 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.909 0.091 0.000
N17 Acute renal failure
0.904 0.096 0.000
N25-N29 Other disorders of kidney and ureter
0.897 0.103 0.000
Chapter XX External causes of morbidity and mortality
0.890 0.110 0.000
H35 Other retinal disorders
0.890 0.110 0.000
I44 Atrioventricular and left bundle-branch block
0.883 0.117 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.880 0.120 0.000
L27 Dermatitis due to substances taken internally
0.877 0.123 0.000
J20-J22 Other acute lower respiratory infections
0.877 0.123 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
H55-H59 Other disorders of eye and adnexa
0.871 0.129 0.000
H10-H13 Disorders of conjunctiva
0.869 0.131 0.000
I35.0 Aortic (valve) stenosis
0.868 0.132 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.865 0.135 0.000
O00-O08 Pregnancy with abortive outcome
0.862 0.138 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.862 0.138 0.000
I46 Cardiac arrest
0.860 0.140 0.000
L82 Seborrhoeic keratosis
0.858 0.142 0.000
I12 Hypertensive renal disease
0.857 0.142 0.000
I71 Aortic aneurysm and dissection
0.856 0.144 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.855 0.145 0.000
H36.0 Diabetic retinopathy
0.855 0.145 0.000
N17.9 Acute renal failure, unspecified
0.852 0.148 0.000
O70 Perineal laceration during delivery
0.852 0.148 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.851 0.149 0.000
G91 Hydrocephalus
0.850 0.150 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.850 0.150 0.000
G93 Other disorders of brain
0.846 0.154 0.000
L89 Decubitus ulcer
0.844 0.156 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.842 0.158 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.842 0.158 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.842 0.158 0.000
H34 Retinal vascular occlusions
0.841 0.159 0.000
Chapter V Mental and behavioural disorders
0.841 0.159 0.000
E10-E14 Diabetes mellitus
0.838 0.162 0.000
J36 Peritonsillar abscess
0.833 0.167 0.000
H33 Retinal detachments and breaks
0.831 0.169 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.831 0.169 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.829 0.171 0.000
I73 Other peripheral vascular diseases
0.829 0.171 0.000
I51 Complications and ill-defined descriptions of heart disease
0.827 0.173 0.000
O16 Unspecified maternal hypertension
0.825 0.175 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.823 0.177 0.000
H54.7 Unspecified visual loss
0.821 0.179 0.000
O40 Polyhydramnios
0.821 0.179 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.815 0.185 0.000
E83 Disorders of mineral metabolism
0.813 0.187 0.000
N39.4 Other specified urinary incontinence
0.812 0.188 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.812 0.188 0.000
I60 Subarachnoid haemorrhage
0.811 0.189 0.000
J39 Other diseases of upper respiratory tract
0.809 0.191 0.000
N00-N08 Glomerular diseases
0.807 0.193 0.000
N18.9 Chronic renal failure, unspecified
0.805 0.195 0.000
J32 Chronic sinusitis
0.804 0.196 0.000
O30 Multiple gestation
0.802 0.198 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.801 0.199 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.799 0.201 0.000
J18.0 Bronchopneumonia, unspecified
0.799 0.201 0.000
I12.0 Hypertensive renal disease with renal failure
0.799 0.201 0.000
M15-M19 Arthrosis
0.799 0.201 0.000
L83 Acanthosis nigricans
0.794 0.206 0.000
B02 Zoster [herpes zoster]
0.794 0.206 0.000
N18.4 Chronic kidney disease, stage 4
0.794 0.206 0.000
I70 Atherosclerosis
0.793 0.207 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.793 0.207 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.793 0.207 0.000
O73 Retained placenta and membranes, without haemorrhage
0.792 0.208 0.000
L94 Other localised connective tissue disorders
0.790 0.209 0.000
O80-O84 Delivery
0.790 0.210 0.000
H31 Other disorders of choroid
0.789 0.211 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.789 0.211 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.788 0.212 0.000
J60-J70 Lung diseases due to external agents
0.787 0.213 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.787 0.213 0.000
M16 Coxarthrosis [arthrosis of hip]
0.787 0.213 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.786 0.214 0.000
Y84.8 Other medical procedures
0.786 0.214 0.000
G90 Disorders of autonomic nervous system
0.785 0.215 0.000
N18.5 Chronic kidney disease, stage 5
0.785 0.215 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.783 0.217 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.782 0.218 0.000
J22 Unspecified acute lower respiratory infection
0.782 0.218 0.000
M16.1 Other primary coxarthrosis
0.781 0.219 0.000
G91.9 Hydrocephalus, unspecified
0.779 0.221 0.000
H35.8 Other specified retinal disorders
0.778 0.222 0.000
I44.6 Other and unspecified fascicular block
0.777 0.223 0.000
H11 Other disorders of conjunctiva
0.776 0.224 0.000
E87.7 Fluid overload
0.776 0.224 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.773 0.227 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
I42 Cardiomyopathy
0.773 0.227 0.000
I73.9 Peripheral vascular disease, unspecified
0.770 0.230 0.000
N28.1 Cyst of kidney, acquired
0.768 0.232 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.767 0.233 0.000
E74 Other disorders of carbohydrate metabolism
0.767 0.233 0.000
O62 Abnormalities of forces of labour
0.766 0.234 0.000
I77 Other disorders of arteries and arterioles
0.766 0.234 0.000
O04 Medical abortion
0.765 0.235 0.000
O70.0 First degree perineal laceration during delivery
0.765 0.235 0.000
E20-E35 Disorders of other endocrine glands
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.764 0.236 0.000
I35.9 Aortic valve disorder, unspecified
0.764 0.236 0.000
O72 Postpartum haemorrhage
0.763 0.237 0.000
L40-L45 Papulosquamous disorders
0.762 0.238 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.762 0.238 0.000
I46.9 Cardiac arrest, unspecified
0.758 0.242 0.000
H54.0 Blindness, both eyes
0.757 0.243 0.000
J18.1 Lobar pneumonia, unspecified
0.757 0.243 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.755 0.245 0.000
F20 Schizophrenia
0.755 0.245 0.000
I62 Other nontraumatic intracranial haemorrhage
0.754 0.246 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.752 0.248 0.000
O47 False labour
0.751 0.249 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.750 0.250 0.000
E11 Non-insulin-dependent diabetes mellitus
0.749 0.251 0.000
O41 Other disorders of amniotic fluid and membranes
0.749 0.251 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.748 0.252 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.747 0.253 0.000
E50-E64 Other nutritional deficiencies
0.746 0.254 0.000
L81 Other disorders of pigmentation
0.742 0.258 0.000
J80 Adult respiratory distress syndrome
0.742 0.258 0.000
L29 Pruritus
0.742 0.258 0.000
O75.8 Other specified complications of labour and delivery
0.741 0.259 0.000
H35.9 Retinal disorder, unspecified
0.741 0.259 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.739 0.261 0.000
J14 Pneumonia due to Haemophilus influenzae
0.738 0.261 0.000
E87.0 Hyperosmolality and hypernatraemia
0.738 0.261 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.734 0.266 0.000
N99-N99 Other disorders of the genitourinary system
0.733 0.267 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.733 0.267 0.000
I44.0 Atrioventricular block, first degree
0.732 0.268 0.000
O48 Prolonged pregnancy
0.731 0.269 0.000
H57 Other disorders of eye and adnexa
0.730 0.270 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.730 0.270 0.000
O42 Premature rupture of membranes
0.730 0.270 0.000
L30 Other dermatitis
0.729 0.271 0.000
E83.5 Disorders of calcium metabolism
0.728 0.272 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.725 0.274 0.000
I51.9 Heart disease, unspecified
0.725 0.275 0.000
I44.7 Left bundle-branch block, unspecified
0.725 0.275 0.000
J33 Nasal polyp
0.725 0.275 0.000
E11.3 With ophthalmic complications
0.725 0.275 0.000
M45-M49 Spondylopathies
0.723 0.277 0.000
E40-E46 Malnutrition
0.723 0.277 0.000
G95 Other diseases of spinal cord
0.723 0.277 0.000
I50.0 Congestive heart failure
0.722 0.278 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.722 0.278 0.000
A80-A89 Viral infections of the central nervous system
0.721 0.279 0.000
I63 Cerebral infarction
0.720 0.280 0.000
O63.9 Long labour, unspecified
0.719 0.280 0.000
N30 Cystitis
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.283 0.000
O71 Other obstetric trauma
0.716 0.283 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.716 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.283 0.000
O61 Failed induction of labour
0.716 0.283 0.000
O60 Preterm delivery
0.716 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.716 0.284 0.000
J39.2 Other diseases of pharynx
0.714 0.286 0.000
I15 Secondary hypertension
0.714 0.286 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
O66 Other obstructed labour
0.713 0.287 0.000
N17.0 Acute renal failure with tubular necrosis
0.713 0.287 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.713 0.287 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.712 0.288 0.000
N18.0 End-stage renal disease
0.712 0.288 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.711 0.289 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.711 0.289 0.000
I72 Other aneurysm
0.711 0.289 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.290 0.000
H30 Chorioretinal inflammation
0.710 0.290 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.710 0.290 0.000
I71.0 Dissection of aorta [any part]
0.710 0.290 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.709 0.291 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.707 0.293 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.707 0.293 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.707 0.293 0.000
L93 Lupus erythematosus
0.707 0.293 0.000
L87 Transepidermal elimination disorders
0.707 0.293 0.000
L88 Pyoderma gangrenosum
0.707 0.293 0.000
L86 Keratoderma in diseases classified elsewhere
0.707 0.293 0.000
L80 Vitiligo
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
I30 Acute pericarditis
0.707 0.293 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.706 0.294 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.705 0.295 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.704 0.296 0.000
M80-M85 Disorders of bone density and structure
0.704 0.296 0.000
Chapter VIII Diseases of the ear and mastoid process
0.704 0.296 0.000
I35.8 Other aortic valve disorders
0.703 0.297 0.000
J10 Influenza due to identified influenza virus
0.702 0.298 0.000
J17 Pneumonia in diseases classified elsewhere
0.699 0.301 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.699 0.301 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.699 0.301 0.000
J12 Viral pneumonia, not elsewhere classified
0.699 0.301 0.000
J11 Influenza, virus not identified
0.699 0.301 0.000
J09 Influenza due to certain identified influenza virus
0.699 0.301 0.000
I50.9 Heart failure, unspecified
0.699 0.301 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.698 0.302 0.000
H11.9 Disorder of conjunctiva, unspecified
0.695 0.305 0.000
H33.0 Retinal detachment with retinal break
0.695 0.305 0.000
O63.0 Prolonged first stage (of labour)
0.694 0.306 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.694 0.306 0.000
O36 Maternal care for other known or suspected foetal problems
0.694 0.306 0.000
I12.9 Hypertensive renal disease without renal failure
0.694 0.306 0.000
G93.0 Cerebral cysts
0.693 0.307 0.000
J32.0 Chronic maxillary sinusitis
0.693 0.307 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.692 0.307 0.000
O45 Premature separation of placenta [abruptio placentae]
0.691 0.308 0.000
O44 Placenta praevia
0.691 0.308 0.000
O43 Placental disorders
0.691 0.308 0.000
O33 Maternal care for known or suspected disproportion
0.691 0.308 0.000
O31 Complications specific to multiple gestation
0.691 0.308 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.691 0.309 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.690 0.310 0.000
H54.9 Unspecified visual impairment (binocular)
0.690 0.310 0.000
I05-I09 Chronic rheumatic heart diseases
0.690 0.310 0.000
N10-N16 Renal tubulo-interstitial diseases
0.689 0.311 0.000
L50-L54 Urticaria and erythema
0.689 0.311 0.000
N18.2 Chronic kidney disease, stage 2
0.689 0.311 0.000
H34.8 Other retinal vascular occlusions
0.689 0.311 0.000
A30-A49 Other bacterial diseases
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.686 0.313 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.686 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.686 0.313 0.000
B65-B83 Helminthiases
0.686 0.313 0.000
B50-B64 Protozoal diseases
0.686 0.313 0.000
B15-B19 Viral hepatitis
0.686 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.686 0.313 0.000
A75-A79 Rickettsioses
0.686 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.686 0.313 0.000
A65-A69 Other spirochaetal diseases
0.686 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.686 0.313 0.000
A15-A19 Tuberculosis
0.686 0.313 0.000
O03 Spontaneous abortion
0.686 0.314 0.000
J18.8 Other pneumonia, organism unspecified
0.686 0.314 0.000
J18.2 Hypostatic pneumonia, unspecified
0.686 0.314 0.000
O30.0 Twin pregnancy
0.685 0.315 0.000
B02.9 Zoster without complication
0.685 0.315 0.000
G93.8 Other specified disorders of brain
0.684 0.316 0.000
H53.1 Subjective visual disturbances
0.683 0.316 0.000
H53.2 Diplopia
0.683 0.316 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
E87.5 Hyperkalaemia
0.683 0.317 0.000
Y84.6 Urinary catheterisation
0.683 0.317 0.000
H35.6 Retinal haemorrhage
0.682 0.318 0.000
G90.3 Multisystem degeneration
0.682 0.318 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.681 0.319 0.000
G96 Other disorders of central nervous system
0.680 0.320 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.677 0.322 0.000
F20.0 Paranoid schizophrenia
0.677 0.323 0.000
M05-M14 Inflammatory polyarthropathies
0.677 0.323 0.000
H16 Keratitis
0.677 0.323 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.676 0.324 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.676 0.324 0.000
E85 Amyloidosis
0.676 0.324 0.000
E84 Cystic fibrosis
0.676 0.324 0.000
E79 Disorders of purine and pyrimidine metabolism
0.676 0.324 0.000
E77 Disorders of glycoprotein metabolism
0.676 0.324 0.000
E76 Disorders of glycosaminoglycan metabolism
0.676 0.324 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.676 0.324 0.000
E73 Lactose intolerance
0.676 0.324 0.000
E72 Other disorders of amino-acid metabolism
0.676 0.324 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.676 0.324 0.000
E70 Disorders of aromatic amino-acid metabolism
0.676 0.324 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.676 0.324 0.000
L28 Lichen simplex chronicus and prurigo
0.675 0.325 0.000
L25 Unspecified contact dermatitis
0.675 0.325 0.000
L24 Irritant contact dermatitis
0.675 0.325 0.000
L23 Allergic contact dermatitis
0.675 0.325 0.000
L21 Seborrhoeic dermatitis
0.675 0.325 0.000
L20 Atopic dermatitis
0.675 0.325 0.000
L26 Exfoliative dermatitis
0.675 0.325 0.000
L22 Diaper [napkin] dermatitis
0.675 0.325 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.675 0.325 0.000
I42.6 Alcoholic cardiomyopathy
0.674 0.326 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.674 0.326 0.000
J90-J94 Other diseases of pleura
0.673 0.327 0.000
N37 Urethral disorders in diseases classified elsewhere
0.673 0.327 0.000
N34 Urethritis and urethral syndrome
0.673 0.327 0.000
N33 Bladder disorders in diseases classified elsewhere
0.673 0.327 0.000
H34.2 Other retinal artery occlusions
0.673 0.327 0.000
H54.4 Blindness, one eye
0.670 0.329 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.670 0.330 0.000
G30-G32 Other degenerative diseases of the nervous system
0.670 0.330 0.000
O75.9 Complication of labour and delivery, unspecified
0.668 0.331 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.668 0.331 0.000
O75.4 Other complications of obstetric surgery and procedures
0.668 0.331 0.000
O75.3 Other infection during labour
0.668 0.331 0.000
O75.1 Shock during or following labour and delivery
0.668 0.331 0.000
O75.0 Maternal distress during labour and delivery
0.668 0.331 0.000
I78 Diseases of capillaries
0.668 0.332 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.667 0.333 0.000
H53.6 Night blindness
0.667 0.333 0.000
H53.5 Colour vision deficiencies
0.667 0.333 0.000
H53.3 Other disorders of binocular vision
0.667 0.333 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.667 0.333 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.667 0.333 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.667 0.333 0.000
G92 Toxic encephalopathy
0.667 0.333 0.000
J35 Chronic diseases of tonsils and adenoids
0.667 0.333 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.666 0.333 0.000
H33.2 Serous retinal detachment
0.666 0.333 0.000
F20.9 Schizophrenia, unspecified
0.666 0.334 0.000
H21 Other disorders of iris and ciliary body
0.666 0.334 0.000
N04 Nephrotic syndrome
0.666 0.334 0.000
L89.1 Stage II decubitus ulcer
0.665 0.335 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.665 0.335 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.663 0.336 0.000
N39.2 Orthostatic proteinuria, unspecified
0.663 0.337 0.000
N39.1 Persistent proteinuria, unspecified
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.661 0.339 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.661 0.339 0.000
J20 Acute bronchitis
0.661 0.339 0.000
I20-I25 Ischaemic heart diseases
0.659 0.341 0.000
J37 Chronic laryngitis and laryngotracheitis
0.659 0.341 0.000
O32.1 Maternal care for breech presentation
0.658 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.658 0.342 0.000
H35.4 Peripheral retinal degeneration
0.658 0.342 0.000
I74 Arterial embolism and thrombosis
0.658 0.342 0.000
G91.1 Obstructive hydrocephalus
0.658 0.342 0.000
G93.3 Postviral fatigue syndrome
0.658 0.342 0.000
J81 Pulmonary oedema
0.657 0.343 0.000
N39.0 Urinary tract infection, site not specified
0.657 0.343 0.000
V80-V89 Other land transport accidents
0.657 0.343 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.657 0.343 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.657 0.343 0.000
H54.6 Unqualified visual loss, one eye
0.656 0.343 0.000
H54.5 Low vision, one eye
0.656 0.343 0.000
H54.3 Unqualified visual loss, both eyes
0.656 0.343 0.000
H54.2 Low vision, both eyes
0.656 0.343 0.000
H54.1 Blindness, one eye, low vision, other eye
0.656 0.343 0.000
O00 Ectopic pregnancy
0.656 0.344 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.344 0.000
L08 Other local infections of skin and subcutaneous tissue
0.656 0.344 0.000
N18.8 Other chronic renal failure
0.656 0.344 0.000
N18.1 Chronic kidney disease, stage 1
0.656 0.344 0.000
E13 Other specified diabetes mellitus
0.656 0.344 0.000
G93.9 Disorder of brain, unspecified
0.656 0.344 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.656 0.344 0.000
H20 Iridocyclitis
0.655 0.345 0.000
E16 Other disorders of pancreatic internal secretion
0.655 0.345 0.000
I13 Hypertensive heart and renal disease
0.654 0.345 0.000
I11 Hypertensive heart disease
0.654 0.345 0.000
M91-M94 Chondropathies
0.654 0.346 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.653 0.346 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.652 0.348 0.000
O15 Eclampsia
0.651 0.348 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.651 0.348 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.651 0.348 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.651 0.348 0.000
O70.9 Perineal laceration during delivery, unspecified
0.651 0.349 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.651 0.349 0.000
L94.2 Calcinosis cutis
0.650 0.349 0.000
E87.2 Acidosis
0.649 0.351 0.000
B35-B49 Mycoses
0.649 0.351 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.648 0.352 0.000
B02.2 Zoster with other nervous system involvement
0.648 0.352 0.000
N17.8 Other acute renal failure
0.648 0.352 0.000
N17.2 Acute renal failure with medullary necrosis
0.648 0.352 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.648 0.352 0.000
L89.2 Stage III decubitus ulcer
0.647 0.352 0.000
L90 Atrophic disorders of skin
0.647 0.353 0.000
I46.0 Cardiac arrest with successful resuscitation
0.647 0.353 0.000
H31.0 Chorioretinal scars
0.645 0.355 0.000
Chapter II Neoplasms
0.644 0.356 0.000
O73.0 Retained placenta, without haemorrhage
0.644 0.356 0.000
I69 Sequelae of cerebrovascular disease
0.643 0.356 0.000
E14 Unspecified diabetes mellitus
0.643 0.357 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.643 0.357 0.000
N27 Small kidney of unknown cause
0.643 0.357 0.000
N25 Disorders resulting from impaired renal tubular function
0.643 0.357 0.000
N26 Unspecified contracted kidney
0.643 0.357 0.000
F80-F89 Disorders of psychological development
0.642 0.358 0.000
F99-F99 Unspecified mental disorder
0.642 0.358 0.000
X60-X84 Intentional self-harm
0.642 0.358 0.000
W20-W49 Exposure to inanimate mechanical forces
0.642 0.358 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.641 0.359 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.640 0.360 0.000
Q66 Congenital deformities of feet
0.639 0.361 0.000
L84 Corns and callosities
0.639 0.361 0.000
N05 Unspecified nephritic syndrome
0.639 0.361 0.000
J30 Vasomotor and allergic rhinitis
0.638 0.361 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.638 0.362 0.000
Y35-Y36 Legal intervention and operations of war
0.638 0.362 0.000
Y10-Y34 Event of undetermined intent
0.638 0.362 0.000
Y00-Y09 Assault
0.638 0.362 0.000
X85-X99 Assault
0.638 0.362 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.638 0.362 0.000
X50-X57 Overexertion, travel and privation
0.638 0.362 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.638 0.362 0.000
X30-X39 Exposure to forces of nature
0.638 0.362 0.000
X20-X29 Contact with venomous animals and plants
0.638 0.362 0.000
X10-X19 Contact with heat and hot substances
0.638 0.362 0.000
X00-X09 Exposure to smoke, fire and flames
0.638 0.362 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.638 0.362 0.000
W75-W84 Other accidental threats to breathing
0.638 0.362 0.000
W65-W74 Accidental drowning and submersion
0.638 0.362 0.000
W50-W64 Exposure to animate mechanical forces
0.638 0.362 0.000
V98-V99 Other and unspecified transport accidents
0.638 0.362 0.000
V95-V97 Air and space transport accidents
0.638 0.362 0.000
V90-V94 Water transport accidents
0.638 0.362 0.000
V70-V79 Bus occupant injured in transport accident
0.638 0.362 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.638 0.362 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.638 0.362 0.000
V40-V49 Car occupant injured in transport accident
0.638 0.362 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.638 0.362 0.000
V01-V09 Pedestrian injured in transport accident
0.638 0.362 0.000
H35.7 Separation of retinal layers
0.638 0.362 0.000
H35.5 Hereditary retinal dystrophy
0.638 0.362 0.000
H35.2 Other proliferative retinopathy
0.638 0.362 0.000
H35.1 Retinopathy of prematurity
0.638 0.362 0.000
B07 Viral warts
0.638 0.362 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.637 0.363 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.636 0.363 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.636 0.364 0.000
I77.6 Arteritis, unspecified
0.636 0.364 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.634 0.366 0.000
I44.5 Left posterior fascicular block
0.633 0.367 0.000
I44.4 Left anterior fascicular block
0.633 0.367 0.000
I44.3 Other and unspecified atrioventricular block
0.633 0.367 0.000
B02.3 Zoster ocular disease
0.633 0.367 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.632 0.368 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.631 0.368 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.631 0.369 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.631 0.369 0.000
H55 Nystagmus and other irregular eye movements
0.631 0.369 0.000
I95 Hypotension
0.631 0.369 0.000
O04.9 Complete or unspecified, without complication
0.630 0.370 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.629 0.371 0.000
L27.8 Dermatitis due to other substances taken internally
0.629 0.371 0.000
L27.2 Dermatitis due to ingested food
0.629 0.371 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.629 0.371 0.000
J21 Acute bronchiolitis
0.628 0.371 0.000
H53.9 Visual disturbance, unspecified
0.628 0.372 0.000
F25 Schizoaffective disorders
0.628 0.372 0.000
O80 Single spontaneous delivery
0.628 0.372 0.000
E87.4 Mixed disorder of acid-base balance
0.627 0.373 0.000
E87.3 Alkalosis
0.627 0.373 0.000
I51.8 Other ill-defined heart diseases
0.626 0.374 0.000
I70.0 Atherosclerosis of aorta
0.625 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.624 0.375 0.000
Q80-Q89 Other congenital malformations
0.624 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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